EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000123200 (Gene tree)
Gene ID: 23091
Gene Symbol: ZC3H13
Alias: DKFZp434D1812|Xio|KIAA0853
Full Name: zinc finger CCCH-type containing 13
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 98,297 bases
Position: chr13:45,954,465-46,052,761
Accession: 20368
RBP type: canonical RBP
Summary: (Zinc Finger CCCH-Type Containing 13) is a Protein Coding gene. Diseases associated with ZC3H13 include Wilms Tumor 1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000416238	zf-CCCH	PF00642.24	9.6e-08	1	1
ENSP00000282007	zf-CCCH	PF00642.24	2.4e-06	1	1
ENSP00000242848	zf-CCCH	PF00642.24	2.6e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000470308	ZC3H13-205	795	-	-	- (aa)	-	-
ENST00000242848	ZC3H13-201	8018	XM_005266301	ENSP00000242848	1668 (aa)	XP_005266358	Q5T200
ENST00000282007	ZC3H13-202	6412	-	ENSP00000282007	1564 (aa)	-	Q5T200
ENST00000464597	ZC3H13-204	535	-	ENSP00000480658	116 (aa)	-	A0A087WX14
ENST00000428921	ZC3H13-203	695	-	ENSP00000416238	115 (aa)	-	Q5T9K0

Gene Model

Click here to download ENSG00000123200's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000123200	rs2094247	13	46028027	?	Blood protein levels	28240269			EFO_0008069
ENSG00000123200	rs9534288	13	46031306	T	Blood protein levels	28240269	[0.5-0.69] unit decrease	0.5958	EFO_0008069
ENSG00000123200	rs12585823	13	45962156	G	Blood protein levels	28240269	[0.41-0.73] unit increase	0.5688	EFO_0008226
ENSG00000123200	rs5803322	13	46008320	C	Blood protein levels	29875488	[0.14-0.26] unit decrease	0.2	EFO_0007937

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000123200's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000123200	ZC3H13	100	97.482	ENSANAG00000033079	ZC3H13	100	97.482	Aotus_nancymaae
ENSG00000123200	ZC3H13	100	96.944	ENSCJAG00000016756	ZC3H13	100	96.944	Callithrix_jacchus
ENSG00000123200	ZC3H13	98	99.115	ENSCAFG00020019269	ZC3H13	99	96.445	Canis_lupus_dingo
ENSG00000123200	ZC3H13	98	98.230	ENSCCAG00000032728	ZC3H13	54	95.692	Cebus_capucinus
ENSG00000123200	ZC3H13	100	98.501	ENSCATG00000041075	ZC3H13	100	98.501	Cercocebus_atys
ENSG00000123200	ZC3H13	100	98.502	ENSCSAG00000017764	ZC3H13	100	98.502	Chlorocebus_sabaeus
ENSG00000123200	ZC3H13	98	96.460	ENSCHOG00000009724	ZC3H13	65	96.460	Choloepus_hoffmanni
ENSG00000123200	ZC3H13	100	98.562	ENSCANG00000037422	ZC3H13	100	98.562	Colobus_angolensis_palliatus
ENSG00000123200	ZC3H13	98	96.460	ENSCGRG00001014490	Zc3h13	80	87.908	Cricetulus_griseus_chok1gshd
ENSG00000123200	ZC3H13	98	96.460	ENSCGRG00000002575	Zc3h13	80	87.908	Cricetulus_griseus_crigri
ENSG00000123200	ZC3H13	97	74.336	ENSGACG00000015166	zc3h13	74	53.497	Gasterosteus_aculeatus
ENSG00000123200	ZC3H13	100	99.341	ENSGGOG00000005496	ZC3H13	100	99.341	Gorilla_gorilla
ENSG00000123200	ZC3H13	97	65.873	ENSKMAG00000010701	zc3h13	60	47.346	Kryptolebias_marmoratus
ENSG00000123200	ZC3H13	98	84.071	ENSLACG00000003806	ZC3H13	58	63.739	Latimeria_chalumnae
ENSG00000123200	ZC3H13	100	98.501	ENSMFAG00000004060	ZC3H13	100	98.501	Macaca_fascicularis
ENSG00000123200	ZC3H13	100	99.130	ENSMMUG00000017025	ZC3H13	100	98.529	Macaca_mulatta
ENSG00000123200	ZC3H13	100	98.441	ENSMNEG00000044356	ZC3H13	100	98.441	Macaca_nemestrina
ENSG00000123200	ZC3H13	98	99.123	ENSMLEG00000039387	ZC3H13	100	95.084	Mandrillus_leucophaeus
ENSG00000123200	ZC3H13	98	93.805	MGP_CAROLIEiJ_G0019512	Zc3h13	50	80.248	Mus_caroli
ENSG00000123200	ZC3H13	98	93.805	ENSMUSG00000022000	Zc3h13	50	80.023	Mus_musculus
ENSG00000123200	ZC3H13	98	93.805	MGP_PahariEiJ_G0030530	Zc3h13	50	79.910	Mus_pahari
ENSG00000123200	ZC3H13	98	93.805	MGP_SPRETEiJ_G0020407	Zc3h13	51	80.023	Mus_spretus
ENSG00000123200	ZC3H13	100	99.361	ENSNLEG00000002498	ZC3H13	100	99.361	Nomascus_leucogenys
ENSG00000123200	ZC3H13	98	100.000	ENSPPAG00000034465	ZC3H13	100	95.926	Pan_paniscus
ENSG00000123200	ZC3H13	98	99.115	ENSPTIG00000014867	ZC3H13	53	84.485	Panthera_tigris_altaica
ENSG00000123200	ZC3H13	100	99.820	ENSPTRG00000005851	ZC3H13	100	99.820	Pan_troglodytes
ENSG00000123200	ZC3H13	100	97.722	ENSPANG00000014127	ZC3H13	100	97.722	Papio_anubis
ENSG00000123200	ZC3H13	98	97.345	ENSPSIG00000012518	ZC3H13	99	75.714	Pelodiscus_sinensis
ENSG00000123200	ZC3H13	98	96.460	ENSPEMG00000021979	-	99	93.541	Peromyscus_maniculatus_bairdii
ENSG00000123200	ZC3H13	98	98.230	ENSPCAG00000001146	ZC3H13	77	95.161	Procavia_capensis
ENSG00000123200	ZC3H13	98	97.345	ENSPVAG00000012353	ZC3H13	69	85.100	Pteropus_vampyrus
ENSG00000123200	ZC3H13	98	94.690	ENSRNOG00000011237	Zc3h13	50	77.716	Rattus_norvegicus
ENSG00000123200	ZC3H13	99	99.130	ENSRBIG00000010463	ZC3H13	100	98.022	Rhinopithecus_bieti
ENSG00000123200	ZC3H13	100	97.305	ENSSBOG00000027228	ZC3H13	100	97.305	Saimiri_boliviensis_boliviensis
ENSG00000123200	ZC3H13	97	65.116	ENSSMAG00000007110	zc3h13	55	58.203	Scophthalmus_maximus
ENSG00000123200	ZC3H13	98	67.717	ENSSDUG00000021808	zc3h13	91	58.352	Seriola_dumerili
ENSG00000123200	ZC3H13	98	97.345	ENSVPAG00000005179	ZC3H13	61	92.727	Vicugna_pacos
ENSG00000123200	ZC3H13	98	87.611	ENSXETG00000014637	zc3h13	99	63.984	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	20195357.	IPI	Function
GO:0005654	nucleoplasm	24100041.	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0016607	nuclear speck	21873635.	IBA	Component
GO:0016607	nuclear speck	24100041.	IDA	Component
GO:0036396	RNA N6-methyladenosine methyltransferase complex	29507755.	IDA	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0080009	mRNA methylation	29507755.	IMP	Process
GO:2000036	regulation of stem cell population maintenance	-	ISS	Process