EuRBPDB

Description

Ensembl ID: ENSG00000124201 (Gene tree)
Gene ID: 57169
Gene Symbol: ZNFX1
Alias: KIAA1404|FLJ11277
Full Name: zinc finger NFX1-type containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 40,481 bases
Position: chr20:49,237,946-49,278,426
Accession: 29271
RBP type: non-canonical RBP
Summary: (Zinc Finger NFX1-Type Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is AQR.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000455070	ZNFX1-205	2122	-	ENSP00000413800	707 (aa)	-	Q5JXR7
ENST00000469991	ZNFX1-206	640	-	-	- (aa)	-	-
ENST00000371754	ZNFX1-203	5235	-	ENSP00000360819	1270 (aa)	-	Q5JXR6
ENST00000371752	ZNFX1-202	7212	XM_006723836	ENSP00000360817	1918 (aa)	XP_006723899	Q9P2E3
ENST00000396105	ZNFX1-204	7371	XM_011528924	ENSP00000379412	1918 (aa)	XP_011527226	Q9P2E3
ENST00000371744	ZNFX1-201	2964	-	ENSP00000360809	934 (aa)	-	Q5JXR5

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000124201	Body Height	1E-9	25281659

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124201	rs1567865	20	49265430	T	Infant length	25281659	[0.043-0.083] unit increase	0.063	EFO_0006785
ENSG00000124201	rs6122773	20	49250119	A	General cognitive ability	29844566	z-score decrease	5.759	EFO_0004337

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124201	ZNFX1	100	87.643	ENSMUSG00000039501	Znfx1	100	87.643	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000775	chromosome, centromeric region	-	IEA	Component
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0030702	chromatin silencing at centromere	21873635.	IBA	Process
GO:0031048	chromatin silencing by small RNA	21873635.	IBA	Process
GO:0031380	nuclear RNA-directed RNA polymerase complex	21873635.	IBA	Component