EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000124209 (Gene tree)
Gene ID: 57403
Gene Symbol: RAB22A
Alias: -
Full Name: RAB22A, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 57,812 bases
Position: chr20:58,309,696-58,367,507
Accession: 9764
RBP type: canonical RBP
Summary: The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000244040	MMR_HSR1	PF01926.23	0.00023	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000244040	RAB22A-201	8670	-	ENSP00000244040	194 (aa)	-	Q9UL26
ENST00000488949	RAB22A-202	1032	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000124209's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000124209	Hemoglobin A, Glycosylated	1.5020000E-005	19875614
ENSG00000124209	Diabetes Mellitus	6.3180000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124209	rs707557	20	58367256	?	Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer	28763429	[0.83-2.08] unit increase	1.46	EFO_0008347\|EFO_0008204\|GO_1901555

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124209's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124209	RAB22A	100	88.660	ENSAPOG00000011559	rab22a	100	88.660	Acanthochromis_polyacanthus
ENSG00000124209	RAB22A	100	84.536	ENSACIG00000014012	rab22a	99	84.536	Amphilophus_citrinellus
ENSG00000124209	RAB22A	100	88.660	ENSAOCG00000001554	rab22a	100	88.660	Amphiprion_ocellaris
ENSG00000124209	RAB22A	100	88.660	ENSAPEG00000011209	rab22a	100	88.660	Amphiprion_percula
ENSG00000124209	RAB22A	100	89.691	ENSATEG00000025079	rab22a	100	89.691	Anabas_testudineus
ENSG00000124209	RAB22A	100	95.876	ENSACAG00000014624	RAB22A	100	95.876	Anolis_carolinensis
ENSG00000124209	RAB22A	99	99.482	ENSANAG00000034725	RAB22A	99	99.482	Aotus_nancymaae
ENSG00000124209	RAB22A	100	87.629	ENSACLG00000021470	rab22a	100	87.629	Astatotilapia_calliptera
ENSG00000124209	RAB22A	100	87.310	ENSAMXG00000013054	rab22a	100	87.310	Astyanax_mexicanus
ENSG00000124209	RAB22A	100	98.454	ENSBTAG00000018053	RAB22A	100	98.454	Bos_taurus
ENSG00000124209	RAB22A	100	99.485	ENSCJAG00000044464	RAB22A	100	99.485	Callithrix_jacchus
ENSG00000124209	RAB22A	100	98.454	ENSCAFG00020022020	RAB22A	100	98.454	Canis_lupus_dingo
ENSG00000124209	RAB22A	100	98.454	ENSCHIG00000017305	RAB22A	100	98.454	Capra_hircus
ENSG00000124209	RAB22A	100	98.969	ENSTSYG00000034530	-	100	98.969	Carlito_syrichta
ENSG00000124209	RAB22A	100	98.969	ENSCPOG00000008172	RAB22A	100	98.969	Cavia_porcellus
ENSG00000124209	RAB22A	100	99.485	ENSCCAG00000030930	RAB22A	100	99.485	Cebus_capucinus
ENSG00000124209	RAB22A	100	99.485	ENSCATG00000011350	RAB22A	100	99.485	Cercocebus_atys
ENSG00000124209	RAB22A	100	99.485	ENSCSAG00000015545	RAB22A	100	99.485	Chlorocebus_sabaeus
ENSG00000124209	RAB22A	100	96.392	ENSCPBG00000023927	RAB22A	100	96.392	Chrysemys_picta_bellii
ENSG00000124209	RAB22A	100	99.485	ENSCANG00000032052	RAB22A	100	99.485	Colobus_angolensis_palliatus
ENSG00000124209	RAB22A	100	97.938	ENSCGRG00001020667	Rab22a	100	97.938	Cricetulus_griseus_chok1gshd
ENSG00000124209	RAB22A	100	89.691	ENSCSEG00000019797	rab22a	100	89.691	Cynoglossus_semilaevis
ENSG00000124209	RAB22A	100	86.598	ENSCVAG00000018433	rab22a	100	86.598	Cyprinodon_variegatus
ENSG00000124209	RAB22A	100	86.735	ENSDARG00000015807	rab22a	100	86.735	Danio_rerio
ENSG00000124209	RAB22A	100	97.938	ENSEASG00005023252	RAB22A	100	97.938	Equus_asinus_asinus
ENSG00000124209	RAB22A	100	89.175	ENSELUG00000015343	rab22a	100	89.175	Esox_lucius
ENSG00000124209	RAB22A	100	97.423	ENSFCAG00000046416	RAB22A	100	97.423	Felis_catus
ENSG00000124209	RAB22A	100	86.598	ENSFHEG00000012702	rab22a	100	86.598	Fundulus_heteroclitus
ENSG00000124209	RAB22A	100	86.082	ENSGMOG00000013070	rab22a	100	86.082	Gadus_morhua
ENSG00000124209	RAB22A	100	96.392	ENSGALG00000007554	RAB22A	100	96.392	Gallus_gallus
ENSG00000124209	RAB22A	100	86.082	ENSGAFG00000001301	rab22a	100	86.082	Gambusia_affinis
ENSG00000124209	RAB22A	100	88.660	ENSGACG00000005608	rab22a	100	88.660	Gasterosteus_aculeatus
ENSG00000124209	RAB22A	100	95.361	ENSGAGG00000018569	RAB22A	100	95.361	Gopherus_agassizii
ENSG00000124209	RAB22A	100	99.485	ENSGGOG00000015533	RAB22A	100	99.485	Gorilla_gorilla
ENSG00000124209	RAB22A	100	87.629	ENSHBUG00000003434	rab22a	80	87.629	Haplochromis_burtoni
ENSG00000124209	RAB22A	100	97.938	ENSHGLG00000009337	RAB22A	100	97.938	Heterocephalus_glaber_female
ENSG00000124209	RAB22A	100	89.175	ENSHCOG00000001145	rab22a	100	89.175	Hippocampus_comes
ENSG00000124209	RAB22A	100	83.163	ENSIPUG00000010794	rab22a	99	83.163	Ictalurus_punctatus
ENSG00000124209	RAB22A	100	94.330	ENSJJAG00000011551	-	100	94.330	Jaculus_jaculus
ENSG00000124209	RAB22A	100	86.598	ENSKMAG00000014705	rab22a	100	86.598	Kryptolebias_marmoratus
ENSG00000124209	RAB22A	100	88.660	ENSLBEG00000003235	rab22a	100	88.660	Labrus_bergylta
ENSG00000124209	RAB22A	100	93.299	ENSLACG00000007092	RAB22A	100	93.299	Latimeria_chalumnae
ENSG00000124209	RAB22A	100	90.722	ENSLOCG00000007029	rab22a	100	90.722	Lepisosteus_oculatus
ENSG00000124209	RAB22A	100	97.423	ENSLAFG00000003688	RAB22A	100	97.423	Loxodonta_africana
ENSG00000124209	RAB22A	100	98.969	ENSMFAG00000044247	RAB22A	100	98.969	Macaca_fascicularis
ENSG00000124209	RAB22A	100	99.485	ENSMMUG00000000125	RAB22A	100	99.485	Macaca_mulatta
ENSG00000124209	RAB22A	100	99.485	ENSMNEG00000028401	RAB22A	100	99.485	Macaca_nemestrina
ENSG00000124209	RAB22A	100	99.485	ENSMLEG00000035868	RAB22A	100	99.485	Mandrillus_leucophaeus
ENSG00000124209	RAB22A	100	89.691	ENSMAMG00000006024	rab22a	100	89.691	Mastacembelus_armatus
ENSG00000124209	RAB22A	100	87.629	ENSMZEG00005004122	rab22a	100	87.629	Maylandia_zebra
ENSG00000124209	RAB22A	100	97.938	ENSMAUG00000008648	Rab22a	100	97.938	Mesocricetus_auratus
ENSG00000124209	RAB22A	100	99.485	ENSMICG00000008382	-	100	99.485	Microcebus_murinus
ENSG00000124209	RAB22A	100	97.938	ENSMOCG00000012268	Rab22a	100	97.938	Microtus_ochrogaster
ENSG00000124209	RAB22A	100	89.175	ENSMMOG00000004059	rab22a	100	89.175	Mola_mola
ENSG00000124209	RAB22A	100	97.938	ENSMODG00000016544	RAB22A	100	97.938	Monodelphis_domestica
ENSG00000124209	RAB22A	100	89.691	ENSMALG00000011693	rab22a	100	89.691	Monopterus_albus
ENSG00000124209	RAB22A	100	97.423	MGP_CAROLIEiJ_G0024752	Rab22a	100	97.423	Mus_caroli
ENSG00000124209	RAB22A	100	97.423	ENSMUSG00000027519	Rab22a	100	97.423	Mus_musculus
ENSG00000124209	RAB22A	100	97.423	MGP_PahariEiJ_G0026193	Rab22a	100	97.423	Mus_pahari
ENSG00000124209	RAB22A	100	97.423	MGP_SPRETEiJ_G0025672	Rab22a	100	97.423	Mus_spretus
ENSG00000124209	RAB22A	100	97.938	ENSNGAG00000012652	Rab22a	100	97.938	Nannospalax_galili
ENSG00000124209	RAB22A	100	97.938	ENSODEG00000000054	RAB22A	100	97.938	Octodon_degus
ENSG00000124209	RAB22A	100	87.629	ENSONIG00000006876	rab22a	100	87.629	Oreochromis_niloticus
ENSG00000124209	RAB22A	100	98.454	ENSOGAG00000015779	RAB22A	100	98.454	Otolemur_garnettii
ENSG00000124209	RAB22A	100	98.454	ENSOARG00000017194	RAB22A	100	98.454	Ovis_aries
ENSG00000124209	RAB22A	100	99.485	ENSPPAG00000030833	RAB22A	100	99.485	Pan_paniscus
ENSG00000124209	RAB22A	100	97.423	ENSPPRG00000016807	RAB22A	100	97.423	Panthera_pardus
ENSG00000124209	RAB22A	100	99.485	ENSPTRG00000044969	RAB22A	100	99.485	Pan_troglodytes
ENSG00000124209	RAB22A	100	99.485	ENSPANG00000022760	RAB22A	100	99.485	Papio_anubis
ENSG00000124209	RAB22A	100	88.660	ENSPKIG00000004103	rab22a	100	88.660	Paramormyrops_kingsleyae
ENSG00000124209	RAB22A	100	94.330	ENSPSIG00000009912	RAB22A	100	94.330	Pelodiscus_sinensis
ENSG00000124209	RAB22A	100	88.144	ENSPMGG00000001591	rab22a	100	88.144	Periophthalmus_magnuspinnatus
ENSG00000124209	RAB22A	100	97.938	ENSPEMG00000000644	Rab22a	100	97.938	Peromyscus_maniculatus_bairdii
ENSG00000124209	RAB22A	100	97.938	ENSPCIG00000004714	RAB22A	100	97.938	Phascolarctos_cinereus
ENSG00000124209	RAB22A	100	86.598	ENSPLAG00000017232	rab22a	100	86.598	Poecilia_latipinna
ENSG00000124209	RAB22A	100	86.598	ENSPLAG00000018718	rab22a	100	86.598	Poecilia_latipinna
ENSG00000124209	RAB22A	100	86.598	ENSPMEG00000003743	rab22a	100	86.598	Poecilia_mexicana
ENSG00000124209	RAB22A	100	86.598	ENSPREG00000010920	rab22a	100	86.598	Poecilia_reticulata
ENSG00000124209	RAB22A	100	99.485	ENSPPYG00000011171	RAB22A	100	99.485	Pongo_abelii
ENSG00000124209	RAB22A	100	99.485	ENSPCOG00000019205	RAB22A	100	99.485	Propithecus_coquereli
ENSG00000124209	RAB22A	100	87.245	ENSPNAG00000015161	rab22a	100	87.245	Pygocentrus_nattereri
ENSG00000124209	RAB22A	100	96.392	ENSRNOG00000005762	Rab22a	100	96.392	Rattus_norvegicus
ENSG00000124209	RAB22A	100	99.485	ENSRBIG00000037689	RAB22A	100	99.485	Rhinopithecus_bieti
ENSG00000124209	RAB22A	100	99.485	ENSRROG00000043562	RAB22A	100	99.485	Rhinopithecus_roxellana
ENSG00000124209	RAB22A	100	97.938	ENSSHAG00000016302	RAB22A	100	97.938	Sarcophilus_harrisii
ENSG00000124209	RAB22A	100	88.660	ENSSFOG00015012085	rab22a	100	88.660	Scleropages_formosus
ENSG00000124209	RAB22A	100	89.691	ENSSMAG00000010140	rab22a	100	89.691	Scophthalmus_maximus
ENSG00000124209	RAB22A	100	89.175	ENSSDUG00000017131	rab22a	100	89.175	Seriola_dumerili
ENSG00000124209	RAB22A	100	89.691	ENSSLDG00000020438	rab22a	100	89.691	Seriola_lalandi_dorsalis
ENSG00000124209	RAB22A	100	95.361	ENSSPUG00000000017	RAB22A	100	95.361	Sphenodon_punctatus
ENSG00000124209	RAB22A	100	88.660	ENSSPAG00000021333	rab22a	100	88.660	Stegastes_partitus
ENSG00000124209	RAB22A	100	98.454	ENSSSCG00000007513	RAB22A	100	98.454	Sus_scrofa
ENSG00000124209	RAB22A	100	95.876	ENSTGUG00000008195	RAB22A	100	95.876	Taeniopygia_guttata
ENSG00000124209	RAB22A	100	87.629	ENSTRUG00000018380	rab22a	100	87.629	Takifugu_rubripes
ENSG00000124209	RAB22A	100	88.144	ENSTNIG00000018267	rab22a	100	88.144	Tetraodon_nigroviridis
ENSG00000124209	RAB22A	100	98.454	ENSTTRG00000015587	RAB22A	100	98.454	Tursiops_truncatus
ENSG00000124209	RAB22A	100	86.598	ENSXCOG00000016452	rab22a	100	86.598	Xiphophorus_couchianus
ENSG00000124209	RAB22A	100	86.598	ENSXMAG00000021095	rab22a	100	86.598	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001726	ruffle	-	IEA	Component
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0003924	GTPase activity	24466322.	IMP	Function
GO:0003924	GTPase activity	11870209.	TAS	Function
GO:0005515	protein binding	11870209.16189514.25416956.	IPI	Function
GO:0005525	GTP binding	24466322.	IMP	Function
GO:0005769	early endosome	21873635.	IBA	Component
GO:0005769	early endosome	11870209.	IDA	Component
GO:0005770	late endosome	-	IEA	Component
GO:0005886	plasma membrane	11870209.	IDA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0006897	endocytosis	21873635.	IBA	Process
GO:0006897	endocytosis	11870209.	IDA	Process
GO:0007032	endosome organization	11870209.	IEP	Process
GO:0010008	endosome membrane	-	IEA	Component
GO:0015629	actin cytoskeleton	-	IEA	Component
GO:0019003	GDP binding	20937701.	IDA	Function
GO:0030670	phagocytic vesicle membrane	-	IEA	Component
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0045335	phagocytic vesicle	21255211.	IDA	Component
GO:0070062	extracellular exosome	19056867.19199708.	HDA	Component
GO:0097494	regulation of vesicle size	24466322.	IMP	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25294901	miR-204-5p inhibits proliferation and invasion and enhances chemotherapeutic sensitivity of colorectal cancer cells by downregulating RAB22A.	Clin Cancer Res	2014 Dec 1	Yin Y	doi: 10.1158/1078-0432.CCR-14-1030
25550792	Tumor suppressive microRNA-193b promotes breast cancer progression via targeting DNAJC13 and RAB22A.	Int J Clin Exp Pathol	2014 Oct 15	Yang Z	-
25429829	MicroRNA-204-5p inhibits gastric cancer cell proliferation by downregulating USP47 and RAB22A.	Med Oncol	2015 Jan	Zhang B	doi: 10.1007/s12032-014-0331-y
26382657	miR-203 Acts as a Tumor Suppressor Gene in Osteosarcoma by Regulating RAB22A.	PLoS One	2015 Sep 18	Yang D	doi: 10.1371/journal.pone.0132225
30272274	Regulation of RAB22A by mir-193b inhibits breast cancer growth and metastasis mediated by exosomes.	Int J Oncol	2018 Dec	Sun L	doi: 10.3892/ijo.2018.4571
24938788	Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.	Proc Natl Acad Sci U S A	2014 Aug 5	Wang T	doi: 10.1073/pnas.1410041111
25460499	MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer.	Oncotarget	2014 Dec 15	Zhang Y	-
27484896	LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer.	Mol Med Rep	2016 Sep	Zhang Z	doi: 10.3892/mmr.2016.5572
28433697	Rab22a enhances CD147 recycling and is required for lung cancer cell migration and invasion.	Exp Cell Res	2017 Aug 1	Zhou Y	doi: 10.1016/j.yexcr.2017.04.020

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr20	58343721	Silent	novel	A40A	0.57
BLCA	chr20	58343779	Missense_Mutation	novel	D60N	0.17	MMR_HSR1
BLCA	chr20	58353276	Missense_Mutation	NA	R68C	0.48	MMR_HSR1
BLCA	chr20	58311043	Missense_Mutation	novel	D13Y	0.1	MMR_HSR1
BRCA	chr20	58354215	Missense_Mutation	NA	E146A	0.22
BRCA	chr20	58354216	Missense_Mutation	NA	E146D	0.22
CESC	chr20	58360519	3'UTR	novel		0.29
CESC	chr20	58354157	Missense_Mutation	NA	E127Q	0.43
CESC	chr20	58360464	3'UTR	novel		0.38
CESC	chr20	58361257	3'UTR	novel		0.35
CESC	chr20	58311097	Missense_Mutation	novel	D31H	0.51	MMR_HSR1
CESC	chr20	58360480	3'UTR	novel		0.45
CHOL	chr20	58354206	Frame_Shift_Del	novel	*F144Lfs2**	0.33
CHOL	chr20	58360845	3'UTR	novel		0.22
COAD	chr20	58309944	5'UTR	novel		0.1
COAD	chr20	58353300	Nonsense_Mutation	NA	R76*	0.35	MMR_HSR1
COAD	chr20	58353530	Silent	NA	I123I	0.34
COAD	chr20	58354224	Frame_Shift_Ins	novel	*N151Kfs7**	0.19
COAD	chr20	58354225	Frame_Shift_Del	NA	*N151Tfs3**	0.26
COAD	chr20	58354234	Silent	rs377712985	A152A	0.2
DLBC	chr20	58354213	Silent	rs759870210	V145V	0.19
DLBC	chr20	58353481	Missense_Mutation	novel	G107D	0.42	MMR_HSR1
ESCA	chr20	58360522	3'UTR	novel		0.32
ESCA	chr20	58360483	3'UTR	novel		0.24
ESCA	chr20	58366910	3'UTR	novel		0.23
ESCA	chr20	58361188	3'UTR	novel		0.22
HNSC	chr20	58354195	Frame_Shift_Del	novel	*I140Mfs5**	0.36
LUAD	chr20	58354168	Missense_Mutation	novel	E130D	0.48
LUSC	chr20	58311070	Missense_Mutation	novel	V22L	0.39	MMR_HSR1
LUSC	chr20	58311097	Missense_Mutation	novel	D31N	0.4	MMR_HSR1
OV	chr20	58360102	3'UTR	novel		0.18
OV	chr20	58359807	3'UTR	novel		0.38
SKCM	chr20	58353330	Missense_Mutation	novel	D86Y	0.3	MMR_HSR1
SKCM	chr20	58359608	Nonsense_Mutation	rs766812693	R164*	0.56
SKCM	chr20	58311100	Missense_Mutation	NA	P32S	0.06	MMR_HSR1
SKCM	chr20	58353276	Missense_Mutation	NA	R68C	0.42	MMR_HSR1
SKCM	chr20	58359664	Silent	NA	L182L	0.42
STAD	chr20	58343799	Splice_Region	NA	R66R	0.21
STAD	chr20	58343799	Frame_Shift_Ins	novel	*G77Vfs20**	0.17	MMR_HSR1
STAD	chr20	58311097	Missense_Mutation	NA	D31Y	0.42	MMR_HSR1
STAD	chr20	58354222	Silent	rs138266092	S148S	0.14
STAD	chr20	58354249	Silent	NA	E157E	0.21
STAD	chr20	58353324	Missense_Mutation	NA	V84I	0.06	MMR_HSR1
THYM	chr20	58364071	3'UTR	novel		0.07
UCEC	chr20	58354233	Missense_Mutation	novel	A152E	0.09
UCEC	chr20	58360307	3'UTR	novel		0.15
UCEC	chr20	58361162	3'UTR	novel		0.23
UCEC	chr20	58359979	3'UTR	novel		0.42
UCEC	chr20	58360991	3'UTR	novel		0.35
UCEC	chr20	58361194	3'UTR	novel		0.1
UCEC	chr20	58353300	Nonsense_Mutation	NA	R76*	0.32	MMR_HSR1
UCEC	chr20	58359908	3'UTR	novel		0.25
UCEC	chr20	58360946	3'UTR	novel		0.13
UCEC	chr20	58359672	Missense_Mutation	NA	Q185P	0.5
UCEC	chr20	58353518	Silent	NA	K119K	0.15
UCEC	chr20	58309230	5'Flank	novel		0.38
UCEC	chr20	58353471	Nonsense_Mutation	NA	R104*	0.08	MMR_HSR1
UCEC	chr20	58361157	3'UTR	novel		0.4
UCEC	chr20	58363960	3'UTR	novel		0.18
UCEC	chr20	58367410	3'UTR	novel		0.28
UCEC	chr20	58364088	3'UTR	novel		0.5
UCEC	chr20	58361172	3'UTR	novel		0.34
UCEC	chr20	58364164	3'UTR	novel		0.32
UCEC	chr20	58366803	3'UTR	novel		0.43
UCEC	chr20	58359899	3'UTR	novel		0.19
UCEC	chr20	58366920	3'UTR	novel		0.38
UCEC	chr20	58361362	3'UTR	novel		0.42
UCEC	chr20	58367032	3'UTR	novel		0.33
UCEC	chr20	58360522	3'UTR	novel		0.36
UCEC	chr20	58360647	3'UTR	novel		0.41
UCEC	chr20	58363954	3'UTR	novel		0.33
UCEC	chr20	58360107	3'UTR	novel		0.17
UCEC	chr20	58359766	3'UTR	novel		0.27
UCEC	chr20	58354222	Silent	rs138266092	S148S	0.2
UCEC	chr20	58359722	3'UTR	novel		0.31
UCEC	chr20	58359666	Missense_Mutation	rs148684735	R183Q	0.1
UCEC	chr20	58364024	3'UTR	rs543941204		0.25
UCEC	chr20	58360725	3'UTR	rs535043755		0.41
UCEC	chr20	58360522	3'UTR	novel		0.53
UCEC	chr20	58353472	Missense_Mutation	rs573426413	R104Q	0.24	MMR_HSR1
UCEC	chr20	58363954	3'UTR	novel		0.32
UCEC	chr20	58359931	3'UTR	rs563422682		0.6
UCEC	chr20	58354233	Missense_Mutation	rs373476700	A152V	0.4
UCEC	chr20	58360670	3'UTR	novel		0.32
UCEC	chr20	58367020	3'UTR	novel		0.36
UCEC	chr20	58354222	Silent	rs138266092	S148S	0.42
UCEC	chr20	58354157	Nonsense_Mutation	novel	E127*	0.33
UCEC	chr20	58353468	Missense_Mutation	NA	L103I	0.22	MMR_HSR1
UCEC	chr20	58367102	3'UTR	novel		0.22
UCEC	chr20	58360522	3'UTR	novel		0.45
UCEC	chr20	58359638	Missense_Mutation	novel	P174S	0.09
UCEC	chr20	58360522	3'UTR	novel		0.27
UCEC	chr20	58360639	3'UTR	novel		0.27
UCEC	chr20	58353471	Nonsense_Mutation	NA	R104*	0.16	MMR_HSR1
UCEC	chr20	58354233	Missense_Mutation	rs373476700	A152V	0.48
UCEC	chr20	58361173	3'UTR	novel		0.67
UCEC	chr20	58353530	Silent	NA	I123I	0.36
UCEC	chr20	58360732	3'UTR	novel		0.49
UCEC	chr20	58367032	3'UTR	novel		0.67
UCEC	chr20	58367455	3'UTR	novel		0.35
UCEC	chr20	58360718	3'UTR	novel		0.41
UCEC	chr20	58309254	5'Flank	novel		0.21
UCS	chr20	58354253	Missense_Mutation	novel	F159V	0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PRAD	AMP	0.0528	0.07085
SARC	AMP	0.3307	0.033553
SKCM	AMP	0.4496	0.058021

Survival Analysis

Cancer	P-value	Q-value
SARC	0.01	Kaplan-Meier Survival Analysis
MESO	0.043	Kaplan-Meier Survival Analysis
SKCM	0.00045	Kaplan-Meier Survival Analysis
PRAD	0.017	Kaplan-Meier Survival Analysis
PAAD	0.023	Kaplan-Meier Survival Analysis
BLCA	0.0091	Kaplan-Meier Survival Analysis
LAML	0.022	Kaplan-Meier Survival Analysis
KICH	0.038	Kaplan-Meier Survival Analysis
UCEC	0.004	Kaplan-Meier Survival Analysis
LIHC	0.0016	Kaplan-Meier Survival Analysis
UVM	0.0069	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742