EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000124562 (Gene tree)
Gene ID: 6631
Gene Symbol: SNRPC
Alias: U1-C|Yhc1
Full Name: small nuclear ribonucleoprotein polypeptide C
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 16,764 bases
Position: chr6:34,757,094-34,773,857
Accession: 11157
RBP type: canonical RBP
Summary: This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.[provided by RefSeq, Oct 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000244520	zf-U1	PF06220.12	4.1e-22	1	1
ENSP00000363129	zf-U1	PF06220.12	1e-19	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
1826349	Zinc finger-like structure in U1-specific protein C is essential for specific binding to U1 snRNP.	Nucleic Acids Res	1991 Feb 11	Nelissen RL	-
19325628	Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.	Nature	2009 Mar 26	Pomeranz Krummel DA	doi: 10.1038/nature07851.
25555158	Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.	Elife	2015 Jan 2	Kondo Y	doi: 10.7554/eLife.04986.
24748659	Genome-wide RNA-binding analysis of the trypanosome U1 snRNP proteins U1C and U1-70K reveals cis/trans-spliceosomal network.	Nucleic Acids Res	2014 Jun	PreuBer C	doi: 10.1093/nar/gku286
15465910	Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation.	Proc Natl Acad Sci U S A	2004 Oct 12	Du H	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374017	SNRPC-202	1054	-	ENSP00000363129	180 (aa)	-	A0A0A0MRR7
ENST00000244520	SNRPC-201	842	-	ENSP00000244520	159 (aa)	-	P09234
ENST00000474635	SNRPC-204	511	-	-	- (aa)	-	-
ENST00000374018	SNRPC-203	600	-	ENSP00000363130	118 (aa)	-	Q5TAL2

Gene Model

Click here to download ENSG00000124562's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000124562	rs75398113	6	34760294	C	Obese vs. thin	30677029	[1.19-1.42]	1.3	EFO_0007041

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124562's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124562	SNRPC	100	100.000	ENSAMEG00000000963	SNRPC	100	95.028	Ailuropoda_melanoleuca
ENSG00000124562	SNRPC	100	96.610	ENSACAG00000015721	SNRPC	99	89.385	Anolis_carolinensis
ENSG00000124562	SNRPC	100	99.371	ENSANAG00000007843	-	100	99.371	Aotus_nancymaae
ENSG00000124562	SNRPC	100	93.220	ENSANAG00000021026	-	100	80.503	Aotus_nancymaae
ENSG00000124562	SNRPC	100	92.373	ENSANAG00000020588	-	92	91.772	Aotus_nancymaae
ENSG00000124562	SNRPC	100	89.308	ENSANAG00000019726	-	100	84.884	Aotus_nancymaae
ENSG00000124562	SNRPC	100	76.101	ENSANAG00000021444	-	61	83.333	Aotus_nancymaae
ENSG00000124562	SNRPC	100	100.000	ENSANAG00000019696	-	100	100.000	Aotus_nancymaae
ENSG00000124562	SNRPC	100	95.763	ENSANAG00000019157	-	100	95.597	Aotus_nancymaae
ENSG00000124562	SNRPC	100	84.906	ENSAMXG00000032641	snrpc	100	72.956	Astyanax_mexicanus
ENSG00000124562	SNRPC	100	100.000	ENSBTAG00000024549	SNRPC	100	100.000	Bos_taurus
ENSG00000124562	SNRPC	100	98.742	ENSCJAG00000043055	-	100	98.742	Callithrix_jacchus
ENSG00000124562	SNRPC	100	100.000	ENSCJAG00000015321	-	100	100.000	Callithrix_jacchus
ENSG00000124562	SNRPC	100	97.484	ENSCJAG00000041822	-	100	97.484	Callithrix_jacchus
ENSG00000124562	SNRPC	100	78.616	ENSCAFG00000025525	-	100	78.616	Canis_familiaris
ENSG00000124562	SNRPC	74	100.000	ENSCAFG00000001231	-	93	100.000	Canis_familiaris
ENSG00000124562	SNRPC	100	95.597	ENSCAFG00000031775	-	100	95.597	Canis_familiaris
ENSG00000124562	SNRPC	100	97.500	ENSCAFG00000028988	-	100	97.500	Canis_familiaris
ENSG00000124562	SNRPC	100	80.292	ENSCAFG00020026577	-	100	84.831	Canis_lupus_dingo
ENSG00000124562	SNRPC	100	95.597	ENSCAFG00020017383	-	100	95.597	Canis_lupus_dingo
ENSG00000124562	SNRPC	100	100.000	ENSCAFG00020005945	-	100	100.000	Canis_lupus_dingo
ENSG00000124562	SNRPC	100	96.610	ENSCAFG00020005758	-	100	96.226	Canis_lupus_dingo
ENSG00000124562	SNRPC	100	88.136	ENSCAFG00020009944	-	90	88.535	Canis_lupus_dingo
ENSG00000124562	SNRPC	100	72.327	ENSCHIG00000005039	-	100	71.069	Capra_hircus
ENSG00000124562	SNRPC	100	100.000	ENSCHIG00000012087	-	100	99.371	Capra_hircus
ENSG00000124562	SNRPC	100	100.000	ENSTSYG00000011216	-	100	100.000	Carlito_syrichta
ENSG00000124562	SNRPC	99	89.241	ENSTSYG00000029745	-	62	94.309	Carlito_syrichta
ENSG00000124562	SNRPC	100	83.019	ENSTSYG00000025721	-	100	76.101	Carlito_syrichta
ENSG00000124562	SNRPC	100	100.000	ENSCAPG00000005161	SNRPC	100	100.000	Cavia_aperea
ENSG00000124562	SNRPC	100	100.000	ENSCPOG00000008563	SNRPC	100	100.000	Cavia_porcellus
ENSG00000124562	SNRPC	100	69.811	ENSCCAG00000028293	-	63	86.585	Cebus_capucinus
ENSG00000124562	SNRPC	100	91.525	ENSCCAG00000022751	-	97	90.566	Cebus_capucinus
ENSG00000124562	SNRPC	95	96.429	ENSCCAG00000022209	-	95	80.128	Cebus_capucinus
ENSG00000124562	SNRPC	99	81.529	ENSCCAG00000026624	-	66	75.796	Cebus_capucinus
ENSG00000124562	SNRPC	100	94.340	ENSCCAG00000036059	-	89	94.340	Cebus_capucinus
ENSG00000124562	SNRPC	100	100.000	ENSCATG00000035787	SNRPC	100	100.000	Cercocebus_atys
ENSG00000124562	SNRPC	100	100.000	ENSCLAG00000016920	SNRPC	100	100.000	Chinchilla_lanigera
ENSG00000124562	SNRPC	99	81.529	ENSCLAG00000010242	-	96	82.051	Chinchilla_lanigera
ENSG00000124562	SNRPC	100	89.326	ENSCSAG00000009821	SNRPC	100	89.326	Chlorocebus_sabaeus
ENSG00000124562	SNRPC	100	81.132	ENSCHOG00000011439	SNRPC	100	77.778	Choloepus_hoffmanni
ENSG00000124562	SNRPC	100	97.484	ENSCPBG00000027142	SNRPC	100	97.484	Chrysemys_picta_bellii
ENSG00000124562	SNRPC	97	49.351	ENSCING00000021229	ci-zf(matrin)-4	51	85.484	Ciona_intestinalis
ENSG00000124562	SNRPC	100	100.000	ENSCANG00000028035	SNRPC	100	100.000	Colobus_angolensis_palliatus
ENSG00000124562	SNRPC	100	87.421	ENSCGRG00001021483	-	100	85.535	Cricetulus_griseus_chok1gshd
ENSG00000124562	SNRPC	100	99.371	ENSCGRG00001009011	-	100	99.371	Cricetulus_griseus_chok1gshd
ENSG00000124562	SNRPC	100	99.153	ENSCGRG00000005005	Snrpc	100	98.742	Cricetulus_griseus_crigri
ENSG00000124562	SNRPC	100	84.906	ENSDARG00000009871	snrpc	100	84.906	Danio_rerio
ENSG00000124562	SNRPC	100	99.153	ENSDNOG00000034699	-	99	98.742	Dasypus_novemcinctus
ENSG00000124562	SNRPC	75	99.160	ENSDNOG00000042403	-	94	99.160	Dasypus_novemcinctus
ENSG00000124562	SNRPC	100	81.132	ENSDORG00000005955	Snrpc	75	76.536	Dipodomys_ordii
ENSG00000124562	SNRPC	95	79.470	ENSDORG00000029823	-	56	96.104	Dipodomys_ordii
ENSG00000124562	SNRPC	98	92.308	ENSETEG00000011265	-	100	92.308	Echinops_telfairi
ENSG00000124562	SNRPC	52	95.181	ENSETEG00000008756	-	94	83.838	Echinops_telfairi
ENSG00000124562	SNRPC	98	96.154	ENSETEG00000008268	-	100	96.154	Echinops_telfairi
ENSG00000124562	SNRPC	100	100.000	ENSEASG00005021007	SNRPC	100	100.000	Equus_asinus_asinus
ENSG00000124562	SNRPC	100	100.000	ENSECAG00000026848	SNRPC	100	100.000	Equus_caballus
ENSG00000124562	SNRPC	99	79.747	ENSEEUG00000014633	SNRPC	100	76.111	Erinaceus_europaeus
ENSG00000124562	SNRPC	100	78.616	ENSELUG00000000815	SNRPC	50	94.872	Esox_lucius
ENSG00000124562	SNRPC	100	100.000	ENSFCAG00000044077	-	100	100.000	Felis_catus
ENSG00000124562	SNRPC	100	93.082	ENSFCAG00000031775	-	100	83.889	Felis_catus
ENSG00000124562	SNRPC	100	98.742	ENSFALG00000003756	SNRPC	100	98.742	Ficedula_albicollis
ENSG00000124562	SNRPC	100	100.000	ENSFDAG00000018111	SNRPC	100	100.000	Fukomys_damarensis
ENSG00000124562	SNRPC	100	96.875	ENSGALG00000002773	SNRPC	100	96.875	Gallus_gallus
ENSG00000124562	SNRPC	100	97.484	ENSGAGG00000003063	SNRPC	100	97.484	Gopherus_agassizii
ENSG00000124562	SNRPC	100	100.000	ENSGGOG00000012499	SNRPC	100	100.000	Gorilla_gorilla
ENSG00000124562	SNRPC	100	81.132	ENSHGLG00000017741	-	100	78.616	Heterocephalus_glaber_female
ENSG00000124562	SNRPC	81	75.194	ENSHGLG00000005871	-	100	75.472	Heterocephalus_glaber_female
ENSG00000124562	SNRPC	100	100.000	ENSHGLG00000013981	SNRPC	100	100.000	Heterocephalus_glaber_female
ENSG00000124562	SNRPC	100	94.969	ENSHGLG00100017764	-	100	94.969	Heterocephalus_glaber_male
ENSG00000124562	SNRPC	100	100.000	ENSHGLG00100009478	SNRPC	100	100.000	Heterocephalus_glaber_male
ENSG00000124562	SNRPC	100	81.132	ENSHGLG00100010786	-	100	78.616	Heterocephalus_glaber_male
ENSG00000124562	SNRPC	100	85.535	ENSIPUG00000024851	snrpc	100	85.535	Ictalurus_punctatus
ENSG00000124562	SNRPC	100	100.000	ENSSTOG00000013786	SNRPC	100	100.000	Ictidomys_tridecemlineatus
ENSG00000124562	SNRPC	100	99.371	ENSJJAG00000021741	Snrpc	100	99.371	Jaculus_jaculus
ENSG00000124562	SNRPC	100	88.125	ENSLACG00000013753	SNRPC	89	90.625	Latimeria_chalumnae
ENSG00000124562	SNRPC	100	100.000	ENSLAFG00000013534	SNRPC	100	100.000	Loxodonta_africana
ENSG00000124562	SNRPC	100	100.000	ENSMFAG00000031764	-	100	100.000	Macaca_fascicularis
ENSG00000124562	SNRPC	100	99.371	ENSMFAG00000030525	-	100	99.371	Macaca_fascicularis
ENSG00000124562	SNRPC	100	100.000	ENSMMUG00000000869	-	97	98.742	Macaca_mulatta
ENSG00000124562	SNRPC	100	89.937	ENSMMUG00000045425	-	100	89.937	Macaca_mulatta
ENSG00000124562	SNRPC	100	99.153	ENSMMUG00000039415	-	100	98.742	Macaca_mulatta
ENSG00000124562	SNRPC	100	100.000	ENSMNEG00000032731	SNRPC	100	100.000	Macaca_nemestrina
ENSG00000124562	SNRPC	100	100.000	ENSMLEG00000033916	-	100	100.000	Mandrillus_leucophaeus
ENSG00000124562	SNRPC	100	88.983	ENSMLEG00000040224	-	99	85.632	Mandrillus_leucophaeus
ENSG00000124562	SNRPC	100	96.855	ENSMGAG00000006054	SNRPC	100	96.855	Meleagris_gallopavo
ENSG00000124562	SNRPC	100	99.371	ENSMICG00000007339	-	100	99.371	Microcebus_murinus
ENSG00000124562	SNRPC	100	88.050	ENSMICG00000009130	-	100	88.679	Microcebus_murinus
ENSG00000124562	SNRPC	100	99.371	ENSMICG00000032183	-	100	99.371	Microcebus_murinus
ENSG00000124562	SNRPC	100	84.906	ENSMICG00000036552	-	93	77.976	Microcebus_murinus
ENSG00000124562	SNRPC	100	99.371	ENSMOCG00000017609	Snrpc	100	99.371	Microtus_ochrogaster
ENSG00000124562	SNRPC	100	65.254	ENSMODG00000025263	-	100	73.585	Monodelphis_domestica
ENSG00000124562	SNRPC	100	98.742	ENSMODG00000013904	-	100	98.742	Monodelphis_domestica
ENSG00000124562	SNRPC	100	66.667	ENSMALG00000001197	snrpc	100	65.244	Monopterus_albus
ENSG00000124562	SNRPC	100	99.371	MGP_CAROLIEiJ_G0021308	Snrpc	100	99.371	Mus_caroli
ENSG00000124562	SNRPC	100	99.371	ENSMUSG00000024217	Snrpc	100	99.371	Mus_musculus
ENSG00000124562	SNRPC	74	99.153	MGP_SPRETEiJ_G0022221	-	98	99.153	Mus_spretus
ENSG00000124562	SNRPC	100	100.000	ENSMPUG00000003210	SNRPC	100	99.371	Mustela_putorius_furo
ENSG00000124562	SNRPC	100	100.000	ENSMLUG00000002488	SNRPC	100	99.371	Myotis_lucifugus
ENSG00000124562	SNRPC	100	99.371	ENSNGAG00000019686	Snrpc	100	99.371	Nannospalax_galili
ENSG00000124562	SNRPC	100	100.000	ENSNLEG00000034810	SNRPC	100	100.000	Nomascus_leucogenys
ENSG00000124562	SNRPC	100	99.153	ENSMEUG00000009300	SNRPC	100	99.296	Notamacropus_eugenii
ENSG00000124562	SNRPC	100	99.371	ENSODEG00000020201	-	100	99.371	Octodon_degus
ENSG00000124562	SNRPC	100	100.000	ENSODEG00000020370	-	100	100.000	Octodon_degus
ENSG00000124562	SNRPC	100	100.000	ENSODEG00000017080	-	100	100.000	Octodon_degus
ENSG00000124562	SNRPC	100	100.000	ENSODEG00000018985	-	100	100.000	Octodon_degus
ENSG00000124562	SNRPC	77	94.309	ENSODEG00000006008	-	88	94.309	Octodon_degus
ENSG00000124562	SNRPC	100	99.153	ENSODEG00000019633	-	100	98.742	Octodon_degus
ENSG00000124562	SNRPC	100	95.902	ENSOANG00000003405	SNRPC	100	95.270	Ornithorhynchus_anatinus
ENSG00000124562	SNRPC	100	100.000	ENSOCUG00000026668	-	100	100.000	Oryctolagus_cuniculus
ENSG00000124562	SNRPC	100	98.742	ENSOCUG00000026430	-	99	98.742	Oryctolagus_cuniculus
ENSG00000124562	SNRPC	100	97.484	ENSOCUG00000023292	-	100	97.484	Oryctolagus_cuniculus
ENSG00000124562	SNRPC	97	85.088	ENSOGAG00000028405	-	99	81.818	Otolemur_garnettii
ENSG00000124562	SNRPC	100	100.000	ENSOGAG00000008755	-	100	94.444	Otolemur_garnettii
ENSG00000124562	SNRPC	100	98.305	ENSOGAG00000026269	-	100	98.113	Otolemur_garnettii
ENSG00000124562	SNRPC	100	100.000	ENSOARG00000010823	SNRPC	100	100.000	Ovis_aries
ENSG00000124562	SNRPC	100	100.000	ENSPPAG00000043871	SNRPC	100	100.000	Pan_paniscus
ENSG00000124562	SNRPC	96	60.390	ENSPPRG00000016017	-	86	54.902	Panthera_pardus
ENSG00000124562	SNRPC	100	100.000	ENSPPRG00000008647	-	100	100.000	Panthera_pardus
ENSG00000124562	SNRPC	100	100.000	ENSPTIG00000021867	-	100	100.000	Panthera_tigris_altaica
ENSG00000124562	SNRPC	97	60.000	ENSPTIG00000013329	-	50	83.117	Panthera_tigris_altaica
ENSG00000124562	SNRPC	100	100.000	ENSPTRG00000018070	SNRPC	100	100.000	Pan_troglodytes
ENSG00000124562	SNRPC	100	100.000	ENSPANG00000022802	-	100	100.000	Papio_anubis
ENSG00000124562	SNRPC	100	88.983	ENSPANG00000018228	-	94	88.679	Papio_anubis
ENSG00000124562	SNRPC	100	95.763	ENSPSIG00000004876	SNRPC	77	96.815	Pelodiscus_sinensis
ENSG00000124562	SNRPC	100	99.371	ENSPEMG00000010773	Snrpc	100	99.371	Peromyscus_maniculatus_bairdii
ENSG00000124562	SNRPC	100	87.421	ENSPEMG00000002763	-	100	85.535	Peromyscus_maniculatus_bairdii
ENSG00000124562	SNRPC	52	100.000	ENSPPYG00000029902	-	84	100.000	Pongo_abelii
ENSG00000124562	SNRPC	100	100.000	ENSPCAG00000016885	SNRPC	100	91.667	Procavia_capensis
ENSG00000124562	SNRPC	100	100.000	ENSPCOG00000004904	SNRPC	100	100.000	Propithecus_coquereli
ENSG00000124562	SNRPC	100	100.000	ENSPVAG00000015597	SNRPC	100	93.923	Pteropus_vampyrus
ENSG00000124562	SNRPC	100	99.371	ENSRNOG00000000493	Snrpc	100	99.371	Rattus_norvegicus
ENSG00000124562	SNRPC	100	99.371	ENSRBIG00000022998	-	100	99.371	Rhinopithecus_bieti
ENSG00000124562	SNRPC	100	99.371	ENSRBIG00000014819	-	100	99.371	Rhinopithecus_bieti
ENSG00000124562	SNRPC	100	100.000	ENSRBIG00000037567	-	100	100.000	Rhinopithecus_bieti
ENSG00000124562	SNRPC	100	89.308	ENSRBIG00000036353	-	91	84.483	Rhinopithecus_bieti
ENSG00000124562	SNRPC	100	100.000	ENSRROG00000041300	SNRPC	100	100.000	Rhinopithecus_roxellana
ENSG00000124562	SNRPC	100	100.000	ENSSBOG00000031528	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000124562	SNRPC	95	82.781	ENSSBOG00000032361	-	66	81.250	Saimiri_boliviensis_boliviensis
ENSG00000124562	SNRPC	98	82.692	ENSSBOG00000023189	-	91	82.692	Saimiri_boliviensis_boliviensis
ENSG00000124562	SNRPC	98	81.410	ENSSBOG00000032882	-	95	80.380	Saimiri_boliviensis_boliviensis
ENSG00000124562	SNRPC	100	65.254	ENSSHAG00000002972	-	100	75.472	Sarcophilus_harrisii
ENSG00000124562	SNRPC	100	99.153	ENSSHAG00000000945	-	96	94.186	Sarcophilus_harrisii
ENSG00000124562	SNRPC	100	81.132	ENSSFOG00015019150	snrpc	100	81.132	Scleropages_formosus
ENSG00000124562	SNRPC	100	76.101	ENSSARG00000008970	SNRPC	96	75.439	Sorex_araneus
ENSG00000124562	SNRPC	100	98.113	ENSSPUG00000002502	SNRPC	100	98.113	Sphenodon_punctatus
ENSG00000124562	SNRPC	100	100.000	ENSSSCG00000001531	SNRPC	100	100.000	Sus_scrofa
ENSG00000124562	SNRPC	100	98.305	ENSTGUG00000001773	SNRPC	99	98.726	Taeniopygia_guttata
ENSG00000124562	SNRPC	98	92.308	ENSTBEG00000013022	-	100	92.308	Tupaia_belangeri
ENSG00000124562	SNRPC	98	73.718	ENSTBEG00000015356	-	68	91.667	Tupaia_belangeri
ENSG00000124562	SNRPC	100	66.949	ENSTBEG00000016759	-	79	72.535	Tupaia_belangeri
ENSG00000124562	SNRPC	100	100.000	ENSTTRG00000007827	SNRPC	100	93.956	Tursiops_truncatus
ENSG00000124562	SNRPC	75	99.160	ENSUAMG00000014125	SNRPC	80	99.160	Ursus_americanus
ENSG00000124562	SNRPC	100	89.326	ENSUMAG00000010869	SNRPC	100	89.326	Ursus_maritimus
ENSG00000124562	SNRPC	100	69.492	ENSVPAG00000003106	SNRPC	100	63.889	Vicugna_pacos
ENSG00000124562	SNRPC	100	93.220	ENSVVUG00000010467	-	95	89.535	Vulpes_vulpes
ENSG00000124562	SNRPC	100	100.000	ENSVVUG00000021947	-	100	98.742	Vulpes_vulpes
ENSG00000124562	SNRPC	100	89.937	ENSXETG00000024721	snrpc	100	89.937	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000243	commitment complex	-	IEA	Component
GO:0000387	spliceosomal snRNP assembly	8972845.	IDA	Process
GO:0000395	mRNA 5'-splice site recognition	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	8972845.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003727	single-stranded RNA binding	8798632.	IDA	Function
GO:0003729	mRNA binding	-	IEA	Function
GO:0005515	protein binding	8076607.12486009.22365833.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005685	U1 snRNP	21873635.	IBA	Component
GO:0005685	U1 snRNP	15312772.15525645.21113136.	IDA	Component
GO:0008270	zinc ion binding	15312772.	IDA	Function
GO:0015030	Cajal body	10068039.	IDA	Component
GO:0030619	U1 snRNA binding	1826349.	IDA	Function
GO:0030627	pre-mRNA 5'-splice site binding	21873635.	IBA	Function
GO:0042803	protein homodimerization activity	8532530.	IPI	Function
GO:0071004	U2-type prespliceosome	-	IEA	Component
GO:1990446	U1 snRNP binding	-	IEA	Function