EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000124713 (Gene tree)
Gene ID: 27232
Gene Symbol: GNMT
Alias: -
Full Name: glycine N-methyltransferase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 24,466 bases
Position: chr6:42,939,415-42,963,880
Accession: 4415
RBP type: canonical RBP
Summary: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000361894	Methyltransf_31	PF13847.6	1.3e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000372808	GNMT-201	1072	-	ENSP00000361894	295 (aa)	-	Q14749

Gene Model

Click here to download ENSG00000124713's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00260	Glycine, serine and threonine metabolism	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000124713's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000124713	GNMT	99	74.403	ENSAPOG00000019561	gnmt	99	74.403	Acanthochromis_polyacanthus
ENSG00000124713	GNMT	100	94.576	ENSAMEG00000012753	GNMT	100	94.576	Ailuropoda_melanoleuca
ENSG00000124713	GNMT	99	74.315	ENSACIG00000003441	gnmt	99	74.315	Amphilophus_citrinellus
ENSG00000124713	GNMT	99	74.744	ENSAOCG00000006298	gnmt	99	74.744	Amphiprion_ocellaris
ENSG00000124713	GNMT	99	74.744	ENSAPEG00000018396	gnmt	99	74.744	Amphiprion_percula
ENSG00000124713	GNMT	99	73.720	ENSATEG00000008278	gnmt	97	73.720	Anabas_testudineus
ENSG00000124713	GNMT	99	79.932	ENSACAG00000005587	GNMT	99	79.932	Anolis_carolinensis
ENSG00000124713	GNMT	100	96.949	ENSANAG00000021291	GNMT	100	96.949	Aotus_nancymaae
ENSG00000124713	GNMT	99	73.630	ENSACLG00000020588	gnmt	99	73.630	Astatotilapia_calliptera
ENSG00000124713	GNMT	93	73.188	ENSAMXG00000042907	gnmt	99	73.188	Astyanax_mexicanus
ENSG00000124713	GNMT	99	92.517	ENSBTAG00000051409	-	99	92.517	Bos_taurus
ENSG00000124713	GNMT	99	92.857	ENSBTAG00000051534	GNMT	99	92.857	Bos_taurus
ENSG00000124713	GNMT	100	96.949	ENSCJAG00000004675	GNMT	100	96.949	Callithrix_jacchus
ENSG00000124713	GNMT	90	89.850	ENSCAFG00000001741	GNMT	78	89.850	Canis_familiaris
ENSG00000124713	GNMT	100	96.271	ENSCAFG00020010607	GNMT	100	96.271	Canis_lupus_dingo
ENSG00000124713	GNMT	99	93.857	ENSCHIG00000026364	GNMT	99	93.857	Capra_hircus
ENSG00000124713	GNMT	99	89.761	ENSCPOG00000033341	GNMT	99	89.761	Cavia_porcellus
ENSG00000124713	GNMT	100	96.610	ENSCCAG00000035170	GNMT	100	96.610	Cebus_capucinus
ENSG00000124713	GNMT	100	98.644	ENSCATG00000032921	GNMT	100	98.644	Cercocebus_atys
ENSG00000124713	GNMT	100	91.864	ENSCLAG00000013521	GNMT	100	91.864	Chinchilla_lanigera
ENSG00000124713	GNMT	100	98.644	ENSCSAG00000011512	GNMT	100	98.644	Chlorocebus_sabaeus
ENSG00000124713	GNMT	92	73.723	ENSCPBG00000003801	-	96	73.723	Chrysemys_picta_bellii
ENSG00000124713	GNMT	100	97.966	ENSCANG00000034169	GNMT	100	97.966	Colobus_angolensis_palliatus
ENSG00000124713	GNMT	100	93.559	ENSCGRG00001020404	Gnmt	100	93.559	Cricetulus_griseus_chok1gshd
ENSG00000124713	GNMT	100	93.559	ENSCGRG00000015089	Gnmt	100	93.559	Cricetulus_griseus_crigri
ENSG00000124713	GNMT	99	73.038	ENSCSEG00000000109	gnmt	99	73.038	Cynoglossus_semilaevis
ENSG00000124713	GNMT	99	72.696	ENSCVAG00000009951	gnmt	99	72.696	Cyprinodon_variegatus
ENSG00000124713	GNMT	99	72.542	ENSDARG00000006840	gnmt	99	72.542	Danio_rerio
ENSG00000124713	GNMT	99	57.045	FBgn0038074	Gnmt	97	57.045	Drosophila_melanogaster
ENSG00000124713	GNMT	93	41.304	ENSEBUG00000007574	-	98	41.304	Eptatretus_burgeri
ENSG00000124713	GNMT	99	67.628	ENSEBUG00000011858	gnmt	99	67.628	Eptatretus_burgeri
ENSG00000124713	GNMT	93	44.364	ENSEBUG00000013162	-	99	44.364	Eptatretus_burgeri
ENSG00000124713	GNMT	100	94.915	ENSEASG00005003124	GNMT	100	94.915	Equus_asinus_asinus
ENSG00000124713	GNMT	100	95.254	ENSECAG00000017768	GNMT	100	95.254	Equus_caballus
ENSG00000124713	GNMT	96	74.205	ENSELUG00000019811	gnmt	93	74.205	Esox_lucius
ENSG00000124713	GNMT	100	95.932	ENSFCAG00000009711	GNMT	100	95.932	Felis_catus
ENSG00000124713	GNMT	89	77.947	ENSFALG00000000732	GNMT	99	77.947	Ficedula_albicollis
ENSG00000124713	GNMT	100	91.864	ENSFDAG00000020423	GNMT	100	91.864	Fukomys_damarensis
ENSG00000124713	GNMT	99	70.608	ENSGMOG00000010882	gnmt	99	70.608	Gadus_morhua
ENSG00000124713	GNMT	52	82.237	ENSGALG00000043290	-	88	82.237	Gallus_gallus
ENSG00000124713	GNMT	99	73.720	ENSGAFG00000001478	gnmt	99	73.720	Gambusia_affinis
ENSG00000124713	GNMT	99	71.672	ENSGACG00000005698	gnmt	98	71.672	Gasterosteus_aculeatus
ENSG00000124713	GNMT	79	82.479	ENSGAGG00000025685	GNMT	99	82.479	Gopherus_agassizii
ENSG00000124713	GNMT	100	100.000	ENSGGOG00000013572	GNMT	100	100.000	Gorilla_gorilla
ENSG00000124713	GNMT	99	73.973	ENSHBUG00000020847	gnmt	99	73.973	Haplochromis_burtoni
ENSG00000124713	GNMT	100	91.525	ENSHGLG00000017376	GNMT	100	91.525	Heterocephalus_glaber_female
ENSG00000124713	GNMT	100	91.186	ENSHGLG00100006220	GNMT	100	91.186	Heterocephalus_glaber_male
ENSG00000124713	GNMT	99	72.696	ENSHCOG00000014727	gnmt	99	72.696	Hippocampus_comes
ENSG00000124713	GNMT	99	70.169	ENSIPUG00000009695	Gnmt	99	70.169	Ictalurus_punctatus
ENSG00000124713	GNMT	100	93.559	ENSSTOG00000009464	GNMT	100	93.559	Ictidomys_tridecemlineatus
ENSG00000124713	GNMT	52	95.395	ENSJJAG00000001038	-	92	95.395	Jaculus_jaculus
ENSG00000124713	GNMT	99	75.427	ENSKMAG00000010405	gnmt	99	75.427	Kryptolebias_marmoratus
ENSG00000124713	GNMT	99	73.379	ENSLBEG00000019748	gnmt	99	73.379	Labrus_bergylta
ENSG00000124713	GNMT	99	77.211	ENSLACG00000008668	GNMT	99	77.211	Latimeria_chalumnae
ENSG00000124713	GNMT	99	75.932	ENSLOCG00000017179	gnmt	99	76.271	Lepisosteus_oculatus
ENSG00000124713	GNMT	100	92.905	ENSLAFG00000013861	GNMT	100	92.905	Loxodonta_africana
ENSG00000124713	GNMT	100	98.644	ENSMFAG00000045063	GNMT	100	98.644	Macaca_fascicularis
ENSG00000124713	GNMT	100	98.644	ENSMMUG00000001393	GNMT	100	98.644	Macaca_mulatta
ENSG00000124713	GNMT	100	98.644	ENSMNEG00000036639	GNMT	100	98.644	Macaca_nemestrina
ENSG00000124713	GNMT	100	98.644	ENSMLEG00000035798	GNMT	100	98.644	Mandrillus_leucophaeus
ENSG00000124713	GNMT	99	73.973	ENSMZEG00005006910	gnmt	99	73.973	Maylandia_zebra
ENSG00000124713	GNMT	96	80.919	ENSMGAG00000007120	GNMT	99	80.919	Meleagris_gallopavo
ENSG00000124713	GNMT	69	94.702	ENSMAUG00000016515	Gnmt	72	94.702	Mesocricetus_auratus
ENSG00000124713	GNMT	100	94.237	ENSMICG00000008225	GNMT	100	94.237	Microcebus_murinus
ENSG00000124713	GNMT	99	73.379	ENSMMOG00000002466	gnmt	99	73.379	Mola_mola
ENSG00000124713	GNMT	98	89.583	ENSMODG00000019018	GNMT	98	89.583	Monodelphis_domestica
ENSG00000124713	GNMT	99	72.696	ENSMALG00000010637	gnmt	99	72.696	Monopterus_albus
ENSG00000124713	GNMT	100	92.203	MGP_CAROLIEiJ_G0021685	Gnmt	100	92.203	Mus_caroli
ENSG00000124713	GNMT	100	91.525	ENSMUSG00000002769	Gnmt	100	91.525	Mus_musculus
ENSG00000124713	GNMT	100	92.542	MGP_PahariEiJ_G0020676	Gnmt	100	92.542	Mus_pahari
ENSG00000124713	GNMT	100	91.864	MGP_SPRETEiJ_G0022597	Gnmt	100	91.864	Mus_spretus
ENSG00000124713	GNMT	100	96.271	ENSMLUG00000012100	GNMT	100	96.271	Myotis_lucifugus
ENSG00000124713	GNMT	52	95.395	ENSNGAG00000013438	-	84	95.395	Nannospalax_galili
ENSG00000124713	GNMT	99	73.288	ENSNBRG00000010043	gnmt	99	73.288	Neolamprologus_brichardi
ENSG00000124713	GNMT	100	98.644	ENSNLEG00000030090	GNMT	100	98.644	Nomascus_leucogenys
ENSG00000124713	GNMT	99	91.156	ENSMEUG00000007821	GNMT	99	91.156	Notamacropus_eugenii
ENSG00000124713	GNMT	99	72.603	ENSONIG00000008264	gnmt	99	72.603	Oreochromis_niloticus
ENSG00000124713	GNMT	99	94.218	ENSOCUG00000003858	GNMT	99	94.218	Oryctolagus_cuniculus
ENSG00000124713	GNMT	99	73.288	ENSORLG00000023048	gnmt	99	73.288	Oryzias_latipes
ENSG00000124713	GNMT	99	73.288	ENSORLG00020017645	gnmt	99	73.288	Oryzias_latipes_hni
ENSG00000124713	GNMT	99	72.945	ENSORLG00015014146	gnmt	99	72.945	Oryzias_latipes_hsok
ENSG00000124713	GNMT	99	73.379	ENSOMEG00000012757	gnmt	99	73.379	Oryzias_melastigma
ENSG00000124713	GNMT	100	95.254	ENSOGAG00000012676	GNMT	100	95.254	Otolemur_garnettii
ENSG00000124713	GNMT	99	93.174	ENSOARG00000004327	GNMT	95	93.174	Ovis_aries
ENSG00000124713	GNMT	100	100.000	ENSPPAG00000000924	GNMT	100	100.000	Pan_paniscus
ENSG00000124713	GNMT	100	95.593	ENSPPRG00000023762	GNMT	100	95.593	Panthera_pardus
ENSG00000124713	GNMT	100	95.593	ENSPTIG00000021496	GNMT	100	95.593	Panthera_tigris_altaica
ENSG00000124713	GNMT	100	100.000	ENSPTRG00000018178	GNMT	100	100.000	Pan_troglodytes
ENSG00000124713	GNMT	100	98.305	ENSPANG00000022693	GNMT	100	98.305	Papio_anubis
ENSG00000124713	GNMT	99	77.627	ENSPKIG00000022265	gnmt	91	82.143	Paramormyrops_kingsleyae
ENSG00000124713	GNMT	77	68.860	ENSPSIG00000002397	GNMT	99	68.860	Pelodiscus_sinensis
ENSG00000124713	GNMT	99	75.085	ENSPMGG00000008397	gnmt	99	75.085	Periophthalmus_magnuspinnatus
ENSG00000124713	GNMT	99	92.177	ENSPEMG00000011330	Gnmt	99	92.177	Peromyscus_maniculatus_bairdii
ENSG00000124713	GNMT	99	90.816	ENSPCIG00000009285	GNMT	99	90.816	Phascolarctos_cinereus
ENSG00000124713	GNMT	99	72.696	ENSPFOG00000010483	gnmt	99	72.696	Poecilia_formosa
ENSG00000124713	GNMT	99	72.696	ENSPLAG00000007172	gnmt	99	72.696	Poecilia_latipinna
ENSG00000124713	GNMT	99	72.696	ENSPMEG00000024025	gnmt	99	72.696	Poecilia_mexicana
ENSG00000124713	GNMT	67	88.500	ENSPPYG00000016623	-	100	88.500	Pongo_abelii
ENSG00000124713	GNMT	100	93.898	ENSPCOG00000020942	GNMT	100	93.898	Propithecus_coquereli
ENSG00000124713	GNMT	100	89.831	ENSPVAG00000008702	GNMT	100	89.831	Pteropus_vampyrus
ENSG00000124713	GNMT	88	71.429	ENSPNYG00000004219	gnmt	88	73.790	Pundamilia_nyererei
ENSG00000124713	GNMT	99	72.881	ENSPNAG00000001905	gnmt	99	72.881	Pygocentrus_nattereri
ENSG00000124713	GNMT	99	91.156	ENSRNOG00000048623	LOC100911564	99	91.156	Rattus_norvegicus
ENSG00000124713	GNMT	99	92.177	ENSRNOG00000016349	Gnmt	99	92.177	Rattus_norvegicus
ENSG00000124713	GNMT	100	97.627	ENSRBIG00000044856	GNMT	100	97.627	Rhinopithecus_bieti
ENSG00000124713	GNMT	100	97.627	ENSRROG00000042667	GNMT	100	97.627	Rhinopithecus_roxellana
ENSG00000124713	GNMT	100	96.949	ENSSBOG00000023382	GNMT	100	96.949	Saimiri_boliviensis_boliviensis
ENSG00000124713	GNMT	99	91.156	ENSSHAG00000011595	GNMT	99	91.156	Sarcophilus_harrisii
ENSG00000124713	GNMT	99	62.626	ENSSFOG00015004123	gnmt	99	62.626	Scleropages_formosus
ENSG00000124713	GNMT	99	74.315	ENSSDUG00000013522	gnmt	99	74.315	Seriola_dumerili
ENSG00000124713	GNMT	99	73.630	ENSSLDG00000017480	gnmt	99	73.630	Seriola_lalandi_dorsalis
ENSG00000124713	GNMT	99	83.333	ENSSPUG00000018643	GNMT	99	83.333	Sphenodon_punctatus
ENSG00000124713	GNMT	99	73.379	ENSSPAG00000006015	gnmt	99	73.379	Stegastes_partitus
ENSG00000124713	GNMT	100	94.576	ENSSSCG00000033214	GNMT	96	94.576	Sus_scrofa
ENSG00000124713	GNMT	72	78.873	ENSTGUG00000005210	GNMT	99	78.873	Taeniopygia_guttata
ENSG00000124713	GNMT	51	79.333	ENSTRUG00000000840	gnmt	99	79.333	Takifugu_rubripes
ENSG00000124713	GNMT	99	72.449	ENSTNIG00000008896	gnmt	99	72.449	Tetraodon_nigroviridis
ENSG00000124713	GNMT	100	94.576	ENSTTRG00000006983	GNMT	100	94.576	Tursiops_truncatus
ENSG00000124713	GNMT	100	95.932	ENSUAMG00000017465	GNMT	100	95.932	Ursus_americanus
ENSG00000124713	GNMT	100	96.271	ENSVVUG00000027542	GNMT	100	96.271	Vulpes_vulpes
ENSG00000124713	GNMT	51	76.000	ENSXCOG00000013186	gnmt	94	76.000	Xiphophorus_couchianus
ENSG00000124713	GNMT	99	71.331	ENSXMAG00000000189	gnmt	99	71.331	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16189514.21988832.26871637.	IPI	Function
GO:0005542	folic acid binding	-	IEA	Function
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005977	glycogen metabolic process	-	IEA	Process
GO:0006111	regulation of gluconeogenesis	21873635.	IBA	Process
GO:0006464	cellular protein modification process	10843803.	NAS	Process
GO:0006555	methionine metabolic process	-	IEA	Process
GO:0006730	one-carbon metabolic process	21873635.	IBA	Process
GO:0016594	glycine binding	21873635.	IBA	Function
GO:0016594	glycine binding	15340920.	IDA	Function
GO:0017174	glycine N-methyltransferase activity	21873635.	IBA	Function
GO:0017174	glycine N-methyltransferase activity	15340920.	IDA	Function
GO:0032259	methylation	-	IEA	Process
GO:0034641	cellular nitrogen compound metabolic process	-	TAS	Process
GO:0042802	identical protein binding	21873635.	IBA	Function
GO:0042802	identical protein binding	16189514.26871637.	IPI	Function
GO:0046498	S-adenosylhomocysteine metabolic process	21873635.	IBA	Process
GO:0046500	S-adenosylmethionine metabolic process	21873635.	IBA	Process
GO:0046500	S-adenosylmethionine metabolic process	15340920.	IDA	Process
GO:0051289	protein homotetramerization	21873635.	IBA	Process
GO:0051289	protein homotetramerization	15340920.	IPI	Process
GO:1901052	sarcosine metabolic process	21873635.	IBA	Process
GO:1904047	S-adenosyl-L-methionine binding	21873635.	IBA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
19035462	Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.	Int J Cancer	2009 Feb 15	Liao YJ	doi: 10.1002/ijc.23979.
12566309	Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer.	Cancer Res	2003 Feb 1	Tseng TL	-
21572396	The important role of glycine N-methyltransferase in the carcinogenesis and progression of prostate cancer.	Mod Pathol	2011 Sep	Song YH	doi: 10.1038/modpathol.2011.76
22850906	Genetic factors regulating inflammation and DNA methylation associated with prostate cancer.	Prostate Cancer Prostatic Dis	2013 Mar	Ianni M	doi: 10.1038/pcan.2012.30
24800880	Genetic polymorphisms of the glycine N-methyltransferase and prostate cancer risk in the health professionals follow-up study.	PLoS One	2014 May 6	Chen M	doi: 10.1371/journal.pone.0094683

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr6	42963716	3'UTR	novel		0.31
BLCA	chr6	42962290	Silent	NA	A95A	0.36
BLCA	chr6	42963142	Silent	rs752057158	V174V	0.19
BLCA	chr6	42963205	Missense_Mutation	novel	I195M	0.46
BLCA	chr6	42963161	Missense_Mutation	rs755100354	D181N	0.1
BRCA	chr6	42963643	Silent	NA	P275P	0.15
CESC	chr6	42963630	Missense_Mutation	novel	G271D	0.16
CESC	chr6	42962300	Missense_Mutation	novel	R99C	0.37	Methyltransf_31
COAD	chr6	42960915	Missense_Mutation	rs377704687	L50I	0.3
COAD	chr6	42962241	Missense_Mutation	NA	G79D	0.23	Methyltransf_31
GBM	chr6	42963342	Silent	novel	K203K	0.31
GBM	chr6	42963778	3'UTR	novel		0.72
KIRC	chr6	42962341	Splice_Site	novel	X112_splice	0.47
KIRC	chr6	42962227	Frame_Shift_Del	novel	*M74Ifs14**	0.21	Methyltransf_31
LIHC	chr6	42963422	Missense_Mutation	novel	A230D	0.15
LIHC	chr6	42963090	Missense_Mutation	rs563826316	R157Q	0.09	Methyltransf_31
LIHC	chr6	42960941	Silent	NA	C58C	0.48
LUAD	chr6	42962253	Missense_Mutation	novel	T83K	0.37	Methyltransf_31
LUAD	chr6	42963160	Silent	rs147746130	Y180Y	0.11
LUAD	chr6	42963447	Missense_Mutation	NA	L238F	0.22
LUSC	chr6	42963152	Missense_Mutation	NA	R178C	0.13	Methyltransf_31
LUSC	chr6	42963414	Silent	novel	V227V	0.46
SKCM	chr6	42963601	Silent	rs201991849	F261F	0.3
SKCM	chr6	42963543	Missense_Mutation	rs199572656	R242Q	0.13
SKCM	chr6	42963346	Missense_Mutation	rs758305053	V205I	0.41
SKCM	chr6	42963112	Silent	rs149792195	A164A	0.27
STAD	chr6	42963542	Missense_Mutation	novel	R242W	0.15
STAD	chr6	42963686	Missense_Mutation	rs370220793	V290M	0.37
STAD	chr6	42963111	Missense_Mutation	rs768654043	A164V	0.2	Methyltransf_31
STAD	chr6	42963086	Missense_Mutation	NA	H156Y	0.44	Methyltransf_31
STAD	chr6	42963379	Missense_Mutation	NA	A216T	0.38
UCEC	chr6	42963730	3'UTR	novel		0.61
UCEC	chr6	42963626	Silent	NA	L270L	0.22
UCEC	chr6	42962325	Missense_Mutation	novel	A107V	0.41	Methyltransf_31
UCEC	chr6	42963631	Silent	novel	G271G	0.59
UCEC	chr6	42962766	Silent	rs759363288	I113I	0.43
UCEC	chr6	42962819	Missense_Mutation	NA	G131D	0.29	Methyltransf_31
UCEC	chr6	42962857	Missense_Mutation	rs776654469	A144T	0.46	Methyltransf_31
UCEC	chr6	42962312	Missense_Mutation	rs749599022	R103W	0.41	Methyltransf_31
UCEC	chr6	42962857	Missense_Mutation	rs776654469	A144T	0.32	Methyltransf_31
UCEC	chr6	42963188	Frame_Shift_Del	novel	*P191Qfs11**	0.3
UCEC	chr6	42962324	Missense_Mutation	rs535188125	A107T	0.12	Methyltransf_31
UCEC	chr6	42963673	Silent	novel	C285C	0.55

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
COAD	AMP	0.1774	0.005341
READ	AMP	0.2788	0.02906

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0063	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
MESO	0.0001	Kaplan-Meier Survival Analysis
ACC	0.035	Kaplan-Meier Survival Analysis
UCS	0.0059	Kaplan-Meier Survival Analysis
HNSC	0.0034	Kaplan-Meier Survival Analysis
SKCM	0.031	Kaplan-Meier Survival Analysis
LUSC	0.019	Kaplan-Meier Survival Analysis
COAD	0.0097	Kaplan-Meier Survival Analysis
BLCA	0.012	Kaplan-Meier Survival Analysis
CESC	0.00087	Kaplan-Meier Survival Analysis
KICH	0.017	Kaplan-Meier Survival Analysis
UCEC	0.018	Kaplan-Meier Survival Analysis
GBM	0.045	Kaplan-Meier Survival Analysis
LIHC	0.0012	Kaplan-Meier Survival Analysis
LUAD	0.00011	Kaplan-Meier Survival Analysis
OV	0.045	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742