EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125107 (Gene tree)
Gene ID: 23019
Gene Symbol: CNOT1
Alias: CDC39|NOT1H|KIAA1007|AD-005|NOT1
Full Name: CCR4-NOT transcription complex subunit 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 109,941 bases
Position: chr16:58,519,946-58,629,886
Accession: 7877
RBP type: canonical RBP
Summary: (CCR4-NOT Transcription Complex Subunit 1) is a Protein Coding gene. Diseases associated with CNOT1 include Iritis. Among its related pathways are Gene Expression and TP53 Regulates Transcription of Cell Cycle Genes. Gene Ontology (GO) annotations related to this gene include protein domain specific binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000320949	Not1	PF04054.15	3.7e-152	1	1
ENSP00000455635	Not1	PF04054.15	3.8e-152	1	1
ENSP00000454611	Not1	PF04054.15	8e-16	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24697206	Phylogenetic distribution and evolution of the linked RNA-binding and NOT1-binding domains in the tristetraprolin family of tandem CCCH zinc finger proteins.	J Interferon Cytokine Res	2014 Apr	Blackshear PJ	doi: 10.1089/jir.2013.0150.
21278420	Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.	Nucleic Acids Res	2011 May	Sandler H	doi: 10.1093/nar/gkr011
24121231	Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex.	Nat Struct Mol Biol	2013 Nov	Bhaskar V	doi: 10.1038/nsmb.2686
26807845	Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7.	PLoS Genet	2016 Jan 25	Faraji F	doi: 10.1371/journal.pgen.1005820

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000569240	CNOT1-216	7660	-	ENSP00000455635	2371 (aa)	-	A5YKK6
ENST00000563283	CNOT1-205	551	-	-	- (aa)	-	-
ENST00000569020	CNOT1-215	535	-	ENSP00000457869	25 (aa)	-	H3BPF1
ENST00000563130	CNOT1-204	2280	-	-	- (aa)	-	-
ENST00000565605	CNOT1-207	739	-	ENSP00000457460	96 (aa)	-	H3BU44
ENST00000567285	CNOT1-212	722	-	ENSP00000458057	241 (aa)	-	H3BVC9
ENST00000569732	CNOT1-218	906	-	-	- (aa)	-	-
ENST00000569882	CNOT1-219	831	-	ENSP00000454377	277 (aa)	-	H3BMH0
ENST00000567188	CNOT1-211	7830	-	ENSP00000456649	2150 (aa)	-	A5YKK6
ENST00000628857	CNOT1-223	291	-	ENSP00000485782	96 (aa)	-	H3BU44
ENST00000570139	CNOT1-222	458	-	-	- (aa)	-	-
ENST00000567133	CNOT1-210	553	-	ENSP00000454763	185 (aa)	-	H3BNB1
ENST00000441024	CNOT1-202	4999	-	ENSP00000413113	1551 (aa)	-	A5YKK6
ENST00000569924	CNOT1-221	493	-	-	- (aa)	-	-
ENST00000564557	CNOT1-206	582	-	ENSP00000456975	62 (aa)	-	H3BT18
ENST00000317147	CNOT1-201	8471	-	ENSP00000320949	2376 (aa)	-	A5YKK6
ENST00000568917	CNOT1-214	1317	-	ENSP00000454611	439 (aa)	-	H3BMZ2
ENST00000562046	CNOT1-203	578	-	ENSP00000456131	193 (aa)	-	H3BR89
ENST00000566240	CNOT1-209	567	-	ENSP00000457173	68 (aa)	-	H3BTH2
ENST00000569916	CNOT1-220	599	-	-	- (aa)	-	-
ENST00000565697	CNOT1-208	385	-	ENSP00000455289	25 (aa)	-	H3BPF1
ENST00000568158	CNOT1-213	496	-	-	- (aa)	-	-
ENST00000569263	CNOT1-217	304	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000125107's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125107	Electrocardiography	2E-57	24952745
ENSG00000125107	Electrocardiography	7E-25	19305409
ENSG00000125107	Electrocardiography	1E-7	22726844
ENSG00000125107	Electrocardiography	1E-6	20062063
ENSG00000125107	Electrocardiography	3E-25	19305408

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000125107	rs7184114	16	58551465	?	Autism spectrum disorder or schizophrenia	28540026	[1.04-1.08]	1.0638298	EFO_0000692\|EFO_0003756
ENSG00000125107	rs246196	16	58540349	C	QT interval	24952745	[1.51-1.95] unit decrease	1.73	EFO_0004682
ENSG00000125107	rs37060	16	58532400	?	QT interval	22726844	[0.957-2.084] ms increase	1.52	EFO_0004682
ENSG00000125107	rs37062	16	58533334	A	Electrocardiographic traits	20062063	[3.62-8.57] % s.d. increase	6.09	EFO_0004682
ENSG00000125107	rs37062	16	58533334	G	QT interval	19305408	[1.41-2.09] msec decrease	1.75	EFO_0004682
ENSG00000125107	rs7188697	16	58588274	A	QT interval	19305409	[1.20-2.12] ms increase	1.66	EFO_0004682
ENSG00000125107	rs11867022	16	58568321	?	Red blood cell count	30595370			EFO_0004305
ENSG00000125107	rs37060	16	58532400		Pulse pressure	30224653	[0.11-0.19] unit increase	0.1471	EFO_0005763
ENSG00000125107	rs950843	16	58586981	T	QT interval	30679814	[1.56-2.39] unit increase	1.977	EFO_0004682

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125107's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125107	CNOT1	100	100.000	ENSAPOG00000005042	cnot1	100	96.914	Acanthochromis_polyacanthus
ENSG00000125107	CNOT1	100	100.000	ENSAMEG00000017298	CNOT1	100	99.747	Ailuropoda_melanoleuca
ENSG00000125107	CNOT1	100	90.433	ENSACIG00000016003	cnot1	100	90.565	Amphilophus_citrinellus
ENSG00000125107	CNOT1	100	93.394	ENSAOCG00000002859	cnot1	100	96.000	Amphiprion_ocellaris
ENSG00000125107	CNOT1	100	100.000	ENSAPEG00000022342	cnot1	100	90.660	Amphiprion_percula
ENSG00000125107	CNOT1	100	100.000	ENSATEG00000012892	cnot1	100	97.055	Anabas_testudineus
ENSG00000125107	CNOT1	100	100.000	ENSAPLG00000007162	CNOT1	100	97.647	Anas_platyrhynchos
ENSG00000125107	CNOT1	100	100.000	ENSACAG00000001602	CNOT1	98	96.197	Anolis_carolinensis
ENSG00000125107	CNOT1	100	100.000	ENSANAG00000038198	CNOT1	100	97.026	Aotus_nancymaae
ENSG00000125107	CNOT1	100	100.000	ENSACLG00000014234	cnot1	100	97.055	Astatotilapia_calliptera
ENSG00000125107	CNOT1	100	100.000	ENSAMXG00000013170	cnot1	100	91.614	Astyanax_mexicanus
ENSG00000125107	CNOT1	100	100.000	ENSBTAG00000020782	CNOT1	100	99.747	Bos_taurus
ENSG00000125107	CNOT1	96	64.615	WBGene00002845	let-711	92	54.430	Caenorhabditis_elegans
ENSG00000125107	CNOT1	100	100.000	ENSCJAG00000011318	CNOT1	100	99.874	Callithrix_jacchus
ENSG00000125107	CNOT1	100	100.000	ENSCAFG00000008426	CNOT1	100	99.412	Canis_familiaris
ENSG00000125107	CNOT1	100	100.000	ENSCAFG00020010156	CNOT1	100	99.316	Canis_lupus_dingo
ENSG00000125107	CNOT1	100	100.000	ENSCHIG00000010452	CNOT1	100	99.747	Capra_hircus
ENSG00000125107	CNOT1	100	100.000	ENSTSYG00000006888	CNOT1	100	99.874	Carlito_syrichta
ENSG00000125107	CNOT1	95	81.928	ENSCAPG00000007848	-	99	77.250	Cavia_aperea
ENSG00000125107	CNOT1	100	100.000	ENSCPOG00000013026	CNOT1	100	95.034	Cavia_porcellus
ENSG00000125107	CNOT1	100	100.000	ENSCCAG00000026333	CNOT1	100	98.316	Cebus_capucinus
ENSG00000125107	CNOT1	100	100.000	ENSCATG00000032625	CNOT1	100	99.958	Cercocebus_atys
ENSG00000125107	CNOT1	100	100.000	ENSCLAG00000006289	CNOT1	100	99.663	Chinchilla_lanigera
ENSG00000125107	CNOT1	100	100.000	ENSCSAG00000004731	CNOT1	100	99.958	Chlorocebus_sabaeus
ENSG00000125107	CNOT1	100	100.000	ENSCHOG00000009712	CNOT1	83	100.000	Choloepus_hoffmanni
ENSG00000125107	CNOT1	99	98.858	ENSCPBG00000026222	CNOT1	99	98.611	Chrysemys_picta_bellii
ENSG00000125107	CNOT1	100	92.000	ENSCING00000009149	-	100	58.658	Ciona_intestinalis
ENSG00000125107	CNOT1	96	87.500	ENSCSAVG00000002414	-	95	78.808	Ciona_savignyi
ENSG00000125107	CNOT1	100	100.000	ENSCANG00000040534	CNOT1	100	97.827	Colobus_angolensis_palliatus
ENSG00000125107	CNOT1	100	100.000	ENSCGRG00001016365	Cnot1	100	99.327	Cricetulus_griseus_chok1gshd
ENSG00000125107	CNOT1	100	100.000	ENSCGRG00000001714	Cnot1	100	99.327	Cricetulus_griseus_crigri
ENSG00000125107	CNOT1	100	89.616	ENSCSEG00000021493	cnot1	100	93.727	Cynoglossus_semilaevis
ENSG00000125107	CNOT1	100	100.000	ENSCVAG00000018930	cnot1	100	83.159	Cyprinodon_variegatus
ENSG00000125107	CNOT1	100	100.000	ENSDARG00000004174	cnot1	100	90.046	Danio_rerio
ENSG00000125107	CNOT1	100	100.000	ENSDNOG00000013250	CNOT1	100	97.181	Dasypus_novemcinctus
ENSG00000125107	CNOT1	100	98.405	ENSDORG00000002101	-	100	100.000	Dipodomys_ordii
ENSG00000125107	CNOT1	94	57.812	FBgn0085436	Not1	99	48.431	Drosophila_melanogaster
ENSG00000125107	CNOT1	100	100.000	ENSETEG00000012806	CNOT1	84	97.590	Echinops_telfairi
ENSG00000125107	CNOT1	100	96.000	ENSEBUG00000011534	cnot1	86	86.937	Eptatretus_burgeri
ENSG00000125107	CNOT1	100	100.000	ENSEASG00005005819	CNOT1	100	98.802	Equus_asinus_asinus
ENSG00000125107	CNOT1	100	100.000	ENSECAG00000009889	CNOT1	100	99.813	Equus_caballus
ENSG00000125107	CNOT1	100	100.000	ENSEEUG00000006015	CNOT1	90	99.373	Erinaceus_europaeus
ENSG00000125107	CNOT1	100	100.000	ENSELUG00000014085	cnot1	100	89.685	Esox_lucius
ENSG00000125107	CNOT1	100	100.000	ENSFCAG00000025155	CNOT1	100	99.496	Felis_catus
ENSG00000125107	CNOT1	100	100.000	ENSFALG00000007285	CNOT1	100	97.685	Ficedula_albicollis
ENSG00000125107	CNOT1	100	100.000	ENSFDAG00000013399	CNOT1	100	99.579	Fukomys_damarensis
ENSG00000125107	CNOT1	100	100.000	ENSFHEG00000020574	cnot1	100	90.340	Fundulus_heteroclitus
ENSG00000125107	CNOT1	100	100.000	ENSGMOG00000012864	cnot1	100	90.028	Gadus_morhua
ENSG00000125107	CNOT1	100	100.000	ENSGALG00000002301	CNOT1	100	97.727	Gallus_gallus
ENSG00000125107	CNOT1	100	100.000	ENSGAFG00000015005	cnot1	100	89.356	Gambusia_affinis
ENSG00000125107	CNOT1	100	100.000	ENSGACG00000002606	cnot1	100	95.752	Gasterosteus_aculeatus
ENSG00000125107	CNOT1	100	100.000	ENSGAGG00000022646	CNOT1	100	97.897	Gopherus_agassizii
ENSG00000125107	CNOT1	100	100.000	ENSGGOG00000009547	CNOT1	100	99.958	Gorilla_gorilla
ENSG00000125107	CNOT1	100	100.000	ENSHBUG00000001729	cnot1	100	97.055	Haplochromis_burtoni
ENSG00000125107	CNOT1	100	100.000	ENSHGLG00000014322	CNOT1	100	99.495	Heterocephalus_glaber_female
ENSG00000125107	CNOT1	100	100.000	ENSHCOG00000006501	cnot1	100	89.749	Hippocampus_comes
ENSG00000125107	CNOT1	100	100.000	ENSIPUG00000011915	cnot1	100	89.491	Ictalurus_punctatus
ENSG00000125107	CNOT1	100	100.000	ENSSTOG00000005490	CNOT1	100	99.579	Ictidomys_tridecemlineatus
ENSG00000125107	CNOT1	100	100.000	ENSJJAG00000000633	Cnot1	100	98.990	Jaculus_jaculus
ENSG00000125107	CNOT1	100	100.000	ENSKMAG00000006149	cnot1	100	90.323	Kryptolebias_marmoratus
ENSG00000125107	CNOT1	100	100.000	ENSLBEG00000004740	cnot1	100	96.407	Labrus_bergylta
ENSG00000125107	CNOT1	100	100.000	ENSLACG00000010869	CNOT1	100	95.076	Latimeria_chalumnae
ENSG00000125107	CNOT1	100	100.000	ENSLOCG00000006324	cnot1	100	93.274	Lepisosteus_oculatus
ENSG00000125107	CNOT1	100	100.000	ENSLAFG00000000098	CNOT1	100	99.537	Loxodonta_africana
ENSG00000125107	CNOT1	100	100.000	ENSMFAG00000035888	CNOT1	100	99.958	Macaca_fascicularis
ENSG00000125107	CNOT1	100	100.000	ENSMMUG00000014625	CNOT1	100	99.916	Macaca_mulatta
ENSG00000125107	CNOT1	100	100.000	ENSMNEG00000031820	CNOT1	100	99.953	Macaca_nemestrina
ENSG00000125107	CNOT1	100	100.000	ENSMLEG00000040933	CNOT1	100	98.527	Mandrillus_leucophaeus
ENSG00000125107	CNOT1	100	100.000	ENSMAMG00000016524	cnot1	100	89.398	Mastacembelus_armatus
ENSG00000125107	CNOT1	100	100.000	ENSMZEG00005016210	cnot1	100	97.055	Maylandia_zebra
ENSG00000125107	CNOT1	100	100.000	ENSMGAG00000001908	CNOT1	100	97.722	Meleagris_gallopavo
ENSG00000125107	CNOT1	100	98.178	ENSMAUG00000009731	-	99	99.877	Mesocricetus_auratus
ENSG00000125107	CNOT1	100	100.000	ENSMICG00000007071	CNOT1	100	99.579	Microcebus_murinus
ENSG00000125107	CNOT1	100	100.000	ENSMOCG00000017969	Cnot1	100	99.369	Microtus_ochrogaster
ENSG00000125107	CNOT1	100	100.000	ENSMMOG00000019134	cnot1	100	93.689	Mola_mola
ENSG00000125107	CNOT1	100	100.000	ENSMODG00000014199	CNOT1	100	97.897	Monodelphis_domestica
ENSG00000125107	CNOT1	100	100.000	ENSMALG00000008645	cnot1	100	90.446	Monopterus_albus
ENSG00000125107	CNOT1	100	100.000	MGP_CAROLIEiJ_G0031430	Cnot1	92	99.889	Mus_caroli
ENSG00000125107	CNOT1	100	100.000	ENSMUSG00000036550	Cnot1	100	99.411	Mus_musculus
ENSG00000125107	CNOT1	100	100.000	MGP_PahariEiJ_G0023028	Cnot1	100	99.369	Mus_pahari
ENSG00000125107	CNOT1	100	100.000	MGP_SPRETEiJ_G0032549	Cnot1	100	99.411	Mus_spretus
ENSG00000125107	CNOT1	100	100.000	ENSMPUG00000004830	CNOT1	100	99.790	Mustela_putorius_furo
ENSG00000125107	CNOT1	100	100.000	ENSMLUG00000003728	CNOT1	100	99.116	Myotis_lucifugus
ENSG00000125107	CNOT1	100	100.000	ENSNGAG00000018628	Cnot1	100	99.621	Nannospalax_galili
ENSG00000125107	CNOT1	100	100.000	ENSNBRG00000019358	cnot1	100	97.055	Neolamprologus_brichardi
ENSG00000125107	CNOT1	100	100.000	ENSNLEG00000003566	CNOT1	100	99.916	Nomascus_leucogenys
ENSG00000125107	CNOT1	100	100.000	ENSMEUG00000006145	CNOT1	87	98.434	Notamacropus_eugenii
ENSG00000125107	CNOT1	100	100.000	ENSOPRG00000005604	CNOT1	86	100.000	Ochotona_princeps
ENSG00000125107	CNOT1	100	100.000	ENSODEG00000016337	CNOT1	100	99.537	Octodon_degus
ENSG00000125107	CNOT1	100	100.000	ENSONIG00000007358	cnot1	100	90.444	Oreochromis_niloticus
ENSG00000125107	CNOT1	100	100.000	ENSOANG00000012109	CNOT1	100	98.354	Ornithorhynchus_anatinus
ENSG00000125107	CNOT1	100	100.000	ENSOCUG00000006911	CNOT1	100	99.705	Oryctolagus_cuniculus
ENSG00000125107	CNOT1	100	100.000	ENSORLG00000013734	cnot1	100	90.626	Oryzias_latipes
ENSG00000125107	CNOT1	100	100.000	ENSORLG00020017012	cnot1	100	88.777	Oryzias_latipes_hni
ENSG00000125107	CNOT1	100	100.000	ENSORLG00015007091	cnot1	100	88.525	Oryzias_latipes_hsok
ENSG00000125107	CNOT1	100	100.000	ENSOMEG00000015124	cnot1	100	88.641	Oryzias_melastigma
ENSG00000125107	CNOT1	100	100.000	ENSOGAG00000000543	CNOT1	100	99.621	Otolemur_garnettii
ENSG00000125107	CNOT1	100	100.000	ENSOARG00000001567	CNOT1	100	99.747	Ovis_aries
ENSG00000125107	CNOT1	100	100.000	ENSPPAG00000022013	CNOT1	100	100.000	Pan_paniscus
ENSG00000125107	CNOT1	100	100.000	ENSPPRG00000004867	CNOT1	100	99.790	Panthera_pardus
ENSG00000125107	CNOT1	100	100.000	ENSPTIG00000012589	CNOT1	100	99.790	Panthera_tigris_altaica
ENSG00000125107	CNOT1	100	100.000	ENSPTRG00000008183	CNOT1	100	99.706	Pan_troglodytes
ENSG00000125107	CNOT1	100	100.000	ENSPANG00000020901	CNOT1	100	96.396	Papio_anubis
ENSG00000125107	CNOT1	100	100.000	ENSPKIG00000023538	CNOT1	100	92.515	Paramormyrops_kingsleyae
ENSG00000125107	CNOT1	100	100.000	ENSPKIG00000002914	CNOT1	99	93.258	Paramormyrops_kingsleyae
ENSG00000125107	CNOT1	100	100.000	ENSPSIG00000005499	CNOT1	100	97.769	Pelodiscus_sinensis
ENSG00000125107	CNOT1	54	94.492	ENSPMGG00000002161	-	100	97.802	Periophthalmus_magnuspinnatus
ENSG00000125107	CNOT1	100	97.267	ENSPEMG00000014520	-	100	95.146	Peromyscus_maniculatus_bairdii
ENSG00000125107	CNOT1	100	96.000	ENSPMAG00000009381	cnot1	100	81.279	Petromyzon_marinus
ENSG00000125107	CNOT1	100	100.000	ENSPCIG00000007343	CNOT1	100	98.611	Phascolarctos_cinereus
ENSG00000125107	CNOT1	100	100.000	ENSPFOG00000003497	cnot1	100	90.085	Poecilia_formosa
ENSG00000125107	CNOT1	100	100.000	ENSPLAG00000014018	cnot1	100	96.008	Poecilia_latipinna
ENSG00000125107	CNOT1	100	100.000	ENSPMEG00000005868	cnot1	100	96.008	Poecilia_mexicana
ENSG00000125107	CNOT1	100	100.000	ENSPREG00000018793	cnot1	100	96.008	Poecilia_reticulata
ENSG00000125107	CNOT1	100	100.000	ENSPPYG00000007410	CNOT1	100	99.958	Pongo_abelii
ENSG00000125107	CNOT1	100	98.201	ENSPCAG00000003241	CNOT1	90	97.530	Procavia_capensis
ENSG00000125107	CNOT1	100	100.000	ENSPCOG00000027139	CNOT1	100	99.329	Propithecus_coquereli
ENSG00000125107	CNOT1	100	100.000	ENSPVAG00000004243	CNOT1	100	97.180	Pteropus_vampyrus
ENSG00000125107	CNOT1	100	100.000	ENSPNYG00000012919	cnot1	100	97.055	Pundamilia_nyererei
ENSG00000125107	CNOT1	100	100.000	ENSPNAG00000000246	cnot1	100	90.514	Pygocentrus_nattereri
ENSG00000125107	CNOT1	100	100.000	ENSRNOG00000012271	Cnot1	100	99.327	Rattus_norvegicus
ENSG00000125107	CNOT1	100	100.000	ENSRBIG00000044598	CNOT1	100	97.608	Rhinopithecus_bieti
ENSG00000125107	CNOT1	100	100.000	ENSRROG00000000906	CNOT1	100	99.958	Rhinopithecus_roxellana
ENSG00000125107	CNOT1	84	36.842	YCR093W	CDC39	68	34.074	Saccharomyces_cerevisiae
ENSG00000125107	CNOT1	100	100.000	ENSSBOG00000029155	CNOT1	100	95.479	Saimiri_boliviensis_boliviensis
ENSG00000125107	CNOT1	100	100.000	ENSSHAG00000012187	CNOT1	100	98.150	Sarcophilus_harrisii
ENSG00000125107	CNOT1	100	100.000	ENSSFOG00015017614	cnot1	100	90.584	Scleropages_formosus
ENSG00000125107	CNOT1	100	100.000	ENSSMAG00000013844	cnot1	100	97.055	Scophthalmus_maximus
ENSG00000125107	CNOT1	100	100.000	ENSSDUG00000021491	cnot1	100	96.914	Seriola_dumerili
ENSG00000125107	CNOT1	100	100.000	ENSSLDG00000014816	cnot1	100	96.914	Seriola_lalandi_dorsalis
ENSG00000125107	CNOT1	100	99.281	ENSSARG00000000762	CNOT1	88	100.000	Sorex_araneus
ENSG00000125107	CNOT1	100	100.000	ENSSPAG00000018802	cnot1	100	90.580	Stegastes_partitus
ENSG00000125107	CNOT1	100	100.000	ENSSSCG00000002799	CNOT1	100	99.621	Sus_scrofa
ENSG00000125107	CNOT1	100	100.000	ENSTGUG00000005919	CNOT1	100	97.562	Taeniopygia_guttata
ENSG00000125107	CNOT1	100	93.850	ENSTRUG00000001784	cnot1	100	96.117	Takifugu_rubripes
ENSG00000125107	CNOT1	100	100.000	ENSTNIG00000018706	cnot1	100	89.144	Tetraodon_nigroviridis
ENSG00000125107	CNOT1	100	100.000	ENSTBEG00000000720	CNOT1	80	100.000	Tupaia_belangeri
ENSG00000125107	CNOT1	100	100.000	ENSTTRG00000008460	CNOT1	95	99.534	Tursiops_truncatus
ENSG00000125107	CNOT1	100	100.000	ENSUAMG00000009251	CNOT1	100	99.790	Ursus_americanus
ENSG00000125107	CNOT1	100	100.000	ENSUMAG00000021291	CNOT1	100	99.790	Ursus_maritimus
ENSG00000125107	CNOT1	100	100.000	ENSVPAG00000008846	CNOT1	97	97.244	Vicugna_pacos
ENSG00000125107	CNOT1	100	100.000	ENSVVUG00000024037	CNOT1	100	99.316	Vulpes_vulpes
ENSG00000125107	CNOT1	100	100.000	ENSXETG00000015900	cnot1	100	90.282	Xenopus_tropicalis
ENSG00000125107	CNOT1	100	100.000	ENSXCOG00000013552	cnot1	100	89.525	Xiphophorus_couchianus
ENSG00000125107	CNOT1	100	100.000	ENSXMAG00000006031	cnot1	100	89.567	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	16778766.	IDA	Process
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	-	TAS	Process
GO:0000932	P-body	21873635.	IBA	Component
GO:0000932	P-body	21976065.	IDA	Component
GO:0000932	P-body	-	ISS	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004535	poly(A)-specific ribonuclease activity	21976065.	IDA	Function
GO:0005515	protein binding	10637334.16778766.17452450.18377426.21278420.21981923.21984185.22977175.23232451.23463101.23644599.24736845.24768540.25038453.26496610.	IPI	Function
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	-	TAS	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	21976065.	IDA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0017148	negative regulation of translation	21873635.	IBA	Process
GO:0017148	negative regulation of translation	24736845.	IDA	Process
GO:0019904	protein domain specific binding	24768540.	IPI	Function
GO:0030014	CCR4-NOT complex	19558367.	IDA	Component
GO:0030015	CCR4-NOT core complex	-	IEA	Component
GO:0030331	estrogen receptor binding	16778766.	IDA	Function
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	16778766.	IDA	Process
GO:0035195	gene silencing by miRNA	23172285.24768540.	IDA	Process
GO:0042974	retinoic acid receptor binding	16778766.	IDA	Function
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	16778766.	IDA	Process
GO:0060090	molecular adaptor activity	21873635.	IBA	Function
GO:0060090	molecular adaptor activity	22977175.	IDA	Function
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	23644599.	IDA	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	21278420.	IMP	Process
GO:0061014	positive regulation of mRNA catabolic process	22977175.	IMP	Process
GO:0070016	armadillo repeat domain binding	24768540.	IPI	Function
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	21278420.	IMP	Process
GO:2000036	regulation of stem cell population maintenance	21873635.	IBA	Process
GO:2000036	regulation of stem cell population maintenance	22367759.	IMP	Process