EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125351 (Gene tree)
Gene ID: 65109
Gene Symbol: UPF3B
Alias: RENT3B|UPF3X|HUPF3B|MRX62|UPF3BP1|UPF3BP2|UPF3BP3
Full Name: UPF3B regulator of nonsense mediated mRNA decay
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 47,718 bases
Position: chrX:119,805,311-119,853,028
Accession: 20439
RBP type: canonical RBP
Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000481698	Smg4_UPF3	PF03467.15	3.1e-54	1	1
ENSP00000245418	Smg4_UPF3	PF03467.15	2.1e-53	1	1
ENSP00000276201	Smg4_UPF3	PF03467.15	2.3e-53	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27475226	Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.	Cell Rep	2016 Aug 9	Hauer C	doi: 10.1016/j.celrep.2016.06.096
15004547	The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3.	Nat Struct Mol Biol	2004 Apr	Kadlec J	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000636792	UPF3B-205	834	-	ENSP00000490431	232 (aa)	-	A0A1B0GVA2
ENST00000478840	UPF3B-203	748	-	-	- (aa)	-	-
ENST00000345865	UPF3B-202	2335	XM_017029739	ENSP00000245418	470 (aa)	XP_016885228	Q9BZI7
ENST00000619445	UPF3B-204	1385	-	ENSP00000481698	217 (aa)	-	A0A087WYC8
ENST00000276201	UPF3B-201	2378	XM_017029737	ENSP00000276201	483 (aa)	XP_016885226	Q9BZI7

Gene Model

Click here to download ENSG00000125351's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa03015	mRNA surveillance pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125351's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000125351	UPF3B	76	70.122	ENSG00000169062	UPF3A	51	64.032

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125351	UPF3B	96	69.048	ENSAPOG00000012775	upf3b	68	63.030	Acanthochromis_polyacanthus
ENSG00000125351	UPF3B	100	95.859	ENSAMEG00000000163	UPF3B	100	95.859	Ailuropoda_melanoleuca
ENSG00000125351	UPF3B	91	58.794	ENSAMEG00000004259	UPF3A	57	51.685	Ailuropoda_melanoleuca
ENSG00000125351	UPF3B	76	70.732	ENSACIG00000020468	upf3a	83	66.129	Amphilophus_citrinellus
ENSG00000125351	UPF3B	96	64.286	ENSACIG00000013582	upf3b	94	51.762	Amphilophus_citrinellus
ENSG00000125351	UPF3B	96	67.143	ENSAOCG00000000706	upf3b	64	63.754	Amphiprion_ocellaris
ENSG00000125351	UPF3B	96	69.048	ENSAPEG00000005545	upf3b	99	53.125	Amphiprion_percula
ENSG00000125351	UPF3B	96	69.524	ENSATEG00000018742	upf3b	95	55.460	Anabas_testudineus
ENSG00000125351	UPF3B	77	85.030	ENSACAG00000003625	UPF3B	99	67.227	Anolis_carolinensis
ENSG00000125351	UPF3B	72	69.872	ENSACAG00000001540	UPF3A	94	51.214	Anolis_carolinensis
ENSG00000125351	UPF3B	89	82.902	ENSANAG00000033169	-	95	70.438	Aotus_nancymaae
ENSG00000125351	UPF3B	100	97.930	ENSANAG00000021894	-	100	98.885	Aotus_nancymaae
ENSG00000125351	UPF3B	100	92.128	ENSANAG00000025598	-	100	92.593	Aotus_nancymaae
ENSG00000125351	UPF3B	96	66.507	ENSACLG00000001649	upf3b	63	65.798	Astatotilapia_calliptera
ENSG00000125351	UPF3B	91	62.814	ENSAMXG00000000199	upf3b	88	58.719	Astyanax_mexicanus
ENSG00000125351	UPF3B	74	67.702	ENSBTAG00000047365	-	72	68.125	Bos_taurus
ENSG00000125351	UPF3B	96	98.077	ENSBTAG00000035615	UPF3B	100	98.141	Bos_taurus
ENSG00000125351	UPF3B	79	31.638	WBGene00004882	smg-4	53	30.508	Caenorhabditis_elegans
ENSG00000125351	UPF3B	100	97.930	ENSCJAG00000004975	UPF3B	100	98.885	Callithrix_jacchus
ENSG00000125351	UPF3B	88	63.684	ENSCAFG00000006504	UPF3A	59	52.857	Canis_familiaris
ENSG00000125351	UPF3B	100	95.031	ENSCAFG00000018426	UPF3B	100	94.410	Canis_familiaris
ENSG00000125351	UPF3B	86	64.171	ENSCAFG00020014268	UPF3A	58	52.857	Canis_lupus_dingo
ENSG00000125351	UPF3B	100	92.553	ENSCAFG00020004074	UPF3B	100	91.915	Canis_lupus_dingo
ENSG00000125351	UPF3B	96	97.596	ENSCHIG00000018011	-	100	97.770	Capra_hircus
ENSG00000125351	UPF3B	90	64.706	ENSCHIG00000011454	-	92	62.824	Capra_hircus
ENSG00000125351	UPF3B	100	95.859	ENSCHIG00000000247	-	100	95.859	Capra_hircus
ENSG00000125351	UPF3B	100	95.319	ENSTSYG00000014690	UPF3B	100	94.700	Carlito_syrichta
ENSG00000125351	UPF3B	96	55.814	ENSCCAG00000021964	-	100	76.056	Cebus_capucinus
ENSG00000125351	UPF3B	93	82.587	ENSCCAG00000029813	-	99	59.574	Cebus_capucinus
ENSG00000125351	UPF3B	100	99.793	ENSCATG00000017506	UPF3B	100	100.000	Cercocebus_atys
ENSG00000125351	UPF3B	76	70.732	ENSCATG00000029733	UPF3A	53	64.427	Cercocebus_atys
ENSG00000125351	UPF3B	100	91.915	ENSCLAG00000003260	UPF3B	100	91.915	Chinchilla_lanigera
ENSG00000125351	UPF3B	100	100.000	ENSCSAG00000018348	UPF3B	100	100.000	Chlorocebus_sabaeus
ENSG00000125351	UPF3B	76	69.461	ENSCSAG00000017388	UPF3A	53	63.672	Chlorocebus_sabaeus
ENSG00000125351	UPF3B	99	66.109	ENSCPBG00000020685	UPF3B	93	68.578	Chrysemys_picta_bellii
ENSG00000125351	UPF3B	76	47.879	ENSCING00000008396	-	91	51.370	Ciona_intestinalis
ENSG00000125351	UPF3B	99	98.131	ENSCANG00000029220	UPF3B	100	100.000	Colobus_angolensis_palliatus
ENSG00000125351	UPF3B	96	87.019	ENSCGRG00001013643	-	89	81.098	Cricetulus_griseus_chok1gshd
ENSG00000125351	UPF3B	96	87.500	ENSCGRG00001006858	-	100	83.263	Cricetulus_griseus_chok1gshd
ENSG00000125351	UPF3B	89	85.000	ENSCGRG00000007627	Upf3b	100	85.238	Cricetulus_griseus_crigri
ENSG00000125351	UPF3B	96	66.981	ENSCSEG00000002046	upf3b	66	60.241	Cynoglossus_semilaevis
ENSG00000125351	UPF3B	96	66.029	ENSCVAG00000005030	upf3b	99	51.163	Cyprinodon_variegatus
ENSG00000125351	UPF3B	96	65.714	ENSDARG00000000489	upf3b	97	57.082	Danio_rerio
ENSG00000125351	UPF3B	76	67.073	ENSDNOG00000034391	UPF3A	58	60.448	Dasypus_novemcinctus
ENSG00000125351	UPF3B	100	94.617	ENSDNOG00000008665	UPF3B	100	94.617	Dasypus_novemcinctus
ENSG00000125351	UPF3B	100	87.872	ENSDORG00000006077	Upf3b	100	87.234	Dipodomys_ordii
ENSG00000125351	UPF3B	88	63.158	ENSEASG00005021884	UPF3A	52	55.422	Equus_asinus_asinus
ENSG00000125351	UPF3B	99	95.434	ENSEASG00005012919	UPF3B	100	92.964	Equus_asinus_asinus
ENSG00000125351	UPF3B	99	95.434	ENSECAG00000016947	UPF3B	100	92.964	Equus_caballus
ENSG00000125351	UPF3B	88	63.158	ENSECAG00000017141	UPF3A	52	55.422	Equus_caballus
ENSG00000125351	UPF3B	96	67.619	ENSELUG00000020389	upf3b	65	61.194	Esox_lucius
ENSG00000125351	UPF3B	100	94.227	ENSFCAG00000004388	UPF3B	100	94.433	Felis_catus
ENSG00000125351	UPF3B	76	68.902	ENSFCAG00000014602	UPF3A	55	54.887	Felis_catus
ENSG00000125351	UPF3B	96	73.611	ENSFALG00000001569	UPF3B	99	63.618	Ficedula_albicollis
ENSG00000125351	UPF3B	100	93.191	ENSFDAG00000018869	UPF3B	100	93.191	Fukomys_damarensis
ENSG00000125351	UPF3B	61	60.135	ENSFHEG00000010418	upf3a	79	61.379	Fundulus_heteroclitus
ENSG00000125351	UPF3B	96	66.029	ENSFHEG00000017895	upf3b	63	63.036	Fundulus_heteroclitus
ENSG00000125351	UPF3B	96	65.403	ENSGMOG00000001621	upf3b	61	63.763	Gadus_morhua
ENSG00000125351	UPF3B	69	75.333	ENSGALG00000016815	-	70	75.333	Gallus_gallus
ENSG00000125351	UPF3B	95	72.038	ENSGALG00000008618	UPF3B	99	69.102	Gallus_gallus
ENSG00000125351	UPF3B	96	65.550	ENSGAFG00000000829	upf3b	96	55.098	Gambusia_affinis
ENSG00000125351	UPF3B	96	65.550	ENSGACG00000017435	upf3b	94	66.912	Gasterosteus_aculeatus
ENSG00000125351	UPF3B	65	73.944	ENSGAGG00000001952	UPF3A	81	73.944	Gopherus_agassizii
ENSG00000125351	UPF3B	95	74.641	ENSGAGG00000001219	UPF3B	99	65.854	Gopherus_agassizii
ENSG00000125351	UPF3B	100	100.000	ENSGGOG00000023995	UPF3B	100	100.000	Gorilla_gorilla
ENSG00000125351	UPF3B	96	66.507	ENSHBUG00000017393	upf3b	63	65.798	Haplochromis_burtoni
ENSG00000125351	UPF3B	95	85.507	ENSHGLG00000011189	-	95	86.000	Heterocephalus_glaber_female
ENSG00000125351	UPF3B	100	93.404	ENSHGLG00000019582	-	100	93.404	Heterocephalus_glaber_female
ENSG00000125351	UPF3B	96	95.192	ENSHGLG00100002042	-	100	90.000	Heterocephalus_glaber_male
ENSG00000125351	UPF3B	95	85.507	ENSHGLG00100001889	-	95	85.500	Heterocephalus_glaber_male
ENSG00000125351	UPF3B	82	67.978	ENSHCOG00000013985	upf3a	69	70.482	Hippocampus_comes
ENSG00000125351	UPF3B	96	68.095	ENSHCOG00000017004	upf3b	93	54.889	Hippocampus_comes
ENSG00000125351	UPF3B	96	65.072	ENSIPUG00000019249	upf3b	98	57.447	Ictalurus_punctatus
ENSG00000125351	UPF3B	77	63.095	ENSSTOG00000030282	-	68	63.975	Ictidomys_tridecemlineatus
ENSG00000125351	UPF3B	100	92.766	ENSSTOG00000001101	UPF3B	100	92.766	Ictidomys_tridecemlineatus
ENSG00000125351	UPF3B	70	66.887	ENSJJAG00000018099	-	70	67.333	Jaculus_jaculus
ENSG00000125351	UPF3B	96	93.750	ENSJJAG00000000053	Upf3b	100	88.771	Jaculus_jaculus
ENSG00000125351	UPF3B	96	67.143	ENSKMAG00000020300	upf3b	64	64.821	Kryptolebias_marmoratus
ENSG00000125351	UPF3B	96	67.143	ENSLBEG00000028689	upf3b	59	65.505	Labrus_bergylta
ENSG00000125351	UPF3B	66	37.647	ENSLACG00000006645	UPF3A	75	67.308	Latimeria_chalumnae
ENSG00000125351	UPF3B	95	69.082	ENSLACG00000008691	UPF3B	100	59.548	Latimeria_chalumnae
ENSG00000125351	UPF3B	76	73.780	ENSLOCG00000002665	upf3a	59	62.724	Lepisosteus_oculatus
ENSG00000125351	UPF3B	96	66.667	ENSLOCG00000015238	upf3b	92	61.893	Lepisosteus_oculatus
ENSG00000125351	UPF3B	72	67.516	ENSLAFG00000023358	UPF3A	99	43.468	Loxodonta_africana
ENSG00000125351	UPF3B	96	97.129	ENSLAFG00000001267	UPF3B	100	92.979	Loxodonta_africana
ENSG00000125351	UPF3B	100	69.869	ENSMFAG00000045275	-	100	69.869	Macaca_fascicularis
ENSG00000125351	UPF3B	100	99.586	ENSMFAG00000045414	UPF3B	100	100.000	Macaca_fascicularis
ENSG00000125351	UPF3B	100	99.586	ENSMMUG00000020222	UPF3B	100	100.000	Macaca_mulatta
ENSG00000125351	UPF3B	100	67.686	ENSMMUG00000046682	-	100	64.629	Macaca_mulatta
ENSG00000125351	UPF3B	72	70.513	ENSMMUG00000007449	UPF3A	53	64.082	Macaca_mulatta
ENSG00000125351	UPF3B	100	99.586	ENSMNEG00000039794	UPF3B	100	100.000	Macaca_nemestrina
ENSG00000125351	UPF3B	72	70.064	ENSMNEG00000036402	UPF3A	50	63.821	Macaca_nemestrina
ENSG00000125351	UPF3B	100	69.432	ENSMNEG00000040898	-	100	69.432	Macaca_nemestrina
ENSG00000125351	UPF3B	72	70.064	ENSMLEG00000014726	UPF3A	57	63.821	Mandrillus_leucophaeus
ENSG00000125351	UPF3B	100	99.793	ENSMLEG00000010999	UPF3B	100	100.000	Mandrillus_leucophaeus
ENSG00000125351	UPF3B	96	66.507	ENSMZEG00005007871	upf3b	63	65.798	Maylandia_zebra
ENSG00000125351	UPF3B	81	67.766	ENSMGAG00000007728	UPF3B	99	70.361	Meleagris_gallopavo
ENSG00000125351	UPF3B	85	50.478	ENSMGAG00000014837	UPF3A	98	49.880	Meleagris_gallopavo
ENSG00000125351	UPF3B	96	88.462	ENSMAUG00000008705	Upf3b	100	84.330	Mesocricetus_auratus
ENSG00000125351	UPF3B	99	96.729	ENSMICG00000001743	UPF3B	100	97.407	Microcebus_murinus
ENSG00000125351	UPF3B	96	93.269	ENSMOCG00000017893	Upf3b	100	85.507	Microtus_ochrogaster
ENSG00000125351	UPF3B	96	63.981	ENSMMOG00000004183	upf3b	96	54.762	Mola_mola
ENSG00000125351	UPF3B	89	75.117	ENSMODG00000010232	UPF3B	99	74.588	Monodelphis_domestica
ENSG00000125351	UPF3B	73	70.440	ENSMODG00000003159	UPF3A	96	52.448	Monodelphis_domestica
ENSG00000125351	UPF3B	53	70.435	ENSMALG00000002454	-	59	73.585	Monopterus_albus
ENSG00000125351	UPF3B	96	67.943	ENSMALG00000008042	upf3b	66	63.889	Monopterus_albus
ENSG00000125351	UPF3B	96	89.423	MGP_CAROLIEiJ_G0032999	Upf3b	100	84.958	Mus_caroli
ENSG00000125351	UPF3B	96	89.904	ENSMUSG00000036572	Upf3b	100	84.746	Mus_musculus
ENSG00000125351	UPF3B	96	88.942	MGP_PahariEiJ_G0031543	Upf3b	100	84.110	Mus_pahari
ENSG00000125351	UPF3B	96	89.904	MGP_SPRETEiJ_G0034152	Upf3b	100	84.746	Mus_spretus
ENSG00000125351	UPF3B	96	97.596	ENSMPUG00000001531	UPF3B	100	94.118	Mustela_putorius_furo
ENSG00000125351	UPF3B	91	60.914	ENSMPUG00000009139	UPF3A	51	54.839	Mustela_putorius_furo
ENSG00000125351	UPF3B	72	68.944	ENSMLUG00000015905	UPF3A	55	56.118	Myotis_lucifugus
ENSG00000125351	UPF3B	100	94.468	ENSMLUG00000010821	UPF3B	100	94.468	Myotis_lucifugus
ENSG00000125351	UPF3B	96	90.385	ENSNGAG00000008231	Upf3b	100	84.746	Nannospalax_galili
ENSG00000125351	UPF3B	97	61.611	ENSNBRG00000011560	upf3b	95	64.516	Neolamprologus_brichardi
ENSG00000125351	UPF3B	76	69.512	ENSNLEG00000007563	UPF3A	51	63.636	Nomascus_leucogenys
ENSG00000125351	UPF3B	100	99.586	ENSNLEG00000014897	UPF3B	100	99.586	Nomascus_leucogenys
ENSG00000125351	UPF3B	100	75.342	ENSNLEG00000027516	-	100	75.342	Nomascus_leucogenys
ENSG00000125351	UPF3B	71	83.871	ENSMEUG00000015615	UPF3B	81	83.974	Notamacropus_eugenii
ENSG00000125351	UPF3B	75	64.815	ENSODEG00000009176	-	66	63.636	Octodon_degus
ENSG00000125351	UPF3B	96	96.635	ENSODEG00000002186	-	100	87.447	Octodon_degus
ENSG00000125351	UPF3B	99	77.982	ENSODEG00000007164	-	93	77.523	Octodon_degus
ENSG00000125351	UPF3B	100	68.493	ENSODEG00000000596	-	100	68.493	Octodon_degus
ENSG00000125351	UPF3B	99	71.963	ENSODEG00000006064	-	98	71.296	Octodon_degus
ENSG00000125351	UPF3B	96	68.900	ENSONIG00000002536	upf3b	100	54.451	Oreochromis_niloticus
ENSG00000125351	UPF3B	72	55.769	ENSOANG00000006985	-	68	52.688	Ornithorhynchus_anatinus
ENSG00000125351	UPF3B	73	84.810	ENSOANG00000002594	-	99	64.237	Ornithorhynchus_anatinus
ENSG00000125351	UPF3B	100	95.031	ENSOCUG00000010213	UPF3B	100	95.031	Oryctolagus_cuniculus
ENSG00000125351	UPF3B	96	64.929	ENSORLG00000001026	upf3b	94	56.264	Oryzias_latipes
ENSG00000125351	UPF3B	76	71.951	ENSORLG00020014317	upf3a	82	50.976	Oryzias_latipes_hni
ENSG00000125351	UPF3B	96	64.455	ENSORLG00020003758	upf3b	94	55.580	Oryzias_latipes_hni
ENSG00000125351	UPF3B	96	64.455	ENSORLG00015012954	upf3b	94	55.921	Oryzias_latipes_hsok
ENSG00000125351	UPF3B	96	64.455	ENSOMEG00000014736	upf3b	95	54.486	Oryzias_melastigma
ENSG00000125351	UPF3B	95	84.615	ENSOGAG00000033003	-	100	81.957	Otolemur_garnettii
ENSG00000125351	UPF3B	100	95.106	ENSOGAG00000004643	-	100	95.106	Otolemur_garnettii
ENSG00000125351	UPF3B	100	95.267	ENSOARG00000016051	-	100	95.267	Ovis_aries
ENSG00000125351	UPF3B	88	62.176	ENSOARG00000009004	UPF3A	50	64.082	Ovis_aries
ENSG00000125351	UPF3B	90	70.213	ENSOARG00000007869	-	99	67.139	Ovis_aries
ENSG00000125351	UPF3B	100	100.000	ENSPPAG00000040390	UPF3B	100	100.000	Pan_paniscus
ENSG00000125351	UPF3B	76	68.902	ENSPPRG00000025062	UPF3A	55	54.887	Panthera_pardus
ENSG00000125351	UPF3B	100	95.238	ENSPPRG00000023536	UPF3B	100	95.238	Panthera_pardus
ENSG00000125351	UPF3B	96	97.115	ENSPTIG00000015264	UPF3B	100	97.398	Panthera_tigris_altaica
ENSG00000125351	UPF3B	72	54.140	ENSPTRG00000041187	-	50	47.107	Pan_troglodytes
ENSG00000125351	UPF3B	72	54.140	ENSPTRG00000041835	-	51	46.281	Pan_troglodytes
ENSG00000125351	UPF3B	100	100.000	ENSPTRG00000022228	UPF3B	100	100.000	Pan_troglodytes
ENSG00000125351	UPF3B	100	99.793	ENSPANG00000000900	UPF3B	100	100.000	Papio_anubis
ENSG00000125351	UPF3B	93	61.386	ENSPANG00000004346	UPF3A	53	64.032	Papio_anubis
ENSG00000125351	UPF3B	99	70.175	ENSPANG00000029350	-	99	69.298	Papio_anubis
ENSG00000125351	UPF3B	96	68.095	ENSPKIG00000019226	upf3b	93	63.291	Paramormyrops_kingsleyae
ENSG00000125351	UPF3B	53	83.478	ENSPSIG00000005833	UPF3B	85	75.934	Pelodiscus_sinensis
ENSG00000125351	UPF3B	72	71.338	ENSPSIG00000007468	UPF3A	99	52.471	Pelodiscus_sinensis
ENSG00000125351	UPF3B	96	66.507	ENSPMGG00000016067	upf3b	87	72.083	Periophthalmus_magnuspinnatus
ENSG00000125351	UPF3B	96	92.308	ENSPEMG00000012352	Upf3b	100	86.831	Peromyscus_maniculatus_bairdii
ENSG00000125351	UPF3B	88	63.684	ENSPCIG00000019590	-	66	71.333	Phascolarctos_cinereus
ENSG00000125351	UPF3B	93	70.880	ENSPCIG00000028914	UPF3B	92	68.950	Phascolarctos_cinereus
ENSG00000125351	UPF3B	76	68.902	ENSPLAG00000011960	upf3a	83	52.206	Poecilia_latipinna
ENSG00000125351	UPF3B	96	66.507	ENSPLAG00000019922	upf3b	96	56.616	Poecilia_latipinna
ENSG00000125351	UPF3B	96	66.507	ENSPLAG00000005105	upf3b	96	56.616	Poecilia_latipinna
ENSG00000125351	UPF3B	96	66.507	ENSPMEG00000023532	upf3b	96	56.616	Poecilia_mexicana
ENSG00000125351	UPF3B	71	65.161	ENSPREG00000012214	upf3b	95	63.924	Poecilia_reticulata
ENSG00000125351	UPF3B	52	73.451	ENSPREG00000005566	upf3a	66	73.451	Poecilia_reticulata
ENSG00000125351	UPF3B	99	98.131	ENSPPYG00000020675	-	100	100.000	Pongo_abelii
ENSG00000125351	UPF3B	76	69.512	ENSPPYG00000005536	UPF3A	51	63.636	Pongo_abelii
ENSG00000125351	UPF3B	76	51.829	ENSPCAG00000013124	UPF3A	51	52.964	Procavia_capensis
ENSG00000125351	UPF3B	100	92.547	ENSPCAG00000009464	UPF3B	100	92.547	Procavia_capensis
ENSG00000125351	UPF3B	99	97.196	ENSPCOG00000021960	UPF3B	100	98.148	Propithecus_coquereli
ENSG00000125351	UPF3B	76	62.805	ENSPVAG00000005656	UPF3A	59	47.203	Pteropus_vampyrus
ENSG00000125351	UPF3B	100	81.573	ENSPVAG00000014075	UPF3B	100	81.573	Pteropus_vampyrus
ENSG00000125351	UPF3B	96	66.507	ENSPNYG00000009846	upf3b	64	65.798	Pundamilia_nyererei
ENSG00000125351	UPF3B	96	66.029	ENSPNAG00000021528	upf3b	98	56.568	Pygocentrus_nattereri
ENSG00000125351	UPF3B	96	90.385	ENSRNOG00000039994	Upf3b	100	85.773	Rattus_norvegicus
ENSG00000125351	UPF3B	75	68.098	ENSRBIG00000034007	UPF3A	55	64.082	Rhinopithecus_bieti
ENSG00000125351	UPF3B	82	97.481	ENSRBIG00000037219	UPF3B	100	97.481	Rhinopithecus_bieti
ENSG00000125351	UPF3B	72	70.513	ENSRROG00000012212	UPF3A	51	64.082	Rhinopithecus_roxellana
ENSG00000125351	UPF3B	100	100.000	ENSRROG00000041031	UPF3B	100	100.000	Rhinopithecus_roxellana
ENSG00000125351	UPF3B	100	97.723	ENSSBOG00000019740	UPF3B	100	98.513	Saimiri_boliviensis_boliviensis
ENSG00000125351	UPF3B	74	68.125	ENSSHAG00000009895	UPF3A	98	51.636	Sarcophilus_harrisii
ENSG00000125351	UPF3B	87	75.120	ENSSHAG00000008634	UPF3B	99	69.280	Sarcophilus_harrisii
ENSG00000125351	UPF3B	96	69.856	ENSSFOG00015005614	upf3b	100	55.950	Scleropages_formosus
ENSG00000125351	UPF3B	96	68.571	ENSSMAG00000012913	upf3b	84	67.647	Scophthalmus_maximus
ENSG00000125351	UPF3B	74	70.000	ENSSMAG00000003858	upf3a	78	67.241	Scophthalmus_maximus
ENSG00000125351	UPF3B	76	70.732	ENSSDUG00000009680	upf3a	57	76.344	Seriola_dumerili
ENSG00000125351	UPF3B	96	66.667	ENSSDUG00000005682	upf3b	97	52.052	Seriola_dumerili
ENSG00000125351	UPF3B	96	67.143	ENSSLDG00000003130	upf3b	97	56.156	Seriola_lalandi_dorsalis
ENSG00000125351	UPF3B	72	50.000	ENSSARG00000007262	UPF3A	92	36.761	Sorex_araneus
ENSG00000125351	UPF3B	89	85.023	ENSSARG00000004147	UPF3B	100	84.562	Sorex_araneus
ENSG00000125351	UPF3B	99	66.667	ENSSPUG00000013082	UPF3B	99	64.803	Sphenodon_punctatus
ENSG00000125351	UPF3B	96	69.048	ENSSPAG00000009989	upf3b	96	53.478	Stegastes_partitus
ENSG00000125351	UPF3B	76	70.732	ENSSPAG00000007938	upf3a	72	70.701	Stegastes_partitus
ENSG00000125351	UPF3B	93	58.019	ENSSSCG00000024679	UPF3A	66	51.636	Sus_scrofa
ENSG00000125351	UPF3B	100	94.894	ENSSSCG00000012617	UPF3B	100	94.894	Sus_scrofa
ENSG00000125351	UPF3B	76	71.341	ENSTGUG00000009493	UPF3A	99	54.568	Taeniopygia_guttata
ENSG00000125351	UPF3B	89	70.492	ENSTGUG00000003413	UPF3B	99	70.726	Taeniopygia_guttata
ENSG00000125351	UPF3B	74	75.155	ENSTRUG00000010645	upf3b	61	69.767	Takifugu_rubripes
ENSG00000125351	UPF3B	96	65.728	ENSTNIG00000015763	upf3b	56	60.000	Tetraodon_nigroviridis
ENSG00000125351	UPF3B	66	40.367	ENSTBEG00000017186	-	60	42.857	Tupaia_belangeri
ENSG00000125351	UPF3B	100	79.089	ENSTBEG00000003229	UPF3B	100	79.089	Tupaia_belangeri
ENSG00000125351	UPF3B	100	91.314	ENSUAMG00000024565	UPF3B	100	91.949	Ursus_americanus
ENSG00000125351	UPF3B	93	86.638	ENSUMAG00000002150	UPF3B	99	82.900	Ursus_maritimus
ENSG00000125351	UPF3B	85	95.610	ENSVPAG00000009971	UPF3B	100	95.610	Vicugna_pacos
ENSG00000125351	UPF3B	72	69.872	ENSVPAG00000003525	UPF3A	56	58.590	Vicugna_pacos
ENSG00000125351	UPF3B	76	66.667	ENSVVUG00000013538	UPF3A	55	50.000	Vulpes_vulpes
ENSG00000125351	UPF3B	96	96.635	ENSVVUG00000011594	UPF3B	97	96.635	Vulpes_vulpes
ENSG00000125351	UPF3B	88	59.799	ENSXETG00000002572	upf3a	90	46.650	Xenopus_tropicalis
ENSG00000125351	UPF3B	74	81.250	ENSXETG00000007440	upf3b	78	77.778	Xenopus_tropicalis
ENSG00000125351	UPF3B	96	65.566	ENSXCOG00000016586	upf3b	98	65.566	Xiphophorus_couchianus
ENSG00000125351	UPF3B	96	65.072	ENSXMAG00000013680	upf3b	94	56.629	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	16601204.	IDA	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	18369367.	IMP	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	11163187.	NAS	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	TAS	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0003729	mRNA binding	11546873.	IDA	Function
GO:0005515	protein binding	11163187.11546873.11546874.12417715.15231747.15361857.15680326.16209946.16452507.16601204.19410547.19417104.19478851.19503078.19864460.20930030.23084401.23788676.26496610.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005634	nucleus	11163187.	NAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	11163187.	NAS	Component
GO:0005815	microtubule organizing center	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006405	RNA export from nucleus	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0017056	structural constituent of nuclear pore	11163187.	NAS	Function
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0035145	exon-exon junction complex	16601204.	IDA	Component
GO:0035145	exon-exon junction complex	11546873.12718880.	IDA	Component
GO:0045727	positive regulation of translation	21873635.	IBA	Process
GO:0045727	positive regulation of translation	16601204.	IDA	Process