EuRBPDB

Description

Ensembl ID: ENSG00000125484 (Gene tree)
Gene ID: 9329
Gene Symbol: GTF3C4
Alias: TFIIIC90|KAT12
Full Name: general transcription factor IIIC subunit 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 24,921 bases
Position: chr9:132,670,035-132,694,955
Accession: 4667
RBP type: non-canonical RBP
Summary: (General Transcription Factor IIIC Subunit 4) is a Protein Coding gene. Among its related pathways are Transcription of tRNA and RNA Polymerase III Transcription Initiation. Gene Ontology (GO) annotations related to this gene include histone acetyltransferase activity and enzyme activator activity.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000483873	GTF3C4-202	1417	-	ENSP00000431378	149 (aa)	-	F2Z356
ENST00000372146	GTF3C4-201	9043	XM_017015318	ENSP00000361219	822 (aa)	XP_016870807	Q9UKN8

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125484	Schizophrenia	4.12E-5	-

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125484	GTF3C4	100	93.187	ENSMUSG00000035666	Gtf3c4	100	94.830	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000127	transcription factor TFIIIC complex	21873635.	IBA	Component
GO:0000127	transcription factor TFIIIC complex	17409385.	IDA	Component
GO:0003677	DNA binding	17409385.	IC	Function
GO:0004402	histone acetyltransferase activity	-	IEA	Function
GO:0005515	protein binding	17409385.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0006383	transcription by RNA polymerase III	17409385.	IC	Process
GO:0006384	transcription initiation from RNA polymerase III promoter	10523658.	TAS	Process
GO:0008047	enzyme activator activity	10523658.	TAS	Function
GO:0016573	histone acetylation	-	IEA	Process
GO:0042791	5S class rRNA transcription by RNA polymerase III	17409385.	IC	Process
GO:0042797	tRNA transcription by RNA polymerase III	17409385.	IC	Process
GO:0043085	positive regulation of catalytic activity	-	IEA	Process