EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125630 (Gene tree)
Gene ID: 84172
Gene Symbol: POLR1B
Alias: Rpo1-2|FLJ21921|FLJ10816|RPA2
Full Name: RNA polymerase I subunit B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 35,239 bases
Position: chr2:112,541,915-112,577,153
Accession: 20454
RBP type: canonical RBP
Summary: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000394408	RNA_pol_Rpa2_4	PF06883.12	2e-19	1	1
ENSP00000437914	RNA_pol_Rpa2_4	PF06883.12	8e-19	1	1
ENSP00000405358	RNA_pol_Rpa2_4	PF06883.12	8.8e-19	1	1
ENSP00000263331	RNA_pol_Rpa2_4	PF06883.12	9.4e-19	1	1
ENSP00000444136	RNA_pol_Rpa2_4	PF06883.12	9.8e-19	1	1
ENSP00000387143	RNA_pol_Rpa2_4	PF06883.12	1.5e-10	1	1
ENSP00000263331	RNA_pol_Rpb2_1	PF04563.15	9.1e-34	1	1
ENSP00000444136	RNA_pol_Rpb2_1	PF04563.15	9.7e-34	1	1
ENSP00000387143	RNA_pol_Rpb2_1	PF04563.15	1.5e-31	1	1
ENSP00000405358	RNA_pol_Rpb2_1	PF04563.15	5.7e-21	1	1
ENSP00000388577	RNA_pol_Rpb2_1	PF04563.15	1e-08	1	1
ENSP00000415754	RNA_pol_Rpb2_1	PF04563.15	3.5e-06	1	1
ENSP00000387143	RNA_pol_Rpb2_2	PF04561.14	3.7e-12	1	1
ENSP00000405358	RNA_pol_Rpb2_2	PF04561.14	4.5e-12	1	1
ENSP00000263331	RNA_pol_Rpb2_2	PF04561.14	4.9e-12	1	1
ENSP00000444136	RNA_pol_Rpb2_2	PF04561.14	5.2e-12	1	1
ENSP00000437914	RNA_pol_Rpb2_2	PF04561.14	1.6e-11	1	1
ENSP00000437914	RNA_pol_Rpb2_3	PF04565.16	4.6e-27	1	1
ENSP00000405358	RNA_pol_Rpb2_3	PF04565.16	5.5e-27	1	1
ENSP00000263331	RNA_pol_Rpb2_3	PF04565.16	5.8e-27	1	1
ENSP00000444136	RNA_pol_Rpb2_3	PF04565.16	6e-27	1	1
ENSP00000437914	RNA_pol_Rpb2_7	PF04560.20	1.4e-21	1	1
ENSP00000387143	RNA_pol_Rpb2_7	PF04560.20	1.4e-21	1	1
ENSP00000405358	RNA_pol_Rpb2_7	PF04560.20	1.7e-21	1	1
ENSP00000263331	RNA_pol_Rpb2_7	PF04560.20	1.8e-21	1	1
ENSP00000444136	RNA_pol_Rpb2_7	PF04560.20	1.9e-21	1	1
ENSP00000437914	RNA_pol_Rpb2_6	PF00562.28	4e-118	1	1
ENSP00000387143	RNA_pol_Rpb2_6	PF00562.28	4.4e-118	1	1
ENSP00000405358	RNA_pol_Rpb2_6	PF00562.28	6e-118	1	1
ENSP00000263331	RNA_pol_Rpb2_6	PF00562.28	6.8e-118	1	1
ENSP00000444136	RNA_pol_Rpb2_6	PF00562.28	7.3e-118	1	1
ENSP00000394408	RNA_pol_Rpb2_6	PF00562.28	4.7e-58	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18086878	Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription.	Mol Cell Biol	2008 Mar	Beckouet F	-
14555487	Role of second-largest RNA polymerase I subunit Zn-binding domain in enzyme assembly.	Eukaryot Cell	2003 Oct	Naryshkina T	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000430769	POLR1B-207	572	-	ENSP00000415754	114 (aa)	-	C9JJG2
ENST00000424062	POLR1B-205	558	-	ENSP00000390973	92 (aa)	-	F8WBB9
ENST00000458012	POLR1B-210	923	-	ENSP00000394408	307 (aa)	-	H7C0D9
ENST00000496238	POLR1B-214	587	-	-	- (aa)	-	-
ENST00000498054	POLR1B-215	636	-	-	- (aa)	-	-
ENST00000409894	POLR1B-203	4457	-	ENSP00000387143	952 (aa)	-	Q9H9Y6
ENST00000448770	POLR1B-209	2494	-	ENSP00000390274	105 (aa)	-	F8WCS3
ENST00000438748	POLR1B-208	555	-	ENSP00000388577	128 (aa)	-	C9JS83
ENST00000468475	POLR1B-211	569	-	-	- (aa)	-	-
ENST00000263331	POLR1B-201	4558	-	ENSP00000263331	1135 (aa)	-	Q9H9Y6
ENST00000417433	POLR1B-204	3836	-	ENSP00000405358	1079 (aa)	-	Q9H9Y6
ENST00000484574	POLR1B-213	551	-	-	- (aa)	-	-
ENST00000541869	POLR1B-217	5059	-	ENSP00000444136	1173 (aa)	-	Q9H9Y6
ENST00000537335	POLR1B-216	4961	-	ENSP00000437914	924 (aa)	-	Q9H9Y6
ENST00000333990	POLR1B-202	4376	-	ENSP00000334589	73 (aa)	-	F8WAK7
ENST00000430293	POLR1B-206	595	-	ENSP00000403094	65 (aa)	-	F8WDS4
ENST00000475318	POLR1B-212	680	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000125630's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125630	Estradiol	3.1080000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000125630	rs3980078	2	112570466	A	Smoking status (ever vs never smokers)	30643258	[0.01-0.021] unit decrease	0.015629334	EFO_0004318

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125630's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000125630	POLR1B	90	37.079	ENSG00000047315	POLR2B	85	30.147

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125630	POLR1B	99	82.065	ENSAPOG00000000931	polr1b	99	77.072	Acanthochromis_polyacanthus
ENSG00000125630	POLR1B	90	36.704	ENSAPOG00000019678	polr2b	75	36.704	Acanthochromis_polyacanthus
ENSG00000125630	POLR1B	97	30.722	ENSAPOG00000018360	polr3b	98	30.651	Acanthochromis_polyacanthus
ENSG00000125630	POLR1B	90	37.931	ENSAMEG00000016022	POLR3B	96	30.112	Ailuropoda_melanoleuca
ENSG00000125630	POLR1B	90	36.754	ENSAMEG00000008561	POLR2B	75	36.754	Ailuropoda_melanoleuca
ENSG00000125630	POLR1B	99	96.745	ENSAMEG00000010826	POLR1B	100	94.361	Ailuropoda_melanoleuca
ENSG00000125630	POLR1B	99	83.696	ENSACIG00000002290	polr1b	99	77.249	Amphilophus_citrinellus
ENSG00000125630	POLR1B	97	30.896	ENSACIG00000005894	polr3b	98	30.205	Amphilophus_citrinellus
ENSG00000125630	POLR1B	96	30.252	ENSACIG00000009631	POLR2B	85	30.252	Amphilophus_citrinellus
ENSG00000125630	POLR1B	90	36.891	ENSAOCG00000005752	polr2b	76	36.381	Amphiprion_ocellaris
ENSG00000125630	POLR1B	99	83.152	ENSAOCG00000004249	polr1b	99	77.072	Amphiprion_ocellaris
ENSG00000125630	POLR1B	97	30.722	ENSAOCG00000010619	polr3b	98	30.000	Amphiprion_ocellaris
ENSG00000125630	POLR1B	99	82.971	ENSAPEG00000004971	polr1b	99	77.160	Amphiprion_percula
ENSG00000125630	POLR1B	97	30.517	ENSAPEG00000006829	polr3b	93	30.563	Amphiprion_percula
ENSG00000125630	POLR1B	90	36.891	ENSAPEG00000005116	polr2b	75	36.891	Amphiprion_percula
ENSG00000125630	POLR1B	97	30.650	ENSATEG00000021713	polr3b	98	30.000	Anabas_testudineus
ENSG00000125630	POLR1B	99	84.058	ENSATEG00000010957	polr1b	99	77.160	Anabas_testudineus
ENSG00000125630	POLR1B	90	37.079	ENSATEG00000019461	polr2b	75	37.079	Anabas_testudineus
ENSG00000125630	POLR1B	99	78.049	ENSAPLG00000004142	POLR1B	99	73.641	Anas_platyrhynchos
ENSG00000125630	POLR1B	90	37.833	ENSAPLG00000005305	POLR3B	91	30.157	Anas_platyrhynchos
ENSG00000125630	POLR1B	96	30.640	ENSAPLG00000009560	POLR2B	78	30.640	Anas_platyrhynchos
ENSG00000125630	POLR1B	96	30.147	ENSACAG00000002123	POLR2B	77	30.147	Anolis_carolinensis
ENSG00000125630	POLR1B	100	67.544	ENSACAG00000005660	POLR1B	99	73.413	Anolis_carolinensis
ENSG00000125630	POLR1B	99	84.390	ENSACAG00000007117	-	99	83.068	Anolis_carolinensis
ENSG00000125630	POLR1B	97	30.703	ENSACAG00000015400	POLR3B	96	30.703	Anolis_carolinensis
ENSG00000125630	POLR1B	90	37.079	ENSANAG00000024663	POLR2B	82	30.147	Aotus_nancymaae
ENSG00000125630	POLR1B	100	98.006	ENSANAG00000026201	POLR1B	100	98.006	Aotus_nancymaae
ENSG00000125630	POLR1B	90	38.123	ENSANAG00000036735	POLR3B	99	30.120	Aotus_nancymaae
ENSG00000125630	POLR1B	97	30.896	ENSACLG00000027243	polr3b	96	30.163	Astatotilapia_calliptera
ENSG00000125630	POLR1B	96	30.252	ENSACLG00000018568	polr2b	81	30.252	Astatotilapia_calliptera
ENSG00000125630	POLR1B	99	83.152	ENSACLG00000019089	polr1b	99	76.720	Astatotilapia_calliptera
ENSG00000125630	POLR1B	99	84.783	ENSAMXG00000037818	polr1b	99	77.337	Astyanax_mexicanus
ENSG00000125630	POLR1B	97	30.619	ENSAMXG00000020163	polr3b	96	30.017	Astyanax_mexicanus
ENSG00000125630	POLR1B	96	30.494	ENSAMXG00000004040	POLR2B	80	37.453	Astyanax_mexicanus
ENSG00000125630	POLR1B	90	37.931	ENSBTAG00000004781	POLR3B	96	30.371	Bos_taurus
ENSG00000125630	POLR1B	90	36.891	ENSBTAG00000019366	POLR2B	90	30.284	Bos_taurus
ENSG00000125630	POLR1B	99	95.479	ENSBTAG00000014166	POLR1B	100	93.744	Bos_taurus
ENSG00000125630	POLR1B	68	36.685	WBGene00016140	rpb-2	56	36.685	Caenorhabditis_elegans
ENSG00000125630	POLR1B	91	36.477	WBGene00017300	rpc-2	88	30.018	Caenorhabditis_elegans
ENSG00000125630	POLR1B	95	51.413	WBGene00008781	rpoa-2	99	45.536	Caenorhabditis_elegans
ENSG00000125630	POLR1B	90	37.079	ENSCJAG00000004118	POLR2B	82	30.147	Callithrix_jacchus
ENSG00000125630	POLR1B	99	99.512	ENSCJAG00000016433	POLR1B	99	99.096	Callithrix_jacchus
ENSG00000125630	POLR1B	90	38.123	ENSCJAG00000014985	POLR3B	96	30.198	Callithrix_jacchus
ENSG00000125630	POLR1B	90	37.931	ENSCAFG00000001851	POLR3B	96	30.371	Canis_familiaris
ENSG00000125630	POLR1B	99	96.203	ENSCAFG00000007174	POLR1B	100	93.833	Canis_familiaris
ENSG00000125630	POLR1B	90	36.891	ENSCAFG00000002296	POLR2B	75	36.891	Canis_familiaris
ENSG00000125630	POLR1B	96	30.932	ENSCAFG00020005062	POLR3B	99	30.790	Canis_lupus_dingo
ENSG00000125630	POLR1B	90	36.891	ENSCAFG00020027317	POLR2B	75	36.891	Canis_lupus_dingo
ENSG00000125630	POLR1B	99	96.203	ENSCAFG00020017367	POLR1B	99	93.921	Canis_lupus_dingo
ENSG00000125630	POLR1B	90	37.931	ENSCHIG00000015728	POLR3B	96	30.112	Capra_hircus
ENSG00000125630	POLR1B	99	95.841	ENSCHIG00000014527	POLR1B	100	93.480	Capra_hircus
ENSG00000125630	POLR1B	90	36.891	ENSCHIG00000011013	POLR2B	75	36.891	Capra_hircus
ENSG00000125630	POLR1B	100	94.538	ENSTSYG00000003669	POLR1B	100	94.538	Carlito_syrichta
ENSG00000125630	POLR1B	90	37.079	ENSTSYG00000006881	POLR2B	82	30.147	Carlito_syrichta
ENSG00000125630	POLR1B	90	37.931	ENSTSYG00000014075	POLR3B	96	30.356	Carlito_syrichta
ENSG00000125630	POLR1B	90	35.206	ENSCAPG00000013855	POLR2B	76	35.206	Cavia_aperea
ENSG00000125630	POLR1B	82	37.277	ENSCAPG00000007351	POLR3B	70	37.277	Cavia_aperea
ENSG00000125630	POLR1B	95	94.974	ENSCAPG00000012821	POLR1B	85	94.974	Cavia_aperea
ENSG00000125630	POLR1B	84	37.277	ENSCPOG00000004891	POLR3B	70	37.277	Cavia_porcellus
ENSG00000125630	POLR1B	99	94.575	ENSCPOG00000015744	POLR1B	100	91.278	Cavia_porcellus
ENSG00000125630	POLR1B	90	37.079	ENSCPOG00000013006	POLR2B	75	37.079	Cavia_porcellus
ENSG00000125630	POLR1B	90	38.123	ENSCCAG00000029080	POLR3B	96	30.198	Cebus_capucinus
ENSG00000125630	POLR1B	99	99.512	ENSCCAG00000035252	POLR1B	99	99.277	Cebus_capucinus
ENSG00000125630	POLR1B	90	37.079	ENSCCAG00000025655	POLR2B	75	37.079	Cebus_capucinus
ENSG00000125630	POLR1B	90	37.931	ENSCATG00000035334	POLR3B	93	33.383	Cercocebus_atys
ENSG00000125630	POLR1B	90	37.079	ENSCATG00000037194	POLR2B	82	30.147	Cercocebus_atys
ENSG00000125630	POLR1B	100	99.026	ENSCATG00000037382	POLR1B	100	98.888	Cercocebus_atys
ENSG00000125630	POLR1B	91	38.580	ENSCLAG00000012996	POLR3B	98	30.424	Chinchilla_lanigera
ENSG00000125630	POLR1B	99	95.298	ENSCLAG00000004899	POLR1B	100	91.806	Chinchilla_lanigera
ENSG00000125630	POLR1B	90	37.079	ENSCLAG00000005440	POLR2B	75	37.079	Chinchilla_lanigera
ENSG00000125630	POLR1B	83	30.403	ENSCSAG00000002957	POLR3B	95	30.287	Chlorocebus_sabaeus
ENSG00000125630	POLR1B	90	37.079	ENSCSAG00000005130	POLR2B	76	37.079	Chlorocebus_sabaeus
ENSG00000125630	POLR1B	100	99.026	ENSCSAG00000016783	POLR1B	100	98.678	Chlorocebus_sabaeus
ENSG00000125630	POLR1B	99	95.122	ENSCHOG00000007229	POLR1B	100	90.731	Choloepus_hoffmanni
ENSG00000125630	POLR1B	97	31.348	ENSCPBG00000023199	POLR3B	96	30.903	Chrysemys_picta_bellii
ENSG00000125630	POLR1B	96	30.147	ENSCPBG00000015003	POLR2B	77	30.147	Chrysemys_picta_bellii
ENSG00000125630	POLR1B	99	88.293	ENSCPBG00000003962	POLR1B	99	92.026	Chrysemys_picta_bellii
ENSG00000125630	POLR1B	90	36.929	ENSCING00000006386	-	76	36.929	Ciona_intestinalis
ENSG00000125630	POLR1B	99	56.711	ENSCING00000003329	-	99	52.967	Ciona_intestinalis
ENSG00000125630	POLR1B	97	30.112	ENSCSAVG00000007982	-	98	30.112	Ciona_savignyi
ENSG00000125630	POLR1B	94	41.259	ENSCSAVG00000000129	-	87	41.259	Ciona_savignyi
ENSG00000125630	POLR1B	90	37.079	ENSCANG00000041857	POLR2B	75	37.079	Colobus_angolensis_palliatus
ENSG00000125630	POLR1B	90	37.931	ENSCANG00000041067	POLR3B	96	30.112	Colobus_angolensis_palliatus
ENSG00000125630	POLR1B	100	98.529	ENSCANG00000039531	POLR1B	100	98.529	Colobus_angolensis_palliatus
ENSG00000125630	POLR1B	90	38.050	ENSCGRG00001013651	Polr3b	96	30.589	Cricetulus_griseus_chok1gshd
ENSG00000125630	POLR1B	90	37.079	ENSCGRG00001021842	Polr2b	75	37.079	Cricetulus_griseus_chok1gshd
ENSG00000125630	POLR1B	99	94.937	ENSCGRG00001014254	Polr1b	100	90.925	Cricetulus_griseus_chok1gshd
ENSG00000125630	POLR1B	90	38.050	ENSCGRG00000001263	Polr3b	96	30.589	Cricetulus_griseus_crigri
ENSG00000125630	POLR1B	99	94.937	ENSCGRG00000017847	Polr1b	100	91.013	Cricetulus_griseus_crigri
ENSG00000125630	POLR1B	90	37.079	ENSCGRG00000012547	Polr2b	75	37.079	Cricetulus_griseus_crigri
ENSG00000125630	POLR1B	90	36.891	ENSCSEG00000005318	polr2b	75	36.891	Cynoglossus_semilaevis
ENSG00000125630	POLR1B	90	37.523	ENSCSEG00000005922	polr3b	96	30.129	Cynoglossus_semilaevis
ENSG00000125630	POLR1B	99	82.428	ENSCSEG00000008564	polr1b	99	74.780	Cynoglossus_semilaevis
ENSG00000125630	POLR1B	90	37.079	ENSCVAG00000007676	polr2b	75	37.079	Cyprinodon_variegatus
ENSG00000125630	POLR1B	97	31.102	ENSCVAG00000006557	polr3b	96	30.506	Cyprinodon_variegatus
ENSG00000125630	POLR1B	99	83.877	ENSCVAG00000005824	polr1b	99	77.249	Cyprinodon_variegatus
ENSG00000125630	POLR1B	99	83.514	ENSDARG00000077469	polr1b	99	75.841	Danio_rerio
ENSG00000125630	POLR1B	90	36.891	ENSDARG00000098783	polr2b	75	36.891	Danio_rerio
ENSG00000125630	POLR1B	90	37.853	ENSDARG00000062915	polr3b	96	30.334	Danio_rerio
ENSG00000125630	POLR1B	90	38.123	ENSDNOG00000001806	POLR3B	89	30.345	Dasypus_novemcinctus
ENSG00000125630	POLR1B	90	37.079	ENSDNOG00000007705	POLR2B	75	37.079	Dasypus_novemcinctus
ENSG00000125630	POLR1B	100	91.775	ENSDNOG00000017718	POLR1B	98	91.454	Dasypus_novemcinctus
ENSG00000125630	POLR1B	78	37.288	ENSDORG00000010077	Polr2b	72	37.288	Dipodomys_ordii
ENSG00000125630	POLR1B	99	94.756	ENSDORG00000014309	Polr1b	100	91.630	Dipodomys_ordii
ENSG00000125630	POLR1B	90	37.931	ENSDORG00000013345	Polr3b	96	30.112	Dipodomys_ordii
ENSG00000125630	POLR1B	97	52.405	FBgn0003278	RpI135	98	45.568	Drosophila_melanogaster
ENSG00000125630	POLR1B	90	36.989	FBgn0262955	RpII140	75	36.989	Drosophila_melanogaster
ENSG00000125630	POLR1B	94	37.870	FBgn0004463	RpIII128	87	30.312	Drosophila_melanogaster
ENSG00000125630	POLR1B	88	37.066	ENSETEG00000011734	POLR2B	75	37.066	Echinops_telfairi
ENSG00000125630	POLR1B	79	32.478	ENSETEG00000017715	POLR3B	69	32.478	Echinops_telfairi
ENSG00000125630	POLR1B	99	94.146	ENSETEG00000004001	POLR1B	89	93.052	Echinops_telfairi
ENSG00000125630	POLR1B	90	36.900	ENSEBUG00000010593	-	75	36.900	Eptatretus_burgeri
ENSG00000125630	POLR1B	90	34.559	ENSEBUG00000003813	-	76	34.559	Eptatretus_burgeri
ENSG00000125630	POLR1B	96	31.663	ENSEBUG00000010186	-	85	31.663	Eptatretus_burgeri
ENSG00000125630	POLR1B	74	78.750	ENSEBUG00000015791	polr1b	99	60.175	Eptatretus_burgeri
ENSG00000125630	POLR1B	99	96.745	ENSEASG00005006504	POLR1B	100	93.833	Equus_asinus_asinus
ENSG00000125630	POLR1B	88	42.213	ENSEASG00005021189	POLR3B	93	42.213	Equus_asinus_asinus
ENSG00000125630	POLR1B	90	37.079	ENSEASG00005017727	POLR2B	75	37.079	Equus_asinus_asinus
ENSG00000125630	POLR1B	90	37.079	ENSECAG00000013610	POLR2B	75	37.079	Equus_caballus
ENSG00000125630	POLR1B	99	96.926	ENSECAG00000010062	POLR1B	100	94.009	Equus_caballus
ENSG00000125630	POLR1B	90	37.931	ENSECAG00000019086	POLR3B	96	30.371	Equus_caballus
ENSG00000125630	POLR1B	76	36.000	ENSEEUG00000009798	POLR2B	75	36.000	Erinaceus_europaeus
ENSG00000125630	POLR1B	77	97.674	ENSEEUG00000004559	-	80	96.928	Erinaceus_europaeus
ENSG00000125630	POLR1B	97	31.399	ENSELUG00000023988	polr3b	95	31.426	Esox_lucius
ENSG00000125630	POLR1B	86	37.941	ENSELUG00000023372	polr2b	62	37.941	Esox_lucius
ENSG00000125630	POLR1B	99	83.877	ENSELUG00000019627	polr1b	99	77.160	Esox_lucius
ENSG00000125630	POLR1B	90	37.931	ENSFCAG00000015617	POLR3B	96	30.112	Felis_catus
ENSG00000125630	POLR1B	90	36.891	ENSFCAG00000003905	POLR2B	82	30.042	Felis_catus
ENSG00000125630	POLR1B	99	96.022	ENSFCAG00000008091	POLR1B	99	96.022	Felis_catus
ENSG00000125630	POLR1B	90	37.833	ENSFALG00000013416	POLR3B	96	30.829	Ficedula_albicollis
ENSG00000125630	POLR1B	99	76.585	ENSFALG00000000717	POLR1B	99	74.206	Ficedula_albicollis
ENSG00000125630	POLR1B	90	37.828	ENSFALG00000005896	POLR2B	88	30.000	Ficedula_albicollis
ENSG00000125630	POLR1B	99	94.575	ENSFDAG00000020976	POLR1B	100	91.278	Fukomys_damarensis
ENSG00000125630	POLR1B	90	38.623	ENSFDAG00000008736	POLR3B	97	30.282	Fukomys_damarensis
ENSG00000125630	POLR1B	90	37.079	ENSFDAG00000006083	POLR2B	75	37.079	Fukomys_damarensis
ENSG00000125630	POLR1B	61	31.679	ENSFHEG00000015503	polr2b	67	31.679	Fundulus_heteroclitus
ENSG00000125630	POLR1B	73	41.156	ENSFHEG00000008215	polr3b	75	41.156	Fundulus_heteroclitus
ENSG00000125630	POLR1B	85	83.204	ENSFHEG00000000533	polr1b	99	61.727	Fundulus_heteroclitus
ENSG00000125630	POLR1B	97	31.308	ENSGMOG00000004212	polr3b	96	30.532	Gadus_morhua
ENSG00000125630	POLR1B	99	74.634	ENSGMOG00000005847	polr1b	100	68.073	Gadus_morhua
ENSG00000125630	POLR1B	98	30.231	ENSGALG00000012655	POLR3B	99	30.231	Gallus_gallus
ENSG00000125630	POLR1B	96	30.672	ENSGALG00000011387	POLR2B	77	30.672	Gallus_gallus
ENSG00000125630	POLR1B	99	76.585	ENSGALG00000032273	POLR1B	96	73.885	Gallus_gallus
ENSG00000125630	POLR1B	97	30.412	ENSGAFG00000007066	polr3b	90	30.092	Gambusia_affinis
ENSG00000125630	POLR1B	99	82.065	ENSGAFG00000001383	polr1b	99	76.190	Gambusia_affinis
ENSG00000125630	POLR1B	97	30.935	ENSGACG00000011794	polr3b	97	30.231	Gasterosteus_aculeatus
ENSG00000125630	POLR1B	99	82.428	ENSGACG00000003012	polr1b	99	75.088	Gasterosteus_aculeatus
ENSG00000125630	POLR1B	90	37.079	ENSGACG00000016234	polr2b	75	37.079	Gasterosteus_aculeatus
ENSG00000125630	POLR1B	96	30.147	ENSGAGG00000013947	POLR2B	77	30.147	Gopherus_agassizii
ENSG00000125630	POLR1B	97	89.855	ENSGAGG00000016312	POLR1B	99	85.528	Gopherus_agassizii
ENSG00000125630	POLR1B	97	31.303	ENSGAGG00000014364	POLR3B	96	30.087	Gopherus_agassizii
ENSG00000125630	POLR1B	90	37.931	ENSGGOG00000016608	POLR3B	96	30.404	Gorilla_gorilla
ENSG00000125630	POLR1B	100	100.000	ENSGGOG00000013494	POLR1B	100	99.685	Gorilla_gorilla
ENSG00000125630	POLR1B	90	37.079	ENSGGOG00000034986	POLR2B	82	30.147	Gorilla_gorilla
ENSG00000125630	POLR1B	96	30.252	ENSHBUG00000017475	POLR2B	85	30.252	Haplochromis_burtoni
ENSG00000125630	POLR1B	99	83.152	ENSHBUG00000012650	polr1b	99	76.720	Haplochromis_burtoni
ENSG00000125630	POLR1B	90	37.079	ENSHGLG00000011712	POLR2B	75	37.079	Heterocephalus_glaber_female
ENSG00000125630	POLR1B	91	38.432	ENSHGLG00000008833	POLR3B	99	30.085	Heterocephalus_glaber_female
ENSG00000125630	POLR1B	99	93.852	ENSHGLG00000011497	POLR1B	100	91.101	Heterocephalus_glaber_female
ENSG00000125630	POLR1B	90	38.113	ENSHGLG00100015575	POLR2B	87	30.019	Heterocephalus_glaber_male
ENSG00000125630	POLR1B	99	93.852	ENSHGLG00100009371	POLR1B	100	90.044	Heterocephalus_glaber_male
ENSG00000125630	POLR1B	91	38.432	ENSHGLG00100004659	POLR3B	99	30.446	Heterocephalus_glaber_male
ENSG00000125630	POLR1B	97	30.722	ENSHCOG00000006817	polr3b	96	30.189	Hippocampus_comes
ENSG00000125630	POLR1B	90	37.079	ENSHCOG00000013588	polr2b	75	37.079	Hippocampus_comes
ENSG00000125630	POLR1B	99	81.341	ENSHCOG00000000709	polr1b	99	72.575	Hippocampus_comes
ENSG00000125630	POLR1B	90	38.050	ENSIPUG00000016720	Polr3b	96	31.028	Ictalurus_punctatus
ENSG00000125630	POLR1B	99	83.696	ENSIPUG00000018216	polr1b	99	76.631	Ictalurus_punctatus
ENSG00000125630	POLR1B	90	37.453	ENSIPUG00000015595	POLR2B	75	37.453	Ictalurus_punctatus
ENSG00000125630	POLR1B	90	37.931	ENSSTOG00000011849	POLR3B	96	30.112	Ictidomys_tridecemlineatus
ENSG00000125630	POLR1B	100	93.290	ENSSTOG00000008160	POLR1B	99	93.023	Ictidomys_tridecemlineatus
ENSG00000125630	POLR1B	90	37.079	ENSSTOG00000003815	POLR2B	75	37.079	Ictidomys_tridecemlineatus
ENSG00000125630	POLR1B	92	36.757	ENSJJAG00000016101	Polr2b	94	36.757	Jaculus_jaculus
ENSG00000125630	POLR1B	90	37.859	ENSJJAG00000022575	Polr3b	96	30.371	Jaculus_jaculus
ENSG00000125630	POLR1B	100	84.670	ENSJJAG00000000143	Polr1b	100	84.670	Jaculus_jaculus
ENSG00000125630	POLR1B	97	30.412	ENSKMAG00000005022	polr3b	91	30.000	Kryptolebias_marmoratus
ENSG00000125630	POLR1B	90	37.079	ENSKMAG00000017891	polr2b	75	37.079	Kryptolebias_marmoratus
ENSG00000125630	POLR1B	99	81.522	ENSKMAG00000016037	polr1b	99	75.220	Kryptolebias_marmoratus
ENSG00000125630	POLR1B	90	38.086	ENSLBEG00000025800	polr3b	97	30.274	Labrus_bergylta
ENSG00000125630	POLR1B	99	81.884	ENSLBEG00000027396	polr1b	99	73.633	Labrus_bergylta
ENSG00000125630	POLR1B	97	30.761	ENSLACG00000017054	POLR3B	96	30.077	Latimeria_chalumnae
ENSG00000125630	POLR1B	99	87.319	ENSLACG00000009481	POLR1B	99	80.688	Latimeria_chalumnae
ENSG00000125630	POLR1B	90	37.687	ENSLACG00000002956	POLR2B	88	30.046	Latimeria_chalumnae
ENSG00000125630	POLR1B	97	31.095	ENSLOCG00000015249	polr3b	96	30.412	Lepisosteus_oculatus
ENSG00000125630	POLR1B	90	37.079	ENSLOCG00000011424	polr2b	77	30.252	Lepisosteus_oculatus
ENSG00000125630	POLR1B	99	86.829	ENSLOCG00000016558	polr1b	99	78.896	Lepisosteus_oculatus
ENSG00000125630	POLR1B	99	96.390	ENSLAFG00000007659	POLR1B	99	96.390	Loxodonta_africana
ENSG00000125630	POLR1B	96	30.147	ENSLAFG00000003198	POLR2B	97	30.147	Loxodonta_africana
ENSG00000125630	POLR1B	96	31.104	ENSLAFG00000001633	POLR3B	91	30.783	Loxodonta_africana
ENSG00000125630	POLR1B	100	99.026	ENSMFAG00000032912	POLR1B	100	98.845	Macaca_fascicularis
ENSG00000125630	POLR1B	90	37.931	ENSMFAG00000038425	POLR3B	95	33.333	Macaca_fascicularis
ENSG00000125630	POLR1B	90	37.079	ENSMFAG00000042250	POLR2B	82	30.147	Macaca_fascicularis
ENSG00000125630	POLR1B	90	37.931	ENSMMUG00000005208	POLR3B	96	30.112	Macaca_mulatta
ENSG00000125630	POLR1B	100	99.026	ENSMMUG00000009468	POLR1B	100	98.845	Macaca_mulatta
ENSG00000125630	POLR1B	90	37.079	ENSMMUG00000014008	POLR2B	83	30.147	Macaca_mulatta
ENSG00000125630	POLR1B	90	37.079	ENSMNEG00000041844	POLR2B	82	30.147	Macaca_nemestrina
ENSG00000125630	POLR1B	100	98.593	ENSMNEG00000036047	POLR1B	100	98.529	Macaca_nemestrina
ENSG00000125630	POLR1B	90	37.931	ENSMNEG00000044393	POLR3B	96	30.112	Macaca_nemestrina
ENSG00000125630	POLR1B	90	37.931	ENSMLEG00000029122	POLR3B	96	30.112	Mandrillus_leucophaeus
ENSG00000125630	POLR1B	100	99.134	ENSMLEG00000030588	POLR1B	100	99.134	Mandrillus_leucophaeus
ENSG00000125630	POLR1B	90	37.079	ENSMLEG00000038867	POLR2B	76	37.079	Mandrillus_leucophaeus
ENSG00000125630	POLR1B	97	30.825	ENSMAMG00000006251	polr3b	96	30.274	Mastacembelus_armatus
ENSG00000125630	POLR1B	99	83.877	ENSMAMG00000013118	polr1b	99	76.808	Mastacembelus_armatus
ENSG00000125630	POLR1B	90	37.079	ENSMAMG00000014721	polr2b	75	37.079	Mastacembelus_armatus
ENSG00000125630	POLR1B	90	37.079	ENSMZEG00005022118	polr2b	75	37.079	Maylandia_zebra
ENSG00000125630	POLR1B	88	35.771	ENSMZEG00005018987	polr3b	96	30.658	Maylandia_zebra
ENSG00000125630	POLR1B	99	83.152	ENSMZEG00005011850	polr1b	99	76.720	Maylandia_zebra
ENSG00000125630	POLR1B	99	76.098	ENSMGAG00000007074	POLR1B	99	74.423	Meleagris_gallopavo
ENSG00000125630	POLR1B	62	40.000	ENSMGAG00000008481	POLR2B	52	40.000	Meleagris_gallopavo
ENSG00000125630	POLR1B	90	38.123	ENSMAUG00000010200	Polr3b	96	30.285	Mesocricetus_auratus
ENSG00000125630	POLR1B	90	37.079	ENSMAUG00000017655	Polr2b	75	37.079	Mesocricetus_auratus
ENSG00000125630	POLR1B	100	85.965	ENSMAUG00000010593	Polr1b	97	88.517	Mesocricetus_auratus
ENSG00000125630	POLR1B	99	96.203	ENSMICG00000013245	POLR1B	100	94.626	Microcebus_murinus
ENSG00000125630	POLR1B	91	37.931	ENSMICG00000008910	POLR3B	98	30.060	Microcebus_murinus
ENSG00000125630	POLR1B	68	35.821	ENSMICG00000015166	POLR2B	97	37.673	Microcebus_murinus
ENSG00000125630	POLR1B	90	38.050	ENSMOCG00000022129	Polr3b	96	30.285	Microtus_ochrogaster
ENSG00000125630	POLR1B	90	37.079	ENSMOCG00000022645	Polr2b	75	37.079	Microtus_ochrogaster
ENSG00000125630	POLR1B	99	95.298	ENSMOCG00000005942	Polr1b	100	91.454	Microtus_ochrogaster
ENSG00000125630	POLR1B	96	30.252	ENSMMOG00000004329	POLR2B	85	30.252	Mola_mola
ENSG00000125630	POLR1B	99	82.971	ENSMMOG00000008388	polr1b	99	75.330	Mola_mola
ENSG00000125630	POLR1B	97	30.619	ENSMMOG00000017047	polr3b	96	30.017	Mola_mola
ENSG00000125630	POLR1B	90	37.931	ENSMODG00000001884	POLR3B	96	30.277	Monodelphis_domestica
ENSG00000125630	POLR1B	99	91.863	ENSMODG00000006573	POLR1B	100	86.872	Monodelphis_domestica
ENSG00000125630	POLR1B	96	30.147	ENSMODG00000020704	POLR2B	77	30.147	Monodelphis_domestica
ENSG00000125630	POLR1B	90	37.079	ENSMALG00000019597	polr2b	75	37.079	Monopterus_albus
ENSG00000125630	POLR1B	90	37.899	ENSMALG00000003950	polr3b	96	30.189	Monopterus_albus
ENSG00000125630	POLR1B	99	83.514	ENSMALG00000008958	polr1b	99	74.780	Monopterus_albus
ENSG00000125630	POLR1B	99	92.683	MGP_CAROLIEiJ_G0024281	Polr1b	100	90.816	Mus_caroli
ENSG00000125630	POLR1B	90	38.050	MGP_CAROLIEiJ_G0015677	Polr3b	96	30.285	Mus_caroli
ENSG00000125630	POLR1B	90	37.079	MGP_CAROLIEiJ_G0027329	Polr2b	75	37.079	Mus_caroli
ENSG00000125630	POLR1B	90	37.079	ENSMUSG00000029250	Polr2b	75	37.079	Mus_musculus
ENSG00000125630	POLR1B	90	38.050	ENSMUSG00000034453	Polr3b	96	30.285	Mus_musculus
ENSG00000125630	POLR1B	99	94.213	ENSMUSG00000027395	Polr1b	100	90.308	Mus_musculus
ENSG00000125630	POLR1B	90	38.050	MGP_PahariEiJ_G0031407	Polr3b	88	38.050	Mus_pahari
ENSG00000125630	POLR1B	99	93.852	MGP_PahariEiJ_G0025726	Polr1b	100	90.220	Mus_pahari
ENSG00000125630	POLR1B	90	37.079	MGP_PahariEiJ_G0017110	Polr2b	75	37.079	Mus_pahari
ENSG00000125630	POLR1B	90	37.079	MGP_SPRETEiJ_G0028324	Polr2b	75	37.079	Mus_spretus
ENSG00000125630	POLR1B	90	38.050	MGP_SPRETEiJ_G0016495	Polr3b	96	30.285	Mus_spretus
ENSG00000125630	POLR1B	99	94.756	MGP_SPRETEiJ_G0025201	Polr1b	100	90.573	Mus_spretus
ENSG00000125630	POLR1B	90	37.931	ENSMPUG00000012138	POLR3B	96	30.431	Mustela_putorius_furo
ENSG00000125630	POLR1B	90	36.891	ENSMPUG00000004698	POLR2B	75	36.891	Mustela_putorius_furo
ENSG00000125630	POLR1B	99	92.746	ENSMPUG00000009644	POLR1B	99	87.940	Mustela_putorius_furo
ENSG00000125630	POLR1B	96	30.599	ENSMLUG00000028716	-	75	36.517	Myotis_lucifugus
ENSG00000125630	POLR1B	90	37.989	ENSMLUG00000026319	-	87	30.157	Myotis_lucifugus
ENSG00000125630	POLR1B	90	37.643	ENSMLUG00000016235	POLR3B	96	30.207	Myotis_lucifugus
ENSG00000125630	POLR1B	99	95.298	ENSMLUG00000004910	POLR1B	100	92.436	Myotis_lucifugus
ENSG00000125630	POLR1B	90	37.009	ENSMLUG00000016746	-	75	37.009	Myotis_lucifugus
ENSG00000125630	POLR1B	90	38.123	ENSNGAG00000011308	Polr3b	96	30.198	Nannospalax_galili
ENSG00000125630	POLR1B	90	37.079	ENSNGAG00000014884	Polr2b	75	37.079	Nannospalax_galili
ENSG00000125630	POLR1B	99	95.298	ENSNGAG00000021472	Polr1b	100	92.335	Nannospalax_galili
ENSG00000125630	POLR1B	90	37.640	ENSNBRG00000001235	polr2b	75	37.640	Neolamprologus_brichardi
ENSG00000125630	POLR1B	88	35.178	ENSNBRG00000003392	polr3b	72	35.178	Neolamprologus_brichardi
ENSG00000125630	POLR1B	99	83.152	ENSNBRG00000017979	polr1b	99	76.631	Neolamprologus_brichardi
ENSG00000125630	POLR1B	99	100.000	ENSNLEG00000001656	POLR1B	100	98.950	Nomascus_leucogenys
ENSG00000125630	POLR1B	90	37.931	ENSNLEG00000006659	POLR3B	96	30.112	Nomascus_leucogenys
ENSG00000125630	POLR1B	90	37.079	ENSNLEG00000008874	POLR2B	76	37.079	Nomascus_leucogenys
ENSG00000125630	POLR1B	74	30.506	ENSMEUG00000002576	POLR3B	62	30.340	Notamacropus_eugenii
ENSG00000125630	POLR1B	99	88.780	ENSMEUG00000013915	POLR1B	75	95.455	Notamacropus_eugenii
ENSG00000125630	POLR1B	99	93.309	ENSOPRG00000012742	POLR1B	100	91.101	Ochotona_princeps
ENSG00000125630	POLR1B	90	37.453	ENSOPRG00000008124	POLR2B	75	37.453	Ochotona_princeps
ENSG00000125630	POLR1B	77	38.462	ENSOPRG00000008568	POLR3B	77	38.462	Ochotona_princeps
ENSG00000125630	POLR1B	90	37.931	ENSODEG00000012948	POLR3B	97	30.215	Octodon_degus
ENSG00000125630	POLR1B	100	84.211	ENSODEG00000005501	POLR1B	100	83.612	Octodon_degus
ENSG00000125630	POLR1B	90	37.079	ENSODEG00000009625	POLR2B	75	37.079	Octodon_degus
ENSG00000125630	POLR1B	90	37.079	ENSONIG00000000070	polr2b	75	37.079	Oreochromis_niloticus
ENSG00000125630	POLR1B	97	30.896	ENSONIG00000014743	polr3b	99	30.644	Oreochromis_niloticus
ENSG00000125630	POLR1B	99	83.514	ENSONIG00000010382	polr1b	99	76.720	Oreochromis_niloticus
ENSG00000125630	POLR1B	90	38.123	ENSOANG00000005536	POLR3B	98	30.198	Ornithorhynchus_anatinus
ENSG00000125630	POLR1B	100	86.472	ENSOANG00000003621	POLR1B	99	86.463	Ornithorhynchus_anatinus
ENSG00000125630	POLR1B	90	37.931	ENSOCUG00000000884	POLR3B	96	30.285	Oryctolagus_cuniculus
ENSG00000125630	POLR1B	99	94.937	ENSOCUG00000006058	POLR1B	100	93.128	Oryctolagus_cuniculus
ENSG00000125630	POLR1B	90	36.891	ENSOCUG00000016353	POLR2B	75	36.891	Oryctolagus_cuniculus
ENSG00000125630	POLR1B	90	36.891	ENSORLG00000020579	polr2b	75	36.891	Oryzias_latipes
ENSG00000125630	POLR1B	99	81.884	ENSORLG00000000890	polr1b	99	75.419	Oryzias_latipes
ENSG00000125630	POLR1B	97	31.070	ENSORLG00000011064	polr3b	96	30.479	Oryzias_latipes
ENSG00000125630	POLR1B	97	30.967	ENSORLG00020021474	polr3b	96	30.394	Oryzias_latipes_hni
ENSG00000125630	POLR1B	90	36.891	ENSORLG00020008683	polr2b	75	36.891	Oryzias_latipes_hni
ENSG00000125630	POLR1B	99	82.065	ENSORLG00015011105	polr1b	99	75.507	Oryzias_latipes_hsok
ENSG00000125630	POLR1B	90	36.891	ENSORLG00015017748	polr2b	75	36.891	Oryzias_latipes_hsok
ENSG00000125630	POLR1B	97	30.967	ENSORLG00015012016	polr3b	98	30.350	Oryzias_latipes_hsok
ENSG00000125630	POLR1B	99	82.065	ENSOMEG00000005073	polr1b	99	75.154	Oryzias_melastigma
ENSG00000125630	POLR1B	90	37.079	ENSOMEG00000007867	polr2b	71	37.079	Oryzias_melastigma
ENSG00000125630	POLR1B	100	95.996	ENSOGAG00000007367	POLR1B	97	95.242	Otolemur_garnettii
ENSG00000125630	POLR1B	90	37.079	ENSOGAG00000015999	POLR2B	75	37.079	Otolemur_garnettii
ENSG00000125630	POLR1B	90	37.931	ENSOGAG00000014775	POLR3B	96	30.112	Otolemur_garnettii
ENSG00000125630	POLR1B	99	95.660	ENSOARG00000020904	POLR1B	100	93.351	Ovis_aries
ENSG00000125630	POLR1B	90	36.891	ENSOARG00000005538	POLR2B	75	36.891	Ovis_aries
ENSG00000125630	POLR1B	90	37.931	ENSOARG00000017461	POLR3B	96	30.000	Ovis_aries
ENSG00000125630	POLR1B	90	37.079	ENSPPAG00000040253	POLR2B	82	30.147	Pan_paniscus
ENSG00000125630	POLR1B	100	100.000	ENSPPAG00000002774	POLR1B	100	99.685	Pan_paniscus
ENSG00000125630	POLR1B	90	37.931	ENSPPAG00000035177	POLR3B	96	30.404	Pan_paniscus
ENSG00000125630	POLR1B	99	96.203	ENSPPRG00000005760	POLR1B	99	96.203	Panthera_pardus
ENSG00000125630	POLR1B	90	36.891	ENSPPRG00000001235	POLR2B	82	30.042	Panthera_pardus
ENSG00000125630	POLR1B	90	37.931	ENSPPRG00000012076	POLR3B	96	30.112	Panthera_pardus
ENSG00000125630	POLR1B	90	36.891	ENSPTIG00000019588	POLR2B	85	30.217	Panthera_tigris_altaica
ENSG00000125630	POLR1B	99	96.203	ENSPTIG00000013496	POLR1B	99	96.203	Panthera_tigris_altaica
ENSG00000125630	POLR1B	90	37.931	ENSPTIG00000022085	POLR3B	96	30.112	Panthera_tigris_altaica
ENSG00000125630	POLR1B	100	100.000	ENSPTRG00000012366	POLR1B	100	99.580	Pan_troglodytes
ENSG00000125630	POLR1B	90	37.931	ENSPTRG00000005390	POLR3B	96	30.404	Pan_troglodytes
ENSG00000125630	POLR1B	90	37.079	ENSPTRG00000016089	POLR2B	82	30.147	Pan_troglodytes
ENSG00000125630	POLR1B	90	37.079	ENSPANG00000004759	POLR2B	82	30.147	Papio_anubis
ENSG00000125630	POLR1B	100	99.134	ENSPANG00000023423	POLR1B	100	98.888	Papio_anubis
ENSG00000125630	POLR1B	90	38.123	ENSPANG00000012252	POLR3B	96	30.198	Papio_anubis
ENSG00000125630	POLR1B	91	40.580	ENSPKIG00000000008	polr2b	89	40.580	Paramormyrops_kingsleyae
ENSG00000125630	POLR1B	99	82.428	ENSPKIG00000007536	polr1b	99	75.397	Paramormyrops_kingsleyae
ENSG00000125630	POLR1B	91	38.123	ENSPKIG00000025403	polr3b	99	30.136	Paramormyrops_kingsleyae
ENSG00000125630	POLR1B	97	31.120	ENSPSIG00000015650	POLR3B	96	31.364	Pelodiscus_sinensis
ENSG00000125630	POLR1B	99	86.829	ENSPSIG00000002443	POLR1B	99	84.387	Pelodiscus_sinensis
ENSG00000125630	POLR1B	84	31.801	ENSPMGG00000021804	polr2b	75	32.184	Periophthalmus_magnuspinnatus
ENSG00000125630	POLR1B	99	81.522	ENSPMGG00000021622	polr1b	99	75.309	Periophthalmus_magnuspinnatus
ENSG00000125630	POLR1B	91	38.050	ENSPEMG00000017461	Polr3b	98	30.137	Peromyscus_maniculatus_bairdii
ENSG00000125630	POLR1B	90	37.079	ENSPEMG00000021804	Polr2b	75	37.079	Peromyscus_maniculatus_bairdii
ENSG00000125630	POLR1B	99	94.937	ENSPEMG00000008619	Polr1b	100	91.542	Peromyscus_maniculatus_bairdii
ENSG00000125630	POLR1B	86	30.643	ENSPMAG00000001164	-	93	30.913	Petromyzon_marinus
ENSG00000125630	POLR1B	67	33.482	ENSPMAG00000008197	-	99	38.076	Petromyzon_marinus
ENSG00000125630	POLR1B	67	37.004	ENSPMAG00000007718	-	58	35.055	Petromyzon_marinus
ENSG00000125630	POLR1B	90	37.931	ENSPCIG00000009510	POLR3B	96	30.783	Phascolarctos_cinereus
ENSG00000125630	POLR1B	96	30.147	ENSPCIG00000000898	POLR2B	77	30.147	Phascolarctos_cinereus
ENSG00000125630	POLR1B	99	91.682	ENSPCIG00000029738	POLR1B	96	86.479	Phascolarctos_cinereus
ENSG00000125630	POLR1B	99	82.246	ENSPFOG00000010484	polr1b	99	76.367	Poecilia_formosa
ENSG00000125630	POLR1B	97	30.619	ENSPFOG00000016446	polr3b	96	30.017	Poecilia_formosa
ENSG00000125630	POLR1B	90	37.079	ENSPFOG00000017023	polr2b	75	37.079	Poecilia_formosa
ENSG00000125630	POLR1B	99	82.246	ENSPLAG00000007518	polr1b	99	76.367	Poecilia_latipinna
ENSG00000125630	POLR1B	97	30.619	ENSPLAG00000015107	polr3b	96	30.017	Poecilia_latipinna
ENSG00000125630	POLR1B	90	37.079	ENSPLAG00000023984	polr2b	75	37.079	Poecilia_latipinna
ENSG00000125630	POLR1B	90	37.079	ENSPMEG00000012625	polr2b	75	37.079	Poecilia_mexicana
ENSG00000125630	POLR1B	97	30.619	ENSPMEG00000018524	polr3b	98	30.651	Poecilia_mexicana
ENSG00000125630	POLR1B	99	82.246	ENSPMEG00000006810	polr1b	99	76.455	Poecilia_mexicana
ENSG00000125630	POLR1B	97	30.515	ENSPREG00000017553	polr3b	90	30.183	Poecilia_reticulata
ENSG00000125630	POLR1B	99	82.609	ENSPREG00000002867	polr1b	99	76.367	Poecilia_reticulata
ENSG00000125630	POLR1B	90	37.079	ENSPREG00000011157	polr2b	82	30.252	Poecilia_reticulata
ENSG00000125630	POLR1B	90	37.079	ENSPPYG00000014743	POLR2B	75	37.079	Pongo_abelii
ENSG00000125630	POLR1B	90	37.931	ENSPPYG00000004905	POLR3B	96	30.112	Pongo_abelii
ENSG00000125630	POLR1B	100	99.134	ENSPPYG00000012168	POLR1B	100	98.678	Pongo_abelii
ENSG00000125630	POLR1B	72	49.606	ENSPCAG00000000881	POLR3B	72	49.606	Procavia_capensis
ENSG00000125630	POLR1B	94	94.624	ENSPCAG00000013293	POLR1B	100	81.690	Procavia_capensis
ENSG00000125630	POLR1B	96	30.859	ENSPCOG00000014476	POLR3B	87	30.477	Propithecus_coquereli
ENSG00000125630	POLR1B	100	95.563	ENSPCOG00000015852	POLR1B	100	95.181	Propithecus_coquereli
ENSG00000125630	POLR1B	99	87.255	ENSPVAG00000005727	POLR1B	92	83.451	Pteropus_vampyrus
ENSG00000125630	POLR1B	78	36.957	ENSPVAG00000010951	POLR2B	75	36.957	Pteropus_vampyrus
ENSG00000125630	POLR1B	90	37.931	ENSPVAG00000005861	POLR3B	74	37.931	Pteropus_vampyrus
ENSG00000125630	POLR1B	90	37.079	ENSPNYG00000000002	polr2b	75	37.079	Pundamilia_nyererei
ENSG00000125630	POLR1B	97	30.896	ENSPNYG00000001408	polr3b	96	30.163	Pundamilia_nyererei
ENSG00000125630	POLR1B	99	82.971	ENSPNYG00000004767	polr1b	99	76.631	Pundamilia_nyererei
ENSG00000125630	POLR1B	99	84.058	ENSPNAG00000013503	polr1b	95	77.425	Pygocentrus_nattereri
ENSG00000125630	POLR1B	90	38.095	ENSPNAG00000019044	polr3b	96	30.397	Pygocentrus_nattereri
ENSG00000125630	POLR1B	90	37.523	ENSPNAG00000012064	polr2b	75	37.523	Pygocentrus_nattereri
ENSG00000125630	POLR1B	90	38.050	ENSRNOG00000007432	Polr3b	96	30.285	Rattus_norvegicus
ENSG00000125630	POLR1B	94	94.304	ENSRNOG00000018349	Polr1b	94	94.304	Rattus_norvegicus
ENSG00000125630	POLR1B	90	37.079	ENSRNOG00000024779	Polr2b	75	37.079	Rattus_norvegicus
ENSG00000125630	POLR1B	68	37.079	ENSRBIG00000042838	POLR2B	97	38.067	Rhinopithecus_bieti
ENSG00000125630	POLR1B	99	100.000	ENSRBIG00000019757	POLR1B	100	98.739	Rhinopithecus_bieti
ENSG00000125630	POLR1B	96	30.348	ENSRBIG00000031554	POLR3B	91	30.254	Rhinopithecus_bieti
ENSG00000125630	POLR1B	90	37.079	ENSRROG00000027560	POLR2B	82	30.147	Rhinopithecus_roxellana
ENSG00000125630	POLR1B	90	37.931	ENSRROG00000040685	POLR3B	96	30.755	Rhinopithecus_roxellana
ENSG00000125630	POLR1B	90	37.452	YOR207C	RET1	86	30.637	Saccharomyces_cerevisiae
ENSG00000125630	POLR1B	91	38.067	YOR151C	RPB2	83	38.067	Saccharomyces_cerevisiae
ENSG00000125630	POLR1B	99	44.799	YPR010C	RPA135	97	43.504	Saccharomyces_cerevisiae
ENSG00000125630	POLR1B	67	34.513	ENSSBOG00000023163	POLR2B	53	37.828	Saimiri_boliviensis_boliviensis
ENSG00000125630	POLR1B	90	38.123	ENSSBOG00000033029	POLR3B	96	30.198	Saimiri_boliviensis_boliviensis
ENSG00000125630	POLR1B	100	98.319	ENSSBOG00000024562	POLR1B	100	98.319	Saimiri_boliviensis_boliviensis
ENSG00000125630	POLR1B	90	38.123	ENSSHAG00000012005	POLR3B	96	30.363	Sarcophilus_harrisii
ENSG00000125630	POLR1B	72	81.522	ENSSHAG00000017013	-	100	84.419	Sarcophilus_harrisii
ENSG00000125630	POLR1B	96	30.147	ENSSHAG00000016080	POLR2B	78	30.147	Sarcophilus_harrisii
ENSG00000125630	POLR1B	90	37.899	ENSSFOG00015007437	polr3b	96	30.017	Scleropages_formosus
ENSG00000125630	POLR1B	84	36.330	ENSSFOG00015000924	POLR2B	76	36.330	Scleropages_formosus
ENSG00000125630	POLR1B	99	81.522	ENSSFOG00015004632	polr1b	99	72.823	Scleropages_formosus
ENSG00000125630	POLR1B	90	38.462	ENSSMAG00000006647	polr3b	97	30.446	Scophthalmus_maximus
ENSG00000125630	POLR1B	99	83.333	ENSSMAG00000013682	polr1b	99	75.661	Scophthalmus_maximus
ENSG00000125630	POLR1B	90	37.079	ENSSDUG00000016496	polr2b	85	30.558	Seriola_dumerili
ENSG00000125630	POLR1B	97	30.722	ENSSDUG00000018703	polr3b	96	30.103	Seriola_dumerili
ENSG00000125630	POLR1B	99	83.333	ENSSDUG00000019471	polr1b	99	76.720	Seriola_dumerili
ENSG00000125630	POLR1B	97	30.722	ENSSLDG00000022853	polr3b	98	30.060	Seriola_lalandi_dorsalis
ENSG00000125630	POLR1B	90	37.079	ENSSLDG00000016811	polr2b	75	37.079	Seriola_lalandi_dorsalis
ENSG00000125630	POLR1B	50	67.793	ENSSLDG00000015398	POLR1B	97	67.793	Seriola_lalandi_dorsalis
ENSG00000125630	POLR1B	79	31.481	ENSSARG00000001151	POLR2B	69	31.481	Sorex_araneus
ENSG00000125630	POLR1B	99	85.827	ENSSARG00000008055	-	58	92.308	Sorex_araneus
ENSG00000125630	POLR1B	67	34.821	ENSSARG00000013960	POLR3B	64	37.736	Sorex_araneus
ENSG00000125630	POLR1B	99	86.829	ENSSPUG00000014298	POLR1B	99	82.449	Sphenodon_punctatus
ENSG00000125630	POLR1B	67	34.071	ENSSPUG00000018295	POLR2B	97	37.575	Sphenodon_punctatus
ENSG00000125630	POLR1B	67	34.513	ENSSPAG00000019229	-	97	37.773	Stegastes_partitus
ENSG00000125630	POLR1B	99	82.971	ENSSPAG00000006345	polr1b	99	76.984	Stegastes_partitus
ENSG00000125630	POLR1B	90	37.079	ENSSPAG00000004829	POLR2B	75	37.079	Stegastes_partitus
ENSG00000125630	POLR1B	100	94.697	ENSSSCG00000008098	POLR1B	100	88.370	Sus_scrofa
ENSG00000125630	POLR1B	90	36.891	ENSSSCG00000022955	POLR2B	71	36.891	Sus_scrofa
ENSG00000125630	POLR1B	90	37.931	ENSSSCG00000000169	POLR3B	96	30.881	Sus_scrofa
ENSG00000125630	POLR1B	90	37.828	ENSTGUG00000002929	POLR2B	87	30.000	Taeniopygia_guttata
ENSG00000125630	POLR1B	99	76.585	ENSTGUG00000005237	POLR1B	99	74.300	Taeniopygia_guttata
ENSG00000125630	POLR1B	90	37.833	ENSTGUG00000011035	POLR3B	96	30.829	Taeniopygia_guttata
ENSG00000125630	POLR1B	99	82.609	ENSTRUG00000006581	polr1b	99	76.190	Takifugu_rubripes
ENSG00000125630	POLR1B	97	30.928	ENSTRUG00000008680	polr3b	96	30.189	Takifugu_rubripes
ENSG00000125630	POLR1B	96	30.252	ENSTRUG00000008631	POLR2B	90	30.252	Takifugu_rubripes
ENSG00000125630	POLR1B	99	83.514	ENSTNIG00000002722	polr1b	99	75.704	Tetraodon_nigroviridis
ENSG00000125630	POLR1B	97	31.031	ENSTNIG00000012138	polr3b	97	30.117	Tetraodon_nigroviridis
ENSG00000125630	POLR1B	90	36.891	ENSTNIG00000004894	polr2b	77	36.891	Tetraodon_nigroviridis
ENSG00000125630	POLR1B	67	34.232	ENSTBEG00000014590	POLR2B	59	34.232	Tupaia_belangeri
ENSG00000125630	POLR1B	81	41.497	ENSTBEG00000017278	POLR3B	76	41.497	Tupaia_belangeri
ENSG00000125630	POLR1B	100	90.625	ENSTBEG00000014861	-	61	94.495	Tupaia_belangeri
ENSG00000125630	POLR1B	90	36.617	ENSTTRG00000010839	POLR2B	76	36.617	Tursiops_truncatus
ENSG00000125630	POLR1B	99	95.841	ENSTTRG00000010988	POLR1B	100	93.921	Tursiops_truncatus
ENSG00000125630	POLR1B	82	37.931	ENSTTRG00000010682	POLR3B	84	33.333	Tursiops_truncatus
ENSG00000125630	POLR1B	68	33.383	ENSUAMG00000024267	POLR3B	93	33.383	Ursus_americanus
ENSG00000125630	POLR1B	99	96.098	ENSUAMG00000022527	-	98	94.424	Ursus_americanus
ENSG00000125630	POLR1B	60	34.466	ENSUAMG00000003345	-	89	36.779	Ursus_americanus
ENSG00000125630	POLR1B	90	37.931	ENSUMAG00000017384	POLR3B	96	30.112	Ursus_maritimus
ENSG00000125630	POLR1B	99	96.098	ENSUMAG00000008619	POLR1B	100	94.097	Ursus_maritimus
ENSG00000125630	POLR1B	90	36.891	ENSUMAG00000008247	POLR2B	77	36.891	Ursus_maritimus
ENSG00000125630	POLR1B	84	36.704	ENSVPAG00000000469	POLR2B	70	36.704	Vicugna_pacos
ENSG00000125630	POLR1B	83	39.456	ENSVPAG00000010478	POLR3B	70	39.456	Vicugna_pacos
ENSG00000125630	POLR1B	99	94.118	ENSVPAG00000011111	POLR1B	93	93.307	Vicugna_pacos
ENSG00000125630	POLR1B	90	37.931	ENSVVUG00000023101	POLR3B	95	33.333	Vulpes_vulpes
ENSG00000125630	POLR1B	99	96.203	ENSVVUG00000028670	POLR1B	100	93.744	Vulpes_vulpes
ENSG00000125630	POLR1B	90	36.891	ENSVVUG00000005979	POLR2B	75	36.891	Vulpes_vulpes
ENSG00000125630	POLR1B	99	84.865	ENSXETG00000013749	polr1b	99	77.425	Xenopus_tropicalis
ENSG00000125630	POLR1B	97	30.510	ENSXETG00000005721	polr3b	96	30.510	Xenopus_tropicalis
ENSG00000125630	POLR1B	84	31.978	ENSXETG00000005329	polr2b	69	31.978	Xenopus_tropicalis
ENSG00000125630	POLR1B	97	30.412	ENSXCOG00000020478	polr3b	94	30.407	Xiphophorus_couchianus
ENSG00000125630	POLR1B	99	82.609	ENSXCOG00000006080	polr1b	99	76.190	Xiphophorus_couchianus
ENSG00000125630	POLR1B	97	30.412	ENSXMAG00000001568	polr3b	90	30.092	Xiphophorus_maculatus
ENSG00000125630	POLR1B	99	82.609	ENSXMAG00000007723	polr1b	99	76.102	Xiphophorus_maculatus
ENSG00000125630	POLR1B	90	37.079	ENSXMAG00000015282	polr2b	75	37.079	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	21873635.	IBA	Function
GO:0005515	protein binding	16514417.19214185.20208542.26496610.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0007566	embryo implantation	-	IEA	Process
GO:0009303	rRNA transcription	-	IEA	Process
GO:0017126	nucleologenesis	-	IEA	Process
GO:0032549	ribonucleoside binding	-	IEA	Function
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process
GO:0046872	metal ion binding	-	IEA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr2	112572709	Missense_Mutation	novel	A741V	0.25
BLCA	chr2	112575171	Missense_Mutation	novel	F950L	0.1
BLCA	chr2	112572653	Silent	rs770267443	V722V	0.18
BLCA	chr2	112542463	5'UTR	novel		0.55
BLCA	chr2	112575763	3'UTR	novel		0.27
BLCA	chr2	112552666	Silent	novel	L336L	0.12
BLCA	chr2	112568024	Frame_Shift_Ins	novel	*G602Afs17**	0.26
BLCA	chr2	112568025	Missense_Mutation	novel	G602E	0.26
BLCA	chr2	112575166	Frame_Shift_Ins	novel	*P949Lfs17**	0.23
BLCA	chr2	112575112	Missense_Mutation	novel	E931Q	0.27
BRCA	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.2	RNA_pol_Rpa2_4
BRCA	chr2	112575089	Missense_Mutation	NA	R923H	0.16
BRCA	chr2	112559462	Silent	NA	V500V	0.33
BRCA	chr2	112564364	Splice_Site	NA	X538_splice	0.28
BRCA	chr2	112575005	Missense_Mutation	NA	R895I	0.43
BRCA	chr2	112542384	5'UTR	novel		0.12
BRCA	chr2	112568038	Silent	NA	L606L	0.2
BRCA	chr2	112559492	Silent	NA	L510L	0.19
CESC	chr2	112558015	Missense_Mutation	rs755620310	M422V	0.26
CESC	chr2	112575535	Frame_Shift_Del	novel	*K1072Vfs30**	0.09
CESC	chr2	112575536	Frame_Shift_Ins	novel	*K1072Nfs33**	0.09
CESC	chr2	112550995	Missense_Mutation	novel	A252V	0.13	RNA_pol_Rpa2_4
CESC	chr2	112551900	Silent	novel	T296T	0.39
CESC	chr2	112552763	Silent	novel	L369L	0.41
CESC	chr2	112542486	5'UTR	novel		0.18
CESC	chr2	112575685	Missense_Mutation	NA	E1122K	0.29
CESC	chr2	112575552	Silent	novel	L1077L	0.26
CESC	chr2	112542656	Silent	NA	L54L	0.06
CESC	chr2	112547498	Silent	novel	V141V	0.1
CESC	chr2	112558016	Missense_Mutation	novel	M422K	0.15
CESC	chr2	112549393	Missense_Mutation	NA	Q207E	0.45	RNA_pol_Rpa2_4
COAD	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.14	RNA_pol_Rpa2_4
COAD	chr2	112574971	Missense_Mutation	NA	A884T	0.23
COAD	chr2	112568848	Missense_Mutation	NA	I674V	0.37
COAD	chr2	112573790	Missense_Mutation	rs553658068	G834R	0.46
COAD	chr2	112575015	Silent	rs149946383	P898P	0.39
COAD	chr2	112574895	Silent	NA	D858D	0.36
COAD	chr2	112568055	Frame_Shift_Del	novel	*F613Lfs14**	0.08
COAD	chr2	112550989	Missense_Mutation	novel	G250V	0.16	RNA_pol_Rpa2_4
COAD	chr2	112551983	Missense_Mutation	rs189205115	A324V	0.16
COAD	chr2	112559543	Silent	rs772777628	T527T	0.19
COAD	chr2	112572753	Missense_Mutation	novel	A756T	0.29
COAD	chr2	112575263	Missense_Mutation	novel	S981N	0.35
COAD	chr2	112547048	Missense_Mutation	rs376500705	R72C	0.15
COAD	chr2	112547523	Missense_Mutation	NA	N150Y	0.08	RNA_pol_Rpa2_4
COAD	chr2	112559474	Silent	rs756079439	D504D	0.11
COAD	chr2	112551801	Silent	novel	Q263Q	0.05
COAD	chr2	112551802	Frame_Shift_Ins	novel	*I264Sfs26**	0.05	RNA_pol_Rpa2_4
COAD	chr2	112551942	Frame_Shift_Del	novel	*K311Nfs26**	0.28
COAD	chr2	112575428	Missense_Mutation	novel	R1036H	0.08
COAD	chr2	112568016	Missense_Mutation	novel	P599L	0.05
ESCA	chr2	112575358	Silent	novel	R1013R	0.15
ESCA	chr2	112573561	Splice_Site	novel	X758_splice	0.21
ESCA	chr2	112549391	Missense_Mutation	novel	T206N	0.25	RNA_pol_Rpa2_4
GBM	chr2	112575874	3'UTR	novel		0.54
GBM	chr2	112547129	Missense_Mutation	novel	Y99H	0.37
GBM	chr2	112575199	Nonsense_Mutation	novel	E960*	0.12
GBM	chr2	112558039	Missense_Mutation	NA	F430L	0.21
HNSC	chr2	112559306	Silent	rs758154850	L448L	0.22
HNSC	chr2	112574968	Frame_Shift_Del	novel	*F883Lfs11**	0.25
HNSC	chr2	112564475	Silent	rs373513321	I574I	0.15
HNSC	chr2	112573748	Nonsense_Mutation	NA	Q820*	0.16
HNSC	chr2	112564452	Missense_Mutation	novel	D567H	0.16
KIRC	chr2	112552793	Nonsense_Mutation	novel	Q379*	0.14
KIRC	chr2	112550938	Missense_Mutation	NA	T233N	0.2	RNA_pol_Rpa2_4
KIRC	chr2	112559398	Missense_Mutation	NA	A479V	0.2
KIRP	chr2	112572703	In_Frame_Del	novel	N740_A741del	0.19
KIRP	chr2	112550975	Frame_Shift_Del	novel	*L247Gfs5**	0.25	RNA_pol_Rpa2_4
LAML	chr2	112547100	Missense_Mutation	NA	K89R	0.1
LAML	chr2	112564448	Missense_Mutation	novel	W565C	0.03
LGG	chr2	112564430	Silent	rs189967507	D559D	0.35
LGG	chr2	112547520	Missense_Mutation	rs754005341	R149C	0.11	RNA_pol_Rpa2_4
LUAD	chr2	112551774	Splice_Site	NA	X255_splice	0.41
LUAD	chr2	112572733	Missense_Mutation	novel	T749I	0.39
LUAD	chr2	112573790	Missense_Mutation	NA	G834W	0.3
LUAD	chr2	112542656	Silent	NA	L54L	0.51
LUAD	chr2	112542623	Silent	novel	V43V	0.34
LUAD	chr2	112559364	Missense_Mutation	NA	H468Y	0.29
LUAD	chr2	112547477	Frame_Shift_Ins	novel	*Y136Lfs15**	0.06	RNA_pol_Rpa2_4
LUAD	chr2	112573653	Missense_Mutation	novel	G788A	0.06
LUAD	chr2	112547466	Frame_Shift_Del	novel	*K131Sfs11**	0.22	RNA_pol_Rpa2_4
LUAD	chr2	112542416	5'UTR	novel		0.15
LUAD	chr2	112551894	Silent	novel	C294C	0.49
LUAD	chr2	112559520	Missense_Mutation	NA	V520F	0.51
LUAD	chr2	112547506	Missense_Mutation	NA	K144M	0.15	RNA_pol_Rpa2_4
LUAD	chr2	112547112	Missense_Mutation	NA	C93S	0.23
LUSC	chr2	112551823	Missense_Mutation	novel	G271R	0.22	RNA_pol_Rpa2_4
LUSC	chr2	112559462	Silent	novel	V500V	0.33
LUSC	chr2	112573655	Missense_Mutation	novel	D789N	0.1
LUSC	chr2	112547096	Missense_Mutation	NA	P88S	0.41
LUSC	chr2	112550961	Nonsense_Mutation	rs762525524	R241*	0.19	RNA_pol_Rpa2_4
LUSC	chr2	112542601	Missense_Mutation	novel	Q36L	0.22
LUSC	chr2	112550982	Missense_Mutation	novel	P248S	0.12	RNA_pol_Rpa2_4
LUSC	chr2	112568045	Nonsense_Mutation	novel	G609*	0.14
LUSC	chr2	112559455	Missense_Mutation	novel	C498S	0.24
LUSC	chr2	112552787	Missense_Mutation	novel	P377A	0.29
LUSC	chr2	112542478	5'UTR	novel		0.31
OV	chr2	112547521	Missense_Mutation	novel	R149P	0.09	RNA_pol_Rpa2_4
OV	chr2	112576061	3'UTR	novel		0.4
OV	chr2	112542463	5'UTR	novel		0.07
OV	chr2	112557999	Missense_Mutation	novel	L416F	0.12
OV	chr2	112542442	5'UTR	novel		0.44
OV	chr2	112576061	3'UTR	novel		0.63
OV	chr2	112547053	Missense_Mutation	novel	I73M	0.55
PAAD	chr2	112551964	Missense_Mutation	rs748521170	Y318H	0.25
PAAD	chr2	112558070	Missense_Mutation	rs369255960	R440H	0.11
PAAD	chr2	112575619	Silent	novel	L1100L	0.28
PAAD	chr2	112564467	Missense_Mutation	NA	P572S	0.16
PCPG	chr2	112549326	Missense_Mutation	novel	M184I	0.1	RNA_pol_Rpa2_4
PRAD	chr2	112542667	Missense_Mutation	novel	V58E	0.36
PRAD	chr2	112575328	Missense_Mutation	NA	R1003G	0.31
PRAD	chr2	112575596	Missense_Mutation	rs778970340	R1092H	0.23
READ	chr2	112575643	Missense_Mutation	NA	D1108N	0.35
READ	chr2	112575506	Missense_Mutation	NA	S1062L	0.41
READ	chr2	112551839	Missense_Mutation	NA	S276Y	0.27	RNA_pol_Rpa2_4
READ	chr2	112575186	Missense_Mutation	novel	E955D	0.36
READ	chr2	112542562	Missense_Mutation	NA	S23F	0.1
SARC	chr2	112575642	Silent	rs770178332	I1107I	0.51
SKCM	chr2	112542351	5'UTR	novel		0.75
SKCM	chr2	112551001	Missense_Mutation	NA	K254R	0.28	RNA_pol_Rpa2_4
SKCM	chr2	112575395	Missense_Mutation	novel	P1025R	0.45
SKCM	chr2	112575396	Silent	rs200088024	P1025P	0.44
SKCM	chr2	112542427	5'UTR	novel		0.57
SKCM	chr2	112559469	Missense_Mutation	novel	P503S	0.06
SKCM	chr2	112552671	Missense_Mutation	NA	S338F	0.14
SKCM	chr2	112567984	Silent	NA	R588R	0.37
SKCM	chr2	112564390	Missense_Mutation	NA	P546L	0.23
SKCM	chr2	112551990	Silent	novel	F326F	0.31
SKCM	chr2	112568854	Missense_Mutation	novel	F676V	0.28
SKCM	chr2	112559370	Missense_Mutation	rs777944795	R470C	0.21
SKCM	chr2	112564488	Missense_Mutation	rs756577897	R579C	0.12
SKCM	chr2	112575574	Missense_Mutation	NA	P1085A	0.49
SKCM	chr2	112564390	Missense_Mutation	NA	P546L	0.12
SKCM	chr2	112557935	Missense_Mutation	NA	S395F	0.45
SKCM	chr2	112547096	Missense_Mutation	NA	P88S	0.44
SKCM	chr2	112568760	Silent	rs373607748	V644V	0.1
SKCM	chr2	112559411	Silent	novel	T483T	0.25
SKCM	chr2	112568743	Splice_Region	novel		0.42
SKCM	chr2	112547487	Missense_Mutation	novel	P138S	0.43	RNA_pol_Rpa2_4
SKCM	chr2	112551990	Silent	novel	F326F	0.38
SKCM	chr2	112573633	Silent	NA	L781L	0.41
SKCM	chr2	112542427	5'UTR	novel		0.33
SKCM	chr2	112573637	Missense_Mutation	novel	E783K	0.35
SKCM	chr2	112575386	Missense_Mutation	novel	T1022I	0.42
STAD	chr2	112575103	Missense_Mutation	NA	M928V	0.09
STAD	chr2	112558080	Splice_Region	NA	T443T	0.3
STAD	chr2	112552710	Missense_Mutation	NA	R351Q	0.37
STAD	chr2	112572619	Missense_Mutation	NA	L711R	0.31
STAD	chr2	112575643	Missense_Mutation	NA	D1108N	0.29
STAD	chr2	112575165	Silent	NA	T948T	0.12
STAD	chr2	112549324	Missense_Mutation	NA	M184V	0.42	RNA_pol_Rpa2_4
STAD	chr2	112564430	Silent	rs189967507	D559D	0.15
STAD	chr2	112573657	Frame_Shift_Ins	novel	*S790Kfs2**	0.25
STAD	chr2	112550900	Silent	rs144737583	S220S	0.19
STAD	chr2	112575290	Missense_Mutation	NA	A990V	0.27
STAD	chr2	112547047	Silent	NA	E71E	0.19
STAD	chr2	112575935	3'UTR	novel		0.5
STAD	chr2	112573690	Silent	NA	D800D	0.28
THCA	chr2	112575373	Nonsense_Mutation	NA	R1018*	0.32
THCA	chr2	112575082	In_Frame_Del	novel	P921del	0.31
THCA	chr2	112575385	Missense_Mutation	novel	T1022A	0.06
THCA	chr2	112551992	Frame_Shift_Ins	novel	*F328Rfs4**	0.1
UCEC	chr2	112558042	Missense_Mutation	NA	E431K	0.41
UCEC	chr2	112572607	Missense_Mutation	rs768820442	S707L	0.4
UCEC	chr2	112550967	Nonsense_Mutation	NA	E243*	0.31	RNA_pol_Rpa2_4
UCEC	chr2	112575942	3'UTR	novel		0.63
UCEC	chr2	112575515	Missense_Mutation	NA	S1065L	0.29
UCEC	chr2	112568750	Missense_Mutation	novel	F641S	0.15
UCEC	chr2	112575780	3'UTR	novel		0.14
UCEC	chr2	112575240	Missense_Mutation	NA	F973L	0.46
UCEC	chr2	112575596	Missense_Mutation	rs778970340	R1092H	0.42
UCEC	chr2	112547027	Missense_Mutation	NA	E65K	0.24
UCEC	chr2	112568009	Missense_Mutation	novel	L597I	0.05
UCEC	chr2	112574925	Silent	NA	C868C	0.3
UCEC	chr2	112575596	Missense_Mutation	rs778970340	R1092H	0.32
UCEC	chr2	112552707	Missense_Mutation	rs372536940	T350M	0.2
UCEC	chr2	112564476	Missense_Mutation	rs564653507	A575T	0.44
UCEC	chr2	112568054	Frame_Shift_Ins	novel	*T614Yfs5**	0.38
UCEC	chr2	112542591	Missense_Mutation	novel	A33S	0.54
UCEC	chr2	112550967	Nonsense_Mutation	NA	E243*	0.4	RNA_pol_Rpa2_4
UCEC	chr2	112575642	Silent	rs770178332	I1107I	0.42
UCEC	chr2	112575595	Missense_Mutation	rs200995508	R1092C	0.15
UCEC	chr2	112552802	Missense_Mutation	novel	L382F	0.3
UCEC	chr2	112573596	Missense_Mutation	novel	A769V	0.54
UCEC	chr2	112564430	Silent	rs189967507	D559D	0.31
UCEC	chr2	112572608	Silent	rs376407464	S707S	0.41
UCEC	chr2	112573717	Silent	rs747625945	D809D	0.45
UCEC	chr2	112575559	Silent	rs767048101	L1080L	0.09
UCEC	chr2	112559456	Silent	rs199656923	C498C	0.47
UCEC	chr2	112564489	Missense_Mutation	rs148143581	R579H	0.46
UCEC	chr2	112564488	Missense_Mutation	rs756577897	R579C	0.52
UCEC	chr2	112559509	Missense_Mutation	novel	A516V	0.39
UCEC	chr2	112575373	Nonsense_Mutation	NA	R1018*	0.5
UCEC	chr2	112573696	Silent	rs770053789	R802R	0.5
UCEC	chr2	112547109	Missense_Mutation	NA	I92T	0.34
UCEC	chr2	112552702	Silent	rs760932513	L348L	0.25
UCEC	chr2	112572670	Missense_Mutation	novel	D728A	0.42
UCEC	chr2	112559466	Missense_Mutation	novel	T502A	0.39
UCEC	chr2	112547509	Missense_Mutation	novel	L145R	0.24	RNA_pol_Rpa2_4
UCEC	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.16	RNA_pol_Rpa2_4
UCEC	chr2	112575595	Missense_Mutation	rs200995508	R1092C	0.43
UCEC	chr2	112559505	Missense_Mutation	novel	T515A	0.34
UCEC	chr2	112575123	Silent	rs773418660	A934A	0.42
UCEC	chr2	112572749	Missense_Mutation	novel	E754D	0.45
UCEC	chr2	112575446	Missense_Mutation	novel	R1042Q	0.37
UCEC	chr2	112575803	3'UTR	novel		0.36
UCEC	chr2	112575589	Missense_Mutation	novel	A1090T	0.22
UCEC	chr2	112573638	Frame_Shift_Del	novel	*I785Lfs23**	0.11
UCEC	chr2	112568765	Missense_Mutation	NA	I646S	0.3
UCEC	chr2	112568854	Missense_Mutation	novel	F676L	0.09
UCEC	chr2	112559352	Missense_Mutation	NA	R464C	0.32
UCEC	chr2	112575643	Missense_Mutation	NA	D1108N	0.25
UCEC	chr2	112547445	Missense_Mutation	novel	G124R	0.23	RNA_pol_Rpa2_4
UCEC	chr2	112575769	3'UTR	novel		0.43
UCEC	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.4	RNA_pol_Rpa2_4
UCEC	chr2	112551876	Silent	NA	I288I	0.47
UCEC	chr2	112558010	Missense_Mutation	NA	F420C	0.45
UCEC	chr2	112564483	Missense_Mutation	NA	S577Y	0.43
UCEC	chr2	112568786	Missense_Mutation	NA	A653D	0.27
UCEC	chr2	112575935	3'UTR	novel		0.75
UCEC	chr2	112551003	Splice_Site	novel	X254_splice	0.17
UCEC	chr2	112564476	Missense_Mutation	rs564653507	A575T	0.42
UCEC	chr2	112568085	Missense_Mutation	novel	P622H	0.4
UCEC	chr2	112573790	Missense_Mutation	rs553658068	G834R	0.41
UCEC	chr2	112574958	Silent	rs377301934	I879I	0.23
UCEC	chr2	112575841	3'UTR	novel		0.21
UCEC	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.42	RNA_pol_Rpa2_4
UCEC	chr2	112542535	Missense_Mutation	novel	P14H	0.36
UCEC	chr2	112551791	Missense_Mutation	NA	S260Y	0.46	RNA_pol_Rpa2_4
UCEC	chr2	112547521	Frame_Shift_Del	novel	*R149Lfs23**	0.53	RNA_pol_Rpa2_4
UCEC	chr2	112575601	Nonsense_Mutation	novel	R1094*	0.38
UCS	chr2	112550962	Missense_Mutation	rs766030588	R241Q	0.2	RNA_pol_Rpa2_4
UVM	chr2	112575029	Missense_Mutation	novel	P903L	0.39

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1778	0.15279
CESC	DEL	0.078	0.00029523
CHOL	DEL	0	3.3987e-23
DLBC	DEL	0.0625	0.011841
ESCA	DEL	0.0435	0.0012162
KIRC	DEL	0.0227	2.3538e-09
KIRP	DEL	0.0139	1.462e-09
LIHC	DEL	0.0946	1.6679e-20
LUAD	DEL	0.0233	0.0024765
LUSC	DEL	0.0319	2.5882e-07
MESO	DEL	0.046	2.434e-07
PAAD	DEL	0.038	0.2014
READ	DEL	0.0364	2.1758e-10
TGCT	DEL	0.0267	0.00046313

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.021	Kaplan-Meier Survival Analysis
ACC	0.018	Kaplan-Meier Survival Analysis
PRAD	0.044	Kaplan-Meier Survival Analysis
KIRP	0.00046	Kaplan-Meier Survival Analysis
PCPG	0.043	Kaplan-Meier Survival Analysis
CESC	0.0078	Kaplan-Meier Survival Analysis
READ	0.041	Kaplan-Meier Survival Analysis
KICH	0.0005	Kaplan-Meier Survival Analysis
UCEC	0.0001	Kaplan-Meier Survival Analysis
LIHC	0.022	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742