EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125652 (Gene tree)
Gene ID: 84266
Gene Symbol: ALKBH7
Alias: MGC10974|SPATA11
Full Name: alkB homolog 7
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,819 bases
Position: chr19:6,372,433-6,375,251
Accession: 21306
RBP type: canonical RBP
Summary: ALKBH7 (AlkB Homolog 7) is a Protein Coding gene. Among its related pathways are DNA Damage and Apoptosis and Autophagy. Gene Ontology (GO) annotations related to this gene include dioxygenase activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000245812	2OG-FeII_Oxy_2	PF13532.6	2.4e-11	1	1
ENSP00000470562	2OG-FeII_Oxy_2	PF13532.6	5e-11	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25122757	The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism.	J Biol Chem	2014 Oct 3	Wang G	doi: 10.1074/jbc.M114.590505

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000599849	ALKBH7-203	556	-	ENSP00000470562	160 (aa)	-	M0QZI0
ENST00000596657	ALKBH7-202	603	-	ENSP00000470542	79 (aa)	-	M0QZH2
ENST00000245812	ALKBH7-201	1332	XM_017027355	ENSP00000245812	221 (aa)	XP_016882844	Q9BT30

Gene Model

Click here to download ENSG00000125652's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125652	Child Development Disorders, Pervasive	4.7399000E-005	-
ENSG00000125652	Child Development Disorders, Pervasive	4.1626200E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125652's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125652	ALKBH7	91	63.014	ENSAPOG00000007277	alkbh7	100	63.014	Acanthochromis_polyacanthus
ENSG00000125652	ALKBH7	100	97.468	ENSAMEG00000006925	ALKBH7	100	93.213	Ailuropoda_melanoleuca
ENSG00000125652	ALKBH7	87	70.504	ENSACAG00000015548	ALKBH7	95	66.154	Anolis_carolinensis
ENSG00000125652	ALKBH7	100	97.468	ENSANAG00000035316	ALKBH7	100	96.380	Aotus_nancymaae
ENSG00000125652	ALKBH7	100	97.468	ENSBTAG00000025540	ALKBH7	100	92.760	Bos_taurus
ENSG00000125652	ALKBH7	88	44.681	WBGene00012920	Y46G5A.35	79	43.333	Caenorhabditis_elegans
ENSG00000125652	ALKBH7	100	97.468	ENSCJAG00000016691	ALKBH7	100	96.855	Callithrix_jacchus
ENSG00000125652	ALKBH7	100	94.937	ENSCAFG00000018693	ALKBH7	100	93.665	Canis_familiaris
ENSG00000125652	ALKBH7	100	94.937	ENSCAFG00020019096	ALKBH7	100	93.665	Canis_lupus_dingo
ENSG00000125652	ALKBH7	100	98.734	ENSCHIG00000024761	ALKBH7	100	92.308	Capra_hircus
ENSG00000125652	ALKBH7	100	93.671	ENSTSYG00000026277	ALKBH7	99	90.566	Carlito_syrichta
ENSG00000125652	ALKBH7	100	87.342	ENSCAPG00000010286	ALKBH7	100	88.889	Cavia_aperea
ENSG00000125652	ALKBH7	100	87.342	ENSCPOG00000013958	ALKBH7	100	85.068	Cavia_porcellus
ENSG00000125652	ALKBH7	100	92.405	ENSCCAG00000031744	-	83	93.277	Cebus_capucinus
ENSG00000125652	ALKBH7	100	97.468	ENSCCAG00000025999	ALKBH7	100	96.833	Cebus_capucinus
ENSG00000125652	ALKBH7	100	97.468	ENSCATG00000030199	ALKBH7	100	96.875	Cercocebus_atys
ENSG00000125652	ALKBH7	100	87.783	ENSCLAG00000017244	ALKBH7	100	87.783	Chinchilla_lanigera
ENSG00000125652	ALKBH7	100	98.734	ENSCSAG00000009674	ALKBH7	100	98.643	Chlorocebus_sabaeus
ENSG00000125652	ALKBH7	87	71.223	ENSCPBG00000005256	ALKBH7	83	71.223	Chrysemys_picta_bellii
ENSG00000125652	ALKBH7	93	44.295	ENSCING00000003788	-	72	43.017	Ciona_intestinalis
ENSG00000125652	ALKBH7	94	50.980	ENSCSAVG00000004377	-	78	47.368	Ciona_savignyi
ENSG00000125652	ALKBH7	100	98.750	ENSCANG00000032503	ALKBH7	100	98.750	Colobus_angolensis_palliatus
ENSG00000125652	ALKBH7	100	91.139	ENSCGRG00001019380	Alkbh7	100	85.520	Cricetulus_griseus_chok1gshd
ENSG00000125652	ALKBH7	100	91.139	ENSCGRG00000005364	Alkbh7	99	87.421	Cricetulus_griseus_crigri
ENSG00000125652	ALKBH7	88	64.286	ENSCSEG00000013396	alkbh7	81	60.106	Cynoglossus_semilaevis
ENSG00000125652	ALKBH7	100	87.330	ENSDNOG00000005049	ALKBH7	100	87.330	Dasypus_novemcinctus
ENSG00000125652	ALKBH7	100	89.873	ENSDORG00000002441	Alkbh7	100	88.688	Dipodomys_ordii
ENSG00000125652	ALKBH7	100	83.258	ENSETEG00000019330	ALKBH7	100	83.258	Echinops_telfairi
ENSG00000125652	ALKBH7	87	53.957	ENSEBUG00000005766	alkbh7	76	52.663	Eptatretus_burgeri
ENSG00000125652	ALKBH7	100	96.203	ENSECAG00000023627	ALKBH7	100	94.118	Equus_caballus
ENSG00000125652	ALKBH7	100	96.203	ENSFCAG00000012510	ALKBH7	100	93.213	Felis_catus
ENSG00000125652	ALKBH7	100	86.425	ENSFDAG00000014965	ALKBH7	100	86.425	Fukomys_damarensis
ENSG00000125652	ALKBH7	83	69.697	ENSGAGG00000023239	ALKBH7	91	69.697	Gopherus_agassizii
ENSG00000125652	ALKBH7	100	100.000	ENSGGOG00000027915	ALKBH7	100	100.000	Gorilla_gorilla
ENSG00000125652	ALKBH7	100	86.076	ENSHGLG00000018436	ALKBH7	100	84.163	Heterocephalus_glaber_female
ENSG00000125652	ALKBH7	100	86.076	ENSHGLG00100000746	ALKBH7	100	87.912	Heterocephalus_glaber_male
ENSG00000125652	ALKBH7	93	90.732	ENSSTOG00000002368	ALKBH7	100	88.688	Ictidomys_tridecemlineatus
ENSG00000125652	ALKBH7	100	91.139	ENSJJAG00000023908	Alkbh7	99	85.377	Jaculus_jaculus
ENSG00000125652	ALKBH7	86	65.942	ENSKMAG00000001132	alkbh7	86	58.974	Kryptolebias_marmoratus
ENSG00000125652	ALKBH7	87	65.468	ENSLACG00000008513	ALKBH7	84	60.309	Latimeria_chalumnae
ENSG00000125652	ALKBH7	99	87.273	ENSLAFG00000003852	ALKBH7	99	87.273	Loxodonta_africana
ENSG00000125652	ALKBH7	100	98.750	ENSMFAG00000045978	ALKBH7	100	98.750	Macaca_fascicularis
ENSG00000125652	ALKBH7	100	98.734	ENSMMUG00000000054	ALKBH7	100	97.500	Macaca_mulatta
ENSG00000125652	ALKBH7	100	98.750	ENSMNEG00000029223	ALKBH7	100	98.750	Macaca_nemestrina
ENSG00000125652	ALKBH7	100	98.734	ENSMLEG00000039193	ALKBH7	100	97.500	Mandrillus_leucophaeus
ENSG00000125652	ALKBH7	100	89.873	ENSMAUG00000000800	Alkbh7	100	85.520	Mesocricetus_auratus
ENSG00000125652	ALKBH7	100	96.203	ENSMICG00000006288	ALKBH7	100	92.760	Microcebus_murinus
ENSG00000125652	ALKBH7	99	87.179	ENSMOCG00000004923	Alkbh7	99	82.727	Microtus_ochrogaster
ENSG00000125652	ALKBH7	100	88.608	MGP_CAROLIEiJ_G0021797	Alkbh7	100	82.805	Mus_caroli
ENSG00000125652	ALKBH7	100	88.608	ENSMUSG00000002661	Alkbh7	100	81.900	Mus_musculus
ENSG00000125652	ALKBH7	100	84.810	MGP_PahariEiJ_G0020786	Alkbh7	100	81.448	Mus_pahari
ENSG00000125652	ALKBH7	100	88.608	MGP_SPRETEiJ_G0022708	Alkbh7	100	81.448	Mus_spretus
ENSG00000125652	ALKBH7	100	88.608	ENSMLUG00000015076	-	100	88.235	Myotis_lucifugus
ENSG00000125652	ALKBH7	99	84.545	ENSNGAG00000018037	Alkbh7	100	84.545	Nannospalax_galili
ENSG00000125652	ALKBH7	84	89.394	ENSMEUG00000006486	ALKBH7	95	83.571	Notamacropus_eugenii
ENSG00000125652	ALKBH7	100	88.608	ENSODEG00000015141	ALKBH7	100	85.520	Octodon_degus
ENSG00000125652	ALKBH7	100	87.783	ENSOCUG00000006905	ALKBH7	100	87.783	Oryctolagus_cuniculus
ENSG00000125652	ALKBH7	87	63.309	ENSORLG00000018765	alkbh7	87	56.585	Oryzias_latipes
ENSG00000125652	ALKBH7	96	60.784	ENSORLG00020014461	alkbh7	98	60.784	Oryzias_latipes_hni
ENSG00000125652	ALKBH7	87	64.029	ENSORLG00015004045	alkbh7	87	57.073	Oryzias_latipes_hsok
ENSG00000125652	ALKBH7	100	89.873	ENSOGAG00000030625	ALKBH7	100	88.235	Otolemur_garnettii
ENSG00000125652	ALKBH7	100	86.076	ENSOARG00000006195	ALKBH7	90	90.686	Ovis_aries
ENSG00000125652	ALKBH7	100	100.000	ENSPPAG00000028564	ALKBH7	100	100.000	Pan_paniscus
ENSG00000125652	ALKBH7	100	94.937	ENSPPRG00000007447	ALKBH7	100	93.213	Panthera_pardus
ENSG00000125652	ALKBH7	100	100.000	ENSPTRG00000010360	ALKBH7	100	100.000	Pan_troglodytes
ENSG00000125652	ALKBH7	100	98.190	ENSPANG00000035776	ALKBH7	100	98.190	Papio_anubis
ENSG00000125652	ALKBH7	86	68.841	ENSPSIG00000007204	ALKBH7	100	68.841	Pelodiscus_sinensis
ENSG00000125652	ALKBH7	91	61.379	ENSPMGG00000022473	alkbh7	99	61.379	Periophthalmus_magnuspinnatus
ENSG00000125652	ALKBH7	100	86.076	ENSPEMG00000016536	Alkbh7	100	85.068	Peromyscus_maniculatus_bairdii
ENSG00000125652	ALKBH7	89	65.035	ENSPREG00000000807	alkbh7	90	65.035	Poecilia_reticulata
ENSG00000125652	ALKBH7	100	98.734	ENSPPYG00000009450	ALKBH7	100	89.140	Pongo_abelii
ENSG00000125652	ALKBH7	100	82.353	ENSPCAG00000009325	ALKBH7	100	82.353	Procavia_capensis
ENSG00000125652	ALKBH7	100	97.468	ENSPCOG00000028026	ALKBH7	100	93.665	Propithecus_coquereli
ENSG00000125652	ALKBH7	99	92.727	ENSPVAG00000007246	ALKBH7	99	92.727	Pteropus_vampyrus
ENSG00000125652	ALKBH7	100	87.342	ENSRNOG00000047089	Alkbh7	100	82.353	Rattus_norvegicus
ENSG00000125652	ALKBH7	100	98.125	ENSRBIG00000042737	ALKBH7	100	98.125	Rhinopithecus_bieti
ENSG00000125652	ALKBH7	100	98.750	ENSRROG00000043210	ALKBH7	100	98.750	Rhinopithecus_roxellana
ENSG00000125652	ALKBH7	100	98.734	ENSSBOG00000024563	ALKBH7	100	97.285	Saimiri_boliviensis_boliviensis
ENSG00000125652	ALKBH7	100	89.873	ENSSARG00000011291	-	94	91.220	Sorex_araneus
ENSG00000125652	ALKBH7	87	85.612	ENSSARG00000001361	-	99	84.946	Sorex_araneus
ENSG00000125652	ALKBH7	86	73.188	ENSSPUG00000016435	ALKBH7	93	71.765	Sphenodon_punctatus
ENSG00000125652	ALKBH7	100	94.937	ENSSSCG00000024254	ALKBH7	100	86.765	Sus_scrofa
ENSG00000125652	ALKBH7	96	84.314	ENSTBEG00000005798	ALKBH7	100	84.314	Tupaia_belangeri
ENSG00000125652	ALKBH7	100	94.937	ENSTTRG00000010344	ALKBH7	100	91.403	Tursiops_truncatus
ENSG00000125652	ALKBH7	100	97.468	ENSUAMG00000026459	ALKBH7	100	93.213	Ursus_americanus
ENSG00000125652	ALKBH7	92	94.558	ENSUMAG00000011121	ALKBH7	95	92.715	Ursus_maritimus
ENSG00000125652	ALKBH7	100	96.203	ENSVVUG00000026894	ALKBH7	100	94.118	Vulpes_vulpes
ENSG00000125652	ALKBH7	88	60.714	ENSXETG00000005578	alkbh7	96	55.556	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005759	mitochondrial matrix	23666923.	IDA	Component
GO:0006631	fatty acid metabolic process	-	ISS	Process
GO:0006974	cellular response to DNA damage stimulus	23666923.	IDA	Process
GO:0010883	regulation of lipid storage	-	ISS	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0051213	dioxygenase activity	-	IEA	Function
GO:0055114	oxidation-reduction process	-	IEA	Process
GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	23666923.	IMP	Process