EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125743 (Gene tree)
Gene ID: 6633
Gene Symbol: SNRPD2
Alias: Sm-D2|SNRPD1
Full Name: small nuclear ribonucleoprotein D2 polypeptide
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 5,116 bases
Position: chr19:45,687,454-45,692,569
Accession: 11159
RBP type: canonical RBP
Summary: The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000375798	LSM	PF01423.22	2.3e-18	1	1
ENSP00000465952	LSM	PF01423.22	2.3e-18	1	1
ENSP00000466152	LSM	PF01423.22	2.3e-18	1	1
ENSP00000342374	LSM	PF01423.22	3e-18	1	1
ENSP00000465216	LSM	PF01423.22	3e-18	1	1
ENSP00000465101	LSM	PF01423.22	2.6e-05	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27974620	Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2.	RNA	2017 Mar	Schwer B	doi: 10.1261/rna.059881.116

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000590212	SNRPD2-208	454	-	ENSP00000468247	78 (aa)	-	K7ERG4
ENST00000588301	SNRPD2-206	702	-	ENSP00000465216	118 (aa)	-	P62316
ENST00000587367	SNRPD2-204	596	-	ENSP00000465952	108 (aa)	-	P62316
ENST00000588599	SNRPD2-207	805	-	ENSP00000466152	108 (aa)	-	P62316
ENST00000587579	SNRPD2-205	290	-	-	- (aa)	-	-
ENST00000585392	SNRPD2-203	379	-	ENSP00000465101	54 (aa)	-	K7EJB5
ENST00000342669	SNRPD2-201	901	-	ENSP00000342374	118 (aa)	-	P62316
ENST00000391932	SNRPD2-202	615	-	ENSP00000375798	108 (aa)	-	P62316

Gene Model

Click here to download ENSG00000125743's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125743	Subcutaneous Fat	2E-6	22589738
ENSG00000125743	Subcutaneous Fat	1E-6	22589738

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000125743	rs7245708	19	45692498	C	Subcutaneous adipose tissue	22589738			EFO_0004766
ENSG00000125743	rs7245708	19	45692498	C	Subcutaneous adipose tissue	22589738			EFO_0004766

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125743's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000125743	SNRPD2	76	31.707	ENSG00000170860	LSM3	84	32.222

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125743	SNRPD2	100	99.074	ENSAPOG00000012310	snrpd2	100	98.305	Acanthochromis_polyacanthus
ENSG00000125743	SNRPD2	100	100.000	ENSAMEG00000000818	-	100	100.000	Ailuropoda_melanoleuca
ENSG00000125743	SNRPD2	100	99.074	ENSACIG00000022689	snrpd2	100	99.074	Amphilophus_citrinellus
ENSG00000125743	SNRPD2	100	99.074	ENSAOCG00000024413	snrpd2	100	98.305	Amphiprion_ocellaris
ENSG00000125743	SNRPD2	100	99.074	ENSAPEG00000021711	snrpd2	100	98.305	Amphiprion_percula
ENSG00000125743	SNRPD2	100	99.074	ENSATEG00000000868	snrpd2	98	98.291	Anabas_testudineus
ENSG00000125743	SNRPD2	100	100.000	ENSACAG00000016779	-	99	100.000	Anolis_carolinensis
ENSG00000125743	SNRPD2	100	98.148	ENSANAG00000003063	-	100	97.458	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	96.296	ENSANAG00000005642	-	100	96.296	Aotus_nancymaae
ENSG00000125743	SNRPD2	98	98.113	ENSANAG00000031633	-	98	98.113	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	100.000	ENSANAG00000019777	-	100	100.000	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	100.000	ENSANAG00000017079	-	100	98.305	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	95.763	ENSANAG00000018193	-	100	95.763	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	97.222	ENSANAG00000001612	-	98	97.436	Aotus_nancymaae
ENSG00000125743	SNRPD2	100	99.074	ENSACLG00000001746	snrpd2	100	98.305	Astatotilapia_calliptera
ENSG00000125743	SNRPD2	100	99.153	ENSAMXG00000033526	snrpd2	100	99.153	Astyanax_mexicanus
ENSG00000125743	SNRPD2	100	100.000	ENSBTAG00000012177	SNRPD2	100	100.000	Bos_taurus
ENSG00000125743	SNRPD2	96	83.654	WBGene00004917	snr-4	97	81.579	Caenorhabditis_elegans
ENSG00000125743	SNRPD2	100	98.305	ENSCJAG00000041687	-	100	98.305	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	99.153	ENSCJAG00000019291	-	100	99.153	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	96.610	ENSCJAG00000047147	-	100	96.610	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	100.000	ENSCJAG00000044723	-	100	100.000	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	100.000	ENSCJAG00000012413	-	100	100.000	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	98.305	ENSCJAG00000047157	-	100	98.305	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	98.305	ENSCJAG00000044646	-	100	98.305	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	96.296	ENSCJAG00000044478	-	100	96.296	Callithrix_jacchus
ENSG00000125743	SNRPD2	100	90.678	ENSCAFG00000000634	-	100	90.678	Canis_familiaris
ENSG00000125743	SNRPD2	100	100.000	ENSCAFG00000004403	SNRPD2	100	100.000	Canis_familiaris
ENSG00000125743	SNRPD2	100	100.000	ENSCAFG00020003532	-	98	100.000	Canis_lupus_dingo
ENSG00000125743	SNRPD2	100	90.678	ENSCAFG00020002921	-	100	90.678	Canis_lupus_dingo
ENSG00000125743	SNRPD2	100	100.000	ENSCHIG00000015755	-	98	99.145	Capra_hircus
ENSG00000125743	SNRPD2	97	80.870	ENSTSYG00000031156	-	96	76.522	Carlito_syrichta
ENSG00000125743	SNRPD2	100	100.000	ENSTSYG00000011207	-	100	100.000	Carlito_syrichta
ENSG00000125743	SNRPD2	100	100.000	ENSCAPG00000011695	-	98	100.000	Cavia_aperea
ENSG00000125743	SNRPD2	100	86.441	ENSCAPG00000006559	-	100	85.593	Cavia_aperea
ENSG00000125743	SNRPD2	100	100.000	ENSCPOG00000035154	-	100	100.000	Cavia_porcellus
ENSG00000125743	SNRPD2	100	92.593	ENSCPOG00000025735	-	100	88.983	Cavia_porcellus
ENSG00000125743	SNRPD2	100	100.000	ENSCCAG00000035396	SNRPD2	100	100.000	Cebus_capucinus
ENSG00000125743	SNRPD2	100	97.222	ENSCCAG00000012011	-	100	95.763	Cebus_capucinus
ENSG00000125743	SNRPD2	100	96.296	ENSCCAG00000007393	-	100	96.296	Cebus_capucinus
ENSG00000125743	SNRPD2	100	94.444	ENSCCAG00000030191	-	100	80.508	Cebus_capucinus
ENSG00000125743	SNRPD2	100	96.296	ENSCCAG00000007464	-	100	96.296	Cebus_capucinus
ENSG00000125743	SNRPD2	100	96.296	ENSCCAG00000018327	-	100	96.296	Cebus_capucinus
ENSG00000125743	SNRPD2	100	75.926	ENSCCAG00000020956	-	100	75.424	Cebus_capucinus
ENSG00000125743	SNRPD2	100	100.000	ENSCCAG00000011183	-	100	99.153	Cebus_capucinus
ENSG00000125743	SNRPD2	100	99.153	ENSCATG00000005272	-	100	99.153	Cercocebus_atys
ENSG00000125743	SNRPD2	98	89.655	ENSCATG00000040410	-	99	100.000	Cercocebus_atys
ENSG00000125743	SNRPD2	100	98.305	ENSCATG00000031591	-	100	98.305	Cercocebus_atys
ENSG00000125743	SNRPD2	100	79.630	ENSCLAG00000001183	-	100	78.814	Chinchilla_lanigera
ENSG00000125743	SNRPD2	100	83.333	ENSCLAG00000017381	-	99	83.636	Chinchilla_lanigera
ENSG00000125743	SNRPD2	100	100.000	ENSCLAG00000000931	-	100	100.000	Chinchilla_lanigera
ENSG00000125743	SNRPD2	100	100.000	ENSCSAG00000003157	SNRPD2	100	100.000	Chlorocebus_sabaeus
ENSG00000125743	SNRPD2	100	100.000	ENSCPBG00000007259	SNRPD2	100	100.000	Chrysemys_picta_bellii
ENSG00000125743	SNRPD2	100	79.630	ENSCING00000020031	-	100	78.814	Ciona_intestinalis
ENSG00000125743	SNRPD2	95	82.143	ENSCSAVG00000003527	-	91	82.143	Ciona_savignyi
ENSG00000125743	SNRPD2	100	100.000	ENSCANG00000002575	-	100	100.000	Colobus_angolensis_palliatus
ENSG00000125743	SNRPD2	100	99.153	ENSCANG00000038535	-	100	99.153	Colobus_angolensis_palliatus
ENSG00000125743	SNRPD2	100	72.881	ENSCANG00000035956	-	100	72.881	Colobus_angolensis_palliatus
ENSG00000125743	SNRPD2	100	90.741	ENSCGRG00001003078	-	100	87.288	Cricetulus_griseus_chok1gshd
ENSG00000125743	SNRPD2	100	94.444	ENSCGRG00000011635	-	100	94.872	Cricetulus_griseus_crigri
ENSG00000125743	SNRPD2	100	99.074	ENSCSEG00000002230	snrpd2	100	98.305	Cynoglossus_semilaevis
ENSG00000125743	SNRPD2	100	99.074	ENSCVAG00000010204	SNRPD2	97	98.291	Cyprinodon_variegatus
ENSG00000125743	SNRPD2	100	99.074	ENSCVAG00000014834	snrpd2	100	98.305	Cyprinodon_variegatus
ENSG00000125743	SNRPD2	100	99.153	ENSDARG00000040440	snrpd2	100	99.153	Danio_rerio
ENSG00000125743	SNRPD2	100	100.000	ENSDNOG00000002365	-	92	100.000	Dasypus_novemcinctus
ENSG00000125743	SNRPD2	100	100.000	ENSDORG00000001729	Snrpd2	100	100.000	Dipodomys_ordii
ENSG00000125743	SNRPD2	100	88.182	FBgn0261789	SmD2	98	88.034	Drosophila_melanogaster
ENSG00000125743	SNRPD2	100	81.356	ENSETEG00000002893	-	100	77.966	Echinops_telfairi
ENSG00000125743	SNRPD2	100	94.444	ENSEBUG00000002144	snrpd2	97	93.966	Eptatretus_burgeri
ENSG00000125743	SNRPD2	100	100.000	ENSEASG00005014210	-	100	100.000	Equus_asinus_asinus
ENSG00000125743	SNRPD2	99	73.729	ENSEASG00005016910	-	89	69.492	Equus_asinus_asinus
ENSG00000125743	SNRPD2	100	100.000	ENSECAG00000007824	SNRPD2	96	100.000	Equus_caballus
ENSG00000125743	SNRPD2	99	98.291	ENSELUG00000020393	snrpd2	66	98.291	Esox_lucius
ENSG00000125743	SNRPD2	91	88.785	ENSFCAG00000024879	-	69	89.623	Felis_catus
ENSG00000125743	SNRPD2	100	100.000	ENSFCAG00000022530	-	100	100.000	Felis_catus
ENSG00000125743	SNRPD2	100	100.000	ENSFDAG00000015792	SNRPD2	100	100.000	Fukomys_damarensis
ENSG00000125743	SNRPD2	100	99.074	ENSFHEG00000015591	snrpd2	100	98.305	Fundulus_heteroclitus
ENSG00000125743	SNRPD2	100	99.074	ENSGMOG00000013857	snrpd2	99	98.291	Gadus_morhua
ENSG00000125743	SNRPD2	100	99.074	ENSGAFG00000001246	snrpd2	100	98.305	Gambusia_affinis
ENSG00000125743	SNRPD2	100	97.222	ENSGACG00000006697	snrpd2	99	96.581	Gasterosteus_aculeatus
ENSG00000125743	SNRPD2	77	100.000	ENSGAGG00000017944	SNRPD2	58	100.000	Gopherus_agassizii
ENSG00000125743	SNRPD2	100	100.000	ENSGGOG00000002350	SNRPD2	100	100.000	Gorilla_gorilla
ENSG00000125743	SNRPD2	100	99.074	ENSHBUG00000004073	snrpd2	100	98.305	Haplochromis_burtoni
ENSG00000125743	SNRPD2	100	81.481	ENSHGLG00000017154	-	100	80.508	Heterocephalus_glaber_female
ENSG00000125743	SNRPD2	100	100.000	ENSHGLG00000015364	SNRPD2	100	100.000	Heterocephalus_glaber_female
ENSG00000125743	SNRPD2	100	93.220	ENSHGLG00100020606	-	64	93.220	Heterocephalus_glaber_male
ENSG00000125743	SNRPD2	100	100.000	ENSHGLG00100015694	SNRPD2	100	100.000	Heterocephalus_glaber_male
ENSG00000125743	SNRPD2	100	98.148	ENSHCOG00000010973	snrpd2	100	97.458	Hippocampus_comes
ENSG00000125743	SNRPD2	100	100.000	ENSIPUG00000001053	snrpd2	100	100.000	Ictalurus_punctatus
ENSG00000125743	SNRPD2	100	100.000	ENSSTOG00000024377	SNRPD2	100	100.000	Ictidomys_tridecemlineatus
ENSG00000125743	SNRPD2	100	100.000	ENSJJAG00000002622	Snrpd2	100	100.000	Jaculus_jaculus
ENSG00000125743	SNRPD2	100	99.074	ENSKMAG00000001539	snrpd2	100	98.305	Kryptolebias_marmoratus
ENSG00000125743	SNRPD2	100	98.148	ENSLBEG00000019436	snrpd2	100	97.458	Labrus_bergylta
ENSG00000125743	SNRPD2	100	99.074	ENSLACG00000004720	SNRPD2	100	99.074	Latimeria_chalumnae
ENSG00000125743	SNRPD2	100	99.153	ENSLOCG00000014824	snrpd2	100	99.153	Lepisosteus_oculatus
ENSG00000125743	SNRPD2	100	100.000	ENSLAFG00000004205	-	99	100.000	Loxodonta_africana
ENSG00000125743	SNRPD2	100	99.153	ENSMFAG00000020148	-	100	99.153	Macaca_fascicularis
ENSG00000125743	SNRPD2	100	100.000	ENSMFAG00000045767	-	100	100.000	Macaca_fascicularis
ENSG00000125743	SNRPD2	100	100.000	ENSMFAG00000009957	-	100	97.458	Macaca_fascicularis
ENSG00000125743	SNRPD2	100	99.153	ENSMMUG00000032370	-	100	99.153	Macaca_mulatta
ENSG00000125743	SNRPD2	100	100.000	ENSMMUG00000006937	SNRPD2	100	100.000	Macaca_mulatta
ENSG00000125743	SNRPD2	98	91.379	ENSMMUG00000030518	-	98	91.379	Macaca_mulatta
ENSG00000125743	SNRPD2	100	100.000	ENSMMUG00000032525	-	100	97.458	Macaca_mulatta
ENSG00000125743	SNRPD2	100	98.305	ENSMNEG00000021599	-	100	98.305	Macaca_nemestrina
ENSG00000125743	SNRPD2	100	100.000	ENSMNEG00000039787	-	92	89.623	Macaca_nemestrina
ENSG00000125743	SNRPD2	100	98.148	ENSMNEG00000010649	-	100	96.610	Macaca_nemestrina
ENSG00000125743	SNRPD2	100	100.000	ENSMLEG00000008325	-	100	97.458	Mandrillus_leucophaeus
ENSG00000125743	SNRPD2	100	99.074	ENSMAMG00000013925	snrpd2	100	98.305	Mastacembelus_armatus
ENSG00000125743	SNRPD2	100	99.074	ENSMZEG00005013054	snrpd2	100	98.305	Maylandia_zebra
ENSG00000125743	SNRPD2	100	100.000	ENSMAUG00000018849	Snrpd2	100	100.000	Mesocricetus_auratus
ENSG00000125743	SNRPD2	100	100.000	ENSMICG00000031545	SNRPD2	100	100.000	Microcebus_murinus
ENSG00000125743	SNRPD2	100	100.000	ENSMOCG00000006567	-	100	100.000	Microtus_ochrogaster
ENSG00000125743	SNRPD2	100	94.444	ENSMOCG00000017135	-	100	92.373	Microtus_ochrogaster
ENSG00000125743	SNRPD2	100	100.000	ENSMOCG00000017080	Snrpd2	100	100.000	Microtus_ochrogaster
ENSG00000125743	SNRPD2	100	98.148	ENSMMOG00000004936	snrpd2	100	97.458	Mola_mola
ENSG00000125743	SNRPD2	100	100.000	ENSMODG00000021539	-	99	100.000	Monodelphis_domestica
ENSG00000125743	SNRPD2	100	99.074	ENSMALG00000010608	snrpd2	100	98.305	Monopterus_albus
ENSG00000125743	SNRPD2	100	94.444	MGP_CAROLIEiJ_G0018529	-	100	94.068	Mus_caroli
ENSG00000125743	SNRPD2	100	100.000	MGP_CAROLIEiJ_G0029275	-	100	100.000	Mus_caroli
ENSG00000125743	SNRPD2	100	100.000	ENSMUSG00000040824	Snrpd2	100	100.000	Mus_musculus
ENSG00000125743	SNRPD2	100	100.000	MGP_PahariEiJ_G0021135	-	100	100.000	Mus_pahari
ENSG00000125743	SNRPD2	100	100.000	MGP_SPRETEiJ_G0030359	Snrpd2	100	100.000	Mus_spretus
ENSG00000125743	SNRPD2	100	88.136	MGP_SPRETEiJ_G0019409	-	100	87.288	Mus_spretus
ENSG00000125743	SNRPD2	100	100.000	ENSMPUG00000005733	-	97	100.000	Mustela_putorius_furo
ENSG00000125743	SNRPD2	100	94.915	ENSMLUG00000025417	-	100	94.915	Myotis_lucifugus
ENSG00000125743	SNRPD2	100	100.000	ENSMLUG00000001306	-	100	100.000	Myotis_lucifugus
ENSG00000125743	SNRPD2	87	97.872	ENSMLUG00000030461	-	93	92.661	Myotis_lucifugus
ENSG00000125743	SNRPD2	94	97.297	ENSMLUG00000026353	-	92	97.297	Myotis_lucifugus
ENSG00000125743	SNRPD2	99	82.906	ENSMLUG00000026025	-	99	82.906	Myotis_lucifugus
ENSG00000125743	SNRPD2	100	100.000	ENSNGAG00000010411	-	100	100.000	Nannospalax_galili
ENSG00000125743	SNRPD2	89	87.619	ENSNGAG00000013160	-	68	81.905	Nannospalax_galili
ENSG00000125743	SNRPD2	100	99.074	ENSNBRG00000000805	snrpd2	100	98.305	Neolamprologus_brichardi
ENSG00000125743	SNRPD2	100	100.000	ENSNLEG00000002274	SNRPD2	100	100.000	Nomascus_leucogenys
ENSG00000125743	SNRPD2	100	100.000	ENSMEUG00000012031	-	100	100.000	Notamacropus_eugenii
ENSG00000125743	SNRPD2	100	100.000	ENSOPRG00000008321	-	100	99.153	Ochotona_princeps
ENSG00000125743	SNRPD2	100	100.000	ENSODEG00000008857	-	100	100.000	Octodon_degus
ENSG00000125743	SNRPD2	100	98.305	ENSODEG00000019447	-	100	98.305	Octodon_degus
ENSG00000125743	SNRPD2	100	98.148	ENSODEG00000020094	-	100	97.458	Octodon_degus
ENSG00000125743	SNRPD2	100	100.000	ENSODEG00000020096	-	100	98.305	Octodon_degus
ENSG00000125743	SNRPD2	100	100.000	ENSODEG00000020139	-	100	100.000	Octodon_degus
ENSG00000125743	SNRPD2	97	80.247	ENSODEG00000011751	-	62	98.485	Octodon_degus
ENSG00000125743	SNRPD2	91	90.141	ENSODEG00000008077	-	95	90.141	Octodon_degus
ENSG00000125743	SNRPD2	100	98.148	ENSODEG00000012799	-	95	98.291	Octodon_degus
ENSG00000125743	SNRPD2	100	99.074	ENSONIG00000005406	snrpd2	100	98.305	Oreochromis_niloticus
ENSG00000125743	SNRPD2	100	100.000	ENSOANG00000000813	-	95	100.000	Ornithorhynchus_anatinus
ENSG00000125743	SNRPD2	100	100.000	ENSOCUG00000022402	SNRPD2	100	100.000	Oryctolagus_cuniculus
ENSG00000125743	SNRPD2	100	99.074	ENSORLG00000026725	snrpd2	100	98.305	Oryzias_latipes
ENSG00000125743	SNRPD2	100	99.074	ENSORLG00020011312	snrpd2	100	98.305	Oryzias_latipes_hni
ENSG00000125743	SNRPD2	100	99.074	ENSORLG00015019579	snrpd2	100	98.305	Oryzias_latipes_hsok
ENSG00000125743	SNRPD2	100	99.074	ENSOMEG00000012661	snrpd2	100	99.074	Oryzias_melastigma
ENSG00000125743	SNRPD2	100	100.000	ENSOGAG00000030128	-	100	100.000	Otolemur_garnettii
ENSG00000125743	SNRPD2	100	100.000	ENSOARG00000010203	-	99	100.000	Ovis_aries
ENSG00000125743	SNRPD2	100	100.000	ENSOARG00000016742	-	100	97.458	Ovis_aries
ENSG00000125743	SNRPD2	100	100.000	ENSPPAG00000038031	SNRPD2	100	100.000	Pan_paniscus
ENSG00000125743	SNRPD2	100	100.000	ENSPPRG00000012309	SNRPD2	100	100.000	Panthera_pardus
ENSG00000125743	SNRPD2	100	80.488	ENSPPRG00000000040	-	100	74.797	Panthera_pardus
ENSG00000125743	SNRPD2	100	100.000	ENSPTIG00000006666	-	100	100.000	Panthera_tigris_altaica
ENSG00000125743	SNRPD2	77	88.333	ENSPTIG00000000935	-	69	87.879	Panthera_tigris_altaica
ENSG00000125743	SNRPD2	100	100.000	ENSPTRG00000011162	SNRPD2	100	100.000	Pan_troglodytes
ENSG00000125743	SNRPD2	100	100.000	ENSPANG00000008802	-	100	100.000	Papio_anubis
ENSG00000125743	SNRPD2	100	98.305	ENSPANG00000017743	-	100	98.305	Papio_anubis
ENSG00000125743	SNRPD2	100	99.153	ENSPKIG00000001110	snrpd2	100	99.153	Paramormyrops_kingsleyae
ENSG00000125743	SNRPD2	100	100.000	ENSPSIG00000015823	-	100	100.000	Pelodiscus_sinensis
ENSG00000125743	SNRPD2	100	98.148	ENSPMGG00000016148	snrpd2	100	97.436	Periophthalmus_magnuspinnatus
ENSG00000125743	SNRPD2	100	98.148	ENSPEMG00000009398	-	100	94.915	Peromyscus_maniculatus_bairdii
ENSG00000125743	SNRPD2	100	100.000	ENSPEMG00000004117	-	98	100.000	Peromyscus_maniculatus_bairdii
ENSG00000125743	SNRPD2	100	100.000	ENSPCIG00000022986	SNRPD2	100	100.000	Phascolarctos_cinereus
ENSG00000125743	SNRPD2	100	99.074	ENSPFOG00000016809	snrpd2	100	98.305	Poecilia_formosa
ENSG00000125743	SNRPD2	100	99.074	ENSPLAG00000010725	snrpd2	100	98.305	Poecilia_latipinna
ENSG00000125743	SNRPD2	100	99.074	ENSPMEG00000000107	snrpd2	100	98.305	Poecilia_mexicana
ENSG00000125743	SNRPD2	100	99.074	ENSPREG00000004078	snrpd2	97	99.107	Poecilia_reticulata
ENSG00000125743	SNRPD2	100	100.000	ENSPPYG00000010129	SNRPD2	100	100.000	Pongo_abelii
ENSG00000125743	SNRPD2	100	100.000	ENSPCAG00000016818	SNRPD2	100	100.000	Procavia_capensis
ENSG00000125743	SNRPD2	100	100.000	ENSPCOG00000001429	-	100	100.000	Propithecus_coquereli
ENSG00000125743	SNRPD2	100	100.000	ENSPCOG00000028811	-	100	100.000	Propithecus_coquereli
ENSG00000125743	SNRPD2	100	100.000	ENSPVAG00000001345	-	100	100.000	Pteropus_vampyrus
ENSG00000125743	SNRPD2	100	99.074	ENSPNYG00000011826	snrpd2	100	98.305	Pundamilia_nyererei
ENSG00000125743	SNRPD2	100	99.153	ENSPNAG00000025554	snrpd2	100	99.153	Pygocentrus_nattereri
ENSG00000125743	SNRPD2	100	97.458	ENSRNOG00000048758	Snrpd2l	100	97.458	Rattus_norvegicus
ENSG00000125743	SNRPD2	100	100.000	ENSRNOG00000015844	Snrpd2	100	100.000	Rattus_norvegicus
ENSG00000125743	SNRPD2	100	77.966	ENSRBIG00000032742	-	95	82.143	Rhinopithecus_bieti
ENSG00000125743	SNRPD2	100	89.831	ENSRBIG00000032406	-	100	89.831	Rhinopithecus_bieti
ENSG00000125743	SNRPD2	100	100.000	ENSRBIG00000040969	SNRPD2	100	100.000	Rhinopithecus_bieti
ENSG00000125743	SNRPD2	100	100.000	ENSRROG00000034764	SNRPD2	100	100.000	Rhinopithecus_roxellana
ENSG00000125743	SNRPD2	100	87.288	ENSRROG00000030974	-	81	100.000	Rhinopithecus_roxellana
ENSG00000125743	SNRPD2	93	60.000	YLR275W	SMD2	96	52.212	Saccharomyces_cerevisiae
ENSG00000125743	SNRPD2	100	99.153	ENSSBOG00000017764	-	100	99.153	Saimiri_boliviensis_boliviensis
ENSG00000125743	SNRPD2	100	97.458	ENSSBOG00000019992	-	81	97.458	Saimiri_boliviensis_boliviensis
ENSG00000125743	SNRPD2	100	100.000	ENSSBOG00000035164	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000125743	SNRPD2	100	100.000	ENSSBOG00000009827	-	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000125743	SNRPD2	100	99.074	ENSSHAG00000003772	-	99	99.145	Sarcophilus_harrisii
ENSG00000125743	SNRPD2	100	99.153	ENSSFOG00015022535	snrpd2	100	99.153	Scleropages_formosus
ENSG00000125743	SNRPD2	100	100.000	ENSSFOG00015016069	-	100	100.000	Scleropages_formosus
ENSG00000125743	SNRPD2	100	98.148	ENSSMAG00000003422	snrpd2	100	97.458	Scophthalmus_maximus
ENSG00000125743	SNRPD2	100	99.074	ENSSDUG00000005519	snrpd2	100	98.305	Seriola_dumerili
ENSG00000125743	SNRPD2	100	99.074	ENSSLDG00000009397	snrpd2	100	98.305	Seriola_lalandi_dorsalis
ENSG00000125743	SNRPD2	100	100.000	ENSSARG00000009167	-	100	100.000	Sorex_araneus
ENSG00000125743	SNRPD2	100	100.000	ENSSPUG00000003011	-	100	100.000	Sphenodon_punctatus
ENSG00000125743	SNRPD2	100	99.074	ENSSPAG00000015767	snrpd2	100	98.305	Stegastes_partitus
ENSG00000125743	SNRPD2	77	75.000	ENSSSCG00000040417	-	75	73.333	Sus_scrofa
ENSG00000125743	SNRPD2	100	100.000	ENSSSCG00000033500	SNRPD2	100	100.000	Sus_scrofa
ENSG00000125743	SNRPD2	100	97.222	ENSTRUG00000023014	snrpd2	100	96.610	Takifugu_rubripes
ENSG00000125743	SNRPD2	85	99.000	ENSTNIG00000011736	snrpd2	92	99.000	Tetraodon_nigroviridis
ENSG00000125743	SNRPD2	100	100.000	ENSTBEG00000001752	SNRPD2	100	100.000	Tupaia_belangeri
ENSG00000125743	SNRPD2	100	100.000	ENSTTRG00000014299	-	100	100.000	Tursiops_truncatus
ENSG00000125743	SNRPD2	100	100.000	ENSUAMG00000023173	SNRPD2	100	100.000	Ursus_americanus
ENSG00000125743	SNRPD2	78	76.087	ENSUAMG00000022454	-	62	75.000	Ursus_americanus
ENSG00000125743	SNRPD2	100	100.000	ENSUMAG00000023685	-	100	100.000	Ursus_maritimus
ENSG00000125743	SNRPD2	78	76.087	ENSUMAG00000001547	-	62	75.000	Ursus_maritimus
ENSG00000125743	SNRPD2	100	100.000	ENSVVUG00000003181	-	98	100.000	Vulpes_vulpes
ENSG00000125743	SNRPD2	100	91.525	ENSVVUG00000016748	-	100	91.525	Vulpes_vulpes
ENSG00000125743	SNRPD2	100	99.074	ENSXETG00000002173	snrpd2	100	99.145	Xenopus_tropicalis
ENSG00000125743	SNRPD2	100	99.074	ENSXCOG00000001082	snrpd2	93	98.291	Xiphophorus_couchianus
ENSG00000125743	SNRPD2	100	99.074	ENSXMAG00000001018	snrpd2	100	98.305	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000245	spliceosomal complex assembly	7527560.	TAS	Process
GO:0000387	spliceosomal snRNP assembly	21873635.	IBA	Process
GO:0000387	spliceosomal snRNP assembly	18984161.	IDA	Process
GO:0000387	spliceosomal snRNP assembly	-	TAS	Process
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	28076346.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	9417867.11714716.11748230.12065586.14667819.15231747.18984161.22365833.25416956.30021884.	IPI	Function
GO:0005634	nucleus	28076346.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005681	spliceosomal complex	1701240.	TAS	Component
GO:0005682	U5 snRNP	21873635.	IBA	Component
GO:0005685	U1 snRNP	21873635.	IBA	Component
GO:0005685	U1 snRNP	21113136.25555158.	IDA	Component
GO:0005686	U2 snRNP	21873635.	IBA	Component
GO:0005687	U4 snRNP	21516107.	IDA	Component
GO:0005689	U12-type spliceosomal complex	15146077.	IDA	Component
GO:0005829	cytosol	18984161.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0008380	RNA splicing	1701240.	TAS	Process
GO:0030532	small nuclear ribonucleoprotein complex	1701240.	TAS	Component
GO:0034709	methylosome	18984161.	IDA	Component
GO:0034715	pICln-Sm protein complex	18984161.	IDA	Component
GO:0034719	SMN-Sm protein complex	18984161.	IDA	Component
GO:0046540	U4/U6 x U5 tri-snRNP complex	21873635.	IBA	Component
GO:0046540	U4/U6 x U5 tri-snRNP complex	26912367.	IDA	Component
GO:0051170	import into nucleus	-	TAS	Process
GO:0070062	extracellular exosome	20458337.	HDA	Component
GO:0071005	U2-type precatalytic spliceosome	28781166.	IDA	Component
GO:0071007	U2-type catalytic step 2 spliceosome	28076346.	IDA	Component
GO:0071013	catalytic step 2 spliceosome	21873635.	IBA	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	45688513	Missense_Mutation	NA	R19Q	0.17	LSM
BLCA	chr19	45687694	Silent	novel	E72E	0.27
BLCA	chr19	45689327	Intron	novel		0.38
BLCA	chr19	45691949	5'UTR	novel		0.14
BLCA	chr19	45687610	Silent	novel	F100F	0.18
BLCA	chr19	45688473	Silent	novel	L32L	0.21
BLCA	chr19	45691983	5'UTR	novel		0.28
BRCA	chr19	45687489	3'UTR	novel		0.1
BRCA	chr19	45688395	Silent	NA	A58A	0.11
BRCA	chr19	45687706	Silent	NA	E68E	0.48
BRCA	chr19	45687567	Missense_Mutation	NA	I115V	0.25
BRCA	chr19	45691886	Frame_Shift_Ins	novel	M1?	0.06	LSM
BRCA	chr19	45692137	5'UTR	novel		0.45
CESC	chr19	45687596	Missense_Mutation	NA	S105L	0.38
CESC	chr19	45688518	Silent	novel	Q17Q	0.43
CESC	chr19	45688557	Silent	NA	L4L	0.25
CESC	chr19	45689281	Intron	novel		0.17
COAD	chr19	45688559	Missense_Mutation	novel	L4V	0.06	LSM
COAD	chr19	45687589	Silent	rs759353268	I107I	0.36
COAD	chr19	45692033	5'UTR	novel		0.17
COAD	chr19	45688404	Silent	rs768063363	R55R	0.28
COAD	chr19	45691929	5'UTR	novel		0.24
DLBC	chr19	45688391	Missense_Mutation	novel	D60N	0.37
ESCA	chr19	45691924	5'UTR	novel		0.16
ESCA	chr19	45687691	Missense_Mutation	novel	M73I	0.23
ESCA	chr19	45691949	5'UTR	novel		0.19
ESCA	chr19	45687700	Silent	rs751917445	V70V	0.28
GBM	chr19	45691949	5'UTR	novel		0.27
HNSC	chr19	45687577	Silent	novel	R111R	0.17
HNSC	chr19	45691983	5'UTR	novel		0.34
HNSC	chr19	45689287	Intron	novel		0.25
HNSC	chr19	45692007	5'UTR	novel		0.24
HNSC	chr19	45688528	Missense_Mutation	novel	E14A	0.13	LSM
KIRC	chr19	45688386	Splice_Site	novel	X61_splice	0.25
LUAD	chr19	45691942	5'UTR	novel		0.27
LUSC	chr19	45692013	5'UTR	novel		0.06
LUSC	chr19	45687684	Missense_Mutation	NA	E76K	0.07
LUSC	chr19	45691964	5'UTR	novel		0.41
LUSC	chr19	45691978	5'UTR	novel		0.28
OV	chr19	45689307	Intron	novel		0.11
PRAD	chr19	45688511	Missense_Mutation	NA	E20Q	0.37	LSM
SKCM	chr19	45691969	5'UTR	novel		0.39
SKCM	chr19	45691983	5'UTR	novel		0.32
SKCM	chr19	45691963	5'UTR	novel		0.3
SKCM	chr19	45691963	5'UTR	novel		0.39
SKCM	chr19	45691966	5'UTR	novel		0.06
SKCM	chr19	45691963	5'UTR	novel		0.28
SKCM	chr19	45691966	5'UTR	novel		0.24
SKCM	chr19	45691984	5'UTR	novel		0.29
SKCM	chr19	45689233	Intron	novel		0.07
SKCM	chr19	45691983	5'UTR	novel		0.24
SKCM	chr19	45691983	5'UTR	novel		0.33
SKCM	chr19	45687603	Missense_Mutation	NA	G103W	0.42
SKCM	chr19	45691966	5'UTR	novel		0.1
SKCM	chr19	45691969	5'UTR	novel		0.29
SKCM	chr19	45691983	5'UTR	novel		0.16
SKCM	chr19	45691945	5'UTR	novel		0.29
SKCM	chr19	45691983	5'UTR	novel		0.32
SKCM	chr19	45691974	5'UTR	novel		0.59
SKCM	chr19	45691983	5'UTR	novel		0.47
STAD	chr19	45687581	Missense_Mutation	novel	L110P	0.23
STAD	chr19	45687668	Missense_Mutation	NA	G81D	0.06
STAD	chr19	45688562	Missense_Mutation	NA	L3I	0.09	LSM
STAD	chr19	45687656	Missense_Mutation	NA	K85R	0.14
STAD	chr19	45687564	Missense_Mutation	rs748374764	A116T	0.11
STAD	chr19	45687680	Missense_Mutation	NA	V77A	0.57
STAD	chr19	45687463	3'UTR	novel		0.41
STAD	chr19	45687463	3'UTR	novel		0.37
THYM	chr19	45687711	Missense_Mutation	novel	L67M	0.19
UCEC	chr19	45687456	3'UTR	novel		0.37
UCEC	chr19	45687487	3'UTR	novel		0.34
UCEC	chr19	45688510	Missense_Mutation	NA	E20G	0.23	LSM
UCEC	chr19	45691952	5'UTR	novel		0.08
UCEC	chr19	45689295	Intron	novel		0.73
UCEC	chr19	45687632	Missense_Mutation	novel	D93G	0.33
UCEC	chr19	45688391	Missense_Mutation	novel	D60N	0.32
UCEC	chr19	45687548	3'UTR	rs1802704		0.54
UCEC	chr19	45689277	Intron	rs761279646		0.34
UCEC	chr19	45692012	5'UTR	novel		0.04
UCEC	chr19	45687658	Missense_Mutation	novel	K84N	0.44
UCEC	chr19	45688391	Missense_Mutation	novel	D60N	0.08
UCEC	chr19	45692094	5'UTR	novel		0.38
UCEC	chr19	45687463	3'UTR	novel		0.43
UCEC	chr19	45687467	3'UTR	novel		0.4
UCEC	chr19	45688404	Silent	rs768063363	R55R	0.42
UCEC	chr19	45692057	5'UTR	novel		0.37
UCEC	chr19	45691909	5'UTR	novel		0.32
UCEC	chr19	45687547	3'UTR	novel		0.43

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0746	0.027508
KIRP	DEL	0.0486	0.054726
READ	DEL	0.0667	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1964	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00012	Kaplan-Meier Survival Analysis
MESO	0.00052	Kaplan-Meier Survival Analysis
ACC	0.0037	Kaplan-Meier Survival Analysis
SKCM	0.03	Kaplan-Meier Survival Analysis
LUSC	0.028	Kaplan-Meier Survival Analysis
TGCT	0.026	Kaplan-Meier Survival Analysis
KIRP	0.0034	Kaplan-Meier Survival Analysis
PCPG	0.018	Kaplan-Meier Survival Analysis
BLCA	0.018	Kaplan-Meier Survival Analysis
UCEC	0.042	Kaplan-Meier Survival Analysis
LIHC	0.0021	Kaplan-Meier Survival Analysis
LGG	0.00014	Kaplan-Meier Survival Analysis
LUAD	0.0055	Kaplan-Meier Survival Analysis
UVM	0.0076	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742