EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125755 (Gene tree)
Gene ID: 8189
Gene Symbol: SYMPK
Alias: SYM|SPK
Full Name: symplekin
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 47,881 bases
Position: chr19:45,815,410-45,863,290
Accession: 22935
RBP type: canonical RBP
Summary: This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000245934	Symplekin_C	PF12295.8	1.9e-73	1	1
ENSP00000478599	Symplekin_C	PF12295.8	4.6e-19	1	1
ENSP00000479480	Symplekin_C	PF12295.8	4.6e-19	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
25921069	Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors.	Mol Cell	2015 Jun 4	Misra A	doi: 10.1016/j.molcel.2015.03.016
18158581	Protein factors in pre-mRNA 3'-end processing.	Cell Mol Life Sci	2008 Apr	Mandel CR	-
20634199	The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs.	Nucleic Acids Res	2010 Nov	Ruepp MD	doi: 10.1093/nar/gkq613

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000596518	SYMPK-206	592	-	-	- (aa)	-	-
ENST00000594293	SYMPK-205	623	-	ENSP00000471770	115 (aa)	-	M0R1C2
ENST00000600237	SYMPK-215	5164	-	ENSP00000473136	673 (aa)	-	M0R3C7
ENST00000601600	SYMPK-217	560	-	ENSP00000470977	50 (aa)	-	M0R039
ENST00000599814	SYMPK-214	6537	-	ENSP00000478599	1058 (aa)	-	A0A087WUE9
ENST00000593899	SYMPK-203	558	-	-	- (aa)	-	-
ENST00000593959	SYMPK-204	546	-	-	- (aa)	-	-
ENST00000602061	SYMPK-218	503	-	ENSP00000469296	142 (aa)	-	M0QXP5
ENST00000599460	SYMPK-213	5449	-	ENSP00000479480	1058 (aa)	-	A0A087WUE9
ENST00000598364	SYMPK-211	995	-	-	- (aa)	-	-
ENST00000598155	SYMPK-209	1603	-	-	- (aa)	-	-
ENST00000601582	SYMPK-216	544	-	-	- (aa)	-	-
ENST00000593504	SYMPK-202	5107	-	-	- (aa)	-	-
ENST00000598059	SYMPK-208	611	-	ENSP00000471694	137 (aa)	-	M0R180
ENST00000598896	SYMPK-212	1899	-	-	- (aa)	-	-
ENST00000596824	SYMPK-207	653	-	ENSP00000470957	95 (aa)	-	M0R033
ENST00000245934	SYMPK-201	4195	XM_005259286	ENSP00000245934	1274 (aa)	XP_005259343	Q92797
ENST00000598329	SYMPK-210	1000	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000125755's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG
hsa04530	Tight junction	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125755	Colonic Neoplasms	5E-7	28295283
ENSG00000125755	Colorectal Neoplasms	9E-7	28295283
ENSG00000125755	Colonic Neoplasms	2E-8	28295283

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000125755	rs56848936	19	45818249	A	Colon cancer	28295283	[1.37-1.92]	1.64	EFO_0004288
ENSG00000125755	rs56848936	19	45818249	A	Colon cancer	28295283	[1.43-2.22]	1.79	EFO_0004288
ENSG00000125755	rs56848936	19	45818249	A	Colorectal cancer	28295283	[1.25-1.69]	1.45	EFO_0005842
ENSG00000125755	rs76793172	19	45856536	T	Eosinophil counts	27863252	[0.04-0.065] unit decrease	0.05245408	EFO_0004842
ENSG00000125755	rs8102876	19	45829584	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000125755	rs62109854	19	45847117	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125755's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125755	SYMPK	83	83.051	ENSAPOG00000015934	sympk	97	73.870	Acanthochromis_polyacanthus
ENSG00000125755	SYMPK	100	98.592	ENSAMEG00000000680	SYMPK	100	97.096	Ailuropoda_melanoleuca
ENSG00000125755	SYMPK	81	81.818	ENSACIG00000006357	sympk	92	74.840	Amphilophus_citrinellus
ENSG00000125755	SYMPK	91	77.907	ENSAOCG00000024124	sympk	92	74.656	Amphiprion_ocellaris
ENSG00000125755	SYMPK	91	77.907	ENSAPEG00000003465	sympk	90	74.301	Amphiprion_percula
ENSG00000125755	SYMPK	87	78.906	ENSATEG00000008472	sympk	91	74.350	Anabas_testudineus
ENSG00000125755	SYMPK	83	93.671	ENSACAG00000004126	SYMPK	99	78.956	Anolis_carolinensis
ENSG00000125755	SYMPK	100	99.296	ENSANAG00000021087	SYMPK	100	99.200	Aotus_nancymaae
ENSG00000125755	SYMPK	88	78.906	ENSACLG00000001813	sympk	91	74.506	Astatotilapia_calliptera
ENSG00000125755	SYMPK	100	75.352	ENSAMXG00000013677	sympk	92	73.810	Astyanax_mexicanus
ENSG00000125755	SYMPK	100	98.592	ENSBTAG00000012101	SYMPK	100	96.468	Bos_taurus
ENSG00000125755	SYMPK	90	30.294	WBGene00017797	symk-1	80	30.541	Caenorhabditis_elegans
ENSG00000125755	SYMPK	100	99.296	ENSCJAG00000012172	SYMPK	99	97.460	Callithrix_jacchus
ENSG00000125755	SYMPK	100	98.592	ENSCAFG00000004376	SYMPK	100	97.338	Canis_familiaris
ENSG00000125755	SYMPK	100	98.592	ENSCAFG00020001815	SYMPK	100	97.338	Canis_lupus_dingo
ENSG00000125755	SYMPK	100	98.592	ENSCHIG00000026784	SYMPK	100	96.939	Capra_hircus
ENSG00000125755	SYMPK	100	98.592	ENSTSYG00000006268	SYMPK	99	96.873	Carlito_syrichta
ENSG00000125755	SYMPK	100	99.296	ENSCAPG00000005112	SYMPK	96	95.403	Cavia_aperea
ENSG00000125755	SYMPK	100	99.296	ENSCPOG00000010434	SYMPK	100	91.660	Cavia_porcellus
ENSG00000125755	SYMPK	100	99.296	ENSCCAG00000036309	SYMPK	100	99.200	Cebus_capucinus
ENSG00000125755	SYMPK	100	100.000	ENSCATG00000045107	SYMPK	100	100.000	Cercocebus_atys
ENSG00000125755	SYMPK	100	100.000	ENSCLAG00000001206	SYMPK	100	96.627	Chinchilla_lanigera
ENSG00000125755	SYMPK	100	100.000	ENSCSAG00000003115	SYMPK	100	99.294	Chlorocebus_sabaeus
ENSG00000125755	SYMPK	93	92.834	ENSCHOG00000012456	SYMPK	81	100.000	Choloepus_hoffmanni
ENSG00000125755	SYMPK	100	88.811	ENSCPBG00000007170	SYMPK	98	84.455	Chrysemys_picta_bellii
ENSG00000125755	SYMPK	80	68.421	ENSCING00000021232	-	96	49.153	Ciona_intestinalis
ENSG00000125755	SYMPK	80	67.105	ENSCSAVG00000005154	-	100	48.071	Ciona_savignyi
ENSG00000125755	SYMPK	100	100.000	ENSCANG00000040907	SYMPK	100	100.000	Colobus_angolensis_palliatus
ENSG00000125755	SYMPK	100	99.296	ENSCGRG00001010086	Sympk	100	91.713	Cricetulus_griseus_chok1gshd
ENSG00000125755	SYMPK	86	79.508	ENSCSEG00000016802	sympk	91	74.170	Cynoglossus_semilaevis
ENSG00000125755	SYMPK	81	83.117	ENSCVAG00000015093	sympk	81	73.902	Cyprinodon_variegatus
ENSG00000125755	SYMPK	90	81.250	ENSDARG00000059553	sympk	88	74.091	Danio_rerio
ENSG00000125755	SYMPK	100	97.183	ENSDNOG00000016149	SYMPK	98	95.501	Dasypus_novemcinctus
ENSG00000125755	SYMPK	96	34.058	FBgn0037371	Sym	95	36.729	Drosophila_melanogaster
ENSG00000125755	SYMPK	64	95.082	ENSETEG00000015995	-	54	95.541	Echinops_telfairi
ENSG00000125755	SYMPK	81	77.922	ENSEBUG00000000387	sympk	89	62.558	Eptatretus_burgeri
ENSG00000125755	SYMPK	100	98.592	ENSEASG00005014227	SYMPK	100	97.176	Equus_asinus_asinus
ENSG00000125755	SYMPK	100	98.592	ENSECAG00000008163	SYMPK	100	97.176	Equus_caballus
ENSG00000125755	SYMPK	100	90.000	ENSEEUG00000000270	-	81	93.333	Erinaceus_europaeus
ENSG00000125755	SYMPK	100	79.720	ENSELUG00000000850	sympk	88	75.380	Esox_lucius
ENSG00000125755	SYMPK	100	98.927	ENSFCAG00000007337	SYMPK	100	97.331	Felis_catus
ENSG00000125755	SYMPK	100	99.296	ENSFDAG00000011272	SYMPK	100	96.314	Fukomys_damarensis
ENSG00000125755	SYMPK	83	83.898	ENSFHEG00000010274	sympk	90	75.000	Fundulus_heteroclitus
ENSG00000125755	SYMPK	81	83.117	ENSGMOG00000002357	sympk	99	72.970	Gadus_morhua
ENSG00000125755	SYMPK	85	80.000	ENSGAFG00000010976	sympk	91	75.158	Gambusia_affinis
ENSG00000125755	SYMPK	92	75.373	ENSGACG00000002735	sympk	98	74.319	Gasterosteus_aculeatus
ENSG00000125755	SYMPK	96	82.796	ENSGAGG00000012538	-	88	84.885	Gopherus_agassizii
ENSG00000125755	SYMPK	100	100.000	ENSGGOG00000003410	SYMPK	98	99.608	Gorilla_gorilla
ENSG00000125755	SYMPK	88	78.906	ENSHBUG00000023564	sympk	91	74.596	Haplochromis_burtoni
ENSG00000125755	SYMPK	100	99.296	ENSHGLG00000005228	SYMPK	100	91.843	Heterocephalus_glaber_female
ENSG00000125755	SYMPK	100	99.296	ENSHGLG00100018571	SYMPK	100	91.393	Heterocephalus_glaber_male
ENSG00000125755	SYMPK	81	80.519	ENSHCOG00000017400	sympk	91	70.394	Hippocampus_comes
ENSG00000125755	SYMPK	100	73.239	ENSIPUG00000024020	SYMPK	90	73.925	Ictalurus_punctatus
ENSG00000125755	SYMPK	100	99.296	ENSSTOG00000001534	SYMPK	100	97.017	Ictidomys_tridecemlineatus
ENSG00000125755	SYMPK	100	98.592	ENSJJAG00000006633	Sympk	100	94.910	Jaculus_jaculus
ENSG00000125755	SYMPK	86	83.607	ENSKMAG00000016292	sympk	98	70.515	Kryptolebias_marmoratus
ENSG00000125755	SYMPK	83	82.278	ENSLBEG00000027913	sympk	99	69.980	Labrus_bergylta
ENSG00000125755	SYMPK	100	78.621	ENSLACG00000016497	SYMPK	100	71.593	Latimeria_chalumnae
ENSG00000125755	SYMPK	100	98.592	ENSLAFG00000008726	SYMPK	100	96.630	Loxodonta_africana
ENSG00000125755	SYMPK	81	100.000	ENSMFAG00000030093	-	90	97.605	Macaca_fascicularis
ENSG00000125755	SYMPK	100	100.000	ENSMMUG00000015428	SYMPK	100	100.000	Macaca_mulatta
ENSG00000125755	SYMPK	100	100.000	ENSMNEG00000019439	SYMPK	100	100.000	Macaca_nemestrina
ENSG00000125755	SYMPK	100	100.000	ENSMLEG00000040508	SYMPK	100	100.000	Mandrillus_leucophaeus
ENSG00000125755	SYMPK	83	82.203	ENSMAMG00000010486	sympk	90	74.345	Mastacembelus_armatus
ENSG00000125755	SYMPK	88	78.906	ENSMZEG00005014146	sympk	91	74.506	Maylandia_zebra
ENSG00000125755	SYMPK	100	99.296	ENSMAUG00000015657	Sympk	100	92.338	Mesocricetus_auratus
ENSG00000125755	SYMPK	100	98.000	ENSMICG00000001871	SYMPK	100	97.600	Microcebus_murinus
ENSG00000125755	SYMPK	100	99.296	ENSMOCG00000008388	Sympk	100	93.297	Microtus_ochrogaster
ENSG00000125755	SYMPK	87	81.818	ENSMMOG00000019227	sympk	94	73.073	Mola_mola
ENSG00000125755	SYMPK	99	95.035	ENSMODG00000021534	SYMPK	96	90.187	Monodelphis_domestica
ENSG00000125755	SYMPK	88	69.607	ENSMALG00000008347	sympk	96	69.926	Monopterus_albus
ENSG00000125755	SYMPK	100	98.592	MGP_CAROLIEiJ_G0029267	Sympk	100	93.375	Mus_caroli
ENSG00000125755	SYMPK	100	98.592	ENSMUSG00000023118	Sympk	100	92.564	Mus_musculus
ENSG00000125755	SYMPK	100	99.296	MGP_PahariEiJ_G0021127	Sympk	100	94.136	Mus_pahari
ENSG00000125755	SYMPK	100	98.592	MGP_SPRETEiJ_G0030351	-	100	93.380	Mus_spretus
ENSG00000125755	SYMPK	100	98.592	ENSMPUG00000005505	SYMPK	100	95.455	Mustela_putorius_furo
ENSG00000125755	SYMPK	83	97.468	ENSMLUG00000001359	SYMPK	100	92.147	Myotis_lucifugus
ENSG00000125755	SYMPK	100	98.592	ENSNGAG00000000820	Sympk	100	94.914	Nannospalax_galili
ENSG00000125755	SYMPK	81	81.818	ENSNBRG00000018101	sympk	92	75.187	Neolamprologus_brichardi
ENSG00000125755	SYMPK	100	100.000	ENSNLEG00000002369	SYMPK	100	85.927	Nomascus_leucogenys
ENSG00000125755	SYMPK	100	92.000	ENSMEUG00000003866	SYMPK	81	92.982	Notamacropus_eugenii
ENSG00000125755	SYMPK	100	98.592	ENSOPRG00000009967	SYMPK	100	93.740	Ochotona_princeps
ENSG00000125755	SYMPK	100	99.296	ENSODEG00000007519	SYMPK	100	96.471	Octodon_degus
ENSG00000125755	SYMPK	85	82.500	ENSONIG00000016802	sympk	96	74.234	Oreochromis_niloticus
ENSG00000125755	SYMPK	100	98.592	ENSOCUG00000005511	SYMPK	92	95.980	Oryctolagus_cuniculus
ENSG00000125755	SYMPK	85	81.197	ENSORLG00000015338	sympk	96	74.473	Oryzias_latipes
ENSG00000125755	SYMPK	82	82.143	ENSORLG00020004402	sympk	90	75.572	Oryzias_latipes_hni
ENSG00000125755	SYMPK	85	80.328	ENSORLG00015005712	sympk	90	75.663	Oryzias_latipes_hsok
ENSG00000125755	SYMPK	80	83.186	ENSOMEG00000022561	sympk	90	75.276	Oryzias_melastigma
ENSG00000125755	SYMPK	100	99.296	ENSOGAG00000013483	SYMPK	100	97.488	Otolemur_garnettii
ENSG00000125755	SYMPK	100	98.592	ENSOARG00000010349	SYMPK	100	91.342	Ovis_aries
ENSG00000125755	SYMPK	100	100.000	ENSPPAG00000043204	SYMPK	100	99.843	Pan_paniscus
ENSG00000125755	SYMPK	100	97.887	ENSPPRG00000004282	SYMPK	100	97.331	Panthera_pardus
ENSG00000125755	SYMPK	100	97.887	ENSPTIG00000015420	SYMPK	100	94.898	Panthera_tigris_altaica
ENSG00000125755	SYMPK	100	100.000	ENSPTRG00000011169	SYMPK	100	99.843	Pan_troglodytes
ENSG00000125755	SYMPK	100	100.000	ENSPANG00000019930	SYMPK	100	100.000	Papio_anubis
ENSG00000125755	SYMPK	100	81.818	ENSPKIG00000017132	sympk	96	72.987	Paramormyrops_kingsleyae
ENSG00000125755	SYMPK	100	100.000	ENSPEMG00000007564	Sympk	100	93.682	Peromyscus_maniculatus_bairdii
ENSG00000125755	SYMPK	81	81.818	ENSPMAG00000004936	sympk	100	65.679	Petromyzon_marinus
ENSG00000125755	SYMPK	99	95.745	ENSPCIG00000024476	SYMPK	99	88.337	Phascolarctos_cinereus
ENSG00000125755	SYMPK	85	80.000	ENSPFOG00000001194	sympk	90	75.272	Poecilia_formosa
ENSG00000125755	SYMPK	85	80.000	ENSPLAG00000012995	sympk	90	75.181	Poecilia_latipinna
ENSG00000125755	SYMPK	85	80.000	ENSPMEG00000008099	sympk	90	75.181	Poecilia_mexicana
ENSG00000125755	SYMPK	85	79.167	ENSPREG00000006176	sympk	90	75.431	Poecilia_reticulata
ENSG00000125755	SYMPK	100	100.000	ENSPPYG00000010135	SYMPK	99	99.281	Pongo_abelii
ENSG00000125755	SYMPK	100	94.000	ENSPCAG00000005182	SYMPK	94	90.738	Procavia_capensis
ENSG00000125755	SYMPK	100	98.592	ENSPCOG00000023740	SYMPK	100	98.400	Propithecus_coquereli
ENSG00000125755	SYMPK	100	97.183	ENSPVAG00000001355	SYMPK	100	96.045	Pteropus_vampyrus
ENSG00000125755	SYMPK	88	79.688	ENSPNYG00000011455	sympk	90	74.686	Pundamilia_nyererei
ENSG00000125755	SYMPK	100	81.690	ENSPNAG00000016505	sympk	89	75.560	Pygocentrus_nattereri
ENSG00000125755	SYMPK	100	100.000	ENSRNOG00000014353	Sympk	100	93.765	Rattus_norvegicus
ENSG00000125755	SYMPK	100	100.000	ENSRBIG00000040963	SYMPK	100	100.000	Rhinopithecus_bieti
ENSG00000125755	SYMPK	100	100.000	ENSRROG00000024834	SYMPK	100	99.137	Rhinopithecus_roxellana
ENSG00000125755	SYMPK	100	99.296	ENSSBOG00000034497	SYMPK	100	99.200	Saimiri_boliviensis_boliviensis
ENSG00000125755	SYMPK	99	96.491	ENSSHAG00000003139	SYMPK	99	91.154	Sarcophilus_harrisii
ENSG00000125755	SYMPK	100	81.119	ENSSFOG00015006974	sympk	90	76.004	Scleropages_formosus
ENSG00000125755	SYMPK	79	87.037	ENSSMAG00000018130	sympk	72	74.615	Scophthalmus_maximus
ENSG00000125755	SYMPK	80	86.726	ENSSDUG00000007092	sympk	91	74.619	Seriola_dumerili
ENSG00000125755	SYMPK	80	86.726	ENSSLDG00000014774	sympk	96	72.374	Seriola_lalandi_dorsalis
ENSG00000125755	SYMPK	100	96.000	ENSSARG00000004274	-	66	100.000	Sorex_araneus
ENSG00000125755	SYMPK	100	88.276	ENSSPUG00000002789	SYMPK	96	82.688	Sphenodon_punctatus
ENSG00000125755	SYMPK	86	81.148	ENSSPAG00000000854	sympk	90	74.729	Stegastes_partitus
ENSG00000125755	SYMPK	100	98.592	ENSSSCG00000003093	SYMPK	100	97.174	Sus_scrofa
ENSG00000125755	SYMPK	87	83.065	ENSTRUG00000010202	sympk	91	74.214	Takifugu_rubripes
ENSG00000125755	SYMPK	87	83.065	ENSTNIG00000017855	sympk	99	73.590	Tetraodon_nigroviridis
ENSG00000125755	SYMPK	100	97.183	ENSTBEG00000000454	SYMPK	88	94.805	Tupaia_belangeri
ENSG00000125755	SYMPK	100	98.592	ENSTTRG00000014311	SYMPK	100	88.706	Tursiops_truncatus
ENSG00000125755	SYMPK	100	98.592	ENSUAMG00000022272	SYMPK	100	94.431	Ursus_americanus
ENSG00000125755	SYMPK	100	98.592	ENSUMAG00000023698	SYMPK	100	97.253	Ursus_maritimus
ENSG00000125755	SYMPK	100	98.592	ENSVVUG00000003024	SYMPK	99	97.627	Vulpes_vulpes
ENSG00000125755	SYMPK	92	83.077	ENSXETG00000024453	sympk	94	72.743	Xenopus_tropicalis
ENSG00000125755	SYMPK	81	81.818	ENSXCOG00000015368	sympk	100	74.468	Xiphophorus_couchianus
ENSG00000125755	SYMPK	85	80.000	ENSXMAG00000005737	sympk	90	75.272	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0005515	protein binding	14707147.18288197.18688255.20861839.26496610.	IPI	Function
GO:0005654	nucleoplasm	8769423.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	8769423.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0005923	bicellular tight junction	-	IEA	Component
GO:0006369	termination of RNA polymerase II transcription	-	TAS	Process
GO:0006378	mRNA polyadenylation	20861839.	IMP	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0007155	cell adhesion	-	IEA	Process
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0032091	negative regulation of protein binding	29158257.	IMP	Process
GO:0035307	positive regulation of protein dephosphorylation	20861839.	IDA	Process
GO:0097165	nuclear stress granule	14707147.	IDA	Component