EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125812 (Gene tree)
Gene ID: 64412
Gene Symbol: GZF1
Alias: dJ322G13.2|ZBTB23|ZNF336
Full Name: GDNF inducible zinc finger protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 11,425 bases
Position: chr20:23,361,639-23,373,063
Accession: 15808
RBP type: canonical RBP
Summary: GZF1 (GDNF Inducible Zinc Finger Protein 1) is a Protein Coding gene. Diseases associated with GZF1 include Joint Laxity, Short Stature, And Myopia and Larsen Syndrome. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific. An important paralog of this gene is ZKSCAN7.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	1	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	2	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	3	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	4	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	5	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	6	7
ENSP00000338290	zf-C2H2	PF00096.26	1.7e-35	7	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	1	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	2	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	3	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	4	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	5	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	6	7
ENSP00000366250	zf-C2H2	PF00096.26	1.7e-35	7	7
ENSP00000338290	zf-met	PF12874.7	3e-07	1	1
ENSP00000366250	zf-met	PF12874.7	3e-07	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000461789	GZF1-204	675	-	-	- (aa)	-	-
ENST00000477239	GZF1-205	390	-	-	- (aa)	-	-
ENST00000377051	GZF1-202	4740	XM_011529321	ENSP00000366250	711 (aa)	XP_011527623	Q9H116
ENST00000338121	GZF1-201	4835	XM_005260800	ENSP00000338290	711 (aa)	XP_005260857	Q9H116
ENST00000424216	GZF1-203	795	-	ENSP00000410009	48 (aa)	-	Q5JXG1

Gene Model

Click here to download ENSG00000125812's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000125812	Body Mass Index	2.2910000E-005	-
ENSG00000125812	Body Weight	5.5950000E-005	-
ENSG00000125812	Body Weight	1.4220000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125812's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125812	GZF1	90	51.163	ENSAPOG00000012930	GZF1	94	48.013	Acanthochromis_polyacanthus
ENSG00000125812	GZF1	100	93.750	ENSAMEG00000009853	GZF1	100	81.704	Ailuropoda_melanoleuca
ENSG00000125812	GZF1	84	48.918	ENSAOCG00000024275	GZF1	93	48.752	Amphiprion_ocellaris
ENSG00000125812	GZF1	86	46.429	ENSAPEG00000017195	GZF1	73	46.603	Amphiprion_percula
ENSG00000125812	GZF1	90	48.837	ENSATEG00000018374	GZF1	88	77.049	Anabas_testudineus
ENSG00000125812	GZF1	100	97.917	ENSANAG00000028240	GZF1	100	95.077	Aotus_nancymaae
ENSG00000125812	GZF1	86	48.031	ENSAMXG00000017178	GZF1	84	47.717	Astyanax_mexicanus
ENSG00000125812	GZF1	100	100.000	ENSCJAG00000000733	GZF1	100	94.796	Callithrix_jacchus
ENSG00000125812	GZF1	100	91.667	ENSCAFG00000005142	GZF1	100	84.669	Canis_familiaris
ENSG00000125812	GZF1	56	90.455	ENSCAFG00020027463	-	100	90.455	Canis_lupus_dingo
ENSG00000125812	GZF1	100	89.583	ENSTSYG00000028054	GZF1	100	83.101	Carlito_syrichta
ENSG00000125812	GZF1	100	85.417	ENSCAPG00000002173	GZF1	100	78.352	Cavia_aperea
ENSG00000125812	GZF1	100	85.417	ENSCPOG00000010790	GZF1	100	78.442	Cavia_porcellus
ENSG00000125812	GZF1	100	100.000	ENSCCAG00000035601	GZF1	100	94.655	Cebus_capucinus
ENSG00000125812	GZF1	100	100.000	ENSCATG00000039279	GZF1	100	97.756	Cercocebus_atys
ENSG00000125812	GZF1	100	85.417	ENSCLAG00000014714	GZF1	100	77.732	Chinchilla_lanigera
ENSG00000125812	GZF1	100	100.000	ENSCSAG00000011054	GZF1	100	97.893	Chlorocebus_sabaeus
ENSG00000125812	GZF1	94	51.572	ENSCPBG00000023418	-	72	54.138	Chrysemys_picta_bellii
ENSG00000125812	GZF1	100	85.417	ENSCPBG00000023415	GZF1	100	76.045	Chrysemys_picta_bellii
ENSG00000125812	GZF1	100	100.000	ENSCANG00000041260	GZF1	100	97.750	Colobus_angolensis_palliatus
ENSG00000125812	GZF1	100	89.583	ENSCGRG00001003944	Gzf1	100	80.309	Cricetulus_griseus_chok1gshd
ENSG00000125812	GZF1	100	89.583	ENSCGRG00000012721	Gzf1	100	80.309	Cricetulus_griseus_crigri
ENSG00000125812	GZF1	80	84.000	ENSDNOG00000014290	GZF1	100	84.000	Dasypus_novemcinctus
ENSG00000125812	GZF1	100	95.833	ENSDORG00000011855	Gzf1	100	86.034	Dipodomys_ordii
ENSG00000125812	GZF1	59	75.465	ENSEBUG00000004858	GZF1	55	75.465	Eptatretus_burgeri
ENSG00000125812	GZF1	56	92.727	ENSECAG00000040045	-	100	92.727	Equus_caballus
ENSG00000125812	GZF1	83	45.636	ENSELUG00000013581	GZF1	86	45.487	Esox_lucius
ENSG00000125812	GZF1	100	93.750	ENSFCAG00000006484	GZF1	100	86.014	Felis_catus
ENSG00000125812	GZF1	100	85.417	ENSFDAG00000019468	GZF1	96	76.765	Fukomys_damarensis
ENSG00000125812	GZF1	90	53.488	ENSFHEG00000020498	GZF1	74	46.497	Fundulus_heteroclitus
ENSG00000125812	GZF1	86	47.106	ENSGMOG00000011017	GZF1	100	47.665	Gadus_morhua
ENSG00000125812	GZF1	100	85.417	ENSGALG00000053640	GZF1	100	76.144	Gallus_gallus
ENSG00000125812	GZF1	90	48.837	ENSGAFG00000008725	GZF1	72	45.257	Gambusia_affinis
ENSG00000125812	GZF1	90	53.488	ENSGACG00000012415	GZF1	99	71.429	Gasterosteus_aculeatus
ENSG00000125812	GZF1	100	100.000	ENSGGOG00000023248	GZF1	100	99.157	Gorilla_gorilla
ENSG00000125812	GZF1	100	87.500	ENSHGLG00000008891	GZF1	100	77.279	Heterocephalus_glaber_female
ENSG00000125812	GZF1	100	87.500	ENSHGLG00100015117	GZF1	100	77.279	Heterocephalus_glaber_male
ENSG00000125812	GZF1	99	42.659	ENSHCOG00000004326	GZF1	75	54.412	Hippocampus_comes
ENSG00000125812	GZF1	100	95.833	ENSSTOG00000009820	GZF1	100	86.676	Ictidomys_tridecemlineatus
ENSG00000125812	GZF1	100	97.917	ENSJJAG00000008172	Gzf1	100	84.476	Jaculus_jaculus
ENSG00000125812	GZF1	82	71.579	ENSKMAG00000001453	-	59	71.579	Kryptolebias_marmoratus
ENSG00000125812	GZF1	85	53.659	ENSLBEG00000025803	-	74	47.812	Labrus_bergylta
ENSG00000125812	GZF1	100	91.667	ENSLAFG00000002458	GZF1	100	87.342	Loxodonta_africana
ENSG00000125812	GZF1	100	100.000	ENSMFAG00000042408	GZF1	100	97.756	Macaca_fascicularis
ENSG00000125812	GZF1	100	100.000	ENSMMUG00000022387	GZF1	100	97.756	Macaca_mulatta
ENSG00000125812	GZF1	100	100.000	ENSMNEG00000033117	GZF1	100	97.893	Macaca_nemestrina
ENSG00000125812	GZF1	100	100.000	ENSMLEG00000036831	GZF1	100	97.893	Mandrillus_leucophaeus
ENSG00000125812	GZF1	96	42.978	ENSMAMG00000011931	-	64	59.569	Mastacembelus_armatus
ENSG00000125812	GZF1	100	89.583	ENSMAUG00000019656	Gzf1	100	82.185	Mesocricetus_auratus
ENSG00000125812	GZF1	100	95.833	ENSMICG00000046070	GZF1	100	89.888	Microcebus_murinus
ENSG00000125812	GZF1	100	89.583	ENSMOCG00000017816	Gzf1	100	79.102	Microtus_ochrogaster
ENSG00000125812	GZF1	90	48.837	ENSMMOG00000004395	-	75	48.450	Mola_mola
ENSG00000125812	GZF1	100	87.500	ENSMODG00000006238	GZF1	100	81.923	Monodelphis_domestica
ENSG00000125812	GZF1	100	91.667	MGP_CAROLIEiJ_G0024409	Gzf1	100	82.841	Mus_caroli
ENSG00000125812	GZF1	100	87.500	ENSMUSG00000027439	Gzf1	100	82.022	Mus_musculus
ENSG00000125812	GZF1	100	91.667	MGP_PahariEiJ_G0025852	Gzf1	100	82.048	Mus_pahari
ENSG00000125812	GZF1	100	87.500	MGP_SPRETEiJ_G0025327	Gzf1	100	82.022	Mus_spretus
ENSG00000125812	GZF1	100	93.750	ENSMPUG00000001160	GZF1	89	84.615	Mustela_putorius_furo
ENSG00000125812	GZF1	100	91.667	ENSMLUG00000002194	GZF1	100	82.286	Myotis_lucifugus
ENSG00000125812	GZF1	100	95.833	ENSNGAG00000024012	Gzf1	100	85.955	Nannospalax_galili
ENSG00000125812	GZF1	100	47.917	ENSNBRG00000019987	GZF1	98	44.463	Neolamprologus_brichardi
ENSG00000125812	GZF1	100	97.750	ENSNLEG00000011565	GZF1	100	97.750	Nomascus_leucogenys
ENSG00000125812	GZF1	100	87.500	ENSOPRG00000004697	GZF1	100	79.391	Ochotona_princeps
ENSG00000125812	GZF1	100	81.250	ENSODEG00000013020	GZF1	100	74.298	Octodon_degus
ENSG00000125812	GZF1	61	70.000	ENSONIG00000000989	GZF1	73	70.000	Oreochromis_niloticus
ENSG00000125812	GZF1	50	42.322	ENSOANG00000022376	-	54	48.223	Ornithorhynchus_anatinus
ENSG00000125812	GZF1	100	95.833	ENSOCUG00000025214	GZF1	100	81.907	Oryctolagus_cuniculus
ENSG00000125812	GZF1	100	93.750	ENSOGAG00000028389	GZF1	100	87.060	Otolemur_garnettii
ENSG00000125812	GZF1	100	100.000	ENSPPAG00000028487	GZF1	100	99.156	Pan_paniscus
ENSG00000125812	GZF1	100	93.750	ENSPPRG00000010040	GZF1	100	86.014	Panthera_pardus
ENSG00000125812	GZF1	100	93.750	ENSPTIG00000019328	GZF1	100	86.154	Panthera_tigris_altaica
ENSG00000125812	GZF1	100	100.000	ENSPTRG00000013320	GZF1	100	98.734	Pan_troglodytes
ENSG00000125812	GZF1	100	100.000	ENSPANG00000017419	GZF1	100	97.753	Papio_anubis
ENSG00000125812	GZF1	86	51.572	ENSPKIG00000003781	GZF1	77	49.381	Paramormyrops_kingsleyae
ENSG00000125812	GZF1	98	42.553	ENSPSIG00000014208	-	72	54.483	Pelodiscus_sinensis
ENSG00000125812	GZF1	100	83.333	ENSPSIG00000014455	GZF1	100	76.050	Pelodiscus_sinensis
ENSG00000125812	GZF1	90	48.837	ENSPMGG00000003778	-	67	51.737	Periophthalmus_magnuspinnatus
ENSG00000125812	GZF1	100	89.583	ENSPEMG00000011285	Gzf1	100	81.320	Peromyscus_maniculatus_bairdii
ENSG00000125812	GZF1	100	85.417	ENSPCIG00000013803	GZF1	100	78.134	Phascolarctos_cinereus
ENSG00000125812	GZF1	99	41.984	ENSPFOG00000002393	GZF1	100	47.334	Poecilia_formosa
ENSG00000125812	GZF1	90	46.512	ENSPLAG00000005232	GZF1	93	46.069	Poecilia_latipinna
ENSG00000125812	GZF1	90	46.512	ENSPMEG00000020017	-	82	37.154	Poecilia_mexicana
ENSG00000125812	GZF1	90	48.837	ENSPREG00000016398	GZF1	83	39.441	Poecilia_reticulata
ENSG00000125812	GZF1	100	100.000	ENSPPYG00000010766	GZF1	100	97.566	Pongo_abelii
ENSG00000125812	GZF1	82	84.957	ENSPCAG00000007544	GZF1	100	84.444	Procavia_capensis
ENSG00000125812	GZF1	100	95.833	ENSPCOG00000024180	GZF1	100	91.421	Propithecus_coquereli
ENSG00000125812	GZF1	100	91.667	ENSPVAG00000014056	GZF1	100	86.357	Pteropus_vampyrus
ENSG00000125812	GZF1	100	89.583	ENSRNOG00000004735	Gzf1	100	82.188	Rattus_norvegicus
ENSG00000125812	GZF1	100	100.000	ENSRBIG00000028715	GZF1	100	97.063	Rhinopithecus_bieti
ENSG00000125812	GZF1	100	100.000	ENSRROG00000030533	GZF1	100	97.335	Rhinopithecus_roxellana
ENSG00000125812	GZF1	100	100.000	ENSSBOG00000018893	GZF1	100	94.655	Saimiri_boliviensis_boliviensis
ENSG00000125812	GZF1	100	85.417	ENSSHAG00000009367	GZF1	100	77.964	Sarcophilus_harrisii
ENSG00000125812	GZF1	100	43.750	ENSSFOG00015008631	gzf1	78	48.281	Scleropages_formosus
ENSG00000125812	GZF1	100	45.833	ENSSDUG00000008186	GZF1	74	46.970	Seriola_dumerili
ENSG00000125812	GZF1	100	45.833	ENSSLDG00000002382	GZF1	74	46.466	Seriola_lalandi_dorsalis
ENSG00000125812	GZF1	100	91.667	ENSSARG00000010285	GZF1	79	89.583	Sorex_araneus
ENSG00000125812	GZF1	100	83.333	ENSSPUG00000004147	GZF1	100	70.233	Sphenodon_punctatus
ENSG00000125812	GZF1	90	51.163	ENSSPAG00000011759	GZF1	75	46.390	Stegastes_partitus
ENSG00000125812	GZF1	85	79.608	ENSSSCG00000007117	GZF1	100	79.282	Sus_scrofa
ENSG00000125812	GZF1	60	68.647	ENSTRUG00000006128	-	56	60.556	Takifugu_rubripes
ENSG00000125812	GZF1	86	46.926	ENSTNIG00000010722	GZF1	100	46.166	Tetraodon_nigroviridis
ENSG00000125812	GZF1	100	91.667	ENSTTRG00000011345	GZF1	100	81.224	Tursiops_truncatus
ENSG00000125812	GZF1	56	92.727	ENSUAMG00000021858	-	100	92.727	Ursus_americanus
ENSG00000125812	GZF1	100	93.750	ENSUMAG00000004065	GZF1	100	85.455	Ursus_maritimus
ENSG00000125812	GZF1	100	91.667	ENSVVUG00000012086	GZF1	100	84.810	Vulpes_vulpes
ENSG00000125812	GZF1	100	68.750	ENSXETG00000004510	gzf1	99	59.916	Xenopus_tropicalis
ENSG00000125812	GZF1	98	42.177	ENSXMAG00000023249	GZF1	85	42.917	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	16049025.	IDA	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	16049025.	IMP	Process
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	16049025.	IDA	Function
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	16049025.	IMP	Function
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	16049025.	IDA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	16049025.	IDA	Function
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	16049025.	IMP	Function
GO:0001658	branching involved in ureteric bud morphogenesis	-	IEA	Process
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	IEA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0043565	sequence-specific DNA binding	16049025.	IDA	Function
GO:0045892	negative regulation of transcription, DNA-templated	16049025.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function