EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000125998 (Gene tree)
Gene ID: 128876
Gene Symbol: FAM83C
Alias: dJ614O4.7|C20orf128
Full Name: family with sequence similarity 83 member C
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 6,692 bases
Position: chr20:35,285,731-35,292,422
Accession: 16121
RBP type: canonical RBP
Summary: This gene encodes a member of the family with sequence similarity 83 protein family. The encoded protein may be involved in regulating MAPK signaling in cancer cells. [provided by RefSeq, Mar 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000363529	FAM83	PF07894.12	1.5e-101	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374408	FAM83C-201	3145	-	ENSP00000363529	747 (aa)	-	Q9BQN1

Gene Model

Click here to download ENSG00000125998's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000125998's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000125998	FAM83C	100	83.467	ENSAMEG00000009786	FAM83C	100	83.467	Ailuropoda_melanoleuca
ENSG00000125998	FAM83C	58	68.750	ENSAPEG00000023028	fam83c	81	68.750	Amphiprion_percula
ENSG00000125998	FAM83C	52	62.951	ENSAPLG00000007684	FAM83C	76	62.951	Anas_platyrhynchos
ENSG00000125998	FAM83C	100	92.000	ENSANAG00000024148	FAM83C	100	92.133	Aotus_nancymaae
ENSG00000125998	FAM83C	98	79.620	ENSBTAG00000006278	FAM83C	100	79.620	Bos_taurus
ENSG00000125998	FAM83C	100	90.267	ENSCJAG00000017842	FAM83C	100	90.267	Callithrix_jacchus
ENSG00000125998	FAM83C	100	81.660	ENSCAFG00000008011	FAM83C	100	81.660	Canis_familiaris
ENSG00000125998	FAM83C	100	81.333	ENSCAFG00020005360	FAM83C	98	81.333	Canis_lupus_dingo
ENSG00000125998	FAM83C	98	79.348	ENSCHIG00000020912	FAM83C	100	79.348	Capra_hircus
ENSG00000125998	FAM83C	100	84.267	ENSTSYG00000036093	FAM83C	100	84.267	Carlito_syrichta
ENSG00000125998	FAM83C	99	74.899	ENSCAPG00000016579	FAM83C	96	74.899	Cavia_aperea
ENSG00000125998	FAM83C	99	77.584	ENSCPOG00000027379	FAM83C	96	77.584	Cavia_porcellus
ENSG00000125998	FAM83C	100	90.559	ENSCCAG00000025013	FAM83C	100	90.559	Cebus_capucinus
ENSG00000125998	FAM83C	100	93.440	ENSCATG00000045115	FAM83C	100	93.440	Cercocebus_atys
ENSG00000125998	FAM83C	98	80.435	ENSCLAG00000016840	FAM83C	100	80.267	Chinchilla_lanigera
ENSG00000125998	FAM83C	100	93.307	ENSCSAG00000010439	FAM83C	100	93.307	Chlorocebus_sabaeus
ENSG00000125998	FAM83C	62	58.750	ENSCPBG00000002041	FAM83C	67	58.750	Chrysemys_picta_bellii
ENSG00000125998	FAM83C	100	92.771	ENSCANG00000039615	FAM83C	100	92.771	Colobus_angolensis_palliatus
ENSG00000125998	FAM83C	99	79.459	ENSCGRG00001009663	Fam83c	96	79.459	Cricetulus_griseus_chok1gshd
ENSG00000125998	FAM83C	99	79.459	ENSCGRG00000017631	Fam83c	96	79.459	Cricetulus_griseus_crigri
ENSG00000125998	FAM83C	99	80.541	ENSDNOG00000034661	FAM83C	100	80.106	Dasypus_novemcinctus
ENSG00000125998	FAM83C	99	79.702	ENSDORG00000001424	Fam83c	96	79.702	Dipodomys_ordii
ENSG00000125998	FAM83C	54	87.961	ENSETEG00000000068	-	56	86.842	Echinops_telfairi
ENSG00000125998	FAM83C	99	83.762	ENSEASG00005005839	FAM83C	97	83.897	Equus_asinus_asinus
ENSG00000125998	FAM83C	99	83.762	ENSECAG00000010974	FAM83C	97	83.897	Equus_caballus
ENSG00000125998	FAM83C	100	83.067	ENSFCAG00000006431	FAM83C	100	83.200	Felis_catus
ENSG00000125998	FAM83C	98	78.997	ENSFDAG00000020451	FAM83C	98	79.521	Fukomys_damarensis
ENSG00000125998	FAM83C	59	56.111	ENSGALG00000031906	FAM83C	64	61.184	Gallus_gallus
ENSG00000125998	FAM83C	54	51.044	ENSGAGG00000011761	FAM83C	62	62.542	Gopherus_agassizii
ENSG00000125998	FAM83C	100	97.724	ENSGGOG00000012107	FAM83C	100	97.724	Gorilla_gorilla
ENSG00000125998	FAM83C	100	79.920	ENSHGLG00000006814	FAM83C	96	79.920	Heterocephalus_glaber_female
ENSG00000125998	FAM83C	100	78.856	ENSHGLG00100018815	FAM83C	96	78.856	Heterocephalus_glaber_male
ENSG00000125998	FAM83C	52	53.271	ENSHCOG00000014079	fam83c	59	53.271	Hippocampus_comes
ENSG00000125998	FAM83C	100	81.333	ENSSTOG00000019705	FAM83C	100	81.600	Ictidomys_tridecemlineatus
ENSG00000125998	FAM83C	99	79.054	ENSJJAG00000013689	Fam83c	96	79.324	Jaculus_jaculus
ENSG00000125998	FAM83C	100	80.400	ENSLAFG00000029152	FAM83C	100	80.533	Loxodonta_africana
ENSG00000125998	FAM83C	100	93.708	ENSMFAG00000038878	FAM83C	100	93.708	Macaca_fascicularis
ENSG00000125998	FAM83C	100	93.708	ENSMMUG00000018210	FAM83C	100	93.708	Macaca_mulatta
ENSG00000125998	FAM83C	100	93.440	ENSMNEG00000028152	FAM83C	100	93.440	Macaca_nemestrina
ENSG00000125998	FAM83C	100	93.574	ENSMLEG00000004620	FAM83C	100	93.574	Mandrillus_leucophaeus
ENSG00000125998	FAM83C	58	53.448	ENSMGAG00000001956	FAM83C	69	61.056	Meleagris_gallopavo
ENSG00000125998	FAM83C	100	79.200	ENSMAUG00000011286	Fam83c	99	79.200	Mesocricetus_auratus
ENSG00000125998	FAM83C	100	84.000	ENSMICG00000013976	FAM83C	100	84.133	Microcebus_murinus
ENSG00000125998	FAM83C	99	79.595	ENSMOCG00000016691	Fam83c	99	79.595	Microtus_ochrogaster
ENSG00000125998	FAM83C	100	56.863	ENSMODG00000019691	FAM83C	100	57.441	Monodelphis_domestica
ENSG00000125998	FAM83C	99	79.189	MGP_CAROLIEiJ_G0024540	-	95	79.189	Mus_caroli
ENSG00000125998	FAM83C	99	78.784	ENSMUSG00000074647	Fam83c	95	78.784	Mus_musculus
ENSG00000125998	FAM83C	99	79.459	MGP_PahariEiJ_G0025985	Fam83c	95	79.459	Mus_pahari
ENSG00000125998	FAM83C	99	78.378	MGP_SPRETEiJ_G0025462	Fam83c	95	78.378	Mus_spretus
ENSG00000125998	FAM83C	100	84.267	ENSMPUG00000017801	FAM83C	100	84.533	Mustela_putorius_furo
ENSG00000125998	FAM83C	99	82.679	ENSMLUG00000004473	FAM83C	99	89.815	Myotis_lucifugus
ENSG00000125998	FAM83C	91	81.093	ENSNGAG00000010632	Fam83c	95	81.093	Nannospalax_galili
ENSG00000125998	FAM83C	99	94.973	ENSNLEG00000010219	FAM83C	100	94.645	Nomascus_leucogenys
ENSG00000125998	FAM83C	96	58.798	ENSMEUG00000007181	FAM83C	99	55.751	Notamacropus_eugenii
ENSG00000125998	FAM83C	99	79.491	ENSOPRG00000005474	FAM83C	99	79.491	Ochotona_princeps
ENSG00000125998	FAM83C	99	81.074	ENSOCUG00000000488	FAM83C	99	81.074	Oryctolagus_cuniculus
ENSG00000125998	FAM83C	100	83.622	ENSOGAG00000001833	FAM83C	100	83.755	Otolemur_garnettii
ENSG00000125998	FAM83C	99	78.735	ENSOARG00000012242	FAM83C	98	78.735	Ovis_aries
ENSG00000125998	FAM83C	100	99.331	ENSPPAG00000037890	FAM83C	100	99.331	Pan_paniscus
ENSG00000125998	FAM83C	100	82.933	ENSPPRG00000006244	FAM83C	100	83.067	Panthera_pardus
ENSG00000125998	FAM83C	100	78.933	ENSPTIG00000020766	FAM83C	100	79.067	Panthera_tigris_altaica
ENSG00000125998	FAM83C	100	99.063	ENSPTRG00000013437	FAM83C	100	99.063	Pan_troglodytes
ENSG00000125998	FAM83C	100	93.307	ENSPANG00000009736	FAM83C	100	93.307	Papio_anubis
ENSG00000125998	FAM83C	99	80.027	ENSPEMG00000021622	Fam83c	97	80.027	Peromyscus_maniculatus_bairdii
ENSG00000125998	FAM83C	100	55.172	ENSPCIG00000027973	FAM83C	100	54.765	Phascolarctos_cinereus
ENSG00000125998	FAM83C	100	96.252	ENSPPYG00000010950	FAM83C	100	96.252	Pongo_abelii
ENSG00000125998	FAM83C	99	79.217	ENSPCAG00000003794	FAM83C	100	79.521	Procavia_capensis
ENSG00000125998	FAM83C	99	86.043	ENSPCOG00000022524	FAM83C	100	85.981	Propithecus_coquereli
ENSG00000125998	FAM83C	100	79.333	ENSPVAG00000010434	FAM83C	100	79.333	Pteropus_vampyrus
ENSG00000125998	FAM83C	99	78.919	ENSRNOG00000046772	Fam83c	95	78.919	Rattus_norvegicus
ENSG00000125998	FAM83C	100	93.574	ENSRBIG00000040153	FAM83C	100	93.574	Rhinopithecus_bieti
ENSG00000125998	FAM83C	100	93.574	ENSRROG00000040897	FAM83C	100	93.574	Rhinopithecus_roxellana
ENSG00000125998	FAM83C	100	91.733	ENSSBOG00000025721	FAM83C	100	91.867	Saimiri_boliviensis_boliviensis
ENSG00000125998	FAM83C	99	56.596	ENSSHAG00000018354	FAM83C	100	55.832	Sarcophilus_harrisii
ENSG00000125998	FAM83C	58	65.625	ENSSDUG00000017583	fam83c	80	65.625	Seriola_dumerili
ENSG00000125998	FAM83C	85	92.208	ENSSARG00000000723	FAM83C	87	88.889	Sorex_araneus
ENSG00000125998	FAM83C	58	62.171	ENSSPUG00000012470	FAM83C	64	62.171	Sphenodon_punctatus
ENSG00000125998	FAM83C	98	81.522	ENSSSCG00000028858	FAM83C	100	81.522	Sus_scrofa
ENSG00000125998	FAM83C	87	86.550	ENSTBEG00000008768	FAM83C	87	85.380	Tupaia_belangeri
ENSG00000125998	FAM83C	91	76.385	ENSTTRG00000017014	FAM83C	99	76.385	Tursiops_truncatus
ENSG00000125998	FAM83C	100	83.200	ENSUAMG00000007959	FAM83C	98	83.200	Ursus_americanus
ENSG00000125998	FAM83C	100	83.467	ENSUMAG00000005095	FAM83C	95	83.467	Ursus_maritimus
ENSG00000125998	FAM83C	100	81.600	ENSVVUG00000003966	FAM83C	98	81.600	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0019901	protein kinase binding	24736947.	IPI	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr20	35286615	Missense_Mutation	novel	L722M	0.11
BLCA	chr20	35287176	Missense_Mutation	rs199571076	R535W	0.55
BLCA	chr20	35292029	Silent	rs758914035	S92S	0.11
BLCA	chr20	35286845	Missense_Mutation	rs538680638	R645H	0.18
BLCA	chr20	35286487	3'UTR	novel		0.29
BLCA	chr20	35286855	Missense_Mutation	rs761122449	G642S	0.37
BLCA	chr20	35287583	Nonsense_Mutation	NA	S399*	0.09
BLCA	chr20	35286637	Silent	NA	V714V	0.26
BLCA	chr20	35292028	Missense_Mutation	rs753289930	E93K	0.2	FAM83
BLCA	chr20	35292030	Missense_Mutation	NA	S92N	0.16	FAM83
BLCA	chr20	35286903	Missense_Mutation	rs141772980	R626W	0.48
BRCA	chr20	35288496	Silent	NA	L257L	0.23
BRCA	chr20	35287815	Silent	NA	L322L	0.35
BRCA	chr20	35287365	Missense_Mutation	NA	G472R	0.1
BRCA	chr20	35288800	Silent	novel	E224E	0.25
BRCA	chr20	35287423	Silent	NA	L452L	0.2
BRCA	chr20	35287069	Missense_Mutation	novel	L570F	0.1
BRCA	chr20	35287340	Missense_Mutation	rs769630479	R480Q	0.36
CESC	chr20	35287686	Missense_Mutation	rs373959129	L365V	0.16
CESC	chr20	35287726	Missense_Mutation	novel	I351M	0.27
CESC	chr20	35287435	Silent	rs772792580	R448R	0.37
CESC	chr20	35287446	Silent	NA	L445L	0.34
COAD	chr20	35287593	Missense_Mutation	rs753833214	R396C	0.34
COAD	chr20	35292050	Silent	novel	V85V	0.2
COAD	chr20	35287539	Missense_Mutation	novel	L414V	0.32
COAD	chr20	35291850	Missense_Mutation	novel	R152M	0.1	FAM83
COAD	chr20	35286881	Missense_Mutation	novel	S633N	0.39
COAD	chr20	35287451	Missense_Mutation	NA	S443L	0.48
COAD	chr20	35291811	Missense_Mutation	novel	L165P	0.07	FAM83
COAD	chr20	35287578	Missense_Mutation	NA	P401S	0.12
COAD	chr20	35286695	Missense_Mutation	NA	G695E	0.07
COAD	chr20	35287715	Missense_Mutation	rs776810089	P355L	0.14
COAD	chr20	35292047	Silent	rs781331537	R86R	0.29
COAD	chr20	35287342	Silent	NA	L479L	0.37
COAD	chr20	35291818	Missense_Mutation	rs755472776	R163C	0.34	FAM83
COAD	chr20	35286765	Missense_Mutation	rs138265873	R672W	0.12
COAD	chr20	35287125	Missense_Mutation	rs748263316	D552N	0.76
COAD	chr20	35288531	Missense_Mutation	rs777921694	R246C	0.16	FAM83
ESCA	chr20	35292102	Missense_Mutation	rs147988294	R68Q	0.1	FAM83
ESCA	chr20	35287690	Silent	novel	L363L	0.17
ESCA	chr20	35287457	Missense_Mutation	novel	V441G	0.39
GBM	chr20	35286411	3'UTR	novel		0.43
GBM	chr20	35286798	Missense_Mutation	rs202028958	R661C	0.49
GBM	chr20	35287079	Missense_Mutation	NA	A567V	0.52
GBM	chr20	35288534	Missense_Mutation	rs138765880	R245C	0.06	FAM83
HNSC	chr20	35288477	Missense_Mutation	novel	V264L	0.12	FAM83
HNSC	chr20	35287389	Missense_Mutation	rs376562401	R464W	0.22
HNSC	chr20	35292178	Missense_Mutation	novel	E43K	0.21	FAM83
HNSC	chr20	35288520	Silent	novel	G249G	0.04
HNSC	chr20	35287839	Missense_Mutation	novel	E314K	0.38
HNSC	chr20	35291817	Missense_Mutation	rs749884709	R163H	0.14	FAM83
HNSC	chr20	35287784	Missense_Mutation	novel	R332K	0.42
HNSC	chr20	35287700	Missense_Mutation	NA	S360F	0.4
HNSC	chr20	35286801	Missense_Mutation	novel	A660T	0.21
KICH	chr20	35286623	Missense_Mutation	rs747968163	R719Q	0.53
KIRC	chr20	35287802	Missense_Mutation	NA	P326L	0.5
KIRC	chr20	35287776	Missense_Mutation	NA	V335I	0.35
KIRC	chr20	35287294	In_Frame_Del	rs756547646	K495del	0.25
KIRP	chr20	35286779	Missense_Mutation	NA	S667C	0.43
LGG	chr20	35287322	Missense_Mutation	novel	G486D	0.44
LIHC	chr20	35287437	Missense_Mutation	rs375816362	R448C	0.41
LIHC	chr20	35286765	Missense_Mutation	rs138265873	R672W	0.3
LUAD	chr20	35292052	Missense_Mutation	NA	V85L	0.27	FAM83
LUAD	chr20	35291873	Silent	novel	T144T	0.3
LUAD	chr20	35287608	Missense_Mutation	novel	Q391E	0.14
LUAD	chr20	35286517	3'UTR	novel		0.5
LUAD	chr20	35287345	Silent	NA	P478P	0.26
LUAD	chr20	35288879	Missense_Mutation	novel	V198D	0.48	FAM83
LUAD	chr20	35287139	Missense_Mutation	NA	S547Y	0.42
LUAD	chr20	35286852	Missense_Mutation	novel	P643T	0.18
LUAD	chr20	35287191	Frame_Shift_Ins	novel	*N530Qfs40**	0.45
LUAD	chr20	35287100	Missense_Mutation	novel	R560Q	0.31
LUAD	chr20	35287776	Missense_Mutation	NA	V335F	0.29
LUAD	chr20	35287303	Silent	novel	V492V	0.06
LUAD	chr20	35288869	Nonsense_Mutation	NA	Y201*	0.31	FAM83
LUAD	chr20	35286623	Missense_Mutation	rs747968163	R719Q	0.08
LUAD	chr20	35286733	Silent	NA	L682L	0.07
LUAD	chr20	35287373	Missense_Mutation	novel	G469A	0.28
LUAD	chr20	35287194	Missense_Mutation	novel	P529T	0.22
LUAD	chr20	35287032	Missense_Mutation	novel	R583W	0.25
LUAD	chr20	35287120	Missense_Mutation	novel	S553R	0.44
LUAD	chr20	35287517	Missense_Mutation	novel	P421Q	0.08
LUAD	chr20	35288959	Splice_Site	NA	X172_splice	0.35
LUAD	chr20	35287826	Missense_Mutation	NA	S318C	0.23
LUAD	chr20	35288473	Missense_Mutation	rs769453860	A265V	0.32	FAM83
LUAD	chr20	35287157	Missense_Mutation	novel	P541L	0.39
LUAD	chr20	35286954	Missense_Mutation	NA	P609T	0.35
LUSC	chr20	35287709	Missense_Mutation	NA	M357K	0.33
LUSC	chr20	35288905	Silent	NA	L189L	0.27
LUSC	chr20	35286876	Missense_Mutation	novel	L635M	0.11
LUSC	chr20	35288510	Missense_Mutation	NA	E253K	0.19	FAM83
LUSC	chr20	35287156	Silent	novel	P541P	0.16
LUSC	chr20	35286739	Silent	NA	L680L	0.23
LUSC	chr20	35287278	Missense_Mutation	novel	P501S	0.35
LUSC	chr20	35287798	Silent	novel	V327V	0.32
LUSC	chr20	35287235	Missense_Mutation	NA	P515L	0.37
LUSC	chr20	35292192	Missense_Mutation	novel	V38E	0.21	FAM83
LUSC	chr20	35287604	Missense_Mutation	NA	P392H	0.73
LUSC	chr20	35287682	Missense_Mutation	novel	P366L	0.35
LUSC	chr20	35287067	Missense_Mutation	rs766057483	G571D	0.2
LUSC	chr20	35287293	Nonsense_Mutation	novel	E496*	0.34
LUSC	chr20	35287657	Silent	novel	T374T	0.33
LUSC	chr20	35286727	Silent	novel	T684T	0.26
OV	chr20	35291937	Frame_Shift_Ins	novel	*I123Nfs9**	0.06	FAM83
OV	chr20	35286757	Silent	NA	T674T	0.13
OV	chr20	35286640	Silent	NA	L713L	0.31
PAAD	chr20	35286647	Missense_Mutation	novel	S711I	0.19
PAAD	chr20	35286446	3'UTR	novel		0.36
PRAD	chr20	35287431	Missense_Mutation	rs369109150	R450W	0.07
PRAD	chr20	35287472	Missense_Mutation	novel	P436H	0.31
PRAD	chr20	35287436	Missense_Mutation	rs760221525	R448H	0.23
PRAD	chr20	35286903	Missense_Mutation	rs141772980	R626W	0.45
PRAD	chr20	35287559	Missense_Mutation	novel	P407H	0.5
READ	chr20	35287227	Nonsense_Mutation	rs752621565	R518*	0.55
SARC	chr20	35287311	Missense_Mutation	novel	E490K	0.25
SARC	chr20	35292141	Missense_Mutation	rs776231191	R55Q	0.09	FAM83
SKCM	chr20	35291828	Silent	NA	K159K	0.35
SKCM	chr20	35287560	Missense_Mutation	NA	P407S	0.38
SKCM	chr20	35286814	Silent	rs756956339	P655P	0.32
SKCM	chr20	35287108	Silent	rs367735746	L557L	0.49
SKCM	chr20	35287339	Silent	novel	R480R	0.38
SKCM	chr20	35288502	Missense_Mutation	NA	F255L	0.19	FAM83
SKCM	chr20	35287148	Missense_Mutation	novel	R544K	0.52
SKCM	chr20	35287593	Missense_Mutation	rs753833214	R396C	0.15
SKCM	chr20	35286938	Missense_Mutation	NA	S614F	0.4
SKCM	chr20	35286697	Silent	rs753918972	Q694Q	0.34
SKCM	chr20	35287433	Missense_Mutation	novel	S449F	0.34
SKCM	chr20	35291953	Missense_Mutation	novel	P118S	0.31	FAM83
SKCM	chr20	35287643	Missense_Mutation	rs765267690	S379L	0.26
SKCM	chr20	35291864	Silent	NA	V147V	0.29
SKCM	chr20	35286690	Missense_Mutation	NA	E697K	0.31
SKCM	chr20	35286456	3'UTR	novel		0.42
SKCM	chr20	35287559	Frame_Shift_Del	novel	*P406Wfs4**	0.19
SKCM	chr20	35287426	Silent	NA	P451P	0.31
SKCM	chr20	35287108	Silent	rs367735746	L557L	0.35
SKCM	chr20	35286683	Missense_Mutation	NA	G699E	0.16
SKCM	chr20	35287395	Silent	novel	L462L	0.32
SKCM	chr20	35291831	Silent	NA	I158I	0.25
SKCM	chr20	35287423	Silent	NA	L452L	0.19
SKCM	chr20	35291907	Missense_Mutation	NA	P133L	0.24	FAM83
SKCM	chr20	35292166	Silent	NA	L47L	0.27
SKCM	chr20	35291813	Silent	novel	F164F	0.29
SKCM	chr20	35287645	Silent	NA	S378S	0.18
SKCM	chr20	35292198	Missense_Mutation	rs549811858	P36L	0.21	FAM83
SKCM	chr20	35287423	Silent	NA	L452L	0.46
SKCM	chr20	35291872	Nonsense_Mutation	NA	Q145*	0.16	FAM83
SKCM	chr20	35286529	3'UTR	novel		0.38
SKCM	chr20	35287451	Missense_Mutation	NA	S443L	0.15
SKCM	chr20	35287055	Missense_Mutation	novel	P575L	0.14
SKCM	chr20	35287056	Missense_Mutation	novel	P575S	0.14
SKCM	chr20	35287410	Missense_Mutation	NA	R457W	0.31
SKCM	chr20	35288510	Missense_Mutation	NA	E253K	0.38	FAM83
SKCM	chr20	35287554	Missense_Mutation	NA	L409F	0.17
SKCM	chr20	35286707	Missense_Mutation	NA	G691E	0.14
SKCM	chr20	35287354	Silent	novel	E475E	0.52
SKCM	chr20	35288563	Missense_Mutation	NA	C235Y	0.21	FAM83
SKCM	chr20	35286935	Missense_Mutation	rs775523670	S615L	0.38
SKCM	chr20	35291792	Splice_Region	rs776690764	T171T	0.28
SKCM	chr20	35286952	Silent	NA	P609P	0.24
SKCM	chr20	35287217	Missense_Mutation	NA	G521E	0.21
SKCM	chr20	35287502	Missense_Mutation	novel	S426F	0.4
SKCM	chr20	35292173	Silent	rs770705150	A44A	0.63
SKCM	chr20	35287384	Silent	novel	F465F	0.23
SKCM	chr20	35287344	Silent	novel	L479L	0.61
SKCM	chr20	35287774	Silent	novel	V335V	0.26
SKCM	chr20	35286972	Missense_Mutation	NA	A603T	0.29
STAD	chr20	35287334	Missense_Mutation	rs781027964	R482Q	0.33
STAD	chr20	35288959	Splice_Site	NA	X172_splice	0.27
STAD	chr20	35292066	Missense_Mutation	NA	Y80C	0.1	FAM83
STAD	chr20	35286842	Missense_Mutation	NA	G646V	0.18
STAD	chr20	35292169	Missense_Mutation	rs777525868	R46W	0.17	FAM83
STAD	chr20	35291928	Frame_Shift_Del	novel	*P126Qfs51**	0.13	FAM83
STAD	chr20	35286834	Missense_Mutation	NA	P649S	0.4
STAD	chr20	35288552	Missense_Mutation	rs373419404	Y239H	0.18	FAM83
THCA	chr20	35286443	3'UTR	novel		0.5
UCEC	chr20	35291837	Missense_Mutation	rs772399074	K156N	0.28	FAM83
UCEC	chr20	35287389	Missense_Mutation	rs376562401	R464W	0.34
UCEC	chr20	35286624	Missense_Mutation	rs77803666	R719W	0.36
UCEC	chr20	35286891	Missense_Mutation	novel	L630M	0.32
UCEC	chr20	35287422	Missense_Mutation	novel	L453I	0.32
UCEC	chr20	35287714	Silent	NA	P355P	0.36
UCEC	chr20	35292004	Missense_Mutation	rs768645856	G101R	0.3	FAM83
UCEC	chr20	35288855	Missense_Mutation	NA	Q206R	0.55	FAM83
UCEC	chr20	35287036	Missense_Mutation	novel	E581D	0.22
UCEC	chr20	35286523	3'UTR	novel		0.16
UCEC	chr20	35292048	Missense_Mutation	novel	R86H	0.43	FAM83
UCEC	chr20	35287727	Missense_Mutation	novel	I351T	0.05
UCEC	chr20	35287552	Silent	NA	L409L	0.53
UCEC	chr20	35287819	Silent	NA	R320R	0.43
UCEC	chr20	35288923	Missense_Mutation	novel	M183I	0.6	FAM83
UCEC	chr20	35287458	Missense_Mutation	novel	V441L	0.35
UCEC	chr20	35287916	Missense_Mutation	rs193920940	R288H	0.33	FAM83
UCEC	chr20	35286547	Silent	rs747879494	R744R	0.51
UCEC	chr20	35287831	Silent	rs757676100	P316P	0.24
UCEC	chr20	35287592	Missense_Mutation	NA	R396H	0.13
UCEC	chr20	35291817	Missense_Mutation	rs749884709	R163H	0.41	FAM83
UCEC	chr20	35287916	Missense_Mutation	rs193920940	R288H	0.09	FAM83
UCEC	chr20	35291818	Missense_Mutation	rs755472776	R163C	0.44	FAM83
UCEC	chr20	35286814	Silent	rs756956339	P655P	0.43
UCEC	chr20	35292041	Silent	novel	G88G	0.12
UCEC	chr20	35287339	Silent	novel	R480R	0.21
UCEC	chr20	35287868	Missense_Mutation	novel	S304L	0.18	FAM83
UCEC	chr20	35287518	Missense_Mutation	novel	P421S	0.35
UCEC	chr20	35287037	Missense_Mutation	novel	E581V	0.36
UCEC	chr20	35287593	Missense_Mutation	rs753833214	R396C	0.31
UCEC	chr20	35287535	Missense_Mutation	novel	G415D	0.11
UCEC	chr20	35287867	Silent	rs35692367	S304S	0.33
UCEC	chr20	35287101	Nonsense_Mutation	rs773380819	R560*	0.46
UCEC	chr20	35287107	Missense_Mutation	novel	L558M	0.1
UCEC	chr20	35287714	Silent	NA	P355P	0.22
UCEC	chr20	35287804	Silent	novel	P325P	0.27
UCEC	chr20	35288814	Missense_Mutation	NA	D220N	0.14	FAM83
UCEC	chr20	35291805	Missense_Mutation	rs752031109	S167N	0.33	FAM83
UCEC	chr20	35286765	Missense_Mutation	rs138265873	R672W	0.42
UCEC	chr20	35287036	Missense_Mutation	novel	E581D	0.3

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0209	0.14746

Survival Analysis

Cancer	P-value	Q-value
STAD	0.047	Kaplan-Meier Survival Analysis
ACC	0.038	Kaplan-Meier Survival Analysis
HNSC	0.0064	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
LUSC	0.012	Kaplan-Meier Survival Analysis
KIRP	0.048	Kaplan-Meier Survival Analysis
BLCA	0.042	Kaplan-Meier Survival Analysis
CESC	0.01	Kaplan-Meier Survival Analysis
LAML	0.037	Kaplan-Meier Survival Analysis
UCEC	0.0084	Kaplan-Meier Survival Analysis
LIHC	0.016	Kaplan-Meier Survival Analysis