EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000126001 (Gene tree)
Gene ID: 11190
Gene Symbol: CEP250
Alias: C-NAP1|CEP2
Full Name: centrosomal protein 250
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 64,142 bases
Position: chr20:35,455,139-35,519,280
Accession: 1859
RBP type: non-canonical RBP
Summary: This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000446710	CEP250-208	868	-	ENSP00000398747	164 (aa)	-	Q5JWS5
ENST00000621352	CEP250-214	607	-	ENSP00000482323	34 (aa)	-	A0A087WZ34
ENST00000425525	CEP250-206	918	-	ENSP00000394346	138 (aa)	-	H7C0D6
ENST00000461386	CEP250-209	2295	-	ENSP00000419137	538 (aa)	-	E9PHT2
ENST00000425934	CEP250-207	2156	-	ENSP00000413827	684 (aa)	-	E7ETF9
ENST00000474829	CEP250-211	356	-	-	- (aa)	-	-
ENST00000420564	CEP250-203	702	-	ENSP00000414651	114 (aa)	-	Q5JWS6
ENST00000422671	CEP250-204	2648	-	ENSP00000395992	877 (aa)	-	H7C0P0
ENST00000397524	CEP250-201	1419	-	ENSP00000380658	339 (aa)	-	A6PVI9
ENST00000397527	CEP250-202	15703	XM_005260262	ENSP00000380661	2442 (aa)	XP_005260319	Q9BV73
ENST00000425096	CEP250-205	629	-	ENSP00000400200	210 (aa)	-	H0Y5R2
ENST00000465987	CEP250-210	380	-	-	- (aa)	-	-
ENST00000476146	CEP250-212	550	-	-	- (aa)	-	-
ENST00000487467	CEP250-213	341	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000126001's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000126001	Body Height	3E-24	25429064
ENSG00000126001	Body Height	2E-6	20189936

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000126001	rs2236164	20	35509524	C	Height	20189936	[0.04-0.08] cm increase	0.06	EFO_0004339
ENSG00000126001	rs2236164	20	35509524	T	Height	25429064	[0.039-0.067] unit decrease	0.053	EFO_0004339

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000126001's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000086	G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0000278	mitotic cell cycle	12140259.	IDA	Process
GO:0005515	protein binding	10880350.20300119.20708153.	IPI	Function
GO:0005813	centrosome	9647649.21399614.	IDA	Component
GO:0005814	centriole	18851962.24421332.26337392.27623382.	IDA	Component
GO:0005814	centriole	11076968.	IDA	Component
GO:0005815	microtubule organizing center	9647649.	NAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005929	cilium	-	IEA	Component
GO:0008022	protein C-terminus binding	18851962.	IPI	Function
GO:0008104	protein localization	18851962.23213374.	IMP	Process
GO:0010389	regulation of G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0010457	centriole-centriole cohesion	11076968.18851962.23213374.24554434.	IMP	Process
GO:0019901	protein kinase binding	9647649.	IPI	Function
GO:0019904	protein domain specific binding	24554434.	IPI	Function
GO:0030997	regulation of centriole-centriole cohesion	9647649.	IDA	Process
GO:0032991	protein-containing complex	10880350.	IMP	Component
GO:0033365	protein localization to organelle	24554434.	IMP	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0097711	ciliary basal body-plasma membrane docking	-	TAS	Process
GO:1904781	positive regulation of protein localization to centrosome	27623382.	IMP	Process
GO:1905515	non-motile cilium assembly	23789104.	IMP	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr20	35475593	Nonsense_Mutation	novel	E555*	0.39
ACC	chr20	35502723	Nonsense_Mutation	novel	E1452*	0.52
BLCA	chr20	35475554	Silent	NA	L542L	0.28
BLCA	chr20	35498698	Missense_Mutation	NA	W1253C	0.77
BLCA	chr20	35504633	Missense_Mutation	novel	E2088D	0.29
BLCA	chr20	35496613	Silent	novel	L1068L	0.33
BLCA	chr20	35479228	Splice_Region	novel		0.13
BLCA	chr20	35472670	Splice_Region	novel		0.34
BLCA	chr20	35467326	Missense_Mutation	novel	E208Q	0.17
BLCA	chr20	35503757	Silent	novel	L1796L	0.18
BLCA	chr20	35503773	Missense_Mutation	novel	Q1802K	0.16
BLCA	chr20	35473404	Missense_Mutation	novel	E414K	0.48
BLCA	chr20	35503842	Missense_Mutation	novel	E1825K	0.26
BLCA	chr20	35467488	Missense_Mutation	novel	E262K	0.45
BLCA	chr20	35497851	Missense_Mutation	NA	A1147T	0.58
BLCA	chr20	35466060	Silent	novel	V116V	0.53
BLCA	chr20	35504028	Missense_Mutation	rs147660483	E1887K	0.42
BLCA	chr20	35466203	Frame_Shift_Ins	novel	*F165Lfs37**	0.12
BLCA	chr20	35502539	Silent	novel	L1390L	0.1
BLCA	chr20	35502992	Missense_Mutation	NA	Q1541H	0.08
BLCA	chr20	35469896	Silent	NA	T286T	0.14
BLCA	chr20	35500094	Missense_Mutation	novel	D1275H	0.26
BLCA	chr20	35496602	Missense_Mutation	novel	E1065K	0.15
BLCA	chr20	35466180	Silent	novel	E156E	0.44
BLCA	chr20	35494595	Silent	novel	E1035E	0.19
BLCA	chr20	35503475	Missense_Mutation	NA	Q1702H	0.42
BLCA	chr20	35503236	Silent	novel	R1623R	0.07
BLCA	chr20	35510040	Missense_Mutation	novel	E2351K	0.37
BLCA	chr20	35469936	Missense_Mutation	NA	E300K	0.38
BLCA	chr20	35466983	Silent	novel	L170L	0.28
BRCA	chr20	35507774	Missense_Mutation	novel	E2225Q	0.1
BRCA	chr20	35469936	Nonsense_Mutation	NA	E300*	0.14
BRCA	chr20	35466128	Missense_Mutation	NA	E139G	0.14
BRCA	chr20	35503388	Missense_Mutation	NA	Q1673H	0.74
BRCA	chr20	35494557	Missense_Mutation	NA	D1023N	0.1
BRCA	chr20	35503358	Silent	NA	Q1663Q	0.4
BRCA	chr20	35504848	Missense_Mutation	rs542508593	R2160T	0.07
BRCA	chr20	35490697	Frame_Shift_Ins	NA	*M885Nfs106**	0.16
BRCA	chr20	35469980	Silent	NA	E314E	0.19
BRCA	chr20	35504846	Silent	NA	L2159L	0.25
BRCA	chr20	35496592	Silent	NA	L1061L	0.41
BRCA	chr20	35497929	Missense_Mutation	rs377120249	G1173R	0.14
BRCA	chr20	35504546	Silent	rs112052000	Q2059Q	0.61
BRCA	chr20	35498630	Missense_Mutation	NA	P1231T	0.13
BRCA	chr20	35473401	Missense_Mutation	novel	Q413E	0.16
BRCA	chr20	35502672	Missense_Mutation	NA	E1435Q	0.17
BRCA	chr20	35503634	Silent	novel	L1755L	0.1
BRCA	chr20	35504818	Missense_Mutation	rs759294916	R2150Q	0.44
BRCA	chr20	35510027	Silent	rs776127915	A2346A	0.37
BRCA	chr20	35475566	Missense_Mutation	novel	R546G	0.03
BRCA	chr20	35466971	Silent	novel	F166F	0.18
CESC	chr20	35467017	Missense_Mutation	rs775018359	R182W	0.4
CESC	chr20	35480011	Missense_Mutation	novel	E818K	0.63
CESC	chr20	35502929	Silent	NA	Q1520Q	0.39
CESC	chr20	35502789	Silent	novel	L1474L	0.19
CESC	chr20	35479414	Splice_Site	novel	X761_splice	0.16
CESC	chr20	35508076	Silent	novel	E2264E	0.19
CESC	chr20	35472136	Missense_Mutation	NA	I345M	0.04
CESC	chr20	35467035	Nonsense_Mutation	novel	R188*	0.17
CESC	chr20	35522225	3'Flank	NA		0.43
CESC	chr20	35497875	Nonsense_Mutation	rs749314857	R1155*	0.45
CESC	chr20	35501856	Missense_Mutation	novel	W1304R	0.46
CESC	chr20	35522469	3'Flank	novel		0.38
CESC	chr20	35504229	Missense_Mutation	novel	H1954Y	0.11
CESC	chr20	35491232	Missense_Mutation	rs145916875	K925N	0.52
CESC	chr20	35467426	Missense_Mutation	NA	R241L	0.28
CESC	chr20	35491314	Nonsense_Mutation	NA	Q953*	0.16
CESC	chr20	35508182	Missense_Mutation	NA	L2300M	0.45
CESC	chr20	35507770	Missense_Mutation	novel	E2223D	0.49
CESC	chr20	35521069	3'Flank	novel		0.47
CHOL	chr20	35466109	Missense_Mutation	novel	A133T	0.34
CHOL	chr20	35522758	3'Flank	novel		0.22
CHOL	chr20	35503682	Silent	novel	L1771L	0.5
COAD	chr20	35467352	Silent	NA	L216L	0.26
COAD	chr20	35467455	Missense_Mutation	NA	A251T	0.37
COAD	chr20	35476475	Frame_Shift_Del	novel	*S582Ffs2**	0.13
COAD	chr20	35466074	Missense_Mutation	rs781762969	R121Q	0.39
COAD	chr20	35496641	Nonsense_Mutation	NA	R1078*	0.3
COAD	chr20	35502490	Missense_Mutation	NA	A1374D	0.38
COAD	chr20	35503700	Missense_Mutation	NA	E1777D	0.51
COAD	chr20	35500048	Splice_Site	NA	X1260_splice	0.29
COAD	chr20	35497881	Missense_Mutation	rs77804973	R1157C	0.09
COAD	chr20	35497929	Missense_Mutation	rs377120249	G1173R	0.35
COAD	chr20	35504327	Silent	NA	E1986E	0.21
COAD	chr20	35504911	Missense_Mutation	novel	A2181V	0.24
COAD	chr20	35467327	Missense_Mutation	NA	E208G	0.41
COAD	chr20	35473471	Missense_Mutation	rs200183326	R436Q	0.39
COAD	chr20	35504797	Missense_Mutation	NA	S2143Y	0.28
COAD	chr20	35467374	Missense_Mutation	novel	T224A	0.28
COAD	chr20	35478098	Silent	NA	S697S	0.31
COAD	chr20	35503347	Silent	NA	L1660L	0.52
COAD	chr20	35497875	Nonsense_Mutation	rs749314857	R1155*	0.52
COAD	chr20	35473384	Missense_Mutation	novel	Q407R	0.15
COAD	chr20	35479739	Silent	novel	I794I	0.16
COAD	chr20	35497782	Silent	NA	L1124L	0.36
COAD	chr20	35478094	Frame_Shift_Del	NA	*E698Hfs36**	0.27
COAD	chr20	35504614	Missense_Mutation	novel	Q2082R	0.27
COAD	chr20	35504837	Missense_Mutation	novel	Q2156H	0.34
COAD	chr20	35490646	Missense_Mutation	rs773558951	R866C	0.16
COAD	chr20	35467329	Frame_Shift_Del	novel	*H209Pfs6**	0.11
COAD	chr20	35502626	Silent	NA	L1419L	0.25
COAD	chr20	35498636	Silent	novel	L1233L	0.06
COAD	chr20	35467022	Silent	NA	E183E	0.19
COAD	chr20	35497914	Missense_Mutation	rs781608093	A1168T	0.34
COAD	chr20	35476596	Splice_Site	novel	X621_splice	0.24
COAD	chr20	35504475	Missense_Mutation	rs555985621	D2036N	0.43
COAD	chr20	35465797	Silent	novel	L100L	0.38
COAD	chr20	35498694	Missense_Mutation	novel	L1252P	0.35
COAD	chr20	35494624	Missense_Mutation	rs763406705	R1045Q	0.18
COAD	chr20	35462355	5'UTR	novel		0.25
COAD	chr20	35470130	Intron	novel		0.12
COAD	chr20	35467369	Missense_Mutation	rs78174774	R222H	0.21
COAD	chr20	35511450	Missense_Mutation	novel	A2385T	0.22
ESCA	chr20	35467428	Nonsense_Mutation	novel	E242*	0.14
ESCA	chr20	35501943	Missense_Mutation	novel	E1333K	0.41
ESCA	chr20	35502764	Silent	rs377306728	L1465L	0.32
ESCA	chr20	35504714	Missense_Mutation	novel	E2115D	0.17
GBM	chr20	35502640	Missense_Mutation	novel	A1424V	0.16
GBM	chr20	35504893	Missense_Mutation	novel	D2175G	0.17
GBM	chr20	35467036	Missense_Mutation	rs755314316	R188Q	0.19
GBM	chr20	35469897	Missense_Mutation	rs142201582	E287K	0.22
GBM	chr20	35504256	Missense_Mutation	novel	A1963T	0.38
GBM	chr20	35500049	Missense_Mutation	novel	D1260Y	0.05
GBM	chr20	35476454	Missense_Mutation	novel	E574D	0.41
GBM	chr20	35490781	Nonsense_Mutation	novel	Q911*	0.2
GBM	chr20	35476476	Missense_Mutation	novel	S582G	0.11
GBM	chr20	35510035	Missense_Mutation	novel	V2349G	0.04
GBM	chr20	35490700	Missense_Mutation	novel	K884E	0.08
GBM	chr20	35504468	Silent	novel	Y2033Y	0.42
GBM	chr20	35479235	Missense_Mutation	rs377363130	R700H	0.35
GBM	chr20	35504460	Missense_Mutation	NA	L2031V	0.48
HNSC	chr20	35466987	Missense_Mutation	novel	G172R	0.2
HNSC	chr20	35502918	Silent	novel	R1517R	0.47
HNSC	chr20	35509998	Missense_Mutation	novel	D2337N	0.13
HNSC	chr20	35511574	Missense_Mutation	novel	G2426V	0.33
HNSC	chr20	35503032	Missense_Mutation	novel	L1555V	0.24
HNSC	chr20	35503542	Missense_Mutation	novel	E1725Q	0.41
HNSC	chr20	35508180	Missense_Mutation	novel	T2299I	0.24
HNSC	chr20	35511683	3'UTR	rs182066632		0.41
HNSC	chr20	35465784	Missense_Mutation	novel	N95K	0.25
HNSC	chr20	35470088	Intron	novel		0.25
HNSC	chr20	35501844	Splice_Site	novel	X1300_splice	0.5
HNSC	chr20	35490754	Nonsense_Mutation	novel	Q902*	0.1
HNSC	chr20	35504210	Silent	novel	A1947A	0.19
HNSC	chr20	35504024	Silent	novel	L1885L	0.23
HNSC	chr20	35503500	Missense_Mutation	novel	E1711Q	0.05
HNSC	chr20	35504451	Missense_Mutation	novel	D2028N	0.17
KICH	chr20	35462465	Missense_Mutation	novel	E33A	0.19
KIRC	chr20	35465742	Splice_Site	NA	X82_splice	0.2
KIRC	chr20	35503512	Missense_Mutation	rs757984729	G1715S	0.17
KIRC	chr20	35511430	Missense_Mutation	novel	A2378V	0.22
KIRP	chr20	35504098	Missense_Mutation	novel	C1910Y	0.42
KIRP	chr20	35503623	Frame_Shift_Del	novel	*D1753Tfs14**	0.37
KIRP	chr20	35479298	Missense_Mutation	novel	E721G	0.3
KIRP	chr20	35476552	Frame_Shift_Ins	novel	*L608Ffs5**	0.31
KIRP	chr20	35511598	Missense_Mutation	novel	P2434L	0.59
KIRP	chr20	35503405	Missense_Mutation	novel	K1679M	0.19
KIRP	chr20	35504533	Missense_Mutation	NA	Q2055R	0.3
KIRP	chr20	35497956	Missense_Mutation	novel	L1182V	0.19
LAML	chr20	35479982	Missense_Mutation	novel	V808E	0.06
LAML	chr20	35479368	Silent	novel	R744R	0.05
LAML	chr20	35502733	Missense_Mutation	novel	K1455M	0.05
LGG	chr20	35496581	Missense_Mutation	novel	T1058A	0.4
LGG	chr20	35472088	Silent	NA	S329S	0.15
LGG	chr20	35503286	Silent	NA	I1639I	0.45
LGG	chr20	35504977	Missense_Mutation	novel	E2203G	0.26
LGG	chr20	35511493	Missense_Mutation	novel	A2399V	0.29
LIHC	chr20	35504371	Missense_Mutation	novel	L2001Q	0.45
LIHC	chr20	35503142	Silent	rs562343473	T1591T	0.4
LIHC	chr20	35502513	Silent	rs151254784	R1382R	0.15
LIHC	chr20	35475530	Missense_Mutation	novel	K534E	0.3
LIHC	chr20	35477900	Missense_Mutation	NA	S631R	0.48
LIHC	chr20	35479724	Missense_Mutation	NA	Q789H	0.34
LIHC	chr20	35503528	Missense_Mutation	novel	Q1720L	0.36
LIHC	chr20	35479333	Missense_Mutation	rs376769176	A733T	0.3
LIHC	chr20	35469958	Missense_Mutation	NA	K307R	0.45
LUAD	chr20	35501950	Missense_Mutation	novel	Q1335R	0.07
LUAD	chr20	35503057	Missense_Mutation	NA	E1563V	0.25
LUAD	chr20	35473877	Nonsense_Mutation	novel	E466*	0.07
LUAD	chr20	35490742	Missense_Mutation	NA	M898V	0.07
LUAD	chr20	35504701	Missense_Mutation	novel	L2111Q	0.26
LUAD	chr20	35503533	Missense_Mutation	novel	G1722W	0.19
LUAD	chr20	35491308	Silent	NA	L951L	0.2
LUAD	chr20	35504572	Missense_Mutation	novel	R2068M	0.19
LUAD	chr20	35503995	Missense_Mutation	novel	A1876S	0.88
LUAD	chr20	35493439	Missense_Mutation	novel	G967V	0.15
LUAD	chr20	35503125	Nonsense_Mutation	novel	Q1586*	0.11
LUAD	chr20	35503897	Missense_Mutation	novel	L1843P	0.48
LUAD	chr20	35503798	Missense_Mutation	NA	R1810T	0.16
LUAD	chr20	35477974	Missense_Mutation	novel	A656G	0.62
LUAD	chr20	35479389	Silent	novel	D751D	0.17
LUAD	chr20	35502992	Missense_Mutation	NA	Q1541H	0.07
LUSC	chr20	35466039	Missense_Mutation	rs753546802	R109S	0.21
LUSC	chr20	35498043	Missense_Mutation	novel	P1211S	0.42
LUSC	chr20	35477943	Missense_Mutation	novel	D646N	0.57
LUSC	chr20	35511627	3'UTR	novel		0.09
LUSC	chr20	35469996	Intron	rs769949861		0.28
LUSC	chr20	35501963	Silent	novel	A1339A	0.28
LUSC	chr20	35501964	Nonsense_Mutation	novel	Q1340*	0.29
LUSC	chr20	35511406	Missense_Mutation	NA	K2370R	0.54
LUSC	chr20	35503783	In_Frame_Ins	novel	L1805_D1806insSTHTHIHPQ	0.08
LUSC	chr20	35503785	Missense_Mutation	novel	D1806H	0.01
LUSC	chr20	35504206	Missense_Mutation	rs764314512	R1946Q	0.86
LUSC	chr20	35498010	Missense_Mutation	novel	R1200W	0.35
LUSC	chr20	35473412	Silent	novel	V416V	0.48
LUSC	chr20	35511419	Silent	NA	I2374I	0.19
LUSC	chr20	35504153	Missense_Mutation	novel	W1928C	0.09
LUSC	chr20	35504846	Silent	novel	L2159L	0.27
LUSC	chr20	35504822	Missense_Mutation	novel	E2151D	0.15
LUSC	chr20	35462404	Frame_Shift_Del	novel	*Q14Sfs29**	0.44
LUSC	chr20	35476524	Missense_Mutation	novel	A598T	0.23
LUSC	chr20	35475576	Missense_Mutation	novel	L549Q	0.24
LUSC	chr20	35503655	Silent	novel	L1762L	0.86
LUSC	chr20	35477962	Missense_Mutation	novel	K652T	0.36
LUSC	chr20	35465813	Missense_Mutation	novel	E105G	0.07
LUSC	chr20	35511492	Missense_Mutation	novel	A2399S	0.29
LUSC	chr20	35467003	Missense_Mutation	novel	L177H	0.54
LUSC	chr20	35511453	Missense_Mutation	novel	G2386C	0.54
LUSC	chr20	35502596	Silent	novel	G1409G	0.35
OV	chr20	35511424	Missense_Mutation	rs374274791	R2376H	0.18
OV	chr20	35475622	Frame_Shift_Del	novel	*E565Kfs2**	0.05
OV	chr20	35508181	Silent	NA	T2299T	0.16
OV	chr20	35502612	Missense_Mutation	NA	Q1415E	0.36
OV	chr20	35508169	Missense_Mutation	novel	Q2295H	0.04
OV	chr20	35469900	Missense_Mutation	novel	L288V	0.09
OV	chr20	35472761	Missense_Mutation	novel	D380A	0.04
OV	chr20	35504029	Missense_Mutation	rs768431825	E1887G	0.55
OV	chr20	35500144	Silent	novel	Q1291Q	0.07
OV	chr20	35496711	Missense_Mutation	rs756857780	A1101V	0.49
OV	chr20	35501889	Silent	NA	L1315L	0.37
OV	chr20	35490787	Frame_Shift_Ins	novel	*E913Afs78**	0.04
OV	chr20	35503254	Missense_Mutation	NA	D1629N	0.14
PAAD	chr20	35493504	Missense_Mutation	novel	D989N	0.23
PCPG	chr20	35511559	Missense_Mutation	novel	S2421N	0.41
PRAD	chr20	35472796	Missense_Mutation	rs370543710	R392C	0.35
PRAD	chr20	35479234	Missense_Mutation	rs777235501	R700C	0.38
PRAD	chr20	35503409	Silent	novel	I1680I	0.33
PRAD	chr20	35511492	Missense_Mutation	novel	A2399T	0.14
READ	chr20	35472713	Missense_Mutation	NA	G364D	0.32
READ	chr20	35511596	Missense_Mutation	NA	S2433R	0.19
READ	chr20	35497974	Missense_Mutation	novel	A1188S	0.59
READ	chr20	35511470	Silent	NA	L2391L	0.24
READ	chr20	35478066	Nonsense_Mutation	novel	E687*	0.34
READ	chr20	35496641	Nonsense_Mutation	NA	R1078*	0.38
SARC	chr20	35503103	Missense_Mutation	rs781717794	E1578D	0.12
SARC	chr20	35490697	Missense_Mutation	novel	E883K	0.4
SARC	chr20	35490698	Frame_Shift_Del	NA	*M885Wfs5**	0.42
SARC	chr20	35504540	Silent	novel	R2057R	0.11
SARC	chr20	35511696	3'UTR	novel		0.19
SKCM	chr20	35479347	Silent	NA	E737E	0.34
SKCM	chr20	35466060	Silent	novel	V116V	0.26
SKCM	chr20	35493549	Missense_Mutation	rs752918699	D1004N	0.43
SKCM	chr20	35466999	Missense_Mutation	rs150110885	R176C	0.22
SKCM	chr20	35508175	Silent	novel	R2297R	0.12
SKCM	chr20	35504296	Missense_Mutation	novel	A1976V	0.24
SKCM	chr20	35500085	Missense_Mutation	rs150723097	R1272C	0.31
SKCM	chr20	35504081	Silent	NA	L1904L	0.33
SKCM	chr20	35508181	Silent	NA	T2299T	0.32
SKCM	chr20	35494624	Missense_Mutation	rs763406705	R1045Q	0.34
SKCM	chr20	35511387	Missense_Mutation	NA	T2364P	0.16
SKCM	chr20	35490758	Missense_Mutation	NA	A903V	0.43
SKCM	chr20	35494654	Missense_Mutation	novel	A1055V	0.4
SKCM	chr20	35494655	Splice_Region	novel	A1055A	0.4
SKCM	chr20	35466151	Missense_Mutation	NA	R147G	0.43
SKCM	chr20	35503629	Nonsense_Mutation	NA	Q1754*	0.33
SKCM	chr20	35504322	Missense_Mutation	NA	L1985F	0.33
SKCM	chr20	35503328	Silent	NA	L1653L	0.34
SKCM	chr20	35508124	Silent	novel	A2280A	0.29
SKCM	chr20	35508125	Missense_Mutation	rs148942784	R2281W	0.3
SKCM	chr20	35503371	Nonsense_Mutation	NA	Q1668*	0.39
SKCM	chr20	35498047	Missense_Mutation	novel	S1212F	0.14
SKCM	chr20	35504514	Missense_Mutation	NA	E2049K	0.22
SKCM	chr20	35467368	Missense_Mutation	NA	R222S	0.25
SKCM	chr20	35467005	Missense_Mutation	novel	L178F	0.2
SKCM	chr20	35502951	Missense_Mutation	NA	L1528F	0.33
SKCM	chr20	35503685	Silent	rs775770000	L1772L	0.33
SKCM	chr20	35497881	Missense_Mutation	rs77804973	R1157C	0.5
SKCM	chr20	35508073	Missense_Mutation	novel	M2263I	0.43
SKCM	chr20	35504646	Missense_Mutation	NA	H2093Y	0.17
SKCM	chr20	35467440	Silent	NA	L246L	0.1
SKCM	chr20	35508042	Missense_Mutation	rs749167005	G2253E	0.18
SKCM	chr20	35498044	Missense_Mutation	rs780050066	P1211L	0.57
SKCM	chr20	35504134	Missense_Mutation	NA	R1922K	0.27
SKCM	chr20	35472145	Frame_Shift_Del	novel	*I348Mfs10**	0.14
SKCM	chr20	35501917	Missense_Mutation	rs757984899	S1324F	0.36
SKCM	chr20	35502954	Silent	NA	L1529L	0.39
SKCM	chr20	35503212	Missense_Mutation	NA	E1615K	0.48
STAD	chr20	35473943	Missense_Mutation	rs151167358	R488C	0.35
STAD	chr20	35504875	Nonsense_Mutation	novel	W2169*	0.33
STAD	chr20	35490698	Frame_Shift_Del	NA	*M885Wfs5**	0.11
STAD	chr20	35504977	Missense_Mutation	NA	E2203A	0.3
STAD	chr20	35467408	Missense_Mutation	NA	S235Y	0.09
STAD	chr20	35511615	Missense_Mutation	rs748792917	A2440T	0.54
STAD	chr20	35490697	Frame_Shift_Ins	NA	*M885Nfs106**	0.38
STAD	chr20	35503901	Missense_Mutation	NA	Q1844H	0.13
STAD	chr20	35469973	Missense_Mutation	rs778255060	T312I	0.43
STAD	chr20	35498028	Frame_Shift_Del	novel	*G1207Efs27**	0.4
STAD	chr20	35502571	Missense_Mutation	novel	R1401I	0.32
STAD	chr20	35479366	Missense_Mutation	rs199810583	R744W	0.25
STAD	chr20	35504463	Nonsense_Mutation	rs773637285	R2032*	0.31
STAD	chr20	35466073	Nonsense_Mutation	NA	R121*	0.17
STAD	chr20	35467036	Missense_Mutation	rs755314316	R188Q	0.42
STAD	chr20	35511508	Missense_Mutation	NA	A2404V	0.3
STAD	chr20	35502852	Missense_Mutation	novel	A1495T	0.38
STAD	chr20	35503452	Nonsense_Mutation	rs746831149	R1695*	0.46
STAD	chr20	35504818	Missense_Mutation	rs759294916	R2150Q	0.19
STAD	chr20	35475627	Missense_Mutation	NA	V566G	0.17
STAD	chr20	35467425	Missense_Mutation	novel	R241W	0.14
STAD	chr20	35491297	Missense_Mutation	NA	Q947P	0.3
STAD	chr20	35502695	Silent	novel	G1442G	0.13
STAD	chr20	35503455	Missense_Mutation	novel	G1696S	0.24
STAD	chr20	35462504	Missense_Mutation	novel	Q46R	0.32
STAD	chr20	35502974	Missense_Mutation	NA	D1535E	0.23
STAD	chr20	35479366	Missense_Mutation	rs199810583	R744W	0.25
STAD	chr20	35472796	Missense_Mutation	rs370543710	R392C	0.31
STAD	chr20	35496656	Missense_Mutation	NA	S1083G	0.54
STAD	chr20	35503904	Silent	novel	G1845G	0.36
STAD	chr20	35480014	Missense_Mutation	NA	R819W	0.3
STAD	chr20	35472795	Silent	NA	V391V	0.06
STAD	chr20	35503452	Nonsense_Mutation	rs746831149	R1695*	0.1
THCA	chr20	35462315	5'UTR	novel		0.5
THCA	chr20	35500098	Missense_Mutation	rs773870781	T1276I	0.39
THCA	chr20	35503561	In_Frame_Ins	novel	L1731_R1732insLQ	0.03
THYM	chr20	35479991	Missense_Mutation	novel	L811P	0.08
UCEC	chr20	35511776	3'UTR	novel		0.37
UCEC	chr20	35502888	Missense_Mutation	novel	R1507W	0.14
UCEC	chr20	35504742	Missense_Mutation	novel	L2125V	0.31
UCEC	chr20	35508977	Missense_Mutation	novel	A2314V	0.17
UCEC	chr20	35478084	Missense_Mutation	NA	Q693K	0.39
UCEC	chr20	35490739	Missense_Mutation	NA	E897K	0.22
UCEC	chr20	35496665	Missense_Mutation	rs143143244	R1086C	0.36
UCEC	chr20	35497813	Missense_Mutation	rs545422424	T1134M	0.25
UCEC	chr20	35504582	Silent	NA	E2071E	0.22
UCEC	chr20	35522029	3'Flank	novel		0.1
UCEC	chr20	35497781	Missense_Mutation	novel	Q1123H	0.5
UCEC	chr20	35503984	Missense_Mutation	novel	E1872G	0.13
UCEC	chr20	35478080	Missense_Mutation	novel	E691D	0.3
UCEC	chr20	35466157	Missense_Mutation	rs373038487	R149W	0.45
UCEC	chr20	35511683	3'UTR	rs182066632		0.39
UCEC	chr20	35501951	Silent	novel	Q1335Q	0.34
UCEC	chr20	35472796	Missense_Mutation	rs370543710	R392C	0.41
UCEC	chr20	35522572	3'Flank	novel		0.21
UCEC	chr20	35472722	Missense_Mutation	novel	N367T	0.04
UCEC	chr20	35502410	Missense_Mutation	NA	Q1347H	0.23
UCEC	chr20	35503452	Nonsense_Mutation	rs746831149	R1695*	0.25
UCEC	chr20	35503456	Missense_Mutation	NA	G1696D	0.16
UCEC	chr20	35503801	Missense_Mutation	NA	A1811V	0.33
UCEC	chr20	35473392	Missense_Mutation	novel	A410T	0.16
UCEC	chr20	35497872	Missense_Mutation	novel	L1154M	0.3
UCEC	chr20	35502690	Missense_Mutation	rs533821058	R1441W	0.17
UCEC	chr20	35503287	Missense_Mutation	rs755541063	E1640K	0.48
UCEC	chr20	35508999	Silent	NA	G2321G	0.44
UCEC	chr20	35510048	Missense_Mutation	NA	Q2353H	0.47
UCEC	chr20	35470016	Intron	novel		0.51
UCEC	chr20	35472060	Missense_Mutation	novel	H320P	0.25
UCEC	chr20	35522239	3'Flank	novel		0.33
UCEC	chr20	35522558	3'Flank	novel		0.37
UCEC	chr20	35479256	Missense_Mutation	rs139645049	T707M	0.15
UCEC	chr20	35503939	Missense_Mutation	rs73903079	R1857H	0.22
UCEC	chr20	35501934	Missense_Mutation	rs773111712	R1330W	0.36
UCEC	chr20	35504245	Missense_Mutation	novel	A1959V	0.3
UCEC	chr20	35508155	Missense_Mutation	rs772146999	R2291C	0.55
UCEC	chr20	35502632	Missense_Mutation	novel	E1421D	0.49
UCEC	chr20	35491306	Missense_Mutation	rs372510691	R950Q	0.17
UCEC	chr20	35501884	Missense_Mutation	novel	S1313Y	0.48
UCEC	chr20	35503800	Missense_Mutation	rs767284222	A1811T	0.5
UCEC	chr20	35504625	Nonsense_Mutation	novel	E2086*	0.42
UCEC	chr20	35522421	3'Flank	novel		0.44
UCEC	chr20	35467305	Missense_Mutation	novel	D201N	0.45
UCEC	chr20	35472818	Missense_Mutation	NA	R399H	0.16
UCEC	chr20	35479645	Splice_Site	NA	X763_splice	0.35
UCEC	chr20	35469888	Splice_Site	novel	X284_splice	0.25
UCEC	chr20	35494623	Nonsense_Mutation	rs775811770	R1045*	0.35
UCEC	chr20	35491291	Missense_Mutation	novel	S945N	0.46
UCEC	chr20	35479353	Silent	NA	A739A	0.31
UCEC	chr20	35467445	Silent	novel	L247L	0.17
UCEC	chr20	35497882	Missense_Mutation	rs757635678	R1157H	0.33
UCEC	chr20	35470081	Intron	novel		0.39
UCEC	chr20	35504038	Missense_Mutation	novel	G1890E	0.19
UCEC	chr20	35503598	Silent	NA	E1743E	0.05
UCEC	chr20	35479667	Missense_Mutation	novel	E770D	0.53
UCEC	chr20	35503558	Missense_Mutation	novel	I1730S	0.5
UCEC	chr20	35475533	Nonsense_Mutation	novel	Q535*	0.09
UCEC	chr20	35497826	Silent	novel	L1138L	0.22
UCEC	chr20	35497875	Nonsense_Mutation	rs749314857	R1155*	0.56
UCEC	chr20	35504641	Missense_Mutation	novel	G2091D	0.41
UCEC	chr20	35504856	Nonsense_Mutation	novel	E2163*	0.54
UCEC	chr20	35494624	Missense_Mutation	rs763406705	R1045Q	0.38
UCEC	chr20	35472058	Missense_Mutation	novel	N319K	0.15
UCEC	chr20	35504166	Missense_Mutation	novel	A1933T	0.24
UCEC	chr20	35522207	3'Flank	rs149685601		0.3
UCEC	chr20	35502865	Missense_Mutation	rs756362141	R1499Q	0.4
UCEC	chr20	35522527	3'Flank	novel		0.41
UCEC	chr20	35479402	Missense_Mutation	rs143763293	A756T	0.14
UCEC	chr20	35503893	Missense_Mutation	rs747287126	A1842T	0.33
UCEC	chr20	35479378	Missense_Mutation	rs754323656	V748M	0.42
UCEC	chr20	35474020	Missense_Mutation	novel	E513D	0.46
UCEC	chr20	35502605	Silent	novel	K1412K	0.24
UCEC	chr20	35497995	Missense_Mutation	novel	S1195P	0.13
UCEC	chr20	35504650	Missense_Mutation	novel	Q2094R	0.14
UCEC	chr20	35473907	Missense_Mutation	novel	R476W	0.4
UCEC	chr20	35494624	Missense_Mutation	rs763406705	R1045Q	0.4
UCEC	chr20	35511615	Missense_Mutation	rs748792917	A2440T	0.31
UCEC	chr20	35473930	Silent	novel	E483E	0.16
UCEC	chr20	35477951	Silent	rs374906853	A648A	0.17
UCEC	chr20	35494595	Silent	novel	E1035E	0.44
UCEC	chr20	35502420	Nonsense_Mutation	novel	E1351*	0.18
UCEC	chr20	35502552	Missense_Mutation	novel	V1395I	0.51
UCEC	chr20	35503531	Missense_Mutation	rs375993979	R1721H	0.1
UCEC	chr20	35503913	Missense_Mutation	novel	E1848D	0.17
UCEC	chr20	35504330	Missense_Mutation	novel	Q1987H	0.26
UCEC	chr20	35511683	3'UTR	rs182066632		0.21
UCEC	chr20	35479291	Nonsense_Mutation	novel	R719*	0.39
UCEC	chr20	35522397	3'Flank	novel		0.6
UCEC	chr20	35497802	Silent	rs79678946	A1130A	0.39
UCEC	chr20	35503604	Silent	novel	I1745I	0.43
UCEC	chr20	35522077	3'Flank	novel		0.35
UCEC	chr20	35470063	Intron	novel		0.31
UCEC	chr20	35472818	Missense_Mutation	NA	R399H	0.36
UCEC	chr20	35479342	Nonsense_Mutation	novel	R736*	0.37
UCEC	chr20	35491326	Missense_Mutation	novel	V957I	0.32
UCEC	chr20	35497852	Missense_Mutation	novel	A1147V	0.33
UCEC	chr20	35504182	Missense_Mutation	novel	R1938Q	0.44
UCEC	chr20	35522717	3'Flank	novel		0.33
UCS	chr20	35503452	Nonsense_Mutation	rs746831149	R1695*	0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LAML	DEL	0.0209	0.14746

Survival Analysis

Cancer	P-value	Q-value
THYM	0.034	Kaplan-Meier Survival Analysis
KIRC	0.0088	Kaplan-Meier Survival Analysis
MESO	0.00019	Kaplan-Meier Survival Analysis
ACC	0.018	Kaplan-Meier Survival Analysis
PAAD	0.0001	Kaplan-Meier Survival Analysis
PCPG	0.027	Kaplan-Meier Survival Analysis
UCEC	0.0052	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LGG	0.034	Kaplan-Meier Survival Analysis
THCA	0.0029	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742