EuRBPDB

Description

Ensembl ID: ENSG00000126216 (Gene tree)
Gene ID: 10426
Gene Symbol: TUBGCP3
Alias: GCP3|Spc98p|SPBC98
Full Name: tubulin gamma complex associated protein 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 121,438 bases
Position: chr13:112,485,005-112,606,442
Accession: 18598
RBP type: non-canonical RBP
Summary: (Tubulin Gamma Complex Associated Protein 3) is a Protein Coding gene. Diseases associated with TUBGCP3 include Cardiomyopathy, Dilated, 1P. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. Gene Ontology (GO) annotations related to this gene include structural molecule activity and gamma-tubulin binding. An important paralog of this gene is TUBGCP6.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000483532	TUBGCP3-206	712	-	-	- (aa)	-	-
ENST00000375669	TUBGCP3-202	2723	XM_005268293	ENSP00000364821	824 (aa)	XP_005268350	Q96CW5
ENST00000464139	TUBGCP3-204	2461	-	ENSP00000478276	439 (aa)	-	A0A087WU06
ENST00000611152	TUBGCP3-207	1508	-	ENSP00000482912	129 (aa)	-	A0A087WZV5
ENST00000261965	TUBGCP3-201	3899	XM_011537462	ENSP00000261965	907 (aa)	XP_011535764	Q96CW5
ENST00000462580	TUBGCP3-203	915	-	-	- (aa)	-	-
ENST00000649778	TUBGCP3-208	4111	-	ENSP00000497715	612 (aa)	-	-
ENST00000469302	TUBGCP3-205	551	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000126216	Heart Failure	1.2621302E-004	-
ENSG00000126216	Heart Failure	7.0889599E-006	-
ENSG00000126216	Arteries	5.0210000E-005	-
ENSG00000126216	Calcium	5.9520000E-005	-
ENSG00000126216	Calcium	4.7180000E-005	-
ENSG00000126216	Calcium	8.0950000E-005	-
ENSG00000126216	Calcium	5.9520000E-005	-
ENSG00000126216	Asthma	8.3705930E-005	-
ENSG00000126216	Child Development Disorders, Pervasive	1.9000000E-005	-

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000126216	TUBGCP3	73	36.243	FBgn0001612	Grip91	73	36.243	Drosophila_melanogaster

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000278	mitotic cell cycle	21873635.	IBA	Process
GO:0000923	equatorial microtubule organizing center	21873635.	IBA	Component
GO:0000930	gamma-tubulin complex	21873635.	IBA	Component
GO:0005198	structural molecule activity	9566967.	NAS	Function
GO:0005200	structural constituent of cytoskeleton	9566969.	NAS	Function
GO:0005515	protein binding	9566969.17959831.	IPI	Function
GO:0005737	cytoplasm	9566969.	IDA	Component
GO:0005813	centrosome	21873635.	IBA	Component
GO:0005813	centrosome	9566969.21399614.	IDA	Component
GO:0005813	centrosome	11694571.	NAS	Component
GO:0005814	centriole	9566969.	IDA	Component
GO:0005819	spindle	7876350.	NAS	Component
GO:0005827	polar microtubule	9566969.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0007020	microtubule nucleation	9566969.11694571.	NAS	Process
GO:0007338	single fertilization	9138452.	NAS	Process
GO:0008275	gamma-tubulin small complex	21873635.	IBA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0031122	cytoplasmic microtubule organization	21873635.	IBA	Process
GO:0043015	gamma-tubulin binding	21873635.	IBA	Function
GO:0043015	gamma-tubulin binding	9566969.	IDA	Function
GO:0051011	microtubule minus-end binding	21873635.	IBA	Function
GO:0051225	spindle assembly	21873635.	IBA	Process
GO:0051321	meiotic cell cycle	21873635.	IBA	Process
GO:0051415	microtubule nucleation by interphase microtubule organizing center	21873635.	IBA	Process