EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

PRI

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000126524 (Gene tree)
Gene ID: 51119
Gene Symbol: SBDS
Alias: CGI-97|FLJ10917|SDS|SWDS
Full Name: SBDS ribosome maturation factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 7,925 bases
Position: chr7:66,987,677-66,995,601
Accession: 19440
RBP type: canonical RBP
Summary: This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000246868	SBDS	PF01172.18	2.4e-32	1	1
ENSP00000483040	SBDS	PF01172.18	3.5e-31	1	1
ENSP00000246868	SBDS_C	PF09377.10	8.8e-39	1	1
ENSP00000483040	SBDS_C	PF09377.10	8.8e-39	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000617799	SBDS-205	953	-	ENSP00000483040	250 (aa)	-	A0A087X020
ENST00000246868	SBDS-201	1631	-	ENSP00000246868	250 (aa)	-	Q9Y3A5
ENST00000463579	SBDS-203	513	-	-	- (aa)	-	-
ENST00000490953	SBDS-204	841	-	-	- (aa)	-	-
ENST00000414306	SBDS-202	1531	-	ENSP00000394586	86 (aa)	-	F8WE72

Gene Model

Click here to download ENSG00000126524's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000126524's network

CanvasJS.com

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000126524	SBDS	97	87.952	ENSAPOG00000014285	sbds	100	83.133	Acanthochromis_polyacanthus
ENSG00000126524	SBDS	100	98.800	ENSAMEG00000018167	SBDS	100	98.800	Ailuropoda_melanoleuca
ENSG00000126524	SBDS	97	89.157	ENSACIG00000007308	sbds	100	82.540	Amphilophus_citrinellus
ENSG00000126524	SBDS	97	87.952	ENSAOCG00000016770	sbds	100	83.133	Amphiprion_ocellaris
ENSG00000126524	SBDS	97	89.157	ENSAPEG00000015897	sbds	100	83.534	Amphiprion_percula
ENSG00000126524	SBDS	97	87.952	ENSATEG00000006901	sbds	100	83.534	Anabas_testudineus
ENSG00000126524	SBDS	92	92.641	ENSANAG00000024342	-	97	92.641	Aotus_nancymaae
ENSG00000126524	SBDS	83	99.517	ENSANAG00000037501	-	100	99.517	Aotus_nancymaae
ENSG00000126524	SBDS	97	89.157	ENSACLG00000018750	sbds	100	83.936	Astatotilapia_calliptera
ENSG00000126524	SBDS	100	84.400	ENSAMXG00000005361	sbds	100	84.400	Astyanax_mexicanus
ENSG00000126524	SBDS	100	98.800	ENSBTAG00000004051	SBDS	100	98.800	Bos_taurus
ENSG00000126524	SBDS	95	75.610	WBGene00021063	sbds-1	97	56.911	Caenorhabditis_elegans
ENSG00000126524	SBDS	100	98.800	ENSCJAG00000041007	SBDS	100	98.800	Callithrix_jacchus
ENSG00000126524	SBDS	100	97.222	ENSCAFG00000010797	SBDS	100	97.222	Canis_familiaris
ENSG00000126524	SBDS	100	99.200	ENSCAFG00020005357	SBDS	100	99.200	Canis_lupus_dingo
ENSG00000126524	SBDS	100	99.600	ENSCHIG00000026854	SBDS	100	99.600	Capra_hircus
ENSG00000126524	SBDS	100	100.000	ENSTSYG00000033822	SBDS	100	100.000	Carlito_syrichta
ENSG00000126524	SBDS	66	97.561	ENSCAPG00000006634	SBDS	100	97.561	Cavia_aperea
ENSG00000126524	SBDS	100	98.400	ENSCPOG00000036143	SBDS	100	98.400	Cavia_porcellus
ENSG00000126524	SBDS	100	99.600	ENSCCAG00000020671	SBDS	100	99.600	Cebus_capucinus
ENSG00000126524	SBDS	100	100.000	ENSCATG00000039026	SBDS	100	100.000	Cercocebus_atys
ENSG00000126524	SBDS	100	98.000	ENSCLAG00000005721	-	100	98.000	Chinchilla_lanigera
ENSG00000126524	SBDS	99	70.968	ENSCLAG00000002113	-	99	70.968	Chinchilla_lanigera
ENSG00000126524	SBDS	100	100.000	ENSCSAG00000018275	SBDS	100	100.000	Chlorocebus_sabaeus
ENSG00000126524	SBDS	97	100.000	ENSCHOG00000003795	SBDS	100	94.400	Choloepus_hoffmanni
ENSG00000126524	SBDS	100	89.600	ENSCPBG00000014893	SBDS	100	89.600	Chrysemys_picta_bellii
ENSG00000126524	SBDS	97	77.108	ENSCSAVG00000011811	-	100	66.800	Ciona_savignyi
ENSG00000126524	SBDS	100	99.600	ENSCANG00000032368	SBDS	100	99.600	Colobus_angolensis_palliatus
ENSG00000126524	SBDS	98	100.000	ENSCGRG00001000088	-	83	100.000	Cricetulus_griseus_chok1gshd
ENSG00000126524	SBDS	66	95.122	ENSCGRG00001019886	Sbds	100	95.122	Cricetulus_griseus_chok1gshd
ENSG00000126524	SBDS	83	96.135	ENSCGRG00000009211	Sbds	100	96.135	Cricetulus_griseus_crigri
ENSG00000126524	SBDS	97	85.542	ENSCSEG00000005798	sbds	100	81.526	Cynoglossus_semilaevis
ENSG00000126524	SBDS	97	90.361	ENSCVAG00000001053	sbds	100	81.526	Cyprinodon_variegatus
ENSG00000126524	SBDS	97	87.952	ENSDARG00000027803	sbds	100	84.000	Danio_rerio
ENSG00000126524	SBDS	100	98.800	ENSDNOG00000041174	SBDS	100	98.800	Dasypus_novemcinctus
ENSG00000126524	SBDS	100	96.000	ENSDORG00000026218	Sbds	100	96.000	Dipodomys_ordii
ENSG00000126524	SBDS	94	75.309	FBgn0035714	CG8549	99	59.036	Drosophila_melanogaster
ENSG00000126524	SBDS	93	57.940	ENSEBUG00000015780	sbds	100	57.940	Eptatretus_burgeri
ENSG00000126524	SBDS	100	99.600	ENSEASG00005008821	SBDS	100	99.600	Equus_asinus_asinus
ENSG00000126524	SBDS	100	99.600	ENSECAG00000008202	SBDS	100	99.600	Equus_caballus
ENSG00000126524	SBDS	83	76.442	ENSEEUG00000004768	SBDS	100	76.442	Erinaceus_europaeus
ENSG00000126524	SBDS	97	86.747	ENSELUG00000008382	sbds	100	82.000	Esox_lucius
ENSG00000126524	SBDS	100	99.200	ENSFCAG00000022142	SBDS	100	99.200	Felis_catus
ENSG00000126524	SBDS	100	89.200	ENSFALG00000013808	SBDS	100	89.200	Ficedula_albicollis
ENSG00000126524	SBDS	100	98.400	ENSFDAG00000018947	-	100	98.400	Fukomys_damarensis
ENSG00000126524	SBDS	97	85.542	ENSFHEG00000000708	sbds	100	78.313	Fundulus_heteroclitus
ENSG00000126524	SBDS	100	84.000	ENSGMOG00000018356	sbds	99	84.000	Gadus_morhua
ENSG00000126524	SBDS	100	89.200	ENSGALG00000027989	SBDS	100	89.200	Gallus_gallus
ENSG00000126524	SBDS	92	78.261	ENSGAFG00000014204	sbds	100	78.261	Gambusia_affinis
ENSG00000126524	SBDS	97	87.952	ENSGACG00000012697	sbds	100	82.329	Gasterosteus_aculeatus
ENSG00000126524	SBDS	86	89.720	ENSGAGG00000022402	SBDS	100	89.720	Gopherus_agassizii
ENSG00000126524	SBDS	97	100.000	ENSGGOG00000001472	-	87	98.851	Gorilla_gorilla
ENSG00000126524	SBDS	96	79.668	ENSGGOG00000040023	-	92	79.668	Gorilla_gorilla
ENSG00000126524	SBDS	97	89.157	ENSHBUG00000002660	sbds	100	83.936	Haplochromis_burtoni
ENSG00000126524	SBDS	100	96.800	ENSHGLG00000009671	SBDS	100	96.800	Heterocephalus_glaber_female
ENSG00000126524	SBDS	100	96.800	ENSHGLG00100011332	SBDS	100	96.800	Heterocephalus_glaber_male
ENSG00000126524	SBDS	97	89.157	ENSHCOG00000018606	sbds	100	81.526	Hippocampus_comes
ENSG00000126524	SBDS	100	85.200	ENSIPUG00000006536	sbds	100	85.200	Ictalurus_punctatus
ENSG00000126524	SBDS	98	98.810	ENSSTOG00000022203	-	90	98.824	Ictidomys_tridecemlineatus
ENSG00000126524	SBDS	97	91.860	ENSJJAG00000003934	-	100	70.356	Jaculus_jaculus
ENSG00000126524	SBDS	100	94.400	ENSJJAG00000012033	-	100	94.400	Jaculus_jaculus
ENSG00000126524	SBDS	97	85.542	ENSJJAG00000013791	-	100	87.619	Jaculus_jaculus
ENSG00000126524	SBDS	97	90.361	ENSKMAG00000018542	sbds	100	83.936	Kryptolebias_marmoratus
ENSG00000126524	SBDS	97	86.747	ENSLBEG00000016687	sbds	100	80.321	Labrus_bergylta
ENSG00000126524	SBDS	100	70.472	ENSLACG00000018916	SBDS	100	70.472	Latimeria_chalumnae
ENSG00000126524	SBDS	100	87.600	ENSLOCG00000004073	sbds	100	87.600	Lepisosteus_oculatus
ENSG00000126524	SBDS	100	98.000	ENSLAFG00000008763	SBDS	100	98.000	Loxodonta_africana
ENSG00000126524	SBDS	100	100.000	ENSMFAG00000032620	SBDS	100	100.000	Macaca_fascicularis
ENSG00000126524	SBDS	100	100.000	ENSMMUG00000045653	SBDS	100	100.000	Macaca_mulatta
ENSG00000126524	SBDS	100	100.000	ENSMNEG00000031523	SBDS	100	100.000	Macaca_nemestrina
ENSG00000126524	SBDS	97	90.805	ENSMLEG00000036826	SBDS	100	75.197	Mandrillus_leucophaeus
ENSG00000126524	SBDS	97	89.157	ENSMAMG00000016062	sbds	100	83.133	Mastacembelus_armatus
ENSG00000126524	SBDS	97	89.157	ENSMZEG00005024385	sbds	100	83.936	Maylandia_zebra
ENSG00000126524	SBDS	100	89.200	ENSMGAG00000002119	SBDS	100	89.200	Meleagris_gallopavo
ENSG00000126524	SBDS	97	86.747	ENSMAUG00000022214	-	100	76.707	Mesocricetus_auratus
ENSG00000126524	SBDS	97	100.000	ENSMAUG00000004862	-	91	86.408	Mesocricetus_auratus
ENSG00000126524	SBDS	100	99.200	ENSMICG00000014366	SBDS	100	99.200	Microcebus_murinus
ENSG00000126524	SBDS	100	97.600	ENSMOCG00000011739	Sbds	100	97.600	Microtus_ochrogaster
ENSG00000126524	SBDS	97	84.337	ENSMMOG00000005061	sbds	100	73.200	Mola_mola
ENSG00000126524	SBDS	97	100.000	ENSMODG00000006644	SBDS	100	96.800	Monodelphis_domestica
ENSG00000126524	SBDS	97	90.361	ENSMALG00000010219	sbds	100	83.133	Monopterus_albus
ENSG00000126524	SBDS	100	97.600	MGP_CAROLIEiJ_G0027800	Sbds	100	97.674	Mus_caroli
ENSG00000126524	SBDS	100	97.200	ENSMUSG00000025337	Sbds	100	97.674	Mus_musculus
ENSG00000126524	SBDS	100	97.200	MGP_PahariEiJ_G0024384	Sbds	100	97.674	Mus_pahari
ENSG00000126524	SBDS	100	97.200	MGP_SPRETEiJ_G0028798	Sbds	100	97.674	Mus_spretus
ENSG00000126524	SBDS	67	93.452	ENSMPUG00000016192	SBDS	97	93.452	Mustela_putorius_furo
ENSG00000126524	SBDS	73	97.253	ENSMLUG00000013575	SBDS	100	97.253	Myotis_lucifugus
ENSG00000126524	SBDS	100	97.600	ENSNGAG00000012093	Sbds	100	97.600	Nannospalax_galili
ENSG00000126524	SBDS	97	89.157	ENSNBRG00000017027	sbds	100	83.936	Neolamprologus_brichardi
ENSG00000126524	SBDS	100	100.000	ENSNLEG00000013288	SBDS	100	100.000	Nomascus_leucogenys
ENSG00000126524	SBDS	100	96.000	ENSOPRG00000008721	SBDS	100	96.000	Ochotona_princeps
ENSG00000126524	SBDS	97	100.000	ENSODEG00000015687	-	83	100.000	Octodon_degus
ENSG00000126524	SBDS	99	72.289	ENSODEG00000000137	-	85	75.600	Octodon_degus
ENSG00000126524	SBDS	97	81.928	ENSODEG00000001116	-	99	77.510	Octodon_degus
ENSG00000126524	SBDS	100	88.000	ENSODEG00000019253	-	84	88.000	Octodon_degus
ENSG00000126524	SBDS	97	89.157	ENSONIG00000005874	sbds	100	83.133	Oreochromis_niloticus
ENSG00000126524	SBDS	83	92.754	ENSOANG00000007674	-	100	92.754	Ornithorhynchus_anatinus
ENSG00000126524	SBDS	100	97.600	ENSOCUG00000003170	SBDS	100	97.600	Oryctolagus_cuniculus
ENSG00000126524	SBDS	97	84.337	ENSORLG00000023489	sbds	100	80.321	Oryzias_latipes
ENSG00000126524	SBDS	97	84.337	ENSORLG00020019282	sbds	100	79.920	Oryzias_latipes_hni
ENSG00000126524	SBDS	97	84.337	ENSORLG00015008005	sbds	100	79.920	Oryzias_latipes_hsok
ENSG00000126524	SBDS	97	85.542	ENSOMEG00000022747	sbds	100	80.723	Oryzias_melastigma
ENSG00000126524	SBDS	100	98.400	ENSOGAG00000009011	-	100	98.400	Otolemur_garnettii
ENSG00000126524	SBDS	100	82.000	ENSOGAG00000015036	-	100	82.000	Otolemur_garnettii
ENSG00000126524	SBDS	100	99.600	ENSOARG00000010609	SBDS	100	99.600	Ovis_aries
ENSG00000126524	SBDS	100	99.200	ENSPPAG00000043889	-	100	99.200	Pan_paniscus
ENSG00000126524	SBDS	100	99.200	ENSPPRG00000002307	SBDS	100	99.200	Panthera_pardus
ENSG00000126524	SBDS	100	99.200	ENSPTIG00000021308	SBDS	100	99.200	Panthera_tigris_altaica
ENSG00000126524	SBDS	100	100.000	ENSPTRG00000019254	SBDS	100	100.000	Pan_troglodytes
ENSG00000126524	SBDS	97	100.000	ENSPTRG00000048174	-	96	97.235	Pan_troglodytes
ENSG00000126524	SBDS	100	85.200	ENSPTRG00000050835	-	100	85.200	Pan_troglodytes
ENSG00000126524	SBDS	100	84.800	ENSPTRG00000047744	-	100	84.800	Pan_troglodytes
ENSG00000126524	SBDS	100	99.600	ENSPANG00000004078	SBDS	100	99.600	Papio_anubis
ENSG00000126524	SBDS	100	84.400	ENSPKIG00000006489	sbds	100	84.400	Paramormyrops_kingsleyae
ENSG00000126524	SBDS	83	90.338	ENSPSIG00000014603	SBDS	99	90.338	Pelodiscus_sinensis
ENSG00000126524	SBDS	97	89.157	ENSPMGG00000004246	sbds	100	81.928	Periophthalmus_magnuspinnatus
ENSG00000126524	SBDS	100	97.200	ENSPEMG00000008728	Sbds	100	97.200	Peromyscus_maniculatus_bairdii
ENSG00000126524	SBDS	97	98.795	ENSPCIG00000029718	SBDS	100	95.200	Phascolarctos_cinereus
ENSG00000126524	SBDS	97	87.952	ENSPFOG00000015837	sbds	100	80.723	Poecilia_formosa
ENSG00000126524	SBDS	97	87.952	ENSPLAG00000003641	sbds	100	80.723	Poecilia_latipinna
ENSG00000126524	SBDS	97	87.952	ENSPMEG00000019483	sbds	100	80.723	Poecilia_mexicana
ENSG00000126524	SBDS	97	87.952	ENSPREG00000018758	sbds	100	80.321	Poecilia_reticulata
ENSG00000126524	SBDS	100	100.000	ENSPPYG00000017513	SBDS	100	100.000	Pongo_abelii
ENSG00000126524	SBDS	100	98.800	ENSPCOG00000021098	SBDS	100	98.800	Propithecus_coquereli
ENSG00000126524	SBDS	100	99.200	ENSPVAG00000009369	SBDS	100	99.200	Pteropus_vampyrus
ENSG00000126524	SBDS	97	89.157	ENSPNYG00000022403	sbds	100	83.534	Pundamilia_nyererei
ENSG00000126524	SBDS	100	85.200	ENSPNAG00000001120	sbds	100	85.200	Pygocentrus_nattereri
ENSG00000126524	SBDS	100	97.200	ENSRNOG00000000888	Sbds	100	97.200	Rattus_norvegicus
ENSG00000126524	SBDS	100	80.233	ENSRBIG00000041549	-	68	80.233	Rhinopithecus_bieti
ENSG00000126524	SBDS	100	100.000	ENSRBIG00000035557	SBDS	100	100.000	Rhinopithecus_bieti
ENSG00000126524	SBDS	100	90.698	ENSRROG00000041986	-	100	80.000	Rhinopithecus_roxellana
ENSG00000126524	SBDS	100	100.000	ENSRROG00000040842	-	100	100.000	Rhinopithecus_roxellana
ENSG00000126524	SBDS	90	66.234	YLR022C	-	96	43.320	Saccharomyces_cerevisiae
ENSG00000126524	SBDS	93	99.138	ENSSBOG00000022460	SBDS	100	99.138	Saimiri_boliviensis_boliviensis
ENSG00000126524	SBDS	100	83.200	ENSSHAG00000010263	SBDS	100	83.200	Sarcophilus_harrisii
ENSG00000126524	SBDS	100	85.600	ENSSFOG00015001108	sbds	100	85.600	Scleropages_formosus
ENSG00000126524	SBDS	97	87.952	ENSSMAG00000020506	sbds	100	83.936	Scophthalmus_maximus
ENSG00000126524	SBDS	97	89.157	ENSSDUG00000001528	sbds	100	82.731	Seriola_dumerili
ENSG00000126524	SBDS	97	89.157	ENSSLDG00000003659	sbds	100	83.133	Seriola_lalandi_dorsalis
ENSG00000126524	SBDS	97	98.795	ENSSARG00000001899	-	73	98.837	Sorex_araneus
ENSG00000126524	SBDS	97	98.795	ENSSARG00000013132	-	100	98.693	Sorex_araneus
ENSG00000126524	SBDS	100	86.800	ENSSPUG00000002699	SBDS	100	86.800	Sphenodon_punctatus
ENSG00000126524	SBDS	97	89.157	ENSSPAG00000016419	sbds	100	75.600	Stegastes_partitus
ENSG00000126524	SBDS	100	99.200	ENSSSCG00000007732	SBDS	100	99.200	Sus_scrofa
ENSG00000126524	SBDS	66	89.091	ENSTGUG00000003426	SBDS	99	89.091	Taeniopygia_guttata
ENSG00000126524	SBDS	97	89.157	ENSTRUG00000021443	sbds	100	83.133	Takifugu_rubripes
ENSG00000126524	SBDS	97	86.747	ENSTNIG00000019000	sbds	100	81.928	Tetraodon_nigroviridis
ENSG00000126524	SBDS	97	97.590	ENSTBEG00000001178	SBDS	100	84.135	Tupaia_belangeri
ENSG00000126524	SBDS	97	100.000	ENSTTRG00000003921	SBDS	100	79.200	Tursiops_truncatus
ENSG00000126524	SBDS	100	98.800	ENSUAMG00000001326	SBDS	100	98.800	Ursus_americanus
ENSG00000126524	SBDS	100	98.800	ENSUMAG00000015353	SBDS	100	98.800	Ursus_maritimus
ENSG00000126524	SBDS	100	99.200	ENSVVUG00000016478	SBDS	100	99.200	Vulpes_vulpes
ENSG00000126524	SBDS	100	86.400	ENSXETG00000010093	sbds	100	86.400	Xenopus_tropicalis
ENSG00000126524	SBDS	97	87.952	ENSXCOG00000010639	sbds	100	73.494	Xiphophorus_couchianus
ENSG00000126524	SBDS	97	87.952	ENSXMAG00000006065	sbds	100	81.124	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000922	spindle pole	18324336.19759903.	IDA	Component
GO:0001833	inner cell mass cell proliferation	-	IEA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	17475909.17643419.21044950.26871637.	IPI	Function
GO:0005634	nucleus	15860664.18324336.	IDA	Component
GO:0005654	nucleoplasm	-	IEA	Component
GO:0005730	nucleolus	15860664.17475909.	IDA	Component
GO:0005737	cytoplasm	15860664.18324336.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006364	rRNA processing	17643419.	IMP	Process
GO:0007052	mitotic spindle organization	18324336.	IDA	Process
GO:0008017	microtubule binding	18324336.	IDA	Function
GO:0008283	cell proliferation	19759903.	IMP	Process
GO:0019843	rRNA binding	17475909.	IDA	Function
GO:0030282	bone mineralization	17920346.	IMP	Process
GO:0030595	leukocyte chemotaxis	14743349.	IDA	Process
GO:0042256	mature ribosome assembly	21536732.	IDA	Process
GO:0043022	ribosome binding	21536732.	IDA	Function
GO:0048539	bone marrow development	15342903.	IMP	Process

Cancer associated literatures

Show entries

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PID	Title	Article	Time	Author	Doi
20979173	SBDS-deficiency results in deregulation of reactive oxygen species leading to increased cell death and decreased cell growth.	Pediatr Blood Cancer	2010 Dec 1	Ambekar C	doi: 10.1002/pbc.22700.

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Differential Expression

Expression in 33 cancers

Mutations

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Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
STAD	chr7	66988255	3'UTR	novel		0.22
COAD	chr7	66988304	3'UTR	novel		0.37
COAD	chr7	66988319	3'UTR	novel		0.38
COAD	chr7	66988328	3'UTR	rs761617920		0.31
ESCA	chr7	66988351	3'UTR	novel		0.17
LUSC	chr7	66988407	Silent	novel	L239L	0.33
CESC	chr7	66988411	Missense_Mutation	rs747312896	N238S	0.36
UCEC	chr7	66988426	Missense_Mutation	rs796954165	S233Y	0.34
BLCA	chr7	66988444	Missense_Mutation	NA	E227G	0.26
UCEC	chr7	66988447	Frame_Shift_Del	novel	*K226Rfs14**	0.49

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Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.0833	0.067545
HNSC	DEL	0.0632	0.22646
LUAD	DEL	0.0736	0.0059643
LUSC	DEL	0.0679	0.038823
PAAD	DEL	0.0109	0.0030251
PRAD	AMP	0.1362	0.016187
SKCM	DEL	0.0381	0.00079981
TGCT	AMP	0.72	0.035574
THCA	DEL	0	0.27619

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0011	Kaplan-Meier Survival Analysis
STAD	0.032	Kaplan-Meier Survival Analysis
SARC	0.0052	Kaplan-Meier Survival Analysis
HNSC	0.0012	Kaplan-Meier Survival Analysis
SKCM	0.031	Kaplan-Meier Survival Analysis
BRCA	0.048	Kaplan-Meier Survival Analysis
PAAD	0.034	Kaplan-Meier Survival Analysis
BLCA	0.0032	Kaplan-Meier Survival Analysis
CESC	0.042	Kaplan-Meier Survival Analysis
UCEC	0.00062	Kaplan-Meier Survival Analysis
LGG	0.04	Kaplan-Meier Survival Analysis
CHOL	0.035	Kaplan-Meier Survival Analysis
LUAD	0.0093	Kaplan-Meier Survival Analysis