EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000126749 (Gene tree)
Gene ID: 10436
Gene Symbol: EMG1
Alias: C2F|NEP1|Grcc2f
Full Name: EMG1 N1-specific pseudouridine methyltransferase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 26,648 bases
Position: chr12:6,970,781-6,997,428
Accession: 16912
RBP type: canonical RBP
Summary: This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000470560	EMG1	PF03587.14	9.5e-84	1	1
ENSP00000479546	EMG1	PF03587.14	3.3e-62	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21087996	Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.	Nucleic Acids Res	2011 Mar	Thomas SR	doi: 10.1093/nar/gkq1131
20047967	The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.	Nucleic Acids Res	2010 Apr	Wurm JP	doi: 10.1093/nar/gkp1189
18063569	The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases.	Nucleic Acids Res	2008 Feb	Leulliot N	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000607161	EMG1-204	1087	-	ENSP00000480420	223 (aa)	-	A0A087WWQ2
ENST00000539196	EMG1-202	616	-	ENSP00000479546	149 (aa)	-	A0A087WVM7
ENST00000261406	EMG1-201	958	-	ENSP00000476966	217 (aa)	-	V9GYP5
ENST00000599672	EMG1-203	4898	-	ENSP00000470560	244 (aa)	-	Q92979
ENST00000611981	EMG1-205	1223	-	-	- (aa)	-	-
ENST00000620255	EMG1-206	720	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000126749's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000126749	rs12580543	12	6992881	C	Red blood cell fatty acid levels	25500335	[NR] unit increase	0.21	EFO_0005110\|EFO_0006807
ENSG00000126749	rs12579775	12	6976009	A	Oleic acid (18:1n-9) levels	28298293	[0.35-0.73] unit decrease	0.539	EFO_0006810

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000126749's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000126749	EMG1	95	68.240	ENSAPOG00000023213	emg1	98	68.240	Acanthochromis_polyacanthus
ENSG00000126749	EMG1	100	93.443	ENSAMEG00000013753	EMG1	100	93.443	Ailuropoda_melanoleuca
ENSG00000126749	EMG1	95	68.670	ENSACIG00000011786	emg1	97	68.670	Amphilophus_citrinellus
ENSG00000126749	EMG1	95	72.028	ENSAOCG00000006520	emg1	95	68.670	Amphiprion_ocellaris
ENSG00000126749	EMG1	95	68.670	ENSAPEG00000011094	emg1	95	68.670	Amphiprion_percula
ENSG00000126749	EMG1	100	69.672	ENSATEG00000021642	emg1	100	69.672	Anabas_testudineus
ENSG00000126749	EMG1	77	84.127	ENSAPLG00000005308	EMG1	100	84.127	Anas_platyrhynchos
ENSG00000126749	EMG1	89	80.717	ENSACAG00000007210	EMG1	97	80.717	Anolis_carolinensis
ENSG00000126749	EMG1	100	87.705	ENSANAG00000029536	-	100	87.705	Aotus_nancymaae
ENSG00000126749	EMG1	100	95.918	ENSANAG00000022855	-	100	95.918	Aotus_nancymaae
ENSG00000126749	EMG1	95	69.099	ENSACLG00000023688	emg1	97	69.099	Astatotilapia_calliptera
ENSG00000126749	EMG1	95	68.670	ENSAMXG00000018994	emg1	97	68.670	Astyanax_mexicanus
ENSG00000126749	EMG1	100	91.803	ENSBTAG00000013126	EMG1	70	91.803	Bos_taurus
ENSG00000126749	EMG1	93	54.783	WBGene00012652	Y39A1A.14	99	54.783	Caenorhabditis_elegans
ENSG00000126749	EMG1	100	95.902	ENSCJAG00000007120	EMG1	100	95.902	Callithrix_jacchus
ENSG00000126749	EMG1	100	94.262	ENSCAFG00000014424	EMG1	100	94.262	Canis_familiaris
ENSG00000126749	EMG1	100	94.262	ENSCAFG00020003127	EMG1	100	94.262	Canis_lupus_dingo
ENSG00000126749	EMG1	100	92.213	ENSCHIG00000003188	EMG1	100	92.213	Capra_hircus
ENSG00000126749	EMG1	62	95.364	ENSTSYG00000035847	EMG1	100	95.364	Carlito_syrichta
ENSG00000126749	EMG1	62	97.351	ENSCAPG00000011212	EMG1	100	97.351	Cavia_aperea
ENSG00000126749	EMG1	100	91.803	ENSCPOG00000025388	EMG1	100	91.803	Cavia_porcellus
ENSG00000126749	EMG1	100	97.131	ENSCCAG00000033309	-	100	97.131	Cebus_capucinus
ENSG00000126749	EMG1	60	73.288	ENSCCAG00000034889	-	85	73.288	Cebus_capucinus
ENSG00000126749	EMG1	62	70.395	ENSCCAG00000024274	-	100	70.395	Cebus_capucinus
ENSG00000126749	EMG1	100	98.361	ENSCATG00000016750	EMG1	100	98.361	Cercocebus_atys
ENSG00000126749	EMG1	100	91.393	ENSCLAG00000015067	EMG1	100	91.393	Chinchilla_lanigera
ENSG00000126749	EMG1	100	98.361	ENSCSAG00000010140	EMG1	100	98.361	Chlorocebus_sabaeus
ENSG00000126749	EMG1	100	92.623	ENSCHOG00000002886	EMG1	100	92.623	Choloepus_hoffmanni
ENSG00000126749	EMG1	75	96.429	ENSCPBG00000005167	EMG1	69	76.667	Chrysemys_picta_bellii
ENSG00000126749	EMG1	86	74.762	ENSCING00000022202	-	89	74.762	Ciona_intestinalis
ENSG00000126749	EMG1	84	75.980	ENSCSAVG00000005612	-	86	75.980	Ciona_savignyi
ENSG00000126749	EMG1	93	87.225	ENSCANG00000042498	-	100	93.571	Colobus_angolensis_palliatus
ENSG00000126749	EMG1	100	97.541	ENSCANG00000043101	-	100	97.541	Colobus_angolensis_palliatus
ENSG00000126749	EMG1	100	90.984	ENSCGRG00001018228	Emg1	100	90.984	Cricetulus_griseus_chok1gshd
ENSG00000126749	EMG1	100	90.984	ENSCGRG00000018238	Emg1	100	90.984	Cricetulus_griseus_crigri
ENSG00000126749	EMG1	100	65.587	ENSCSEG00000020136	emg1	100	65.587	Cynoglossus_semilaevis
ENSG00000126749	EMG1	95	68.966	ENSCVAG00000001164	emg1	98	68.966	Cyprinodon_variegatus
ENSG00000126749	EMG1	95	67.382	ENSDARG00000056914	emg1	97	67.382	Danio_rerio
ENSG00000126749	EMG1	100	92.213	ENSDNOG00000005533	EMG1	100	92.213	Dasypus_novemcinctus
ENSG00000126749	EMG1	100	77.869	ENSDORG00000009795	Emg1	100	77.869	Dipodomys_ordii
ENSG00000126749	EMG1	99	50.485	FBgn0029714	CG3527	84	63.679	Drosophila_melanogaster
ENSG00000126749	EMG1	56	92.105	ENSETEG00000009111	-	99	63.816	Echinops_telfairi
ENSG00000126749	EMG1	89	68.037	ENSEBUG00000008287	emg1	84	68.037	Eptatretus_burgeri
ENSG00000126749	EMG1	100	93.443	ENSEASG00005016018	EMG1	100	93.443	Equus_asinus_asinus
ENSG00000126749	EMG1	100	93.852	ENSECAG00000022412	EMG1	100	93.852	Equus_caballus
ENSG00000126749	EMG1	100	92.213	ENSEEUG00000000065	EMG1	100	92.213	Erinaceus_europaeus
ENSG00000126749	EMG1	100	93.033	ENSFCAG00000004288	EMG1	100	93.033	Felis_catus
ENSG00000126749	EMG1	84	87.864	ENSFALG00000004617	EMG1	93	81.659	Ficedula_albicollis
ENSG00000126749	EMG1	100	92.213	ENSFDAG00000011086	EMG1	100	92.213	Fukomys_damarensis
ENSG00000126749	EMG1	64	83.158	ENSFHEG00000014379	emg1	63	67.143	Fundulus_heteroclitus
ENSG00000126749	EMG1	57	60.870	ENSFHEG00000014307	emg1	82	60.870	Fundulus_heteroclitus
ENSG00000126749	EMG1	95	66.524	ENSGMOG00000011025	emg1	95	66.524	Gadus_morhua
ENSG00000126749	EMG1	100	78.279	ENSGALG00000014568	EMG1	100	78.279	Gallus_gallus
ENSG00000126749	EMG1	95	69.099	ENSGAFG00000014143	emg1	98	69.099	Gambusia_affinis
ENSG00000126749	EMG1	100	67.347	ENSGACG00000010330	emg1	98	67.347	Gasterosteus_aculeatus
ENSG00000126749	EMG1	77	87.302	ENSGAGG00000005641	EMG1	100	86.755	Gopherus_agassizii
ENSG00000126749	EMG1	100	98.770	ENSGGOG00000004287	EMG1	100	98.770	Gorilla_gorilla
ENSG00000126749	EMG1	95	72.727	ENSHBUG00000014862	emg1	97	69.099	Haplochromis_burtoni
ENSG00000126749	EMG1	100	91.463	ENSHGLG00000001300	EMG1	100	91.463	Heterocephalus_glaber_female
ENSG00000126749	EMG1	100	91.463	ENSHGLG00100011644	EMG1	100	91.463	Heterocephalus_glaber_male
ENSG00000126749	EMG1	99	66.942	ENSHCOG00000017870	emg1	99	66.942	Hippocampus_comes
ENSG00000126749	EMG1	95	71.528	ENSIPUG00000008261	emg1	97	69.099	Ictalurus_punctatus
ENSG00000126749	EMG1	100	92.213	ENSSTOG00000000387	EMG1	100	92.213	Ictidomys_tridecemlineatus
ENSG00000126749	EMG1	100	89.837	ENSJJAG00000018448	Emg1	100	89.837	Jaculus_jaculus
ENSG00000126749	EMG1	100	67.213	ENSKMAG00000007069	emg1	100	67.213	Kryptolebias_marmoratus
ENSG00000126749	EMG1	100	68.852	ENSLBEG00000007424	emg1	100	68.852	Labrus_bergylta
ENSG00000126749	EMG1	95	69.099	ENSLOCG00000008451	emg1	95	69.099	Lepisosteus_oculatus
ENSG00000126749	EMG1	100	92.213	ENSLAFG00000001314	EMG1	100	92.213	Loxodonta_africana
ENSG00000126749	EMG1	100	98.361	ENSMFAG00000037142	EMG1	100	98.361	Macaca_fascicularis
ENSG00000126749	EMG1	100	98.361	ENSMMUG00000010207	EMG1	100	98.361	Macaca_mulatta
ENSG00000126749	EMG1	100	98.361	ENSMNEG00000040907	EMG1	100	98.361	Macaca_nemestrina
ENSG00000126749	EMG1	100	97.951	ENSMLEG00000026029	EMG1	100	97.951	Mandrillus_leucophaeus
ENSG00000126749	EMG1	100	70.082	ENSMAMG00000001888	emg1	100	70.082	Mastacembelus_armatus
ENSG00000126749	EMG1	95	69.099	ENSMZEG00005017546	emg1	97	69.099	Maylandia_zebra
ENSG00000126749	EMG1	84	86.408	ENSMGAG00000014145	EMG1	98	77.049	Meleagris_gallopavo
ENSG00000126749	EMG1	100	91.393	ENSMAUG00000011093	Emg1	100	91.393	Mesocricetus_auratus
ENSG00000126749	EMG1	100	93.852	ENSMICG00000001790	EMG1	100	93.852	Microcebus_murinus
ENSG00000126749	EMG1	100	92.213	ENSMOCG00000022570	Emg1	100	92.213	Microtus_ochrogaster
ENSG00000126749	EMG1	95	67.382	ENSMMOG00000016090	emg1	97	67.382	Mola_mola
ENSG00000126749	EMG1	100	86.885	ENSMODG00000018161	EMG1	98	86.885	Monodelphis_domestica
ENSG00000126749	EMG1	95	69.528	ENSMALG00000022477	emg1	97	69.528	Monopterus_albus
ENSG00000126749	EMG1	100	89.754	MGP_CAROLIEiJ_G0028844	Emg1	100	89.754	Mus_caroli
ENSG00000126749	EMG1	100	88.934	ENSMUSG00000004268	Emg1	100	88.934	Mus_musculus
ENSG00000126749	EMG1	100	89.344	MGP_PahariEiJ_G0022605	Emg1	100	89.344	Mus_pahari
ENSG00000126749	EMG1	100	89.344	MGP_SPRETEiJ_G0029886	Emg1	100	89.344	Mus_spretus
ENSG00000126749	EMG1	100	93.443	ENSMPUG00000016763	EMG1	100	93.443	Mustela_putorius_furo
ENSG00000126749	EMG1	100	91.463	ENSMLUG00000009196	EMG1	100	91.463	Myotis_lucifugus
ENSG00000126749	EMG1	100	90.984	ENSNGAG00000022592	Emg1	100	90.984	Nannospalax_galili
ENSG00000126749	EMG1	95	69.099	ENSNBRG00000001192	emg1	97	69.099	Neolamprologus_brichardi
ENSG00000126749	EMG1	100	97.541	ENSNLEG00000005080	EMG1	100	97.541	Nomascus_leucogenys
ENSG00000126749	EMG1	95	85.849	ENSMEUG00000000831	EMG1	100	87.225	Notamacropus_eugenii
ENSG00000126749	EMG1	74	96.396	ENSOPRG00000004071	-	100	87.421	Ochotona_princeps
ENSG00000126749	EMG1	77	93.617	ENSOPRG00000016878	-	100	93.617	Ochotona_princeps
ENSG00000126749	EMG1	100	90.164	ENSODEG00000004059	EMG1	100	90.164	Octodon_degus
ENSG00000126749	EMG1	95	69.099	ENSONIG00000012893	emg1	97	69.099	Oreochromis_niloticus
ENSG00000126749	EMG1	100	91.393	ENSOCUG00000003603	EMG1	100	91.393	Oryctolagus_cuniculus
ENSG00000126749	EMG1	95	69.957	ENSORLG00000012146	emg1	94	69.957	Oryzias_latipes
ENSG00000126749	EMG1	95	69.957	ENSORLG00020005499	emg1	97	69.957	Oryzias_latipes_hni
ENSG00000126749	EMG1	95	69.957	ENSORLG00015011535	emg1	97	69.957	Oryzias_latipes_hsok
ENSG00000126749	EMG1	95	70.815	ENSOMEG00000012687	emg1	97	70.815	Oryzias_melastigma
ENSG00000126749	EMG1	100	93.443	ENSOGAG00000006975	EMG1	100	93.443	Otolemur_garnettii
ENSG00000126749	EMG1	100	91.057	ENSOARG00000004923	EMG1	100	91.057	Ovis_aries
ENSG00000126749	EMG1	100	99.180	ENSPPAG00000033046	EMG1	100	99.180	Pan_paniscus
ENSG00000126749	EMG1	100	93.443	ENSPPRG00000012350	EMG1	100	93.443	Panthera_pardus
ENSG00000126749	EMG1	100	93.443	ENSPTIG00000000358	EMG1	100	93.443	Panthera_tigris_altaica
ENSG00000126749	EMG1	100	99.180	ENSPTRG00000048050	EMG1	100	99.180	Pan_troglodytes
ENSG00000126749	EMG1	100	97.951	ENSPANG00000019398	-	100	97.951	Papio_anubis
ENSG00000126749	EMG1	100	97.541	ENSPANG00000005523	-	100	97.541	Papio_anubis
ENSG00000126749	EMG1	100	66.531	ENSPKIG00000025303	emg1	100	66.531	Paramormyrops_kingsleyae
ENSG00000126749	EMG1	100	76.735	ENSPSIG00000011094	EMG1	100	76.735	Pelodiscus_sinensis
ENSG00000126749	EMG1	95	69.957	ENSPMGG00000019918	emg1	98	69.957	Periophthalmus_magnuspinnatus
ENSG00000126749	EMG1	100	91.393	ENSPEMG00000010244	Emg1	100	91.393	Peromyscus_maniculatus_bairdii
ENSG00000126749	EMG1	100	89.754	ENSPCIG00000002814	EMG1	100	89.754	Phascolarctos_cinereus
ENSG00000126749	EMG1	95	68.240	ENSPFOG00000013034	emg1	98	68.240	Poecilia_formosa
ENSG00000126749	EMG1	95	68.240	ENSPLAG00000000125	emg1	98	68.240	Poecilia_latipinna
ENSG00000126749	EMG1	95	68.670	ENSPMEG00000016802	emg1	98	68.670	Poecilia_mexicana
ENSG00000126749	EMG1	95	67.811	ENSPREG00000010409	emg1	80	67.811	Poecilia_reticulata
ENSG00000126749	EMG1	100	98.770	ENSPPYG00000004215	EMG1	100	98.770	Pongo_abelii
ENSG00000126749	EMG1	100	79.918	ENSPCAG00000012368	EMG1	100	79.918	Procavia_capensis
ENSG00000126749	EMG1	100	95.082	ENSPCOG00000028560	EMG1	100	95.082	Propithecus_coquereli
ENSG00000126749	EMG1	100	93.852	ENSPVAG00000006030	EMG1	100	93.852	Pteropus_vampyrus
ENSG00000126749	EMG1	95	69.099	ENSPNYG00000023172	emg1	97	69.099	Pundamilia_nyererei
ENSG00000126749	EMG1	95	67.382	ENSPNAG00000019953	emg1	97	67.382	Pygocentrus_nattereri
ENSG00000126749	EMG1	100	90.984	ENSRNOG00000012828	Emg1	100	90.984	Rattus_norvegicus
ENSG00000126749	EMG1	100	97.951	ENSRBIG00000031315	EMG1	100	97.951	Rhinopithecus_bieti
ENSG00000126749	EMG1	100	97.951	ENSRROG00000032961	EMG1	100	97.951	Rhinopithecus_roxellana
ENSG00000126749	EMG1	95	51.240	YLR186W	EMG1	96	51.240	Saccharomyces_cerevisiae
ENSG00000126749	EMG1	100	96.721	ENSSBOG00000029143	-	100	96.721	Saimiri_boliviensis_boliviensis
ENSG00000126749	EMG1	99	66.805	ENSSBOG00000022895	-	98	66.805	Saimiri_boliviensis_boliviensis
ENSG00000126749	EMG1	100	87.705	ENSSHAG00000016428	EMG1	100	87.705	Sarcophilus_harrisii
ENSG00000126749	EMG1	99	67.333	ENSSFOG00015002421	emg1	97	68.511	Scleropages_formosus
ENSG00000126749	EMG1	95	69.957	ENSSMAG00000011806	emg1	97	69.957	Scophthalmus_maximus
ENSG00000126749	EMG1	100	67.623	ENSSDUG00000011345	emg1	95	67.623	Seriola_dumerili
ENSG00000126749	EMG1	100	67.623	ENSSLDG00000023439	emg1	95	67.623	Seriola_lalandi_dorsalis
ENSG00000126749	EMG1	100	70.492	ENSSARG00000002227	EMG1	100	70.492	Sorex_araneus
ENSG00000126749	EMG1	100	75.102	ENSSPUG00000014446	EMG1	100	75.102	Sphenodon_punctatus
ENSG00000126749	EMG1	95	69.397	ENSSPAG00000005460	emg1	98	69.397	Stegastes_partitus
ENSG00000126749	EMG1	100	92.623	ENSSSCG00000026812	EMG1	100	92.623	Sus_scrofa
ENSG00000126749	EMG1	84	88.350	ENSTGUG00000013271	EMG1	100	88.350	Taeniopygia_guttata
ENSG00000126749	EMG1	95	70.386	ENSTRUG00000001906	emg1	97	70.386	Takifugu_rubripes
ENSG00000126749	EMG1	100	68.033	ENSTNIG00000008047	emg1	98	68.033	Tetraodon_nigroviridis
ENSG00000126749	EMG1	86	94.737	ENSTBEG00000015406	EMG1	100	94.737	Tupaia_belangeri
ENSG00000126749	EMG1	100	76.639	ENSTTRG00000004810	EMG1	100	76.639	Tursiops_truncatus
ENSG00000126749	EMG1	100	93.852	ENSUAMG00000026959	EMG1	100	93.852	Ursus_americanus
ENSG00000126749	EMG1	100	93.443	ENSUMAG00000003248	EMG1	100	93.443	Ursus_maritimus
ENSG00000126749	EMG1	100	93.852	ENSVVUG00000010807	EMG1	100	93.852	Vulpes_vulpes
ENSG00000126749	EMG1	99	65.482	ENSXETG00000023917	emg1	99	81.281	Xenopus_tropicalis
ENSG00000126749	EMG1	95	68.240	ENSXMAG00000011508	emg1	98	68.240	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001824	blastocyst development	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	-	ISS	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005730	nucleolus	-	ISS	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0006364	rRNA processing	-	ISS	Process
GO:0006364	rRNA processing	-	TAS	Process
GO:0017126	nucleologenesis	-	IEA	Process
GO:0019843	rRNA binding	21873635.	IBA	Function
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0042274	ribosomal small subunit biogenesis	-	ISS	Process
GO:0070037	rRNA (pseudouridine) methyltransferase activity	21873635.	IBA	Function
GO:0070037	rRNA (pseudouridine) methyltransferase activity	20047967.	IDA	Function
GO:0070475	rRNA base methylation	21873635.	IBA	Process