EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000128595 (Gene tree)
Gene ID: 813
Gene Symbol: CALU
Alias: N
Full Name: calumenin
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 34,132 bases
Position: chr7:128,739,292-128,773,423
Accession: 1458
RBP type: non-canonical RBP
Summary: The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000479257	CALU-203	2572	-	ENSP00000420381	323 (aa)	-	O43852
ENST00000542996	CALU-206	4225	-	ENSP00000438248	323 (aa)	-	O43852
ENST00000535011	CALU-205	3210	-	ENSP00000442110	224 (aa)	-	O43852
ENST00000249364	CALU-201	3357	-	ENSP00000249364	315 (aa)	-	O43852
ENST00000493278	CALU-204	589	XM_017012659	ENSP00000417973	147 (aa)	XP_016868148	H0Y875
ENST00000449187	CALU-202	2438	-	ENSP00000408838	315 (aa)	-	O43852

Gene Model

Click here to download ENSG00000128595's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000128595	Blood Pressure	4.7091678E-005	-
ENSG00000128595	Education	7E-9	27225129

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000128595	rs113520408	7	128762728	A	Educational attainment (years of education)	27225129	NR unit increase	0.014647213	EFO_0004784
ENSG00000128595	rs1043595	7	128769958	A	Intelligence (MTAG)	29326435	[0.014-0.027] unit increase	0.02060705	EFO_0004337
ENSG00000128595	rs1043595	7	128769958	A	Cognitive performance	30038396	[0.015-0.027] unit increase	0.021	EFO_0008354
ENSG00000128595	rs113520408	7	128762728	A	Educational attainment (MTAG)	30038396	[0.013-0.019] unit increase	0.0163	EFO_0004784
ENSG00000128595	rs113520408	7	128762728	G	Self-reported math ability	30038396	[0.013-0.022] unit decrease	0.0176	EFO_0004875
ENSG00000128595	rs4559164	7	128761756	G	Highest math class taken	30038396	[0.011-0.02] unit decrease	0.0155	EFO_0004875
ENSG00000128595	rs113520408	7	128762728	A	Self-reported math ability (MTAG)	30038396	[0.016-0.024] unit increase	0.0197	EFO_0004875
ENSG00000128595	rs113520408	7	128762728	A	Highest math class taken (MTAG)	30038396	[0.017-0.024] unit increase	0.0207	EFO_0004875
ENSG00000128595	rs1043595	7	128769958	G	Moderate to vigorous physical activity levels	29899525	unit increase	0.014	EFO_0008002
ENSG00000128595	rs1043595	7	128769958	A	Cognitive performance (MTAG)	30038396	[0.02-0.03] unit increase	0.0252	EFO_0008354
ENSG00000128595	rs1043595	7	128769958	A	Intelligence	29942086	z-score increase	6.071	EFO_0004337
ENSG00000128595	rs113520408	7	128762728	A	Educational attainment (years of education)	30038396	[0.012-0.019] unit increase	0.0155	EFO_0004784
ENSG00000128595	rs339099	7	128756291	T	Educational attainment (years of education)	30038396	[0.01-0.0154] unit decrease	0.0127	EFO_0004784
ENSG00000128595	rs339095	7	128765993	G	Alcohol consumption (drinks per week) (MTAG)	30643251	[0.0049-0.01] unit decrease	0.00744603	EFO_0007878

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000128595's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005509	calcium ion binding	21873635.	IBA	Function
GO:0005509	calcium ion binding	10094503.	IDA	Function
GO:0005515	protein binding	18688696.25416956.	IPI	Function
GO:0005576	extracellular region	-	IEA	Component
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	-	IDA	Component
GO:0005788	endoplasmic reticulum lumen	-	TAS	Component
GO:0005789	endoplasmic reticulum membrane	-	IEA	Component
GO:0005794	Golgi apparatus	-	IEA	Component
GO:0008150	biological_process	-	ND	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0033018	sarcoplasmic reticulum lumen	-	IEA	Component
GO:0042470	melanosome	-	IEA	Component
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0044267	cellular protein metabolic process	-	TAS	Process