EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000130119 (Gene tree)
Gene ID: 54552
Gene Symbol: GNL3L
Alias: FLJ10613|GNL3B
Full Name: G protein nucleolar 3 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 91,355 bases
Position: chrX:54,530,211-54,621,565
Accession: 25553
RBP type: canonical RBP
Summary: The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000338573	MMR_HSR1	PF01926.23	3e-15	1	1
ENSP00000354091	MMR_HSR1	PF01926.23	3e-15	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000336470	GNL3L-201	2357	-	ENSP00000338573	582 (aa)	-	Q9NVN8
ENST00000489691	GNL3L-203	895	-	-	- (aa)	-	-
ENST00000360845	GNL3L-202	2135	-	ENSP00000354091	582 (aa)	-	Q9NVN8

Gene Model

Click here to download ENSG00000130119's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000130119's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000130119	GNL3L	56	33.234	ENSG00000134697	GNL2	99	31.602
ENSG00000130119	GNL3L	71	38.647	ENSG00000163938	GNL3	83	33.036

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130119	GNL3L	90	49.907	ENSAPOG00000012629	gnl3l	92	50.280	Acanthochromis_polyacanthus
ENSG00000130119	GNL3L	99	92.535	ENSAMEG00000002528	GNL3L	99	92.535	Ailuropoda_melanoleuca
ENSG00000130119	GNL3L	88	48.956	ENSACIG00000010900	gnl3l	95	48.956	Amphilophus_citrinellus
ENSG00000130119	GNL3L	90	50.841	ENSAOCG00000020369	gnl3l	92	50.841	Amphiprion_ocellaris
ENSG00000130119	GNL3L	90	50.841	ENSAPEG00000023280	gnl3l	92	50.841	Amphiprion_percula
ENSG00000130119	GNL3L	89	50.844	ENSATEG00000009762	gnl3l	91	50.844	Anabas_testudineus
ENSG00000130119	GNL3L	94	50.808	ENSACAG00000012525	GNL3L	99	51.557	Anolis_carolinensis
ENSG00000130119	GNL3L	99	94.320	ENSANAG00000023117	-	100	94.320	Aotus_nancymaae
ENSG00000130119	GNL3L	100	72.165	ENSANAG00000022057	-	100	72.852	Aotus_nancymaae
ENSG00000130119	GNL3L	93	49.365	ENSACLG00000021244	gnl3l	95	49.365	Astatotilapia_calliptera
ENSG00000130119	GNL3L	89	51.412	ENSAMXG00000006376	gnl3l	90	51.412	Astyanax_mexicanus
ENSG00000130119	GNL3L	100	91.581	ENSBTAG00000031564	GNL3L	100	91.581	Bos_taurus
ENSG00000130119	GNL3L	100	92.955	ENSCJAG00000000252	GNL3L	100	92.955	Callithrix_jacchus
ENSG00000130119	GNL3L	100	90.550	ENSCAFG00000016455	GNL3L	89	90.550	Canis_familiaris
ENSG00000130119	GNL3L	100	90.550	ENSCAFG00020013979	GNL3L	89	90.550	Canis_lupus_dingo
ENSG00000130119	GNL3L	100	91.581	ENSTSYG00000004110	GNL3L	100	91.581	Carlito_syrichta
ENSG00000130119	GNL3L	99	84.364	ENSCPOG00000015617	GNL3L	100	84.364	Cavia_porcellus
ENSG00000130119	GNL3L	98	91.608	ENSCCAG00000023052	GNL3L	99	91.608	Cebus_capucinus
ENSG00000130119	GNL3L	99	94.664	ENSCATG00000031729	GNL3L	99	94.664	Cercocebus_atys
ENSG00000130119	GNL3L	86	76.482	ENSCATG00000036833	-	95	76.482	Cercocebus_atys
ENSG00000130119	GNL3L	95	87.590	ENSCLAG00000003823	GNL3L	100	85.911	Chinchilla_lanigera
ENSG00000130119	GNL3L	81	98.517	ENSCSAG00000012324	GNL3L	100	98.517	Chlorocebus_sabaeus
ENSG00000130119	GNL3L	75	42.740	ENSCPBG00000017415	GNL3L	80	43.288	Chrysemys_picta_bellii
ENSG00000130119	GNL3L	99	96.392	ENSCANG00000035316	GNL3L	99	96.392	Colobus_angolensis_palliatus
ENSG00000130119	GNL3L	100	67.925	ENSCANG00000015664	-	100	67.925	Colobus_angolensis_palliatus
ENSG00000130119	GNL3L	100	89.365	ENSCGRG00001017459	Gnl3l	100	89.365	Cricetulus_griseus_chok1gshd
ENSG00000130119	GNL3L	100	89.365	ENSCGRG00000017708	Gnl3l	100	89.365	Cricetulus_griseus_crigri
ENSG00000130119	GNL3L	88	51.141	ENSCSEG00000011209	gnl3l	92	51.141	Cynoglossus_semilaevis
ENSG00000130119	GNL3L	93	50.182	ENSCVAG00000001161	gnl3l	96	49.910	Cyprinodon_variegatus
ENSG00000130119	GNL3L	98	48.475	ENSDARG00000020595	gnl3l	97	48.718	Danio_rerio
ENSG00000130119	GNL3L	99	85.172	ENSDNOG00000048230	GNL3L	100	88.389	Dasypus_novemcinctus
ENSG00000130119	GNL3L	96	84.192	ENSDORG00000029665	Gnl3l	97	84.192	Dipodomys_ordii
ENSG00000130119	GNL3L	99	72.806	ENSETEG00000019317	GNL3L	99	72.806	Echinops_telfairi
ENSG00000130119	GNL3L	61	42.500	ENSEBUG00000011390	gnl3l	99	40.960	Eptatretus_burgeri
ENSG00000130119	GNL3L	99	90.625	ENSEASG00005006957	GNL3L	100	93.217	Equus_asinus_asinus
ENSG00000130119	GNL3L	100	90.206	ENSECAG00000000035	GNL3L	100	90.206	Equus_caballus
ENSG00000130119	GNL3L	51	98.333	ENSEEUG00000010951	-	62	98.333	Erinaceus_europaeus
ENSG00000130119	GNL3L	90	50.000	ENSELUG00000004555	gnl3l	92	50.000	Esox_lucius
ENSG00000130119	GNL3L	100	91.237	ENSFCAG00000008699	GNL3L	81	91.237	Felis_catus
ENSG00000130119	GNL3L	100	87.822	ENSFDAG00000020122	GNL3L	99	87.822	Fukomys_damarensis
ENSG00000130119	GNL3L	92	49.355	ENSGMOG00000018085	gnl3l	94	49.355	Gadus_morhua
ENSG00000130119	GNL3L	88	51.158	ENSGAFG00000011132	gnl3l	91	50.851	Gambusia_affinis
ENSG00000130119	GNL3L	91	50.282	ENSGACG00000010320	gnl3l	100	45.821	Gasterosteus_aculeatus
ENSG00000130119	GNL3L	95	50.000	ENSGAGG00000008638	GNL3L	68	50.360	Gopherus_agassizii
ENSG00000130119	GNL3L	100	99.141	ENSGGOG00000007550	GNL3L	100	99.141	Gorilla_gorilla
ENSG00000130119	GNL3L	93	49.365	ENSHBUG00000014227	gnl3l	96	50.870	Haplochromis_burtoni
ENSG00000130119	GNL3L	100	87.307	ENSHGLG00000001778	GNL3L	100	87.307	Heterocephalus_glaber_female
ENSG00000130119	GNL3L	86	81.395	ENSHGLG00000010598	-	100	81.395	Heterocephalus_glaber_female
ENSG00000130119	GNL3L	99	79.514	ENSHGLG00100012564	-	100	79.514	Heterocephalus_glaber_male
ENSG00000130119	GNL3L	100	87.307	ENSHGLG00100000291	GNL3L	100	87.307	Heterocephalus_glaber_male
ENSG00000130119	GNL3L	89	48.803	ENSHCOG00000009877	gnl3l	93	49.905	Hippocampus_comes
ENSG00000130119	GNL3L	93	47.568	ENSIPUG00000015441	gnl3l	95	47.568	Ictalurus_punctatus
ENSG00000130119	GNL3L	100	92.110	ENSSTOG00000023157	GNL3L	100	92.110	Ictidomys_tridecemlineatus
ENSG00000130119	GNL3L	98	78.746	ENSJJAG00000011439	Gnl3l	98	78.746	Jaculus_jaculus
ENSG00000130119	GNL3L	90	50.000	ENSKMAG00000020874	gnl3l	93	50.000	Kryptolebias_marmoratus
ENSG00000130119	GNL3L	90	49.815	ENSLBEG00000005837	gnl3l	91	49.815	Labrus_bergylta
ENSG00000130119	GNL3L	90	49.815	ENSLBEG00000018256	gnl3l	91	49.815	Labrus_bergylta
ENSG00000130119	GNL3L	59	48.266	ENSLACG00000010188	GNL3L	100	48.266	Latimeria_chalumnae
ENSG00000130119	GNL3L	93	47.544	ENSLOCG00000014702	gnl3l	94	47.544	Lepisosteus_oculatus
ENSG00000130119	GNL3L	100	86.770	ENSLAFG00000016701	GNL3L	100	86.770	Loxodonta_africana
ENSG00000130119	GNL3L	100	72.696	ENSMFAG00000046065	-	100	72.696	Macaca_fascicularis
ENSG00000130119	GNL3L	99	97.246	ENSMFAG00000000499	GNL3L	99	97.246	Macaca_fascicularis
ENSG00000130119	GNL3L	100	96.741	ENSMMUG00000008231	GNL3L	100	96.741	Macaca_mulatta
ENSG00000130119	GNL3L	100	73.038	ENSMMUG00000044075	-	100	73.038	Macaca_mulatta
ENSG00000130119	GNL3L	100	72.696	ENSMNEG00000031230	-	100	72.696	Macaca_nemestrina
ENSG00000130119	GNL3L	99	97.246	ENSMNEG00000034813	GNL3L	100	97.246	Macaca_nemestrina
ENSG00000130119	GNL3L	100	72.184	ENSMLEG00000039011	-	100	72.184	Mandrillus_leucophaeus
ENSG00000130119	GNL3L	99	90.878	ENSMLEG00000029679	GNL3L	99	90.878	Mandrillus_leucophaeus
ENSG00000130119	GNL3L	88	49.716	ENSMAMG00000023332	gnl3l	96	49.716	Mastacembelus_armatus
ENSG00000130119	GNL3L	93	49.365	ENSMZEG00005010346	gnl3l	95	49.365	Maylandia_zebra
ENSG00000130119	GNL3L	100	87.671	ENSMAUG00000013958	Gnl3l	100	87.671	Mesocricetus_auratus
ENSG00000130119	GNL3L	100	92.784	ENSMICG00000010144	GNL3L	100	92.784	Microcebus_murinus
ENSG00000130119	GNL3L	100	83.219	ENSMOCG00000021622	Gnl3l	98	83.219	Microtus_ochrogaster
ENSG00000130119	GNL3L	89	53.861	ENSMODG00000016028	-	100	54.049	Monodelphis_domestica
ENSG00000130119	GNL3L	94	48.837	ENSMALG00000007353	gnl3l	95	48.837	Monopterus_albus
ENSG00000130119	GNL3L	100	86.644	MGP_CAROLIEiJ_G0033489	Gnl3l	100	86.644	Mus_caroli
ENSG00000130119	GNL3L	100	86.815	ENSMUSG00000025266	Gnl3l	100	86.815	Mus_musculus
ENSG00000130119	GNL3L	100	84.193	MGP_PahariEiJ_G0032028	Gnl3l	100	84.193	Mus_pahari
ENSG00000130119	GNL3L	100	86.815	MGP_SPRETEiJ_G0034659	Gnl3l	100	86.815	Mus_spretus
ENSG00000130119	GNL3L	99	91.869	ENSMPUG00000011421	GNL3L	100	91.869	Mustela_putorius_furo
ENSG00000130119	GNL3L	100	84.708	ENSMLUG00000008331	GNL3L	100	84.708	Myotis_lucifugus
ENSG00000130119	GNL3L	99	88.542	ENSNGAG00000005965	Gnl3l	94	88.542	Nannospalax_galili
ENSG00000130119	GNL3L	88	50.867	ENSNBRG00000023334	gnl3l	95	50.867	Neolamprologus_brichardi
ENSG00000130119	GNL3L	99	98.623	ENSNLEG00000016233	GNL3L	99	98.623	Nomascus_leucogenys
ENSG00000130119	GNL3L	100	78.253	ENSNLEG00000031593	-	100	78.253	Nomascus_leucogenys
ENSG00000130119	GNL3L	71	75.989	ENSOPRG00000002722	-	68	75.989	Ochotona_princeps
ENSG00000130119	GNL3L	98	83.333	ENSODEG00000000662	-	100	83.333	Octodon_degus
ENSG00000130119	GNL3L	91	86.174	ENSODEG00000007050	-	98	86.174	Octodon_degus
ENSG00000130119	GNL3L	95	82.194	ENSODEG00000010311	-	100	80.617	Octodon_degus
ENSG00000130119	GNL3L	95	83.993	ENSODEG00000014878	-	100	82.333	Octodon_degus
ENSG00000130119	GNL3L	95	53.680	ENSOANG00000000700	-	97	54.496	Ornithorhynchus_anatinus
ENSG00000130119	GNL3L	100	89.519	ENSOCUG00000007408	GNL3L	100	89.519	Oryctolagus_cuniculus
ENSG00000130119	GNL3L	88	50.766	ENSORLG00000014117	gnl3l	90	50.766	Oryzias_latipes
ENSG00000130119	GNL3L	89	50.377	ENSORLG00020019295	gnl3l	91	50.377	Oryzias_latipes_hni
ENSG00000130119	GNL3L	89	51.048	ENSORLG00015014928	gnl3l	91	51.048	Oryzias_latipes_hsok
ENSG00000130119	GNL3L	89	51.336	ENSOMEG00000023685	gnl3l	91	51.336	Oryzias_melastigma
ENSG00000130119	GNL3L	99	89.391	ENSOGAG00000016754	GNL3L	100	89.391	Otolemur_garnettii
ENSG00000130119	GNL3L	76	86.848	ENSOARG00000021138	-	98	86.848	Ovis_aries
ENSG00000130119	GNL3L	94	72.678	ENSPPAG00000040301	-	99	72.678	Pan_paniscus
ENSG00000130119	GNL3L	100	99.656	ENSPPAG00000034780	GNL3L	100	99.656	Pan_paniscus
ENSG00000130119	GNL3L	100	91.753	ENSPPRG00000001783	GNL3L	100	91.753	Panthera_pardus
ENSG00000130119	GNL3L	100	91.753	ENSPTIG00000007066	GNL3L	100	91.753	Panthera_tigris_altaica
ENSG00000130119	GNL3L	94	72.122	ENSPTRG00000021940	-	99	72.122	Pan_troglodytes
ENSG00000130119	GNL3L	100	99.656	ENSPTRG00000050609	GNL3L	100	99.656	Pan_troglodytes
ENSG00000130119	GNL3L	100	71.502	ENSPANG00000032356	-	100	71.502	Papio_anubis
ENSG00000130119	GNL3L	96	50.702	ENSPKIG00000012014	gnl3l	90	50.702	Paramormyrops_kingsleyae
ENSG00000130119	GNL3L	95	49.110	ENSPMGG00000021338	gnl3l	98	49.110	Periophthalmus_magnuspinnatus
ENSG00000130119	GNL3L	100	88.679	ENSPEMG00000012235	Gnl3l	100	88.679	Peromyscus_maniculatus_bairdii
ENSG00000130119	GNL3L	95	50.874	ENSPCIG00000006327	-	99	51.309	Phascolarctos_cinereus
ENSG00000130119	GNL3L	93	49.910	ENSPFOG00000007874	gnl3l	95	49.910	Poecilia_formosa
ENSG00000130119	GNL3L	93	50.547	ENSPLAG00000021161	gnl3l	95	50.547	Poecilia_latipinna
ENSG00000130119	GNL3L	93	49.910	ENSPMEG00000024050	gnl3l	95	49.910	Poecilia_mexicana
ENSG00000130119	GNL3L	83	49.000	ENSPREG00000021994	gnl3l	88	49.315	Poecilia_reticulata
ENSG00000130119	GNL3L	99	98.261	ENSPPYG00000020383	GNL3L	100	98.643	Pongo_abelii
ENSG00000130119	GNL3L	75	76.538	ENSPCAG00000005304	GNL3L	75	76.538	Procavia_capensis
ENSG00000130119	GNL3L	100	93.643	ENSPCOG00000016430	GNL3L	100	93.643	Propithecus_coquereli
ENSG00000130119	GNL3L	85	90.127	ENSPVAG00000008758	GNL3L	87	90.127	Pteropus_vampyrus
ENSG00000130119	GNL3L	93	49.183	ENSPNYG00000017256	gnl3l	95	49.183	Pundamilia_nyererei
ENSG00000130119	GNL3L	94	48.288	ENSPNAG00000005179	gnl3l	96	47.397	Pygocentrus_nattereri
ENSG00000130119	GNL3L	100	87.842	ENSRNOG00000002509	Gnl3l	100	87.842	Rattus_norvegicus
ENSG00000130119	GNL3L	99	97.074	ENSRBIG00000041351	GNL3L	100	97.074	Rhinopithecus_bieti
ENSG00000130119	GNL3L	99	97.074	ENSRROG00000036933	GNL3L	99	97.074	Rhinopithecus_roxellana
ENSG00000130119	GNL3L	99	95.525	ENSSBOG00000007626	-	100	96.899	Saimiri_boliviensis_boliviensis
ENSG00000130119	GNL3L	94	51.163	ENSSFOG00015008883	gnl3l	95	51.163	Scleropages_formosus
ENSG00000130119	GNL3L	93	49.458	ENSSMAG00000014518	gnl3l	95	49.458	Scophthalmus_maximus
ENSG00000130119	GNL3L	94	48.043	ENSSDUG00000013117	gnl3l	95	48.043	Seriola_dumerili
ENSG00000130119	GNL3L	94	48.221	ENSSLDG00000012278	gnl3l	96	51.158	Seriola_lalandi_dorsalis
ENSG00000130119	GNL3L	78	79.204	ENSSARG00000005360	GNL3L	81	79.204	Sorex_araneus
ENSG00000130119	GNL3L	90	50.280	ENSSPAG00000021373	gnl3l	87	50.280	Stegastes_partitus
ENSG00000130119	GNL3L	100	91.409	ENSSSCG00000012336	GNL3L	100	86.254	Sus_scrofa
ENSG00000130119	GNL3L	88	49.520	ENSTRUG00000013131	gnl3l	91	49.520	Takifugu_rubripes
ENSG00000130119	GNL3L	88	47.166	ENSTNIG00000007323	gnl3l	90	47.166	Tetraodon_nigroviridis
ENSG00000130119	GNL3L	100	87.113	ENSTTRG00000000881	GNL3L	100	87.113	Tursiops_truncatus
ENSG00000130119	GNL3L	83	92.547	ENSUAMG00000009526	GNL3L	93	92.547	Ursus_americanus
ENSG00000130119	GNL3L	100	91.753	ENSUMAG00000019089	GNL3L	100	91.753	Ursus_maritimus
ENSG00000130119	GNL3L	100	90.206	ENSVVUG00000002172	GNL3L	89	90.206	Vulpes_vulpes
ENSG00000130119	GNL3L	99	49.483	ENSXETG00000007700	gnl3l	99	49.483	Xenopus_tropicalis
ENSG00000130119	GNL3L	88	51.852	ENSXCOG00000011839	gnl3l	92	51.527	Xiphophorus_couchianus
ENSG00000130119	GNL3L	93	49.816	ENSXMAG00000007665	gnl3l	95	49.550	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16189514.19487455.21132010.25416956.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005697	telomerase holoenzyme complex	18082603.	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	18082603.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0031397	negative regulation of protein ubiquitination	19487455.	IMP	Process
GO:0031647	regulation of protein stability	19487455.	IDA	Process
GO:0031647	regulation of protein stability	19487455.	IMP	Process
GO:0032091	negative regulation of protein binding	19487455.	IDA	Process
GO:0032211	negative regulation of telomere maintenance via telomerase	18082603.	IMP	Process
GO:0033234	negative regulation of protein sumoylation	22641345.	IMP	Process
GO:0042254	ribosome biogenesis	-	IEA	Process
GO:0090073	positive regulation of protein homodimerization activity	19487455.	IMP	Process
GO:1904816	positive regulation of protein localization to chromosome, telomeric region	19487455.	IDA	Process
GO:1904816	positive regulation of protein localization to chromosome, telomeric region	19487455.	IMP	Process