EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000130589 (Gene tree)
Gene ID: 85441
Gene Symbol: HELZ2
Alias: PDIP1|PRIC285|KIAA1769
Full Name: helicase with zinc finger 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,154 bases
Position: chr20:63,558,086-63,574,239
Accession: 30021
RBP type: canonical RBP
Summary: The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000393257	RNB	PF00773.19	1.8e-49	1	1
ENSP00000417401	RNB	PF00773.19	2.8e-49	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000427522	HELZ2-202	7827	-	ENSP00000393257	2080 (aa)	-	Q9BYK8
ENST00000467148	HELZ2-204	8064	XM_024452006	ENSP00000417401	2649 (aa)	XP_024307774	Q9BYK8
ENST00000370082	HELZ2-201	1827	-	-	- (aa)	-	-
ENST00000479540	HELZ2-206	3079	-	-	- (aa)	-	-
ENST00000478861	HELZ2-205	833	-	-	- (aa)	-	-
ENST00000454223	HELZ2-203	435	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000130589's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000130589	Platelet Function Tests	1.5003400E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000130589	rs73622826	20	63571210	?	Plasma factor VII activating protease levels	30070759	[22.55-56.65] unit increase	39.6	EFO_0009368
ENSG00000130589	rs3810483	20	63562677	?	Red cell distribution width	30595370			EFO_0005192

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000130589's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130589	HELZ2	99	72.751	ENSAMEG00000001622	HELZ2	92	72.556	Ailuropoda_melanoleuca
ENSG00000130589	HELZ2	95	57.106	ENSAPLG00000010386	HELZ2	99	52.070	Anas_platyrhynchos
ENSG00000130589	HELZ2	95	57.474	ENSACAG00000011519	HELZ2	91	53.244	Anolis_carolinensis
ENSG00000130589	HELZ2	100	87.608	ENSANAG00000019546	HELZ2	100	87.721	Aotus_nancymaae
ENSG00000130589	HELZ2	94	47.396	ENSAMXG00000017465	helz2	90	41.170	Astyanax_mexicanus
ENSG00000130589	HELZ2	99	71.780	ENSCAFG00000012968	HELZ2	91	71.196	Canis_familiaris
ENSG00000130589	HELZ2	97	76.873	ENSTSYG00000027453	HELZ2	100	76.873	Carlito_syrichta
ENSG00000130589	HELZ2	99	71.997	ENSCAPG00000010249	HELZ2	91	71.884	Cavia_aperea
ENSG00000130589	HELZ2	99	71.514	ENSCPOG00000006905	HELZ2	91	71.402	Cavia_porcellus
ENSG00000130589	HELZ2	100	87.104	ENSCCAG00000027744	HELZ2	100	87.255	Cebus_capucinus
ENSG00000130589	HELZ2	100	93.663	ENSCATG00000014259	HELZ2	100	92.166	Cercocebus_atys
ENSG00000130589	HELZ2	99	72.642	ENSCLAG00000006292	HELZ2	91	72.428	Chinchilla_lanigera
ENSG00000130589	HELZ2	100	94.035	ENSCSAG00000016417	HELZ2	94	94.035	Chlorocebus_sabaeus
ENSG00000130589	HELZ2	96	62.016	ENSCPBG00000014633	HELZ2	91	55.072	Chrysemys_picta_bellii
ENSG00000130589	HELZ2	100	94.073	ENSCANG00000033242	HELZ2	100	94.073	Colobus_angolensis_palliatus
ENSG00000130589	HELZ2	100	70.672	ENSCGRG00001016744	Helz2	91	71.348	Cricetulus_griseus_chok1gshd
ENSG00000130589	HELZ2	100	71.338	ENSCGRG00000012155	Helz2	92	71.189	Cricetulus_griseus_crigri
ENSG00000130589	HELZ2	88	35.264	ENSDARG00000012446	zgc:113057	97	35.264	Danio_rerio
ENSG00000130589	HELZ2	96	47.423	ENSDARG00000016527	helz2	94	41.658	Danio_rerio
ENSG00000130589	HELZ2	92	46.803	ENSDARG00000012600	si:dkey-97a13.6	96	46.803	Danio_rerio
ENSG00000130589	HELZ2	99	66.970	ENSDNOG00000017809	HELZ2	98	66.640	Dasypus_novemcinctus
ENSG00000130589	HELZ2	100	70.832	ENSDORG00000005596	Helz2	92	70.907	Dipodomys_ordii
ENSG00000130589	HELZ2	73	75.124	ENSETEG00000009947	-	62	76.289	Echinops_telfairi
ENSG00000130589	HELZ2	99	73.873	ENSEASG00005023168	HELZ2	91	73.688	Equus_asinus_asinus
ENSG00000130589	HELZ2	99	74.103	ENSECAG00000013636	HELZ2	91	76.761	Equus_caballus
ENSG00000130589	HELZ2	78	77.778	ENSEEUG00000004620	HELZ2	82	77.778	Erinaceus_europaeus
ENSG00000130589	HELZ2	92	47.967	ENSELUG00000013322	helz2	90	41.885	Esox_lucius
ENSG00000130589	HELZ2	95	57.623	ENSFALG00000005852	HELZ2	91	53.161	Ficedula_albicollis
ENSG00000130589	HELZ2	99	69.343	ENSFDAG00000013078	HELZ2	92	69.291	Fukomys_damarensis
ENSG00000130589	HELZ2	96	56.311	ENSGALG00000006138	HELZ2	91	52.573	Gallus_gallus
ENSG00000130589	HELZ2	95	61.240	ENSGAGG00000019429	HELZ2	91	54.865	Gopherus_agassizii
ENSG00000130589	HELZ2	100	98.304	ENSGGOG00000008640	HELZ2	100	98.304	Gorilla_gorilla
ENSG00000130589	HELZ2	99	71.711	ENSHGLG00000013895	HELZ2	92	71.487	Heterocephalus_glaber_female
ENSG00000130589	HELZ2	99	69.812	ENSHGLG00100002953	HELZ2	92	69.217	Heterocephalus_glaber_male
ENSG00000130589	HELZ2	73	34.375	ENSIPUG00000017627	zgc:113057	99	34.375	Ictalurus_punctatus
ENSG00000130589	HELZ2	100	72.320	ENSSTOG00000023572	HELZ2	92	72.307	Ictidomys_tridecemlineatus
ENSG00000130589	HELZ2	100	70.124	ENSJJAG00000021775	Helz2	91	70.734	Jaculus_jaculus
ENSG00000130589	HELZ2	95	54.220	ENSLACG00000008155	HELZ2	91	47.023	Latimeria_chalumnae
ENSG00000130589	HELZ2	95	54.337	ENSLOCG00000001839	si:dkey-97a13.6	91	48.258	Lepisosteus_oculatus
ENSG00000130589	HELZ2	95	51.256	ENSLOCG00000001770	helz2	91	47.459	Lepisosteus_oculatus
ENSG00000130589	HELZ2	100	93.847	ENSMFAG00000002329	HELZ2	100	93.847	Macaca_fascicularis
ENSG00000130589	HELZ2	100	93.658	ENSMMUG00000006070	HELZ2	100	93.361	Macaca_mulatta
ENSG00000130589	HELZ2	100	93.960	ENSMNEG00000044829	HELZ2	94	93.960	Macaca_nemestrina
ENSG00000130589	HELZ2	97	94.385	ENSMLEG00000034372	HELZ2	98	94.385	Mandrillus_leucophaeus
ENSG00000130589	HELZ2	95	57.215	ENSMGAG00000006941	HELZ2	91	53.080	Meleagris_gallopavo
ENSG00000130589	HELZ2	100	71.402	ENSMAUG00000000857	Helz2	92	71.252	Mesocricetus_auratus
ENSG00000130589	HELZ2	100	70.071	ENSMICG00000027046	HELZ2	100	70.145	Microcebus_murinus
ENSG00000130589	HELZ2	100	69.941	ENSMOCG00000016283	Helz2	92	69.831	Microtus_ochrogaster
ENSG00000130589	HELZ2	95	65.891	ENSMODG00000016966	-	91	59.529	Monodelphis_domestica
ENSG00000130589	HELZ2	100	69.010	MGP_CAROLIEiJ_G0024801	Helz2	92	68.601	Mus_caroli
ENSG00000130589	HELZ2	100	68.666	ENSMUSG00000027580	Helz2	92	68.492	Mus_musculus
ENSG00000130589	HELZ2	100	68.718	MGP_PahariEiJ_G0026249	Helz2	92	68.614	Mus_pahari
ENSG00000130589	HELZ2	100	68.437	MGP_SPRETEiJ_G0025727	Helz2	92	68.226	Mus_spretus
ENSG00000130589	HELZ2	99	70.940	ENSMPUG00000008361	HELZ2	92	70.914	Mustela_putorius_furo
ENSG00000130589	HELZ2	99	72.956	ENSMLUG00000014588	HELZ2	92	73.097	Myotis_lucifugus
ENSG00000130589	HELZ2	100	71.144	ENSNGAG00000013840	Helz2	92	70.792	Nannospalax_galili
ENSG00000130589	HELZ2	100	93.318	ENSNLEG00000010083	-	100	93.318	Nomascus_leucogenys
ENSG00000130589	HELZ2	97	68.293	ENSMEUG00000006147	HELZ2	97	68.293	Notamacropus_eugenii
ENSG00000130589	HELZ2	99	70.004	ENSODEG00000007200	HELZ2	92	69.821	Octodon_degus
ENSG00000130589	HELZ2	94	67.273	ENSOANG00000004941	-	99	66.667	Ornithorhynchus_anatinus
ENSG00000130589	HELZ2	100	72.191	ENSOGAG00000031068	HELZ2	91	72.228	Otolemur_garnettii
ENSG00000130589	HELZ2	100	99.018	ENSPPAG00000037593	HELZ2	100	99.018	Pan_paniscus
ENSG00000130589	HELZ2	99	73.652	ENSPPRG00000012585	HELZ2	99	73.180	Panthera_pardus
ENSG00000130589	HELZ2	99	98.476	ENSPTRG00000013743	HELZ2	98	98.476	Pan_troglodytes
ENSG00000130589	HELZ2	100	94.073	ENSPANG00000020634	HELZ2	100	92.612	Papio_anubis
ENSG00000130589	HELZ2	94	50.129	ENSPKIG00000005935	helz2	95	44.225	Paramormyrops_kingsleyae
ENSG00000130589	HELZ2	95	60.569	ENSPSIG00000012565	HELZ2	89	60.569	Pelodiscus_sinensis
ENSG00000130589	HELZ2	100	71.159	ENSPEMG00000016538	Helz2	92	70.690	Peromyscus_maniculatus_bairdii
ENSG00000130589	HELZ2	99	54.328	ENSPCIG00000017966	HELZ2	99	60.044	Phascolarctos_cinereus
ENSG00000130589	HELZ2	100	93.394	ENSPPYG00000011241	HELZ2	100	93.394	Pongo_abelii
ENSG00000130589	HELZ2	99	66.487	ENSPCAG00000001068	HELZ2	100	66.933	Procavia_capensis
ENSG00000130589	HELZ2	100	74.615	ENSPCOG00000017149	HELZ2	100	74.690	Propithecus_coquereli
ENSG00000130589	HELZ2	92	82.051	ENSPVAG00000007183	HELZ2	97	82.051	Pteropus_vampyrus
ENSG00000130589	HELZ2	94	43.864	ENSPNAG00000016859	helz2	95	39.224	Pygocentrus_nattereri
ENSG00000130589	HELZ2	99	67.642	ENSRNOG00000013267	Helz2	88	67.741	Rattus_norvegicus
ENSG00000130589	HELZ2	100	94.337	ENSRBIG00000044653	HELZ2	100	94.337	Rhinopithecus_bieti
ENSG00000130589	HELZ2	100	94.262	ENSRROG00000009088	HELZ2	100	92.790	Rhinopithecus_roxellana
ENSG00000130589	HELZ2	100	87.330	ENSSBOG00000033345	HELZ2	100	87.406	Saimiri_boliviensis_boliviensis
ENSG00000130589	HELZ2	95	64.083	ENSSHAG00000018163	HELZ2	92	60.186	Sarcophilus_harrisii
ENSG00000130589	HELZ2	96	46.560	ENSSFOG00015020580	helz2	92	43.448	Scleropages_formosus
ENSG00000130589	HELZ2	63	75.479	ENSSARG00000010235	-	69	75.479	Sorex_araneus
ENSG00000130589	HELZ2	51	45.981	ENSSPUG00000018590	-	98	45.981	Sphenodon_punctatus
ENSG00000130589	HELZ2	97	68.378	ENSSSCG00000003306	HELZ2	90	68.378	Sus_scrofa
ENSG00000130589	HELZ2	95	58.140	ENSTGUG00000006981	HELZ2	99	53.826	Taeniopygia_guttata
ENSG00000130589	HELZ2	99	70.901	ENSUAMG00000025224	-	94	70.160	Ursus_americanus
ENSG00000130589	HELZ2	99	71.713	ENSVVUG00000015158	HELZ2	89	71.412	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0004004	ATP-dependent RNA helicase activity	21873635.	IBA	Function
GO:0004540	ribonuclease activity	-	IEA	Function
GO:0005515	protein binding	16239304.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0019216	regulation of lipid metabolic process	-	TAS	Process
GO:0030374	nuclear receptor transcription coactivator activity	16239304.	IDA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	16239304.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0090501	RNA phosphodiester bond hydrolysis	-	IEA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr20	63564957	Missense_Mutation	NA	E1289Q	0.16
BLCA	chr20	63561184	Silent	novel	S2348S	0.2
BLCA	chr20	63563053	Silent	novel	F1923F	0.4
BLCA	chr20	63567171	Silent	rs780288859	H729H	0.18
BLCA	chr20	63567198	Silent	NA	L720L	0.2
BLCA	chr20	63567363	Silent	NA	L665L	0.27
BLCA	chr20	63568721	Missense_Mutation	novel	A456G	0.5
BLCA	chr20	63569381	Silent	rs147054984	L285L	0.29
BLCA	chr20	63560575	Missense_Mutation	novel	I2468M	0.23
BLCA	chr20	63569471	Silent	rs143216041	F255F	0.45
BLCA	chr20	63562295	Silent	novel	L2130L	0.89
BLCA	chr20	63564957	Missense_Mutation	NA	E1289Q	0.52
BLCA	chr20	63564094	Silent	NA	L1576L	0.39
BLCA	chr20	63561134	Missense_Mutation	novel	A2365G	0.17
BLCA	chr20	63565287	Missense_Mutation	novel	G1179R	0.2
BLCA	chr20	63561729	Silent	novel	R2236R	0.23
BLCA	chr20	63567605	Missense_Mutation	novel	E585K	0.44
BLCA	chr20	63560242	Missense_Mutation	novel	S2529C	0.33
BLCA	chr20	63562735	Silent	rs776883983	L2029L	0.45
BLCA	chr20	63564931	Silent	novel	L1297L	0.27
BLCA	chr20	63563847	Missense_Mutation	rs763147564	G1659S	0.35	RNB
BLCA	chr20	63568795	Silent	rs576078631	F431F	0.27
BRCA	chr20	63567455	Missense_Mutation	rs369045635	R635W	0.2
BRCA	chr20	63565704	Missense_Mutation	novel	A1040S	0.16
BRCA	chr20	63565706	Missense_Mutation	novel	C1039F	0.15
BRCA	chr20	63564067	Silent	rs781050293	H1585H	0.28
BRCA	chr20	63563941	Missense_Mutation	NA	M1627I	0.21	RNB
BRCA	chr20	63570506	Missense_Mutation	novel	E190Q	0.12
BRCA	chr20	63561651	Missense_Mutation	NA	R2262S	0.32
BRCA	chr20	63566068	Silent	rs749753822	L918L	0.31
BRCA	chr20	63560920	Missense_Mutation	rs151068704	L2386F	0.11
BRCA	chr20	63560476	Splice_Region	novel		0.16
BRCA	chr20	63565885	Silent	NA	E979E	0.3
CESC	chr20	63567202	Missense_Mutation	novel	R719H	0.2
CESC	chr20	63567115	Missense_Mutation	NA	A748V	0.22
CESC	chr20	63572220	Missense_Mutation	NA	E56K	0.48
CESC	chr20	63564366	Missense_Mutation	rs61739518	V1486I	0.44	RNB
CESC	chr20	63565561	Silent	novel	V1087V	0.4
CESC	chr20	63560691	Missense_Mutation	NA	G2430S	0.3
CESC	chr20	63563680	Silent	rs764479060	H1714H	0.26
CESC	chr20	63570508	Missense_Mutation	rs563895075	S189C	0.39
CESC	chr20	63564711	Missense_Mutation	NA	H1371Y	0.31	RNB
CESC	chr20	63559948	Missense_Mutation	NA	Q2602R	0.3
CESC	chr20	63561241	Silent	rs561435122	F2329F	0.34
CESC	chr20	63565094	Missense_Mutation	rs759835133	R1243Q	0.44
CESC	chr20	63567441	Silent	rs750932832	A639A	0.7
CESC	chr20	63568507	Silent	rs201934461	A527A	0.29
CESC	chr20	63564193	Silent	rs547243901	S1543S	0.42
CESC	chr20	63564004	Silent	novel	V1606V	0.86
CESC	chr20	63563770	Silent	novel	Q1684Q	0.31
CESC	chr20	63564266	Missense_Mutation	rs771795577	R1519H	0.21	RNB
CESC	chr20	63567162	Silent	rs756138675	A732A	0.27
CESC	chr20	63569204	Missense_Mutation	novel	Q344H	0.5
CESC	chr20	63567663	Intron	novel		0.35
CESC	chr20	63567373	Missense_Mutation	NA	S662F	0.14
CESC	chr20	63564825	Missense_Mutation	rs538816738	R1333C	0.44
CESC	chr20	63565772	Missense_Mutation	rs145321285	A1017V	0.18
CESC	chr20	63568509	Missense_Mutation	rs143335677	A527T	0.57
CESC	chr20	63563692	Silent	NA	F1710F	0.25
COAD	chr20	63563885	Missense_Mutation	rs192795569	A1646V	0.67	RNB
COAD	chr20	63567352	Missense_Mutation	novel	A669V	0.17
COAD	chr20	63570188	Intron	rs775712451		0.31
COAD	chr20	63561898	Frame_Shift_Del	rs745497383	*R2206Vfs29**	0.33
COAD	chr20	63565221	Missense_Mutation	rs145219009	E1201K	0.16
COAD	chr20	63560252	Missense_Mutation	rs573248815	A2526T	0.23
COAD	chr20	63560837	Silent	novel	R2413R	0.27
COAD	chr20	63564250	Missense_Mutation	NA	M1524I	0.15	RNB
COAD	chr20	63562380	Missense_Mutation	rs370768380	R2102H	0.28
COAD	chr20	63559189	3'Flank	novel		0.5
COAD	chr20	63561898	Frame_Shift_Del	rs745497383	*R2206Vfs29**	0.24
COAD	chr20	63564887	Missense_Mutation	novel	D1312G	0.13
COAD	chr20	63572257	Silent	rs373635043	P43P	0.38
COAD	chr20	63565076	Missense_Mutation	rs768418245	R1249H	0.31
COAD	chr20	63562866	Missense_Mutation	rs375422831	A1986T	0.29
COAD	chr20	63565192	Silent	rs760626528	T1210T	0.25
COAD	chr20	63565993	Silent	rs748241928	P943P	0.37
COAD	chr20	63564265	Silent	rs539893308	R1519R	0.45
COAD	chr20	63567636	Intron	rs760771051		0.48
COAD	chr20	63562952	Missense_Mutation	rs772680501	A1957V	0.35
COAD	chr20	63564105	Missense_Mutation	rs147812640	R1573W	0.36	RNB
COAD	chr20	63564889	Silent	novel	S1311S	0.4
COAD	chr20	63565766	Missense_Mutation	rs769150906	T1019M	0.22
COAD	chr20	63560251	Missense_Mutation	rs758785414	A2526V	0.33
COAD	chr20	63563976	Missense_Mutation	rs776067170	E1616K	0.26	RNB
COAD	chr20	63564193	Silent	rs547243901	S1543S	0.23
COAD	chr20	63570819	Frame_Shift_Del	novel	*Q110Rfs61**	0.41
COAD	chr20	63565666	Silent	rs45548036	T1052T	0.15
COAD	chr20	63565420	Silent	rs754907014	F1134F	0.33
COAD	chr20	63567083	Missense_Mutation	rs769167544	V759M	0.32
COAD	chr20	63562380	Missense_Mutation	rs370768380	R2102H	0.13
COAD	chr20	63560620	Silent	rs41298358	P2453P	0.16
COAD	chr20	63563733	Missense_Mutation	NA	A1697T	0.31
COAD	chr20	63564770	Missense_Mutation	novel	C1351Y	0.07	RNB
COAD	chr20	63561876	Frame_Shift_Del	NA	*G2213Vfs22**	0.14
COAD	chr20	63563473	Silent	rs771456510	H1783H	0.33
COAD	chr20	63570348	Intron	novel		0.25
COAD	chr20	63564774	Missense_Mutation	NA	A1350S	0.12	RNB
COAD	chr20	63564893	Frame_Shift_Del	novel	*P1310Rfs32**	0.09
COAD	chr20	63570249	Intron	rs764718022		0.18
COAD	chr20	63562539	Missense_Mutation	rs767837261	P2095S	0.38
COAD	chr20	63562551	Missense_Mutation	NA	V2091I	0.24
COAD	chr20	63559189	3'Flank	novel		0.25
COAD	chr20	63564892	Silent	rs781767607	P1310P	0.21
COAD	chr20	63564192	Missense_Mutation	rs759047851	E1544K	0.35	RNB
COAD	chr20	63565614	Missense_Mutation	novel	A1070T	0.49
COAD	chr20	63562071	Splice_Site	novel	X2177_splice	0.38
COAD	chr20	63559195	3'Flank	novel		0.25
COAD	chr20	63568842	Missense_Mutation	novel	S416G	0.48
COAD	chr20	63570485	Intron	rs768843788		0.15
COAD	chr20	63562615	Silent	rs764192471	F2069F	0.43
COAD	chr20	63563886	Missense_Mutation	NA	A1646T	0.32	RNB
COAD	chr20	63563021	Missense_Mutation	rs200467624	R1934Q	0.11
COAD	chr20	63570587	Missense_Mutation	rs771275462	R163C	0.14
COAD	chr20	63569502	Missense_Mutation	rs745748003	S245L	0.17
COAD	chr20	63561840	Missense_Mutation	novel	S2225L	0.17
COAD	chr20	63567202	Missense_Mutation	novel	R719H	0.16
COAD	chr20	63567603	Missense_Mutation	novel	E585D	0.17
COAD	chr20	63569242	Missense_Mutation	rs201938713	V332M	0.12
COAD	chr20	63563796	Missense_Mutation	rs141999472	R1676C	0.14	RNB
COAD	chr20	63568493	Missense_Mutation	novel	G532V	0.21
DLBC	chr20	63562998	Missense_Mutation	novel	A1942P	0.28
DLBC	chr20	63564415	Silent	novel	P1469P	0.73
ESCA	chr20	63564262	Silent	rs749599121	A1520A	0.37
ESCA	chr20	63562860	Missense_Mutation	rs200554251	R1988C	0.16
ESCA	chr20	63562786	Silent	rs140899217	L2012L	0.06
ESCA	chr20	63562723	Silent	novel	L2033L	0.33
ESCA	chr20	63572193	Missense_Mutation	rs374328737	A65T	0.34
ESCA	chr20	63561220	Silent	novel	V2336V	0.13
ESCA	chr20	63563601	Silent	novel	L1741L	0.5
GBM	chr20	63567052	Missense_Mutation	NA	G769D	0.05
GBM	chr20	63567280	Missense_Mutation	NA	A693V	0.57
GBM	chr20	63561968	Silent	rs778696138	I2182I	0.43
GBM	chr20	63565277	Missense_Mutation	rs766699437	A1182V	0.18
GBM	chr20	63565447	Silent	rs751414456	E1125E	0.44
GBM	chr20	63565969	Silent	rs115761351	V951V	0.24
GBM	chr20	63568795	Silent	rs576078631	F431F	0.26
GBM	chr20	63568931	Missense_Mutation	rs748068037	A386V	0.34
GBM	chr20	63567252	Silent	novel	R702R	0.12
HNSC	chr20	63560602	Silent	rs141657913	H2459H	0.28
HNSC	chr20	63566024	Missense_Mutation	novel	R933H	0.24
HNSC	chr20	63562587	Missense_Mutation	novel	P2079S	0.31
HNSC	chr20	63569434	Missense_Mutation	rs772810619	G268R	0.21
HNSC	chr20	63566866	Missense_Mutation	novel	C831S	0.13
HNSC	chr20	63564893	Missense_Mutation	rs748486054	P1310L	0.09
HNSC	chr20	63562347	Missense_Mutation	rs571327252	A2113V	0.31
HNSC	chr20	63572243	Missense_Mutation	novel	T48S	0.53
HNSC	chr20	63572234	Missense_Mutation	NA	S51C	0.17
HNSC	chr20	63565765	Silent	rs778538016	T1019T	0.17
HNSC	chr20	63561633	Silent	novel	S2268S	0.39
HNSC	chr20	63562683	Missense_Mutation	novel	Q2047K	0.14
HNSC	chr20	63565420	Silent	rs754907014	F1134F	0.22
KIRC	chr20	63569615	Missense_Mutation	novel	F207L	0.44
KIRC	chr20	63564758	Frame_Shift_Del	novel	*D1355Vfs86**	0.31	RNB
KIRC	chr20	63561735	Silent	NA	L2234L	0.26
KIRP	chr20	63565404	Missense_Mutation	novel	E1140K	0.39
KIRP	chr20	63569391	Frame_Shift_Del	novel	*N282Ifs33**	0.56
KIRP	chr20	63566857	Missense_Mutation	novel	S834C	0.33
KIRP	chr20	63567160	Missense_Mutation	NA	R733Q	0.06
KIRP	chr20	63562198	Missense_Mutation	novel	P2135A	0.26
KIRP	chr20	63561734	Missense_Mutation	NA	R2235G	0.35
KIRP	chr20	63560507	Missense_Mutation	novel	K2491M	0.22
KIRP	chr20	63570798	Missense_Mutation	rs780287876	R117W	0.19
KIRP	chr20	63563878	Silent	novel	G1648G	0.29
KIRP	chr20	63572129	Missense_Mutation	NA	S86F	0.21
KIRP	chr20	63559358	Missense_Mutation	novel	L2613P	0.44
KIRP	chr20	63568632	Missense_Mutation	rs547559351	D486N	0.31
LGG	chr20	63565364	Missense_Mutation	novel	G1153D	0.67
LGG	chr20	63564166	Silent	NA	L1552L	0.28
LGG	chr20	63565419	Missense_Mutation	NA	V1135M	0.17
LGG	chr20	63560860	Missense_Mutation	novel	L2406M	0.07
LGG	chr20	63562153	Missense_Mutation	rs757488890	R2150C	0.44
LGG	chr20	63567171	Silent	rs780288859	H729H	0.12
LGG	chr20	63569563	Missense_Mutation	novel	R225C	0.54
LGG	chr20	63561690	Silent	NA	A2249A	0.08
LGG	chr20	63569343	Missense_Mutation	rs779018772	N298S	0.43
LGG	chr20	63572161	Frame_Shift_Del	novel	*W76Gfs95**	0.44
LGG	chr20	63564292	Silent	rs45625632	P1510P	0.5
LGG	chr20	63563581	Silent	novel	V1747V	0.42
LIHC	chr20	63567120	Silent	rs777659473	T746T	0.08
LIHC	chr20	63568930	Silent	rs151002657	A386A	0.29
LIHC	chr20	63565369	Silent	NA	S1151S	0.36
LIHC	chr20	63572174	Missense_Mutation	NA	D71V	0.28
LIHC	chr20	63563530	Silent	rs760787217	T1764T	0.26
LIHC	chr20	63559327	Silent	rs141769251	L2623L	0.3
LIHC	chr20	63565163	Missense_Mutation	novel	N1220S	0.06
LUAD	chr20	63567282	Silent	NA	L692L	0.4
LUAD	chr20	63568612	Missense_Mutation	NA	Q492H	0.1
LUAD	chr20	63562158	Missense_Mutation	NA	G2148V	0.37
LUAD	chr20	63566133	Missense_Mutation	NA	V897M	0.38
LUAD	chr20	63567224	Missense_Mutation	novel	A712T	0.25
LUAD	chr20	63566991	Silent	novel	P789P	0.19
LUAD	chr20	63563181	Frame_Shift_Del	novel	*D1881Tfs89**	0.38
LUAD	chr20	63560565	Missense_Mutation	rs748230640	V2472L	0.18
LUAD	chr20	63561439	Silent	novel	R2288R	0.16
LUAD	chr20	63566882	Missense_Mutation	novel	E826K	0.28
LUAD	chr20	63569452	Missense_Mutation	novel	V262L	0.28
LUAD	chr20	63567213	Silent	novel	T715T	0.15
LUAD	chr20	63565502	Missense_Mutation	novel	A1107V	0.14
LUAD	chr20	63561927	Missense_Mutation	NA	Q2196R	0.64
LUAD	chr20	63567192	Silent	novel	L722L	0.16
LUAD	chr20	63566857	Missense_Mutation	novel	S834F	0.48
LUAD	chr20	63567318	Silent	novel	P680P	0.37
LUAD	chr20	63561628	Missense_Mutation	rs143065747	R2270Q	0.31
LUAD	chr20	63565882	Silent	novel	P980P	0.14
LUSC	chr20	63569340	Missense_Mutation	NA	R299L	0.35
LUSC	chr20	63564037	Silent	rs556268627	R1595R	0.24
LUSC	chr20	63564281	Missense_Mutation	novel	G1514A	0.16	RNB
LUSC	chr20	63569201	Missense_Mutation	novel	R345S	0.12
LUSC	chr20	63561452	Missense_Mutation	NA	H2284L	0.36
LUSC	chr20	63568831	Silent	novel	L419L	0.91
LUSC	chr20	63564264	Missense_Mutation	rs115211910	A1520T	0.17	RNB
LUSC	chr20	63567031	Missense_Mutation	novel	R776Q	0.1
LUSC	chr20	63566932	Missense_Mutation	NA	E809V	0.43
LUSC	chr20	63563661	Nonsense_Mutation	NA	Q1721*	0.38
LUSC	chr20	63567170	Missense_Mutation	rs201624376	E730K	0.32
LUSC	chr20	63566167	Silent	novel	G885G	0.33
LUSC	chr20	63565815	Missense_Mutation	novel	E1003Q	0.16
LUSC	chr20	63562120	Missense_Mutation	novel	V2161I	0.11
LUSC	chr20	63560854	Missense_Mutation	rs747775785	R2408W	0.12
LUSC	chr20	63564836	Missense_Mutation	novel	R1329L	0.23
LUSC	chr20	63559954	Missense_Mutation	novel	R2600L	0.25
LUSC	chr20	63568407	Missense_Mutation	novel	V561F	0.21
LUSC	chr20	63567141	Silent	NA	F739F	0.24
LUSC	chr20	63567273	Silent	rs540033381	D695D	0.35
LUSC	chr20	63565432	Silent	NA	R1130R	0.45
LUSC	chr20	63565553	Missense_Mutation	NA	G1090E	0.22
LUSC	chr20	63561260	Missense_Mutation	novel	L2323S	0.16
LUSC	chr20	63570515	Missense_Mutation	novel	V187F	0.25
LUSC	chr20	63564894	Missense_Mutation	NA	P1310S	0.21
LUSC	chr20	63565440	Missense_Mutation	rs151132433	R1128W	0.2
LUSC	chr20	63565897	Silent	novel	E975E	0.41
LUSC	chr20	63561198	Missense_Mutation	novel	A2344P	0.31
MESO	chr20	63569378	Silent	novel	G286G	0.2
MESO	chr20	63568993	Silent	NA	T365T	0.22
OV	chr20	63559282	Missense_Mutation	NA	Q2638H	0.23
PAAD	chr20	63564606	Missense_Mutation	novel	M1406L	0.31	RNB
PRAD	chr20	63564985	Silent	rs777998717	P1279P	0.09
PRAD	chr20	63568989	Missense_Mutation	rs754687332	R367W	0.08
PRAD	chr20	63564219	Missense_Mutation	novel	L1535I	0.3	RNB
READ	chr20	63569571	Missense_Mutation	NA	R222Q	0.16
SARC	chr20	63563753	Missense_Mutation	rs774013881	A1690V	0.32	RNB
SARC	chr20	63567322	Missense_Mutation	novel	T679N	0.39
SARC	chr20	63561900	Missense_Mutation	rs200091305	P2205L	0.28
SARC	chr20	63563713	Silent	rs765414328	I1703I	0.27
SKCM	chr20	63567034	Missense_Mutation	novel	P775L	0.32
SKCM	chr20	63570761	Missense_Mutation	novel	A129V	0.25
SKCM	chr20	63568534	Silent	novel	K518K	0.55
SKCM	chr20	63561629	Missense_Mutation	rs201218245	R2270W	0.34
SKCM	chr20	63561630	Silent	novel	P2269P	0.37
SKCM	chr20	63564972	Missense_Mutation	rs755141131	R1284W	0.65
SKCM	chr20	63562861	Silent	NA	F1987F	0.15
SKCM	chr20	63560856	Frame_Shift_Del	novel	*D2407Afs38**	0.4
SKCM	chr20	63561873	Missense_Mutation	novel	P2214L	0.38
SKCM	chr20	63564231	Nonsense_Mutation	NA	Q1531*	0.15	RNB
SKCM	chr20	63565634	Missense_Mutation	rs144293106	P1063L	0.68
SKCM	chr20	63565635	Missense_Mutation	novel	P1063S	0.68
SKCM	chr20	63568675	Silent	novel	F471F	0.69
SKCM	chr20	63568494	Missense_Mutation	novel	G532R	0.11
SKCM	chr20	63562082	Silent	novel	Q2173Q	0.39
SKCM	chr20	63560923	Missense_Mutation	NA	L2385F	0.14
SKCM	chr20	63561193	Silent	novel	A2345A	0.13
SKCM	chr20	63564049	Silent	NA	P1591P	0.24
SKCM	chr20	63572140	Silent	NA	P82P	0.33
SKCM	chr20	63565868	Missense_Mutation	rs769170138	A985V	0.76
SKCM	chr20	63563047	Silent	NA	G1925G	0.33
SKCM	chr20	63570750	Missense_Mutation	rs776295297	G133R	0.73
SKCM	chr20	63569242	Missense_Mutation	rs201938713	V332M	0.16
SKCM	chr20	63561457	Silent	NA	T2282T	0.27
SKCM	chr20	63572107	Splice_Site	NA	X93_splice	0.46
SKCM	chr20	63560918	Silent	rs377498739	L2386L	0.1
SKCM	chr20	63563212	Silent	NA	F1870F	0.13
SKCM	chr20	63563908	Silent	NA	L1638L	0.48
SKCM	chr20	63567137	Missense_Mutation	rs114630740	E741K	0.19
SKCM	chr20	63561172	Silent	NA	L2352L	0.17
SKCM	chr20	63570690	Missense_Mutation	NA	L153F	0.19
SKCM	chr20	63565218	Silent	NA	L1202L	0.56
SKCM	chr20	63568415	Missense_Mutation	NA	S558F	0.59
SKCM	chr20	63568887	Silent	NA	L401L	0.42
SKCM	chr20	63568454	Missense_Mutation	NA	P545L	0.21
SKCM	chr20	63567257	Missense_Mutation	novel	P701S	0.5
SKCM	chr20	63572319	Missense_Mutation	NA	P23S	0.59
SKCM	chr20	63563810	Missense_Mutation	NA	A1671D	0.44	RNB
SKCM	chr20	63570568	Missense_Mutation	NA	P169L	0.12
SKCM	chr20	63563797	Silent	NA	I1675I	0.31
SKCM	chr20	63561441	Missense_Mutation	rs202204982	R2288W	0.51
SKCM	chr20	63563508	Missense_Mutation	NA	P1772S	0.38
SKCM	chr20	63568975	Silent	NA	F371F	0.22
SKCM	chr20	63567060	Silent	rs147456257	H766H	0.13
SKCM	chr20	63569625	Missense_Mutation	novel	G204E	0.5
SKCM	chr20	63560610	Silent	NA	L2457L	0.16
SKCM	chr20	63565645	Silent	NA	A1059A	0.09
SKCM	chr20	63568993	Silent	NA	T365T	0.11
SKCM	chr20	63564745	Silent	novel	V1359V	0.5
SKCM	chr20	63559327	Silent	rs141769251	L2623L	0.37
SKCM	chr20	63565794	Missense_Mutation	rs570101866	R1010C	0.27
SKCM	chr20	63563886	Missense_Mutation	NA	A1646T	0.4	RNB
SKCM	chr20	63562319	Silent	NA	L2122L	0.28
SKCM	chr20	63565795	Silent	NA	S1009S	0.19
SKCM	chr20	63563136	Silent	NA	L1896L	0.44
SKCM	chr20	63565856	Missense_Mutation	rs747901408	A989V	0.23
SKCM	chr20	63567639	Intron	novel		0.35
SKCM	chr20	63560060	Missense_Mutation	rs147749912	R2565C	0.16
SKCM	chr20	63562343	Silent	NA	S2114S	0.33
SKCM	chr20	63566171	Missense_Mutation	novel	P884L	0.15
SKCM	chr20	63566172	Missense_Mutation	novel	P884S	0.15
SKCM	chr20	63561217	Silent	novel	I2337I	0.27
SKCM	chr20	63564773	Missense_Mutation	novel	A1350V	0.22	RNB
SKCM	chr20	63566857	Missense_Mutation	novel	S834F	0.33
SKCM	chr20	63564894	Missense_Mutation	NA	P1310S	0.38
SKCM	chr20	63562162	Missense_Mutation	novel	P2147S	0.38
SKCM	chr20	63562163	Silent	novel	I2146I	0.38
STAD	chr20	63564809	Missense_Mutation	NA	R1338H	0.19	RNB
STAD	chr20	63572490	5'Flank	novel		0.75
STAD	chr20	63561169	Silent	rs146799004	D2353D	0.1
STAD	chr20	63564877	Silent	NA	T1315T	0.09
STAD	chr20	63567023	Missense_Mutation	NA	P779T	0.28
STAD	chr20	63566133	Missense_Mutation	NA	V897M	0.29
STAD	chr20	63565004	Missense_Mutation	NA	R1273Q	0.44
STAD	chr20	63565608	Missense_Mutation	rs539347211	D1072N	0.15
STAD	chr20	63562760	Missense_Mutation	novel	S2021N	0.38
STAD	chr20	63569242	Missense_Mutation	rs201938713	V332M	0.38
STAD	chr20	63572153	Missense_Mutation	novel	H78R	0.24
STAD	chr20	63561664	Missense_Mutation	rs767730930	R2258H	0.09
STAD	chr20	63565703	Missense_Mutation	rs374824256	A1040V	0.16
STAD	chr20	63565546	Silent	rs368505725	D1092D	0.25
STAD	chr20	63559971	Silent	NA	V2594V	0.13
STAD	chr20	63564264	Missense_Mutation	rs115211910	A1520T	0.42	RNB
STAD	chr20	63566853	Silent	rs376282035	H835H	0.37
STAD	chr20	63569369	Missense_Mutation	novel	E289D	0.48
STAD	chr20	63561349	Splice_Site	NA	X2318_splice	0.1
STAD	chr20	63565385	Frame_Shift_Del	novel	*P1146Rfs50**	0.14
STAD	chr20	63569471	Silent	rs143216041	F255F	0.43
STAD	chr20	63564725	Missense_Mutation	NA	C1366Y	0.29	RNB
STAD	chr20	63563142	Missense_Mutation	NA	G1894S	0.33
STAD	chr20	63564921	Missense_Mutation	rs576077055	G1301S	0.1
STAD	chr20	63561173	Missense_Mutation	NA	L2352P	0.23
STAD	chr20	63564193	Silent	rs547243901	S1543S	0.4
STAD	chr20	63569518	Missense_Mutation	rs61745755	R240C	0.36
STAD	chr20	63561196	Silent	novel	A2344A	0.26
STAD	chr20	63569517	Missense_Mutation	rs377344395	R240H	0.38
STAD	chr20	63565667	Missense_Mutation	rs367562440	T1052M	0.08
STAD	chr20	63566971	Missense_Mutation	rs79249043	A796V	0.13
THCA	chr20	63568462	Missense_Mutation	novel	I542M	0.54
THCA	chr20	63567120	Silent	rs777659473	T746T	0.33
THCA	chr20	63567146	Frame_Shift_Del	novel	*V738Sfs62**	0.35
THYM	chr20	63560263	Missense_Mutation	rs561821964	T2522M	0.12
UCEC	chr20	63563990	Missense_Mutation	NA	R1611H	0.41	RNB
UCEC	chr20	63570435	Intron	rs535420171		0.26
UCEC	chr20	63565949	Missense_Mutation	novel	R958I	0.2
UCEC	chr20	63561249	Missense_Mutation	rs779566565	R2327W	0.29
UCEC	chr20	63562627	Silent	novel	R2065R	0.2
UCEC	chr20	63563990	Missense_Mutation	NA	R1611H	0.36	RNB
UCEC	chr20	63564929	Missense_Mutation	rs377142370	R1298H	0.21
UCEC	chr20	63570239	Intron	rs530347157		0.4
UCEC	chr20	63570515	Missense_Mutation	rs371306149	V187I	0.33
UCEC	chr20	63560058	Silent	novel	R2565R	0.27
UCEC	chr20	63561887	Silent	novel	K2209K	0.35
UCEC	chr20	63564136	Silent	novel	Q1562Q	0.45
UCEC	chr20	63566227	Silent	novel	R865R	0.3
UCEC	chr20	63561655	Missense_Mutation	NA	S2261N	0.43
UCEC	chr20	63563046	Missense_Mutation	rs770424257	R1926C	0.22
UCEC	chr20	63561835	Missense_Mutation	novel	D2227N	0.38
UCEC	chr20	63562716	Missense_Mutation	novel	D2036N	0.33
UCEC	chr20	63560250	Silent	rs112998390	A2526A	0.48
UCEC	chr20	63560549	Missense_Mutation	rs138746277	R2477Q	0.48
UCEC	chr20	63561446	Missense_Mutation	rs377628074	R2286Q	0.43
UCEC	chr20	63564728	Missense_Mutation	novel	R1365K	0.55	RNB
UCEC	chr20	63570442	Intron	rs762554959		0.35
UCEC	chr20	63567709	Intron	novel		0.6
UCEC	chr20	63561897	Frame_Shift_Ins	rs776302757	*R2206Pfs42**	0.58
UCEC	chr20	63564724	Silent	rs777924304	C1366C	0.45
UCEC	chr20	63567663	Intron	novel		0.51
UCEC	chr20	63560914	Missense_Mutation	NA	D2388Y	0.16
UCEC	chr20	63569215	Missense_Mutation	NA	N341D	0.17
UCEC	chr20	63566904	Nonsense_Mutation	NA	W818*	0.6
UCEC	chr20	63560799	Missense_Mutation	rs769475511	R2426H	0.15
UCEC	chr20	63567318	Silent	rs370675728	P680P	0.36
UCEC	chr20	63564185	Missense_Mutation	rs116364411	T1546M	0.42	RNB
UCEC	chr20	63560013	Nonsense_Mutation	novel	W2580*	0.36
UCEC	chr20	63559991	Missense_Mutation	rs201718588	V2588I	0.43
UCEC	chr20	63569260	Missense_Mutation	novel	E326Q	0.29
UCEC	chr20	63572890	5'Flank	novel		0.11
UCEC	chr20	63560610	Missense_Mutation	novel	L2457M	0.2
UCEC	chr20	63560907	Missense_Mutation	novel	K2390R	0.21
UCEC	chr20	63561148	Silent	rs374352399	D2360D	0.35
UCEC	chr20	63562705	Silent	novel	T2039T	0.31
UCEC	chr20	63563696	Missense_Mutation	novel	A1709V	0.29
UCEC	chr20	63564670	Silent	novel	V1384V	0.23
UCEC	chr20	63566944	Missense_Mutation	rs192208869	A805V	0.25
UCEC	chr20	63567687	Intron	novel		0.25
UCEC	chr20	63568474	Silent	novel	P538P	0.35
UCEC	chr20	63572948	5'Flank	novel		0.34
UCEC	chr20	63560593	Missense_Mutation	novel	K2462N	0.28
UCEC	chr20	63561664	Missense_Mutation	rs767730930	R2258H	0.35
UCEC	chr20	63563102	Missense_Mutation	rs756827380	P1907L	0.36
UCEC	chr20	63564330	Missense_Mutation	rs767785365	R1498W	0.16	RNB
UCEC	chr20	63568471	Silent	novel	P539P	0.34
UCEC	chr20	63570239	Intron	rs530347157		0.19
UCEC	chr20	63570515	Missense_Mutation	rs371306149	V187I	0.51
UCEC	chr20	63572766	5'Flank	novel		0.32
UCEC	chr20	63563141	Missense_Mutation	novel	G1894V	0.4
UCEC	chr20	63561138	Missense_Mutation	NA	M2364V	0.37
UCEC	chr20	63563872	Silent	novel	C1650C	0.62
UCEC	chr20	63563053	Silent	novel	F1923F	0.44
UCEC	chr20	63563990	Missense_Mutation	NA	R1611H	0.62	RNB
UCEC	chr20	63572789	5'Flank	novel		0.49
UCEC	chr20	63561379	Silent	NA	G2308G	0.36
UCEC	chr20	63564810	Missense_Mutation	rs767271876	R1338C	0.13	RNB
UCEC	chr20	63559281	Missense_Mutation	novel	V2639M	0.34
UCEC	chr20	63562601	Missense_Mutation	novel	G2074D	0.36
UCEC	chr20	63564833	Missense_Mutation	novel	V1330A	0.19
UCEC	chr20	63566050	Silent	rs559661447	C924C	0.1
UCEC	chr20	63560252	Missense_Mutation	rs573248815	A2526T	0.14
UCEC	chr20	63561898	Frame_Shift_Del	rs745497383	*R2206Vfs29**	0.7
UCEC	chr20	63561897	Frame_Shift_Ins	rs776302757	*R2206Pfs42**	0.5
UCEC	chr20	63563069	Missense_Mutation	rs775624299	R1918Q	0.47
UCEC	chr20	63564172	Silent	novel	T1550T	0.4
UCEC	chr20	63565737	Missense_Mutation	rs565301200	A1029T	0.48
UCEC	chr20	63567212	Silent	novel	L716L	0.46
UCEC	chr20	63569562	Missense_Mutation	rs760388183	R225H	0.34
UCEC	chr20	63561897	Frame_Shift_Ins	rs776302757	*R2206Pfs42**	0.6
UCEC	chr20	63559969	Missense_Mutation	novel	N2595S	0.36
UCEC	chr20	63561730	Missense_Mutation	novel	R2236M	0.19
UCEC	chr20	63567275	Missense_Mutation	novel	D695N	0.26
UCEC	chr20	63567519	Silent	rs763459683	T613T	0.27
UCEC	chr20	63565043	Missense_Mutation	novel	R1260Q	0.36
UCEC	chr20	63567042	Silent	rs34124776	P772P	0.43
UCEC	chr20	63561441	Missense_Mutation	rs202204982	R2288W	0.4
UCEC	chr20	63566970	Silent	rs746752815	A796A	0.38
UCEC	chr20	63563713	Silent	rs765414328	I1703I	0.4
UCEC	chr20	63565813	Missense_Mutation	novel	E1003D	0.47
UCEC	chr20	63566221	Missense_Mutation	novel	F867L	0.53
UCEC	chr20	63563712	Missense_Mutation	novel	D1704H	0.42
UCEC	chr20	63570240	Intron	rs548842438		0.23
UCEC	chr20	63569438	Missense_Mutation	novel	K266N	0.17
UCEC	chr20	63560575	Silent	novel	I2468I	0.39
UCEC	chr20	63560917	Missense_Mutation	novel	G2387R	0.21
UCEC	chr20	63569208	Missense_Mutation	rs561374507	R343Q	0.23
UCEC	chr20	63569521	Missense_Mutation	rs751597589	V239M	0.23
UCEC	chr20	63570212	Intron	rs777306947		0.25
UCEC	chr20	63567636	Intron	rs760771051		0.59
UCEC	chr20	63560825	Silent	rs373402164	D2417D	0.26
UCEC	chr20	63562765	Silent	novel	T2019T	0.4
UCEC	chr20	63569208	Missense_Mutation	rs561374507	R343Q	0.2
UCEC	chr20	63567351	Silent	rs547226242	A669A	0.19
UCEC	chr20	63561629	Missense_Mutation	rs201218245	R2270W	0.46
UCEC	chr20	63567284	Silent	novel	L692L	0.35
UCEC	chr20	63564368	Missense_Mutation	novel	C1485Y	0.33	RNB
UCEC	chr20	63561839	Silent	novel	S2225S	0.25
UCEC	chr20	63565661	Missense_Mutation	NA	A1054V	0.75
UCEC	chr20	63562659	Missense_Mutation	rs376190650	R2055C	0.18
UCEC	chr20	63560324	Missense_Mutation	rs377556489	R2502C	0.47
UCEC	chr20	63560627	Missense_Mutation	novel	R2451K	0.39
UCEC	chr20	63561967	Missense_Mutation	rs756836448	V2183M	0.29
UCEC	chr20	63562860	Missense_Mutation	rs200554251	R1988C	0.27
UCEC	chr20	63562961	Missense_Mutation	novel	A1954V	0.36
UCEC	chr20	63565993	Silent	rs748241928	P943P	0.38
UCEC	chr20	63567106	Missense_Mutation	novel	S751I	0.34
UCEC	chr20	63560526	Missense_Mutation	rs368451665	E2485K	0.35
UCEC	chr20	63564415	Silent	novel	P1469P	0.67
UCEC	chr20	63564711	Missense_Mutation	NA	H1371Y	0.45	RNB
UCEC	chr20	63561405	Missense_Mutation	novel	A2300T	0.26
UCS	chr20	63559229	3'UTR	novel		0.3
UCS	chr20	63570529	Missense_Mutation	rs138005803	S182N	0.64
UVM	chr20	63562121	Silent	novel	A2160A	0.55

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LIHC	AMP	0.2892	0.013414
LUAD	AMP	0.3702	8.1427e-15
OV	AMP	0.6339	5.6628e-10
PRAD	AMP	0.0589	0.07085
READ	AMP	0.8667	0.033971
SARC	AMP	0.3074	0.033553
SKCM	AMP	0.4496	0.058021

Survival Analysis

Cancer	P-value	Q-value
THYM	0.034	Kaplan-Meier Survival Analysis
STAD	0.03	Kaplan-Meier Survival Analysis
ACC	0.008	Kaplan-Meier Survival Analysis
SKCM	0.042	Kaplan-Meier Survival Analysis
PRAD	0.044	Kaplan-Meier Survival Analysis
LUSC	0.013	Kaplan-Meier Survival Analysis
TGCT	0.022	Kaplan-Meier Survival Analysis
KIRP	0.024	Kaplan-Meier Survival Analysis
LAML	0.00024	Kaplan-Meier Survival Analysis
UCEC	0.0015	Kaplan-Meier Survival Analysis
CHOL	0.03	Kaplan-Meier Survival Analysis
UVM	0.005	Kaplan-Meier Survival Analysis