Protein ID | Domain | Pfam ID | E-value | Domain number | Total number |
---|---|---|---|---|---|
ENSP00000469684 | zf-CCCH | PF00642.24 | 5.3e-13 | 1 | 1 |
ENSP00000253048 | zf-CCCH | PF00642.24 | 1.7e-12 | 1 | 1 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000595341 | ZC3H4-203 | 431 | - | - | - (aa) | - | - |
ENST00000253048 | ZC3H4-201 | 6119 | XM_005258676 | ENSP00000253048 | 1303 (aa) | XP_005258733 | Q9UPT8 |
ENST00000594019 | ZC3H4-202 | 3259 | - | - | - (aa) | - | - |
ENST00000597069 | ZC3H4-204 | 664 | - | - | - (aa) | - | - |
ENST00000601973 | ZC3H4-205 | 4895 | XM_017026531 | ENSP00000469684 | 910 (aa) | XP_016882020 | M0QY97 |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000130749 | Body Mass Index | 9E-7 | 24861553 |
ENSG00000130749 | Body Mass Index | 5E-15 | 25673413 |
ENSG00000130749 | Body Mass Index | 7E-9 | 25673413 |
ENSG00000130749 | Hormones | 2E-6 | 23251661 |
ENSG00000130749 | Body Mass Index | 3E-10 | 25673413 |
ENSG00000130749 | Waist Circumference | 2E-10 | 25673412 |
ENSG00000130749 | Waist Circumference | 8E-8 | 25673412 |
ENSG00000130749 | Body Mass Index | 2E-12 | 20935630 |
ENSG00000130749 | Body Mass Index | 6E-16 | 25673413 |
ENSG00000130749 | Hip | 2E-8 | 25673412 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000130749 | rs113125564 | 19 | 47092874 | C | Red blood cell count | 27863252 | [0.046-0.08] unit increase | 0.06323484 | EFO_0004305 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Hip circumference | 25673412 | [0.015-0.031] unit increase | 0.023 | EFO_0005093 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index | 24861553 | [0.02-0.047] unit increase | 0.0333 | EFO_0004340 |
ENSG00000130749 | rs3745618 | 19 | 47072459 | A | Obesity-related traits | 23251661 | [NR] pg/mL increase | 0.04 | EFO_0004730 |
ENSG00000130749 | rs2241388 | 19 | 47069730 | C | Hematocrit | 27863252 | [0.019-0.034] unit decrease | 0.02632552 | EFO_0004348 |
ENSG00000130749 | rs2241388 | 19 | 47069730 | C | Hemoglobin concentration | 27863252 | [0.017-0.033] unit decrease | 0.02488376 | EFO_0004509 |
ENSG00000130749 | rs145775149 | 19 | 47103510 | G | Monocyte chemoattractant protein-1 levels | 27989323 | [0.32-0.81] SD units increase | 0.5645 | EFO_0004749 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index | 20935630 | [0.05-0.13] kg/m2 increase | 0.09 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index in physically active individuals | 28448500 | [0.016-0.033] kg/m2 increase | 0.0245 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs2303108 | 19 | 47086638 | ? | Body mass index (joint analysis main effects and physical activity interaction) | 28448500 | EFO_0008002|EFO_0004340 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Waist circumference | 25673412 | [0.018-0.034] unit increase | 0.0259 | EFO_0004342 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Waist circumference | 25673412 | [0.018-0.038] unit increase | 0.0278 | EFO_0004342 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI (adjusted for smoking behaviour) | 28443625 | [0.019-0.033] kg/m2 increase | 0.0259 | EFO_0004318|EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI (adjusted for smoking behaviour) | 28443625 | [0.02-0.039] kg/m2 increase | 0.0292 | EFO_0004318|EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index (joint analysis main effects and smoking interaction) | 28443625 | EFO_0004318|EFO_0004340 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index (joint analysis main effects and smoking interaction) | 28443625 | EFO_0004318|EFO_0004340 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI in smokers | 28443625 | [0.022-0.052] kg/m2 increase | 0.0371 | EFO_0004318|EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI in smokers | 28443625 | [0.029-0.07] kg/m2 increase | 0.0495 | EFO_0004318|EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI in non-smokers | 28443625 | [0.017-0.033] kg/m2 increase | 0.0247 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | BMI in non-smokers | 28443625 | [0.017-0.037] kg/m2 increase | 0.0269 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index | 28448500 | [0.016-0.032] kg/m2 increase | 0.024 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs2303108 | 19 | 47086638 | C | Body mass index | 28448500 | [0.017-0.033] kg/m2 increase | 0.0246 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs2303108 | 19 | 47086638 | C | Body mass index | 28448500 | [0.017-0.038] kg/m2 increase | 0.0272 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs10408163 | 19 | 47093845 | C | Body mass index | 28448500 | [0.017-0.037] kg/m2 increase | 0.0268 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs2303108 | 19 | 47086638 | C | Body mass index in physically active individuals | 28448500 | [0.013-0.031] kg/m2 increase | 0.022 | EFO_0008002|EFO_0004340 |
ENSG00000130749 | rs2303108 | 19 | 47086638 | ? | Body mass index (joint analysis main effects and physical activity interaction) | 28448500 | EFO_0008002|EFO_0004340 | ||
ENSG00000130749 | rs10408163 | 19 | 47093845 | ? | Body mass index (joint analysis main effects and physical activity interaction) | 28448500 | EFO_0008002|EFO_0004340 | ||
ENSG00000130749 | rs10408163 | 19 | 47093845 | ? | Body mass index (joint analysis main effects and physical activity interaction) | 28448500 | EFO_0008002|EFO_0004340 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index | 26426971 | unit increase | 0.02794018 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | G | Body mass index | 30108127 | [NR] unit decrease | 0.026 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Body mass index | 26961502 | [0.02-0.036] unit increase | 0.028 | EFO_0004340 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | ? | Menarche (age at onset) | 30595370 | EFO_0004703 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | ? | Body mass index | 30595370 | EFO_0004340 | ||
ENSG00000130749 | rs12973221 | 19 | 47111403 | ? | Red cell distribution width | 30595370 | EFO_0005192 | ||
ENSG00000130749 | rs17716478 | 19 | 47097336 | ? | Red blood cell count | 30595370 | EFO_0004305 | ||
ENSG00000130749 | rs10408163 | 19 | 47093845 | ? | Lipid traits (pleiotropy) (HIPO component 1) | 30289880 | EFO_0004574|EFO_0004530|EFO_0004611|EFO_0004612 | ||
ENSG00000130749 | rs3810291 | 19 | 47065746 | ? | Fat-free mass | 30593698 | [0.081-0.182] unit increase | 0.13155 | EFO_0004995 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | ? | Fat-free mass | 30593698 | [0.099-0.191] unit increase | 0.14536 | EFO_0004995 |
ENSG00000130749 | rs3810291 | 19 | 47065746 | A | Smoking initiation (ever regular vs never regular) (MTAG) | 30643251 | [0.0043-0.0089] unit increase | 0.00656934 | EFO_0006527 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Paralog | Gene Symbol | Coverage | Identiy |
---|---|---|---|---|---|---|---|
ENSG00000130749 | ZC3H4 | 89 | 41.141 | ENSG00000188177 | ZC3H6 | 56 | 47.685 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000130749 | ZC3H4 | 93 | 59.850 | ENSACAG00000003986 | ZC3H4 | 95 | 62.983 | Anolis_carolinensis |
ENSG00000130749 | ZC3H4 | 100 | 95.939 | ENSANAG00000023963 | ZC3H4 | 100 | 95.939 | Aotus_nancymaae |
ENSG00000130749 | ZC3H4 | 71 | 50.842 | ENSAMXG00000009037 | zc3h4 | 54 | 86.923 | Astyanax_mexicanus |
ENSG00000130749 | ZC3H4 | 99 | 94.175 | ENSBTAG00000009286 | ZC3H4 | 97 | 92.060 | Bos_taurus |
ENSG00000130749 | ZC3H4 | 99 | 96.867 | ENSCJAG00000011601 | ZC3H4 | 100 | 94.950 | Callithrix_jacchus |
ENSG00000130749 | ZC3H4 | 100 | 90.091 | ENSCAFG00000004182 | ZC3H4 | 97 | 89.593 | Canis_familiaris |
ENSG00000130749 | ZC3H4 | 99 | 90.361 | ENSCHIG00000013956 | ZC3H4 | 95 | 90.089 | Capra_hircus |
ENSG00000130749 | ZC3H4 | 87 | 91.852 | ENSTSYG00000000926 | ZC3H4 | 94 | 91.852 | Carlito_syrichta |
ENSG00000130749 | ZC3H4 | 100 | 97.699 | ENSCCAG00000037597 | ZC3H4 | 100 | 97.699 | Cebus_capucinus |
ENSG00000130749 | ZC3H4 | 100 | 97.698 | ENSCATG00000039046 | ZC3H4 | 100 | 97.698 | Cercocebus_atys |
ENSG00000130749 | ZC3H4 | 91 | 97.647 | ENSCLAG00000001032 | ZC3H4 | 84 | 95.388 | Chinchilla_lanigera |
ENSG00000130749 | ZC3H4 | 99 | 98.054 | ENSCSAG00000002989 | ZC3H4 | 99 | 98.479 | Chlorocebus_sabaeus |
ENSG00000130749 | ZC3H4 | 71 | 94.406 | ENSCPBG00000001719 | ZC3H4 | 100 | 70.517 | Chrysemys_picta_bellii |
ENSG00000130749 | ZC3H4 | 99 | 88.652 | ENSCGRG00001016116 | Zc3h4 | 97 | 88.280 | Cricetulus_griseus_chok1gshd |
ENSG00000130749 | ZC3H4 | 99 | 94.928 | ENSDNOG00000003764 | ZC3H4 | 98 | 86.651 | Dasypus_novemcinctus |
ENSG00000130749 | ZC3H4 | 99 | 88.171 | ENSDORG00000002726 | Zc3h4 | 98 | 87.328 | Dipodomys_ordii |
ENSG00000130749 | ZC3H4 | 77 | 96.591 | ENSETEG00000005763 | ZC3H4 | 77 | 96.552 | Echinops_telfairi |
ENSG00000130749 | ZC3H4 | 99 | 94.417 | ENSECAG00000024342 | ZC3H4 | 99 | 93.215 | Equus_caballus |
ENSG00000130749 | ZC3H4 | 86 | 84.298 | ENSEEUG00000000519 | ZC3H4 | 77 | 96.552 | Erinaceus_europaeus |
ENSG00000130749 | ZC3H4 | 99 | 91.667 | ENSFCAG00000004835 | ZC3H4 | 100 | 93.645 | Felis_catus |
ENSG00000130749 | ZC3H4 | 93 | 73.770 | ENSGAGG00000019319 | ZC3H4 | 98 | 68.621 | Gopherus_agassizii |
ENSG00000130749 | ZC3H4 | 100 | 99.693 | ENSGGOG00000013071 | ZC3H4 | 100 | 99.693 | Gorilla_gorilla |
ENSG00000130749 | ZC3H4 | 87 | 97.330 | ENSSTOG00000016249 | ZC3H4 | 83 | 88.583 | Ictidomys_tridecemlineatus |
ENSG00000130749 | ZC3H4 | 95 | 87.863 | ENSJJAG00000019068 | Zc3h4 | 98 | 89.022 | Jaculus_jaculus |
ENSG00000130749 | ZC3H4 | 99 | 95.854 | ENSLAFG00000001586 | ZC3H4 | 100 | 90.666 | Loxodonta_africana |
ENSG00000130749 | ZC3H4 | 100 | 98.465 | ENSMFAG00000041518 | ZC3H4 | 100 | 98.465 | Macaca_fascicularis |
ENSG00000130749 | ZC3H4 | 99 | 97.324 | ENSMLEG00000007946 | ZC3H4 | 100 | 98.479 | Mandrillus_leucophaeus |
ENSG00000130749 | ZC3H4 | 99 | 88.416 | ENSMAUG00000000068 | Zc3h4 | 98 | 88.693 | Mesocricetus_auratus |
ENSG00000130749 | ZC3H4 | 99 | 96.359 | ENSMICG00000008786 | ZC3H4 | 100 | 94.491 | Microcebus_murinus |
ENSG00000130749 | ZC3H4 | 88 | 80.051 | ENSMODG00000008978 | ZC3H4 | 95 | 80.440 | Monodelphis_domestica |
ENSG00000130749 | ZC3H4 | 93 | 90.808 | ENSMUSG00000059273 | Zc3h4 | 98 | 89.014 | Mus_musculus |
ENSG00000130749 | ZC3H4 | 95 | 87.229 | MGP_PahariEiJ_G0021089 | Zc3h4 | 98 | 87.772 | Mus_pahari |
ENSG00000130749 | ZC3H4 | 93 | 88.219 | MGP_SPRETEiJ_G0030312 | Zc3h4 | 98 | 88.329 | Mus_spretus |
ENSG00000130749 | ZC3H4 | 96 | 95.686 | ENSMPUG00000005065 | ZC3H4 | 63 | 82.790 | Mustela_putorius_furo |
ENSG00000130749 | ZC3H4 | 99 | 85.681 | ENSNGAG00000020090 | Zc3h4 | 100 | 85.143 | Nannospalax_galili |
ENSG00000130749 | ZC3H4 | 77 | 82.648 | ENSMEUG00000009167 | ZC3H4 | 80 | 82.134 | Notamacropus_eugenii |
ENSG00000130749 | ZC3H4 | 94 | 90.148 | ENSOPRG00000014889 | ZC3H4 | 88 | 94.721 | Ochotona_princeps |
ENSG00000130749 | ZC3H4 | 92 | 95.614 | ENSODEG00000008320 | ZC3H4 | 100 | 89.218 | Octodon_degus |
ENSG00000130749 | ZC3H4 | 71 | 79.167 | ENSOANG00000001794 | ZC3H4 | 59 | 61.415 | Ornithorhynchus_anatinus |
ENSG00000130749 | ZC3H4 | 99 | 86.248 | ENSOCUG00000026069 | ZC3H4 | 72 | 95.148 | Oryctolagus_cuniculus |
ENSG00000130749 | ZC3H4 | 99 | 96.602 | ENSOGAG00000031123 | ZC3H4 | 100 | 94.870 | Otolemur_garnettii |
ENSG00000130749 | ZC3H4 | 99 | 69.579 | ENSOARG00000010932 | ZC3H4 | 80 | 79.554 | Ovis_aries |
ENSG00000130749 | ZC3H4 | 95 | 91.034 | ENSPPRG00000023272 | ZC3H4 | 95 | 91.599 | Panthera_pardus |
ENSG00000130749 | ZC3H4 | 82 | 98.462 | ENSPTIG00000014229 | ZC3H4 | 93 | 98.305 | Panthera_tigris_altaica |
ENSG00000130749 | ZC3H4 | 100 | 99.463 | ENSPTRG00000011201 | ZC3H4 | 100 | 99.463 | Pan_troglodytes |
ENSG00000130749 | ZC3H4 | 100 | 98.772 | ENSPANG00000021115 | ZC3H4 | 100 | 98.772 | Papio_anubis |
ENSG00000130749 | ZC3H4 | 95 | 79.625 | ENSPSIG00000002241 | ZC3H4 | 99 | 71.223 | Pelodiscus_sinensis |
ENSG00000130749 | ZC3H4 | 93 | 88.643 | ENSPEMG00000009762 | Zc3h4 | 98 | 85.886 | Peromyscus_maniculatus_bairdii |
ENSG00000130749 | ZC3H4 | 92 | 96.683 | ENSPPYG00000010167 | ZC3H4 | 97 | 100.000 | Pongo_abelii |
ENSG00000130749 | ZC3H4 | 75 | 90.142 | ENSPCAG00000014919 | ZC3H4 | 97 | 90.000 | Procavia_capensis |
ENSG00000130749 | ZC3H4 | 99 | 96.602 | ENSPCOG00000017169 | ZC3H4 | 97 | 94.418 | Propithecus_coquereli |
ENSG00000130749 | ZC3H4 | 99 | 93.447 | ENSPVAG00000005687 | ZC3H4 | 89 | 89.301 | Pteropus_vampyrus |
ENSG00000130749 | ZC3H4 | 99 | 86.971 | ENSRNOG00000015229 | Zc3h4 | 78 | 85.559 | Rattus_norvegicus |
ENSG00000130749 | ZC3H4 | 100 | 89.885 | ENSRBIG00000027984 | ZC3H4 | 100 | 93.170 | Rhinopithecus_bieti |
ENSG00000130749 | ZC3H4 | 100 | 97.391 | ENSRROG00000032920 | ZC3H4 | 100 | 97.391 | Rhinopithecus_roxellana |
ENSG00000130749 | ZC3H4 | 89 | 97.170 | ENSSBOG00000030914 | ZC3H4 | 100 | 87.141 | Saimiri_boliviensis_boliviensis |
ENSG00000130749 | ZC3H4 | 88 | 85.443 | ENSSARG00000014146 | ZC3H4 | 76 | 92.647 | Sorex_araneus |
ENSG00000130749 | ZC3H4 | 73 | 95.808 | ENSSSCG00000003110 | ZC3H4 | 57 | 93.703 | Sus_scrofa |
ENSG00000130749 | ZC3H4 | 94 | 93.623 | ENSVVUG00000000208 | ZC3H4 | 78 | 88.470 | Vulpes_vulpes |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | - | ISA | Function |
GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | 21873635. | IBA | Function |
GO:0003700 | DNA-binding transcription factor activity | 21873635. | IBA | Function |
GO:0003723 | RNA binding | 22658674.22681889. | HDA | Function |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005654 | nucleoplasm | - | IDA | Component |
GO:0005829 | cytosol | - | IDA | Component |
GO:0006357 | regulation of transcription by RNA polymerase II | - | IEA | Process |
GO:0045892 | negative regulation of transcription, DNA-templated | 21873635. | IBA | Process |
GO:0046872 | metal ion binding | - | IEA | Function |