EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000130764 (Gene tree)
Gene ID: 57470
Gene Symbol: LRRC47
Alias: KIAA1185|RP1-286D6.3
Full Name: leucine rich repeat containing 47
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 17,947 bases
Position: chr1:3,778,558-3,796,504
Accession: 29207
RBP type: canonical RBP
Summary: (Leucine Rich Repeat Containing 47) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include phenylalanine-tRNA ligase activity. An important paralog of this gene is FARSB.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000367498	B3_4	PF03483.17	5.7e-08	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000378251	LRRC47-201	4310	-	ENSP00000367498	583 (aa)	-	Q8N1G4
ENST00000462356	LRRC47-202	575	-	-	- (aa)	-	-
ENST00000479239	LRRC47-203	434	-	ENSP00000462103	50 (aa)	-	J3KRP5

Gene Model

Click here to download ENSG00000130764's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000130764	Platelet Function Tests	1.4377700E-005	-
ENSG00000130764	Platelet Function Tests	1.5761200E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000130764	rs2996428	1	3780727	T	Red cell distribution width	27863252	[0.03-0.046] unit decrease	0.03845304	EFO_0005192

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000130764's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130764	LRRC47	99	53.899	ENSAPOG00000019553	lrrc47	99	53.979	Acanthochromis_polyacanthus
ENSG00000130764	LRRC47	79	77.706	ENSAMEG00000009152	LRRC47	100	78.139	Ailuropoda_melanoleuca
ENSG00000130764	LRRC47	66	67.183	ENSAPLG00000003167	LRRC47	100	67.183	Anas_platyrhynchos
ENSG00000130764	LRRC47	65	67.192	ENSACAG00000008267	LRRC47	99	67.539	Anolis_carolinensis
ENSG00000130764	LRRC47	100	95.026	ENSANAG00000025576	LRRC47	100	95.026	Aotus_nancymaae
ENSG00000130764	LRRC47	99	84.083	ENSBTAG00000004738	LRRC47	99	83.333	Bos_taurus
ENSG00000130764	LRRC47	99	85.243	ENSCAFG00000019492	LRRC47	99	84.192	Canis_familiaris
ENSG00000130764	LRRC47	100	85.077	ENSCAFG00020009667	LRRC47	100	84.391	Canis_lupus_dingo
ENSG00000130764	LRRC47	99	84.602	ENSCHIG00000022607	LRRC47	99	82.990	Capra_hircus
ENSG00000130764	LRRC47	96	93.178	ENSTSYG00000009326	LRRC47	96	93.178	Carlito_syrichta
ENSG00000130764	LRRC47	65	83.862	ENSCAPG00000016517	LRRC47	100	83.598	Cavia_aperea
ENSG00000130764	LRRC47	100	87.307	ENSCPOG00000014931	LRRC47	96	87.479	Cavia_porcellus
ENSG00000130764	LRRC47	100	95.883	ENSCCAG00000024895	LRRC47	100	95.883	Cebus_capucinus
ENSG00000130764	LRRC47	100	98.456	ENSCATG00000029337	LRRC47	100	98.456	Cercocebus_atys
ENSG00000130764	LRRC47	100	88.679	ENSCLAG00000006093	LRRC47	100	89.194	Chinchilla_lanigera
ENSG00000130764	LRRC47	100	98.799	ENSCSAG00000000727	LRRC47	100	98.799	Chlorocebus_sabaeus
ENSG00000130764	LRRC47	99	62.563	ENSCPBG00000019404	LRRC47	98	62.563	Chrysemys_picta_bellii
ENSG00000130764	LRRC47	79	96.095	ENSCANG00000030701	LRRC47	96	96.095	Colobus_angolensis_palliatus
ENSG00000130764	LRRC47	99	84.896	ENSCGRG00001015159	Lrrc47	90	84.337	Cricetulus_griseus_chok1gshd
ENSG00000130764	LRRC47	65	77.165	ENSCGRG00000017336	Lrrc47	100	76.984	Cricetulus_griseus_crigri
ENSG00000130764	LRRC47	99	52.000	ENSCSEG00000006217	lrrc47	95	53.217	Cynoglossus_semilaevis
ENSG00000130764	LRRC47	65	83.554	ENSDORG00000016594	Lrrc47	99	83.554	Dipodomys_ordii
ENSG00000130764	LRRC47	100	87.842	ENSEASG00005021788	LRRC47	100	87.329	Equus_asinus_asinus
ENSG00000130764	LRRC47	99	88.428	ENSECAG00000022472	LRRC47	91	88.527	Equus_caballus
ENSG00000130764	LRRC47	99	51.078	ENSELUG00000017544	lrrc47	98	52.115	Esox_lucius
ENSG00000130764	LRRC47	94	86.679	ENSFCAG00000011632	LRRC47	97	85.870	Felis_catus
ENSG00000130764	LRRC47	78	62.555	ENSFALG00000009631	LRRC47	99	64.009	Ficedula_albicollis
ENSG00000130764	LRRC47	99	51.646	ENSGMOG00000015674	lrrc47	99	51.646	Gadus_morhua
ENSG00000130764	LRRC47	98	63.212	ENSGALG00000050995	LRRC47	99	64.421	Gallus_gallus
ENSG00000130764	LRRC47	99	53.043	ENSGACG00000005550	lrrc47	99	53.043	Gasterosteus_aculeatus
ENSG00000130764	LRRC47	100	64.060	ENSGAGG00000022584	LRRC47	99	64.060	Gopherus_agassizii
ENSG00000130764	LRRC47	100	99.485	ENSGGOG00000015571	LRRC47	100	99.485	Gorilla_gorilla
ENSG00000130764	LRRC47	100	87.136	ENSHGLG00000018278	LRRC47	96	87.136	Heterocephalus_glaber_female
ENSG00000130764	LRRC47	69	83.704	ENSHGLG00100008507	LRRC47	100	83.704	Heterocephalus_glaber_male
ENSG00000130764	LRRC47	99	53.993	ENSHCOG00000006348	lrrc47	97	54.593	Hippocampus_comes
ENSG00000130764	LRRC47	100	90.460	ENSSTOG00000027559	LRRC47	100	91.312	Ictidomys_tridecemlineatus
ENSG00000130764	LRRC47	99	89.081	ENSJJAG00000017474	Lrrc47	97	89.194	Jaculus_jaculus
ENSG00000130764	LRRC47	99	53.460	ENSKMAG00000003414	lrrc47	99	53.287	Kryptolebias_marmoratus
ENSG00000130764	LRRC47	100	86.964	ENSLAFG00000011657	LRRC47	99	86.964	Loxodonta_africana
ENSG00000130764	LRRC47	100	64.677	ENSMFAG00000045730	LRRC47	82	99.029	Macaca_fascicularis
ENSG00000130764	LRRC47	99	98.282	ENSMNEG00000042488	LRRC47	99	98.282	Macaca_nemestrina
ENSG00000130764	LRRC47	77	95.787	ENSMLEG00000043735	LRRC47	91	95.787	Mandrillus_leucophaeus
ENSG00000130764	LRRC47	99	86.183	ENSMAUG00000021337	Lrrc47	98	85.838	Mesocricetus_auratus
ENSG00000130764	LRRC47	100	91.424	ENSMICG00000026816	LRRC47	100	91.767	Microcebus_murinus
ENSG00000130764	LRRC47	100	84.734	ENSMOCG00000021279	Lrrc47	100	86.449	Microtus_ochrogaster
ENSG00000130764	LRRC47	99	52.431	ENSMMOG00000017007	lrrc47	99	52.431	Mola_mola
ENSG00000130764	LRRC47	99	74.306	ENSMODG00000006554	LRRC47	100	70.698	Monodelphis_domestica
ENSG00000130764	LRRC47	99	86.851	MGP_CAROLIEiJ_G0026864	Lrrc47	99	86.082	Mus_caroli
ENSG00000130764	LRRC47	99	86.678	ENSMUSG00000029028	Lrrc47	99	85.911	Mus_musculus
ENSG00000130764	LRRC47	99	84.055	MGP_PahariEiJ_G0029212	Lrrc47	99	86.082	Mus_pahari
ENSG00000130764	LRRC47	99	86.851	MGP_SPRETEiJ_G0027857	Lrrc47	99	86.082	Mus_spretus
ENSG00000130764	LRRC47	65	79.947	ENSMPUG00000007321	LRRC47	75	80.211	Mustela_putorius_furo
ENSG00000130764	LRRC47	98	86.760	ENSNGAG00000022153	Lrrc47	99	87.993	Nannospalax_galili
ENSG00000130764	LRRC47	100	95.197	ENSNLEG00000008131	LRRC47	100	95.197	Nomascus_leucogenys
ENSG00000130764	LRRC47	84	85.540	ENSODEG00000010882	LRRC47	93	85.540	Octodon_degus
ENSG00000130764	LRRC47	96	54.448	ENSORLG00000002532	lrrc47	99	54.480	Oryzias_latipes
ENSG00000130764	LRRC47	99	54.483	ENSORLG00020019601	lrrc47	99	54.514	Oryzias_latipes_hni
ENSG00000130764	LRRC47	99	53.966	ENSORLG00015014040	lrrc47	99	53.993	Oryzias_latipes_hsok
ENSG00000130764	LRRC47	99	54.138	ENSOMEG00000008989	lrrc47	99	54.073	Oryzias_melastigma
ENSG00000130764	LRRC47	100	90.566	ENSOGAG00000001553	LRRC47	100	90.566	Otolemur_garnettii
ENSG00000130764	LRRC47	99	80.796	ENSOARG00000015290	LRRC47	99	80.069	Ovis_aries
ENSG00000130764	LRRC47	98	99.063	ENSPPAG00000036370	-	100	99.063	Pan_paniscus
ENSG00000130764	LRRC47	99	85.986	ENSPPRG00000005261	LRRC47	99	85.223	Panthera_pardus
ENSG00000130764	LRRC47	100	99.314	ENSPTRG00000000068	LRRC47	100	99.314	Pan_troglodytes
ENSG00000130764	LRRC47	100	98.799	ENSPANG00000012437	LRRC47	100	98.799	Papio_anubis
ENSG00000130764	LRRC47	65	67.454	ENSPSIG00000004196	LRRC47	100	67.454	Pelodiscus_sinensis
ENSG00000130764	LRRC47	65	81.217	ENSPEMG00000021068	Lrrc47	100	80.952	Peromyscus_maniculatus_bairdii
ENSG00000130764	LRRC47	98	76.307	ENSPCIG00000003638	LRRC47	100	75.809	Phascolarctos_cinereus
ENSG00000130764	LRRC47	93	55.311	ENSPFOG00000000992	lrrc47	94	55.311	Poecilia_formosa
ENSG00000130764	LRRC47	99	55.556	ENSPLAG00000008077	lrrc47	99	55.556	Poecilia_latipinna
ENSG00000130764	LRRC47	99	55.208	ENSPMEG00000007367	lrrc47	99	55.208	Poecilia_mexicana
ENSG00000130764	LRRC47	100	99.142	ENSPPYG00000001960	LRRC47	100	99.142	Pongo_abelii
ENSG00000130764	LRRC47	99	91.869	ENSPCOG00000019161	LRRC47	99	92.096	Propithecus_coquereli
ENSG00000130764	LRRC47	100	85.616	ENSPVAG00000009839	LRRC47	100	84.563	Pteropus_vampyrus
ENSG00000130764	LRRC47	100	55.043	ENSPNAG00000017982	lrrc47	100	54.872	Pygocentrus_nattereri
ENSG00000130764	LRRC47	99	85.739	ENSRNOG00000024796	Lrrc47	99	86.770	Rattus_norvegicus
ENSG00000130764	LRRC47	100	98.113	ENSRBIG00000019437	LRRC47	100	98.113	Rhinopithecus_bieti
ENSG00000130764	LRRC47	100	98.113	ENSRROG00000043182	LRRC47	100	98.113	Rhinopithecus_roxellana
ENSG00000130764	LRRC47	81	92.017	ENSSBOG00000026334	LRRC47	97	92.211	Saimiri_boliviensis_boliviensis
ENSG00000130764	LRRC47	98	62.436	ENSSHAG00000007360	LRRC47	100	62.121	Sarcophilus_harrisii
ENSG00000130764	LRRC47	99	54.435	ENSSMAG00000009344	lrrc47	99	54.688	Scophthalmus_maximus
ENSG00000130764	LRRC47	99	52.850	ENSSDUG00000014618	lrrc47	99	53.472	Seriola_dumerili
ENSG00000130764	LRRC47	99	53.541	ENSSLDG00000018908	lrrc47	99	53.646	Seriola_lalandi_dorsalis
ENSG00000130764	LRRC47	99	62.373	ENSSPUG00000010277	LRRC47	99	62.081	Sphenodon_punctatus
ENSG00000130764	LRRC47	99	55.806	ENSSPAG00000005188	lrrc47	99	55.806	Stegastes_partitus
ENSG00000130764	LRRC47	99	83.849	ENSSSCG00000039516	LRRC47	99	83.333	Sus_scrofa
ENSG00000130764	LRRC47	70	65.281	ENSTGUG00000002737	LRRC47	99	64.059	Taeniopygia_guttata
ENSG00000130764	LRRC47	99	52.860	ENSTRUG00000017696	lrrc47	99	52.431	Takifugu_rubripes
ENSG00000130764	LRRC47	99	52.768	ENSTNIG00000010923	lrrc47	99	51.993	Tetraodon_nigroviridis
ENSG00000130764	LRRC47	100	84.075	ENSTTRG00000011751	LRRC47	100	83.904	Tursiops_truncatus
ENSG00000130764	LRRC47	88	83.658	ENSUAMG00000012080	LRRC47	97	84.047	Ursus_americanus
ENSG00000130764	LRRC47	66	78.796	ENSUMAG00000010781	LRRC47	81	79.319	Ursus_maritimus
ENSG00000130764	LRRC47	99	77.250	ENSVVUG00000027118	LRRC47	99	75.214	Vulpes_vulpes
ENSG00000130764	LRRC47	99	61.235	ENSXETG00000006029	lrrc47	99	61.235	Xenopus_tropicalis
ENSG00000130764	LRRC47	98	55.478	ENSXCOG00000002813	lrrc47	98	54.957	Xiphophorus_couchianus
ENSG00000130764	LRRC47	99	54.783	ENSXMAG00000019386	lrrc47	99	55.208	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0004826	phenylalanine-tRNA ligase activity	21873635.	IBA	Function
GO:0005515	protein binding	22190034.	IPI	Function