EuRBPDB

Description

Ensembl ID: ENSG00000130813 (Gene tree)
Gene ID: 55337
Gene Symbol: C19orf66
Alias: FLJ11286|RyDEN|IRAV|SFL|RYDEN
Full Name: chromosome 19 open reading frame 66
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 7,134 bases
Position: chr19:10,086,119-10,093,252
Accession: 25649
RBP type: non-canonical RBP
Summary: (Chromosome 19 Open Reading Frame 66) is a Protein Coding gene. Diseases associated with C19orf66 include Dengue Virus.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
26735137	Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication.	PLoS Pathog	2016 Jan 6	Suzuki Y	doi: 10.1371/journal.ppat.1005357

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000586730	C19orf66-204	1655	-	-	- (aa)	-	-
ENST00000587609	C19orf66-206	399	-	-	- (aa)	-	-
ENST00000587710	C19orf66-207	808	-	ENSP00000466633	127 (aa)	-	K7EMS9
ENST00000591813	C19orf66-209	1481	-	ENSP00000467182	255 (aa)	-	Q9NUL5
ENST00000592551	C19orf66-210	1461	-	-	- (aa)	-	-
ENST00000586889	C19orf66-205	550	-	ENSP00000466217	77 (aa)	-	K7ELT7
ENST00000397881	C19orf66-202	2140	XM_011528121	ENSP00000380978	240 (aa)	XP_011526423	Q9NUL5
ENST00000590378	C19orf66-208	621	-	ENSP00000466550	71 (aa)	-	K7EML3
ENST00000253110	C19orf66-201	2117	-	ENSP00000253110	291 (aa)	-	Q9NUL5
ENST00000585919	C19orf66-203	2079	-	-	- (aa)	-	-
ENST00000593131	C19orf66-211	565	-	ENSP00000467167	143 (aa)	-	K7EP02

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000130813	Thyrotropin	4.4200000E-005	-
ENSG00000130813	Longevity	2E-6	27015805

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130813	C19orf66	100	95.533	ENSMUSG00000038884	A230050P20Rik	100	93.471	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	26735137.	IDA	Function
GO:0005515	protein binding	21044950.25416956.25814554.26735137.	IPI	Function
GO:0005634	nucleus	26735137.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	26735137.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0034340	response to type I interferon	26735137.	IDA	Process
GO:0034341	response to interferon-gamma	26735137.	IDA	Process
GO:0034342	response to type III interferon	26735137.	IDA	Process
GO:0045071	negative regulation of viral genome replication	26735137.	IMP	Process
GO:0051607	defense response to virus	26735137.	IDA	Process