EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000130935 (Gene tree)
Gene ID: 25926
Gene Symbol: NOL11
Alias: DKFZP586L0724
Full Name: nucleolar protein 11
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 26,699 bases
Position: chr17:67,717,833-67,744,531
Accession: 24557
RBP type: canonical RBP
Summary: (Nucleolar Protein 11) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000464015	NUC205	PF08168.11	2.9e-25	1	1
ENSP00000253247	NUC205	PF08168.11	9.2e-25	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000581375	NOL11-206	2448	-	ENSP00000463219	169 (aa)	-	Q9H8H0
ENST00000253247	NOL11-201	2947	-	ENSP00000253247	719 (aa)	-	Q9H8H0
ENST00000580914	NOL11-204	654	-	-	- (aa)	-	-
ENST00000583108	NOL11-209	2071	-	-	- (aa)	-	-
ENST00000581966	NOL11-207	476	-	-	- (aa)	-	-
ENST00000577687	NOL11-202	560	-	-	- (aa)	-	-
ENST00000581106	NOL11-205	584	-	ENSP00000463662	189 (aa)	-	J3QLQ6
ENST00000583021	NOL11-208	443	-	ENSP00000463248	85 (aa)	-	J3QKV1
ENST00000584032	NOL11-210	612	-	-	- (aa)	-	-
ENST00000580833	NOL11-203	815	-	ENSP00000464015	271 (aa)	-	J3QR28
ENST00000584942	NOL11-211	552	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000130935's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000130935	rs758468472	17	67718094	G	Tooth agenesis (maxillary second premolars)	29364747	[8.47-88.7]	27.4	EFO_0005410

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000130935's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000130935	NOL11	91	89.610	ENSAMEG00000018406	NOL11	100	83.538	Ailuropoda_melanoleuca
ENSG00000130935	NOL11	93	55.474	ENSAPLG00000006588	NOL11	100	55.474	Anas_platyrhynchos
ENSG00000130935	NOL11	100	55.556	ENSACAG00000000253	NOL11	99	53.562	Anolis_carolinensis
ENSG00000130935	NOL11	100	92.907	ENSANAG00000032675	NOL11	100	92.907	Aotus_nancymaae
ENSG00000130935	NOL11	100	84.284	ENSBTAG00000015951	NOL11	100	84.284	Bos_taurus
ENSG00000130935	NOL11	100	93.046	ENSCJAG00000008775	NOL11	100	93.046	Callithrix_jacchus
ENSG00000130935	NOL11	100	84.840	ENSCAFG00000011500	NOL11	100	84.840	Canis_familiaris
ENSG00000130935	NOL11	100	84.979	ENSCAFG00020026235	NOL11	100	84.979	Canis_lupus_dingo
ENSG00000130935	NOL11	100	84.701	ENSCHIG00000025602	NOL11	100	84.701	Capra_hircus
ENSG00000130935	NOL11	100	81.806	ENSTSYG00000004693	NOL11	100	81.806	Carlito_syrichta
ENSG00000130935	NOL11	99	56.944	ENSCAPG00000009765	NOL11	100	61.905	Cavia_aperea
ENSG00000130935	NOL11	100	80.525	ENSCPOG00000011415	NOL11	100	80.525	Cavia_porcellus
ENSG00000130935	NOL11	100	92.907	ENSCCAG00000021153	NOL11	100	92.907	Cebus_capucinus
ENSG00000130935	NOL11	100	83.310	ENSCATG00000036259	-	100	83.310	Cercocebus_atys
ENSG00000130935	NOL11	100	95.652	ENSCATG00000026067	NOL11	100	93.741	Cercocebus_atys
ENSG00000130935	NOL11	100	78.581	ENSCLAG00000002744	NOL11	100	78.581	Chinchilla_lanigera
ENSG00000130935	NOL11	100	96.940	ENSCSAG00000004179	NOL11	100	96.940	Chlorocebus_sabaeus
ENSG00000130935	NOL11	76	77.711	ENSCHOG00000011318	NOL11	76	77.711	Choloepus_hoffmanni
ENSG00000130935	NOL11	99	60.733	ENSCPBG00000009509	NOL11	99	60.246	Chrysemys_picta_bellii
ENSG00000130935	NOL11	89	87.333	ENSCANG00000031851	-	100	74.548	Colobus_angolensis_palliatus
ENSG00000130935	NOL11	100	89.847	ENSCANG00000028145	NOL11	100	89.847	Colobus_angolensis_palliatus
ENSG00000130935	NOL11	100	79.477	ENSCGRG00001024010	Nol11	100	79.477	Cricetulus_griseus_chok1gshd
ENSG00000130935	NOL11	100	79.477	ENSCGRG00000012819	Nol11	100	79.477	Cricetulus_griseus_crigri
ENSG00000130935	NOL11	100	79.391	ENSDNOG00000013861	NOL11	100	79.391	Dasypus_novemcinctus
ENSG00000130935	NOL11	82	71.942	ENSETEG00000009762	-	82	67.778	Echinops_telfairi
ENSG00000130935	NOL11	91	93.506	ENSEASG00005015876	NOL11	98	85.838	Equus_asinus_asinus
ENSG00000130935	NOL11	100	85.257	ENSECAG00000008252	NOL11	100	85.257	Equus_caballus
ENSG00000130935	NOL11	74	92.105	ENSEEUG00000000522	-	73	92.105	Erinaceus_europaeus
ENSG00000130935	NOL11	100	82.361	ENSFCAG00000026399	NOL11	100	82.361	Felis_catus
ENSG00000130935	NOL11	100	81.919	ENSFDAG00000005726	NOL11	100	81.919	Fukomys_damarensis
ENSG00000130935	NOL11	100	57.653	ENSGALG00000003650	NOL11	100	55.224	Gallus_gallus
ENSG00000130935	NOL11	100	83.310	ENSGGOG00000022151	-	100	83.310	Gorilla_gorilla
ENSG00000130935	NOL11	100	100.000	ENSGGOG00000011155	NOL11	100	99.026	Gorilla_gorilla
ENSG00000130935	NOL11	100	82.337	ENSHGLG00000003039	NOL11	100	82.337	Heterocephalus_glaber_female
ENSG00000130935	NOL11	100	82.337	ENSHGLG00100002623	NOL11	100	82.337	Heterocephalus_glaber_male
ENSG00000130935	NOL11	100	82.615	ENSSTOG00000003704	NOL11	100	82.615	Ictidomys_tridecemlineatus
ENSG00000130935	NOL11	100	74.689	ENSJJAG00000019386	Nol11	100	74.689	Jaculus_jaculus
ENSG00000130935	NOL11	91	67.308	ENSLACG00000013558	NOL11	100	47.019	Latimeria_chalumnae
ENSG00000130935	NOL11	100	82.337	ENSLAFG00000002021	NOL11	100	82.337	Loxodonta_africana
ENSG00000130935	NOL11	100	96.801	ENSMFAG00000030117	NOL11	100	96.801	Macaca_fascicularis
ENSG00000130935	NOL11	100	95.652	ENSMMUG00000002414	NOL11	100	93.880	Macaca_mulatta
ENSG00000130935	NOL11	100	95.652	ENSMNEG00000029864	NOL11	100	94.159	Macaca_nemestrina
ENSG00000130935	NOL11	100	84.562	ENSMNEG00000032718	-	100	84.562	Macaca_nemestrina
ENSG00000130935	NOL11	100	84.284	ENSMLEG00000028816	-	100	84.284	Mandrillus_leucophaeus
ENSG00000130935	NOL11	100	94.904	ENSMLEG00000024403	NOL11	100	93.241	Mandrillus_leucophaeus
ENSG00000130935	NOL11	100	50.323	ENSMGAG00000007511	NOL11	100	55.313	Meleagris_gallopavo
ENSG00000130935	NOL11	91	88.889	ENSMAUG00000009375	Nol11	100	79.614	Mesocricetus_auratus
ENSG00000130935	NOL11	99	88.451	ENSMICG00000017576	NOL11	96	88.451	Microcebus_murinus
ENSG00000130935	NOL11	91	85.065	ENSMOCG00000012117	Nol11	100	75.552	Microtus_ochrogaster
ENSG00000130935	NOL11	91	81.699	ENSMODG00000003956	NOL11	100	67.263	Monodelphis_domestica
ENSG00000130935	NOL11	100	76.033	MGP_CAROLIEiJ_G0017334	Nol11	100	76.033	Mus_caroli
ENSG00000130935	NOL11	100	76.033	ENSMUSG00000018433	Nol11	100	76.033	Mus_musculus
ENSG00000130935	NOL11	100	75.482	MGP_SPRETEiJ_G0018178	Nol11	100	75.482	Mus_spretus
ENSG00000130935	NOL11	100	82.893	ENSMPUG00000014685	NOL11	100	82.893	Mustela_putorius_furo
ENSG00000130935	NOL11	100	84.327	ENSMLUG00000013484	-	100	84.327	Myotis_lucifugus
ENSG00000130935	NOL11	90	79.104	ENSMLUG00000024296	-	100	73.673	Myotis_lucifugus
ENSG00000130935	NOL11	91	89.542	ENSNGAG00000016886	Nol11	100	77.608	Nannospalax_galili
ENSG00000130935	NOL11	100	98.261	ENSNLEG00000001436	NOL11	100	97.775	Nomascus_leucogenys
ENSG00000130935	NOL11	100	87.344	ENSNLEG00000013566	-	100	87.065	Nomascus_leucogenys
ENSG00000130935	NOL11	61	55.556	ENSMEUG00000003244	-	66	62.069	Notamacropus_eugenii
ENSG00000130935	NOL11	100	67.196	ENSOPRG00000008767	NOL11	74	89.313	Ochotona_princeps
ENSG00000130935	NOL11	89	80.795	ENSODEG00000007922	NOL11	100	63.282	Octodon_degus
ENSG00000130935	NOL11	93	59.733	ENSOANG00000008052	NOL11	100	59.733	Ornithorhynchus_anatinus
ENSG00000130935	NOL11	100	83.449	ENSOCUG00000015612	NOL11	100	83.449	Oryctolagus_cuniculus
ENSG00000130935	NOL11	91	92.157	ENSOGAG00000000668	NOL11	100	84.818	Otolemur_garnettii
ENSG00000130935	NOL11	100	84.701	ENSOARG00000015771	NOL11	100	84.701	Ovis_aries
ENSG00000130935	NOL11	100	83.310	ENSPPAG00000043892	-	100	83.310	Pan_paniscus
ENSG00000130935	NOL11	100	100.000	ENSPPAG00000032763	NOL11	100	99.305	Pan_paniscus
ENSG00000130935	NOL11	100	82.361	ENSPPRG00000025048	NOL11	100	82.361	Panthera_pardus
ENSG00000130935	NOL11	100	82.361	ENSPTIG00000018044	NOL11	100	82.361	Panthera_tigris_altaica
ENSG00000130935	NOL11	100	100.000	ENSPTRG00000009566	NOL11	100	99.861	Pan_troglodytes
ENSG00000130935	NOL11	100	83.171	ENSPTRG00000043276	-	100	83.171	Pan_troglodytes
ENSG00000130935	NOL11	100	96.523	ENSPANG00000020519	NOL11	100	96.523	Papio_anubis
ENSG00000130935	NOL11	100	60.938	ENSPSIG00000007198	NOL11	99	58.936	Pelodiscus_sinensis
ENSG00000130935	NOL11	91	85.714	ENSPEMG00000006648	-	100	76.446	Peromyscus_maniculatus_bairdii
ENSG00000130935	NOL11	100	66.162	ENSPEMG00000014781	-	100	66.162	Peromyscus_maniculatus_bairdii
ENSG00000130935	NOL11	91	81.699	ENSPCIG00000019293	NOL11	100	67.950	Phascolarctos_cinereus
ENSG00000130935	NOL11	100	98.261	ENSPPYG00000008567	NOL11	100	97.636	Pongo_abelii
ENSG00000130935	NOL11	85	85.106	ENSPCAG00000009216	NOL11	85	85.106	Procavia_capensis
ENSG00000130935	NOL11	100	81.481	ENSPVAG00000016037	NOL11	84	88.319	Pteropus_vampyrus
ENSG00000130935	NOL11	91	85.621	ENSRNOG00000052934	Nol11	100	73.655	Rattus_norvegicus
ENSG00000130935	NOL11	95	81.912	ENSRBIG00000039495	-	94	81.912	Rhinopithecus_bieti
ENSG00000130935	NOL11	100	96.384	ENSRROG00000002781	NOL11	100	96.384	Rhinopithecus_roxellana
ENSG00000130935	NOL11	100	92.490	ENSSBOG00000036070	NOL11	100	92.490	Saimiri_boliviensis_boliviensis
ENSG00000130935	NOL11	91	82.353	ENSSHAG00000008470	NOL11	99	67.822	Sarcophilus_harrisii
ENSG00000130935	NOL11	100	84.701	ENSSSCG00000017275	NOL11	100	84.701	Sus_scrofa
ENSG00000130935	NOL11	91	92.810	ENSTBEG00000007114	-	82	84.211	Tupaia_belangeri
ENSG00000130935	NOL11	100	85.278	ENSTTRG00000013960	NOL11	100	85.278	Tursiops_truncatus
ENSG00000130935	NOL11	100	84.284	ENSUAMG00000028064	NOL11	100	84.284	Ursus_americanus
ENSG00000130935	NOL11	100	84.423	ENSUMAG00000018710	NOL11	100	84.423	Ursus_maritimus
ENSG00000130935	NOL11	100	82.361	ENSVPAG00000001852	NOL11	100	82.361	Vicugna_pacos
ENSG00000130935	NOL11	100	82.011	ENSVVUG00000006471	NOL11	100	80.807	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	22916032.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	22916032.	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0030490	maturation of SSU-rRNA	22916032.	IMP	Process
GO:0034455	t-UTP complex	22916032.	IDA	Component
GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	22916032.	IMP	Process