EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000131043 (Gene tree)
Gene ID: 25980
Gene Symbol: AAR2
Alias: bA234K24.2|C20orf4
Full Name: AAR2 splicing factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 34,502 bases
Position: chr20:36,236,417-36,270,918
Accession: 15886
RBP type: canonical RBP
Summary: This gene encodes the homolog of the yeast A1-alpha2 repressin protein that is involved in mRNA splicing. Alternately spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000313674	AAR2	PF05282.11	2.8e-106	1	1
ENSP00000363043	AAR2	PF05282.11	2.8e-106	1	1
ENSP00000380455	AAR2	PF05282.11	2.8e-98	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000397286	AAR2-203	1466	-	ENSP00000380455	398 (aa)	-	A2A2Q9
ENST00000320849	AAR2-201	2430	XM_011528762	ENSP00000313674	384 (aa)	XP_011527064	Q9Y312
ENST00000373932	AAR2-202	2689	XM_006723770	ENSP00000363043	384 (aa)	XP_006723833	Q9Y312

Gene Model

Click here to download ENSG00000131043's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000131043	Platelet Function Tests	3.4120300E-005	-
ENSG00000131043	Motor Activity	4E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000131043	rs2425192	20	36242663	A	Low tan response	29739929	[0.15-0.39] unit increase	0.269	EFO_0004279

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000131043's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000131043	AAR2	99	61.257	ENSAPOG00000010290	aar2	99	61.097	Acanthochromis_polyacanthus
ENSG00000131043	AAR2	100	91.667	ENSAMEG00000010052	AAR2	100	91.667	Ailuropoda_melanoleuca
ENSG00000131043	AAR2	99	62.730	ENSACIG00000019823	aar2	99	62.730	Amphilophus_citrinellus
ENSG00000131043	AAR2	98	61.842	ENSAOCG00000013023	aar2	98	61.518	Amphiprion_ocellaris
ENSG00000131043	AAR2	98	62.105	ENSAPEG00000008277	aar2	98	61.780	Amphiprion_percula
ENSG00000131043	AAR2	99	60.471	ENSATEG00000005558	aar2	98	60.471	Anabas_testudineus
ENSG00000131043	AAR2	89	67.251	ENSAPLG00000012763	AAR2	99	67.251	Anas_platyrhynchos
ENSG00000131043	AAR2	100	75.781	ENSACAG00000001819	AAR2	100	75.781	Anolis_carolinensis
ENSG00000131043	AAR2	100	95.833	ENSANAG00000029758	AAR2	100	95.833	Aotus_nancymaae
ENSG00000131043	AAR2	99	61.155	ENSACLG00000025925	aar2	99	60.995	Astatotilapia_calliptera
ENSG00000131043	AAR2	99	61.458	ENSAMXG00000017993	aar2	96	62.240	Astyanax_mexicanus
ENSG00000131043	AAR2	100	91.667	ENSBTAG00000001645	AAR2	100	91.667	Bos_taurus
ENSG00000131043	AAR2	93	33.871	WBGene00008639	F10B5.2	98	33.871	Caenorhabditis_elegans
ENSG00000131043	AAR2	100	96.354	ENSCJAG00000017423	AAR2	100	96.354	Callithrix_jacchus
ENSG00000131043	AAR2	100	93.750	ENSCAFG00000008435	AAR2	100	93.750	Canis_familiaris
ENSG00000131043	AAR2	100	93.750	ENSCAFG00020005856	AAR2	100	93.750	Canis_lupus_dingo
ENSG00000131043	AAR2	100	92.188	ENSCHIG00000021208	AAR2	100	92.188	Capra_hircus
ENSG00000131043	AAR2	99	93.995	ENSTSYG00000013684	AAR2	99	93.995	Carlito_syrichta
ENSG00000131043	AAR2	100	86.458	ENSCAPG00000009227	AAR2	100	86.458	Cavia_aperea
ENSG00000131043	AAR2	100	91.927	ENSCPOG00000012252	AAR2	100	91.927	Cavia_porcellus
ENSG00000131043	AAR2	100	95.573	ENSCCAG00000037250	AAR2	100	95.573	Cebus_capucinus
ENSG00000131043	AAR2	100	98.177	ENSCATG00000031041	AAR2	100	98.177	Cercocebus_atys
ENSG00000131043	AAR2	100	92.188	ENSCLAG00000017214	AAR2	100	92.188	Chinchilla_lanigera
ENSG00000131043	AAR2	100	98.177	ENSCSAG00000010038	AAR2	100	98.177	Chlorocebus_sabaeus
ENSG00000131043	AAR2	66	90.873	ENSCHOG00000013287	AAR2	100	90.873	Choloepus_hoffmanni
ENSG00000131043	AAR2	99	77.690	ENSCPBG00000018203	AAR2	99	77.690	Chrysemys_picta_bellii
ENSG00000131043	AAR2	96	44.324	ENSCING00000007482	-	100	44.324	Ciona_intestinalis
ENSG00000131043	AAR2	100	98.177	ENSCANG00000007708	AAR2	100	98.177	Colobus_angolensis_palliatus
ENSG00000131043	AAR2	100	92.448	ENSCGRG00001011146	Aar2	100	92.448	Cricetulus_griseus_chok1gshd
ENSG00000131043	AAR2	100	92.448	ENSCGRG00000010294	Aar2	100	92.448	Cricetulus_griseus_crigri
ENSG00000131043	AAR2	97	58.245	ENSCSEG00000020991	aar2	99	58.245	Cynoglossus_semilaevis
ENSG00000131043	AAR2	99	59.948	ENSCVAG00000010492	aar2	99	60.000	Cyprinodon_variegatus
ENSG00000131043	AAR2	99	61.518	ENSDARG00000018658	aar2	99	61.518	Danio_rerio
ENSG00000131043	AAR2	95	55.616	ENSDNOG00000033243	-	98	55.616	Dasypus_novemcinctus
ENSG00000131043	AAR2	99	94.241	ENSDORG00000026983	Aar2	99	94.241	Dipodomys_ordii
ENSG00000131043	AAR2	99	33.167	FBgn0038590	CG12320	99	33.167	Drosophila_melanogaster
ENSG00000131043	AAR2	100	88.281	ENSETEG00000011979	AAR2	100	88.281	Echinops_telfairi
ENSG00000131043	AAR2	98	47.884	ENSEBUG00000014225	aar2	96	47.884	Eptatretus_burgeri
ENSG00000131043	AAR2	100	92.708	ENSEASG00005003415	AAR2	100	92.708	Equus_asinus_asinus
ENSG00000131043	AAR2	100	92.708	ENSECAG00000008929	AAR2	100	92.708	Equus_caballus
ENSG00000131043	AAR2	80	88.492	ENSEEUG00000004276	AAR2	80	88.492	Erinaceus_europaeus
ENSG00000131043	AAR2	99	61.619	ENSELUG00000001950	aar2	99	61.619	Esox_lucius
ENSG00000131043	AAR2	100	92.969	ENSFCAG00000033267	AAR2	100	92.969	Felis_catus
ENSG00000131043	AAR2	100	86.198	ENSFDAG00000007331	-	100	86.198	Fukomys_damarensis
ENSG00000131043	AAR2	100	92.969	ENSFDAG00000008861	-	100	92.969	Fukomys_damarensis
ENSG00000131043	AAR2	99	59.896	ENSFHEG00000022825	aar2	96	59.896	Fundulus_heteroclitus
ENSG00000131043	AAR2	98	61.640	ENSGMOG00000015584	aar2	99	61.640	Gadus_morhua
ENSG00000131043	AAR2	99	67.717	ENSGALG00000001034	AAR2	99	67.717	Gallus_gallus
ENSG00000131043	AAR2	99	59.948	ENSGAFG00000021110	aar2	98	59.948	Gambusia_affinis
ENSG00000131043	AAR2	98	61.905	ENSGACG00000002569	aar2	99	61.905	Gasterosteus_aculeatus
ENSG00000131043	AAR2	99	77.165	ENSGAGG00000008031	AAR2	99	77.165	Gopherus_agassizii
ENSG00000131043	AAR2	100	99.479	ENSGGOG00000027575	AAR2	100	99.479	Gorilla_gorilla
ENSG00000131043	AAR2	99	61.155	ENSHBUG00000004424	aar2	99	60.995	Haplochromis_burtoni
ENSG00000131043	AAR2	100	78.906	ENSHGLG00000009490	-	100	78.906	Heterocephalus_glaber_female
ENSG00000131043	AAR2	100	93.229	ENSHGLG00000015067	AAR2	100	93.229	Heterocephalus_glaber_female
ENSG00000131043	AAR2	100	93.229	ENSHGLG00100018810	AAR2	100	93.229	Heterocephalus_glaber_male
ENSG00000131043	AAR2	100	78.906	ENSHGLG00100011904	-	100	78.906	Heterocephalus_glaber_male
ENSG00000131043	AAR2	98	60.263	ENSHCOG00000011524	aar2	98	60.263	Hippocampus_comes
ENSG00000131043	AAR2	99	60.000	ENSIPUG00000017068	aar2	99	60.000	Ictalurus_punctatus
ENSG00000131043	AAR2	100	94.531	ENSSTOG00000011040	AAR2	87	94.531	Ictidomys_tridecemlineatus
ENSG00000131043	AAR2	99	80.940	ENSJJAG00000017217	-	98	80.940	Jaculus_jaculus
ENSG00000131043	AAR2	100	91.667	ENSJJAG00000010793	-	100	91.667	Jaculus_jaculus
ENSG00000131043	AAR2	99	61.097	ENSKMAG00000017869	aar2	99	61.097	Kryptolebias_marmoratus
ENSG00000131043	AAR2	98	62.698	ENSLBEG00000012649	aar2	99	62.698	Labrus_bergylta
ENSG00000131043	AAR2	99	67.363	ENSLACG00000011312	AAR2	99	67.363	Latimeria_chalumnae
ENSG00000131043	AAR2	99	63.185	ENSLOCG00000004809	aar2	99	63.185	Lepisosteus_oculatus
ENSG00000131043	AAR2	100	92.188	ENSLAFG00000006612	AAR2	100	92.188	Loxodonta_africana
ENSG00000131043	AAR2	100	97.917	ENSMFAG00000030564	AAR2	100	97.917	Macaca_fascicularis
ENSG00000131043	AAR2	100	97.917	ENSMMUG00000020691	AAR2	100	97.917	Macaca_mulatta
ENSG00000131043	AAR2	100	98.177	ENSMNEG00000037192	AAR2	100	98.177	Macaca_nemestrina
ENSG00000131043	AAR2	100	97.917	ENSMLEG00000037381	AAR2	100	97.917	Mandrillus_leucophaeus
ENSG00000131043	AAR2	99	60.209	ENSMAMG00000010708	aar2	98	60.209	Mastacembelus_armatus
ENSG00000131043	AAR2	63	73.684	ENSMZEG00005015310	-	97	73.684	Maylandia_zebra
ENSG00000131043	AAR2	99	61.155	ENSMZEG00005026542	aar2	98	61.155	Maylandia_zebra
ENSG00000131043	AAR2	100	93.490	ENSMAUG00000008346	Aar2	100	93.490	Mesocricetus_auratus
ENSG00000131043	AAR2	100	92.708	ENSMICG00000001707	AAR2	96	92.708	Microcebus_murinus
ENSG00000131043	AAR2	99	59.896	ENSMMOG00000020410	aar2	99	59.896	Mola_mola
ENSG00000131043	AAR2	98	71.316	ENSMODG00000001427	AAR2	99	71.316	Monodelphis_domestica
ENSG00000131043	AAR2	99	61.155	ENSMALG00000000239	aar2	98	61.155	Monopterus_albus
ENSG00000131043	AAR2	99	91.623	MGP_CAROLIEiJ_G0024559	Aar2	99	91.623	Mus_caroli
ENSG00000131043	AAR2	99	91.099	ENSMUSG00000027628	Aar2	100	90.476	Mus_musculus
ENSG00000131043	AAR2	99	90.838	MGP_PahariEiJ_G0026004	Aar2	100	90.476	Mus_pahari
ENSG00000131043	AAR2	99	91.361	MGP_SPRETEiJ_G0025481	Aar2	100	90.476	Mus_spretus
ENSG00000131043	AAR2	100	92.969	ENSMPUG00000017781	AAR2	100	92.969	Mustela_putorius_furo
ENSG00000131043	AAR2	100	90.885	ENSMLUG00000011977	AAR2	100	90.885	Myotis_lucifugus
ENSG00000131043	AAR2	99	61.417	ENSNBRG00000015002	aar2	99	61.257	Neolamprologus_brichardi
ENSG00000131043	AAR2	90	98.847	ENSNLEG00000032929	-	100	97.222	Nomascus_leucogenys
ENSG00000131043	AAR2	86	90.881	ENSOPRG00000012216	AAR2	100	90.881	Ochotona_princeps
ENSG00000131043	AAR2	86	92.121	ENSODEG00000013083	AAR2	100	92.857	Octodon_degus
ENSG00000131043	AAR2	99	61.417	ENSONIG00000017411	aar2	98	61.417	Oreochromis_niloticus
ENSG00000131043	AAR2	100	92.708	ENSOCUG00000005490	AAR2	100	92.708	Oryctolagus_cuniculus
ENSG00000131043	AAR2	99	62.467	ENSORLG00000009569	aar2	98	62.467	Oryzias_latipes
ENSG00000131043	AAR2	99	62.467	ENSORLG00020001463	aar2	98	62.467	Oryzias_latipes_hni
ENSG00000131043	AAR2	99	62.730	ENSORLG00015018773	aar2	98	62.730	Oryzias_latipes_hsok
ENSG00000131043	AAR2	99	62.205	ENSOMEG00000012193	aar2	98	62.205	Oryzias_melastigma
ENSG00000131043	AAR2	100	92.969	ENSOGAG00000001713	AAR2	100	92.969	Otolemur_garnettii
ENSG00000131043	AAR2	100	92.188	ENSOARG00000015597	AAR2	87	92.188	Ovis_aries
ENSG00000131043	AAR2	100	99.740	ENSPPAG00000038429	AAR2	100	99.740	Pan_paniscus
ENSG00000131043	AAR2	100	92.969	ENSPPRG00000011720	AAR2	100	92.969	Panthera_pardus
ENSG00000131043	AAR2	100	92.708	ENSPTIG00000020177	AAR2	100	92.708	Panthera_tigris_altaica
ENSG00000131043	AAR2	100	99.740	ENSPTRG00000013456	AAR2	100	99.740	Pan_troglodytes
ENSG00000131043	AAR2	95	97.534	ENSPANG00000017424	AAR2	93	97.534	Papio_anubis
ENSG00000131043	AAR2	99	60.836	ENSPKIG00000005382	aar2	99	60.836	Paramormyrops_kingsleyae
ENSG00000131043	AAR2	99	77.428	ENSPSIG00000016622	AAR2	99	77.428	Pelodiscus_sinensis
ENSG00000131043	AAR2	99	62.205	ENSPMGG00000008924	aar2	98	62.205	Periophthalmus_magnuspinnatus
ENSG00000131043	AAR2	100	92.969	ENSPEMG00000019521	Aar2	100	92.969	Peromyscus_maniculatus_bairdii
ENSG00000131043	AAR2	98	70.000	ENSPCIG00000014604	AAR2	99	70.000	Phascolarctos_cinereus
ENSG00000131043	AAR2	99	60.209	ENSPFOG00000006833	aar2	98	60.209	Poecilia_formosa
ENSG00000131043	AAR2	99	60.209	ENSPLAG00000005921	aar2	98	60.209	Poecilia_latipinna
ENSG00000131043	AAR2	86	58.610	ENSPMEG00000009910	aar2	92	58.610	Poecilia_mexicana
ENSG00000131043	AAR2	99	60.367	ENSPREG00000018031	aar2	98	60.367	Poecilia_reticulata
ENSG00000131043	AAR2	100	99.219	ENSPPYG00000010969	AAR2	100	99.219	Pongo_abelii
ENSG00000131043	AAR2	86	90.881	ENSPCAG00000016376	AAR2	100	90.881	Procavia_capensis
ENSG00000131043	AAR2	100	93.490	ENSPCOG00000014542	AAR2	100	93.490	Propithecus_coquereli
ENSG00000131043	AAR2	86	92.401	ENSPVAG00000005122	AAR2	100	92.401	Pteropus_vampyrus
ENSG00000131043	AAR2	99	60.892	ENSPNYG00000001908	aar2	99	60.733	Pundamilia_nyererei
ENSG00000131043	AAR2	99	62.078	ENSPNAG00000023281	aar2	99	62.078	Pygocentrus_nattereri
ENSG00000131043	AAR2	99	90.052	ENSRNOG00000020086	Aar2	99	90.052	Rattus_norvegicus
ENSG00000131043	AAR2	100	97.917	ENSRBIG00000035131	AAR2	100	97.917	Rhinopithecus_bieti
ENSG00000131043	AAR2	100	97.656	ENSRROG00000041883	AAR2	100	97.656	Rhinopithecus_roxellana
ENSG00000131043	AAR2	100	96.615	ENSSBOG00000034542	AAR2	100	96.615	Saimiri_boliviensis_boliviensis
ENSG00000131043	AAR2	77	67.873	ENSSFOG00015022013	aar2	99	67.873	Scleropages_formosus
ENSG00000131043	AAR2	99	60.733	ENSSMAG00000008182	aar2	98	60.733	Scophthalmus_maximus
ENSG00000131043	AAR2	99	62.042	ENSSDUG00000016232	aar2	99	61.880	Seriola_dumerili
ENSG00000131043	AAR2	99	62.042	ENSSLDG00000025293	aar2	98	62.042	Seriola_lalandi_dorsalis
ENSG00000131043	AAR2	100	88.802	ENSSARG00000010110	AAR2	100	88.802	Sorex_araneus
ENSG00000131043	AAR2	68	77.567	ENSSPUG00000008171	AAR2	99	77.567	Sphenodon_punctatus
ENSG00000131043	AAR2	98	62.368	ENSSPAG00000015946	-	98	62.368	Stegastes_partitus
ENSG00000131043	AAR2	99	62.304	ENSSPAG00000020332	aar2	98	62.368	Stegastes_partitus
ENSG00000131043	AAR2	100	92.448	ENSSSCG00000007315	AAR2	100	92.448	Sus_scrofa
ENSG00000131043	AAR2	66	71.260	ENSTGUG00000003427	AAR2	99	71.260	Taeniopygia_guttata
ENSG00000131043	AAR2	99	60.000	ENSTRUG00000002631	aar2	98	60.000	Takifugu_rubripes
ENSG00000131043	AAR2	99	59.690	ENSTNIG00000017872	aar2	99	59.690	Tetraodon_nigroviridis
ENSG00000131043	AAR2	100	92.448	ENSTBEG00000004101	AAR2	100	92.448	Tupaia_belangeri
ENSG00000131043	AAR2	86	92.705	ENSTTRG00000011494	AAR2	100	92.705	Tursiops_truncatus
ENSG00000131043	AAR2	100	92.188	ENSUAMG00000013466	AAR2	100	92.188	Ursus_americanus
ENSG00000131043	AAR2	100	92.188	ENSUMAG00000004174	AAR2	85	92.188	Ursus_maritimus
ENSG00000131043	AAR2	100	93.490	ENSVVUG00000000699	AAR2	100	93.490	Vulpes_vulpes
ENSG00000131043	AAR2	98	58.201	ENSXETG00000012109	aar2	98	58.201	Xenopus_tropicalis
ENSG00000131043	AAR2	99	59.948	ENSXCOG00000008078	aar2	99	59.948	Xiphophorus_couchianus
ENSG00000131043	AAR2	99	59.948	ENSXMAG00000015577	aar2	98	59.948	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000244	spliceosomal tri-snRNP complex assembly	21873635.	IBA	Process
GO:0005681	spliceosomal complex	-	IEA	Component