EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000131711 (Gene tree)
Gene ID: 4131
Gene Symbol: MAP1B
Alias: MAP5|PPP1R102
Full Name: microtubule associated protein 1B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 102,337 bases
Position: chr5:72,107,234-72,209,570
Accession: 6836
RBP type: non-canonical RBP
Summary: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22737234	Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].	PLoS One	2012	El Fatimy R	doi: 10.1371/journal.pone.0039338
21288476	Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.	Biochimie	2011 May	Fujiwara Y	doi: 10.1016/j.biochi.2011.01.008
16855020	QKI binds MAP1B mRNA and enhances MAP1B expression during oligodendrocyte development.	Mol Biol Cell	2006 Oct	Zhao L	-
21412434	TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization.	PLoS One	2011 Mar 11	Godena VK	doi: 10.1371/journal.pone.0017808.
20935173	Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria.	Hum Mol Genet	2011 Jan 1	Yao A	doi: 10.1093/hmg/ddq431
28466273	TDP-43 and Cytoskeletal Proteins in ALS.	Mol Neurobiol	2018 Apr	Oberstadt M	doi: 10.1007/s12035-017-0543-1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000512974	MAP1B-205	580	-	ENSP00000426312	122 (aa)	-	D6RGJ3
ENST00000511641	MAP1B-204	2056	-	ENSP00000423444	670 (aa)	-	D6RA32
ENST00000513526	MAP1B-206	2154	-	ENSP00000427194	103 (aa)	-	D6RCL2
ENST00000504183	MAP1B-202	572	-	-	- (aa)	-	-
ENST00000296755	MAP1B-201	12036	-	ENSP00000296755	2468 (aa)	-	P46821
ENST00000504492	MAP1B-203	2079	-	ENSP00000423416	569 (aa)	-	D6RA40

Gene Model

Click here to download ENSG00000131711's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000131711	Blood Pressure	6.5620000E-005	-
ENSG00000131711	Attention Deficit Disorder with Hyperactivity	2E-6	18839057

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000131711	rs2199161	5	72114529	?	Attention deficit hyperactivity disorder	18839057			EFO_0003888

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000131711's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000131711	MAP1B	100	98.361	ENSMUSG00000052727	Map1b	75	97.826	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000226	microtubule cytoskeleton organization	21873635.	IBA	Process
GO:0001578	microtubule bundle formation	-	IEA	Process
GO:0001750	photoreceptor outer segment	-	IEA	Component
GO:0001764	neuron migration	26609151.	TAS	Process
GO:0003779	actin binding	21873635.	IBA	Function
GO:0005198	structural molecule activity	1881920.	NAS	Function
GO:0005515	protein binding	12147674.15525354.18656471.24089205.25902260.	IPI	Function
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005874	microtubule	21873635.	IBA	Component
GO:0005874	microtubule	-	ISS	Component
GO:0005875	microtubule associated complex	21873635.	IBA	Component
GO:0005886	plasma membrane	19567321.	IDA	Component
GO:0007409	axonogenesis	21873635.	IBA	Process
GO:0008017	microtubule binding	21873635.	IBA	Function
GO:0008017	microtubule binding	-	ISS	Function
GO:0008017	microtubule binding	26609151.	TAS	Function
GO:0009987	cellular process	19567321.	IDA	Process
GO:0014069	postsynaptic density	-	IEA	Component
GO:0015631	tubulin binding	21873635.	IBA	Function
GO:0016358	dendrite development	21873635.	IBA	Process
GO:0030054	cell junction	-	IEA	Component
GO:0030424	axon	-	ISS	Component
GO:0030425	dendrite	21873635.	IBA	Component
GO:0030425	dendrite	-	ISS	Component
GO:0031114	regulation of microtubule depolymerization	21873635.	IBA	Process
GO:0032387	negative regulation of intracellular transport	-	IEA	Process
GO:0036477	somatodendritic compartment	-	ISS	Component
GO:0042995	cell projection	21873635.	IBA	Component
GO:0043025	neuronal cell body	21873635.	IBA	Component
GO:0043025	neuronal cell body	-	ISS	Component
GO:0043197	dendritic spine	-	IEA	Component
GO:0045202	synapse	21873635.	IBA	Component
GO:0045773	positive regulation of axon extension	-	IEA	Process
GO:0047497	mitochondrion transport along microtubule	-	IEA	Process
GO:0048675	axon extension	26609151.	TAS	Process
GO:0061162	establishment of monopolar cell polarity	-	IEA	Process
GO:0097440	apical dendrite	-	ISS	Component
GO:0097441	basal dendrite	-	ISS	Component
GO:0097457	hippocampal mossy fiber	-	ISS	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18656471	Microtubule-associated protein 1B light chain (MAP1B-LC1) negatively regulates the activity of tumor suppressor p53 in neuroblastoma cells.	FEBS Lett	2008 Aug 20	Lee SY	doi: 10.1016/j.febslet.2008.07.021

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	72197164	Frame_Shift_Del	NA	*L1272Wfs6**	0.34
ACC	chr5	72199354	Missense_Mutation	novel	T2000K	0.36
ACC	chr5	72199273	Missense_Mutation	novel	S1973N	0.09
BLCA	chr5	72197783	Missense_Mutation	NA	K1476N	0.24
BLCA	chr5	72197623	Missense_Mutation	novel	R1423T	0.49
BLCA	chr5	72194932	Missense_Mutation	novel	P526H	0.32
BLCA	chr5	72198430	Missense_Mutation	NA	S1692C	0.65
BLCA	chr5	72199589	Missense_Mutation	rs780987966	Q2078H	0.23
BLCA	chr5	72199590	Missense_Mutation	novel	D2079N	0.23
BLCA	chr5	72107699	Silent	novel	I56I	0.17
BLCA	chr5	72196735	Missense_Mutation	novel	S1127Y	0.37
BLCA	chr5	72186618	Missense_Mutation	rs747897650	R125H	0.47
BLCA	chr5	72195028	Missense_Mutation	rs756043501	R558H	0.49
BLCA	chr5	72196010	Silent	NA	T885T	0.22
BLCA	chr5	72196644	Missense_Mutation	rs774101263	E1097K	0.33
BLCA	chr5	72196662	Missense_Mutation	novel	E1103K	0.47
BLCA	chr5	72199344	Missense_Mutation	novel	G1997C	0.12
BLCA	chr5	72199857	Missense_Mutation	novel	E2168Q	0.1
BLCA	chr5	72194214	Missense_Mutation	NA	G287R	0.14
BLCA	chr5	72196740	Missense_Mutation	NA	E1129K	0.14
BLCA	chr5	72196771	Missense_Mutation	novel	P1139R	0.31
BLCA	chr5	72197835	Missense_Mutation	novel	E1494K	0.22
BLCA	chr5	72194973	Missense_Mutation	novel	D540N	0.37
BLCA	chr5	72195054	Missense_Mutation	NA	E567K	0.65
BLCA	chr5	72198972	Nonsense_Mutation	NA	Q1873*	0.83
BLCA	chr5	72199130	Silent	NA	T1925T	0.11
BLCA	chr5	72198870	Missense_Mutation	rs754067983	D1839N	0.93
BRCA	chr5	72199889	Missense_Mutation	NA	I2178M	0.24
BRCA	chr5	72197017	Missense_Mutation	rs6876207	S1221C	0.17
BRCA	chr5	72183763	Nonsense_Mutation	NA	R103*	0.18
BRCA	chr5	72197163	Frame_Shift_Ins	NA	*L1272Pfs3**	0.35
BRCA	chr5	72196427	Silent	NA	D1024D	0.18
BRCA	chr5	72199801	Nonsense_Mutation	novel	S2149*	0.08
BRCA	chr5	72203711	Silent	NA	V2387V	0.12
BRCA	chr5	72197091	Frame_Shift_Del	novel	*V1246Ffs14**	0.1
BRCA	chr5	72205483	3'UTR	novel		0.17
BRCA	chr5	72115767	Missense_Mutation	NA	R85Q	0.11
BRCA	chr5	72194207	Silent	NA	I284I	0.15
BRCA	chr5	72195575	Missense_Mutation	NA	K740N	0.27
BRCA	chr5	72194858	Frame_Shift_Ins	novel	*L502Efs42**	0.27
BRCA	chr5	72205471	3'UTR	novel		0.75
CESC	chr5	72198261	Nonsense_Mutation	NA	Q1636*	0.19
CESC	chr5	72197537	Silent	NA	V1394V	0.21
CESC	chr5	72199391	Missense_Mutation	NA	E2012D	0.43
CESC	chr5	72198618	Missense_Mutation	novel	P1755T	0.42
CESC	chr5	72205608	3'UTR	novel		0.5
CESC	chr5	72115750	Silent	NA	L79L	0.45
CESC	chr5	72198553	Missense_Mutation	novel	S1733C	0.45
CESC	chr5	72194343	Missense_Mutation	novel	E330Q	0.12
CESC	chr5	72195311	Silent	novel	E652E	0.18
CESC	chr5	72195234	Missense_Mutation	novel	D627Y	0.37
CESC	chr5	72194764	Missense_Mutation	novel	S470L	0.29
CESC	chr5	72205511	3'UTR	novel		0.41
CESC	chr5	72199993	Missense_Mutation	rs754794035	R2213H	0.41
CESC	chr5	72194784	Missense_Mutation	NA	P477T	0.23
CESC	chr5	72195072	Missense_Mutation	NA	H573D	0.18
CESC	chr5	72195815	Silent	NA	A820A	0.28
CESC	chr5	72195831	Missense_Mutation	NA	E826Q	0.35
CESC	chr5	72197290	Missense_Mutation	novel	S1312I	0.18
CESC	chr5	72197179	Missense_Mutation	rs372421201	R1275H	0.35
CESC	chr5	72198853	Missense_Mutation	rs199724316	R1833H	0.22
CESC	chr5	72200279	Silent	novel	V2308V	0.5
CESC	chr5	72205485	3'UTR	novel		0.39
CHOL	chr5	72196110	Nonsense_Mutation	novel	G919*	0.28
COAD	chr5	72198729	Missense_Mutation	NA	S1792P	0.44
COAD	chr5	72199257	Missense_Mutation	NA	E1968K	0.09
COAD	chr5	72194109	Missense_Mutation	novel	G252C	0.35
COAD	chr5	72199967	Silent	rs574061088	P2204P	0.28
COAD	chr5	72197141	Silent	novel	S1262S	0.08
COAD	chr5	72186689	Nonsense_Mutation	NA	E149*	0.52
COAD	chr5	72194901	Missense_Mutation	NA	A516T	0.45
COAD	chr5	72195894	Nonsense_Mutation	NA	E847*	0.36
COAD	chr5	72198060	Missense_Mutation	NA	D1569N	0.38
COAD	chr5	72199453	Missense_Mutation	rs756620120	R2033Q	0.4
COAD	chr5	72195330	Nonsense_Mutation	NA	E659*	0.59
COAD	chr5	72195660	Missense_Mutation	novel	D769N	0.08
COAD	chr5	72199493	Missense_Mutation	novel	E2046D	0.27
COAD	chr5	72198718	Frame_Shift_Del	novel	*P1789Hfs34**	0.31
COAD	chr5	72196573	Missense_Mutation	novel	G1073E	0.14
COAD	chr5	72200070	Missense_Mutation	novel	L2239M	0.35
COAD	chr5	72186617	Missense_Mutation	rs778270951	R125C	0.1
COAD	chr5	72195601	Frame_Shift_Ins	NA	*P752Tfs35**	0.35
COAD	chr5	72196101	Missense_Mutation	NA	E916K	0.11
COAD	chr5	72198264	Missense_Mutation	NA	D1637Y	0.3
COAD	chr5	72198731	Silent	NA	S1792S	0.24
COAD	chr5	72199565	Missense_Mutation	NA	K2070N	0.39
COAD	chr5	72196471	Missense_Mutation	novel	M1039K	0.16
COAD	chr5	72197559	Missense_Mutation	NA	P1402S	0.63
COAD	chr5	72196868	Silent	novel	S1171S	0.08
COAD	chr5	72195023	Silent	rs767457558	S556S	0.16
COAD	chr5	72196839	Missense_Mutation	NA	I1162V	0.35
COAD	chr5	72197420	Missense_Mutation	novel	K1355N	0.47
COAD	chr5	72183764	Missense_Mutation	NA	R103Q	0.15
COAD	chr5	72196811	Silent	rs145061898	T1152T	0.04
COAD	chr5	72186617	Missense_Mutation	rs778270951	R125C	0.38
COAD	chr5	72197558	Silent	NA	P1401P	0.4
COAD	chr5	72199841	Frame_Shift_Ins	novel	*E2165Gfs3**	0.32
COAD	chr5	72186656	Missense_Mutation	rs147013566	V138M	0.19
COAD	chr5	72196148	Silent	rs151211314	A931A	0.2
COAD	chr5	72195965	Frame_Shift_Del	novel	*E871Afs22**	0.13
COAD	chr5	72195601	Frame_Shift_Ins	NA	*P752Tfs35**	0.39
COAD	chr5	72196964	Silent	NA	S1203S	0.44
COAD	chr5	72183742	Splice_Site	NA	X96_splice	0.29
COAD	chr5	72199532	Silent	rs567310466	Y2059Y	0.18
COAD	chr5	72197140	Missense_Mutation	NA	S1262Y	0.14
COAD	chr5	72196355	Silent	rs148153706	A1000A	0.58
COAD	chr5	72199045	Missense_Mutation	rs781044243	R1897Q	0.24
COAD	chr5	72197980	Missense_Mutation	rs753038766	T1542M	0.24
COAD	chr5	72197016	Missense_Mutation	novel	S1221A	0.15
COAD	chr5	72195975	Missense_Mutation	rs780650498	E874K	0.37
COAD	chr5	72195664	Missense_Mutation	NA	S770Y	0.11
COAD	chr5	72199845	Missense_Mutation	NA	P2164T	0.15
COAD	chr5	72115767	Missense_Mutation	NA	R85Q	0.33
COAD	chr5	72197162	Missense_Mutation	rs778832697	K1269N	0.38
COAD	chr5	72198032	Silent	NA	T1559T	0.29
COAD	chr5	72198623	Silent	NA	P1756P	0.38
COAD	chr5	72194430	Missense_Mutation	NA	L359I	0.37
COAD	chr5	72196672	Missense_Mutation	NA	R1106Q	0.26
COAD	chr5	72196206	Missense_Mutation	NA	A951T	0.18
COAD	chr5	72196832	Silent	rs183960902	F1159F	0.21
COAD	chr5	72199127	Silent	NA	E1924E	0.14
COAD	chr5	72200231	Missense_Mutation	NA	K2292N	0.18
COAD	chr5	72199421	Frame_Shift_Ins	novel	*Y2023Afs214**	0.03
COAD	chr5	72198916	Missense_Mutation	novel	P1854H	0.07
COAD	chr5	72199198	Missense_Mutation	rs139240427	R1948Q	0.32
DLBC	chr5	72196536	Missense_Mutation	novel	Q1061K	0.4
DLBC	chr5	72199937	Silent	rs368060624	T2194T	0.4
DLBC	chr5	72200053	Missense_Mutation	novel	K2233T	0.1
ESCA	chr5	72199747	Missense_Mutation	rs747707013	P2131L	0.3
ESCA	chr5	72199808	Silent	rs543732551	S2151S	0.5
ESCA	chr5	72186706	Silent	novel	S154S	0.11
ESCA	chr5	72186730	Missense_Mutation	novel	F162L	0.33
ESCA	chr5	72107573	Silent	novel	S14S	0.23
ESCA	chr5	72197624	Missense_Mutation	novel	R1423S	0.28
ESCA	chr5	72198345	Nonsense_Mutation	novel	R1664*	0.18
ESCA	chr5	72198216	Missense_Mutation	novel	P1621S	0.14
ESCA	chr5	72199215	Missense_Mutation	rs776597827	G1954R	0.32
GBM	chr5	72194695	Missense_Mutation	novel	D447A	0.11
GBM	chr5	72197574	Missense_Mutation	rs200451397	E1407K	0.11
GBM	chr5	72200357	Silent	rs759772358	T2334T	0.06
GBM	chr5	72198597	Missense_Mutation	NA	D1748Y	0.38
GBM	chr5	72199815	Missense_Mutation	novel	A2154S	0.16
GBM	chr5	72197209	Frame_Shift_Del	novel	*E1285Gfs10**	0.34
GBM	chr5	72194352	Nonsense_Mutation	novel	E333*	0.09
GBM	chr5	72195544	Missense_Mutation	novel	K730T	0.06
GBM	chr5	72198069	Missense_Mutation	novel	P1572T	0.04
GBM	chr5	72199332	Missense_Mutation	novel	D1993H	0.05
GBM	chr5	72194828	Silent	novel	G491G	0.18
GBM	chr5	72196846	Missense_Mutation	rs777166306	K1164T	0.23
GBM	chr5	72197631	Missense_Mutation	rs535672589	E1426K	0.36
GBM	chr5	72199386	Missense_Mutation	rs759455891	T2011A	0.21
GBM	chr5	72203777	Missense_Mutation	novel	K2409N	0.2
GBM	chr5	72203630	Silent	novel	L2360L	0.09
GBM	chr5	72197546	Silent	novel	P1397P	0.04
GBM	chr5	72194157	Frame_Shift_Ins	novel	*G268Vfs11**	0.03
GBM	chr5	72194202	Frame_Shift_Del	novel	*L283Sfs19**	0.06
GBM	chr5	72199563	Missense_Mutation	novel	K2070Q	0.09
GBM	chr5	72183812	Missense_Mutation	novel	A119G	0.05
GBM	chr5	72196304	Missense_Mutation	novel	D983E	0.07
GBM	chr5	72198242	Silent	NA	A1629A	0.26
GBM	chr5	72195005	Silent	NA	K550K	0.33
GBM	chr5	72197489	Frame_Shift_Del	novel	*M1380Wfs35**	0.05
HNSC	chr5	72186745	Silent	rs111766097	T167T	0.73
HNSC	chr5	72198142	Missense_Mutation	novel	Q1596R	0.15
HNSC	chr5	72198870	Missense_Mutation	rs754067983	D1839N	0.43
HNSC	chr5	72199521	Missense_Mutation	novel	T2056A	0.15
HNSC	chr5	72198199	Missense_Mutation	novel	R1615T	0.08
HNSC	chr5	72205389	3'UTR	novel		0.5
HNSC	chr5	72186619	Silent	novel	R125R	0.15
HNSC	chr5	72199529	Silent	NA	S2058S	0.13
HNSC	chr5	72197108	Silent	novel	V1251V	0.2
HNSC	chr5	72198757	Missense_Mutation	rs368052791	S1801L	0.16
HNSC	chr5	72197169	Missense_Mutation	novel	L1272M	0.66
HNSC	chr5	72195709	Missense_Mutation	novel	I785N	0.34
HNSC	chr5	72205181	Missense_Mutation	novel	S2450N	0.05
HNSC	chr5	72195302	Missense_Mutation	novel	K649N	0.28
HNSC	chr5	72195735	Missense_Mutation	novel	A794S	0.1
HNSC	chr5	72186700	Silent	novel	L152L	0.04
HNSC	chr5	72195096	Missense_Mutation	novel	E581Q	0.16
HNSC	chr5	72198240	Missense_Mutation	novel	A1629S	0.07
HNSC	chr5	72196425	Missense_Mutation	novel	D1024N	0.76
HNSC	chr5	72196462	Missense_Mutation	rs145156470	P1036L	0.3
HNSC	chr5	72195672	Missense_Mutation	novel	A773T	0.22
HNSC	chr5	72195580	Missense_Mutation	rs570357353	S742L	0.1
HNSC	chr5	72197117	Silent	rs775909918	S1254S	0.13
HNSC	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.5
HNSC	chr5	72198545	Silent	rs758570511	P1730P	0.4
KICH	chr5	72198009	Missense_Mutation	novel	V1552M	0.59
KIRC	chr5	72199568	Silent	NA	K2071K	0.32
KIRC	chr5	72199064	Silent	NA	G1903G	0.32
KIRP	chr5	72107605	Missense_Mutation	novel	S25L	0.45
KIRP	chr5	72183821	Missense_Mutation	NA	T122N	0.33
KIRP	chr5	72194746	Missense_Mutation	novel	S464C	0.29
KIRP	chr5	72199801	Nonsense_Mutation	NA	S2149*	0.13
LAML	chr5	72193870	Missense_Mutation	novel	G172A	0.04
LAML	chr5	72205670	3'UTR	novel		0.2
LGG	chr5	72199246	Missense_Mutation	novel	T1964S	0.07
LGG	chr5	72197784	Missense_Mutation	NA	K1477E	0.32
LGG	chr5	72186655	Silent	rs373867264	L137L	0.38
LGG	chr5	72194796	Missense_Mutation	novel	A481T	0.09
LGG	chr5	72195899	Silent	rs746451505	V848V	0.4
LGG	chr5	72197126	Silent	rs757277389	P1257P	0.36
LGG	chr5	72198461	Missense_Mutation	novel	K1702N	0.29
LGG	chr5	72199419	Missense_Mutation	novel	G2022C	0.06
LGG	chr5	72200358	Missense_Mutation	rs370354996	A2335T	0.1
LGG	chr5	72198451	Frame_Shift_Ins	novel	*L1699Ffs7**	0.08
LGG	chr5	72197461	Missense_Mutation	novel	K1369R	0.47
LIHC	chr5	72195648	Missense_Mutation	NA	S765P	0.15
LIHC	chr5	72197494	Missense_Mutation	NA	M1380K	0.37
LIHC	chr5	72195737	Silent	NA	A794A	0.61
LIHC	chr5	72198306	Missense_Mutation	NA	Q1651K	0.24
LIHC	chr5	72194070	Missense_Mutation	rs775351695	V239I	0.16
LIHC	chr5	72198627	Missense_Mutation	NA	D1758H	0.36
LIHC	chr5	72197363	Silent	rs771081682	Y1336Y	0.34
LIHC	chr5	72107634	Missense_Mutation	novel	S35R	0.2
LIHC	chr5	72205091	Missense_Mutation	novel	L2420Q	0.5
LIHC	chr5	72115772	Missense_Mutation	novel	S87T	0.2
LIHC	chr5	72195997	Missense_Mutation	novel	E881V	0.23
LIHC	chr5	72200305	Missense_Mutation	novel	D2317V	0.38
LIHC	chr5	72199022	Silent	novel	Y1889Y	0.59
LIHC	chr5	72196506	Nonsense_Mutation	novel	K1051*	0.13
LIHC	chr5	72199296	Nonsense_Mutation	novel	R1981*	0.22
LUAD	chr5	72196266	Missense_Mutation	novel	P971T	0.2
LUAD	chr5	72199983	Missense_Mutation	novel	P2210T	0.3
LUAD	chr5	72198380	Silent	rs768923611	G1675G	0.45
LUAD	chr5	72199384	Missense_Mutation	NA	T2010N	0.4
LUAD	chr5	72195726	Missense_Mutation	NA	A791S	0.08
LUAD	chr5	72195061	Missense_Mutation	rs754686684	T569K	0.17
LUAD	chr5	72198141	In_Frame_Del	novel	Q1596_P1598del	0.08
LUAD	chr5	72195755	Silent	NA	G800G	0.45
LUAD	chr5	72195725	Missense_Mutation	NA	K790N	0.65
LUAD	chr5	72197453	Silent	NA	S1366S	0.3
LUAD	chr5	72196247	Silent	NA	V964V	0.21
LUAD	chr5	72199257	Nonsense_Mutation	novel	E1968*	0.12
LUAD	chr5	72199704	Nonsense_Mutation	novel	E2117*	0.37
LUAD	chr5	72197957	In_Frame_Ins	novel	V1534_D1535insCLGK	0.07
LUAD	chr5	72199596	Missense_Mutation	novel	D2081Y	0.43
LUAD	chr5	72197344	Missense_Mutation	novel	S1330N	0.37
LUAD	chr5	72197817	Missense_Mutation	novel	P1488S	0.24
LUAD	chr5	72197943	Missense_Mutation	novel	S1530T	0.06
LUAD	chr5	72199846	Missense_Mutation	NA	P2164Q	0.28
LUAD	chr5	72196301	Silent	novel	A982A	0.29
LUAD	chr5	72199501	Missense_Mutation	novel	T2049S	0.26
LUAD	chr5	72199982	Missense_Mutation	novel	S2209R	0.13
LUAD	chr5	72197966	Silent	NA	G1537G	0.49
LUAD	chr5	72198565	Frame_Shift_Del	novel	*P1738Lfs85**	0.1
LUAD	chr5	72200334	Missense_Mutation	NA	S2327T	0.07
LUAD	chr5	72198207	Missense_Mutation	NA	S1618P	0.15
LUAD	chr5	72194204	Silent	NA	L283L	0.65
LUAD	chr5	72195014	Silent	novel	P553P	0.36
LUAD	chr5	72200069	Missense_Mutation	novel	D2238E	0.81
LUAD	chr5	72205253	3'UTR	novel		0.55
LUAD	chr5	72198133	Missense_Mutation	NA	S1593F	0.17
LUAD	chr5	72196315	Missense_Mutation	novel	R987K	0.16
LUAD	chr5	72183795	Silent	novel	I113I	0.56
LUAD	chr5	72194375	Silent	NA	T340T	0.33
LUAD	chr5	72199829	Silent	NA	T2158T	0.38
LUAD	chr5	72115796	Missense_Mutation	NA	P95T	0.25
LUAD	chr5	72196395	Missense_Mutation	novel	E1014K	0.2
LUAD	chr5	72197499	Missense_Mutation	novel	E1382K	0.35
LUAD	chr5	72195753	Missense_Mutation	novel	G800C	0.17
LUAD	chr5	72194230	Missense_Mutation	novel	S292F	0.37
LUAD	chr5	72196414	Missense_Mutation	novel	A1020D	0.31
LUAD	chr5	72198539	Silent	NA	A1728A	0.54
LUAD	chr5	72196709	Silent	novel	G1118G	0.19
LUSC	chr5	72198678	Missense_Mutation	novel	G1775R	0.22
LUSC	chr5	72197121	Missense_Mutation	novel	S1256C	0.44
LUSC	chr5	72197303	Silent	NA	K1316K	0.21
LUSC	chr5	72197720	Missense_Mutation	rs745772849	Q1455H	0.39
LUSC	chr5	72195243	Missense_Mutation	novel	P630S	0.48
LUSC	chr5	72183825	Missense_Mutation	novel	E123D	0.05
LUSC	chr5	72196476	Missense_Mutation	novel	A1041T	0.08
LUSC	chr5	72199856	Silent	novel	E2167E	0.24
LUSC	chr5	72195781	Missense_Mutation	NA	M809K	0.41
LUSC	chr5	72199155	Missense_Mutation	novel	E1934K	0.12
LUSC	chr5	72199255	Missense_Mutation	novel	P1967L	0.6
LUSC	chr5	72198876	Missense_Mutation	NA	M1841L	0.16
LUSC	chr5	72198003	Missense_Mutation	NA	A1550S	0.54
LUSC	chr5	72195974	Silent	NA	V873V	0.74
LUSC	chr5	72194246	Silent	NA	L297L	0.51
LUSC	chr5	72199464	Missense_Mutation	novel	T2037A	0.64
LUSC	chr5	72194467	Missense_Mutation	rs749045605	N371S	0.19
LUSC	chr5	72196502	Silent	rs200412679	V1049V	0.25
OV	chr5	72194213	Silent	rs777817448	G286G	0.41
OV	chr5	72195088	Missense_Mutation	novel	P578H	0.1
OV	chr5	72197371	Missense_Mutation	novel	S1339C	0.03
OV	chr5	72198443	Missense_Mutation	novel	D1696E	0.13
OV	chr5	72196757	Missense_Mutation	novel	D1134E	0.06
OV	chr5	72198190	Frame_Shift_Ins	novel	*C1613Mfs15**	0.05
OV	chr5	72198857	Silent	novel	A1834A	0.06
OV	chr5	72195107	Silent	NA	E584E	0.4
OV	chr5	72195468	Missense_Mutation	novel	P705S	0.82
OV	chr5	72195088	Missense_Mutation	novel	P578H	0.17
OV	chr5	72195687	Missense_Mutation	novel	E778K	0.04
OV	chr5	72197267	Missense_Mutation	NA	E1304D	0.38
OV	chr5	72195113	Silent	novel	V586V	0.04
OV	chr5	72195498	Nonsense_Mutation	novel	K715*	0.13
PAAD	chr5	72199044	Missense_Mutation	rs757286026	R1897W	0.6
PAAD	chr5	72199257	Missense_Mutation	NA	E1968K	0.18
PAAD	chr5	72194345	Silent	novel	E330E	0.2
PAAD	chr5	72194714	Silent	novel	L453L	0.16
PAAD	chr5	72196023	Missense_Mutation	rs139604402	E890K	0.19
PAAD	chr5	72197080	Missense_Mutation	novel	S1242N	0.15
PAAD	chr5	72199249	Missense_Mutation	novel	S1965I	0.18
PAAD	chr5	72199514	Missense_Mutation	novel	Q2053H	0.17
PAAD	chr5	72199993	Missense_Mutation	rs754794035	R2213H	0.18
PAAD	chr5	72194262	Nonsense_Mutation	novel	R303*	0.48
PRAD	chr5	72196808	Silent	novel	E1151E	0.09
PRAD	chr5	72203793	Frame_Shift_Ins	novel	*N2415Tfs5**	0.31
PRAD	chr5	72203794	Frame_Shift_Ins	novel	*M2416Afs4**	0.31
PRAD	chr5	72197179	Missense_Mutation	rs372421201	R1275H	0.11
PRAD	chr5	72196908	Missense_Mutation	rs371761339	G1185R	0.56
PRAD	chr5	72199748	Silent	rs149330290	P2131P	0.37
READ	chr5	72195069	Missense_Mutation	rs772620413	N572D	0.3
READ	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.25
READ	chr5	72199936	Missense_Mutation	rs746663170	T2194M	0.27
READ	chr5	72194325	Missense_Mutation	novel	L324I	0.11
READ	chr5	72199571	Silent	novel	S2072S	0.05
READ	chr5	72186664	Silent	rs765418185	T140T	0.41
READ	chr5	72200195	Silent	NA	S2280S	0.28
READ	chr5	72194474	Silent	NA	K373K	0.24
READ	chr5	72194041	Missense_Mutation	novel	F229C	0.07
READ	chr5	72194736	Missense_Mutation	NA	L461I	0.25
READ	chr5	72195575	Missense_Mutation	NA	K740N	0.07
READ	chr5	72196915	Missense_Mutation	NA	S1187Y	0.15
READ	chr5	72197463	Missense_Mutation	NA	D1370Y	0.12
READ	chr5	72198476	Missense_Mutation	NA	E1707D	0.22
READ	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.45
READ	chr5	72196619	Missense_Mutation	novel	E1088D	0.42
READ	chr5	72199198	Missense_Mutation	rs139240427	R1948Q	0.39
READ	chr5	72199493	Missense_Mutation	novel	E2046D	0.4
READ	chr5	72194317	Missense_Mutation	novel	N321S	0.13
READ	chr5	72195541	Missense_Mutation	NA	K729T	0.13
READ	chr5	72196430	Missense_Mutation	novel	K1025N	0.46
READ	chr5	72197595	Missense_Mutation	NA	L1414I	0.52
READ	chr5	72197898	Nonsense_Mutation	NA	E1515*	0.11
READ	chr5	72198579	Missense_Mutation	rs568428215	A1742T	0.32
READ	chr5	72199076	Missense_Mutation	NA	E1907D	0.43
SARC	chr5	72193967	Missense_Mutation	novel	H204Q	0.42
SARC	chr5	72205570	3'UTR	rs753263023		0.25
SARC	chr5	72197221	Missense_Mutation	novel	S1289F	0.26
SKCM	chr5	72199032	Missense_Mutation	NA	E1893K	0.23
SKCM	chr5	72195039	In_Frame_Ins	novel	E564dup	0.16
SKCM	chr5	72197425	Missense_Mutation	rs202226597	P1357L	0.42
SKCM	chr5	72186706	Silent	rs755865663	S154S	0.27
SKCM	chr5	72183764	Missense_Mutation	NA	R103Q	0.25
SKCM	chr5	72186628	Silent	NA	I128I	0.25
SKCM	chr5	72194582	Silent	NA	V409V	0.18
SKCM	chr5	72195560	Silent	NA	L735L	0.37
SKCM	chr5	72199482	Missense_Mutation	NA	E2043K	0.22
SKCM	chr5	72199720	Missense_Mutation	NA	P2122L	0.28
SKCM	chr5	72200315	Silent	NA	T2320T	0.29
SKCM	chr5	72194249	Silent	NA	I298I	0.66
SKCM	chr5	72197136	Missense_Mutation	NA	P1261S	0.49
SKCM	chr5	72198694	Missense_Mutation	NA	P1780L	0.39
SKCM	chr5	72200244	Missense_Mutation	NA	E2297K	0.5
SKCM	chr5	72205380	3'UTR	novel		0.4
SKCM	chr5	72194807	Silent	novel	I484I	0.43
SKCM	chr5	72115783	Missense_Mutation	NA	F90L	0.28
SKCM	chr5	72198227	Silent	NA	F1624F	0.24
SKCM	chr5	72197283	Missense_Mutation	novel	C1310R	0.28
SKCM	chr5	72196630	Missense_Mutation	novel	G1092E	0.52
SKCM	chr5	72199889	Silent	rs147666683	I2178I	0.64
SKCM	chr5	72196832	Silent	rs183960902	F1159F	0.56
SKCM	chr5	72197953	Missense_Mutation	NA	P1533L	0.28
SKCM	chr5	72199243	Missense_Mutation	novel	T1963I	0.51
SKCM	chr5	72199244	Silent	rs769967633	T1963T	0.52
SKCM	chr5	72186717	Missense_Mutation	NA	S158F	0.19
SKCM	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.47
SKCM	chr5	72197060	Silent	novel	T1235T	0.15
SKCM	chr5	72193917	Silent	NA	L188L	0.41
SKCM	chr5	72196234	Missense_Mutation	NA	E960G	0.4
SKCM	chr5	72199607	Silent	NA	L2084L	0.86
SKCM	chr5	72198607	Missense_Mutation	NA	S1751F	0.31
SKCM	chr5	72197631	Missense_Mutation	rs535672589	E1426K	0.11
SKCM	chr5	72198634	Missense_Mutation	novel	S1760F	0.23
SKCM	chr5	72199890	Missense_Mutation	novel	D2179N	0.24
SKCM	chr5	72200310	Missense_Mutation	NA	E2319K	0.42
SKCM	chr5	72199846	Missense_Mutation	NA	P2164L	0.18
SKCM	chr5	72115783	Silent	NA	F90F	0.09
SKCM	chr5	72198711	Missense_Mutation	NA	P1786S	0.15
SKCM	chr5	72194589	In_Frame_Del	novel	F412del	0.32
SKCM	chr5	72198609	Missense_Mutation	rs569299339	D1752N	0.49
SKCM	chr5	72197560	Missense_Mutation	NA	P1402L	0.1
SKCM	chr5	72197952	Missense_Mutation	novel	P1533S	0.31
SKCM	chr5	72205082	Splice_Site	novel	X2418_splice	0.56
SKCM	chr5	72196832	Silent	rs183960902	F1159F	0.45
SKCM	chr5	72200016	Missense_Mutation	novel	D2221N	0.35
SKCM	chr5	72115702	Silent	novel	I63I	0.35
SKCM	chr5	72194867	Silent	novel	K504K	0.23
SKCM	chr5	72196119	Missense_Mutation	rs773432814	D922N	0.19
SKCM	chr5	72198974	Silent	novel	Q1873Q	0.52
SKCM	chr5	72199671	Missense_Mutation	novel	P2106S	0.62
STAD	chr5	72196857	Missense_Mutation	NA	S1168T	0.62
STAD	chr5	72199993	Missense_Mutation	rs754794035	R2213H	0.17
STAD	chr5	72195131	Silent	NA	K592K	0.3
STAD	chr5	72196810	Missense_Mutation	rs749214681	T1152M	0.21
STAD	chr5	72196803	Missense_Mutation	novel	E1150K	0.26
STAD	chr5	72196901	Silent	rs148313643	P1182P	0.17
STAD	chr5	72195396	Frame_Shift_Del	novel	*E683Kfs39**	0.36
STAD	chr5	72199992	Missense_Mutation	rs573728562	R2213C	0.32
STAD	chr5	72194213	Silent	rs777817448	G286G	0.08
STAD	chr5	72115767	Missense_Mutation	NA	R85L	0.3
STAD	chr5	72199901	Silent	rs77733766	D2182D	0.37
STAD	chr5	72196465	Frame_Shift_Del	NA	*M1039Wfs7**	0.18
STAD	chr5	72195266	Silent	rs140902387	T637T	0.24
STAD	chr5	72200245	Frame_Shift_Del	novel	*K2298Rfs90**	0.39
STAD	chr5	72200161	Missense_Mutation	NA	A2269E	0.28
STAD	chr5	72195783	Missense_Mutation	NA	A810T	0.5
STAD	chr5	72197163	Frame_Shift_Ins	NA	*L1272Pfs3**	0.17
STAD	chr5	72197179	Missense_Mutation	rs372421201	R1275H	0.42
STAD	chr5	72198869	Silent	rs766462360	F1838F	0.3
STAD	chr5	72195715	Missense_Mutation	novel	K787T	0.44
STAD	chr5	72197745	Missense_Mutation	novel	D1464Y	0.16
STAD	chr5	72198741	Missense_Mutation	rs775654536	Y1796H	0.45
STAD	chr5	72200090	Frame_Shift_Ins	novel	*P2248Afs15**	0.33
STAD	chr5	72199269	Missense_Mutation	NA	Y1972H	0.08
STAD	chr5	72194833	Missense_Mutation	rs140205740	S493N	0.12
STAD	chr5	72196250	Silent	rs193173542	S965S	0.12
STAD	chr5	72198327	Missense_Mutation	novel	L1658I	0.22
STAD	chr5	72196118	Silent	rs183520146	D921D	0.25
STAD	chr5	72197126	Silent	rs757277389	P1257P	0.15
STAD	chr5	72199197	Missense_Mutation	rs151255965	R1948W	0.13
STAD	chr5	72203746	Missense_Mutation	rs144647263	R2399Q	0.3
STAD	chr5	72198418	Missense_Mutation	NA	D1688A	0.11
STAD	chr5	72197421	Missense_Mutation	novel	P1356S	0.2
STAD	chr5	72205345	3'UTR	novel		0.67
STAD	chr5	72198320	Silent	NA	E1655E	0.3
STAD	chr5	72199965	Missense_Mutation	NA	P2204S	0.22
STAD	chr5	72195602	Frame_Shift_Del	NA	*K751Nfs5**	0.23
STAD	chr5	72197920	Missense_Mutation	novel	S1522F	0.06
STAD	chr5	72199532	Silent	rs567310466	Y2059Y	0.21
STAD	chr5	72195954	Silent	NA	L867L	0.33
STAD	chr5	72195601	Frame_Shift_Ins	NA	*P752Tfs35**	0.47
STAD	chr5	72196980	Missense_Mutation	novel	P1209S	0.42
STAD	chr5	72194126	Silent	NA	L257L	0.26
STAD	chr5	72199380	Nonsense_Mutation	NA	E2009*	0.22
STAD	chr5	72194798	Silent	rs533759374	A481A	0.15
STAD	chr5	72195911	Missense_Mutation	NA	K852N	0.1
STAD	chr5	72199955	Silent	novel	P2200P	0.37
TGCT	chr5	72193897	Missense_Mutation	novel	A181G	0.24
THCA	chr5	72199336	Missense_Mutation	NA	S1994F	0.04
THCA	chr5	72197165	Silent	NA	T1270T	0.33
THCA	chr5	72194201	Missense_Mutation	NA	M282I	0.09
UCEC	chr5	72195153	Missense_Mutation	NA	P600T	0.39
UCEC	chr5	72206473	3'UTR	novel		0.38
UCEC	chr5	72194485	Missense_Mutation	NA	S377I	0.31
UCEC	chr5	72195315	Nonsense_Mutation	NA	E654*	0.35
UCEC	chr5	72195819	Nonsense_Mutation	NA	E822*	0.64
UCEC	chr5	72196593	Nonsense_Mutation	NA	E1080*	0.26
UCEC	chr5	72197076	Missense_Mutation	rs752661585	D1241Y	0.33
UCEC	chr5	72197219	Silent	NA	V1288V	0.2
UCEC	chr5	72197871	Missense_Mutation	NA	D1506Y	0.27
UCEC	chr5	72196893	Missense_Mutation	novel	V1180I	0.65
UCEC	chr5	72194524	Missense_Mutation	NA	K390T	0.26
UCEC	chr5	72195260	Silent	rs770695366	E635E	0.3
UCEC	chr5	72195900	Missense_Mutation	rs770602834	D849N	0.31
UCEC	chr5	72199906	Missense_Mutation	NA	S2184L	0.24
UCEC	chr5	72186745	Silent	rs111766097	T167T	0.41
UCEC	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.33
UCEC	chr5	72198461	Missense_Mutation	novel	K1702N	0.33
UCEC	chr5	72199535	Silent	novel	E2060E	0.19
UCEC	chr5	72205282	3'UTR	novel		0.47
UCEC	chr5	72196747	Frame_Shift_Del	novel	*M1133Wfs10**	0.26
UCEC	chr5	72115745	Nonsense_Mutation	NA	E78*	0.25
UCEC	chr5	72195595	Missense_Mutation	NA	S747Y	0.33
UCEC	chr5	72195939	Missense_Mutation	rs761941048	E862K	0.29
UCEC	chr5	72196309	Missense_Mutation	NA	Y985C	0.33
UCEC	chr5	72197574	Missense_Mutation	rs200451397	E1407K	0.33
UCEC	chr5	72199584	Missense_Mutation	NA	R2077C	0.37
UCEC	chr5	72186726	Missense_Mutation	novel	N161T	0.4
UCEC	chr5	72203664	Missense_Mutation	novel	V2372I	0.23
UCEC	chr5	72194812	Missense_Mutation	NA	R486Q	0.49
UCEC	chr5	72195422	Silent	NA	K689K	0.44
UCEC	chr5	72197898	Nonsense_Mutation	NA	E1515*	0.15
UCEC	chr5	72195270	Frame_Shift_Del	novel	*K640Rfs5**	0.15
UCEC	chr5	72198467	Silent	novel	P1704P	0.33
UCEC	chr5	72195950	Missense_Mutation	rs559186362	E865D	0.45
UCEC	chr5	72198609	Missense_Mutation	rs569299339	D1752N	0.45
UCEC	chr5	72194485	Missense_Mutation	NA	S377I	0.42
UCEC	chr5	72195470	Silent	rs766902322	P705P	0.42
UCEC	chr5	72195575	Missense_Mutation	NA	K740N	0.32
UCEC	chr5	72196699	Missense_Mutation	novel	A1115V	0.4
UCEC	chr5	72197136	Missense_Mutation	NA	P1261S	0.28
UCEC	chr5	72194224	Missense_Mutation	novel	R290I	0.4
UCEC	chr5	72194882	Missense_Mutation	rs763989865	D509E	0.19
UCEC	chr5	72194781	Frame_Shift_Ins	novel	*H476Lfs35**	0.11
UCEC	chr5	72195694	Missense_Mutation	NA	G780V	0.27
UCEC	chr5	72197763	Nonsense_Mutation	NA	E1470*	0.11
UCEC	chr5	72198304	Missense_Mutation	NA	G1650D	0.19
UCEC	chr5	72199748	Silent	rs149330290	P2131P	0.15
UCEC	chr5	72199988	Silent	rs201776246	S2211S	0.23
UCEC	chr5	72200300	Silent	NA	E2315E	0.2
UCEC	chr5	72199250	Frame_Shift_Del	NA	*E1968Kfs2**	0.53
UCEC	chr5	72197981	Silent	rs141224742	T1542T	0.18
UCEC	chr5	72199608	Missense_Mutation	NA	V2085M	0.14
UCEC	chr5	72196250	Silent	rs193173542	S965S	0.09
UCEC	chr5	72196368	Missense_Mutation	rs781144386	D1005N	0.22
UCEC	chr5	72196785	Missense_Mutation	novel	S1144C	0.08
UCEC	chr5	72196786	Missense_Mutation	novel	S1144N	0.06
UCEC	chr5	72197634	Missense_Mutation	novel	S1427R	0.15
UCEC	chr5	72198316	Missense_Mutation	novel	P1654H	0.27
UCEC	chr5	72197223	Missense_Mutation	novel	A1290T	0.48
UCEC	chr5	72197871	Missense_Mutation	NA	D1506Y	0.52
UCEC	chr5	72205294	3'UTR	novel		0.58
UCEC	chr5	72194166	Missense_Mutation	NA	D271N	0.6
UCEC	chr5	72196832	Silent	rs183960902	F1159F	0.4
UCEC	chr5	72198395	Silent	novel	T1680T	0.57
UCEC	chr5	72195410	Nonsense_Mutation	novel	*K686Gfs7**	0.04
UCEC	chr5	72195595	Missense_Mutation	novel	S747F	0.24
UCEC	chr5	72198869	Silent	rs766462360	F1838F	0.29
UCEC	chr5	72206553	3'UTR	novel		0.53
UCEC	chr5	72183774	Silent	novel	V106V	0.39
UCEC	chr5	72194046	Missense_Mutation	novel	E231K	0.13
UCEC	chr5	72194614	Missense_Mutation	novel	L420R	0.5
UCEC	chr5	72198731	Silent	novel	S1792S	0.31
UCEC	chr5	72198822	Missense_Mutation	novel	D1823Y	0.13
UCEC	chr5	72205105	Missense_Mutation	novel	D2425Y	0.44
UCEC	chr5	72206307	3'UTR	novel		0.2
UCEC	chr5	72195740	Silent	rs777693283	V795V	0.44
UCEC	chr5	72196252	Missense_Mutation	novel	A966V	0.37
UCEC	chr5	72197223	Missense_Mutation	novel	A1290T	0.47
UCEC	chr5	72196465	Frame_Shift_Del	NA	*M1039Wfs7**	0.06
UCEC	chr5	72195027	Missense_Mutation	novel	R558C	0.36
UCEC	chr5	72196778	Silent	rs756150263	D1141D	0.42
UCEC	chr5	72197243	Silent	rs112410183	P1296P	0.34
UCEC	chr5	72199770	Missense_Mutation	novel	G2139C	0.38
UCEC	chr5	72206055	3'UTR	novel		0.1
UCEC	chr5	72186720	Missense_Mutation	NA	F159Y	0.41
UCEC	chr5	72200083	Missense_Mutation	NA	T2243N	0.4
UCEC	chr5	72197265	Nonsense_Mutation	novel	E1304*	0.24
UCEC	chr5	72197643	Nonsense_Mutation	novel	E1430*	0.31
UCEC	chr5	72198683	Missense_Mutation	novel	E1776D	0.27
UCEC	chr5	72197763	Nonsense_Mutation	NA	E1470*	0.37
UCEC	chr5	72200190	Nonsense_Mutation	novel	E2279*	0.59
UCEC	chr5	72206088	3'UTR	novel		0.43
UCEC	chr5	72186685	Silent	novel	T147T	0.22
UCEC	chr5	72197795	Silent	novel	D1480D	0.27
UCEC	chr5	72198795	Missense_Mutation	novel	C1814R	0.23
UCEC	chr5	72199585	Missense_Mutation	rs34160030	R2077H	0.36
UCEC	chr5	72206556	3'UTR	novel		0.38
UCEC	chr5	72196465	Frame_Shift_Del	NA	*M1039Wfs7**	0.09
UCEC	chr5	72196382	Missense_Mutation	NA	E1009D	0.45
UCEC	chr5	72196703	Silent	novel	T1116T	0.16
UCEC	chr5	72197779	Missense_Mutation	novel	E1475A	0.36
UCEC	chr5	72206124	3'UTR	novel		0.51
UCEC	chr5	72206357	3'UTR	novel		0.38
UCEC	chr5	72195945	Missense_Mutation	rs756153336	E864K	0.31
UCEC	chr5	72200240	Silent	novel	S2295S	0.38
UCEC	chr5	72196023	Missense_Mutation	rs139604402	E890K	0.18
UCEC	chr5	72199608	Missense_Mutation	NA	V2085M	0.06
UCEC	chr5	72194972	Silent	NA	A539A	0.45
UCEC	chr5	72199772	Silent	NA	G2139G	0.49
UCEC	chr5	72200332	Missense_Mutation	rs145292264	A2326V	0.71
UCEC	chr5	72196785	Missense_Mutation	novel	S1144C	0.08
UCEC	chr5	72196786	Missense_Mutation	novel	S1144N	0.08
UCEC	chr5	72197898	Nonsense_Mutation	NA	E1515*	0.3
UCEC	chr5	72198494	Silent	NA	Q1713Q	0.28
UCEC	chr5	72199981	Missense_Mutation	NA	S2209N	0.46
UCEC	chr5	72195282	Missense_Mutation	novel	K643Q	0.25
UCEC	chr5	72195975	Missense_Mutation	rs780650498	E874K	0.59
UCEC	chr5	72196382	Missense_Mutation	NA	E1009D	0.31
UCEC	chr5	72197384	Missense_Mutation	novel	E1343D	0.11
UCEC	chr5	72199907	Silent	rs771765179	S2184S	0.22
UCEC	chr5	72199249	Frame_Shift_Ins	rs775893760	*E1968Rfs8**	0.27
UCEC	chr5	72195975	Missense_Mutation	rs780650498	E874K	0.24
UCEC	chr5	72196832	Silent	rs183960902	F1159F	0.25
UCEC	chr5	72197265	Nonsense_Mutation	novel	E1304*	0.33
UCEC	chr5	72197910	Missense_Mutation	novel	M1519L	0.13
UCEC	chr5	72206362	3'UTR	novel		0.47
UCEC	chr5	72193909	Missense_Mutation	novel	S185N	0.43
UCEC	chr5	72197558	Silent	rs752177471	P1401P	0.27
UCEC	chr5	72199325	Silent	novel	G1990G	0.5
UCEC	chr5	72199748	Silent	rs149330290	P2131P	0.43
UCEC	chr5	72196119	Missense_Mutation	rs773432814	D922N	0.31
UCEC	chr5	72199830	Missense_Mutation	novel	D2159N	0.39
UCEC	chr5	72194796	Missense_Mutation	novel	A481T	0.44
UCEC	chr5	72195660	Missense_Mutation	novel	D769Y	0.5
UCEC	chr5	72195950	Missense_Mutation	rs559186362	E865D	0.47
UCEC	chr5	72196619	Missense_Mutation	novel	E1088D	0.29
UCEC	chr5	72199877	Silent	rs557929033	A2174A	0.53
UCEC	chr5	72205499	3'UTR	novel		0.45
UCEC	chr5	72197163	Frame_Shift_Ins	NA	*L1272Pfs3**	0.29
UCEC	chr5	72198545	Silent	rs758570511	P1730P	0.29
UCEC	chr5	72197126	Silent	rs757277389	P1257P	0.37
UCEC	chr5	72183750	Missense_Mutation	novel	K98N	0.32
UCEC	chr5	72193977	Missense_Mutation	NA	D208Y	0.28
UCEC	chr5	72194801	Silent	novel	E482E	0.48
UCEC	chr5	72196593	Nonsense_Mutation	NA	E1080*	0.38
UCEC	chr5	72195819	Nonsense_Mutation	NA	E822*	0.34
UCEC	chr5	72197265	Nonsense_Mutation	novel	E1304*	0.34
UCEC	chr5	72198355	Frame_Shift_Ins	novel	*D1668Rfs14**	0.44
UCEC	chr5	72195358	Missense_Mutation	NA	P668H	0.34
UCEC	chr5	72194337	Missense_Mutation	NA	I328F	0.27
UCEC	chr5	72196198	Missense_Mutation	NA	T948I	0.23
UCEC	chr5	72197265	Nonsense_Mutation	novel	E1304*	0.06
UCEC	chr5	72198057	Missense_Mutation	NA	D1568N	0.15
UCEC	chr5	72198495	Missense_Mutation	rs371216590	D1714Y	0.09
UCEC	chr5	72115725	Missense_Mutation	novel	I71S	0.09
UCEC	chr5	72195795	Missense_Mutation	novel	I814L	0.16
UCEC	chr5	72198870	Missense_Mutation	rs754067983	D1839N	0.19
UCEC	chr5	72193865	Splice_Site	novel	X171_splice	0.59
UCEC	chr5	72194172	Missense_Mutation	novel	A273T	0.29
UCEC	chr5	72195869	Missense_Mutation	novel	K838N	0.32
UCEC	chr5	72196936	Missense_Mutation	novel	A1194V	0.3
UCEC	chr5	72197504	Silent	rs376974397	P1383P	0.29
UCEC	chr5	72203635	Missense_Mutation	novel	Y2362C	0.05
UCEC	chr5	72195275	Silent	novel	K640K	0.38
UCEC	chr5	72198625	Missense_Mutation	novel	R1757I	0.29
UCEC	chr5	72203802	Splice_Site	novel	X2417_splice	0.44
UCEC	chr5	72194101	Frame_Shift_Ins	novel	*T250Ffs9**	0.07
UCEC	chr5	72194781	Frame_Shift_Ins	novel	*H476Lfs38**	0.13
UCEC	chr5	72195602	Frame_Shift_Del	NA	*K751Nfs5**	0.33
UCEC	chr5	72196265	Frame_Shift_Del	novel	*T972Lfs74**	0.5
UCEC	chr5	72196833	Missense_Mutation	rs773567258	V1160I	0.31
UCEC	chr5	72194665	Missense_Mutation	NA	F437C	0.44
UCEC	chr5	72195575	Missense_Mutation	NA	K740N	0.39
UCEC	chr5	72195575	Missense_Mutation	NA	K740N	0.36
UCEC	chr5	72196877	Silent	novel	Y1174Y	0.57
UCEC	chr5	72200094	Missense_Mutation	NA	K2247Q	0.26
UCEC	chr5	72196900	Missense_Mutation	rs779963708	P1182L	0.38
UCEC	chr5	72198191	Missense_Mutation	NA	E1612D	0.28
UCEC	chr5	72198300	Missense_Mutation	NA	F1649V	0.26
UCEC	chr5	72194997	Missense_Mutation	novel	A548T	0.39
UCEC	chr5	72198482	Silent	rs367827530	P1709P	0.38
UCEC	chr5	72205329	3'UTR	novel		0.29
UCEC	chr5	72183823	Missense_Mutation	NA	E123K	0.21
UCEC	chr5	72194485	Missense_Mutation	novel	S377N	0.24
UCEC	chr5	72195802	Missense_Mutation	novel	A816V	0.34
UCEC	chr5	72196119	Missense_Mutation	rs773432814	D922N	0.26
UCEC	chr5	72197342	Silent	rs779417636	G1329G	0.24
UCEC	chr5	72197631	Missense_Mutation	rs535672589	E1426K	0.21
UCEC	chr5	72198861	Missense_Mutation	novel	V1836L	0.31
UCEC	chr5	72198863	Silent	novel	V1836V	0.3
UCEC	chr5	72199590	Missense_Mutation	novel	D2079N	0.53
UCEC	chr5	72200198	Silent	rs768981407	S2281S	0.25
UCEC	chr5	72200348	Silent	rs530617482	S2331S	0.22
UCEC	chr5	72196950	Missense_Mutation	rs746637456	D1199N	0.45
UCEC	chr5	72198782	Missense_Mutation	novel	E1809D	0.14
UCEC	chr5	72200235	Nonsense_Mutation	novel	E2294*	0.5
UCEC	chr5	72196784	Frame_Shift_Ins	novel	*S1144Yfs30**	0.05
UCEC	chr5	72194592	Frame_Shift_Ins	novel	*M415Nfs5**	0.28
UCEC	chr5	72195408	Frame_Shift_Del	novel	*E687Rfs35**	0.12
UCEC	chr5	72197217	Missense_Mutation	novel	V1288F	0.1
UCEC	chr5	72193317	Intron	novel		0.29
UCEC	chr5	72194684	Silent	novel	G443G	0.42
UCEC	chr5	72199453	Missense_Mutation	rs756620120	R2033Q	0.33
UCEC	chr5	72206017	3'UTR	novel		0.35
UCEC	chr5	72200239	Missense_Mutation	novel	S2295Y	0.34
UCEC	chr5	72205119	Missense_Mutation	rs755065732	M2429I	0.13
UCS	chr5	72193946	Missense_Mutation	novel	K197N	0.4
UCS	chr5	72196101	Missense_Mutation	NA	E916K	0.05
UCS	chr5	72197871	Missense_Mutation	NA	D1506Y	0.36
UCS	chr5	72198578	Silent	rs550175931	I1741I	0.39

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BRCA	DEL	0.2417	1.1352e-11
CHOL	DEL	0.2222	0.16947
LUSC	DEL	0.6527	0.002071
MESO	DEL	0.1379	0.20184
OV	DEL	0.6891	3.6941e-88
PAAD	DEL	0.1304	0.0001774
PRAD	DEL	0.1728	2.112e-26
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
STAD	0.004	Kaplan-Meier Survival Analysis
UCS	0.0031	Kaplan-Meier Survival Analysis
SKCM	0.0046	Kaplan-Meier Survival Analysis
PAAD	0.0011	Kaplan-Meier Survival Analysis
BLCA	0.0001	Kaplan-Meier Survival Analysis
LAML	0.05	Kaplan-Meier Survival Analysis
GBM	0.037	Kaplan-Meier Survival Analysis
LGG	0.0035	Kaplan-Meier Survival Analysis
UVM	0.00012	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742