EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000132182 (Gene tree)
Gene ID: 23225
Gene Symbol: NUP210
Alias: GP210|POM210|FLJ22389|KIAA0906
Full Name: nucleoporin 210
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 104,090 bases
Position: chr3:13,316,230-13,420,319
Accession: 30052
RBP type: non-canonical RBP
Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000479519	NUP210-203	1312	-	-	- (aa)	-	-
ENST00000254508	NUP210-201	7193	XM_024453411	ENSP00000254508	1887 (aa)	XP_024309179	Q8TEM1
ENST00000485755	NUP210-204	474	-	-	- (aa)	-	-
ENST00000420141	NUP210-202	3134	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000132182's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000132182	Alcoholism	2.33538e-005	22978509
ENSG00000132182	Alcoholism	2.33538e-005	22978509
ENSG00000132182	Alcoholism	1.89895e-005	22978509
ENSG00000132182	Alcoholism	4.10631e-005	22978509
ENSG00000132182	Alcoholism	9.63998e-005	22978509
ENSG00000132182	Bronchodilator Agents	4E-6	26634245
ENSG00000132182	Lung Volume Measurements	4E-6	26634245
ENSG00000132182	Bronchodilator Agents	4E-6	26634245
ENSG00000132182	Lung Volume Measurements	4E-6	26634245
ENSG00000132182	Bronchodilator Agents	4E-6	26634245
ENSG00000132182	Lung Volume Measurements	4E-6	26634245

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000132182	rs73018809	3	13329174	T	Coronary artery disease in type 1 diabetes	29695241	[NR]	3.5	EFO_0001359\|EFO_0000378
ENSG00000132182	rs3796320	3	13376883	A	Self-reported math ability (MTAG)	30038396	[0.0088-0.0182] unit increase	0.0135	EFO_0004875
ENSG00000132182	rs9845966	3	13391658	T	Body mass index	26426971	unit increase	0.015592072	EFO_0004340
ENSG00000132182	rs1048620	3	13316630	?	Body mass index	30595370			EFO_0004340

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000132182's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000132182	NUP210	99	84.824	ENSMUSG00000030091	Nup210	99	85.116	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005635	nuclear envelope	-	TAS	Component
GO:0005643	nuclear pore	21873635.	IBA	Component
GO:0005789	endoplasmic reticulum membrane	-	IEA	Component
GO:0006110	regulation of glycolytic process	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006409	tRNA export from nucleus	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016032	viral process	-	TAS	Process
GO:0016925	protein sumoylation	-	TAS	Process
GO:0019083	viral transcription	-	TAS	Process
GO:0031965	nuclear membrane	-	IEA	Component
GO:0043657	host cell	-	IEA	Component
GO:0046983	protein dimerization activity	-	IEA	Function
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process
GO:0075733	intracellular transport of virus	-	TAS	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr3	13327436	Missense_Mutation	novel	D1430H	0.31
BLCA	chr3	13373845	Nonsense_Mutation	novel	W487*	0.39
BLCA	chr3	13360314	Missense_Mutation	NA	Q704K	0.17
BLCA	chr3	13375580	Missense_Mutation	novel	I452S	0.11
BLCA	chr3	13328918	Missense_Mutation	novel	S1380C	0.07
BLCA	chr3	13376311	Missense_Mutation	NA	L425V	0.09
BLCA	chr3	13319760	Splice_Region	novel		0.28
BLCA	chr3	13335604	Silent	novel	I1231I	0.14
BLCA	chr3	13377488	Missense_Mutation	novel	D374N	0.17
BLCA	chr3	13388406	Missense_Mutation	novel	S194L	0.27
BLCA	chr3	13336904	Silent	novel	V1189V	0.27
BLCA	chr3	13351939	Silent	rs773463749	L925L	0.21
BLCA	chr3	13322266	Silent	NA	Q1614Q	0.61
BLCA	chr3	13397413	Missense_Mutation	novel	E127V	0.36
BLCA	chr3	13325925	Missense_Mutation	NA	S1505L	0.08
BLCA	chr3	13353634	Missense_Mutation	novel	A850T	0.1
BLCA	chr3	13391297	Missense_Mutation	novel	F149L	0.24
BLCA	chr3	13360405	Silent	rs760475344	L673L	0.48
BLCA	chr3	13341823	Silent	rs781125186	I1051I	0.19
BLCA	chr3	13335475	Silent	novel	L1274L	0.41
BLCA	chr3	13373730	Silent	rs202170701	F525F	0.4
BLCA	chr3	13325907	Missense_Mutation	NA	S1511L	0.21
BLCA	chr3	13339883	Missense_Mutation	novel	E1148K	0.2
BLCA	chr3	13397385	Missense_Mutation	novel	E136D	0.15
BLCA	chr3	13351927	Silent	novel	T929T	0.89
BLCA	chr3	13339932	Silent	rs750190590	L1131L	0.41
BLCA	chr3	13375637	Missense_Mutation	novel	G433A	0.07
BLCA	chr3	13321594	Missense_Mutation	novel	E1719D	0.37
BRCA	chr3	13375631	Missense_Mutation	novel	V435A	0.07
BRCA	chr3	13323380	Missense_Mutation	novel	Q1566P	0.08
BRCA	chr3	13327391	Missense_Mutation	rs372138569	V1445I	0.41
BRCA	chr3	13323339	Missense_Mutation	NA	A1580T	0.2
BRCA	chr3	13322337	Missense_Mutation	rs374396330	E1591K	0.22
BRCA	chr3	13323412	Silent	NA	Q1555Q	0.14
BRCA	chr3	13335610	Splice_Region	rs770494503	A1229A	0.27
BRCA	chr3	13379701	Nonsense_Mutation	novel	Q280*	0.33
BRCA	chr3	13358221	Splice_Site	NA	X776_splice	0.56
BRCA	chr3	13342031	Silent	novel	L1019L	0.2
BRCA	chr3	13360354	Silent	rs756247776	I690I	0.06
BRCA	chr3	13323372	Missense_Mutation	NA	F1569V	0.27
BRCA	chr3	13317639	3'UTR	novel		0.25
BRCA	chr3	13365949	Silent	NA	L643L	0.28
BRCA	chr3	13388321	Silent	NA	I222I	0.11
BRCA	chr3	13335506	Missense_Mutation	novel	S1264L	0.08
BRCA	chr3	13328817	Missense_Mutation	novel	D1414N	0.14
CESC	chr3	13322281	Silent	rs777191665	I1609I	0.25
CESC	chr3	13376304	Missense_Mutation	rs372026570	S427F	0.47
CESC	chr3	13339983	Silent	NA	I1114I	0.13
CESC	chr3	13358329	Missense_Mutation	novel	V741M	0.4
CESC	chr3	13378974	Missense_Mutation	rs765447965	R328H	0.38
CESC	chr3	13319769	Missense_Mutation	rs748602696	G1793S	0.14
CHOL	chr3	13341792	Missense_Mutation	novel	N1062H	0.59
COAD	chr3	13351810	Intron	novel		0.24
COAD	chr3	13354089	Missense_Mutation	rs201758204	R783C	0.34
COAD	chr3	13376349	Missense_Mutation	novel	R412K	0.09
COAD	chr3	13371999	Missense_Mutation	NA	A541S	0.43
COAD	chr3	13351884	Missense_Mutation	rs433032	A944T	0.36
COAD	chr3	13399757	Missense_Mutation	rs755992121	R91H	0.32
COAD	chr3	13397390	Frame_Shift_Del	rs773055247	*L135Wfs3**	0.34
COAD	chr3	13376424	Missense_Mutation	rs141201901	R387Q	0.15
COAD	chr3	13365957	Missense_Mutation	NA	L641M	0.29
COAD	chr3	13399758	Missense_Mutation	NA	R91C	0.25
COAD	chr3	13340289	Missense_Mutation	NA	P1080T	0.39
COAD	chr3	13354140	Intron	novel		0.39
COAD	chr3	13319850	Missense_Mutation	novel	L1766M	0.26
COAD	chr3	13371898	Silent	rs754885907	S574S	0.38
COAD	chr3	13358314	Missense_Mutation	NA	C746R	0.16
COAD	chr3	13335512	Missense_Mutation	novel	P1262L	0.04
COAD	chr3	13337870	Silent	rs771153628	R1173R	0.5
COAD	chr3	13397417	Missense_Mutation	rs758003408	R126C	0.36
COAD	chr3	13330592	Silent	rs775583860	P1326P	0.47
COAD	chr3	13397390	Frame_Shift_Del	rs773055247	*L135Wfs3**	0.19
COAD	chr3	13317701	Missense_Mutation	novel	P1882T	0.18
COAD	chr3	13330609	Missense_Mutation	rs752278223	R1321C	0.18
COAD	chr3	13373822	Missense_Mutation	NA	A495T	0.27
COAD	chr3	13335502	Frame_Shift_Del	NA	*Q1266Sfs28**	0.4
COAD	chr3	13339918	Missense_Mutation	NA	G1136D	0.31
COAD	chr3	13377463	Missense_Mutation	NA	V382A	0.47
COAD	chr3	13321631	Missense_Mutation	novel	S1707Y	0.24
COAD	chr3	13336859	Silent	NA	A1204A	0.68
COAD	chr3	13335512	Missense_Mutation	NA	P1262H	0.35
COAD	chr3	13351884	Missense_Mutation	rs433032	A944T	0.25
DLBC	chr3	13337881	Missense_Mutation	rs772578384	V1170M	0.43
DLBC	chr3	13386359	Silent	novel	L245L	0.17
ESCA	chr3	13317706	Nonsense_Mutation	novel	W1880*	0.15
ESCA	chr3	13376356	Missense_Mutation	rs766961777	R410C	0.2
ESCA	chr3	13337912	Silent	rs202204981	L1159L	0.42
ESCA	chr3	13330536	Missense_Mutation	novel	M1345K	0.43
ESCA	chr3	13388307	Missense_Mutation	novel	Y227C	0.28
ESCA	chr3	13321725	Missense_Mutation	novel	F1676V	0.28
ESCA	chr3	13319814	Missense_Mutation	rs750230647	A1778T	0.46
ESCA	chr3	13376360	Silent	novel	Y408Y	0.41
ESCA	chr3	13388348	Silent	rs773902822	T213T	0.38
GBM	chr3	13325879	Silent	novel	P1520P	0.5
GBM	chr3	13391243	Silent	NA	A167A	0.28
GBM	chr3	13319926	Silent	novel	G1740G	0.09
GBM	chr3	13321731	Missense_Mutation	novel	S1674G	0.09
GBM	chr3	13336801	Missense_Mutation	novel	G1224W	0.33
GBM	chr3	13358287	Missense_Mutation	rs775722678	A755T	0.23
GBM	chr3	13358323	Missense_Mutation	novel	K743Q	0.17
GBM	chr3	13379688	Missense_Mutation	novel	Q284P	0.48
GBM	chr3	13360414	Silent	novel	P670P	0.2
GBM	chr3	13358263	Missense_Mutation	novel	L763M	0.07
GBM	chr3	13340019	Silent	rs778365730	G1102G	0.07
GBM	chr3	13354042	Silent	novel	R798R	0.35
GBM	chr3	13328778	Missense_Mutation	novel	T1427S	0.06
GBM	chr3	13375585	Missense_Mutation	novel	I450M	0.05
GBM	chr3	13337844	Missense_Mutation	NA	G1182D	0.09
GBM	chr3	13360324	Silent	novel	S700S	0.28
GBM	chr3	13342060	Missense_Mutation	NA	L1010F	0.06
HNSC	chr3	13379596	Missense_Mutation	rs149916127	L315V	0.1
HNSC	chr3	13340025	Silent	rs112614885	S1100S	0.26
HNSC	chr3	13335546	Missense_Mutation	novel	T1251A	0.19
HNSC	chr3	13397451	Missense_Mutation	novel	D114E	0.28
HNSC	chr3	13327324	Missense_Mutation	rs147955019	S1467L	0.19
HNSC	chr3	13325915	Missense_Mutation	novel	W1508C	0.17
HNSC	chr3	13328875	Silent	novel	V1394V	0.59
HNSC	chr3	13323386	Missense_Mutation	novel	P1564H	0.46
HNSC	chr3	13351859	Intron	novel		0.27
HNSC	chr3	13366000	Silent	rs771935308	H626H	0.21
KIRC	chr3	13388323	Missense_Mutation	NA	I222F	0.3
KIRP	chr3	13354163	Intron	novel		0.58
KIRP	chr3	13317589	3'UTR	novel		0.63
KIRP	chr3	13397380	Missense_Mutation	NA	K138R	0.3
KIRP	chr3	13358393	Splice_Region	NA	V719V	0.13
KIRP	chr3	13373870	Missense_Mutation	NA	H479Y	0.42
KIRP	chr3	13341746	Splice_Site	novel	X1076_splice	0.36
LAML	chr3	13336902	Missense_Mutation	novel	T1190I	0.07
LGG	chr3	13366058	Missense_Mutation	novel	G607D	0.08
LGG	chr3	13321758	Missense_Mutation	NA	L1665V	0.29
LGG	chr3	13336858	Missense_Mutation	rs762894928	V1205M	0.37
LGG	chr3	13340287	Silent	rs771819748	P1080P	0.13
LGG	chr3	13351862	Intron	novel		0.23
LGG	chr3	13371875	Missense_Mutation	novel	A582V	0.38
LIHC	chr3	13351803	Intron	novel		0.23
LIHC	chr3	13327241	Missense_Mutation	rs199638243	A1495T	0.17
LIHC	chr3	13341818	Missense_Mutation	NA	Q1053L	0.3
LIHC	chr3	13360365	Missense_Mutation	novel	T687S	0.38
LIHC	chr3	13335478	Silent	novel	E1273E	0.21
LIHC	chr3	13354218	Intron	novel		0.91
LIHC	chr3	13360319	Missense_Mutation	NA	N702S	0.88
LIHC	chr3	13371850	Silent	rs767996831	V590V	0.34
LUAD	chr3	13319774	Missense_Mutation	novel	G1791V	0.38
LUAD	chr3	13360454	Missense_Mutation	NA	G657V	0.71
LUAD	chr3	13322218	Silent	novel	V1630V	0.22
LUAD	chr3	13321783	Missense_Mutation	novel	K1656N	0.16
LUAD	chr3	13335524	Missense_Mutation	novel	K1258R	0.07
LUAD	chr3	13378947	Missense_Mutation	NA	N337S	0.69
LUAD	chr3	13328800	Silent	novel	H1419H	0.4
LUAD	chr3	13319254	Missense_Mutation	novel	A1819T	0.5
LUAD	chr3	13358289	Frame_Shift_Ins	novel	*L754Pfs53**	0.09
LUAD	chr3	13376390	Silent	novel	E398E	0.16
LUAD	chr3	13322320	Missense_Mutation	novel	Q1596H	0.33
LUAD	chr3	13325881	Missense_Mutation	novel	P1520S	0.3
LUAD	chr3	13375595	Missense_Mutation	NA	E447V	0.21
LUAD	chr3	13323336	Missense_Mutation	novel	V1581L	0.21
LUAD	chr3	13327232	Silent	novel	L1498L	0.21
LUAD	chr3	13323382	Missense_Mutation	NA	I1565M	0.36
LUAD	chr3	13420110	Frame_Shift_Ins	novel	*A40Gfs5**	0.35
LUAD	chr3	13399797	Nonsense_Mutation	NA	Q78*	0.44
LUAD	chr3	13327343	Missense_Mutation	NA	A1461S	0.18
LUAD	chr3	13386367	Missense_Mutation	NA	N242T	0.08
LUAD	chr3	13352154	Missense_Mutation	rs761349540	I887V	0.74
LUAD	chr3	13353661	Splice_Site	NA	X841_splice	0.57
LUAD	chr3	13319923	Missense_Mutation	novel	W1741C	0.08
LUAD	chr3	13397372	Missense_Mutation	NA	A141S	0.18
LUAD	chr3	13319250	Missense_Mutation	NA	G1820V	0.5
LUAD	chr3	13391218	Missense_Mutation	NA	A176T	0.19
LUAD	chr3	13386351	Silent	NA	P247P	0.13
LUAD	chr3	13339936	Missense_Mutation	novel	G1130V	0.25
LUAD	chr3	13373750	Missense_Mutation	NA	V519L	0.65
LUSC	chr3	13319881	Silent	novel	A1755A	0.47
LUSC	chr3	13352173	Silent	novel	L880L	0.32
LUSC	chr3	13375573	Silent	NA	I454I	0.16
LUSC	chr3	13376393	Silent	novel	F397F	0.3
LUSC	chr3	13379662	Nonsense_Mutation	novel	E293*	0.43
LUSC	chr3	13339967	Missense_Mutation	NA	A1120S	0.35
LUSC	chr3	13360354	Silent	rs756247776	I690I	0.23
LUSC	chr3	13353551	Splice_Site	novel	X874_splice	0.17
LUSC	chr3	13353589	Nonsense_Mutation	NA	E865*	0.29
LUSC	chr3	13330471	Missense_Mutation	novel	V1367F	0.15
LUSC	chr3	13358303	Silent	rs768612746	P749P	0.11
LUSC	chr3	13376392	Missense_Mutation	novel	E398Q	0.25
LUSC	chr3	13360284	Missense_Mutation	novel	A714S	0.17
LUSC	chr3	13399758	Missense_Mutation	NA	R91C	0.54
LUSC	chr3	13371978	Missense_Mutation	rs762599030	R548C	0.29
LUSC	chr3	13339989	Silent	NA	F1112F	0.13
OV	chr3	13323394	Missense_Mutation	novel	H1561Q	0.05
OV	chr3	13366048	Silent	NA	V610V	0.54
OV	chr3	13328856	Missense_Mutation	novel	T1401A	0.17
OV	chr3	13336808	Silent	NA	D1221D	0.77
OV	chr3	13323354	Missense_Mutation	novel	S1575T	0.06
OV	chr3	13322292	Missense_Mutation	rs774007395	E1606Q	0.12
OV	chr3	13343300	Missense_Mutation	novel	H947N	0.63
OV	chr3	13323413	Missense_Mutation	novel	Q1555P	0.11
OV	chr3	13376404	Missense_Mutation	NA	A394S	0.39
OV	chr3	13366037	Missense_Mutation	rs766934796	A614G	0.19
PAAD	chr3	13319858	Missense_Mutation	novel	S1763F	0.16
PAAD	chr3	13339881	Missense_Mutation	novel	E1148D	0.25
PAAD	chr3	13377517	Missense_Mutation	rs555632447	R364H	0.15
PAAD	chr3	13335562	Silent	novel	G1245G	0.1
PRAD	chr3	13340288	Missense_Mutation	novel	P1080L	0.46
PRAD	chr3	13397386	Missense_Mutation	NA	E136G	0.34
PRAD	chr3	13319908	Silent	novel	T1746T	0.35
PRAD	chr3	13335570	Missense_Mutation	novel	V1243M	0.11
PRAD	chr3	13339971	Silent	rs762682844	S1118S	0.45
PRAD	chr3	13377455	Splice_Site	novel	X384_splice	0.38
READ	chr3	13373838	Silent	rs149524649	S489S	0.41
READ	chr3	13397414	Missense_Mutation	NA	E127K	0.21
READ	chr3	13365993	Missense_Mutation	rs141744656	V629I	0.27
READ	chr3	13378944	Missense_Mutation	novel	S338N	0.22
READ	chr3	13317782	Splice_Site	novel	X1855_splice	0.27
READ	chr3	13341750	Nonsense_Mutation	novel	E1076*	0.21
SARC	chr3	13336798	Missense_Mutation	rs561241593	R1225W	0.07
SKCM	chr3	13373774	Missense_Mutation	NA	F511V	0.19
SKCM	chr3	13337873	Silent	NA	I1172I	0.26
SKCM	chr3	13379565	Missense_Mutation	NA	R325K	0.22
SKCM	chr3	13325807	Silent	novel	R1544R	0.28
SKCM	chr3	13340290	Silent	novel	P1079P	0.1
SKCM	chr3	13378926	Missense_Mutation	novel	E344G	0.27
SKCM	chr3	13340024	Missense_Mutation	rs200679883	E1101K	0.51
SKCM	chr3	13360373	Missense_Mutation	novel	A684V	0.31
SKCM	chr3	13336789	Missense_Mutation	NA	E1228K	0.31
SKCM	chr3	13336810	Missense_Mutation	novel	D1221N	0.3
SKCM	chr3	13336811	Silent	novel	L1220L	0.3
SKCM	chr3	13351839	Intron	novel		0.39
SKCM	chr3	13340026	Missense_Mutation	novel	S1100F	0.15
SKCM	chr3	13328932	Silent	NA	S1375S	0.43
SKCM	chr3	13336789	Missense_Mutation	NA	E1228K	0.59
SKCM	chr3	13342060	Missense_Mutation	NA	L1010F	0.43
SKCM	chr3	13366091	Missense_Mutation	NA	G596E	0.49
SKCM	chr3	13388317	Missense_Mutation	NA	E224K	0.59
SKCM	chr3	13397430	Silent	rs768699678	I121I	0.58
SKCM	chr3	13321784	Missense_Mutation	NA	K1656T	0.49
SKCM	chr3	13323333	Missense_Mutation	rs778261437	G1582R	0.35
SKCM	chr3	13328822	Missense_Mutation	novel	S1412F	0.26
SKCM	chr3	13319947	Silent	rs374239607	F1733F	0.22
SKCM	chr3	13321779	Silent	NA	L1658L	0.11
SKCM	chr3	13322329	Silent	NA	T1593T	0.31
SKCM	chr3	13339926	Silent	rs535350911	I1133I	0.22
SKCM	chr3	13340284	Silent	NA	F1081F	0.17
SKCM	chr3	13358248	Missense_Mutation	NA	P768S	0.2
SKCM	chr3	13351839	Intron	novel		0.65
SKCM	chr3	13323311	Missense_Mutation	novel	R1589K	0.34
SKCM	chr3	13377472	Missense_Mutation	novel	K379T	0.08
SKCM	chr3	13323417	Missense_Mutation	novel	P1554S	0.38
SKCM	chr3	13325844	Missense_Mutation	novel	S1532F	0.35
SKCM	chr3	13342010	Silent	rs777414567	P1026P	0.23
SKCM	chr3	13352134	Silent	novel	E893E	0.2
SKCM	chr3	13337873	Silent	NA	I1172I	0.43
SKCM	chr3	13339926	Silent	rs535350911	I1133I	0.18
SKCM	chr3	13366020	Missense_Mutation	novel	L620F	0.31
SKCM	chr3	13375545	Missense_Mutation	NA	P464S	0.25
SKCM	chr3	13378955	Silent	novel	R334R	0.26
SKCM	chr3	13319947	Silent	rs374239607	F1733F	0.36
SKCM	chr3	13336841	Silent	NA	F1210F	0.26
SKCM	chr3	13336789	Missense_Mutation	NA	E1228K	0.35
SKCM	chr3	13339995	Silent	rs766596955	I1110I	0.14
SKCM	chr3	13353560	Silent	novel	K874K	0.46
SKCM	chr3	13351966	Silent	novel	I916I	0.37
SKCM	chr3	13323338	Missense_Mutation	NA	A1580V	0.43
SKCM	chr3	13378962	Missense_Mutation	NA	A332D	0.46
SKCM	chr3	13378950	Missense_Mutation	NA	P336L	0.26
SKCM	chr3	13335457	Silent	NA	V1280V	0.26
SKCM	chr3	13378928	Silent	rs759033945	V343V	0.28
SKCM	chr3	13335597	Missense_Mutation	NA	P1234S	0.33
SKCM	chr3	13340251	Silent	rs752404764	I1092I	0.54
SKCM	chr3	13352091	Missense_Mutation	novel	P908S	0.49
SKCM	chr3	13352092	Silent	novel	H907H	0.47
SKCM	chr3	13341776	Missense_Mutation	novel	R1067K	0.14
SKCM	chr3	13360397	Missense_Mutation	rs769477827	S676F	0.19
SKCM	chr3	13376426	Silent	NA	I386I	0.09
SKCM	chr3	13325844	Missense_Mutation	novel	S1532F	0.34
SKCM	chr3	13327235	Missense_Mutation	rs201064236	V1497I	0.3
SKCM	chr3	13330460	Splice_Region	novel	K1370K	0.43
SKCM	chr3	13391226	Missense_Mutation	novel	S173F	0.5
SKCM	chr3	13360323	Silent	NA	R701R	0.33
SKCM	chr3	13325852	Silent	rs750825095	A1529A	0.32
SKCM	chr3	13373766	Silent	NA	V513V	0.58
SKCM	chr3	13323326	Missense_Mutation	NA	R1584K	0.07
SKCM	chr3	13321656	Missense_Mutation	rs137867919	L1699F	0.34
SKCM	chr3	13321798	Silent	rs372142234	T1651T	0.16
SKCM	chr3	13327419	Silent	rs747355184	I1435I	0.39
SKCM	chr3	13397470	Missense_Mutation	rs200406823	R108H	0.44
SKCM	chr3	13323412	Silent	NA	Q1555Q	0.39
SKCM	chr3	13325912	Silent	NA	S1509S	0.43
SKCM	chr3	13373753	Missense_Mutation	rs780188310	D518N	0.52
SKCM	chr3	13319262	Missense_Mutation	rs745990443	A1816V	0.37
SKCM	chr3	13366088	Missense_Mutation	novel	R597K	0.47
SKCM	chr3	13327366	Missense_Mutation	novel	L1453R	0.18
SKCM	chr3	13330485	Missense_Mutation	NA	N1362S	0.34
SKCM	chr3	13317688	Missense_Mutation	NA	S1886F	0.42
SKCM	chr3	13388317	Missense_Mutation	NA	E224K	0.43
SKCM	chr3	13342061	Silent	rs138467259	F1009F	0.13
SKCM	chr3	13340292	Missense_Mutation	NA	P1079S	0.21
STAD	chr3	13330550	Silent	NA	L1340L	0.21
STAD	chr3	13343260	Missense_Mutation	rs768107728	D960G	0.14
STAD	chr3	13317675	3'UTR	novel		0.27
STAD	chr3	13325833	Missense_Mutation	NA	Y1536H	0.14
STAD	chr3	13330608	Missense_Mutation	rs767168252	R1321H	0.09
STAD	chr3	13388424	Missense_Mutation	NA	I188T	0.08
STAD	chr3	13386323	Missense_Mutation	rs747754565	T257A	0.21
STAD	chr3	13397390	Frame_Shift_Del	rs773055247	*L135Wfs3**	0.22
STAD	chr3	13339971	Silent	rs762682844	S1118S	0.25
STAD	chr3	13317663	3'UTR	novel		0.47
STAD	chr3	13319919	Missense_Mutation	novel	S1743G	0.34
STAD	chr3	13366081	Silent	rs199983406	P599P	0.34
STAD	chr3	13321734	Missense_Mutation	NA	S1673G	0.22
STAD	chr3	13325848	Missense_Mutation	NA	G1531R	0.22
STAD	chr3	13330591	Missense_Mutation	rs199836273	E1327K	0.37
STAD	chr3	13376424	Missense_Mutation	rs141201901	R387Q	0.35
STAD	chr3	13323338	Missense_Mutation	novel	A1580D	0.29
STAD	chr3	13335611	Missense_Mutation	rs773837178	A1229V	0.35
STAD	chr3	13342024	Nonsense_Mutation	rs778991781	R1022*	0.38
STAD	chr3	13360399	Silent	rs370837408	P675P	0.24
STAD	chr3	13375555	Silent	novel	I460I	0.06
STAD	chr3	13321606	Silent	rs748860972	P1715P	0.09
STAD	chr3	13328869	Silent	NA	V1396V	0.11
STAD	chr3	13321799	Missense_Mutation	NA	T1651M	0.3
STAD	chr3	13341834	Missense_Mutation	rs541868505	G1048S	0.18
STAD	chr3	13386390	Missense_Mutation	NA	E234D	0.25
STAD	chr3	13353589	Missense_Mutation	NA	E865Q	0.1
STAD	chr3	13420171	Missense_Mutation	NA	A19V	0.39
STAD	chr3	13325874	Missense_Mutation	rs369280391	T1522M	0.06
STAD	chr3	13366079	Frame_Shift_Del	novel	*P600Qfs11**	0.16
STAD	chr3	13351926	Missense_Mutation	rs372920147	A930T	0.26
STAD	chr3	13330583	Silent	NA	V1329V	0.31
STAD	chr3	13339917	Silent	NA	G1136G	0.06
STAD	chr3	13358241	Missense_Mutation	novel	L770Q	0.05
STAD	chr3	13327384	Missense_Mutation	NA	R1447H	0.23
STAD	chr3	13375508	Missense_Mutation	NA	I476T	0.29
STAD	chr3	13327418	Missense_Mutation	rs375252151	G1436R	0.42
STAD	chr3	13397390	Frame_Shift_Del	rs773055247	*L135Wfs3**	0.23
STAD	chr3	13330609	Missense_Mutation	rs752278223	R1321C	0.27
STAD	chr3	13322199	Missense_Mutation	novel	A1637S	0.49
STAD	chr3	13397390	Frame_Shift_Del	rs773055247	*L135Wfs3**	0.39
STAD	chr3	13339931	Missense_Mutation	NA	A1132T	0.23
STAD	chr3	13373802	Silent	NA	G501G	0.17
STAD	chr3	13351885	Silent	rs757176224	V943V	0.23
UCEC	chr3	13373778	Silent	rs113753878	I509I	0.23
UCEC	chr3	13341835	Silent	rs749341284	R1047R	0.25
UCEC	chr3	13360404	Missense_Mutation	rs200171517	E674K	0.3
UCEC	chr3	13323336	Missense_Mutation	rs199752879	V1581M	0.25
UCEC	chr3	13388429	Silent	rs199802592	T186T	0.23
UCEC	chr3	13335558	Missense_Mutation	NA	V1247I	0.25
UCEC	chr3	13317744	Silent	novel	L1867L	0.38
UCEC	chr3	13376321	Silent	novel	I421I	0.25
UCEC	chr3	13376413	Missense_Mutation	novel	V391M	0.07
UCEC	chr3	13353993	Missense_Mutation	novel	V815L	0.39
UCEC	chr3	13325848	Nonsense_Mutation	novel	G1531*	0.06
UCEC	chr3	13376424	Missense_Mutation	rs141201901	R387Q	0.43
UCEC	chr3	13376315	Silent	rs368251837	A423A	0.4
UCEC	chr3	13335612	Missense_Mutation	novel	A1229T	0.47
UCEC	chr3	13365966	Missense_Mutation	novel	A638T	0.3
UCEC	chr3	13317300	3'UTR	novel		0.19
UCEC	chr3	13325843	Silent	rs762362795	S1532S	0.42
UCEC	chr3	13351970	Missense_Mutation	rs369950513	R915H	0.47
UCEC	chr3	13360353	Missense_Mutation	rs752915398	G691S	0.44
UCEC	chr3	13391217	Missense_Mutation	rs780331826	A176V	0.39
UCEC	chr3	13339956	Silent	rs771863660	S1123S	0.24
UCEC	chr3	13322288	Missense_Mutation	NA	T1607I	0.15
UCEC	chr3	13335607	Silent	rs777356271	S1230S	0.21
UCEC	chr3	13319263	Missense_Mutation	rs375414642	A1816T	0.21
UCEC	chr3	13327295	Missense_Mutation	novel	A1477T	0.26
UCEC	chr3	13343202	Missense_Mutation	novel	Q979H	0.21
UCEC	chr3	13391211	Missense_Mutation	rs140229295	R178Q	0.21
UCEC	chr3	13319136	Silent	rs147461037	T1833T	0.2
UCEC	chr3	13321787	Missense_Mutation	rs569442945	R1655Q	0.43
UCEC	chr3	13319847	Missense_Mutation	novel	T1767A	0.12
UCEC	chr3	13330591	Missense_Mutation	rs199836273	E1327K	0.08
UCEC	chr3	13375572	Missense_Mutation	novel	T455A	0.18
UCEC	chr3	13399737	Missense_Mutation	novel	A98T	0.3
UCEC	chr3	13321775	Missense_Mutation	novel	S1659I	0.26
UCEC	chr3	13366021	Silent	rs760524898	T619T	0.4
UCEC	chr3	13375529	Missense_Mutation	rs762924843	T469M	0.53
UCEC	chr3	13319103	Silent	NA	T1844T	0.13
UCEC	chr3	13386294	Silent	novel	I266I	0.28
UCEC	chr3	13339966	Missense_Mutation	rs761847699	A1120V	0.5
UCEC	chr3	13319264	Silent	rs200679598	F1815F	0.47
UCEC	chr3	13353619	Missense_Mutation	novel	A855T	0.24
UCEC	chr3	13343223	Silent	novel	V972V	0.46
UCEC	chr3	13335595	Silent	novel	P1234P	0.28
UCEC	chr3	13317340	3'UTR	novel		0.52
UCEC	chr3	13317776	Missense_Mutation	rs766905662	A1857T	0.53
UCEC	chr3	13339965	Silent	rs113775377	A1120A	0.43
UCEC	chr3	13317136	3'UTR	novel		0.38
UCEC	chr3	13323326	Missense_Mutation	novel	R1584I	0.43
UCEC	chr3	13341776	Missense_Mutation	novel	R1067I	0.22
UCEC	chr3	13360380	Missense_Mutation	rs149471357	V682I	0.3
UCEC	chr3	13339902	Silent	rs140367875	L1141L	0.36
UCEC	chr3	13337911	Missense_Mutation	novel	V1160L	0.5
UCEC	chr3	13317343	3'UTR	novel		0.35
UCEC	chr3	13339938	Missense_Mutation	novel	Q1129H	0.34
UCEC	chr3	13391295	Missense_Mutation	novel	S150N	0.32
UCEC	chr3	13379647	Missense_Mutation	NA	R298W	0.14
UCEC	chr3	13373730	Silent	rs202170701	F525F	0.14
UCEC	chr3	13378927	Missense_Mutation	novel	E344K	0.29
UCEC	chr3	13325837	Silent	rs552467572	T1534T	0.44
UCEC	chr3	13342089	Missense_Mutation	rs146112308	R1000H	0.42
UCEC	chr3	13373802	Silent	NA	G501G	0.21
UCEC	chr3	13397415	Silent	rs745492911	R126R	0.45
UCEC	chr3	13352185	Splice_Site	novel	X877_splice	0.43
UCEC	chr3	13343198	Silent	novel	L981L	0.37
UCEC	chr3	13354060	Silent	rs746455791	Y792Y	0.38
UCEC	chr3	13375576	Silent	rs182823509	P453P	0.46
UCEC	chr3	13323357	Missense_Mutation	novel	A1574T	0.29
UCEC	chr3	13336883	Missense_Mutation	novel	Q1196H	0.43
UCEC	chr3	13376347	Missense_Mutation	novel	A413T	0.41
UCEC	chr3	13377497	Missense_Mutation	rs528786448	E371K	0.49
UCEC	chr3	13321703	Missense_Mutation	novel	A1683G	0.35
UCEC	chr3	13339965	Silent	rs113775377	A1120A	0.5
UCEC	chr3	13376424	Missense_Mutation	rs141201901	R387Q	0.13
UCEC	chr3	13319103	Silent	NA	T1844T	0.22
UCEC	chr3	13353554	Splice_Region	rs759373440	P876P	0.35
UCEC	chr3	13397360	Missense_Mutation	NA	E145K	0.35
UCEC	chr3	13358317	Missense_Mutation	rs373501669	V745I	0.1
UCEC	chr3	13351884	Missense_Mutation	rs433032	A944T	0.28
UCEC	chr3	13343224	Missense_Mutation	novel	V972A	0.29
UCEC	chr3	13321655	Missense_Mutation	novel	L1699P	0.07
UCEC	chr3	13377538	Missense_Mutation	novel	R357K	0.24
UCEC	chr3	13321680	Missense_Mutation	NA	L1691I	0.45
UCEC	chr3	13354012	Silent	novel	Q808Q	0.41
UCEC	chr3	13336797	Missense_Mutation	rs376583097	R1225Q	0.46
UCEC	chr3	13375595	Missense_Mutation	NA	E447G	0.35
UCEC	chr3	13352162	Missense_Mutation	rs749910933	S884L	0.27
UCEC	chr3	13360418	Missense_Mutation	novel	R669K	0.43
UCEC	chr3	13379674	Missense_Mutation	novel	I289V	0.27
UCEC	chr3	13335472	Silent	NA	S1275S	0.39
UCEC	chr3	13342087	Missense_Mutation	rs757686840	V1001M	0.17
UCEC	chr3	13353554	Splice_Region	rs759373440	P876P	0.27
UCEC	chr3	13323409	Silent	novel	R1556R	0.52
UCEC	chr3	13377554	Missense_Mutation	novel	V352F	0.53
UCEC	chr3	13319263	Missense_Mutation	rs375414642	A1816T	0.46
UCEC	chr3	13322258	Missense_Mutation	rs779161656	P1617L	0.44
UCEC	chr3	13328909	Missense_Mutation	novel	P1383L	0.31
UCEC	chr3	13330542	Missense_Mutation	novel	G1343E	0.07
UCS	chr3	13358255	Missense_Mutation	rs756021923	M765I	0.22
UCS	chr3	13378966	Missense_Mutation	novel	G331C	0.37
UVM	chr3	13328829	Missense_Mutation	rs769147767	D1410N	0.9

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.75	0.02241
COAD	DEL	0.1264	0.010931
KIRC	DEL	0.8447	2.8873e-53
LUAD	DEL	0.312	0.068154
SKCM	DEL	0.1608	0.13887
TGCT	DEL	0.2067	0.08422
THYM	DEL	0.0894	0.037527

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0043	Kaplan-Meier Survival Analysis
KIRC	0.0007	Kaplan-Meier Survival Analysis
SARC	0.029	Kaplan-Meier Survival Analysis
MESO	0.00016	Kaplan-Meier Survival Analysis
ACC	0.025	Kaplan-Meier Survival Analysis
UCS	0.037	Kaplan-Meier Survival Analysis
HNSC	0.018	Kaplan-Meier Survival Analysis
SKCM	0.048	Kaplan-Meier Survival Analysis
KIRP	0.00025	Kaplan-Meier Survival Analysis
PAAD	0.031	Kaplan-Meier Survival Analysis
PCPG	0.031	Kaplan-Meier Survival Analysis
BLCA	0.018	Kaplan-Meier Survival Analysis
LAML	0.00011	Kaplan-Meier Survival Analysis
UCEC	0.028	Kaplan-Meier Survival Analysis
LIHC	0.00077	Kaplan-Meier Survival Analysis
LGG	0.0017	Kaplan-Meier Survival Analysis
THCA	0.011	Kaplan-Meier Survival Analysis
OV	0.022	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742