EuRBPDB

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  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000132300 (Gene tree)
Gene ID
55037
Gene Symbol
PTCD3
Alias
FLJ20758|DKFZp666K071
Full Name
pentatricopeptide repeat domain 3
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
35,976 bases
Position
chr2:86,106,182-86,142,157
Accession
24717
RBP type
non-canonical RBP
Summary
(Pentatricopeptide Repeat Domain 3) is a Protein Coding gene. Diseases associated with PTCD3 include Mitochondrial Metabolism Disease. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include ribosomal small subunit binding.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
30132530Elevated expression of PTCD3 correlates with tumor progression and predicts poor prognosis in patients with prostate cancer.Mol Med Rep2018 OctHuang Ydoi: 10.3892/mmr.2018.9402
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000473829PTCD3-210587--- (aa)--
ENST00000483925PTCD3-214576--- (aa)--
ENST00000487043PTCD3-2161054--- (aa)--
ENST00000488801PTCD3-217568--- (aa)--
ENST00000409326PTCD3-202522-ENSP0000038696378 (aa)-F8WBP9
ENST00000409783PTCD3-203587-ENSP00000386922187 (aa)-B8ZZQ4
ENST00000467273PTCD3-207757--- (aa)--
ENST00000476215PTCD3-211754--- (aa)--
ENST00000480102PTCD3-213589--- (aa)--
ENST00000465560PTCD3-206747--- (aa)--
ENST00000493430PTCD3-218782--- (aa)--
ENST00000464541PTCD3-205890--- (aa)--
ENST00000472044PTCD3-209293--- (aa)--
ENST00000418628PTCD3-204532-ENSP0000039444169 (aa)-F8WE76
ENST00000469585PTCD3-208885--- (aa)--
ENST00000477520PTCD3-212556--- (aa)--
ENST00000494323PTCD3-219540--- (aa)--
ENST00000484203PTCD3-215928--- (aa)--
ENST00000254630PTCD3-2016734-ENSP00000254630689 (aa)-Q96EY7
ENST00000627371PTCD3-220210-ENSP0000048713569 (aa)-F8WE76
Gene Model
Click here to download ENSG00000132300's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000132300Breast Neoplasms1.5950000E-00417529973
ENSG00000132300Breast Neoplasms1.5870000E-00417529973
ENSG00000132300Breast Neoplasms2.0880000E-00417529973
ENSG00000132300Methylphenidate3E-621130132
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000132300rs2241437286133450CResponse to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure)21130132GO_0036271
ENSG00000132300rs10184246286114205?Lung function (FEV1/FVC)30595370EFO_0004713
ENSG00000132300rs3731818286141681GDiastolic blood pressure27841878unit increase0.117EFO_0006336
ENSG00000132300rs3731818286141681GSystolic blood pressure27841878unit increase0.24EFO_0006335
ENSG00000132300rs3731818286141681GPulse pressure27841878unit increase0.127EFO_0005763
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000132300's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000132300PTCD39151.905ENSDARG00000103856ptcd39352.251Danio_rerio
ENSG00000132300PTCD39330.441FBgn0033816CG46799730.475Drosophila_melanogaster
ENSG00000132300PTCD39674.063ENSMUSG00000063884Ptcd39773.997Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding24965446.IPIFunction
GO:0005654nucleoplasm-IDAComponent
GO:0005739mitochondrion19427859.IDAComponent
GO:0005743mitochondrial inner membrane-TASComponent
GO:0005829cytosol-IDAComponent
GO:0005840ribosome-IEAComponent
GO:0005886plasma membrane-IDAComponent
GO:0006417regulation of translation-IEAProcess
GO:0019843rRNA binding19427859.IDAFunction
GO:0032543mitochondrial translation19427859.IMPProcess
GO:0043024ribosomal small subunit binding19427859.IDAFunction
GO:0070125mitochondrial translational elongation-TASProcess
GO:0070126mitochondrial translational termination-TASProcess

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