EuRBPDB

Description

Ensembl ID: ENSG00000132305 (Gene tree)
Gene ID: 10989
Gene Symbol: IMMT
Alias: P87|P89|HMP|MINOS2|Mic60|MICOS60
Full Name: inner membrane mitochondrial protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 51,839 bases
Position: chr2:86,143,932-86,195,770
Accession: 6047
RBP type: non-canonical RBP
Summary: (Inner Membrane Mitochondrial Protein) is a Protein Coding gene. Diseases associated with IMMT include Melanoma-Associated Retinopathy and Gracile Syndrome.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15303970	Characterization of Staufen 1 ribonucleoprotein complexes.	Biochem J	2004 Dec 1	Brendel C	-
16352523	Characterization of an RNA granule from developing brain.	Mol Cell Proteomics	2006 Apr	Elvira G	-
28566250	Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation.	EBioMedicine	2017 Jun	Kobayashi S	doi: 10.1016/j.ebiom.2017.05.012
25612828	Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation.	Sci Rep	2015 Jan 23	Yang RF	doi: 10.1038/srep07990.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000409258	IMMT-203	1408	-	ENSP00000387237	147 (aa)	-	D6RAW4
ENST00000460081	IMMT-208	424	-	-	- (aa)	-	-
ENST00000409051	IMMT-202	2515	-	ENSP00000387227	711 (aa)	-	B9A067
ENST00000419070	IMMT-205	2172	XM_011532497	ENSP00000415762	613 (aa)	XP_011530799	H7C463
ENST00000474969	IMMT-209	1431	-	-	- (aa)	-	-
ENST00000442664	IMMT-206	2627	XM_005264113	ENSP00000407788	757 (aa)	XP_005264170	Q16891
ENST00000449247	IMMT-207	2670	XM_005264110	ENSP00000396899	747 (aa)	XP_005264167	Q16891
ENST00000410111	IMMT-204	3001	XM_017003194	ENSP00000387262	758 (aa)	XP_016858683	Q16891
ENST00000486633	IMMT-210	631	-	-	- (aa)	-	-
ENST00000490238	IMMT-211	699	-	-	- (aa)	-	-
ENST00000254636	IMMT-201	2613	-	ENSP00000254636	659 (aa)	-	C9J406
ENST00000620815	IMMT-212	1520	-	ENSP00000482042	372 (aa)	-	A0A087WYS0

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000132305	IMMT	100	97.241	ENSMUSG00000052337	Immt	100	92.407	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16169070.21081504.21900206.22228767.25764979.26168012.26666268.29128334.30021884.	IPI	Function
GO:0005739	mitochondrion	20833797.	HDA	Component
GO:0005739	mitochondrion	25781180.25997101.	IDA	Component
GO:0005743	mitochondrial inner membrane	9168817.25997101.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0042407	cristae formation	25781180.	IMP	Process
GO:0051560	mitochondrial calcium ion homeostasis	-	IEA	Process
GO:0061617	MICOS complex	25781180.25997101.	IDA	Component