EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000132664 (Gene tree)
Gene ID: 10621
Gene Symbol: POLR3F
Alias: RPC39|RPC6
Full Name: RNA polymerase III subunit F
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 17,522 bases
Position: chr20:18,467,127-18,484,648
Accession: 15763
RBP type: canonical RBP
Summary: The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000366828	RNA_pol_Rpc34	PF05158.12	2.8e-105	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
9171375	Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.	Genes Dev	1997 May 15	Wang Z	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000377603	POLR3F-201	2416	XM_011529141	ENSP00000366828	316 (aa)	XP_011527443	Q9H1D9
ENST00000461589	POLR3F-202	605	-	-	- (aa)	-	-
ENST00000497333	POLR3F-206	696	-	-	- (aa)	-	-
ENST00000475192	POLR3F-204	426	-	-	- (aa)	-	-
ENST00000489753	POLR3F-205	705	-	-	- (aa)	-	-
ENST00000462997	POLR3F-203	2257	NR_104209	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000132664's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG
hsa04623	Cytosolic DNA-sensing pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000132664's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000132664	POLR3F	100	85.759	ENSAPOG00000008271	polr3f	100	85.759	Acanthochromis_polyacanthus
ENSG00000132664	POLR3F	100	99.684	ENSAMEG00000005222	POLR3F	100	99.684	Ailuropoda_melanoleuca
ENSG00000132664	POLR3F	100	80.696	ENSACIG00000006705	polr3f	100	80.696	Amphilophus_citrinellus
ENSG00000132664	POLR3F	100	86.392	ENSAOCG00000000687	polr3f	100	86.392	Amphiprion_ocellaris
ENSG00000132664	POLR3F	100	86.076	ENSAPEG00000015263	polr3f	100	86.076	Amphiprion_percula
ENSG00000132664	POLR3F	87	89.455	ENSATEG00000015539	polr3f	100	89.455	Anabas_testudineus
ENSG00000132664	POLR3F	87	95.273	ENSAPLG00000005533	POLR3F	100	95.273	Anas_platyrhynchos
ENSG00000132664	POLR3F	96	93.069	ENSACAG00000014293	POLR3F	98	93.069	Anolis_carolinensis
ENSG00000132664	POLR3F	100	99.684	ENSANAG00000026726	POLR3F	100	99.684	Aotus_nancymaae
ENSG00000132664	POLR3F	100	87.025	ENSACLG00000003615	polr3f	100	87.025	Astatotilapia_calliptera
ENSG00000132664	POLR3F	100	87.658	ENSAMXG00000036020	polr3f	100	87.658	Astyanax_mexicanus
ENSG00000132664	POLR3F	100	99.367	ENSBTAG00000008825	POLR3F	100	99.367	Bos_taurus
ENSG00000132664	POLR3F	94	33.779	WBGene00021112	W09C3.4	95	33.779	Caenorhabditis_elegans
ENSG00000132664	POLR3F	100	99.684	ENSCJAG00000005159	POLR3F	100	99.684	Callithrix_jacchus
ENSG00000132664	POLR3F	100	99.367	ENSCAFG00000005420	POLR3F	100	99.367	Canis_familiaris
ENSG00000132664	POLR3F	100	99.367	ENSCAFG00020027500	POLR3F	100	99.367	Canis_lupus_dingo
ENSG00000132664	POLR3F	100	99.367	ENSCHIG00000014743	POLR3F	100	99.367	Capra_hircus
ENSG00000132664	POLR3F	100	99.051	ENSTSYG00000004207	POLR3F	100	99.051	Carlito_syrichta
ENSG00000132664	POLR3F	93	55.743	ENSCAPG00000008423	POLR3F	100	55.743	Cavia_aperea
ENSG00000132664	POLR3F	100	98.418	ENSCPOG00000002400	POLR3F	100	98.418	Cavia_porcellus
ENSG00000132664	POLR3F	100	88.608	ENSCCAG00000021800	POLR3F	100	88.608	Cebus_capucinus
ENSG00000132664	POLR3F	100	99.684	ENSCATG00000019507	POLR3F	100	99.684	Cercocebus_atys
ENSG00000132664	POLR3F	100	99.051	ENSCLAG00000016296	POLR3F	100	99.051	Chinchilla_lanigera
ENSG00000132664	POLR3F	100	99.684	ENSCSAG00000011513	POLR3F	100	99.684	Chlorocebus_sabaeus
ENSG00000132664	POLR3F	73	98.876	ENSCHOG00000013268	POLR3F	73	98.876	Choloepus_hoffmanni
ENSG00000132664	POLR3F	87	94.545	ENSCPBG00000023473	POLR3F	100	94.545	Chrysemys_picta_bellii
ENSG00000132664	POLR3F	99	60.952	ENSCING00000001212	-	99	60.952	Ciona_intestinalis
ENSG00000132664	POLR3F	70	59.193	ENSCSAVG00000003340	-	96	66.272	Ciona_savignyi
ENSG00000132664	POLR3F	92	99.656	ENSCANG00000037390	POLR3F	100	99.656	Colobus_angolensis_palliatus
ENSG00000132664	POLR3F	100	98.734	ENSCGRG00001002032	Polr3f	100	98.734	Cricetulus_griseus_chok1gshd
ENSG00000132664	POLR3F	100	98.734	ENSCGRG00000010852	Polr3f	100	98.734	Cricetulus_griseus_crigri
ENSG00000132664	POLR3F	100	84.810	ENSCSEG00000001247	polr3f	100	84.810	Cynoglossus_semilaevis
ENSG00000132664	POLR3F	100	85.759	ENSCVAG00000007611	polr3f	100	85.759	Cyprinodon_variegatus
ENSG00000132664	POLR3F	100	88.608	ENSDARG00000012572	polr3f	100	88.608	Danio_rerio
ENSG00000132664	POLR3F	100	96.519	ENSDNOG00000010719	POLR3F	100	96.519	Dasypus_novemcinctus
ENSG00000132664	POLR3F	100	99.367	ENSDORG00000016352	Polr3f	100	99.367	Dipodomys_ordii
ENSG00000132664	POLR3F	95	49.667	FBgn0038951	CG5380	99	49.667	Drosophila_melanogaster
ENSG00000132664	POLR3F	89	60.854	ENSETEG00000015485	-	100	60.854	Echinops_telfairi
ENSG00000132664	POLR3F	96	77.228	ENSEBUG00000006783	polr3f	97	77.228	Eptatretus_burgeri
ENSG00000132664	POLR3F	100	100.000	ENSEASG00005002022	POLR3F	100	100.000	Equus_asinus_asinus
ENSG00000132664	POLR3F	100	100.000	ENSECAG00000009920	POLR3F	100	100.000	Equus_caballus
ENSG00000132664	POLR3F	80	92.000	ENSEEUG00000000184	POLR3F	80	92.000	Erinaceus_europaeus
ENSG00000132664	POLR3F	100	89.241	ENSELUG00000001558	polr3f	100	89.241	Esox_lucius
ENSG00000132664	POLR3F	100	99.684	ENSFCAG00000013828	POLR3F	100	99.684	Felis_catus
ENSG00000132664	POLR3F	87	95.636	ENSFALG00000007623	POLR3F	100	95.636	Ficedula_albicollis
ENSG00000132664	POLR3F	100	98.734	ENSFDAG00000002528	POLR3F	100	98.734	Fukomys_damarensis
ENSG00000132664	POLR3F	100	83.228	ENSFHEG00000006450	polr3f	100	83.228	Fundulus_heteroclitus
ENSG00000132664	POLR3F	100	93.987	ENSGALG00000008749	POLR3F	100	93.987	Gallus_gallus
ENSG00000132664	POLR3F	100	84.810	ENSGAFG00000003698	polr3f	100	84.810	Gambusia_affinis
ENSG00000132664	POLR3F	100	93.354	ENSGAGG00000006151	POLR3F	100	93.354	Gopherus_agassizii
ENSG00000132664	POLR3F	100	100.000	ENSGGOG00000011543	POLR3F	100	100.000	Gorilla_gorilla
ENSG00000132664	POLR3F	100	87.342	ENSHBUG00000013806	polr3f	100	87.342	Haplochromis_burtoni
ENSG00000132664	POLR3F	100	98.418	ENSHGLG00000011867	POLR3F	100	98.418	Heterocephalus_glaber_female
ENSG00000132664	POLR3F	100	98.418	ENSHGLG00100012577	POLR3F	100	98.418	Heterocephalus_glaber_male
ENSG00000132664	POLR3F	100	76.899	ENSHCOG00000011751	polr3f	100	76.899	Hippocampus_comes
ENSG00000132664	POLR3F	98	87.781	ENSIPUG00000013347	polr3f	99	87.781	Ictalurus_punctatus
ENSG00000132664	POLR3F	100	99.684	ENSSTOG00000013588	POLR3F	100	99.684	Ictidomys_tridecemlineatus
ENSG00000132664	POLR3F	100	99.051	ENSJJAG00000017513	Polr3f	100	99.051	Jaculus_jaculus
ENSG00000132664	POLR3F	87	81.818	ENSKMAG00000016495	polr3f	100	81.818	Kryptolebias_marmoratus
ENSG00000132664	POLR3F	73	92.241	ENSLBEG00000011998	polr3f	100	92.241	Labrus_bergylta
ENSG00000132664	POLR3F	100	89.873	ENSLACG00000009371	POLR3F	100	89.873	Latimeria_chalumnae
ENSG00000132664	POLR3F	100	90.190	ENSLOCG00000015701	polr3f	100	90.190	Lepisosteus_oculatus
ENSG00000132664	POLR3F	100	99.051	ENSLAFG00000004929	POLR3F	100	99.051	Loxodonta_africana
ENSG00000132664	POLR3F	100	99.684	ENSMFAG00000002227	POLR3F	100	99.684	Macaca_fascicularis
ENSG00000132664	POLR3F	87	99.636	ENSMMUG00000004143	POLR3F	100	99.636	Macaca_mulatta
ENSG00000132664	POLR3F	100	99.684	ENSMNEG00000033404	POLR3F	100	99.684	Macaca_nemestrina
ENSG00000132664	POLR3F	100	99.684	ENSMLEG00000021905	POLR3F	100	99.684	Mandrillus_leucophaeus
ENSG00000132664	POLR3F	100	86.392	ENSMAMG00000017975	polr3f	100	86.392	Mastacembelus_armatus
ENSG00000132664	POLR3F	100	87.342	ENSMZEG00005015134	polr3f	100	87.342	Maylandia_zebra
ENSG00000132664	POLR3F	100	93.671	ENSMGAG00000006691	POLR3F	100	93.671	Meleagris_gallopavo
ENSG00000132664	POLR3F	100	99.051	ENSMAUG00000020176	Polr3f	100	99.051	Mesocricetus_auratus
ENSG00000132664	POLR3F	100	99.684	ENSMICG00000044519	POLR3F	100	99.684	Microcebus_murinus
ENSG00000132664	POLR3F	100	98.734	ENSMOCG00000018352	Polr3f	100	98.734	Microtus_ochrogaster
ENSG00000132664	POLR3F	93	88.215	ENSMMOG00000018477	polr3f	100	88.215	Mola_mola
ENSG00000132664	POLR3F	100	98.101	ENSMODG00000005624	POLR3F	100	98.101	Monodelphis_domestica
ENSG00000132664	POLR3F	100	87.342	ENSMALG00000006685	polr3f	100	87.342	Monopterus_albus
ENSG00000132664	POLR3F	100	98.734	MGP_CAROLIEiJ_G0024385	Polr3f	100	98.734	Mus_caroli
ENSG00000132664	POLR3F	100	98.734	ENSMUSG00000027427	Polr3f	100	98.734	Mus_musculus
ENSG00000132664	POLR3F	100	98.734	MGP_PahariEiJ_G0025829	Polr3f	100	98.734	Mus_pahari
ENSG00000132664	POLR3F	100	98.734	MGP_SPRETEiJ_G0025304	Polr3f	100	98.734	Mus_spretus
ENSG00000132664	POLR3F	100	77.538	ENSMPUG00000001252	-	100	77.538	Mustela_putorius_furo
ENSG00000132664	POLR3F	100	99.367	ENSMLUG00000014844	POLR3F	100	99.367	Myotis_lucifugus
ENSG00000132664	POLR3F	100	98.418	ENSNGAG00000010898	Polr3f	100	98.418	Nannospalax_galili
ENSG00000132664	POLR3F	100	87.658	ENSNBRG00000020796	polr3f	100	87.658	Neolamprologus_brichardi
ENSG00000132664	POLR3F	100	100.000	ENSNLEG00000009778	POLR3F	100	100.000	Nomascus_leucogenys
ENSG00000132664	POLR3F	93	91.864	ENSMEUG00000010320	POLR3F	100	91.864	Notamacropus_eugenii
ENSG00000132664	POLR3F	100	96.835	ENSOPRG00000003385	POLR3F	100	96.835	Ochotona_princeps
ENSG00000132664	POLR3F	100	98.734	ENSODEG00000011521	POLR3F	100	98.734	Octodon_degus
ENSG00000132664	POLR3F	100	86.076	ENSONIG00000006858	polr3f	100	86.076	Oreochromis_niloticus
ENSG00000132664	POLR3F	100	96.835	ENSOANG00000001253	POLR3F	100	96.835	Ornithorhynchus_anatinus
ENSG00000132664	POLR3F	100	99.367	ENSOCUG00000015067	POLR3F	100	99.367	Oryctolagus_cuniculus
ENSG00000132664	POLR3F	100	85.127	ENSORLG00000022412	polr3f	100	85.127	Oryzias_latipes
ENSG00000132664	POLR3F	100	85.127	ENSORLG00020021944	polr3f	100	85.127	Oryzias_latipes_hni
ENSG00000132664	POLR3F	100	98.101	ENSOGAG00000002916	POLR3F	100	98.101	Otolemur_garnettii
ENSG00000132664	POLR3F	100	62.975	ENSOARG00000008647	-	100	62.975	Ovis_aries
ENSG00000132664	POLR3F	100	99.367	ENSOARG00000000315	-	100	99.367	Ovis_aries
ENSG00000132664	POLR3F	100	100.000	ENSPPAG00000036681	POLR3F	100	100.000	Pan_paniscus
ENSG00000132664	POLR3F	100	99.684	ENSPPRG00000024604	POLR3F	100	99.684	Panthera_pardus
ENSG00000132664	POLR3F	100	99.684	ENSPTIG00000020292	POLR3F	100	99.684	Panthera_tigris_altaica
ENSG00000132664	POLR3F	100	100.000	ENSPTRG00000013287	POLR3F	100	100.000	Pan_troglodytes
ENSG00000132664	POLR3F	100	99.684	ENSPANG00000025015	POLR3F	100	99.684	Papio_anubis
ENSG00000132664	POLR3F	100	88.291	ENSPKIG00000004427	polr3f	100	88.291	Paramormyrops_kingsleyae
ENSG00000132664	POLR3F	87	95.636	ENSPSIG00000016613	POLR3F	100	95.636	Pelodiscus_sinensis
ENSG00000132664	POLR3F	100	54.545	ENSPMGG00000018350	polr3f	100	56.646	Periophthalmus_magnuspinnatus
ENSG00000132664	POLR3F	100	99.051	ENSPEMG00000006966	Polr3f	100	99.051	Peromyscus_maniculatus_bairdii
ENSG00000132664	POLR3F	100	80.063	ENSPMAG00000005530	polr3f	100	80.063	Petromyzon_marinus
ENSG00000132664	POLR3F	100	98.418	ENSPCIG00000000908	POLR3F	85	98.418	Phascolarctos_cinereus
ENSG00000132664	POLR3F	100	84.810	ENSPFOG00000018334	polr3f	100	84.810	Poecilia_formosa
ENSG00000132664	POLR3F	100	84.810	ENSPLAG00000021803	polr3f	100	84.810	Poecilia_latipinna
ENSG00000132664	POLR3F	100	84.810	ENSPMEG00000013150	polr3f	100	84.810	Poecilia_mexicana
ENSG00000132664	POLR3F	100	84.810	ENSPREG00000005278	polr3f	100	84.810	Poecilia_reticulata
ENSG00000132664	POLR3F	100	100.000	ENSPPYG00000010737	POLR3F	100	100.000	Pongo_abelii
ENSG00000132664	POLR3F	66	98.649	ENSPCAG00000004893	POLR3F	71	98.649	Procavia_capensis
ENSG00000132664	POLR3F	100	99.684	ENSPCOG00000004543	POLR3F	100	99.684	Propithecus_coquereli
ENSG00000132664	POLR3F	100	99.367	ENSPVAG00000000403	POLR3F	100	99.367	Pteropus_vampyrus
ENSG00000132664	POLR3F	100	87.342	ENSPNYG00000016276	polr3f	100	87.342	Pundamilia_nyererei
ENSG00000132664	POLR3F	100	88.291	ENSPNAG00000005164	polr3f	100	88.291	Pygocentrus_nattereri
ENSG00000132664	POLR3F	100	99.051	ENSRNOG00000007548	Polr3f	85	99.051	Rattus_norvegicus
ENSG00000132664	POLR3F	100	99.684	ENSRBIG00000021268	POLR3F	100	99.684	Rhinopithecus_bieti
ENSG00000132664	POLR3F	100	99.684	ENSRROG00000039911	POLR3F	100	99.684	Rhinopithecus_roxellana
ENSG00000132664	POLR3F	100	99.684	ENSSBOG00000018207	POLR3F	100	99.684	Saimiri_boliviensis_boliviensis
ENSG00000132664	POLR3F	100	77.603	ENSSHAG00000018160	POLR3F	100	76.656	Sarcophilus_harrisii
ENSG00000132664	POLR3F	100	89.557	ENSSFOG00015022433	polr3f	100	89.557	Scleropages_formosus
ENSG00000132664	POLR3F	100	85.759	ENSSMAG00000021029	polr3f	100	85.759	Scophthalmus_maximus
ENSG00000132664	POLR3F	100	77.215	ENSSDUG00000022435	polr3f	100	77.215	Seriola_dumerili
ENSG00000132664	POLR3F	100	87.025	ENSSLDG00000012761	polr3f	100	87.025	Seriola_lalandi_dorsalis
ENSG00000132664	POLR3F	100	89.557	ENSSARG00000006039	POLR3F	100	89.557	Sorex_araneus
ENSG00000132664	POLR3F	100	93.987	ENSSPUG00000001873	POLR3F	100	93.987	Sphenodon_punctatus
ENSG00000132664	POLR3F	100	78.797	ENSSPAG00000002092	polr3f	100	78.797	Stegastes_partitus
ENSG00000132664	POLR3F	100	99.051	ENSSSCG00000007095	POLR3F	100	99.051	Sus_scrofa
ENSG00000132664	POLR3F	100	93.354	ENSTGUG00000005839	POLR3F	100	93.354	Taeniopygia_guttata
ENSG00000132664	POLR3F	100	85.127	ENSTRUG00000012101	polr3f	100	85.127	Takifugu_rubripes
ENSG00000132664	POLR3F	100	83.861	ENSTNIG00000006456	polr3f	100	83.861	Tetraodon_nigroviridis
ENSG00000132664	POLR3F	100	82.911	ENSTBEG00000007921	POLR3F	100	82.911	Tupaia_belangeri
ENSG00000132664	POLR3F	100	99.367	ENSTTRG00000002580	POLR3F	100	99.367	Tursiops_truncatus
ENSG00000132664	POLR3F	53	98.795	ENSUAMG00000024166	POLR3F	100	98.795	Ursus_americanus
ENSG00000132664	POLR3F	100	99.367	ENSUMAG00000024944	POLR3F	100	99.367	Ursus_maritimus
ENSG00000132664	POLR3F	100	98.734	ENSVPAG00000009063	POLR3F	100	98.734	Vicugna_pacos
ENSG00000132664	POLR3F	100	99.367	ENSVVUG00000012925	POLR3F	100	99.367	Vulpes_vulpes
ENSG00000132664	POLR3F	100	89.241	ENSXETG00000024898	polr3f	100	89.241	Xenopus_tropicalis
ENSG00000132664	POLR3F	87	87.273	ENSXCOG00000010301	polr3f	100	87.273	Xiphophorus_couchianus
ENSG00000132664	POLR3F	100	85.127	ENSXMAG00000004604	polr3f	100	85.127	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001056	RNA polymerase III activity	21873635.	IBA	Function
GO:0003690	double-stranded DNA binding	21358628.	IDA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	9171375.	NAS	Function
GO:0005515	protein binding	16169070.17612402.18377933.20154270.21358628.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005666	RNA polymerase III complex	21873635.	IBA	Component
GO:0005666	RNA polymerase III complex	24107381.	IDA	Component
GO:0005666	RNA polymerase III complex	10623476.	NAS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006359	regulation of transcription by RNA polymerase III	9171375.	NAS	Process
GO:0006383	transcription by RNA polymerase III	-	IEA	Process
GO:0032481	positive regulation of type I interferon production	-	TAS	Process
GO:0032728	positive regulation of interferon-beta production	19631370.	IMP	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0045089	positive regulation of innate immune response	19631370.	IMP	Process
GO:0051607	defense response to virus	-	IEA	Process