EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000133858 (Gene tree)
Gene ID: 196441
Gene Symbol: ZFC3H1
Alias: MGC23401|KIAA0546|CSRC2|PSRC2|CCDC131
Full Name: zinc finger C3H1-type containing
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 58,254 bases
Position: chr12:71,609,472-71,667,725
Accession: 28328
RBP type: canonical RBP
Summary: (Zinc Finger C3H1-Type Containing) is a Protein Coding gene.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000368017	zf-C3H1	PF10650.9	8.9e-08	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000552037	ZFC3H1-211	1484	-	ENSP00000447976	358 (aa)	-	G3V1X1
ENST00000551487	ZFC3H1-210	746	-	-	- (aa)	-	-
ENST00000549407	ZFC3H1-207	852	-	-	- (aa)	-	-
ENST00000546771	ZFC3H1-204	381	-	-	- (aa)	-	-
ENST00000546475	ZFC3H1-202	550	-	-	- (aa)	-	-
ENST00000550712	ZFC3H1-208	571	-	-	- (aa)	-	-
ENST00000550963	ZFC3H1-209	845	-	-	- (aa)	-	-
ENST00000546606	ZFC3H1-203	498	-	-	- (aa)	-	-
ENST00000547398	ZFC3H1-205	470	-	-	- (aa)	-	-
ENST00000548100	ZFC3H1-206	1771	-	ENSP00000450044	346 (aa)	-	O60293
ENST00000552994	ZFC3H1-212	7597	-	ENSP00000446995	1910 (aa)	-	O60293
ENST00000378743	ZFC3H1-201	7285	-	ENSP00000368017	1989 (aa)	-	O60293

Gene Model

Click here to download ENSG00000133858's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000133858	Arteries	8.4630000E-005	-
ENSG00000133858	Lipoprotein(a)	8.9860000E-005	-
ENSG00000133858	Lipoprotein(a)	8.7050000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000133858	rs139369546	12	71632593	?	General cognitive ability	29844566	z-score decrease	4.587	EFO_0004337

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000133858's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000133858	ZFC3H1	100	96.032	ENSAMEG00000000498	ZFC3H1	100	96.032	Ailuropoda_melanoleuca
ENSG00000133858	ZFC3H1	95	53.465	ENSACIG00000015672	ZFC3H1	95	53.465	Amphilophus_citrinellus
ENSG00000133858	ZFC3H1	94	48.886	ENSAOCG00000022567	ZFC3H1	96	48.992	Amphiprion_ocellaris
ENSG00000133858	ZFC3H1	96	49.291	ENSATEG00000015391	ZFC3H1	96	49.501	Anabas_testudineus
ENSG00000133858	ZFC3H1	90	73.081	ENSAPLG00000016116	ZFC3H1	100	72.914	Anas_platyrhynchos
ENSG00000133858	ZFC3H1	99	68.300	ENSACAG00000007327	ZFC3H1	99	68.042	Anolis_carolinensis
ENSG00000133858	ZFC3H1	100	98.039	ENSANAG00000038329	ZFC3H1	100	98.039	Aotus_nancymaae
ENSG00000133858	ZFC3H1	84	49.356	ENSACLG00000021274	ZFC3H1	97	48.793	Astatotilapia_calliptera
ENSG00000133858	ZFC3H1	95	45.382	ENSAMXG00000042831	-	96	46.324	Astyanax_mexicanus
ENSG00000133858	ZFC3H1	100	94.520	ENSBTAG00000012267	ZFC3H1	100	95.123	Bos_taurus
ENSG00000133858	ZFC3H1	100	98.039	ENSCJAG00000001384	ZFC3H1	100	98.039	Callithrix_jacchus
ENSG00000133858	ZFC3H1	96	94.953	ENSCAFG00000000453	ZFC3H1	100	93.644	Canis_familiaris
ENSG00000133858	ZFC3H1	96	94.953	ENSCAFG00020016502	ZFC3H1	100	93.694	Canis_lupus_dingo
ENSG00000133858	ZFC3H1	100	95.224	ENSCHIG00000020097	ZFC3H1	100	95.224	Capra_hircus
ENSG00000133858	ZFC3H1	100	95.080	ENSTSYG00000005471	ZFC3H1	100	95.080	Carlito_syrichta
ENSG00000133858	ZFC3H1	98	94.118	ENSCPOG00000009504	ZFC3H1	100	91.005	Cavia_porcellus
ENSG00000133858	ZFC3H1	100	98.039	ENSCCAG00000035967	ZFC3H1	100	98.039	Cebus_capucinus
ENSG00000133858	ZFC3H1	100	99.296	ENSCATG00000016321	ZFC3H1	100	99.296	Cercocebus_atys
ENSG00000133858	ZFC3H1	100	94.676	ENSCLAG00000007646	ZFC3H1	100	94.676	Chinchilla_lanigera
ENSG00000133858	ZFC3H1	100	99.095	ENSCSAG00000004100	ZFC3H1	100	99.095	Chlorocebus_sabaeus
ENSG00000133858	ZFC3H1	99	74.837	ENSCPBG00000013449	ZFC3H1	94	75.794	Chrysemys_picta_bellii
ENSG00000133858	ZFC3H1	100	99.196	ENSCANG00000030229	ZFC3H1	100	99.196	Colobus_angolensis_palliatus
ENSG00000133858	ZFC3H1	100	89.123	ENSCGRG00001011660	Zfc3h1	100	89.073	Cricetulus_griseus_chok1gshd
ENSG00000133858	ZFC3H1	90	92.789	ENSCGRG00000006894	Zfc3h1	100	92.789	Cricetulus_griseus_crigri
ENSG00000133858	ZFC3H1	96	40.542	ENSCSEG00000021462	ZFC3H1	99	40.755	Cynoglossus_semilaevis
ENSG00000133858	ZFC3H1	99	48.794	ENSCVAG00000019629	-	99	48.826	Cyprinodon_variegatus
ENSG00000133858	ZFC3H1	100	94.671	ENSDNOG00000010314	ZFC3H1	100	94.570	Dasypus_novemcinctus
ENSG00000133858	ZFC3H1	84	40.867	ENSEBUG00000003491	-	61	40.614	Eptatretus_burgeri
ENSG00000133858	ZFC3H1	99	93.428	ENSEASG00005008229	ZFC3H1	100	94.319	Equus_asinus_asinus
ENSG00000133858	ZFC3H1	99	93.579	ENSECAG00000026833	ZFC3H1	100	94.470	Equus_caballus
ENSG00000133858	ZFC3H1	97	51.471	ENSELUG00000013421	-	94	51.524	Esox_lucius
ENSG00000133858	ZFC3H1	100	95.978	ENSFCAG00000024198	ZFC3H1	100	95.978	Felis_catus
ENSG00000133858	ZFC3H1	99	71.850	ENSFALG00000010320	ZFC3H1	99	72.150	Ficedula_albicollis
ENSG00000133858	ZFC3H1	100	94.322	ENSFDAG00000017503	ZFC3H1	100	94.322	Fukomys_damarensis
ENSG00000133858	ZFC3H1	92	49.680	ENSGMOG00000004527	-	89	49.462	Gadus_morhua
ENSG00000133858	ZFC3H1	99	71.644	ENSGALG00000010177	ZFC3H1	99	72.311	Gallus_gallus
ENSG00000133858	ZFC3H1	68	47.701	ENSGAFG00000013283	-	99	47.788	Gambusia_affinis
ENSG00000133858	ZFC3H1	99	46.425	ENSGACG00000007651	ZFC3H1	67	49.512	Gasterosteus_aculeatus
ENSG00000133858	ZFC3H1	99	74.372	ENSGAGG00000013798	ZFC3H1	100	75.436	Gopherus_agassizii
ENSG00000133858	ZFC3H1	100	99.648	ENSGGOG00000025994	ZFC3H1	100	99.648	Gorilla_gorilla
ENSG00000133858	ZFC3H1	100	94.425	ENSHGLG00000014297	ZFC3H1	100	94.425	Heterocephalus_glaber_female
ENSG00000133858	ZFC3H1	100	94.274	ENSHGLG00100006263	ZFC3H1	100	94.274	Heterocephalus_glaber_male
ENSG00000133858	ZFC3H1	87	34.036	ENSHCOG00000009144	-	70	49.254	Hippocampus_comes
ENSG00000133858	ZFC3H1	100	95.827	ENSSTOG00000002650	ZFC3H1	100	95.827	Ictidomys_tridecemlineatus
ENSG00000133858	ZFC3H1	83	48.571	ENSLBEG00000012352	-	87	54.701	Labrus_bergylta
ENSG00000133858	ZFC3H1	95	62.520	ENSLACG00000002585	ZFC3H1	99	61.519	Latimeria_chalumnae
ENSG00000133858	ZFC3H1	99	56.867	ENSLOCG00000016238	ZFC3H1	100	55.385	Lepisosteus_oculatus
ENSG00000133858	ZFC3H1	99	94.917	ENSLAFG00000005820	ZFC3H1	100	94.917	Loxodonta_africana
ENSG00000133858	ZFC3H1	100	99.296	ENSMFAG00000039403	ZFC3H1	100	99.296	Macaca_fascicularis
ENSG00000133858	ZFC3H1	100	99.296	ENSMMUG00000020943	ZFC3H1	100	99.296	Macaca_mulatta
ENSG00000133858	ZFC3H1	100	99.246	ENSMNEG00000008807	ZFC3H1	100	99.246	Macaca_nemestrina
ENSG00000133858	ZFC3H1	100	99.296	ENSMLEG00000029967	ZFC3H1	100	99.296	Mandrillus_leucophaeus
ENSG00000133858	ZFC3H1	99	50.858	ENSMAMG00000021320	ZFC3H1	93	51.200	Mastacembelus_armatus
ENSG00000133858	ZFC3H1	90	74.263	ENSMGAG00000010716	ZFC3H1	99	74.208	Meleagris_gallopavo
ENSG00000133858	ZFC3H1	100	96.179	ENSMICG00000009137	ZFC3H1	100	96.179	Microcebus_murinus
ENSG00000133858	ZFC3H1	99	82.236	ENSMODG00000020408	ZFC3H1	100	82.572	Monodelphis_domestica
ENSG00000133858	ZFC3H1	99	89.439	MGP_CAROLIEiJ_G0015814	Zfc3h1	99	90.250	Mus_caroli
ENSG00000133858	ZFC3H1	99	90.658	ENSMUSG00000034163	Zfc3h1	99	91.215	Mus_musculus
ENSG00000133858	ZFC3H1	100	88.837	MGP_PahariEiJ_G0031273	Zfc3h1	99	89.721	Mus_pahari
ENSG00000133858	ZFC3H1	99	90.768	MGP_SPRETEiJ_G0016636	Zfc3h1	99	91.324	Mus_spretus
ENSG00000133858	ZFC3H1	100	95.626	ENSMPUG00000017488	ZFC3H1	100	95.475	Mustela_putorius_furo
ENSG00000133858	ZFC3H1	100	92.103	ENSMLUG00000011723	ZFC3H1	99	92.195	Myotis_lucifugus
ENSG00000133858	ZFC3H1	100	92.060	ENSNGAG00000017623	Zfc3h1	100	92.060	Nannospalax_galili
ENSG00000133858	ZFC3H1	100	98.894	ENSNLEG00000004372	ZFC3H1	100	98.894	Nomascus_leucogenys
ENSG00000133858	ZFC3H1	78	96.429	ENSOPRG00000008075	ZFC3H1	79	94.286	Ochotona_princeps
ENSG00000133858	ZFC3H1	55	47.207	ENSONIG00000018271	ZFC3H1	99	47.765	Oreochromis_niloticus
ENSG00000133858	ZFC3H1	100	94.369	ENSOCUG00000004591	ZFC3H1	100	95.023	Oryctolagus_cuniculus
ENSG00000133858	ZFC3H1	95	46.159	ENSORLG00000000155	-	97	47.359	Oryzias_latipes
ENSG00000133858	ZFC3H1	95	46.159	ENSORLG00015020699	-	97	47.359	Oryzias_latipes_hsok
ENSG00000133858	ZFC3H1	95	47.280	ENSOMEG00000015403	-	87	47.970	Oryzias_melastigma
ENSG00000133858	ZFC3H1	100	95.329	ENSOGAG00000033606	ZFC3H1	100	95.329	Otolemur_garnettii
ENSG00000133858	ZFC3H1	100	94.369	ENSOARG00000014589	ZFC3H1	100	95.073	Ovis_aries
ENSG00000133858	ZFC3H1	100	99.799	ENSPPAG00000029409	ZFC3H1	100	99.799	Pan_paniscus
ENSG00000133858	ZFC3H1	100	95.928	ENSPPRG00000010196	ZFC3H1	100	95.928	Panthera_pardus
ENSG00000133858	ZFC3H1	100	95.928	ENSPTIG00000006898	ZFC3H1	100	95.928	Panthera_tigris_altaica
ENSG00000133858	ZFC3H1	100	99.849	ENSPTRG00000005224	ZFC3H1	100	99.849	Pan_troglodytes
ENSG00000133858	ZFC3H1	98	99.705	ENSPANG00000009558	ZFC3H1	100	96.581	Papio_anubis
ENSG00000133858	ZFC3H1	99	50.930	ENSPKIG00000023219	ZFC3H1	99	50.197	Paramormyrops_kingsleyae
ENSG00000133858	ZFC3H1	99	74.912	ENSPSIG00000012997	ZFC3H1	100	78.611	Pelodiscus_sinensis
ENSG00000133858	ZFC3H1	94	45.785	ENSPMGG00000007504	ZFC3H1	92	47.773	Periophthalmus_magnuspinnatus
ENSG00000133858	ZFC3H1	99	81.850	ENSPCIG00000025066	ZFC3H1	100	82.786	Phascolarctos_cinereus
ENSG00000133858	ZFC3H1	99	46.606	ENSPFOG00000001903	-	96	47.593	Poecilia_formosa
ENSG00000133858	ZFC3H1	87	48.348	ENSPLAG00000015995	-	95	49.288	Poecilia_latipinna
ENSG00000133858	ZFC3H1	95	46.897	ENSPMEG00000007517	-	96	46.252	Poecilia_mexicana
ENSG00000133858	ZFC3H1	100	99.598	ENSPPYG00000004773	ZFC3H1	100	99.598	Pongo_abelii
ENSG00000133858	ZFC3H1	98	93.491	ENSPCAG00000003723	ZFC3H1	90	88.962	Procavia_capensis
ENSG00000133858	ZFC3H1	100	96.229	ENSPCOG00000019879	ZFC3H1	100	96.229	Propithecus_coquereli
ENSG00000133858	ZFC3H1	98	95.280	ENSPVAG00000012354	ZFC3H1	96	91.382	Pteropus_vampyrus
ENSG00000133858	ZFC3H1	84	49.133	ENSPNYG00000005977	ZFC3H1	97	48.834	Pundamilia_nyererei
ENSG00000133858	ZFC3H1	69	48.913	ENSPNAG00000017704	-	70	48.571	Pygocentrus_nattereri
ENSG00000133858	ZFC3H1	98	87.826	ENSRNOG00000053060	Zfc3h1	100	84.387	Rattus_norvegicus
ENSG00000133858	ZFC3H1	98	99.705	ENSRBIG00000028462	ZFC3H1	100	96.129	Rhinopithecus_bieti
ENSG00000133858	ZFC3H1	100	99.196	ENSRROG00000040039	ZFC3H1	100	99.196	Rhinopithecus_roxellana
ENSG00000133858	ZFC3H1	100	96.833	ENSSBOG00000032676	ZFC3H1	100	96.833	Saimiri_boliviensis_boliviensis
ENSG00000133858	ZFC3H1	100	80.461	ENSSHAG00000002431	ZFC3H1	99	80.411	Sarcophilus_harrisii
ENSG00000133858	ZFC3H1	92	51.153	ENSSFOG00015018112	ZFC3H1	96	52.328	Scleropages_formosus
ENSG00000133858	ZFC3H1	95	48.705	ENSSMAG00000019783	ZFC3H1	98	48.758	Scophthalmus_maximus
ENSG00000133858	ZFC3H1	99	49.453	ENSSDUG00000000244	ZFC3H1	96	50.371	Seriola_dumerili
ENSG00000133858	ZFC3H1	91	50.000	ENSSLDG00000018408	ZFC3H1	96	50.081	Seriola_lalandi_dorsalis
ENSG00000133858	ZFC3H1	83	94.989	ENSSARG00000008639	ZFC3H1	88	92.627	Sorex_araneus
ENSG00000133858	ZFC3H1	86	48.933	ENSSPAG00000001916	-	92	49.353	Stegastes_partitus
ENSG00000133858	ZFC3H1	100	95.676	ENSSSCG00000000509	ZFC3H1	100	96.634	Sus_scrofa
ENSG00000133858	ZFC3H1	99	71.880	ENSTGUG00000007206	ZFC3H1	99	71.699	Taeniopygia_guttata
ENSG00000133858	ZFC3H1	62	47.868	ENSTRUG00000004528	-	89	47.949	Takifugu_rubripes
ENSG00000133858	ZFC3H1	86	98.529	ENSTBEG00000016441	ZFC3H1	84	98.529	Tupaia_belangeri
ENSG00000133858	ZFC3H1	98	95.575	ENSTTRG00000007328	ZFC3H1	100	93.514	Tursiops_truncatus
ENSG00000133858	ZFC3H1	100	96.078	ENSUAMG00000001880	ZFC3H1	100	96.078	Ursus_americanus
ENSG00000133858	ZFC3H1	100	95.224	ENSUMAG00000021131	ZFC3H1	99	95.224	Ursus_maritimus
ENSG00000133858	ZFC3H1	90	95.980	ENSVVUG00000008655	ZFC3H1	99	95.980	Vulpes_vulpes
ENSG00000133858	ZFC3H1	95	58.408	ENSXETG00000033302	ZFC3H1	99	59.067	Xenopus_tropicalis
ENSG00000133858	ZFC3H1	99	47.909	ENSXMAG00000006933	-	98	47.842	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000178	exosome (RNase complex)	27871484.	IDA	Component
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	20195357.27871484.	IPI	Function
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005634	nucleus	27871484.	IDA	Component
GO:0005730	nucleolus	27871484.	IDA	Component
GO:0006396	RNA processing	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function