EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000134186 (Gene tree)
Gene ID: 55119
Gene Symbol: PRPF38B
Alias: FLJ10330|NET1
Full Name: pre-mRNA processing factor 38B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 9,512 bases
Position: chr1:108,692,292-108,701,803
Accession: 25512
RBP type: canonical RBP
Summary: (Pre-MRNA Processing Factor 38B) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000359042	PRP38	PF03371.15	6.1e-57	1	1
ENSP00000359039	PRP38	PF03371.15	2.8e-47	1	1
ENSP00000359038	PRP38	PF03371.15	2.2e-35	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000370022	PRPF38B-202	1591	XM_011541687	ENSP00000359039	190 (aa)	XP_011539989	Q5VTL8
ENST00000370021	PRPF38B-201	3728	XM_017001597	ENSP00000359038	435 (aa)	XP_016857086	A0A0A0MRN0
ENST00000485810	PRPF38B-205	1352	-	-	- (aa)	-	-
ENST00000370025	PRPF38B-203	3693	-	ENSP00000359042	546 (aa)	-	Q5VTL8
ENST00000467302	PRPF38B-204	2043	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000134186's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000134186's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000134186	PRPF38B	100	100.000	ENSANAG00000028333	PRPF38B	100	100.000	Aotus_nancymaae
ENSG00000134186	PRPF38B	100	94.301	ENSCGRG00001018841	Prpf38b	100	92.532	Cricetulus_griseus_chok1gshd
ENSG00000134186	PRPF38B	97	91.924	ENSCGRG00000002972	Prpf38b	100	92.291	Cricetulus_griseus_crigri
ENSG00000134186	PRPF38B	100	94.713	ENSDORG00000025236	-	100	94.713	Dipodomys_ordii
ENSG00000134186	PRPF38B	76	90.972	ENSEBUG00000001683	-	58	73.134	Eptatretus_burgeri
ENSG00000134186	PRPF38B	100	95.288	ENSEEUG00000014328	PRPF38B	100	92.139	Erinaceus_europaeus
ENSG00000134186	PRPF38B	100	97.241	ENSFDAG00000021009	PRPF38B	100	96.337	Fukomys_damarensis
ENSG00000134186	PRPF38B	100	100.000	ENSGGOG00000011288	PRPF38B	100	100.000	Gorilla_gorilla
ENSG00000134186	PRPF38B	100	86.697	ENSMGAG00000006188	PRPF38B	100	89.157	Meleagris_gallopavo
ENSG00000134186	PRPF38B	100	96.335	ENSMAUG00000019131	Prpf38b	100	92.139	Mesocricetus_auratus
ENSG00000134186	PRPF38B	100	96.842	MGP_CAROLIEiJ_G0025542	Prpf38b	99	97.826	Mus_caroli
ENSG00000134186	PRPF38B	100	96.335	ENSMUSG00000027881	Prpf38b	99	96.774	Mus_musculus
ENSG00000134186	PRPF38B	100	96.335	MGP_PahariEiJ_G0026988	Prpf38b	99	96.774	Mus_pahari
ENSG00000134186	PRPF38B	100	96.335	MGP_SPRETEiJ_G0026492	Prpf38b	99	96.774	Mus_spretus
ENSG00000134186	PRPF38B	100	99.080	ENSNLEG00000001645	-	100	98.953	Nomascus_leucogenys
ENSG00000134186	PRPF38B	100	94.023	ENSNLEG00000030268	-	100	91.941	Nomascus_leucogenys
ENSG00000134186	PRPF38B	100	100.000	ENSPPAG00000001260	PRPF38B	100	100.000	Pan_paniscus
ENSG00000134186	PRPF38B	100	98.438	ENSPPRG00000002116	PRPF38B	100	98.438	Panthera_pardus
ENSG00000134186	PRPF38B	100	100.000	ENSPTRG00000001032	PRPF38B	100	100.000	Pan_troglodytes
ENSG00000134186	PRPF38B	100	99.080	ENSPANG00000007560	PRPF38B	100	98.953	Papio_anubis
ENSG00000134186	PRPF38B	100	94.845	ENSPCIG00000024841	PRPF38B	61	94.848	Phascolarctos_cinereus
ENSG00000134186	PRPF38B	100	97.445	ENSPVAG00000011929	-	100	97.445	Pteropus_vampyrus
ENSG00000134186	PRPF38B	100	97.241	ENSSARG00000012818	-	100	96.370	Sorex_araneus
ENSG00000134186	PRPF38B	98	87.302	ENSTGUG00000004594	-	71	89.329	Taeniopygia_guttata
ENSG00000134186	PRPF38B	100	98.394	ENSUAMG00000023817	PRPF38B	100	98.361	Ursus_americanus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0006397	mRNA processing	-	IEA	Process
GO:0008380	RNA splicing	-	IEA	Process
GO:0071011	precatalytic spliceosome	21873635.	IBA	Component