EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000134627 (Gene tree)
Gene ID: 143689
Gene Symbol: PIWIL4
Alias: FLJ36156|HIWI2|Miwi2
Full Name: piwi like RNA-mediated gene silencing 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 77,582 bases
Position: chr11:94,543,840-94,621,421
Accession: 18444
RBP type: canonical RBP
Summary: PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000299001	PAZ	PF02170.22	1.5e-30	1	1
ENSP00000299001	Piwi	PF02171.17	3.6e-88	1	1
ENSP00000439710	Piwi	PF02171.17	2.4e-56	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000537419	PIWIL4-203	831	-	ENSP00000439710	203 (aa)	-	F5H116
ENST00000543336	PIWIL4-204	1901	-	ENSP00000444575	453 (aa)	-	Q7Z3Z4
ENST00000446230	PIWIL4-202	3759	-	ENSP00000413838	495 (aa)	-	Q7Z3Z4
ENST00000545603	PIWIL4-205	587	-	ENSP00000440499	118 (aa)	-	F5GX26
ENST00000299001	PIWIL4-201	3199	-	ENSP00000299001	852 (aa)	-	Q7Z3Z4

Gene Model

Click here to download ENSG00000134627's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000134627	Alcoholism	8.05812e-005	22978509
ENSG00000134627	Fructose-Bisphosphate Aldolase	6.7720000E-005	-
ENSG00000134627	Attention Deficit Disorder with Hyperactivity	9E-7	18846501
ENSG00000134627	Prion Diseases	4E-6	25897833
ENSG00000134627	Mood Disorders	4E-6	25897833
ENSG00000134627	Prion Diseases	8E-6	25897833
ENSG00000134627	Mood Disorders	8E-6	25897833

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000134627	rs7942260	11	94612336	?	Colorectal cancer	29228715	[NR]	1.4398848	EFO_0005842
ENSG00000134627	rs12279741	11	94551363	G	Small cell lung carcinoma	28604730	[1.401328759-2.374685998]	1.8242028	EFO_0000702
ENSG00000134627	rs2212361	11	94579157	C	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	18846501	[NR] unit decrease	0.97	EFO_0003888\|EFO_0008342
ENSG00000134627	rs591584	11	94592673	G	Macrophage Migration Inhibitory Factor levels	27989323	[0.061-0.158] SD units increase	0.1096	EFO_0008221

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000134627's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000134627	PIWIL4	89	54.144	ENSG00000184571	PIWIL3	100	41.645
ENSG00000134627	PIWIL4	89	61.326	ENSG00000125207	PIWIL1	100	48.958
ENSG00000134627	PIWIL4	89	48.066	ENSG00000197181	PIWIL2	78	39.318

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000134627	PIWIL4	89	46.961	ENSAPOG00000020227	piwil2	83	36.399	Acanthochromis_polyacanthus
ENSG00000134627	PIWIL4	90	58.791	ENSAPOG00000004324	piwil1	100	48.070	Acanthochromis_polyacanthus
ENSG00000134627	PIWIL4	89	60.773	ENSAMEG00000006533	PIWIL1	100	48.608	Ailuropoda_melanoleuca
ENSG00000134627	PIWIL4	89	48.066	ENSAMEG00000003171	PIWIL2	78	38.976	Ailuropoda_melanoleuca
ENSG00000134627	PIWIL4	100	81.356	ENSAMEG00000007580	PIWIL4	100	80.886	Ailuropoda_melanoleuca
ENSG00000134627	PIWIL4	89	44.751	ENSAMEG00000008922	-	99	40.469	Ailuropoda_melanoleuca
ENSG00000134627	PIWIL4	89	47.778	ENSACIG00000018881	piwil2	95	46.953	Amphilophus_citrinellus
ENSG00000134627	PIWIL4	90	59.890	ENSAOCG00000012967	piwil1	100	48.028	Amphiprion_ocellaris
ENSG00000134627	PIWIL4	89	46.154	ENSAOCG00000009899	piwil2	99	37.746	Amphiprion_ocellaris
ENSG00000134627	PIWIL4	90	55.495	ENSAPEG00000009239	piwil1	100	46.729	Amphiprion_percula
ENSG00000134627	PIWIL4	89	46.111	ENSAPEG00000005521	piwil2	99	44.291	Amphiprion_percula
ENSG00000134627	PIWIL4	89	46.409	ENSATEG00000016118	piwil2	74	37.327	Anabas_testudineus
ENSG00000134627	PIWIL4	55	36.667	ENSATEG00000020984	-	86	41.553	Anabas_testudineus
ENSG00000134627	PIWIL4	50	54.000	ENSATEG00000021001	-	85	43.939	Anabas_testudineus
ENSG00000134627	PIWIL4	90	62.088	ENSATEG00000019796	piwil1	100	48.832	Anabas_testudineus
ENSG00000134627	PIWIL4	99	52.137	ENSAPLG00000012285	PIWIL1	100	48.744	Anas_platyrhynchos
ENSG00000134627	PIWIL4	90	43.407	ENSAPLG00000014006	PIWIL2	99	35.493	Anas_platyrhynchos
ENSG00000134627	PIWIL4	89	63.536	ENSACAG00000015614	-	100	49.141	Anolis_carolinensis
ENSG00000134627	PIWIL4	89	63.536	ENSACAG00000010879	-	94	51.131	Anolis_carolinensis
ENSG00000134627	PIWIL4	89	46.961	ENSACAG00000010657	PIWIL2	86	38.583	Anolis_carolinensis
ENSG00000134627	PIWIL4	100	92.274	ENSANAG00000031191	PIWIL4	100	91.859	Aotus_nancymaae
ENSG00000134627	PIWIL4	89	51.934	ENSANAG00000031385	PIWIL3	100	34.994	Aotus_nancymaae
ENSG00000134627	PIWIL4	99	52.991	ENSANAG00000024013	PIWIL1	100	49.017	Aotus_nancymaae
ENSG00000134627	PIWIL4	89	48.619	ENSANAG00000027198	PIWIL2	78	38.502	Aotus_nancymaae
ENSG00000134627	PIWIL4	99	57.005	ENSACLG00000005074	-	95	57.005	Astatotilapia_calliptera
ENSG00000134627	PIWIL4	94	58.115	ENSACLG00000014540	piwil1	100	47.740	Astatotilapia_calliptera
ENSG00000134627	PIWIL4	100	58.049	ENSACLG00000005069	-	100	56.585	Astatotilapia_calliptera
ENSG00000134627	PIWIL4	99	44.956	ENSACLG00000005760	-	96	45.433	Astatotilapia_calliptera
ENSG00000134627	PIWIL4	89	47.778	ENSACLG00000020551	piwil2	75	37.093	Astatotilapia_calliptera
ENSG00000134627	PIWIL4	89	59.116	ENSAMXG00000015370	piwil1	100	48.032	Astyanax_mexicanus
ENSG00000134627	PIWIL4	89	46.667	ENSAMXG00000001746	piwil2	69	37.008	Astyanax_mexicanus
ENSG00000134627	PIWIL4	89	48.619	ENSBTAG00000015835	PIWIL2	78	39.318	Bos_taurus
ENSG00000134627	PIWIL4	89	61.326	ENSBTAG00000006468	PIWIL1	100	48.608	Bos_taurus
ENSG00000134627	PIWIL4	99	87.179	ENSBTAG00000014910	PIWIL4	98	80.141	Bos_taurus
ENSG00000134627	PIWIL4	89	51.366	ENSBTAG00000015526	PIWIL3	100	38.591	Bos_taurus
ENSG00000134627	PIWIL4	89	44.560	WBGene00004178	prg-1	95	32.955	Caenorhabditis_elegans
ENSG00000134627	PIWIL4	89	48.619	ENSCJAG00000020263	PIWIL2	78	38.371	Callithrix_jacchus
ENSG00000134627	PIWIL4	100	94.068	ENSCJAG00000004075	PIWIL4	100	94.301	Callithrix_jacchus
ENSG00000134627	PIWIL4	99	52.137	ENSCJAG00000010879	PIWIL1	100	49.133	Callithrix_jacchus
ENSG00000134627	PIWIL4	89	53.297	ENSCAFG00000010566	PIWIL3	100	40.023	Canis_familiaris
ENSG00000134627	PIWIL4	99	51.429	ENSCAFG00000006773	PIWIL1	100	48.671	Canis_familiaris
ENSG00000134627	PIWIL4	89	48.619	ENSCAFG00000009444	PIWIL2	78	39.450	Canis_familiaris
ENSG00000134627	PIWIL4	98	81.862	ENSCAFG00000004147	PIWIL4	100	81.542	Canis_familiaris
ENSG00000134627	PIWIL4	99	85.644	ENSCAFG00020016521	PIWIL4	97	85.644	Canis_lupus_dingo
ENSG00000134627	PIWIL4	89	61.326	ENSCAFG00020011618	PIWIL1	100	47.851	Canis_lupus_dingo
ENSG00000134627	PIWIL4	89	54.396	ENSCAFG00020020864	PIWIL3	94	42.471	Canis_lupus_dingo
ENSG00000134627	PIWIL4	89	48.619	ENSCAFG00020012983	PIWIL2	78	39.450	Canis_lupus_dingo
ENSG00000134627	PIWIL4	89	50.273	ENSCHIG00000024941	-	89	38.926	Capra_hircus
ENSG00000134627	PIWIL4	99	86.325	ENSCHIG00000007777	PIWIL4	100	81.221	Capra_hircus
ENSG00000134627	PIWIL4	89	61.326	ENSCHIG00000008831	PIWIL1	100	48.608	Capra_hircus
ENSG00000134627	PIWIL4	89	48.619	ENSCHIG00000022958	PIWIL2	78	39.187	Capra_hircus
ENSG00000134627	PIWIL4	89	62.431	ENSTSYG00000006226	PIWIL1	100	49.250	Carlito_syrichta
ENSG00000134627	PIWIL4	89	49.171	ENSTSYG00000009617	PIWIL2	91	36.580	Carlito_syrichta
ENSG00000134627	PIWIL4	99	84.615	ENSTSYG00000005577	PIWIL4	99	81.746	Carlito_syrichta
ENSG00000134627	PIWIL4	89	61.878	ENSCAPG00000006492	PIWIL1	95	49.749	Cavia_aperea
ENSG00000134627	PIWIL4	70	86.620	ENSCAPG00000001129	-	95	81.013	Cavia_aperea
ENSG00000134627	PIWIL4	100	83.051	ENSCPOG00000000070	PIWIL4	99	79.057	Cavia_porcellus
ENSG00000134627	PIWIL4	89	61.878	ENSCPOG00000004830	PIWIL1	95	50.814	Cavia_porcellus
ENSG00000134627	PIWIL4	89	49.444	ENSCPOG00000001108	PIWIL2	78	39.239	Cavia_porcellus
ENSG00000134627	PIWIL4	89	50.829	ENSCPOG00000026791	-	96	36.399	Cavia_porcellus
ENSG00000134627	PIWIL4	100	93.377	ENSCCAG00000017581	PIWIL4	100	93.435	Cebus_capucinus
ENSG00000134627	PIWIL4	89	51.381	ENSCCAG00000025474	PIWIL3	100	37.853	Cebus_capucinus
ENSG00000134627	PIWIL4	89	48.619	ENSCCAG00000033068	PIWIL2	78	38.502	Cebus_capucinus
ENSG00000134627	PIWIL4	99	52.991	ENSCCAG00000036270	PIWIL1	100	49.249	Cebus_capucinus
ENSG00000134627	PIWIL4	89	61.326	ENSCATG00000033903	PIWIL1	100	48.724	Cercocebus_atys
ENSG00000134627	PIWIL4	89	53.039	ENSCATG00000044030	PIWIL3	98	39.130	Cercocebus_atys
ENSG00000134627	PIWIL4	89	48.066	ENSCATG00000039784	PIWIL2	78	38.845	Cercocebus_atys
ENSG00000134627	PIWIL4	100	98.305	ENSCATG00000030289	PIWIL4	100	98.005	Cercocebus_atys
ENSG00000134627	PIWIL4	89	50.000	ENSCLAG00000013810	PIWIL2	79	38.946	Chinchilla_lanigera
ENSG00000134627	PIWIL4	89	61.878	ENSCLAG00000008176	PIWIL1	95	50.879	Chinchilla_lanigera
ENSG00000134627	PIWIL4	89	84.530	ENSCLAG00000000369	-	100	82.495	Chinchilla_lanigera
ENSG00000134627	PIWIL4	100	97.458	ENSCSAG00000003360	PIWIL4	100	97.300	Chlorocebus_sabaeus
ENSG00000134627	PIWIL4	89	48.066	ENSCSAG00000016512	PIWIL2	78	38.976	Chlorocebus_sabaeus
ENSG00000134627	PIWIL4	89	53.591	ENSCSAG00000010421	PIWIL3	100	39.359	Chlorocebus_sabaeus
ENSG00000134627	PIWIL4	89	61.326	ENSCSAG00000001922	PIWIL1	100	48.786	Chlorocebus_sabaeus
ENSG00000134627	PIWIL4	89	85.083	ENSCHOG00000008023	PIWIL4	79	84.731	Choloepus_hoffmanni
ENSG00000134627	PIWIL4	85	48.256	ENSCHOG00000003987	PIWIL2	65	39.806	Choloepus_hoffmanni
ENSG00000134627	PIWIL4	89	61.326	ENSCHOG00000012232	PIWIL1	100	47.503	Choloepus_hoffmanni
ENSG00000134627	PIWIL4	100	67.550	ENSCPBG00000024031	PIWIL4	99	69.520	Chrysemys_picta_bellii
ENSG00000134627	PIWIL4	89	61.326	ENSCPBG00000024818	PIWIL1	100	49.591	Chrysemys_picta_bellii
ENSG00000134627	PIWIL4	89	46.961	ENSCPBG00000001412	PIWIL2	99	34.881	Chrysemys_picta_bellii
ENSG00000134627	PIWIL4	89	49.189	ENSCING00000020739	-	88	40.320	Ciona_intestinalis
ENSG00000134627	PIWIL4	51	64.423	ENSCING00000009676	-	99	64.423	Ciona_intestinalis
ENSG00000134627	PIWIL4	67	38.636	ENSCING00000017557	-	99	38.770	Ciona_intestinalis
ENSG00000134627	PIWIL4	89	51.630	ENSCSAVG00000000100	-	94	41.522	Ciona_savignyi
ENSG00000134627	PIWIL4	89	54.645	ENSCSAVG00000003205	-	97	43.603	Ciona_savignyi
ENSG00000134627	PIWIL4	89	61.326	ENSCANG00000038755	PIWIL1	100	48.786	Colobus_angolensis_palliatus
ENSG00000134627	PIWIL4	92	36.111	ENSCANG00000039176	PIWIL3	100	33.074	Colobus_angolensis_palliatus
ENSG00000134627	PIWIL4	100	98.305	ENSCANG00000041660	PIWIL4	100	97.653	Colobus_angolensis_palliatus
ENSG00000134627	PIWIL4	89	48.066	ENSCANG00000003031	PIWIL2	78	38.845	Colobus_angolensis_palliatus
ENSG00000134627	PIWIL4	100	76.436	ENSCGRG00001017873	Piwil4	100	76.436	Cricetulus_griseus_chok1gshd
ENSG00000134627	PIWIL4	89	58.564	ENSCGRG00001016679	-	96	49.487	Cricetulus_griseus_chok1gshd
ENSG00000134627	PIWIL4	89	48.619	ENSCGRG00001013004	Piwil2	80	39.075	Cricetulus_griseus_chok1gshd
ENSG00000134627	PIWIL4	99	51.282	ENSCGRG00001023409	-	100	49.076	Cricetulus_griseus_chok1gshd
ENSG00000134627	PIWIL4	89	48.619	ENSCGRG00000005237	Piwil2	80	39.075	Cricetulus_griseus_crigri
ENSG00000134627	PIWIL4	99	51.282	ENSCGRG00000004482	-	100	49.076	Cricetulus_griseus_crigri
ENSG00000134627	PIWIL4	99	77.212	ENSCGRG00000016077	Piwil4	100	81.004	Cricetulus_griseus_crigri
ENSG00000134627	PIWIL4	89	58.564	ENSCGRG00000000724	-	100	49.708	Cricetulus_griseus_crigri
ENSG00000134627	PIWIL4	89	59.669	ENSCSEG00000015998	piwil1	100	46.929	Cynoglossus_semilaevis
ENSG00000134627	PIWIL4	89	45.304	ENSCSEG00000011256	piwil2	72	36.945	Cynoglossus_semilaevis
ENSG00000134627	PIWIL4	89	43.646	ENSCVAG00000022932	piwil2	76	36.282	Cyprinodon_variegatus
ENSG00000134627	PIWIL4	89	46.409	ENSDARG00000062601	piwil2	72	38.633	Danio_rerio
ENSG00000134627	PIWIL4	94	57.068	ENSDARG00000041699	piwil1	100	47.277	Danio_rerio
ENSG00000134627	PIWIL4	94	82.883	ENSDNOG00000016814	PIWIL4	100	78.093	Dasypus_novemcinctus
ENSG00000134627	PIWIL4	89	61.326	ENSDNOG00000015261	PIWIL1	94	50.522	Dasypus_novemcinctus
ENSG00000134627	PIWIL4	89	49.171	ENSDNOG00000001468	PIWIL2	85	37.786	Dasypus_novemcinctus
ENSG00000134627	PIWIL4	93	81.915	ENSDORG00000029165	-	100	80.319	Dipodomys_ordii
ENSG00000134627	PIWIL4	89	61.326	ENSDORG00000010479	Piwil1	100	48.789	Dipodomys_ordii
ENSG00000134627	PIWIL4	89	41.304	ENSDORG00000011177	Piwil2	78	34.018	Dipodomys_ordii
ENSG00000134627	PIWIL4	95	44.615	FBgn0004872	piwi	90	35.079	Drosophila_melanogaster
ENSG00000134627	PIWIL4	96	44.330	FBgn0250816	AGO3	86	36.196	Drosophila_melanogaster
ENSG00000134627	PIWIL4	92	44.503	FBgn0000146	aub	99	32.721	Drosophila_melanogaster
ENSG00000134627	PIWIL4	74	78.161	ENSETEG00000000516	-	69	87.179	Echinops_telfairi
ENSG00000134627	PIWIL4	89	61.878	ENSETEG00000001720	PIWIL1	100	48.789	Echinops_telfairi
ENSG00000134627	PIWIL4	89	39.227	ENSETEG00000004818	PIWIL2	78	32.546	Echinops_telfairi
ENSG00000134627	PIWIL4	69	42.466	ENSEBUG00000000869	-	80	43.056	Eptatretus_burgeri
ENSG00000134627	PIWIL4	89	60.221	ENSEBUG00000003745	piwil1	98	45.546	Eptatretus_burgeri
ENSG00000134627	PIWIL4	89	48.619	ENSEASG00005018819	PIWIL2	78	39.239	Equus_asinus_asinus
ENSG00000134627	PIWIL4	89	54.144	ENSEASG00005007918	PIWIL3	100	40.939	Equus_asinus_asinus
ENSG00000134627	PIWIL4	100	73.333	ENSEASG00005011309	-	100	73.333	Equus_asinus_asinus
ENSG00000134627	PIWIL4	87	62.500	ENSEASG00005013191	PIWIL1	100	48.383	Equus_asinus_asinus
ENSG00000134627	PIWIL4	89	61.878	ENSECAG00000016506	PIWIL1	83	48.671	Equus_caballus
ENSG00000134627	PIWIL4	100	85.593	ENSECAG00000024385	PIWIL4	100	83.920	Equus_caballus
ENSG00000134627	PIWIL4	89	54.144	ENSECAG00000018484	PIWIL3	100	41.309	Equus_caballus
ENSG00000134627	PIWIL4	89	48.619	ENSECAG00000025128	PIWIL2	78	39.239	Equus_caballus
ENSG00000134627	PIWIL4	89	61.326	ENSEEUG00000003872	PIWIL1	92	57.576	Erinaceus_europaeus
ENSG00000134627	PIWIL4	61	72.581	ENSEEUG00000004977	-	59	78.378	Erinaceus_europaeus
ENSG00000134627	PIWIL4	93	35.981	ENSEEUG00000005861	PIWIL2	76	37.500	Erinaceus_europaeus
ENSG00000134627	PIWIL4	99	47.863	ENSELUG00000019888	piwil1	100	47.796	Esox_lucius
ENSG00000134627	PIWIL4	89	47.778	ENSELUG00000007978	piwil2	71	39.136	Esox_lucius
ENSG00000134627	PIWIL4	99	51.282	ENSFCAG00000014305	PIWIL1	100	48.555	Felis_catus
ENSG00000134627	PIWIL4	89	48.901	ENSFCAG00000006400	PIWIL3	100	37.810	Felis_catus
ENSG00000134627	PIWIL4	89	48.619	ENSFCAG00000012981	PIWIL2	78	39.318	Felis_catus
ENSG00000134627	PIWIL4	99	83.186	ENSFCAG00000010914	PIWIL4	100	81.573	Felis_catus
ENSG00000134627	PIWIL4	89	60.000	ENSFALG00000009492	PIWIL1	100	52.282	Ficedula_albicollis
ENSG00000134627	PIWIL4	100	81.898	ENSFDAG00000017791	PIWIL4	100	81.659	Fukomys_damarensis
ENSG00000134627	PIWIL4	89	50.556	ENSFDAG00000007369	PIWIL2	78	39.712	Fukomys_damarensis
ENSG00000134627	PIWIL4	89	50.829	ENSFDAG00000020222	-	99	40.029	Fukomys_damarensis
ENSG00000134627	PIWIL4	99	52.137	ENSFDAG00000011345	PIWIL1	100	50.483	Fukomys_damarensis
ENSG00000134627	PIWIL4	90	58.791	ENSFHEG00000001418	piwil1	100	48.425	Fundulus_heteroclitus
ENSG00000134627	PIWIL4	89	47.222	ENSFHEG00000022000	piwil2	74	37.370	Fundulus_heteroclitus
ENSG00000134627	PIWIL4	89	47.541	ENSGMOG00000007585	piwil2	98	39.930	Gadus_morhua
ENSG00000134627	PIWIL4	89	59.116	ENSGMOG00000006726	piwil1	100	47.079	Gadus_morhua
ENSG00000134627	PIWIL4	89	60.000	ENSGALG00000002645	PIWIL1	100	47.991	Gallus_gallus
ENSG00000134627	PIWIL4	89	46.111	ENSGAFG00000006228	piwil2	72	37.008	Gambusia_affinis
ENSG00000134627	PIWIL4	85	61.272	ENSGAFG00000001781	-	93	61.494	Gambusia_affinis
ENSG00000134627	PIWIL4	64	48.000	ENSGAFG00000001753	-	98	51.082	Gambusia_affinis
ENSG00000134627	PIWIL4	89	47.514	ENSGACG00000012851	piwil2	98	39.405	Gasterosteus_aculeatus
ENSG00000134627	PIWIL4	89	62.431	ENSGACG00000012220	piwil1	100	47.907	Gasterosteus_aculeatus
ENSG00000134627	PIWIL4	100	66.949	ENSGAGG00000009717	PIWIL4	99	68.911	Gopherus_agassizii
ENSG00000134627	PIWIL4	89	61.878	ENSGAGG00000003090	PIWIL1	100	49.537	Gopherus_agassizii
ENSG00000134627	PIWIL4	89	45.856	ENSGAGG00000012123	PIWIL2	78	37.664	Gopherus_agassizii
ENSG00000134627	PIWIL4	90	47.802	ENSGGOG00000008783	-	91	39.474	Gorilla_gorilla
ENSG00000134627	PIWIL4	89	61.326	ENSGGOG00000015722	PIWIL1	100	48.958	Gorilla_gorilla
ENSG00000134627	PIWIL4	100	99.178	ENSGGOG00000016276	PIWIL4	100	99.178	Gorilla_gorilla
ENSG00000134627	PIWIL4	89	54.144	ENSGGOG00000015492	PIWIL3	100	41.645	Gorilla_gorilla
ENSG00000134627	PIWIL4	99	46.491	ENSHBUG00000000983	piwil1	98	46.602	Haplochromis_burtoni
ENSG00000134627	PIWIL4	95	44.560	ENSHBUG00000011225	piwil2	95	42.652	Haplochromis_burtoni
ENSG00000134627	PIWIL4	89	48.889	ENSHGLG00000015853	PIWIL2	78	38.845	Heterocephalus_glaber_female
ENSG00000134627	PIWIL4	99	52.991	ENSHGLG00000011158	PIWIL1	100	48.961	Heterocephalus_glaber_female
ENSG00000134627	PIWIL4	89	86.740	ENSHGLG00000007416	-	100	85.339	Heterocephalus_glaber_female
ENSG00000134627	PIWIL4	89	48.889	ENSHGLG00100019213	PIWIL2	78	38.845	Heterocephalus_glaber_male
ENSG00000134627	PIWIL4	89	86.740	ENSHGLG00100010413	-	100	85.339	Heterocephalus_glaber_male
ENSG00000134627	PIWIL4	99	52.991	ENSHGLG00100019433	PIWIL1	100	48.961	Heterocephalus_glaber_male
ENSG00000134627	PIWIL4	90	59.341	ENSHCOG00000000796	piwil1	99	48.116	Hippocampus_comes
ENSG00000134627	PIWIL4	89	47.222	ENSHCOG00000002903	piwil2	95	42.294	Hippocampus_comes
ENSG00000134627	PIWIL4	71	44.898	ENSIPUG00000012980	-	86	43.871	Ictalurus_punctatus
ENSG00000134627	PIWIL4	76	37.662	ENSIPUG00000007306	-	82	35.294	Ictalurus_punctatus
ENSG00000134627	PIWIL4	83	39.181	ENSIPUG00000007028	-	89	38.372	Ictalurus_punctatus
ENSG00000134627	PIWIL4	71	50.000	ENSIPUG00000011241	-	94	44.215	Ictalurus_punctatus
ENSG00000134627	PIWIL4	99	47.863	ENSIPUG00000016443	piwil1	100	46.145	Ictalurus_punctatus
ENSG00000134627	PIWIL4	89	47.222	ENSIPUG00000018436	piwil2	95	35.550	Ictalurus_punctatus
ENSG00000134627	PIWIL4	71	42.953	ENSIPUG00000005939	-	93	41.104	Ictalurus_punctatus
ENSG00000134627	PIWIL4	74	43.333	ENSIPUG00000020606	-	88	34.538	Ictalurus_punctatus
ENSG00000134627	PIWIL4	89	87.845	ENSSTOG00000006932	-	100	85.558	Ictidomys_tridecemlineatus
ENSG00000134627	PIWIL4	89	61.326	ENSSTOG00000005154	PIWIL1	100	48.555	Ictidomys_tridecemlineatus
ENSG00000134627	PIWIL4	89	48.619	ENSSTOG00000016520	PIWIL2	80	39.075	Ictidomys_tridecemlineatus
ENSG00000134627	PIWIL4	89	61.326	ENSJJAG00000022411	Piwil1	100	48.730	Jaculus_jaculus
ENSG00000134627	PIWIL4	89	48.066	ENSJJAG00000005065	Piwil2	90	33.800	Jaculus_jaculus
ENSG00000134627	PIWIL4	90	61.538	ENSKMAG00000020353	piwil1	100	48.260	Kryptolebias_marmoratus
ENSG00000134627	PIWIL4	89	48.066	ENSKMAG00000009865	piwil2	99	45.172	Kryptolebias_marmoratus
ENSG00000134627	PIWIL4	90	62.637	ENSLBEG00000024216	piwil1	100	46.963	Labrus_bergylta
ENSG00000134627	PIWIL4	89	46.667	ENSLBEG00000008001	piwil2	95	36.516	Labrus_bergylta
ENSG00000134627	PIWIL4	89	63.536	ENSLACG00000018850	PIWIL1	100	49.653	Latimeria_chalumnae
ENSG00000134627	PIWIL4	99	35.958	ENSLACG00000001069	PIWIL2	88	35.958	Latimeria_chalumnae
ENSG00000134627	PIWIL4	92	58.333	ENSLACG00000001172	PIWIL4	100	56.229	Latimeria_chalumnae
ENSG00000134627	PIWIL4	89	57.222	ENSLOCG00000006283	piwil1	100	47.174	Lepisosteus_oculatus
ENSG00000134627	PIWIL4	89	46.111	ENSLOCG00000015407	piwil2	71	38.765	Lepisosteus_oculatus
ENSG00000134627	PIWIL4	89	48.619	ENSLAFG00000016420	PIWIL2	78	38.714	Loxodonta_africana
ENSG00000134627	PIWIL4	89	61.326	ENSLAFG00000013812	PIWIL1	100	48.786	Loxodonta_africana
ENSG00000134627	PIWIL4	100	83.051	ENSLAFG00000008418	PIWIL4	100	81.272	Loxodonta_africana
ENSG00000134627	PIWIL4	89	61.326	ENSMFAG00000042638	PIWIL1	100	48.724	Macaca_fascicularis
ENSG00000134627	PIWIL4	100	98.305	ENSMFAG00000042631	PIWIL4	100	97.887	Macaca_fascicularis
ENSG00000134627	PIWIL4	89	48.066	ENSMFAG00000038537	PIWIL2	78	38.714	Macaca_fascicularis
ENSG00000134627	PIWIL4	89	53.591	ENSMFAG00000003570	PIWIL3	100	41.384	Macaca_fascicularis
ENSG00000134627	PIWIL4	100	98.305	ENSMMUG00000008965	PIWIL4	100	97.653	Macaca_mulatta
ENSG00000134627	PIWIL4	89	48.066	ENSMMUG00000014438	PIWIL2	78	38.714	Macaca_mulatta
ENSG00000134627	PIWIL4	89	53.591	ENSMMUG00000020325	PIWIL3	100	39.135	Macaca_mulatta
ENSG00000134627	PIWIL4	89	61.326	ENSMMUG00000005629	PIWIL1	100	47.326	Macaca_mulatta
ENSG00000134627	PIWIL4	89	61.326	ENSMNEG00000044909	PIWIL1	100	48.724	Macaca_nemestrina
ENSG00000134627	PIWIL4	89	53.591	ENSMNEG00000040579	PIWIL3	100	38.914	Macaca_nemestrina
ENSG00000134627	PIWIL4	100	98.305	ENSMNEG00000037456	PIWIL4	100	97.653	Macaca_nemestrina
ENSG00000134627	PIWIL4	89	48.066	ENSMNEG00000029268	PIWIL2	78	37.353	Macaca_nemestrina
ENSG00000134627	PIWIL4	89	61.326	ENSMLEG00000035718	PIWIL1	100	48.724	Mandrillus_leucophaeus
ENSG00000134627	PIWIL4	100	98.305	ENSMLEG00000029752	PIWIL4	100	97.535	Mandrillus_leucophaeus
ENSG00000134627	PIWIL4	89	54.144	ENSMLEG00000038128	PIWIL3	100	41.514	Mandrillus_leucophaeus
ENSG00000134627	PIWIL4	97	44.949	ENSMLEG00000041768	PIWIL2	77	36.794	Mandrillus_leucophaeus
ENSG00000134627	PIWIL4	89	47.778	ENSMAMG00000000487	piwil2	100	37.063	Mastacembelus_armatus
ENSG00000134627	PIWIL4	89	60.773	ENSMAMG00000005264	piwil1	100	47.319	Mastacembelus_armatus
ENSG00000134627	PIWIL4	100	55.981	ENSMZEG00005003521	-	100	55.981	Maylandia_zebra
ENSG00000134627	PIWIL4	99	56.650	ENSMZEG00005018090	-	95	56.373	Maylandia_zebra
ENSG00000134627	PIWIL4	89	47.778	ENSMZEG00005018757	piwil2	75	37.093	Maylandia_zebra
ENSG00000134627	PIWIL4	94	58.115	ENSMZEG00005008579	piwil1	100	46.821	Maylandia_zebra
ENSG00000134627	PIWIL4	89	58.889	ENSMGAG00000002382	PIWIL1	100	47.881	Meleagris_gallopavo
ENSG00000134627	PIWIL4	97	35.214	ENSMAUG00000003138	Piwil2	76	35.761	Mesocricetus_auratus
ENSG00000134627	PIWIL4	100	75.498	ENSMAUG00000011382	Piwil4	100	80.568	Mesocricetus_auratus
ENSG00000134627	PIWIL4	99	51.282	ENSMAUG00000016892	Piwil1	100	49.076	Mesocricetus_auratus
ENSG00000134627	PIWIL4	89	48.619	ENSMICG00000001062	PIWIL2	78	38.976	Microcebus_murinus
ENSG00000134627	PIWIL4	92	51.872	ENSMICG00000029782	PIWIL3	100	37.729	Microcebus_murinus
ENSG00000134627	PIWIL4	90	60.656	ENSMICG00000004852	PIWIL1	100	48.436	Microcebus_murinus
ENSG00000134627	PIWIL4	100	86.854	ENSMICG00000006375	PIWIL4	100	86.854	Microcebus_murinus
ENSG00000134627	PIWIL4	100	74.178	ENSMOCG00000020261	Piwil4	100	74.178	Microtus_ochrogaster
ENSG00000134627	PIWIL4	89	60.773	ENSMOCG00000015999	Piwil1	100	49.076	Microtus_ochrogaster
ENSG00000134627	PIWIL4	89	48.619	ENSMOCG00000003446	Piwil2	80	39.075	Microtus_ochrogaster
ENSG00000134627	PIWIL4	89	46.409	ENSMMOG00000014703	piwil2	92	36.877	Mola_mola
ENSG00000134627	PIWIL4	89	60.773	ENSMMOG00000001839	piwil1	99	47.649	Mola_mola
ENSG00000134627	PIWIL4	89	48.619	ENSMODG00000009482	PIWIL2	100	38.259	Monodelphis_domestica
ENSG00000134627	PIWIL4	100	70.396	ENSMODG00000000217	PIWIL4	100	70.396	Monodelphis_domestica
ENSG00000134627	PIWIL4	99	53.846	ENSMODG00000015619	PIWIL1	100	49.710	Monodelphis_domestica
ENSG00000134627	PIWIL4	90	46.154	ENSMALG00000017274	piwil2	74	36.616	Monopterus_albus
ENSG00000134627	PIWIL4	90	58.242	ENSMALG00000019391	piwil1	100	46.799	Monopterus_albus
ENSG00000134627	PIWIL4	100	78.814	MGP_CAROLIEiJ_G0031784	Piwil4	100	80.568	Mus_caroli
ENSG00000134627	PIWIL4	99	51.282	MGP_CAROLIEiJ_G0027775	Piwil1	100	49.076	Mus_caroli
ENSG00000134627	PIWIL4	89	48.619	MGP_CAROLIEiJ_G0019480	Piwil2	78	39.450	Mus_caroli
ENSG00000134627	PIWIL4	99	51.282	ENSMUSG00000029423	Piwil1	100	49.076	Mus_musculus
ENSG00000134627	PIWIL4	100	80.508	ENSMUSG00000036912	Piwil4	100	77.374	Mus_musculus
ENSG00000134627	PIWIL4	89	48.619	ENSMUSG00000033644	Piwil2	78	39.450	Mus_musculus
ENSG00000134627	PIWIL4	89	48.619	MGP_PahariEiJ_G0030497	Piwil2	78	39.450	Mus_pahari
ENSG00000134627	PIWIL4	100	77.966	MGP_PahariEiJ_G0014660	Piwil4	100	81.004	Mus_pahari
ENSG00000134627	PIWIL4	99	51.282	MGP_PahariEiJ_G0024355	Piwil1	100	49.192	Mus_pahari
ENSG00000134627	PIWIL4	99	51.282	MGP_SPRETEiJ_G0028774	Piwil1	100	49.076	Mus_spretus
ENSG00000134627	PIWIL4	100	79.661	MGP_SPRETEiJ_G0032904	Piwil4	100	80.131	Mus_spretus
ENSG00000134627	PIWIL4	89	48.619	MGP_SPRETEiJ_G0020372	Piwil2	78	39.450	Mus_spretus
ENSG00000134627	PIWIL4	89	61.326	ENSMPUG00000004243	PIWIL1	100	48.671	Mustela_putorius_furo
ENSG00000134627	PIWIL4	89	51.099	ENSMPUG00000013703	PIWIL3	100	37.415	Mustela_putorius_furo
ENSG00000134627	PIWIL4	99	80.931	ENSMPUG00000012256	PIWIL4	99	81.211	Mustela_putorius_furo
ENSG00000134627	PIWIL4	89	48.619	ENSMPUG00000003645	PIWIL2	78	39.450	Mustela_putorius_furo
ENSG00000134627	PIWIL4	100	83.223	ENSMLUG00000002018	PIWIL4	100	82.981	Myotis_lucifugus
ENSG00000134627	PIWIL4	89	48.619	ENSMLUG00000002115	PIWIL2	80	39.460	Myotis_lucifugus
ENSG00000134627	PIWIL4	99	52.137	ENSNGAG00000017950	Piwil1	100	49.421	Nannospalax_galili
ENSG00000134627	PIWIL4	100	79.912	ENSNGAG00000022297	Piwil4	100	79.132	Nannospalax_galili
ENSG00000134627	PIWIL4	89	48.619	ENSNGAG00000015408	Piwil2	78	39.581	Nannospalax_galili
ENSG00000134627	PIWIL4	94	58.639	ENSNBRG00000008895	piwil1	100	47.664	Neolamprologus_brichardi
ENSG00000134627	PIWIL4	89	40.884	ENSNBRG00000001164	-	94	39.614	Neolamprologus_brichardi
ENSG00000134627	PIWIL4	89	48.066	ENSNLEG00000015534	PIWIL2	79	36.435	Nomascus_leucogenys
ENSG00000134627	PIWIL4	89	61.326	ENSNLEG00000008225	PIWIL1	100	48.208	Nomascus_leucogenys
ENSG00000134627	PIWIL4	89	54.144	ENSNLEG00000007677	PIWIL3	100	38.713	Nomascus_leucogenys
ENSG00000134627	PIWIL4	100	99.153	ENSNLEG00000007119	PIWIL4	100	94.014	Nomascus_leucogenys
ENSG00000134627	PIWIL4	89	35.912	ENSMEUG00000016543	-	54	35.266	Notamacropus_eugenii
ENSG00000134627	PIWIL4	99	53.846	ENSMEUG00000010800	PIWIL1	92	49.091	Notamacropus_eugenii
ENSG00000134627	PIWIL4	89	77.901	ENSMEUG00000005110	PIWIL4	85	69.697	Notamacropus_eugenii
ENSG00000134627	PIWIL4	100	82.203	ENSOPRG00000004245	-	99	72.235	Ochotona_princeps
ENSG00000134627	PIWIL4	99	50.427	ENSOPRG00000003656	-	86	46.201	Ochotona_princeps
ENSG00000134627	PIWIL4	86	34.264	ENSOPRG00000013167	PIWIL2	69	35.612	Ochotona_princeps
ENSG00000134627	PIWIL4	63	54.331	ENSOPRG00000009976	-	50	54.839	Ochotona_princeps
ENSG00000134627	PIWIL4	100	81.356	ENSODEG00000013015	PIWIL4	100	77.700	Octodon_degus
ENSG00000134627	PIWIL4	89	62.431	ENSODEG00000010629	PIWIL1	100	46.296	Octodon_degus
ENSG00000134627	PIWIL4	89	50.000	ENSODEG00000009752	PIWIL2	78	39.108	Octodon_degus
ENSG00000134627	PIWIL4	94	58.115	ENSONIG00000010951	piwil1	100	48.204	Oreochromis_niloticus
ENSG00000134627	PIWIL4	89	47.778	ENSONIG00000011121	piwil2	74	37.374	Oreochromis_niloticus
ENSG00000134627	PIWIL4	89	62.983	ENSOANG00000011950	-	100	50.631	Ornithorhynchus_anatinus
ENSG00000134627	PIWIL4	89	48.066	ENSOANG00000010778	PIWIL2	78	40.473	Ornithorhynchus_anatinus
ENSG00000134627	PIWIL4	89	61.326	ENSOCUG00000027444	PIWIL1	100	49.076	Oryctolagus_cuniculus
ENSG00000134627	PIWIL4	89	48.619	ENSOCUG00000006261	PIWIL2	78	39.318	Oryctolagus_cuniculus
ENSG00000134627	PIWIL4	100	84.746	ENSOCUG00000002860	PIWIL4	99	82.222	Oryctolagus_cuniculus
ENSG00000134627	PIWIL4	89	52.486	ENSOCUG00000017781	PIWIL3	99	37.775	Oryctolagus_cuniculus
ENSG00000134627	PIWIL4	88	47.486	ENSORLG00000013656	piwil2	68	37.714	Oryzias_latipes
ENSG00000134627	PIWIL4	90	58.791	ENSORLG00000013695	piwil1	100	46.404	Oryzias_latipes
ENSG00000134627	PIWIL4	89	47.222	ENSORLG00020010494	piwil2	73	37.714	Oryzias_latipes_hni
ENSG00000134627	PIWIL4	90	58.791	ENSORLG00020002279	piwil1	100	46.404	Oryzias_latipes_hni
ENSG00000134627	PIWIL4	88	47.486	ENSORLG00015018666	piwil2	73	37.714	Oryzias_latipes_hsok
ENSG00000134627	PIWIL4	90	58.791	ENSORLG00015015958	piwil1	100	46.288	Oryzias_latipes_hsok
ENSG00000134627	PIWIL4	90	59.341	ENSOMEG00000015298	piwil1	100	46.217	Oryzias_melastigma
ENSG00000134627	PIWIL4	89	45.000	ENSOMEG00000018436	piwil2	76	37.582	Oryzias_melastigma
ENSG00000134627	PIWIL4	89	48.619	ENSOGAG00000004913	PIWIL2	78	38.976	Otolemur_garnettii
ENSG00000134627	PIWIL4	89	61.326	ENSOGAG00000015400	PIWIL1	100	48.499	Otolemur_garnettii
ENSG00000134627	PIWIL4	99	84.768	ENSOGAG00000012156	PIWIL4	100	84.750	Otolemur_garnettii
ENSG00000134627	PIWIL4	99	87.179	ENSOARG00000009613	PIWIL4	99	80.422	Ovis_aries
ENSG00000134627	PIWIL4	100	39.408	ENSOARG00000018486	PIWIL3	99	40.667	Ovis_aries
ENSG00000134627	PIWIL4	89	48.619	ENSOARG00000010357	PIWIL2	78	39.187	Ovis_aries
ENSG00000134627	PIWIL4	89	61.326	ENSOARG00000016263	PIWIL1	93	50.734	Ovis_aries
ENSG00000134627	PIWIL4	89	54.144	ENSPPAG00000031985	PIWIL3	100	38.939	Pan_paniscus
ENSG00000134627	PIWIL4	100	99.531	ENSPPAG00000031181	PIWIL4	100	99.531	Pan_paniscus
ENSG00000134627	PIWIL4	86	47.429	ENSPPAG00000033460	PIWIL2	78	38.693	Pan_paniscus
ENSG00000134627	PIWIL4	89	61.326	ENSPPAG00000018598	PIWIL1	100	48.904	Pan_paniscus
ENSG00000134627	PIWIL4	89	40.331	ENSPPRG00000000518	PIWIL2	77	37.484	Panthera_pardus
ENSG00000134627	PIWIL4	99	52.137	ENSPPRG00000001911	PIWIL1	100	48.786	Panthera_pardus
ENSG00000134627	PIWIL4	90	55.495	ENSPPRG00000011117	PIWIL3	100	42.802	Panthera_pardus
ENSG00000134627	PIWIL4	100	83.898	ENSPPRG00000007432	PIWIL4	100	82.512	Panthera_pardus
ENSG00000134627	PIWIL4	90	55.495	ENSPTIG00000009971	PIWIL3	100	42.672	Panthera_tigris_altaica
ENSG00000134627	PIWIL4	89	48.619	ENSPTIG00000019334	PIWIL2	78	39.318	Panthera_tigris_altaica
ENSG00000134627	PIWIL4	99	51.282	ENSPTIG00000005342	PIWIL1	100	48.671	Panthera_tigris_altaica
ENSG00000134627	PIWIL4	100	83.898	ENSPTIG00000020931	PIWIL4	99	83.293	Panthera_tigris_altaica
ENSG00000134627	PIWIL4	100	99.413	ENSPTRG00000004187	PIWIL4	100	99.413	Pan_troglodytes
ENSG00000134627	PIWIL4	89	54.144	ENSPTRG00000014180	PIWIL3	100	38.939	Pan_troglodytes
ENSG00000134627	PIWIL4	89	61.326	ENSPTRG00000005633	PIWIL1	100	48.904	Pan_troglodytes
ENSG00000134627	PIWIL4	89	48.066	ENSPTRG00000022613	PIWIL2	78	38.976	Pan_troglodytes
ENSG00000134627	PIWIL4	89	61.326	ENSPANG00000003836	PIWIL1	100	48.724	Papio_anubis
ENSG00000134627	PIWIL4	100	98.305	ENSPANG00000016066	PIWIL4	100	97.887	Papio_anubis
ENSG00000134627	PIWIL4	89	48.066	ENSPANG00000018061	PIWIL2	78	38.845	Papio_anubis
ENSG00000134627	PIWIL4	89	49.171	ENSPANG00000022557	PIWIL3	100	37.414	Papio_anubis
ENSG00000134627	PIWIL4	89	47.222	ENSPKIG00000025025	piwil2	78	39.028	Paramormyrops_kingsleyae
ENSG00000134627	PIWIL4	99	48.718	ENSPKIG00000008517	piwil1	100	47.552	Paramormyrops_kingsleyae
ENSG00000134627	PIWIL4	99	50.427	ENSPSIG00000011944	PIWIL1	98	47.084	Pelodiscus_sinensis
ENSG00000134627	PIWIL4	100	68.644	ENSPSIG00000014155	PIWIL4	100	66.822	Pelodiscus_sinensis
ENSG00000134627	PIWIL4	99	57.921	ENSPMGG00000009081	-	100	56.000	Periophthalmus_magnuspinnatus
ENSG00000134627	PIWIL4	99	47.009	ENSPMGG00000009085	piwil1	95	44.915	Periophthalmus_magnuspinnatus
ENSG00000134627	PIWIL4	89	45.856	ENSPMGG00000001380	-	93	45.421	Periophthalmus_magnuspinnatus
ENSG00000134627	PIWIL4	100	75.147	ENSPEMG00000023859	Piwil4	100	75.147	Peromyscus_maniculatus_bairdii
ENSG00000134627	PIWIL4	89	48.619	ENSPEMG00000021798	Piwil2	78	39.450	Peromyscus_maniculatus_bairdii
ENSG00000134627	PIWIL4	99	51.282	ENSPEMG00000019053	Piwil1	100	48.845	Peromyscus_maniculatus_bairdii
ENSG00000134627	PIWIL4	90	45.604	ENSPMAG00000001669	piwil2	99	39.258	Petromyzon_marinus
ENSG00000134627	PIWIL4	100	48.361	ENSPMAG00000009302	piwil1	100	44.835	Petromyzon_marinus
ENSG00000134627	PIWIL4	100	71.302	ENSPCIG00000030600	PIWIL4	100	71.278	Phascolarctos_cinereus
ENSG00000134627	PIWIL4	99	52.137	ENSPCIG00000021062	PIWIL1	100	51.264	Phascolarctos_cinereus
ENSG00000134627	PIWIL4	89	56.593	ENSPCIG00000021061	-	87	42.657	Phascolarctos_cinereus
ENSG00000134627	PIWIL4	89	48.333	ENSPCIG00000012698	PIWIL2	78	39.239	Phascolarctos_cinereus
ENSG00000134627	PIWIL4	89	46.409	ENSPFOG00000012110	piwil2	68	37.196	Poecilia_formosa
ENSG00000134627	PIWIL4	90	59.341	ENSPFOG00000016960	piwil1	100	47.045	Poecilia_formosa
ENSG00000134627	PIWIL4	89	46.667	ENSPLAG00000014526	piwil2	72	37.139	Poecilia_latipinna
ENSG00000134627	PIWIL4	90	59.341	ENSPLAG00000007206	piwil1	100	47.045	Poecilia_latipinna
ENSG00000134627	PIWIL4	90	59.341	ENSPMEG00000003010	piwil1	100	47.313	Poecilia_mexicana
ENSG00000134627	PIWIL4	89	46.667	ENSPMEG00000018897	piwil2	72	37.139	Poecilia_mexicana
ENSG00000134627	PIWIL4	90	59.341	ENSPREG00000001990	piwil1	100	47.313	Poecilia_reticulata
ENSG00000134627	PIWIL4	89	46.667	ENSPREG00000019700	piwil2	72	37.027	Poecilia_reticulata
ENSG00000134627	PIWIL4	94	55.208	ENSPREG00000019001	-	100	55.208	Poecilia_reticulata
ENSG00000134627	PIWIL4	89	61.326	ENSPPYG00000005121	PIWIL1	100	48.786	Pongo_abelii
ENSG00000134627	PIWIL4	89	54.144	ENSPPYG00000011653	PIWIL3	100	39.002	Pongo_abelii
ENSG00000134627	PIWIL4	100	100.000	ENSPPYG00000003783	PIWIL4	100	98.826	Pongo_abelii
ENSG00000134627	PIWIL4	89	47.514	ENSPPYG00000018420	PIWIL2	78	38.845	Pongo_abelii
ENSG00000134627	PIWIL4	70	62.745	ENSPCAG00000014859	PIWIL2	62	62.745	Procavia_capensis
ENSG00000134627	PIWIL4	89	61.326	ENSPCAG00000002106	PIWIL1	77	59.314	Procavia_capensis
ENSG00000134627	PIWIL4	89	48.619	ENSPCOG00000019344	PIWIL2	86	37.646	Propithecus_coquereli
ENSG00000134627	PIWIL4	100	87.911	ENSPCOG00000022264	PIWIL4	100	87.911	Propithecus_coquereli
ENSG00000134627	PIWIL4	99	50.427	ENSPCOG00000007411	PIWIL1	100	46.269	Propithecus_coquereli
ENSG00000134627	PIWIL4	100	84.746	ENSPVAG00000007245	PIWIL4	99	78.286	Pteropus_vampyrus
ENSG00000134627	PIWIL4	89	56.667	ENSPVAG00000016875	PIWIL3	89	52.427	Pteropus_vampyrus
ENSG00000134627	PIWIL4	89	48.619	ENSPVAG00000009878	PIWIL2	72	46.377	Pteropus_vampyrus
ENSG00000134627	PIWIL4	89	60.773	ENSPVAG00000010030	PIWIL1	100	47.066	Pteropus_vampyrus
ENSG00000134627	PIWIL4	94	57.592	ENSPNYG00000019750	piwil1	100	46.697	Pundamilia_nyererei
ENSG00000134627	PIWIL4	89	47.778	ENSPNYG00000003305	piwil2	95	46.595	Pundamilia_nyererei
ENSG00000134627	PIWIL4	89	47.778	ENSPNAG00000004662	piwil2	72	37.927	Pygocentrus_nattereri
ENSG00000134627	PIWIL4	100	46.846	ENSPNAG00000012989	piwil1	100	47.106	Pygocentrus_nattereri
ENSG00000134627	PIWIL4	89	48.619	ENSRNOG00000009871	Piwil2	78	39.239	Rattus_norvegicus
ENSG00000134627	PIWIL4	99	51.282	ENSRNOG00000000934	Piwil1	100	49.076	Rattus_norvegicus
ENSG00000134627	PIWIL4	100	77.257	ENSRNOG00000009043	Piwil4	100	77.257	Rattus_norvegicus
ENSG00000134627	PIWIL4	90	47.802	ENSRBIG00000042426	PIWIL2	95	39.298	Rhinopithecus_bieti
ENSG00000134627	PIWIL4	100	97.300	ENSRBIG00000039745	PIWIL4	100	97.300	Rhinopithecus_bieti
ENSG00000134627	PIWIL4	89	61.326	ENSRBIG00000004595	PIWIL1	100	48.724	Rhinopithecus_bieti
ENSG00000134627	PIWIL4	100	97.653	ENSRROG00000015073	PIWIL4	100	97.653	Rhinopithecus_roxellana
ENSG00000134627	PIWIL4	89	48.066	ENSRROG00000037847	PIWIL2	78	38.714	Rhinopithecus_roxellana
ENSG00000134627	PIWIL4	89	61.326	ENSRROG00000030794	PIWIL1	100	48.724	Rhinopithecus_roxellana
ENSG00000134627	PIWIL4	99	52.991	ENSSBOG00000033094	PIWIL1	100	48.956	Saimiri_boliviensis_boliviensis
ENSG00000134627	PIWIL4	100	92.274	ENSSBOG00000024534	PIWIL4	100	92.732	Saimiri_boliviensis_boliviensis
ENSG00000134627	PIWIL4	89	48.619	ENSSBOG00000030819	PIWIL2	76	36.460	Saimiri_boliviensis_boliviensis
ENSG00000134627	PIWIL4	89	51.381	ENSSBOG00000005485	PIWIL3	100	40.078	Saimiri_boliviensis_boliviensis
ENSG00000134627	PIWIL4	89	48.619	ENSSHAG00000018279	PIWIL2	78	39.216	Sarcophilus_harrisii
ENSG00000134627	PIWIL4	99	53.846	ENSSHAG00000016260	PIWIL1	100	49.594	Sarcophilus_harrisii
ENSG00000134627	PIWIL4	67	38.562	ENSSHAG00000016064	-	95	39.442	Sarcophilus_harrisii
ENSG00000134627	PIWIL4	100	70.245	ENSSHAG00000017415	PIWIL4	100	70.245	Sarcophilus_harrisii
ENSG00000134627	PIWIL4	89	42.541	ENSSFOG00015012930	piwil2	65	36.614	Scleropages_formosus
ENSG00000134627	PIWIL4	100	47.899	ENSSFOG00015005758	piwil1	100	45.858	Scleropages_formosus
ENSG00000134627	PIWIL4	89	47.222	ENSSMAG00000019263	piwil2	71	36.745	Scophthalmus_maximus
ENSG00000134627	PIWIL4	90	57.692	ENSSMAG00000002912	piwil1	100	46.915	Scophthalmus_maximus
ENSG00000134627	PIWIL4	90	60.440	ENSSDUG00000022636	piwil1	100	48.834	Seriola_dumerili
ENSG00000134627	PIWIL4	89	47.222	ENSSDUG00000001859	piwil2	71	37.139	Seriola_dumerili
ENSG00000134627	PIWIL4	90	60.440	ENSSLDG00000013757	piwil1	100	47.856	Seriola_lalandi_dorsalis
ENSG00000134627	PIWIL4	89	47.222	ENSSLDG00000017738	piwil2	96	46.043	Seriola_lalandi_dorsalis
ENSG00000134627	PIWIL4	64	92.405	ENSSARG00000009859	-	61	93.590	Sorex_araneus
ENSG00000134627	PIWIL4	99	50.427	ENSSARG00000002678	PIWIL1	98	49.605	Sorex_araneus
ENSG00000134627	PIWIL4	89	48.619	ENSSARG00000013686	PIWIL2	79	36.072	Sorex_araneus
ENSG00000134627	PIWIL4	99	49.573	ENSSPUG00000013448	PIWIL1	95	47.783	Sphenodon_punctatus
ENSG00000134627	PIWIL4	98	67.839	ENSSPUG00000004259	PIWIL4	99	64.488	Sphenodon_punctatus
ENSG00000134627	PIWIL4	89	48.619	ENSSPUG00000014427	PIWIL2	94	49.097	Sphenodon_punctatus
ENSG00000134627	PIWIL4	99	45.154	ENSSPAG00000013460	piwil1	98	45.900	Stegastes_partitus
ENSG00000134627	PIWIL4	89	47.514	ENSSPAG00000019925	piwil2	84	35.696	Stegastes_partitus
ENSG00000134627	PIWIL4	89	61.326	ENSSSCG00000009749	PIWIL1	100	48.671	Sus_scrofa
ENSG00000134627	PIWIL4	89	48.066	ENSSSCG00000030228	PIWIL2	77	40.105	Sus_scrofa
ENSG00000134627	PIWIL4	92	53.439	ENSSSCG00000009950	-	96	40.204	Sus_scrofa
ENSG00000134627	PIWIL4	100	81.360	ENSSSCG00000014959	PIWIL4	100	81.360	Sus_scrofa
ENSG00000134627	PIWIL4	56	32.377	ENSTGUG00000014388	-	99	32.377	Taeniopygia_guttata
ENSG00000134627	PIWIL4	99	51.282	ENSTGUG00000004779	PIWIL1	99	51.759	Taeniopygia_guttata
ENSG00000134627	PIWIL4	89	45.304	ENSTRUG00000012599	piwil2	74	36.869	Takifugu_rubripes
ENSG00000134627	PIWIL4	90	58.791	ENSTRUG00000011149	piwil1	100	48.775	Takifugu_rubripes
ENSG00000134627	PIWIL4	90	45.946	ENSTNIG00000016749	piwil2	100	36.281	Tetraodon_nigroviridis
ENSG00000134627	PIWIL4	89	58.889	ENSTNIG00000003089	piwil1	100	47.972	Tetraodon_nigroviridis
ENSG00000134627	PIWIL4	63	53.125	ENSTNIG00000003088	-	71	51.980	Tetraodon_nigroviridis
ENSG00000134627	PIWIL4	76	36.667	ENSTBEG00000012061	-	50	34.783	Tupaia_belangeri
ENSG00000134627	PIWIL4	100	84.746	ENSTBEG00000013343	PIWIL4	91	80.759	Tupaia_belangeri
ENSG00000134627	PIWIL4	99	84.615	ENSTTRG00000010546	PIWIL4	100	82.277	Tursiops_truncatus
ENSG00000134627	PIWIL4	77	54.167	ENSTTRG00000012746	PIWIL2	68	54.167	Tursiops_truncatus
ENSG00000134627	PIWIL4	89	61.878	ENSTTRG00000016994	PIWIL1	100	48.260	Tursiops_truncatus
ENSG00000134627	PIWIL4	89	61.326	ENSUAMG00000000604	PIWIL1	100	48.786	Ursus_americanus
ENSG00000134627	PIWIL4	91	47.283	ENSUAMG00000005066	-	99	47.283	Ursus_americanus
ENSG00000134627	PIWIL4	100	81.356	ENSUAMG00000021173	PIWIL4	100	78.077	Ursus_americanus
ENSG00000134627	PIWIL4	89	61.326	ENSUMAG00000020294	PIWIL1	100	48.786	Ursus_maritimus
ENSG00000134627	PIWIL4	100	81.925	ENSUMAG00000007117	PIWIL4	100	81.925	Ursus_maritimus
ENSG00000134627	PIWIL4	89	48.619	ENSUMAG00000005016	PIWIL2	78	39.108	Ursus_maritimus
ENSG00000134627	PIWIL4	89	49.171	ENSVPAG00000010581	PIWIL2	78	39.529	Vicugna_pacos
ENSG00000134627	PIWIL4	99	83.761	ENSVPAG00000005839	PIWIL4	100	74.648	Vicugna_pacos
ENSG00000134627	PIWIL4	89	61.326	ENSVVUG00000025695	PIWIL1	91	48.671	Vulpes_vulpes
ENSG00000134627	PIWIL4	99	80.973	ENSVVUG00000011577	PIWIL4	100	82.524	Vulpes_vulpes
ENSG00000134627	PIWIL4	89	48.619	ENSVVUG00000005239	PIWIL2	78	39.450	Vulpes_vulpes
ENSG00000134627	PIWIL4	89	71.271	ENSXETG00000006411	piwil4	100	53.509	Xenopus_tropicalis
ENSG00000134627	PIWIL4	89	46.409	ENSXETG00000010533	piwil2	80	37.500	Xenopus_tropicalis
ENSG00000134627	PIWIL4	99	48.718	ENSXETG00000012572	piwil3	100	44.966	Xenopus_tropicalis
ENSG00000134627	PIWIL4	89	45.856	ENSXCOG00000015207	piwil2	95	45.161	Xiphophorus_couchianus
ENSG00000134627	PIWIL4	89	46.111	ENSXMAG00000005034	piwil2	72	36.614	Xiphophorus_maculatus
ENSG00000134627	PIWIL4	90	60.989	ENSXMAG00000000110	piwil1	100	47.547	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004521	endoribonuclease activity	-	ISS	Function
GO:0005634	nucleus	28025795.	IDA	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005737	cytoplasm	28025795.	IDA	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0006417	regulation of translation	-	IEA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0007283	spermatogenesis	-	ISS	Process
GO:0010529	negative regulation of transposition	-	ISS	Process
GO:0010669	epithelial structure maintenance	28025795.	IMP	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0031047	gene silencing by RNA	-	ISS	Process
GO:0034584	piRNA binding	25038252.	IDA	Function
GO:0034584	piRNA binding	-	ISS	Function
GO:0034587	piRNA metabolic process	-	ISS	Process
GO:0043046	DNA methylation involved in gamete generation	-	ISS	Process
GO:0043186	P granule	-	ISS	Component
GO:0051321	meiotic cell cycle	-	IEA	Process
GO:0071547	piP-body	-	ISS	Component
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
22748119	Expression of human Piwi-like genes is associated with prognosis for soft tissue sarcoma patients.	BMC Cancer	2012 Jun 29	Greither T	doi: 10.1186/1471-2407-12-272.
20146808	Argonaute proteins: potential biomarkers for human colon cancer.	BMC Cancer	2010 Feb 10	Li L	doi: 10.1186/1471-2407-10-38.
27058823	CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis.	Mol Ther	2016 Aug	Zheng J	doi: 10.1038/mt.2016.71
26957540	The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer.	J Biol Chem	2016 May 13	Wang Z	doi: 10.1074/jbc.M116.723239
22483988	PIWIL4 regulates cervical cancer cell line growth and is involved in down-regulating the expression of p14ARF and p53.	FEBS Lett	2012 May 7	Su C	doi: 10.1016/j.febslet.2012.03.053
25038252	The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells.	Nucleic Acids Res	2014 Aug	Keam SP	doi: 10.1093/nar/gku620
30226541	The role of 17βestradiolinduced upregulation of Piwilike4 in modulating gene expression and motility in breast cancer cells.	Oncol Rep	2018 Nov	Heng ZSL	doi: 10.3892/or.2018.6676

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr11	94607603	Silent	novel	C601C	0.89
BLCA	chr11	94577388	Missense_Mutation	NA	R137G	0.07	PAZ
BLCA	chr11	94601954	Missense_Mutation	NA	G514R	0.19
BLCA	chr11	94595373	Silent	NA	L405L	0.15
BLCA	chr11	94619832	Silent	novel	V747V	0.49
BLCA	chr11	94583447	Splice_Site	NA	X172_splice	0.29
BLCA	chr11	94568796	Missense_Mutation	novel	I52V	0.1	PAZ
BLCA	chr11	94607511	Missense_Mutation	NA	P571S	0.35
BLCA	chr11	94620980	Silent	novel	L849L	0.1
BLCA	chr11	94597887	Missense_Mutation	novel	S451L	0.45
BLCA	chr11	94620012	Silent	novel	L770L	0.42
BRCA	chr11	94585498	Missense_Mutation	novel	S230L	0.07
BRCA	chr11	94593610	Silent	novel	A373A	0.06
BRCA	chr11	94575017	Missense_Mutation	NA	S62C	0.21	PAZ
BRCA	chr11	94597837	Missense_Mutation	NA	W434C	0.42
BRCA	chr11	94585494	Missense_Mutation	NA	P229S	0.16
BRCA	chr11	94589217	Silent	novel	V337V	0.1
BRCA	chr11	94608328	Intron	novel		0.27
CESC	chr11	94603982	Splice_Site	NA	X522_splice	0.21
CESC	chr11	94593596	Missense_Mutation	NA	E369K	0.15
CESC	chr11	94568776	Missense_Mutation	novel	G45D	0.5	PAZ
CESC	chr11	94601890	Silent	rs775511179	S492S	0.32
CESC	chr11	94583472	Missense_Mutation	NA	Q180E	0.24	PAZ
CESC	chr11	94595416	Missense_Mutation	novel	N420D	0.22
CESC	chr11	94621034	3'UTR	novel		0.71
CESC	chr11	94621035	3'UTR	novel		0.71
COAD	chr11	94577389	Missense_Mutation	NA	R137I	0.3	PAZ
COAD	chr11	94583545	Missense_Mutation	novel	Q204R	0.07
COAD	chr11	94587084	Missense_Mutation	NA	S251P	0.39
COAD	chr11	94620021	Frame_Shift_Del	novel	*V774Wfs21**	0.16
COAD	chr11	94583535	Missense_Mutation	rs554791169	V201M	0.36
COAD	chr11	94607615	Silent	novel	G605G	0.38
COAD	chr11	94621104	3'UTR	novel		0.32
COAD	chr11	94619771	Missense_Mutation	rs777500348	S727L	0.37
COAD	chr11	94620143	Missense_Mutation	rs200034919	P814L	0.17
COAD	chr11	94597872	Missense_Mutation	novel	G446V	0.3
COAD	chr11	94577297	Silent	novel	V106V	0.3
COAD	chr11	94607610	Missense_Mutation	rs371297833	G604R	0.28
COAD	chr11	94595352	Silent	NA	A398A	0.26
COAD	chr11	94608392	Intron	novel		0.3
DLBC	chr11	94619995	Splice_Site	novel	X765_splice	0.5
GBM	chr11	94608655	Missense_Mutation	novel	C638S	0.07
GBM	chr11	94601890	Silent	rs775511179	S492S	0.34
GBM	chr11	94618006	Missense_Mutation	novel	I689M	0.1
GBM	chr11	94577450	Silent	NA	F157F	0.25
GBM	chr11	94593518	Nonsense_Mutation	novel	Q343*	0.41
GBM	chr11	94607439	Missense_Mutation	rs753261810	V547I	0.18
GBM	chr11	94575073	Missense_Mutation	novel	M81L	0.08	PAZ
HNSC	chr11	94616534	Missense_Mutation	novel	V662A	0.25
HNSC	chr11	94608601	Missense_Mutation	novel	V620I	0.26
HNSC	chr11	94597895	Missense_Mutation	novel	I454L	0.31
HNSC	chr11	94607573	Silent	rs774449382	I591I	0.3
KICH	chr11	94619876	Missense_Mutation	rs749598394	R762H	0.57
KIRC	chr11	94575019	Missense_Mutation	NA	G63R	0.29	PAZ
KIRC	chr11	94575130	Missense_Mutation	novel	G100C	0.04	PAZ
KIRP	chr11	94608639	Silent	rs770380977	D632D	0.4
KIRP	chr11	94607571	Missense_Mutation	NA	I591V	0.4
KIRP	chr11	94567562	Missense_Mutation	novel	S15N	0.36
LAML	chr11	94619849	Missense_Mutation	novel	G753D	0.06
LAML	chr11	94567570	Missense_Mutation	NA	A18P	0.26
LGG	chr11	94608498	Intron	novel		0.25
LGG	chr11	94595338	Nonsense_Mutation	novel	Q394*	0.05
LIHC	chr11	94620887	Missense_Mutation	NA	S818R	0.23
LIHC	chr11	94585504	Missense_Mutation	NA	P232Q	0.82
LIHC	chr11	94620893	Silent	NA	P820P	0.45
LIHC	chr11	94620050	Missense_Mutation	NA	T783N	0.15
LIHC	chr11	94583540	Nonsense_Mutation	NA	C202*	0.4
LIHC	chr11	94575089	Missense_Mutation	novel	C86S	0.41	PAZ
LIHC	chr11	94619833	Missense_Mutation	NA	Q748K	0.35
LUAD	chr11	94597831	Missense_Mutation	novel	E432D	0.11
LUAD	chr11	94577388	Missense_Mutation	NA	R137G	0.3	PAZ
LUAD	chr11	94621126	3'UTR	novel		0.67
LUAD	chr11	94621127	3'UTR	novel		0.67
LUAD	chr11	94617969	Missense_Mutation	novel	W677L	0.26
LUAD	chr11	94577303	Silent	NA	L108L	0.09
LUAD	chr11	94589125	Missense_Mutation	NA	N307D	0.19
LUAD	chr11	94583516	Silent	novel	E194E	0.07
LUAD	chr11	94620026	Frame_Shift_Del	novel	*C776Afs19**	0.06
LUAD	chr11	94608658	Missense_Mutation	NA	V639L	0.16
LUAD	chr11	94575069	Missense_Mutation	NA	D79E	0.41	PAZ
LUAD	chr11	94587148	Missense_Mutation	rs752333176	T272M	0.16
LUAD	chr11	94587237	Missense_Mutation	rs144295355	V302I	0.24
LUAD	chr11	94568777	Silent	novel	G45G	0.05
LUSC	chr11	94595402	Missense_Mutation	novel	A415V	0.17
LUSC	chr11	94619841	Silent	novel	P750P	0.27
LUSC	chr11	94621127	3'UTR	novel		0.31
LUSC	chr11	94589153	Missense_Mutation	novel	I316S	0.07
LUSC	chr11	94585484	Silent	novel	N225N	0.15
LUSC	chr11	94567557	Silent	rs781138817	A13A	0.19
LUSC	chr11	94607552	Silent	novel	K584K	0.52
LUSC	chr11	94618001	Missense_Mutation	rs767622103	I688L	0.18
OV	chr11	94608422	Intron	novel		0.24
OV	chr11	94621043	3'UTR	novel		0.42
OV	chr11	94583556	Missense_Mutation	novel	I208V	0.08
PAAD	chr11	94577281	Missense_Mutation	novel	S101Y	0.13	PAZ
READ	chr11	94583497	Missense_Mutation	novel	T188S	0.05	PAZ
READ	chr11	94618029	Missense_Mutation	NA	D697G	0.17
READ	chr11	94597859	Missense_Mutation	rs750835307	I442V	0.34
READ	chr11	94608480	Intron	novel		0.38
READ	chr11	94620951	Nonsense_Mutation	NA	E840*	0.35
SKCM	chr11	94595338	Nonsense_Mutation	novel	Q394*	0.57
SKCM	chr11	94567595	Missense_Mutation	rs550779043	A26V	0.54	PAZ
SKCM	chr11	94619859	Silent	NA	V756V	0.14
SKCM	chr11	94577374	Missense_Mutation	NA	P132L	0.31	PAZ
SKCM	chr11	94608592	Silent	NA	L617L	0.09
SKCM	chr11	94621027	3'UTR	novel		0.33
SKCM	chr11	94585457	Missense_Mutation	novel	K216N	0.44
SKCM	chr11	94607532	Missense_Mutation	NA	L578F	0.36
SKCM	chr11	94619815	Missense_Mutation	rs766849717	E742K	0.32
SKCM	chr11	94585475	Silent	NA	I222I	0.18
SKCM	chr11	94608591	Silent	rs750573373	S616S	0.29
SKCM	chr11	94587055	Missense_Mutation	NA	S241F	0.29
SKCM	chr11	94593607	Silent	NA	L372L	0.1
SKCM	chr11	94619815	Missense_Mutation	rs766849717	E742K	0.49
SKCM	chr11	94620008	Missense_Mutation	novel	Y769C	0.15
SKCM	chr11	94619775	Silent	NA	V728V	0.6
SKCM	chr11	94601807	Missense_Mutation	NA	S465T	0.19
SKCM	chr11	94583564	Silent	novel	F210F	0.37
SKCM	chr11	94583517	Silent	NA	L195L	0.39
SKCM	chr11	94619842	Missense_Mutation	NA	P751S	0.2
SKCM	chr11	94589169	Silent	NA	K321K	0.21
STAD	chr11	94587230	Silent	novel	G299G	0.14
STAD	chr11	94583520	Missense_Mutation	novel	P196S	0.47
STAD	chr11	94601974	Frame_Shift_Ins	novel	*I522Nfs13**	0.37
STAD	chr11	94620078	Silent	rs201026049	N792N	0.42
STAD	chr11	94595369	Missense_Mutation	rs760210104	R404H	0.1
STAD	chr11	94607509	Missense_Mutation	NA	C570Y	0.27
STAD	chr11	94575058	Missense_Mutation	NA	N76H	0.1	PAZ
STAD	chr11	94593538	Silent	rs575492946	S349S	0.23
STAD	chr11	94607458	Missense_Mutation	NA	S553Y	0.25
STAD	chr11	94593626	Missense_Mutation	NA	L379F	0.12
STAD	chr11	94595370	Silent	NA	R404R	0.1
STAD	chr11	94587072	Missense_Mutation	rs770456343	A247T	0.15
STAD	chr11	94593608	Missense_Mutation	rs758423897	A373T	0.21
UCEC	chr11	94607468	Missense_Mutation	NA	K556N	0.29
UCEC	chr11	94608536	Intron	novel		0.06
UCEC	chr11	94567551	Silent	rs751345096	G11G	0.45
UCEC	chr11	94589128	Missense_Mutation	novel	N308D	0.25
UCEC	chr11	94607499	Missense_Mutation	novel	S567R	0.48
UCEC	chr11	94577487	Nonsense_Mutation	NA	E170*	0.28	PAZ
UCEC	chr11	94593582	Missense_Mutation	NA	R364I	0.43
UCEC	chr11	94601835	Missense_Mutation	rs748942147	R474Q	0.39
UCEC	chr11	94595369	Missense_Mutation	rs760210104	R404H	0.13
UCEC	chr11	94589132	Missense_Mutation	NA	R309I	0.36
UCEC	chr11	94593524	Missense_Mutation	novel	D345N	0.36
UCEC	chr11	94620102	Missense_Mutation	novel	Q800H	0.41
UCEC	chr11	94620989	Silent	novel	L852L	0.38
UCEC	chr11	94589191	Missense_Mutation	rs769687573	R329W	0.4
UCEC	chr11	94601834	Nonsense_Mutation	NA	R474*	0.34
UCEC	chr11	94620951	Nonsense_Mutation	NA	E840*	0.39
UCEC	chr11	94619852	Missense_Mutation	NA	T754N	0.13
UCEC	chr11	94568794	Missense_Mutation	NA	R51K	0.44	PAZ
UCEC	chr11	94608639	Silent	rs770380977	D632D	0.33
UCEC	chr11	94593538	Silent	rs575492946	S349S	0.24
UCEC	chr11	94617998	Missense_Mutation	rs138314594	R687W	0.38
UCEC	chr11	94619998	Missense_Mutation	NA	Y766H	0.38
UCEC	chr11	94568762	Silent	novel	A40A	0.35
UCEC	chr11	94601845	Missense_Mutation	novel	K477N	0.41
UCEC	chr11	94583520	Missense_Mutation	novel	P196S	0.24
UCEC	chr11	94601965	Silent	novel	V517V	0.24
UCEC	chr11	94608439	Intron	novel		0.43
UCEC	chr11	94583503	Missense_Mutation	novel	T190S	0.49
UCEC	chr11	94601882	Silent	novel	L490L	0.36
UCEC	chr11	94619808	Missense_Mutation	novel	F739L	0.4
UCEC	chr11	94608603	Silent	novel	V620V	0.19
UCEC	chr11	94567428	5'UTR	novel		0.29
UCEC	chr11	94577439	Missense_Mutation	novel	A154T	0.37	PAZ
UCEC	chr11	94616534	Missense_Mutation	novel	V662A	0.48
UCEC	chr11	94620923	Silent	novel	T830T	0.42
UCEC	chr11	94597863	Missense_Mutation	novel	S443Y	0.52
UCEC	chr11	94608576	Splice_Region	novel		0.16
UCEC	chr11	94593537	Missense_Mutation	rs185092971	S349L	0.38
UCEC	chr11	94601959	Missense_Mutation	novel	F515L	0.31
UCEC	chr11	94577316	Frame_Shift_Del	novel	F113*	0.26	PAZ
UCEC	chr11	94568780	Missense_Mutation	novel	F46L	0.17	PAZ
UCEC	chr11	94575097	Missense_Mutation	novel	E89K	0.43	PAZ
UCEC	chr11	94595351	Missense_Mutation	rs533859561	A398V	0.34
UCEC	chr11	94575091	Missense_Mutation	novel	T87A	0.26	PAZ
UCEC	chr11	94589142	Silent	novel	S312S	0.23
UCEC	chr11	94583470	Missense_Mutation	novel	T179N	0.47	PAZ
UCEC	chr11	94593551	Missense_Mutation	rs752357680	P354S	0.34
UCEC	chr11	94617998	Missense_Mutation	rs138314594	R687W	0.5
UCEC	chr11	94617983	Missense_Mutation	NA	H682D	0.5
UCEC	chr11	94583539	Missense_Mutation	novel	C202Y	0.32
UCEC	chr11	94577357	Nonsense_Mutation	novel	Y126*	0.41	PAZ
UCEC	chr11	94589191	Missense_Mutation	rs769687573	R329W	0.42
UCEC	chr11	94601835	Missense_Mutation	rs748942147	R474Q	0.06
UCEC	chr11	94608577	Splice_Region	novel		0.05
UCEC	chr11	94567438	5'UTR	novel		0.35
UCEC	chr11	94597848	Missense_Mutation	NA	F438S	0.6
UCEC	chr11	94607441	Splice_Region	NA	V547V	0.31
UCEC	chr11	94621126	3'UTR	novel		0.21
UCEC	chr11	94621127	3'UTR	novel		0.21
UCEC	chr11	94575057	Missense_Mutation	NA	K75N	0.47	PAZ
UCEC	chr11	94587069	Missense_Mutation	NA	F246L	0.48
UCEC	chr11	94619824	Missense_Mutation	rs374387055	R745C	0.51
UCEC	chr11	94621105	3'UTR	novel		0.32
UCEC	chr11	94607586	Missense_Mutation	rs377761223	A596T	0.32
UCEC	chr11	94577487	Nonsense_Mutation	NA	E170*	0.32	PAZ
UCEC	chr11	94593528	Missense_Mutation	novel	I346T	0.37
UCEC	chr11	94567558	Missense_Mutation	novel	R14C	0.32
UCEC	chr11	94577313	Missense_Mutation	novel	L112I	0.19	PAZ
UCEC	chr11	94583540	Silent	novel	C202C	0.4
UCEC	chr11	94595383	Missense_Mutation	novel	G409C	0.1
UCEC	chr11	94601917	Missense_Mutation	novel	S501R	0.2
UCEC	chr11	94621008	3'UTR	novel		0.24
UCEC	chr11	94568737	Missense_Mutation	novel	S32Y	0.32	PAZ
UCEC	chr11	94608639	Silent	rs770380977	D632D	0.26
UCEC	chr11	94574998	Splice_Site	novel	X56_splice	0.49
UCEC	chr11	94577450	Silent	NA	F157F	0.49
UCEC	chr11	94575087	Silent	novel	I85I	0.3
UCEC	chr11	94593631	Silent	novel	C380C	0.4
UCS	chr11	94577450	Silent	NA	F157F	0.41
UCS	chr11	94585455	Missense_Mutation	novel	K216Q	0.32
UCS	chr11	94589205	Missense_Mutation	novel	E333D	0.31

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ESCA	AMP	0.1467	0.018342
LUSC	DEL	0.2236	0.00011543
TGCT	DEL	0.7333	0.21504
UCS	DEL	0.3929	0.061343

Survival Analysis

Cancer	P-value	Q-value
ACC	0.00073	Kaplan-Meier Survival Analysis
HNSC	0.0013	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
READ	0.042	Kaplan-Meier Survival Analysis
LAML	0.03	Kaplan-Meier Survival Analysis
UCEC	0.028	Kaplan-Meier Survival Analysis
CHOL	0.00011	Kaplan-Meier Survival Analysis
UVM	0.033	Kaplan-Meier Survival Analysis