EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000135372 (Gene tree)
Gene ID: 55226
Gene Symbol: NAT10
Alias: hALP|FLJ10774|FLJ12179|NET43|KIAA1709|Kre33
Full Name: N-acetyltransferase 10
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 45,471 bases
Position: chr11:34,105,564-34,151,034
Accession: 29830
RBP type: canonical RBP
Summary: The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation, tRNA acetylation, the biosynthesis of 18S rRNA, and the enhancement of nuclear architecture and chromatin organization. [provided by RefSeq, Oct 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000479141	tRNA_bind_2	PF13725.6	3.1e-79	1	1
ENSP00000433011	tRNA_bind_2	PF13725.6	7.6e-79	1	1
ENSP00000257829	tRNA_bind_2	PF13725.6	8.6e-79	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21177859	hALP, a novel transcriptional U three protein (t-UTP), activates RNA polymerase I transcription by binding and acetylating the upstream binding factor (UBF).	J Biol Chem	2011 Mar 4	Kong R	doi: 10.1074/jbc.M110.173393

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000615292	NAT10-210	3329	-	ENSP00000479141	834 (aa)	-	A0A087WV29
ENST00000529523	NAT10-203	561	-	ENSP00000435569	145 (aa)	-	E9PJN6
ENST00000527971	NAT10-202	1600	-	ENSP00000437324	288 (aa)	-	E9PMU0
ENST00000532503	NAT10-207	556	-	-	- (aa)	-	-
ENST00000534509	NAT10-209	420	-	-	- (aa)	-	-
ENST00000257829	NAT10-201	4002	-	ENSP00000257829	1025 (aa)	-	Q9H0A0
ENST00000531723	NAT10-206	528	-	-	- (aa)	-	-
ENST00000530017	NAT10-204	543	-	-	- (aa)	-	-
ENST00000532555	NAT10-208	615	-	-	- (aa)	-	-
ENST00000531159	NAT10-205	3436	-	ENSP00000433011	953 (aa)	-	Q9H0A0

Gene Model

Click here to download ENSG00000135372's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000135372	Blood Pressure	7.8870000E-005	-
ENSG00000135372	Blood Pressure	1.6594968E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135372's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000135372	NAT10	99	88.811	ENSAPOG00000010634	nat10	98	81.238	Acanthochromis_polyacanthus
ENSG00000135372	NAT10	100	99.310	ENSAMEG00000008124	NAT10	99	95.669	Ailuropoda_melanoleuca
ENSG00000135372	NAT10	99	86.014	ENSACIG00000017852	nat10	98	77.416	Amphilophus_citrinellus
ENSG00000135372	NAT10	99	88.811	ENSAOCG00000004556	nat10	98	81.238	Amphiprion_ocellaris
ENSG00000135372	NAT10	99	88.811	ENSAPEG00000001116	nat10	98	81.238	Amphiprion_percula
ENSG00000135372	NAT10	99	88.811	ENSATEG00000015592	nat10	98	80.747	Anabas_testudineus
ENSG00000135372	NAT10	99	87.334	ENSAPLG00000007638	NAT10	99	87.988	Anas_platyrhynchos
ENSG00000135372	NAT10	100	93.103	ENSACAG00000013465	NAT10	99	86.350	Anolis_carolinensis
ENSG00000135372	NAT10	100	99.310	ENSANAG00000026850	NAT10	100	98.343	Aotus_nancymaae
ENSG00000135372	NAT10	99	87.413	ENSACLG00000007336	nat10	98	80.157	Astatotilapia_calliptera
ENSG00000135372	NAT10	99	91.608	ENSAMXG00000038087	nat10	99	83.125	Astyanax_mexicanus
ENSG00000135372	NAT10	100	98.621	ENSBTAG00000016747	NAT10	100	96.394	Bos_taurus
ENSG00000135372	NAT10	99	64.336	WBGene00018866	nath-10	95	54.845	Caenorhabditis_elegans
ENSG00000135372	NAT10	100	98.621	ENSCJAG00000010585	NAT10	100	97.953	Callithrix_jacchus
ENSG00000135372	NAT10	100	98.621	ENSCAFG00000007028	NAT10	99	95.768	Canis_familiaris
ENSG00000135372	NAT10	100	98.621	ENSCAFG00020004530	NAT10	99	96.259	Canis_lupus_dingo
ENSG00000135372	NAT10	100	99.310	ENSCHIG00000026081	NAT10	100	96.491	Capra_hircus
ENSG00000135372	NAT10	100	95.862	ENSTSYG00000013519	NAT10	99	89.469	Carlito_syrichta
ENSG00000135372	NAT10	100	99.310	ENSCPOG00000015736	NAT10	99	93.799	Cavia_porcellus
ENSG00000135372	NAT10	100	98.621	ENSCCAG00000003512	NAT10	100	98.148	Cebus_capucinus
ENSG00000135372	NAT10	100	100.000	ENSCATG00000037820	NAT10	100	98.928	Cercocebus_atys
ENSG00000135372	NAT10	100	98.621	ENSCLAG00000016692	NAT10	99	94.488	Chinchilla_lanigera
ENSG00000135372	NAT10	100	100.000	ENSCSAG00000005383	NAT10	100	98.635	Chlorocebus_sabaeus
ENSG00000135372	NAT10	100	98.621	ENSCHOG00000001629	NAT10	87	92.308	Choloepus_hoffmanni
ENSG00000135372	NAT10	100	94.483	ENSCPBG00000012518	NAT10	99	88.069	Chrysemys_picta_bellii
ENSG00000135372	NAT10	99	78.322	ENSCING00000003567	-	99	64.907	Ciona_intestinalis
ENSG00000135372	NAT10	100	99.310	ENSCANG00000033310	NAT10	100	98.830	Colobus_angolensis_palliatus
ENSG00000135372	NAT10	100	97.931	ENSCGRG00001010534	NAT10	99	95.956	Cricetulus_griseus_chok1gshd
ENSG00000135372	NAT10	100	97.931	ENSCGRG00000012271	NAT10	99	95.567	Cricetulus_griseus_crigri
ENSG00000135372	NAT10	99	88.811	ENSCSEG00000013106	nat10	98	83.922	Cynoglossus_semilaevis
ENSG00000135372	NAT10	99	90.909	ENSDARG00000054259	nat10	99	80.826	Danio_rerio
ENSG00000135372	NAT10	100	98.621	ENSDNOG00000042452	NAT10	99	95.005	Dasypus_novemcinctus
ENSG00000135372	NAT10	100	99.310	ENSDORG00000006567	Nat10	99	94.985	Dipodomys_ordii
ENSG00000135372	NAT10	100	59.589	FBgn0027330	l(1)G0020	99	52.947	Drosophila_melanogaster
ENSG00000135372	NAT10	82	76.748	ENSETEG00000020037	-	77	83.333	Echinops_telfairi
ENSG00000135372	NAT10	100	85.517	ENSEBUG00000012661	nat10	99	75.889	Eptatretus_burgeri
ENSG00000135372	NAT10	100	98.621	ENSEASG00005020208	NAT10	99	95.276	Equus_asinus_asinus
ENSG00000135372	NAT10	100	98.621	ENSECAG00000011621	NAT10	99	95.624	Equus_caballus
ENSG00000135372	NAT10	99	91.315	ENSEEUG00000006899	NAT10	99	86.122	Erinaceus_europaeus
ENSG00000135372	NAT10	99	90.909	ENSELUG00000000189	nat10	97	84.775	Esox_lucius
ENSG00000135372	NAT10	100	99.310	ENSFCAG00000002028	NAT10	100	96.199	Felis_catus
ENSG00000135372	NAT10	100	96.552	ENSFALG00000001264	NAT10	96	87.413	Ficedula_albicollis
ENSG00000135372	NAT10	100	97.931	ENSFDAG00000010525	NAT10	99	93.799	Fukomys_damarensis
ENSG00000135372	NAT10	100	86.301	ENSFHEG00000009197	NAT10	99	79.668	Fundulus_heteroclitus
ENSG00000135372	NAT10	99	90.909	ENSGMOG00000002783	nat10	98	77.426	Gadus_morhua
ENSG00000135372	NAT10	100	95.862	ENSGALG00000014573	NAT10	99	87.909	Gallus_gallus
ENSG00000135372	NAT10	99	89.510	ENSGACG00000009849	nat10	96	80.943	Gasterosteus_aculeatus
ENSG00000135372	NAT10	100	91.034	ENSGAGG00000002160	NAT10	98	86.369	Gopherus_agassizii
ENSG00000135372	NAT10	100	100.000	ENSGGOG00000014560	NAT10	100	99.512	Gorilla_gorilla
ENSG00000135372	NAT10	99	87.413	ENSHBUG00000003769	nat10	98	82.704	Haplochromis_burtoni
ENSG00000135372	NAT10	100	98.621	ENSHGLG00000016891	NAT10	99	93.996	Heterocephalus_glaber_female
ENSG00000135372	NAT10	100	98.621	ENSHGLG00100016949	NAT10	99	93.996	Heterocephalus_glaber_male
ENSG00000135372	NAT10	99	88.811	ENSHCOG00000016765	nat10	96	80.380	Hippocampus_comes
ENSG00000135372	NAT10	100	98.621	ENSSTOG00000001817	-	100	96.394	Ictidomys_tridecemlineatus
ENSG00000135372	NAT10	100	99.310	ENSJJAG00000023042	Nat10	99	95.768	Jaculus_jaculus
ENSG00000135372	NAT10	99	88.112	ENSKMAG00000001467	nat10	98	80.059	Kryptolebias_marmoratus
ENSG00000135372	NAT10	99	88.112	ENSLBEG00000013233	nat10	98	80.177	Labrus_bergylta
ENSG00000135372	NAT10	100	89.655	ENSLACG00000004636	NAT10	99	82.417	Latimeria_chalumnae
ENSG00000135372	NAT10	100	88.966	ENSLOCG00000002896	nat10	99	82.917	Lepisosteus_oculatus
ENSG00000135372	NAT10	100	98.621	ENSLAFG00000012393	NAT10	99	95.383	Loxodonta_africana
ENSG00000135372	NAT10	100	100.000	ENSMFAG00000041013	NAT10	100	98.928	Macaca_fascicularis
ENSG00000135372	NAT10	100	100.000	ENSMMUG00000021646	NAT10	100	99.025	Macaca_mulatta
ENSG00000135372	NAT10	100	100.000	ENSMNEG00000041284	NAT10	100	98.733	Macaca_nemestrina
ENSG00000135372	NAT10	100	100.000	ENSMLEG00000017199	NAT10	100	95.224	Mandrillus_leucophaeus
ENSG00000135372	NAT10	99	88.112	ENSMAMG00000000316	nat10	98	80.373	Mastacembelus_armatus
ENSG00000135372	NAT10	99	87.413	ENSMZEG00005004998	nat10	98	81.486	Maylandia_zebra
ENSG00000135372	NAT10	98	86.659	ENSMGAG00000010206	NAT10	99	85.525	Meleagris_gallopavo
ENSG00000135372	NAT10	97	93.696	ENSMAUG00000010653	-	99	93.921	Mesocricetus_auratus
ENSG00000135372	NAT10	100	100.000	ENSMICG00000003627	NAT10	100	96.523	Microcebus_murinus
ENSG00000135372	NAT10	100	97.931	ENSMOCG00000021454	Nat10	99	95.172	Microtus_ochrogaster
ENSG00000135372	NAT10	90	80.657	ENSMMOG00000012266	nat10	99	81.022	Mola_mola
ENSG00000135372	NAT10	100	91.724	ENSMODG00000009890	NAT10	99	88.397	Monodelphis_domestica
ENSG00000135372	NAT10	99	86.014	ENSMALG00000008766	nat10	96	80.321	Monopterus_albus
ENSG00000135372	NAT10	100	97.241	ENSMUSG00000027185	Nat10	99	95.558	Mus_musculus
ENSG00000135372	NAT10	100	96.552	MGP_PahariEiJ_G0025454	Nat10	99	95.064	Mus_pahari
ENSG00000135372	NAT10	100	97.241	MGP_SPRETEiJ_G0024928	Nat10	99	95.163	Mus_spretus
ENSG00000135372	NAT10	100	99.310	ENSMPUG00000011636	NAT10	99	95.472	Mustela_putorius_furo
ENSG00000135372	NAT10	100	99.310	ENSMLUG00000016473	NAT10	99	94.892	Myotis_lucifugus
ENSG00000135372	NAT10	100	97.241	ENSNGAG00000013486	Nat10	99	95.276	Nannospalax_galili
ENSG00000135372	NAT10	99	87.413	ENSNBRG00000002262	nat10	99	80.255	Neolamprologus_brichardi
ENSG00000135372	NAT10	100	99.310	ENSNLEG00000017916	NAT10	100	99.220	Nomascus_leucogenys
ENSG00000135372	NAT10	75	95.413	ENSMEUG00000012722	-	80	89.844	Notamacropus_eugenii
ENSG00000135372	NAT10	100	97.931	ENSOPRG00000009758	NAT10	100	94.135	Ochotona_princeps
ENSG00000135372	NAT10	100	98.621	ENSODEG00000017069	NAT10	99	94.778	Octodon_degus
ENSG00000135372	NAT10	99	88.112	ENSONIG00000008445	nat10	98	80.157	Oreochromis_niloticus
ENSG00000135372	NAT10	100	95.862	ENSOANG00000007400	-	99	90.597	Ornithorhynchus_anatinus
ENSG00000135372	NAT10	100	97.931	ENSOCUG00000001398	NAT10	100	96.461	Oryctolagus_cuniculus
ENSG00000135372	NAT10	99	88.811	ENSORLG00000004830	nat10	96	81.124	Oryzias_latipes
ENSG00000135372	NAT10	99	88.811	ENSORLG00020012458	nat10	96	80.924	Oryzias_latipes_hni
ENSG00000135372	NAT10	99	88.811	ENSORLG00015005731	nat10	96	80.924	Oryzias_latipes_hsok
ENSG00000135372	NAT10	99	88.811	ENSOMEG00000013901	nat10	94	82.674	Oryzias_melastigma
ENSG00000135372	NAT10	100	100.000	ENSOGAG00000016737	NAT10	100	97.076	Otolemur_garnettii
ENSG00000135372	NAT10	100	99.310	ENSOARG00000018290	NAT10	100	96.491	Ovis_aries
ENSG00000135372	NAT10	100	100.000	ENSPPAG00000036069	NAT10	100	99.707	Pan_paniscus
ENSG00000135372	NAT10	100	99.310	ENSPPRG00000010254	NAT10	99	96.161	Panthera_pardus
ENSG00000135372	NAT10	100	99.310	ENSPTIG00000010705	NAT10	99	96.161	Panthera_tigris_altaica
ENSG00000135372	NAT10	100	100.000	ENSPTRG00000003494	NAT10	100	99.610	Pan_troglodytes
ENSG00000135372	NAT10	100	99.310	ENSPANG00000013723	NAT10	100	99.123	Papio_anubis
ENSG00000135372	NAT10	99	88.811	ENSPKIG00000004093	nat10	99	82.347	Paramormyrops_kingsleyae
ENSG00000135372	NAT10	100	93.103	ENSPSIG00000006469	NAT10	99	85.025	Pelodiscus_sinensis
ENSG00000135372	NAT10	100	98.621	ENSPEMG00000009451	Nat10	99	95.271	Peromyscus_maniculatus_bairdii
ENSG00000135372	NAT10	100	87.586	ENSPMAG00000003621	nat10	97	79.300	Petromyzon_marinus
ENSG00000135372	NAT10	100	93.793	ENSPCIG00000026378	NAT10	98	89.792	Phascolarctos_cinereus
ENSG00000135372	NAT10	99	88.112	ENSPFOG00000012532	nat10	98	80.157	Poecilia_formosa
ENSG00000135372	NAT10	99	88.112	ENSPLAG00000014361	nat10	98	80.157	Poecilia_latipinna
ENSG00000135372	NAT10	99	88.112	ENSPMEG00000003182	nat10	98	80.157	Poecilia_mexicana
ENSG00000135372	NAT10	99	77.925	ENSPREG00000016112	nat10	97	79.031	Poecilia_reticulata
ENSG00000135372	NAT10	99	85.163	ENSPCAG00000004327	NAT10	99	80.816	Procavia_capensis
ENSG00000135372	NAT10	100	100.000	ENSPCOG00000009633	NAT10	100	97.076	Propithecus_coquereli
ENSG00000135372	NAT10	100	99.310	ENSPVAG00000005560	NAT10	92	97.829	Pteropus_vampyrus
ENSG00000135372	NAT10	99	87.413	ENSPNYG00000021872	nat10	98	82.826	Pundamilia_nyererei
ENSG00000135372	NAT10	99	88.112	ENSPNAG00000019299	nat10	99	81.084	Pygocentrus_nattereri
ENSG00000135372	NAT10	100	97.931	ENSRNOG00000008663	Nat10	99	95.639	Rattus_norvegicus
ENSG00000135372	NAT10	100	100.000	ENSRBIG00000028922	NAT10	100	98.733	Rhinopithecus_bieti
ENSG00000135372	NAT10	100	100.000	ENSRROG00000011811	NAT10	100	98.830	Rhinopithecus_roxellana
ENSG00000135372	NAT10	100	60.959	YNL132W	-	100	55.085	Saccharomyces_cerevisiae
ENSG00000135372	NAT10	100	99.310	ENSSBOG00000023643	NAT10	100	98.343	Saimiri_boliviensis_boliviensis
ENSG00000135372	NAT10	97	89.370	ENSSHAG00000003443	NAT10	100	89.674	Sarcophilus_harrisii
ENSG00000135372	NAT10	99	88.112	ENSSFOG00015015371	nat10	99	83.037	Scleropages_formosus
ENSG00000135372	NAT10	99	89.510	ENSSMAG00000010588	nat10	96	82.129	Scophthalmus_maximus
ENSG00000135372	NAT10	99	89.510	ENSSDUG00000021879	nat10	98	80.633	Seriola_dumerili
ENSG00000135372	NAT10	99	89.510	ENSSLDG00000005278	nat10	98	83.922	Seriola_lalandi_dorsalis
ENSG00000135372	NAT10	69	98.230	ENSSARG00000013457	NAT10	83	98.305	Sorex_araneus
ENSG00000135372	NAT10	100	93.103	ENSSPUG00000010599	-	99	86.404	Sphenodon_punctatus
ENSG00000135372	NAT10	99	88.811	ENSSPAG00000013867	nat10	98	81.238	Stegastes_partitus
ENSG00000135372	NAT10	100	98.621	ENSSSCG00000013304	NAT10	100	96.199	Sus_scrofa
ENSG00000135372	NAT10	100	95.862	ENSTGUG00000005638	-	99	87.377	Taeniopygia_guttata
ENSG00000135372	NAT10	99	90.210	ENSTRUG00000017064	nat10	96	81.627	Takifugu_rubripes
ENSG00000135372	NAT10	99	89.510	ENSTNIG00000016044	nat10	96	81.827	Tetraodon_nigroviridis
ENSG00000135372	NAT10	90	90.625	ENSTBEG00000010311	NAT10	84	97.222	Tupaia_belangeri
ENSG00000135372	NAT10	90	96.875	ENSTTRG00000007748	NAT10	92	93.915	Tursiops_truncatus
ENSG00000135372	NAT10	100	99.310	ENSUAMG00000010017	NAT10	99	95.374	Ursus_americanus
ENSG00000135372	NAT10	100	99.310	ENSUMAG00000018144	NAT10	99	95.374	Ursus_maritimus
ENSG00000135372	NAT10	100	98.621	ENSVVUG00000010185	NAT10	99	96.057	Vulpes_vulpes
ENSG00000135372	NAT10	100	87.586	ENSXETG00000003782	nat10	99	83.186	Xenopus_tropicalis
ENSG00000135372	NAT10	94	79.217	ENSXCOG00000016365	nat10	95	82.826	Xiphophorus_couchianus
ENSG00000135372	NAT10	99	87.413	ENSXMAG00000007325	nat10	98	80.634	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000154	rRNA modification	-	TAS	Process
GO:0000784	nuclear chromosome, telomeric region	19135898.	HDA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	25653167.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	11214970.	NAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005697	telomerase holoenzyme complex	18082603.	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	18082603.	IDA	Component
GO:0008080	N-acetyltransferase activity	25411247.25653167.	EXP	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0030496	midbody	-	IDA	Component
GO:0032211	negative regulation of telomere maintenance via telomerase	18082603.	IMP	Process
GO:0045727	positive regulation of translation	30449621.	IDA	Process
GO:0051391	tRNA acetylation	-	IEA	Process
GO:0070182	DNA polymerase binding	18082603.	IPI	Function
GO:1904812	rRNA acetylation involved in maturation of SSU-rRNA	21873635.	IBA	Process
GO:1990883	rRNA cytidine N-acetyltransferase activity	21873635.	IBA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24982245	GSK-3β-regulated N-acetyltransferase 10 is involved in colorectal cancer invasion.	Clin Cancer Res	2014 Sep 1	Zhang H	doi: 10.1158/1078-0432.CCR-13-3477

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr11	34141169	Missense_Mutation	novel	L891F	0.11	tRNA_bind_2
BLCA	chr11	34146090	Silent	novel	K992K	0.39
BLCA	chr11	34118234	Silent	NA	L204L	0.15
BLCA	chr11	34108323	Missense_Mutation	novel	G33V	0.27
BLCA	chr11	34135220	Missense_Mutation	NA	E653K	0.24
BLCA	chr11	34136707	Missense_Mutation	novel	L698F	0.29
BLCA	chr11	34132211	Missense_Mutation	novel	S536C	0.09
BLCA	chr11	34118428	Silent	novel	L235L	0.88
BLCA	chr11	34135267	Missense_Mutation	novel	Q668H	0.11
BLCA	chr11	34123817	Missense_Mutation	novel	E324K	0.28
BLCA	chr11	34124317	Nonsense_Mutation	novel	E342*	0.31
BLCA	chr11	34139239	Missense_Mutation	novel	D754N	0.36
BLCA	chr11	34108275	Missense_Mutation	novel	G17A	0.16
BLCA	chr11	34146146	Missense_Mutation	NA	R1011T	0.14
BLCA	chr11	34146156	Silent	novel	K1014K	0.22
BRCA	chr11	34118417	Missense_Mutation	novel	D232N	0.23
BRCA	chr11	34146137	Missense_Mutation	novel	L1008S	0.09
BRCA	chr11	34139397	Missense_Mutation	NA	R774L	0.56	tRNA_bind_2
BRCA	chr11	34112141	Missense_Mutation	novel	I97T	0.11
BRCA	chr11	34139425	Silent	NA	F783F	0.21
BRCA	chr11	34142347	Missense_Mutation	NA	E962K	0.22	tRNA_bind_2
BRCA	chr11	34143447	Missense_Mutation	NA	Y963C	0.19	tRNA_bind_2
BRCA	chr11	34139416	Silent	NA	S780S	0.43
BRCA	chr11	34115847	Missense_Mutation	novel	E174Q	0.08
BRCA	chr11	34132183	Nonsense_Mutation	novel	Q527*	0.05
BRCA	chr11	34131527	Missense_Mutation	novel	E506K	0.18
CESC	chr11	34140463	Missense_Mutation	novel	Y828C	0.41	tRNA_bind_2
CESC	chr11	34135220	Missense_Mutation	NA	E653K	0.41
CESC	chr11	34140572	Splice_Region	novel	S864S	0.12
CESC	chr11	34141812	Missense_Mutation	rs553463575	D936N	0.09	tRNA_bind_2
CESC	chr11	34134341	Missense_Mutation	NA	S586F	0.41
CESC	chr11	34136676	Missense_Mutation	rs527894514	R688Q	0.36
COAD	chr11	34140423	Missense_Mutation	rs755795306	A815T	0.09	tRNA_bind_2
COAD	chr11	34108293	Missense_Mutation	novel	R23I	0.34
COAD	chr11	34146311	3'UTR	novel		0.32
COAD	chr11	34141782	Missense_Mutation	novel	M926V	0.31	tRNA_bind_2
COAD	chr11	34136645	Missense_Mutation	NA	V678F	0.34
COAD	chr11	34127528	Silent	rs141428058	A391A	0.37
COAD	chr11	34130917	Missense_Mutation	rs148211973	T450M	0.12
COAD	chr11	34132198	Missense_Mutation	novel	L532F	0.25
COAD	chr11	34146159	Frame_Shift_Ins	rs773784521	*D1018Rfs19**	0.15
COAD	chr11	34122501	Missense_Mutation	novel	T275P	0.33
COAD	chr11	34118468	Missense_Mutation	novel	G249C	0.07
COAD	chr11	34132203	Silent	rs762435719	Y533Y	0.3
COAD	chr11	34146156	Missense_Mutation	NA	K1014N	0.09
COAD	chr11	34112082	Silent	novel	Q77Q	0.07
COAD	chr11	34140510	Missense_Mutation	NA	A844T	0.28	tRNA_bind_2
GBM	chr11	34142305	Missense_Mutation	novel	H948D	0.06	tRNA_bind_2
GBM	chr11	34141195	Missense_Mutation	rs765389946	R900H	0.1	tRNA_bind_2
GBM	chr11	34130875	Missense_Mutation	novel	A436D	0.09
GBM	chr11	34108317	Missense_Mutation	NA	D31A	0.1
HNSC	chr11	34118270	Missense_Mutation	novel	M216I	0.09
KIRC	chr11	34143491	In_Frame_Ins	novel	K978delinsSRKE	0.05
KIRP	chr11	34141147	Missense_Mutation	novel	I884N	0.35	tRNA_bind_2
LAML	chr11	34131511	Frame_Shift_Ins	novel	*L501Ifs3**	0.12
LGG	chr11	34118217	Missense_Mutation	rs748227063	V199I	0.45
LGG	chr11	34130866	Missense_Mutation	NA	Q433P	0.22
LGG	chr11	34141150	Frame_Shift_Ins	novel	*L886Afs33**	0.1	tRNA_bind_2
LGG	chr11	34139205	Silent	novel	G742G	0.09
LIHC	chr11	34113779	Frame_Shift_Del	novel	L146*	0.28
LIHC	chr11	34130872	Missense_Mutation	NA	S435N	0.28
LIHC	chr11	34115828	Silent	NA	V167V	0.29
LUAD	chr11	34122580	Missense_Mutation	rs201610017	A301V	0.46
LUAD	chr11	34118432	Nonsense_Mutation	NA	E237*	0.39
LUAD	chr11	34134571	Missense_Mutation	novel	H632Q	0.08
LUAD	chr11	34112104	Silent	novel	L85L	0.08
LUAD	chr11	34127543	Silent	rs771255449	P396P	0.19
LUAD	chr11	34108279	Silent	NA	V18V	0.26
LUAD	chr11	34140542	Frame_Shift_Del	NA	*D856Tfs36**	0.2	tRNA_bind_2
LUAD	chr11	34127471	Silent	novel	H372H	0.06
LUAD	chr11	34122581	Silent	novel	A301A	0.19
LUAD	chr11	34122582	Missense_Mutation	novel	V302L	0.17
LUAD	chr11	34133127	Silent	novel	V573V	0.38
LUAD	chr11	34139245	Missense_Mutation	NA	D756Y	0.16
LUAD	chr11	34146096	Silent	NA	R994R	0.24
LUAD	chr11	34122506	Silent	rs771936992	L276L	0.26
LUAD	chr11	34127598	Missense_Mutation	novel	G415C	0.08
LUAD	chr11	34132143	Silent	NA	D513D	0.14
LUAD	chr11	34118405	Missense_Mutation	NA	L228V	0.13
LUAD	chr11	34118255	Silent	NA	S211S	0.49
LUAD	chr11	34140531	Missense_Mutation	NA	L851V	0.2	tRNA_bind_2
LUSC	chr11	34124332	Missense_Mutation	NA	L347I	0.22
LUSC	chr11	34122550	Missense_Mutation	novel	S291F	0.34
LUSC	chr11	34141148	Silent	novel	I884I	0.08
LUSC	chr11	34146224	3'UTR	novel		0.71
LUSC	chr11	34130839	Missense_Mutation	NA	S424F	0.21
LUSC	chr11	34132145	Missense_Mutation	novel	T514I	0.17
LUSC	chr11	34108757	Missense_Mutation	novel	H42Y	0.2
OV	chr11	34132133	Missense_Mutation	NA	V510A	0.07
OV	chr11	34118191	Missense_Mutation	novel	S190C	0.07
OV	chr11	34135234	Silent	novel	P657P	0.04
OV	chr11	34135236	Frame_Shift_Ins	novel	*L659Sfs7**	0.03
OV	chr11	34133074	Frame_Shift_Del	novel	*L556Sfs36**	0.04
OV	chr11	34131491	Missense_Mutation	rs138988892	R494W	0.38
OV	chr11	34135225	Silent	novel	G654G	0.04
PAAD	chr11	34140563	Silent	rs374547624	A861A	0.17
PAAD	chr11	34140453	Missense_Mutation	novel	L825M	0.18	tRNA_bind_2
READ	chr11	34115820	Splice_Region	novel		0.11
READ	chr11	34112061	Missense_Mutation	novel	K70N	0.49
READ	chr11	34130917	Missense_Mutation	rs148211973	T450M	0.37
SARC	chr11	34135288	Silent	rs372918376	S675S	0.25
SKCM	chr11	34135278	Missense_Mutation	NA	T672I	0.1
SKCM	chr11	34108255	Silent	NA	I10I	0.11
SKCM	chr11	34123853	Nonsense_Mutation	NA	Q336*	0.45
SKCM	chr11	34122537	Missense_Mutation	novel	G287R	0.28
SKCM	chr11	34143464	Missense_Mutation	rs751116586	D969N	0.24	tRNA_bind_2
SKCM	chr11	34134343	Missense_Mutation	rs756436278	R587C	0.44
SKCM	chr11	34139277	Silent	rs113424951	A766A	0.2
SKCM	chr11	34112126	Missense_Mutation	NA	P92L	0.36
SKCM	chr11	34131403	Silent	NA	S464S	0.54
SKCM	chr11	34131418	Silent	NA	I469I	0.45
SKCM	chr11	34127540	Silent	NA	L395L	0.19
SKCM	chr11	34139469	Missense_Mutation	NA	R798K	0.21	tRNA_bind_2
SKCM	chr11	34141185	Missense_Mutation	novel	R897W	0.21	tRNA_bind_2
SKCM	chr11	34113839	Splice_Site	NA	X165_splice	0.71
SKCM	chr11	34131402	Missense_Mutation	NA	S464F	0.27
SKCM	chr11	34131407	Nonsense_Mutation	NA	Q466*	0.47
SKCM	chr11	34123811	Silent	NA	L322L	0.09
SKCM	chr11	34113814	Silent	novel	L157L	0.28
SKCM	chr11	34137003	Missense_Mutation	NA	P730S	0.27
SKCM	chr11	34108249	Silent	rs748833226	N8N	0.72
SKCM	chr11	34134585	Missense_Mutation	NA	G637E	0.27
STAD	chr11	34124378	Missense_Mutation	NA	R362Q	0.23
STAD	chr11	34143477	Missense_Mutation	NA	N973S	0.24	tRNA_bind_2
STAD	chr11	34139270	Missense_Mutation	NA	L764P	0.05	tRNA_bind_2
STAD	chr11	34136760	Frame_Shift_Del	novel	*R718Gfs16**	0.26
STAD	chr11	34141799	Silent	NA	K931K	0.35
STAD	chr11	34122484	Missense_Mutation	NA	E269V	0.09
STAD	chr11	34146230	3'UTR	novel		0.58
STAD	chr11	34112207	Missense_Mutation	NA	G119A	0.17
STAD	chr11	34108235	Frame_Shift_Del	novel	*K5Rfs14**	0.21
STAD	chr11	34115823	Missense_Mutation	novel	D166N	0.08
STAD	chr11	34108750	Missense_Mutation	NA	I39M	0.12
UCEC	chr11	34113797	Missense_Mutation	rs149812318	R152W	0.43
UCEC	chr11	34133092	Missense_Mutation	NA	P562S	0.31
UCEC	chr11	34124377	Nonsense_Mutation	rs751108174	R362*	0.27
UCEC	chr11	34133118	Silent	NA	L570L	0.32
UCEC	chr11	34139475	Frame_Shift_Ins	novel	*K802Efs20**	0.09	tRNA_bind_2
UCEC	chr11	34108319	Nonsense_Mutation	NA	R32*	0.32
UCEC	chr11	34122500	Missense_Mutation	NA	K274N	0.46
UCEC	chr11	34141730	Silent	novel	E908E	0.04
UCEC	chr11	34146146	Missense_Mutation	NA	R1011I	0.23
UCEC	chr11	34122586	Missense_Mutation	NA	A303V	0.17
UCEC	chr11	34132123	Splice_Site	novel	X507_splice	0.09
UCEC	chr11	34136667	Missense_Mutation	NA	I685T	0.12
UCEC	chr11	34139203	Missense_Mutation	rs756565845	G742R	0.17
UCEC	chr11	34146311	3'UTR	novel		0.31
UCEC	chr11	34140502	Missense_Mutation	novel	M841T	0.36	tRNA_bind_2
UCEC	chr11	34112071	Nonsense_Mutation	rs538386063	R74*	0.31
UCEC	chr11	34143505	Silent	rs147462500	N982N	0.39
UCEC	chr11	34131531	Missense_Mutation	novel	L507P	0.34
UCEC	chr11	34108789	Silent	rs751404505	R52R	0.19
UCEC	chr11	34141744	Missense_Mutation	NA	A913D	0.31	tRNA_bind_2
UCEC	chr11	34139212	Missense_Mutation	NA	S745A	0.38
UCEC	chr11	34124333	Missense_Mutation	novel	L347R	0.36
UCEC	chr11	34108821	Missense_Mutation	NA	L63P	0.07
UCEC	chr11	34115833	Missense_Mutation	novel	S169F	0.3
UCEC	chr11	34132211	Missense_Mutation	novel	S536Y	0.4
UCEC	chr11	34112057	Missense_Mutation	novel	R69Q	0.42
UCEC	chr11	34115855	Silent	novel	H176H	0.34
UCEC	chr11	34115842	Missense_Mutation	novel	R172I	0.46
UCEC	chr11	34108250	Nonsense_Mutation	rs756936856	R9*	0.37
UCEC	chr11	34112205	Silent	rs569421809	F118F	0.09
UCEC	chr11	34118259	Missense_Mutation	rs200281086	V213I	0.36
UCEC	chr11	34132204	Missense_Mutation	rs774400250	V534M	0.29
UCEC	chr11	34143480	Missense_Mutation	novel	E974G	0.25	tRNA_bind_2
UCEC	chr11	34136665	Silent	rs771116004	V684V	0.24
UCEC	chr11	34146204	3'UTR	novel		0.27
UCEC	chr11	34127571	Missense_Mutation	novel	L406I	0.24
UCEC	chr11	34112159	Missense_Mutation	rs770413727	R103H	0.34
UCEC	chr11	34122482	Silent	rs142291579	I268I	0.08
UCEC	chr11	34136723	Missense_Mutation	rs746905450	E704K	0.35
UCEC	chr11	34146182	Missense_Mutation	NA	R1023Q	0.46
UCEC	chr11	34143501	Missense_Mutation	rs183448235	P981L	0.24
UCEC	chr11	34112071	Nonsense_Mutation	rs538386063	R74*	0.13
UCEC	chr11	34118227	Missense_Mutation	NA	D202G	0.18
UCEC	chr11	34123823	Missense_Mutation	novel	V326I	0.38
UCEC	chr11	34134553	Silent	novel	V626V	0.15
UCEC	chr11	34139204	Missense_Mutation	novel	G742E	0.15
UCEC	chr11	34146107	Missense_Mutation	novel	A998V	0.63
UCEC	chr11	34137012	Silent	rs747249893	L733L	0.36
UCEC	chr11	34108286	Missense_Mutation	rs143567201	R21W	0.25
UCEC	chr11	34133055	Silent	rs577046723	S549S	0.48
UCEC	chr11	34113830	Missense_Mutation	novel	V163M	0.36
UCEC	chr11	34108293	Missense_Mutation	novel	R23I	0.31
UCEC	chr11	34108788	Missense_Mutation	rs758062189	R52Q	0.5
UCEC	chr11	34112072	Missense_Mutation	novel	R74Q	0.27
UCEC	chr11	34130918	Silent	novel	T450T	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.0784	0.084381
ESCA	AMP	0.1902	0.018342
TGCT	DEL	0.58	0.21504

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0091	Kaplan-Meier Survival Analysis
HNSC	0.00035	Kaplan-Meier Survival Analysis
KIRP	0.0035	Kaplan-Meier Survival Analysis
PAAD	0.017	Kaplan-Meier Survival Analysis
PCPG	0.018	Kaplan-Meier Survival Analysis
READ	0.021	Kaplan-Meier Survival Analysis
KICH	0.0038	Kaplan-Meier Survival Analysis
GBM	0.011	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
UVM	0.012	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742