EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000135482 (Gene tree)
Gene ID: 84872
Gene Symbol: ZC3H10
Alias: FLJ14451|ZC3HDC10
Full Name: zinc finger CCCH-type containing 10
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 9,356 bases
Position: chr12:56,118,159-56,127,514
Accession: 25893
RBP type: canonical RBP
Summary: (Zinc Finger CCCH-Type Containing 10) is a Protein Coding gene. An important paralog of this gene is MBNL3.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000257940	zf-CCCH	PF00642.24	4.8e-11	1	2
ENSP00000257940	zf-CCCH	PF00642.24	4.8e-11	2	2
ENSP00000450122	zf-CCCH	PF00642.24	8.8e-05	1	1
ENSP00000448881	zf-CCCH	PF00642.24	0.00016	1	1
ENSP00000257940	zf-CCCH_2	PF14608.6	1.1e-08	1	3
ENSP00000257940	zf-CCCH_2	PF14608.6	1.1e-08	2	3
ENSP00000257940	zf-CCCH_2	PF14608.6	1.1e-08	3	3

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000549973	ZC3H10-203	590	-	-	- (aa)	-	-
ENST00000546903	ZC3H10-202	743	-	ENSP00000448881	88 (aa)	-	F8VYY3
ENST00000257940	ZC3H10-201	7228	-	ENSP00000257940	434 (aa)	-	Q96K80
ENST00000552345	ZC3H10-205	552	-	ENSP00000450122	79 (aa)	-	F8VQT2
ENST00000551880	ZC3H10-204	1019	-	ENSP00000448309	45 (aa)	-	F8VSG0

Gene Model

Click here to download ENSG00000135482's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000135482	Scleroderma, Systemic	6E-8	21779181

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000135482	rs11171747	12	56124624	?	Systemic sclerosis	21779181	[1.14-1.33]	1.23	EFO_0000717

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135482's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000135482	ZC3H10	82	75.463	ENSAPOG00000013862	zc3h10	75	75.926	Acanthochromis_polyacanthus
ENSG00000135482	ZC3H10	100	97.931	ENSAMEG00000019365	ZC3H10	100	97.931	Ailuropoda_melanoleuca
ENSG00000135482	ZC3H10	82	75.000	ENSACIG00000022311	zc3h10	93	60.588	Amphilophus_citrinellus
ENSG00000135482	ZC3H10	82	75.463	ENSAOCG00000021782	zc3h10	75	75.926	Amphiprion_ocellaris
ENSG00000135482	ZC3H10	82	75.463	ENSAPEG00000010972	zc3h10	75	75.926	Amphiprion_percula
ENSG00000135482	ZC3H10	83	75.000	ENSATEG00000024754	zc3h10	61	77.344	Anabas_testudineus
ENSG00000135482	ZC3H10	100	74.253	ENSACAG00000005020	ZC3H10	94	79.494	Anolis_carolinensis
ENSG00000135482	ZC3H10	100	98.618	ENSANAG00000004774	ZC3H10	100	98.618	Aotus_nancymaae
ENSG00000135482	ZC3H10	82	76.562	ENSACLG00000001913	zc3h10	86	46.998	Astatotilapia_calliptera
ENSG00000135482	ZC3H10	85	72.917	ENSAMXG00000000266	zc3h10	60	76.744	Astyanax_mexicanus
ENSG00000135482	ZC3H10	100	97.241	ENSBTAG00000009542	ZC3H10	100	97.241	Bos_taurus
ENSG00000135482	ZC3H10	100	99.078	ENSCJAG00000045638	ZC3H10	100	99.078	Callithrix_jacchus
ENSG00000135482	ZC3H10	100	97.011	ENSCAFG00000000104	ZC3H10	100	97.011	Canis_familiaris
ENSG00000135482	ZC3H10	100	97.011	ENSCAFG00020025996	ZC3H10	100	97.011	Canis_lupus_dingo
ENSG00000135482	ZC3H10	100	97.701	ENSCHIG00000003359	ZC3H10	100	97.701	Capra_hircus
ENSG00000135482	ZC3H10	100	98.864	ENSTSYG00000014379	ZC3H10	100	98.621	Carlito_syrichta
ENSG00000135482	ZC3H10	100	95.455	ENSCAPG00000002936	ZC3H10	100	96.992	Cavia_aperea
ENSG00000135482	ZC3H10	100	97.471	ENSCPOG00000032639	ZC3H10	100	97.471	Cavia_porcellus
ENSG00000135482	ZC3H10	100	98.387	ENSCCAG00000020214	-	100	98.387	Cebus_capucinus
ENSG00000135482	ZC3H10	100	99.770	ENSCATG00000012691	ZC3H10	100	99.770	Cercocebus_atys
ENSG00000135482	ZC3H10	100	97.931	ENSCLAG00000011346	ZC3H10	100	97.931	Chinchilla_lanigera
ENSG00000135482	ZC3H10	100	99.539	ENSCSAG00000018893	ZC3H10	100	99.539	Chlorocebus_sabaeus
ENSG00000135482	ZC3H10	100	73.733	ENSCPBG00000012828	ZC3H10	100	74.424	Chrysemys_picta_bellii
ENSG00000135482	ZC3H10	56	44.231	ENSCSAVG00000001429	-	61	46.715	Ciona_savignyi
ENSG00000135482	ZC3H10	100	99.770	ENSCANG00000007357	ZC3H10	100	99.770	Colobus_angolensis_palliatus
ENSG00000135482	ZC3H10	100	97.011	ENSCGRG00001004310	Zc3h10	100	97.011	Cricetulus_griseus_chok1gshd
ENSG00000135482	ZC3H10	100	97.011	ENSCGRG00000015981	Zc3h10	100	97.011	Cricetulus_griseus_crigri
ENSG00000135482	ZC3H10	92	69.333	ENSCSEG00000003687	zc3h10	86	46.516	Cynoglossus_semilaevis
ENSG00000135482	ZC3H10	89	75.397	ENSCVAG00000001548	zc3h10	86	45.625	Cyprinodon_variegatus
ENSG00000135482	ZC3H10	85	73.793	ENSDARG00000030335	zc3h10	87	77.519	Danio_rerio
ENSG00000135482	ZC3H10	100	97.727	ENSDNOG00000040571	ZC3H10	100	97.701	Dasypus_novemcinctus
ENSG00000135482	ZC3H10	100	96.552	ENSDORG00000001081	Zc3h10	100	96.552	Dipodomys_ordii
ENSG00000135482	ZC3H10	100	97.931	ENSEASG00005003533	ZC3H10	100	97.931	Equus_asinus_asinus
ENSG00000135482	ZC3H10	100	98.161	ENSECAG00000013003	ZC3H10	100	98.161	Equus_caballus
ENSG00000135482	ZC3H10	91	59.204	ENSELUG00000019470	zc3h10	99	80.000	Esox_lucius
ENSG00000135482	ZC3H10	100	98.161	ENSFDAG00000012558	ZC3H10	100	98.161	Fukomys_damarensis
ENSG00000135482	ZC3H10	86	75.701	ENSFHEG00000021836	zc3h10	94	61.143	Fundulus_heteroclitus
ENSG00000135482	ZC3H10	50	81.818	ENSGMOG00000008567	zc3h10	52	74.797	Gadus_morhua
ENSG00000135482	ZC3H10	100	74.483	ENSGALG00000037941	ZC3H10	100	74.943	Gallus_gallus
ENSG00000135482	ZC3H10	89	75.000	ENSGAFG00000002137	zc3h10	81	46.331	Gambusia_affinis
ENSG00000135482	ZC3H10	91	66.000	ENSGACG00000000638	zc3h10	90	65.087	Gasterosteus_aculeatus
ENSG00000135482	ZC3H10	100	73.963	ENSGAGG00000020590	ZC3H10	100	74.654	Gopherus_agassizii
ENSG00000135482	ZC3H10	100	99.539	ENSGGOG00000039636	ZC3H10	100	99.539	Gorilla_gorilla
ENSG00000135482	ZC3H10	100	97.701	ENSHGLG00000015956	ZC3H10	100	97.701	Heterocephalus_glaber_female
ENSG00000135482	ZC3H10	100	97.701	ENSHGLG00100013005	ZC3H10	100	97.701	Heterocephalus_glaber_male
ENSG00000135482	ZC3H10	83	73.023	ENSHCOG00000020331	zc3h10	99	57.286	Hippocampus_comes
ENSG00000135482	ZC3H10	91	58.246	ENSIPUG00000001697	zc3h10	85	47.189	Ictalurus_punctatus
ENSG00000135482	ZC3H10	100	97.701	ENSSTOG00000007753	ZC3H10	100	97.701	Ictidomys_tridecemlineatus
ENSG00000135482	ZC3H10	100	96.782	ENSJJAG00000001726	Zc3h10	100	96.782	Jaculus_jaculus
ENSG00000135482	ZC3H10	79	76.852	ENSKMAG00000017905	zc3h10	85	46.973	Kryptolebias_marmoratus
ENSG00000135482	ZC3H10	79	77.344	ENSLBEG00000018281	zc3h10	59	77.344	Labrus_bergylta
ENSG00000135482	ZC3H10	100	65.826	ENSLACG00000002390	ZC3H10	100	63.946	Latimeria_chalumnae
ENSG00000135482	ZC3H10	100	97.011	ENSLAFG00000014817	ZC3H10	100	97.011	Loxodonta_africana
ENSG00000135482	ZC3H10	100	99.770	ENSMFAG00000027256	ZC3H10	100	99.770	Macaca_fascicularis
ENSG00000135482	ZC3H10	100	99.770	ENSMMUG00000021084	ZC3H10	100	99.770	Macaca_mulatta
ENSG00000135482	ZC3H10	100	99.770	ENSMNEG00000025282	ZC3H10	100	99.770	Macaca_nemestrina
ENSG00000135482	ZC3H10	100	99.770	ENSMLEG00000027930	ZC3H10	100	99.770	Mandrillus_leucophaeus
ENSG00000135482	ZC3H10	79	76.190	ENSMAMG00000003284	zc3h10	61	76.389	Mastacembelus_armatus
ENSG00000135482	ZC3H10	100	97.241	ENSMAUG00000008505	Zc3h10	100	97.241	Mesocricetus_auratus
ENSG00000135482	ZC3H10	100	95.172	ENSMOCG00000019869	Zc3h10	100	95.172	Microtus_ochrogaster
ENSG00000135482	ZC3H10	83	74.627	ENSMMOG00000021874	zc3h10	86	47.205	Mola_mola
ENSG00000135482	ZC3H10	85	75.576	ENSMALG00000016443	zc3h10	61	75.781	Monopterus_albus
ENSG00000135482	ZC3H10	100	97.727	MGP_CAROLIEiJ_G0015942	Zc3h10	100	97.241	Mus_caroli
ENSG00000135482	ZC3H10	100	97.727	ENSMUSG00000039810	Zc3h10	100	98.519	Mus_musculus
ENSG00000135482	ZC3H10	100	97.011	MGP_PahariEiJ_G0031142	Zc3h10	100	97.011	Mus_pahari
ENSG00000135482	ZC3H10	100	96.552	MGP_SPRETEiJ_G0016767	Zc3h10	100	96.552	Mus_spretus
ENSG00000135482	ZC3H10	100	97.727	ENSMPUG00000018496	ZC3H10	100	97.471	Mustela_putorius_furo
ENSG00000135482	ZC3H10	100	96.591	ENSMLUG00000006564	ZC3H10	100	92.644	Myotis_lucifugus
ENSG00000135482	ZC3H10	100	97.241	ENSNGAG00000011848	Zc3h10	100	97.241	Nannospalax_galili
ENSG00000135482	ZC3H10	79	76.562	ENSNBRG00000020931	zc3h10	86	46.791	Neolamprologus_brichardi
ENSG00000135482	ZC3H10	100	89.773	ENSMEUG00000001222	ZC3H10	100	88.330	Notamacropus_eugenii
ENSG00000135482	ZC3H10	100	97.701	ENSODEG00000007942	ZC3H10	100	97.701	Octodon_degus
ENSG00000135482	ZC3H10	100	64.732	ENSONIG00000019154	zc3h10	90	65.517	Oreochromis_niloticus
ENSG00000135482	ZC3H10	100	96.789	ENSOCUG00000017349	ZC3H10	100	96.789	Oryctolagus_cuniculus
ENSG00000135482	ZC3H10	97	57.143	ENSORLG00000014596	zc3h10	87	46.347	Oryzias_latipes
ENSG00000135482	ZC3H10	97	56.944	ENSORLG00020000559	zc3h10	87	46.138	Oryzias_latipes_hni
ENSG00000135482	ZC3H10	97	56.944	ENSORLG00015014077	zc3h10	87	46.347	Oryzias_latipes_hsok
ENSG00000135482	ZC3H10	100	54.463	ENSOMEG00000023135	zc3h10	87	46.555	Oryzias_melastigma
ENSG00000135482	ZC3H10	100	96.092	ENSOGAG00000030676	ZC3H10	100	96.092	Otolemur_garnettii
ENSG00000135482	ZC3H10	100	96.591	ENSOARG00000010330	ZC3H10	100	94.483	Ovis_aries
ENSG00000135482	ZC3H10	100	99.770	ENSPPAG00000023790	ZC3H10	100	99.770	Pan_paniscus
ENSG00000135482	ZC3H10	100	97.701	ENSPTIG00000006237	ZC3H10	100	97.701	Panthera_tigris_altaica
ENSG00000135482	ZC3H10	100	99.770	ENSPTRG00000005078	ZC3H10	100	99.770	Pan_troglodytes
ENSG00000135482	ZC3H10	100	99.770	ENSPANG00000029620	ZC3H10	100	99.770	Papio_anubis
ENSG00000135482	ZC3H10	83	74.299	ENSPKIG00000007158	zc3h10	68	71.889	Paramormyrops_kingsleyae
ENSG00000135482	ZC3H10	99	65.517	ENSPSIG00000000811	ZC3H10	87	71.159	Pelodiscus_sinensis
ENSG00000135482	ZC3H10	99	62.069	ENSPMGG00000010570	zc3h10	92	64.078	Periophthalmus_magnuspinnatus
ENSG00000135482	ZC3H10	100	96.782	ENSPEMG00000008278	Zc3h10	100	96.782	Peromyscus_maniculatus_bairdii
ENSG00000135482	ZC3H10	100	88.636	ENSPCIG00000007018	ZC3H10	100	88.128	Phascolarctos_cinereus
ENSG00000135482	ZC3H10	89	74.219	ENSPFOG00000006164	zc3h10	85	45.979	Poecilia_formosa
ENSG00000135482	ZC3H10	91	64.599	ENSPLAG00000001248	zc3h10	85	45.979	Poecilia_latipinna
ENSG00000135482	ZC3H10	89	74.219	ENSPMEG00000002660	zc3h10	85	45.155	Poecilia_mexicana
ENSG00000135482	ZC3H10	89	74.219	ENSPREG00000015323	zc3h10	85	46.186	Poecilia_reticulata
ENSG00000135482	ZC3H10	100	96.591	ENSPPYG00000004644	ZC3H10	100	80.184	Pongo_abelii
ENSG00000135482	ZC3H10	100	95.172	ENSPCAG00000005636	ZC3H10	100	95.632	Procavia_capensis
ENSG00000135482	ZC3H10	100	96.552	ENSPCOG00000012389	ZC3H10	100	96.552	Propithecus_coquereli
ENSG00000135482	ZC3H10	100	96.782	ENSPVAG00000007566	ZC3H10	100	96.782	Pteropus_vampyrus
ENSG00000135482	ZC3H10	79	76.562	ENSPNYG00000021193	zc3h10	86	46.998	Pundamilia_nyererei
ENSG00000135482	ZC3H10	79	75.969	ENSPNAG00000013796	zc3h10	60	75.969	Pygocentrus_nattereri
ENSG00000135482	ZC3H10	100	96.322	ENSRNOG00000040281	Zc3h10	100	96.322	Rattus_norvegicus
ENSG00000135482	ZC3H10	100	99.539	ENSRBIG00000019615	ZC3H10	100	99.539	Rhinopithecus_bieti
ENSG00000135482	ZC3H10	100	99.539	ENSRROG00000013225	ZC3H10	100	99.539	Rhinopithecus_roxellana
ENSG00000135482	ZC3H10	100	99.078	ENSSBOG00000019876	ZC3H10	100	99.078	Saimiri_boliviensis_boliviensis
ENSG00000135482	ZC3H10	100	88.636	ENSSHAG00000005568	ZC3H10	100	87.643	Sarcophilus_harrisii
ENSG00000135482	ZC3H10	79	78.571	ENSSFOG00015015320	zc3h10	84	46.421	Scleropages_formosus
ENSG00000135482	ZC3H10	79	75.000	ENSSMAG00000003388	zc3h10	87	44.444	Scophthalmus_maximus
ENSG00000135482	ZC3H10	79	75.781	ENSSDUG00000006067	zc3h10	61	75.781	Seriola_dumerili
ENSG00000135482	ZC3H10	79	75.781	ENSSLDG00000002721	zc3h10	61	75.781	Seriola_lalandi_dorsalis
ENSG00000135482	ZC3H10	100	95.455	ENSSARG00000007208	ZC3H10	75	97.973	Sorex_araneus
ENSG00000135482	ZC3H10	92	76.750	ENSSPUG00000014715	ZC3H10	94	78.030	Sphenodon_punctatus
ENSG00000135482	ZC3H10	84	75.463	ENSSPAG00000001210	zc3h10	61	76.562	Stegastes_partitus
ENSG00000135482	ZC3H10	100	97.931	ENSSSCG00000033568	ZC3H10	100	97.931	Sus_scrofa
ENSG00000135482	ZC3H10	87	76.744	ENSTRUG00000009733	zc3h10	86	46.862	Takifugu_rubripes
ENSG00000135482	ZC3H10	91	66.586	ENSTNIG00000014558	zc3h10	95	66.908	Tetraodon_nigroviridis
ENSG00000135482	ZC3H10	100	97.727	ENSTTRG00000016415	ZC3H10	100	97.241	Tursiops_truncatus
ENSG00000135482	ZC3H10	100	97.727	ENSUAMG00000010526	ZC3H10	100	92.810	Ursus_americanus
ENSG00000135482	ZC3H10	100	97.931	ENSUMAG00000016780	ZC3H10	100	97.931	Ursus_maritimus
ENSG00000135482	ZC3H10	100	97.727	ENSVPAG00000009524	ZC3H10	100	97.471	Vicugna_pacos
ENSG00000135482	ZC3H10	100	97.011	ENSVVUG00000021999	ZC3H10	100	97.011	Vulpes_vulpes
ENSG00000135482	ZC3H10	94	63.953	ENSXETG00000009476	zc3h10	95	65.144	Xenopus_tropicalis
ENSG00000135482	ZC3H10	87	75.000	ENSXCOG00000018650	zc3h10	85	46.488	Xiphophorus_couchianus
ENSG00000135482	ZC3H10	79	75.463	ENSXMAG00000002294	zc3h10	85	45.436	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005515	protein binding	16189514.16713569.19060904.23275563.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0010608	posttranscriptional regulation of gene expression	28431233.	IDA	Process
GO:0035198	miRNA binding	28431233.	IDA	Function
GO:0046872	metal ion binding	-	IEA	Function
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	28431233.	IDA	Process