EuRBPDB

Description

Ensembl ID: ENSG00000135720 (Gene tree)
Gene ID: 1783
Gene Symbol: DYNC1LI2
Alias: DNCLI2
Full Name: dynein cytoplasmic 1 light intermediate chain 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 30,906 bases
Position: chr16:66,720,893-66,751,798
Accession: 2966
RBP type: non-canonical RBP
Summary: Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins.[supplied by OMIM, Mar 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000567499	DYNC1LI2-211	3994	-	-	- (aa)	-	-
ENST00000568180	DYNC1LI2-212	573	-	ENSP00000457464	56 (aa)	-	H3BU48
ENST00000258198	DYNC1LI2-201	4515	XM_017023008	ENSP00000258198	492 (aa)	XP_016878497	O43237
ENST00000564090	DYNC1LI2-206	566	-	ENSP00000463124	40 (aa)	-	J3QKK5
ENST00000570201	DYNC1LI2-215	292	-	-	- (aa)	-	-
ENST00000565532	DYNC1LI2-209	744	-	-	- (aa)	-	-
ENST00000569320	DYNC1LI2-214	641	-	ENSP00000462017	167 (aa)	-	J3KRI4
ENST00000564559	DYNC1LI2-207	563	-	ENSP00000462224	92 (aa)	-	J3KRZ2
ENST00000443351	DYNC1LI2-203	1502	-	ENSP00000394289	415 (aa)	-	O43237
ENST00000564833	DYNC1LI2-208	727	-	-	- (aa)	-	-
ENST00000566150	DYNC1LI2-210	568	-	ENSP00000457707	186 (aa)	-	H3BUM4
ENST00000561727	DYNC1LI2-204	502	-	-	- (aa)	-	-
ENST00000440564	DYNC1LI2-202	1145	-	ENSP00000408566	271 (aa)	-	B4E2E0
ENST00000563628	DYNC1LI2-205	355	-	ENSP00000462434	49 (aa)	-	J3KSD2
ENST00000568453	DYNC1LI2-213	571	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa04145	Phagosome	KEGG
hsa04962	Vasopressin-regulated water reabsorption	KEGG
hsa05132	Salmonella infection	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000135720	rs146550789	16	66747137	?	Systolic blood pressure	30595370			EFO_0006335

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000135720	DYNC1LI2	93	73.611	ENSG00000144635	DYNC1LI1	98	62.622	Homo_sapiens
ENSG00000135720	DYNC1LI2	100	100.000	ENSMUSG00000035770	Dync1li2	100	96.951	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000226	microtubule cytoskeleton organization	21873635.	IBA	Process
GO:0000776	kinetochore	-	IEA	Component
GO:0003777	microtubule motor activity	-	IEA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005764	lysosome	-	IEA	Component
GO:0005770	late endosome	-	IEA	Component
GO:0005813	centrosome	21873635.	IBA	Component
GO:0005813	centrosome	21399614.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005868	cytoplasmic dynein complex	21873635.	IBA	Component
GO:0005874	microtubule	-	IEA	Component
GO:0006888	ER to Golgi vesicle-mediated transport	-	TAS	Process
GO:0007018	microtubule-based movement	21873635.	IBA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	-	TAS	Process
GO:0045504	dynein heavy chain binding	21873635.	IBA	Function
GO:0051260	protein homooligomerization	-	IEA	Process
GO:0051642	centrosome localization	-	IEA	Process
GO:1990090	cellular response to nerve growth factor stimulus	-	IEA	Process