EuRBPDB

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  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • GWAS
  • PPI
  • Gene Ontology
Description
Ensembl ID
ENSG00000135837 (Gene tree)
Gene ID
9857
Gene Symbol
CEP350
Alias
KIAA0480|CAP350
Full Name
centrosomal protein 350
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Plus strand
Length
160,143 bases
Position
chr1:179,954,738-180,114,880
Accession
24238
RBP type
non-canonical RBP
Summary
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000429851CEP350-2056096-ENSP000004124601292 (aa)-H0Y7F7
ENST00000490141CEP350-2093549--- (aa)--
ENST00000367607CEP350-20213491XM_011510191ENSP000003565793117 (aa)XP_011508493Q5VT06
ENST00000496440CEP350-211765--- (aa)--
ENST00000437245CEP350-206408-ENSP00000409395110 (aa)-Q5T2X5
ENST00000417046CEP350-2032724-ENSP00000401608581 (aa)-Q5T2X4
ENST00000418229CEP350-204992-ENSP00000407044331 (aa)-H0Y6Q4
ENST00000484356CEP350-207524--- (aa)--
ENST00000357434CEP350-201392-ENSP00000350016130 (aa)-A2A4F6
ENST00000490047CEP350-208434-ENSP0000043291057 (aa)-H0YD38
ENST00000491495CEP350-2101059-ENSP00000435808242 (aa)-E9PIK0
Gene Model
Click here to download ENSG00000135837's gene model file
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000135837rs66922191180020449?Mean corpuscular hemoglobin30595370EFO_0004527
ENSG00000135837rs66922191180020449CSmoking initiation30617275[0.01-0.041] unit decrease (replication)0.0257EFO_0005670
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135837's network

* RBP PPI network refers to all genes directly bind to RBP
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0005515protein binding25134987.25764135.28428259.28625565.28659385.IPIFunction
GO:0005634nucleus-IEAComponent
GO:0005813centrosome21399614.IDAComponent
GO:0005814centriole28625565.IDAComponent
GO:0005819spindle-IEAComponent
GO:0008017microtubule binding-IEAFunction
GO:0016020membrane19946888.HDAComponent
GO:0034453microtubule anchoring-IEAProcess
GO:0042995cell projection-IEAComponent

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