EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000135930 (Gene tree)
Gene ID: 9470
Gene Symbol: EIF4E2
Alias: IF4e|4EHP|EIF4EL3
Full Name: eukaryotic translation initiation factor 4E family member 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 33,594 bases
Position: chr2:232,550,052-232,583,645
Accession: 3293
RBP type: canonical RBP
Summary: (Eukaryotic Translation Initiation Factor 4E Family Member 2) is a Protein Coding gene. Among its related pathways are Regulation of lipid metabolism Insulin signaling-generic cascades and mTOR signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding. An important paralog of this gene is EIF4E.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000390904	IF4E	PF01652.18	1.5e-59	1	1
ENSP00000387336	IF4E	PF01652.18	2e-59	1	1
ENSP00000386876	IF4E	PF01652.18	2e-59	1	1
ENSP00000386996	IF4E	PF01652.18	2e-59	1	1
ENSP00000258416	IF4E	PF01652.18	2.3e-59	1	1
ENSP00000387328	IF4E	PF01652.18	8.4e-49	1	1
ENSP00000386983	IF4E	PF01652.18	8.5e-49	1	1
ENSP00000386424	IF4E	PF01652.18	1e-48	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22678294	An oxygen-regulated switch in the protein synthesis machinery.	Nature	2012 May 6	Uniacke J	doi: 10.1038/nature11055.
24622240	Microarray meta-analysis of RNA-binding protein functions in alternative polyadenylation.	PLoS One	2014 Mar 12	Hu W	doi: 10.1371/journal.pone.0090774

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000409167	EIF4E2-203	1372	-	ENSP00000387328	188 (aa)	-	B4E1E4
ENST00000258416	EIF4E2-201	1604	-	ENSP00000258416	245 (aa)	-	O60573
ENST00000498242	EIF4E2-214	1110	-	-	- (aa)	-	-
ENST00000409322	EIF4E2-204	797	-	ENSP00000386424	200 (aa)	-	B8ZZL3
ENST00000409495	EIF4E2-206	1014	-	ENSP00000386876	233 (aa)	-	B9A044
ENST00000463074	EIF4E2-211	252	-	-	- (aa)	-	-
ENST00000409514	EIF4E2-207	3525	-	ENSP00000387336	236 (aa)	-	B8ZZ50
ENST00000444113	EIF4E2-208	571	-	ENSP00000389578	121 (aa)	-	H7BZH2
ENST00000409394	EIF4E2-205	604	-	ENSP00000386983	189 (aa)	-	B9A023
ENST00000478878	EIF4E2-212	268	-	-	- (aa)	-	-
ENST00000454501	EIF4E2-209	1048	-	ENSP00000390904	213 (aa)	-	C9JEL3
ENST00000459714	EIF4E2-210	575	-	-	- (aa)	-	-
ENST00000479834	EIF4E2-213	681	-	-	- (aa)	-	-
ENST00000409098	EIF4E2-202	3448	-	ENSP00000386996	234 (aa)	-	O60573

Gene Model

Click here to download ENSG00000135930's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa01521	EGFR tyrosine kinase inhibitor resistance	KEGG
hsa03013	RNA transport	KEGG
hsa04066	HIF-1 signaling pathway	KEGG
hsa04150	mTOR signaling pathway	KEGG
hsa04151	PI3K-Akt signaling pathway	KEGG
hsa04211	Longevity regulating pathway	KEGG
hsa04910	Insulin signaling pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000135930	Echocardiography	4.4172390052624E-6	17903301
ENSG00000135930	Platelet Function Tests	8.5600000E-006	-
ENSG00000135930	Carcinoma, Non-Small-Cell Lung	8E-8	21079520
ENSG00000135930	Body Height	1E-17	25282103

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000135930	rs1656402	2	232561816	?	Non-small cell lung cancer (survival)	21079520	[1.49-3.85] (AG)	2.38	EFO_0003060
ENSG00000135930	rs13393800	2	232577381	A	Height	25282103	[0.021-0.033] unit increase	0.027	EFO_0004339
ENSG00000135930	rs74453786	2	232576992	?	Lung function (FVC)	30595370			EFO_0004312

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135930's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000135930	EIF4E2	84	34.574	ENSG00000175766	EIF4E1B	93	31.602
ENSG00000135930	EIF4E2	81	32.597	ENSG00000163412	EIF4E3	89	41.026
ENSG00000135930	EIF4E2	78	34.503	ENSG00000151247	EIF4E	92	32.857

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000135930	EIF4E2	99	89.831	ENSAPOG00000024218	eif4e2rs1	99	89.831	Acanthochromis_polyacanthus
ENSG00000135930	EIF4E2	100	73.936	ENSAMEG00000010405	-	100	77.174	Ailuropoda_melanoleuca
ENSG00000135930	EIF4E2	100	98.776	ENSAMEG00000016456	-	100	98.776	Ailuropoda_melanoleuca
ENSG00000135930	EIF4E2	99	85.656	ENSACIG00000008514	eif4e2rs1	99	85.656	Amphilophus_citrinellus
ENSG00000135930	EIF4E2	97	89.868	ENSAOCG00000012215	eif4e2rs1	97	89.868	Amphiprion_ocellaris
ENSG00000135930	EIF4E2	97	89.868	ENSAPEG00000010529	eif4e2rs1	97	89.868	Amphiprion_percula
ENSG00000135930	EIF4E2	97	89.427	ENSATEG00000014136	eif4e2rs1	87	89.083	Anabas_testudineus
ENSG00000135930	EIF4E2	99	96.682	ENSAPLG00000016200	-	99	95.413	Anas_platyrhynchos
ENSG00000135930	EIF4E2	100	96.610	ENSACAG00000010833	EIF4E2	91	96.610	Anolis_carolinensis
ENSG00000135930	EIF4E2	100	99.592	ENSANAG00000021475	EIF4E2	100	99.592	Aotus_nancymaae
ENSG00000135930	EIF4E2	97	88.106	ENSACLG00000001038	eif4e2rs1	85	88.210	Astatotilapia_calliptera
ENSG00000135930	EIF4E2	99	87.288	ENSAMXG00000007905	eif4e2rs1	99	89.407	Astyanax_mexicanus
ENSG00000135930	EIF4E2	100	99.576	ENSBTAG00000010598	EIF4E2	100	99.576	Bos_taurus
ENSG00000135930	EIF4E2	99	99.057	ENSBTAG00000054466	-	99	99.556	Bos_taurus
ENSG00000135930	EIF4E2	99	92.149	ENSCJAG00000012387	-	98	92.105	Callithrix_jacchus
ENSG00000135930	EIF4E2	100	99.184	ENSCJAG00000013786	-	100	99.184	Callithrix_jacchus
ENSG00000135930	EIF4E2	99	99.052	ENSCAFG00000011328	EIF4E2	99	96.903	Canis_familiaris
ENSG00000135930	EIF4E2	99	83.491	ENSCAFG00000017487	-	95	83.406	Canis_familiaris
ENSG00000135930	EIF4E2	99	97.170	ENSCAFG00000012558	-	100	95.918	Canis_familiaris
ENSG00000135930	EIF4E2	93	92.000	ENSCAFG00000008828	-	100	91.304	Canis_familiaris
ENSG00000135930	EIF4E2	100	81.500	ENSCAFG00020008228	-	100	81.500	Canis_lupus_dingo
ENSG00000135930	EIF4E2	99	97.170	ENSCAFG00020001912	-	95	94.017	Canis_lupus_dingo
ENSG00000135930	EIF4E2	99	91.038	ENSCAFG00020003901	-	94	92.105	Canis_lupus_dingo
ENSG00000135930	EIF4E2	99	99.052	ENSCAFG00020023208	-	99	99.160	Canis_lupus_dingo
ENSG00000135930	EIF4E2	97	83.696	ENSCAFG00020018031	-	91	83.696	Canis_lupus_dingo
ENSG00000135930	EIF4E2	100	99.184	ENSCHIG00000021560	EIF4E2	100	99.184	Capra_hircus
ENSG00000135930	EIF4E2	100	99.592	ENSTSYG00000013980	EIF4E2	100	99.592	Carlito_syrichta
ENSG00000135930	EIF4E2	84	90.338	ENSCAPG00000009419	EIF4E2	99	90.338	Cavia_aperea
ENSG00000135930	EIF4E2	100	99.184	ENSCPOG00000005668	EIF4E2	100	99.184	Cavia_porcellus
ENSG00000135930	EIF4E2	100	99.592	ENSCCAG00000019970	EIF4E2	100	99.592	Cebus_capucinus
ENSG00000135930	EIF4E2	100	100.000	ENSCATG00000035393	EIF4E2	100	100.000	Cercocebus_atys
ENSG00000135930	EIF4E2	100	98.776	ENSCLAG00000008745	EIF4E2	100	98.776	Chinchilla_lanigera
ENSG00000135930	EIF4E2	100	100.000	ENSCSAG00000006468	EIF4E2	100	100.000	Chlorocebus_sabaeus
ENSG00000135930	EIF4E2	61	98.400	ENSCHOG00000013109	EIF4E2	61	98.400	Choloepus_hoffmanni
ENSG00000135930	EIF4E2	100	98.291	ENSCPBG00000016187	EIF4E2	100	98.291	Chrysemys_picta_bellii
ENSG00000135930	EIF4E2	99	65.517	ENSCING00000002342	-	99	65.517	Ciona_intestinalis
ENSG00000135930	EIF4E2	99	64.455	ENSCSAVG00000007532	-	99	63.717	Ciona_savignyi
ENSG00000135930	EIF4E2	100	100.000	ENSCANG00000040030	EIF4E2	100	100.000	Colobus_angolensis_palliatus
ENSG00000135930	EIF4E2	100	98.776	ENSCGRG00001003718	Eif4e2	100	98.776	Cricetulus_griseus_chok1gshd
ENSG00000135930	EIF4E2	100	98.122	ENSCGRG00000014565	Eif4e2	100	98.690	Cricetulus_griseus_crigri
ENSG00000135930	EIF4E2	97	88.546	ENSCSEG00000014782	eif4e2rs1	99	86.957	Cynoglossus_semilaevis
ENSG00000135930	EIF4E2	99	86.854	ENSCVAG00000005720	eif4e2rs1	97	87.225	Cyprinodon_variegatus
ENSG00000135930	EIF4E2	99	88.983	ENSDARG00000038585	eif4e2	99	97.037	Danio_rerio
ENSG00000135930	EIF4E2	100	99.153	ENSDNOG00000016877	EIF4E2	100	99.153	Dasypus_novemcinctus
ENSG00000135930	EIF4E2	100	84.322	ENSDORG00000011357	Eif4e2	100	85.897	Dipodomys_ordii
ENSG00000135930	EIF4E2	81	98.266	ENSETEG00000007930	EIF4E2	94	81.013	Echinops_telfairi
ENSG00000135930	EIF4E2	99	77.725	ENSEBUG00000012635	eif4e2rs1	97	78.761	Eptatretus_burgeri
ENSG00000135930	EIF4E2	99	98.578	ENSEASG00005019634	EIF4E2	99	98.739	Equus_asinus_asinus
ENSG00000135930	EIF4E2	100	98.776	ENSECAG00000020187	EIF4E2	100	98.776	Equus_caballus
ENSG00000135930	EIF4E2	81	84.211	ENSECAG00000031677	-	89	84.177	Equus_caballus
ENSG00000135930	EIF4E2	99	99.057	ENSEEUG00000015153	EIF4E2	93	97.890	Erinaceus_europaeus
ENSG00000135930	EIF4E2	99	86.864	ENSELUG00000010780	eif4e2rs1	99	86.864	Esox_lucius
ENSG00000135930	EIF4E2	100	99.184	ENSFCAG00000005684	EIF4E2	100	99.184	Felis_catus
ENSG00000135930	EIF4E2	66	83.065	ENSFCAG00000024388	-	89	82.677	Felis_catus
ENSG00000135930	EIF4E2	99	95.755	ENSFALG00000007749	EIF4E2	93	88.048	Ficedula_albicollis
ENSG00000135930	EIF4E2	100	99.592	ENSFDAG00000002829	EIF4E2	100	99.592	Fukomys_damarensis
ENSG00000135930	EIF4E2	99	88.732	ENSFHEG00000003036	eif4e2rs1	97	89.427	Fundulus_heteroclitus
ENSG00000135930	EIF4E2	95	88.288	ENSGMOG00000012027	eif4e2rs1	95	88.288	Gadus_morhua
ENSG00000135930	EIF4E2	100	96.610	ENSGALG00000007919	EIF4E2	100	96.610	Gallus_gallus
ENSG00000135930	EIF4E2	100	87.850	ENSGAFG00000009143	eif4e2rs1	75	87.444	Gambusia_affinis
ENSG00000135930	EIF4E2	99	88.511	ENSGACG00000015090	eif4e2rs1	99	88.511	Gasterosteus_aculeatus
ENSG00000135930	EIF4E2	100	98.305	ENSGAGG00000004145	EIF4E2	100	98.305	Gopherus_agassizii
ENSG00000135930	EIF4E2	100	77.551	ENSGGOG00000036742	-	100	77.551	Gorilla_gorilla
ENSG00000135930	EIF4E2	100	100.000	ENSGGOG00000043810	-	100	100.000	Gorilla_gorilla
ENSG00000135930	EIF4E2	100	77.551	ENSGGOG00000041594	-	100	77.551	Gorilla_gorilla
ENSG00000135930	EIF4E2	99	88.136	ENSHBUG00000022968	eif4e2rs1	86	88.559	Haplochromis_burtoni
ENSG00000135930	EIF4E2	100	99.184	ENSHGLG00000002618	EIF4E2	100	99.184	Heterocephalus_glaber_female
ENSG00000135930	EIF4E2	100	72.487	ENSHGLG00000017721	-	92	84.459	Heterocephalus_glaber_female
ENSG00000135930	EIF4E2	100	91.026	ENSHGLG00000020005	-	100	91.026	Heterocephalus_glaber_female
ENSG00000135930	EIF4E2	100	99.184	ENSHGLG00100011358	EIF4E2	100	99.184	Heterocephalus_glaber_male
ENSG00000135930	EIF4E2	100	91.026	ENSHGLG00100021090	-	100	91.026	Heterocephalus_glaber_male
ENSG00000135930	EIF4E2	100	72.487	ENSHGLG00100008686	-	92	84.459	Heterocephalus_glaber_male
ENSG00000135930	EIF4E2	72	97.794	ENSHCOG00000019049	-	84	97.794	Hippocampus_comes
ENSG00000135930	EIF4E2	99	86.854	ENSHCOG00000000972	eif4e2rs1	93	88.000	Hippocampus_comes
ENSG00000135930	EIF4E2	99	87.712	ENSIPUG00000018927	eif4e2	99	89.407	Ictalurus_punctatus
ENSG00000135930	EIF4E2	100	99.592	ENSSTOG00000003508	EIF4E2	100	99.592	Ictidomys_tridecemlineatus
ENSG00000135930	EIF4E2	99	98.104	ENSJJAG00000022718	Eif4e2	100	98.253	Jaculus_jaculus
ENSG00000135930	EIF4E2	99	87.736	ENSKMAG00000005213	eif4e2rs1	97	90.308	Kryptolebias_marmoratus
ENSG00000135930	EIF4E2	97	90.749	ENSLBEG00000023869	eif4e2rs1	97	90.749	Labrus_bergylta
ENSG00000135930	EIF4E2	99	95.283	ENSLACG00000015940	EIF4E2	99	95.279	Latimeria_chalumnae
ENSG00000135930	EIF4E2	81	97.674	ENSLOCG00000005798	eif4e2rs1	99	97.354	Lepisosteus_oculatus
ENSG00000135930	EIF4E2	99	99.528	ENSLAFG00000011554	EIF4E2	100	99.548	Loxodonta_africana
ENSG00000135930	EIF4E2	100	100.000	ENSMFAG00000002558	EIF4E2	100	100.000	Macaca_fascicularis
ENSG00000135930	EIF4E2	100	100.000	ENSMMUG00000022151	EIF4E2	100	100.000	Macaca_mulatta
ENSG00000135930	EIF4E2	100	100.000	ENSMNEG00000038383	EIF4E2	100	100.000	Macaca_nemestrina
ENSG00000135930	EIF4E2	100	100.000	ENSMLEG00000036508	EIF4E2	100	100.000	Mandrillus_leucophaeus
ENSG00000135930	EIF4E2	99	90.254	ENSMAMG00000010881	eif4e2rs1	99	90.254	Mastacembelus_armatus
ENSG00000135930	EIF4E2	85	93.333	ENSMZEG00005019218	eif4e2rs1	90	88.584	Maylandia_zebra
ENSG00000135930	EIF4E2	99	95.755	ENSMGAG00000008475	EIF4E2	97	93.534	Meleagris_gallopavo
ENSG00000135930	EIF4E2	100	98.729	ENSMAUG00000002151	Eif4e2	100	98.729	Mesocricetus_auratus
ENSG00000135930	EIF4E2	99	85.537	ENSMICG00000031527	-	100	84.000	Microcebus_murinus
ENSG00000135930	EIF4E2	100	85.306	ENSMICG00000015082	-	100	99.174	Microcebus_murinus
ENSG00000135930	EIF4E2	100	99.153	ENSMOCG00000008758	Eif4e2	100	99.153	Microtus_ochrogaster
ENSG00000135930	EIF4E2	96	90.667	ENSMMOG00000011657	eif4e2rs1	88	90.667	Mola_mola
ENSG00000135930	EIF4E2	100	96.327	ENSMODG00000002680	EIF4E2	100	96.327	Monodelphis_domestica
ENSG00000135930	EIF4E2	97	89.427	ENSMALG00000019167	eif4e2rs1	97	89.868	Monopterus_albus
ENSG00000135930	EIF4E2	100	97.959	MGP_CAROLIEiJ_G0014377	Eif4e2	100	97.959	Mus_caroli
ENSG00000135930	EIF4E2	100	98.367	ENSMUSG00000026254	Eif4e2	100	98.367	Mus_musculus
ENSG00000135930	EIF4E2	100	98.367	MGP_PahariEiJ_G0027614	Eif4e2	100	98.367	Mus_pahari
ENSG00000135930	EIF4E2	100	98.367	MGP_SPRETEiJ_G0015179	Eif4e2	100	98.367	Mus_spretus
ENSG00000135930	EIF4E2	99	99.052	ENSMPUG00000005206	-	99	98.347	Mustela_putorius_furo
ENSG00000135930	EIF4E2	93	96.985	ENSMPUG00000019961	-	100	92.593	Mustela_putorius_furo
ENSG00000135930	EIF4E2	100	99.184	ENSMLUG00000022413	-	100	99.184	Myotis_lucifugus
ENSG00000135930	EIF4E2	100	99.184	ENSMLUG00000011269	-	100	99.184	Myotis_lucifugus
ENSG00000135930	EIF4E2	100	99.576	ENSNGAG00000023460	Eif4e2	100	99.576	Nannospalax_galili
ENSG00000135930	EIF4E2	99	87.764	ENSNBRG00000018517	eif4e2rs1	99	88.186	Neolamprologus_brichardi
ENSG00000135930	EIF4E2	100	99.592	ENSNLEG00000014333	EIF4E2	100	99.592	Nomascus_leucogenys
ENSG00000135930	EIF4E2	100	97.959	ENSMEUG00000015519	EIF4E2	100	97.959	Notamacropus_eugenii
ENSG00000135930	EIF4E2	99	75.472	ENSOPRG00000013054	EIF4E2	94	76.793	Ochotona_princeps
ENSG00000135930	EIF4E2	100	84.186	ENSODEG00000015909	-	100	83.721	Octodon_degus
ENSG00000135930	EIF4E2	100	96.327	ENSODEG00000020085	-	81	96.327	Octodon_degus
ENSG00000135930	EIF4E2	100	99.153	ENSODEG00000008170	-	100	99.153	Octodon_degus
ENSG00000135930	EIF4E2	100	73.000	ENSODEG00000001996	-	80	73.000	Octodon_degus
ENSG00000135930	EIF4E2	100	73.469	ENSODEG00000010986	-	100	73.469	Octodon_degus
ENSG00000135930	EIF4E2	99	88.983	ENSONIG00000010085	eif4e2rs1	99	89.407	Oreochromis_niloticus
ENSG00000135930	EIF4E2	99	97.630	ENSOCUG00000004535	EIF4E2	100	94.694	Oryctolagus_cuniculus
ENSG00000135930	EIF4E2	97	88.106	ENSORLG00000015731	eif4e2	97	88.106	Oryzias_latipes
ENSG00000135930	EIF4E2	97	87.225	ENSORLG00020015829	eif4e2rs1	97	88.987	Oryzias_latipes_hni
ENSG00000135930	EIF4E2	97	88.546	ENSORLG00015015904	eif4e2rs1	97	88.546	Oryzias_latipes_hsok
ENSG00000135930	EIF4E2	99	88.983	ENSOMEG00000022558	eif4e2rs1	99	88.983	Oryzias_melastigma
ENSG00000135930	EIF4E2	98	84.937	ENSOGAG00000009155	-	100	84.937	Otolemur_garnettii
ENSG00000135930	EIF4E2	99	96.721	ENSOGAG00000031078	-	99	96.721	Otolemur_garnettii
ENSG00000135930	EIF4E2	99	99.526	ENSOARG00000020823	-	99	96.721	Ovis_aries
ENSG00000135930	EIF4E2	73	99.270	ENSOARG00000020824	-	96	99.270	Ovis_aries
ENSG00000135930	EIF4E2	100	69.388	ENSPPAG00000030709	-	100	69.388	Pan_paniscus
ENSG00000135930	EIF4E2	100	100.000	ENSPPAG00000034717	EIF4E2	100	100.000	Pan_paniscus
ENSG00000135930	EIF4E2	99	81.313	ENSPPRG00000003939	-	99	81.313	Panthera_pardus
ENSG00000135930	EIF4E2	100	99.184	ENSPPRG00000002758	-	100	99.184	Panthera_pardus
ENSG00000135930	EIF4E2	99	99.052	ENSPTIG00000007811	EIF4E2	97	99.160	Panthera_tigris_altaica
ENSG00000135930	EIF4E2	100	69.388	ENSPTRG00000047830	-	100	69.388	Pan_troglodytes
ENSG00000135930	EIF4E2	100	100.000	ENSPTRG00000013043	EIF4E2	100	100.000	Pan_troglodytes
ENSG00000135930	EIF4E2	100	100.000	ENSPANG00000015728	EIF4E2	100	100.000	Papio_anubis
ENSG00000135930	EIF4E2	99	88.136	ENSPKIG00000014411	eif4e2rs1	99	88.983	Paramormyrops_kingsleyae
ENSG00000135930	EIF4E2	100	97.653	ENSPSIG00000012188	EIF4E2	98	96.170	Pelodiscus_sinensis
ENSG00000135930	EIF4E2	85	94.444	ENSPMGG00000014684	eif4e2rs1	100	88.559	Periophthalmus_magnuspinnatus
ENSG00000135930	EIF4E2	100	98.729	ENSPEMG00000001974	Eif4e2	100	98.729	Peromyscus_maniculatus_bairdii
ENSG00000135930	EIF4E2	99	84.360	ENSPMAG00000005916	eif4e2rs1	99	83.843	Petromyzon_marinus
ENSG00000135930	EIF4E2	100	98.729	ENSPCIG00000002486	-	100	98.729	Phascolarctos_cinereus
ENSG00000135930	EIF4E2	99	88.679	ENSPFOG00000005221	eif4e2rs1	99	85.714	Poecilia_formosa
ENSG00000135930	EIF4E2	99	89.362	ENSPLAG00000002275	eif4e2rs1	99	89.362	Poecilia_latipinna
ENSG00000135930	EIF4E2	99	89.362	ENSPMEG00000004371	eif4e2rs1	99	89.362	Poecilia_mexicana
ENSG00000135930	EIF4E2	91	91.237	ENSPREG00000016132	eif4e2rs1	93	88.889	Poecilia_reticulata
ENSG00000135930	EIF4E2	100	100.000	ENSPPYG00000013282	-	100	100.000	Pongo_abelii
ENSG00000135930	EIF4E2	100	83.740	ENSPCAG00000016171	EIF4E2	100	83.740	Procavia_capensis
ENSG00000135930	EIF4E2	99	81.604	ENSPCOG00000003822	-	99	82.110	Propithecus_coquereli
ENSG00000135930	EIF4E2	100	99.153	ENSPCOG00000017497	EIF4E2	100	99.153	Propithecus_coquereli
ENSG00000135930	EIF4E2	100	98.367	ENSPVAG00000007494	EIF4E2	100	98.367	Pteropus_vampyrus
ENSG00000135930	EIF4E2	99	88.559	ENSPNYG00000008188	eif4e2rs1	86	88.983	Pundamilia_nyererei
ENSG00000135930	EIF4E2	99	87.712	ENSPNAG00000007063	eif4e2rs1	99	89.831	Pygocentrus_nattereri
ENSG00000135930	EIF4E2	100	97.653	ENSRNOG00000019634	Eif4e2	99	97.817	Rattus_norvegicus
ENSG00000135930	EIF4E2	100	99.592	ENSRBIG00000044887	EIF4E2	100	99.592	Rhinopithecus_bieti
ENSG00000135930	EIF4E2	99	66.162	ENSRBIG00000038478	-	98	66.162	Rhinopithecus_bieti
ENSG00000135930	EIF4E2	95	67.368	ENSRROG00000035835	-	96	67.368	Rhinopithecus_roxellana
ENSG00000135930	EIF4E2	100	100.000	ENSRROG00000043570	EIF4E2	100	100.000	Rhinopithecus_roxellana
ENSG00000135930	EIF4E2	100	99.576	ENSSBOG00000007474	EIF4E2	100	99.576	Saimiri_boliviensis_boliviensis
ENSG00000135930	EIF4E2	65	88.489	ENSSHAG00000017500	-	99	89.510	Sarcophilus_harrisii
ENSG00000135930	EIF4E2	99	99.057	ENSSHAG00000013108	-	98	97.510	Sarcophilus_harrisii
ENSG00000135930	EIF4E2	99	90.678	ENSSFOG00015010899	eif4e2rs1	99	97.037	Scleropages_formosus
ENSG00000135930	EIF4E2	97	88.987	ENSSMAG00000001480	eif4e2rs1	97	88.987	Scophthalmus_maximus
ENSG00000135930	EIF4E2	97	89.868	ENSSDUG00000017033	eif4e2rs1	97	89.868	Seriola_dumerili
ENSG00000135930	EIF4E2	91	92.268	ENSSLDG00000023267	eif4e2rs1	97	89.130	Seriola_lalandi_dorsalis
ENSG00000135930	EIF4E2	99	81.517	ENSSARG00000001058	EIF4E2	93	81.304	Sorex_araneus
ENSG00000135930	EIF4E2	100	98.291	ENSSPUG00000012423	EIF4E2	100	98.291	Sphenodon_punctatus
ENSG00000135930	EIF4E2	97	89.868	ENSSPAG00000023256	eif4e2rs1	97	89.868	Stegastes_partitus
ENSG00000135930	EIF4E2	100	98.942	ENSSSCG00000038466	EIF4E2	100	98.942	Sus_scrofa
ENSG00000135930	EIF4E2	99	96.209	ENSTGUG00000009955	EIF4E2	100	95.652	Taeniopygia_guttata
ENSG00000135930	EIF4E2	99	89.407	ENSTRUG00000014558	eif4e2rs1	99	89.831	Takifugu_rubripes
ENSG00000135930	EIF4E2	99	98.113	ENSTBEG00000004455	EIF4E2	93	97.046	Tupaia_belangeri
ENSG00000135930	EIF4E2	100	98.776	ENSTTRG00000010927	EIF4E2	100	98.776	Tursiops_truncatus
ENSG00000135930	EIF4E2	100	99.184	ENSUAMG00000020509	-	100	99.184	Ursus_americanus
ENSG00000135930	EIF4E2	100	74.000	ENSUAMG00000006004	-	100	74.000	Ursus_americanus
ENSG00000135930	EIF4E2	100	74.000	ENSUMAG00000021850	-	100	74.000	Ursus_maritimus
ENSG00000135930	EIF4E2	99	99.052	ENSUMAG00000015622	-	94	99.160	Ursus_maritimus
ENSG00000135930	EIF4E2	99	89.100	ENSVPAG00000010680	EIF4E2	100	90.336	Vicugna_pacos
ENSG00000135930	EIF4E2	100	89.000	ENSVVUG00000011153	-	100	89.000	Vulpes_vulpes
ENSG00000135930	EIF4E2	99	78.774	ENSVVUG00000008165	-	89	79.821	Vulpes_vulpes
ENSG00000135930	EIF4E2	100	98.776	ENSVVUG00000013736	-	100	98.776	Vulpes_vulpes
ENSG00000135930	EIF4E2	100	96.500	ENSVVUG00000004051	-	100	96.500	Vulpes_vulpes
ENSG00000135930	EIF4E2	99	98.578	ENSVVUG00000025506	-	99	98.319	Vulpes_vulpes
ENSG00000135930	EIF4E2	100	94.444	ENSXETG00000027885	mgc89871	96	94.444	Xenopus_tropicalis
ENSG00000135930	EIF4E2	95	89.444	ENSXCOG00000008291	eif4e2rs1	98	89.524	Xiphophorus_couchianus
ENSG00000135930	EIF4E2	99	88.983	ENSXMAG00000008587	eif4e2rs1	99	88.983	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000339	RNA cap binding	9582349.	TAS	Function
GO:0000340	RNA 7-methylguanosine cap binding	21873635.	IBA	Function
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0005515	protein binding	16189514.17368478.19060904.22678294.25416956.	IPI	Function
GO:0005829	cytosol	-	TAS	Component
GO:0005845	mRNA cap binding complex	17368478.	IDA	Component
GO:0006413	translational initiation	-	IEA	Process
GO:0008135	translation factor activity, RNA binding	9582349.	TAS	Function
GO:0016281	eukaryotic translation initiation factor 4F complex	21873635.	IBA	Component
GO:0017148	negative regulation of translation	22751931.	IMP	Process
GO:0031625	ubiquitin protein ligase binding	14623119.	IPI	Function