EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000135972 (Gene tree)
Gene ID: 64965
Gene Symbol: MRPS9
Alias: RPMS9|MRP-S9|S9mt
Full Name: mitochondrial ribosomal protein S9
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 61,978 bases
Position: chr2:105,037,983-105,099,960
Accession: 14501
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000258455	Ribosomal_S9	PF00380.19	1.4e-37	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000413583	MRPS9-202	652	-	ENSP00000388885	57 (aa)	-	H7BZC4
ENST00000472220	MRPS9-203	982	-	-	- (aa)	-	-
ENST00000258455	MRPS9-201	1500	XM_011511644	ENSP00000258455	396 (aa)	XP_011509946	P82933

Gene Model

Click here to download ENSG00000135972's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000135972	Pancreatic Neoplasms	7.134E-05	22523087
ENSG00000135972	Basophils	8.3430000E-005	-
ENSG00000135972	Platelet Function Tests	4.8688903E-006	-
ENSG00000135972	Diabetes Mellitus, Type 2	6E-6	17668382

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135972's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000135972	MRPS9	100	56.818	ENSAPOG00000005208	mrps9	100	56.818	Acanthochromis_polyacanthus
ENSG00000135972	MRPS9	100	82.323	ENSAMEG00000013254	MRPS9	100	82.323	Ailuropoda_melanoleuca
ENSG00000135972	MRPS9	100	56.061	ENSACIG00000024089	mrps9	100	56.061	Amphilophus_citrinellus
ENSG00000135972	MRPS9	95	59.200	ENSAOCG00000017749	mrps9	98	59.200	Amphiprion_ocellaris
ENSG00000135972	MRPS9	95	59.200	ENSAPEG00000013413	mrps9	98	59.200	Amphiprion_percula
ENSG00000135972	MRPS9	87	56.196	ENSATEG00000015199	mrps9	97	56.196	Anabas_testudineus
ENSG00000135972	MRPS9	76	70.627	ENSAPLG00000013899	MRPS9	100	70.627	Anas_platyrhynchos
ENSG00000135972	MRPS9	85	65.875	ENSACAG00000011232	MRPS9	92	65.875	Anolis_carolinensis
ENSG00000135972	MRPS9	100	85.859	ENSANAG00000028319	-	100	85.859	Aotus_nancymaae
ENSG00000135972	MRPS9	99	83.586	ENSANAG00000032983	-	99	83.586	Aotus_nancymaae
ENSG00000135972	MRPS9	100	89.646	ENSANAG00000021821	-	100	89.646	Aotus_nancymaae
ENSG00000135972	MRPS9	100	56.784	ENSACLG00000010815	mrps9	100	56.784	Astatotilapia_calliptera
ENSG00000135972	MRPS9	85	63.609	ENSAMXG00000009629	mrps9	88	63.609	Astyanax_mexicanus
ENSG00000135972	MRPS9	100	78.535	ENSBTAG00000006150	MRPS9	100	78.535	Bos_taurus
ENSG00000135972	MRPS9	82	33.524	WBGene00017319	mrps-9	88	33.524	Caenorhabditis_elegans
ENSG00000135972	MRPS9	100	89.141	ENSCJAG00000008156	-	100	89.141	Callithrix_jacchus
ENSG00000135972	MRPS9	100	89.141	ENSCJAG00000022933	-	100	89.141	Callithrix_jacchus
ENSG00000135972	MRPS9	100	82.828	ENSCAFG00000002122	MRPS9	100	82.828	Canis_familiaris
ENSG00000135972	MRPS9	100	82.828	ENSCAFG00020010507	MRPS9	100	82.828	Canis_lupus_dingo
ENSG00000135972	MRPS9	100	79.545	ENSCHIG00000022475	MRPS9	100	79.545	Capra_hircus
ENSG00000135972	MRPS9	89	72.549	ENSTSYG00000010423	MRPS9	100	87.692	Carlito_syrichta
ENSG00000135972	MRPS9	100	74.747	ENSCPOG00000013967	MRPS9	100	74.747	Cavia_porcellus
ENSG00000135972	MRPS9	100	86.869	ENSCCAG00000028813	-	100	86.869	Cebus_capucinus
ENSG00000135972	MRPS9	100	79.798	ENSCCAG00000028196	-	100	79.798	Cebus_capucinus
ENSG00000135972	MRPS9	98	81.748	ENSCCAG00000024066	-	100	81.748	Cebus_capucinus
ENSG00000135972	MRPS9	100	91.162	ENSCATG00000036678	MRPS9	100	91.162	Cercocebus_atys
ENSG00000135972	MRPS9	100	75.758	ENSCLAG00000005209	MRPS9	91	75.758	Chinchilla_lanigera
ENSG00000135972	MRPS9	100	90.909	ENSCSAG00000017079	MRPS9	100	90.909	Chlorocebus_sabaeus
ENSG00000135972	MRPS9	89	83.761	ENSCHOG00000003198	MRPS9	100	83.761	Choloepus_hoffmanni
ENSG00000135972	MRPS9	89	71.388	ENSCPBG00000007214	MRPS9	99	68.533	Chrysemys_picta_bellii
ENSG00000135972	MRPS9	100	91.919	ENSCANG00000035795	MRPS9	100	91.919	Colobus_angolensis_palliatus
ENSG00000135972	MRPS9	100	77.273	ENSCGRG00001012228	Mrps9	100	77.273	Cricetulus_griseus_chok1gshd
ENSG00000135972	MRPS9	100	77.273	ENSCGRG00000007505	Mrps9	100	77.273	Cricetulus_griseus_crigri
ENSG00000135972	MRPS9	86	58.772	ENSCSEG00000003508	mrps9	82	58.772	Cynoglossus_semilaevis
ENSG00000135972	MRPS9	89	61.648	ENSCVAG00000007791	mrps9	93	61.648	Cyprinodon_variegatus
ENSG00000135972	MRPS9	99	56.203	ENSDARG00000061505	mrps9	100	56.203	Danio_rerio
ENSG00000135972	MRPS9	100	77.694	ENSDNOG00000006994	MRPS9	100	77.694	Dasypus_novemcinctus
ENSG00000135972	MRPS9	100	81.818	ENSDORG00000012465	Mrps9	100	81.818	Dipodomys_ordii
ENSG00000135972	MRPS9	84	46.547	FBgn0037529	mRpS9	84	46.547	Drosophila_melanogaster
ENSG00000135972	MRPS9	100	68.090	ENSETEG00000014167	MRPS9	100	68.090	Echinops_telfairi
ENSG00000135972	MRPS9	74	54.949	ENSEBUG00000009642	mrps9	91	54.949	Eptatretus_burgeri
ENSG00000135972	MRPS9	100	80.303	ENSEASG00005017804	MRPS9	100	80.303	Equus_asinus_asinus
ENSG00000135972	MRPS9	100	81.313	ENSECAG00000011157	MRPS9	100	81.313	Equus_caballus
ENSG00000135972	MRPS9	100	60.354	ENSEEUG00000000989	MRPS9	100	60.354	Erinaceus_europaeus
ENSG00000135972	MRPS9	95	59.043	ENSELUG00000006431	mrps9	98	59.043	Esox_lucius
ENSG00000135972	MRPS9	100	83.081	ENSFCAG00000031722	MRPS9	100	83.081	Felis_catus
ENSG00000135972	MRPS9	88	68.857	ENSFALG00000003647	MRPS9	100	68.857	Ficedula_albicollis
ENSG00000135972	MRPS9	100	76.515	ENSFDAG00000004645	MRPS9	100	76.515	Fukomys_damarensis
ENSG00000135972	MRPS9	86	63.422	ENSFHEG00000008856	mrps9	96	63.422	Fundulus_heteroclitus
ENSG00000135972	MRPS9	95	67.109	ENSGALG00000016794	MRPS9	98	58.621	Gallus_gallus
ENSG00000135972	MRPS9	86	63.127	ENSGAFG00000009850	mrps9	89	63.127	Gambusia_affinis
ENSG00000135972	MRPS9	88	72.286	ENSGAGG00000003622	MRPS9	99	72.286	Gopherus_agassizii
ENSG00000135972	MRPS9	100	99.242	ENSGGOG00000007751	MRPS9	100	99.242	Gorilla_gorilla
ENSG00000135972	MRPS9	100	56.784	ENSHBUG00000005067	mrps9	100	56.784	Haplochromis_burtoni
ENSG00000135972	MRPS9	100	77.020	ENSHGLG00000011532	MRPS9	100	77.020	Heterocephalus_glaber_female
ENSG00000135972	MRPS9	100	77.273	ENSHGLG00100014404	MRPS9	100	77.273	Heterocephalus_glaber_male
ENSG00000135972	MRPS9	100	55.919	ENSHCOG00000003338	mrps9	100	55.919	Hippocampus_comes
ENSG00000135972	MRPS9	86	63.422	ENSIPUG00000012385	MRPS9	88	63.422	Ictalurus_punctatus
ENSG00000135972	MRPS9	100	85.101	ENSSTOG00000016370	MRPS9	100	85.101	Ictidomys_tridecemlineatus
ENSG00000135972	MRPS9	100	73.232	ENSJJAG00000001151	-	100	73.232	Jaculus_jaculus
ENSG00000135972	MRPS9	100	76.768	ENSJJAG00000010770	-	100	76.768	Jaculus_jaculus
ENSG00000135972	MRPS9	86	61.062	ENSKMAG00000003005	mrps9	89	61.062	Kryptolebias_marmoratus
ENSG00000135972	MRPS9	100	56.566	ENSLBEG00000006954	mrps9	87	56.566	Labrus_bergylta
ENSG00000135972	MRPS9	89	50.980	ENSLACG00000013746	MRPS9	100	61.373	Latimeria_chalumnae
ENSG00000135972	MRPS9	90	67.039	ENSLOCG00000008722	mrps9	92	67.039	Lepisosteus_oculatus
ENSG00000135972	MRPS9	100	77.273	ENSLAFG00000008097	MRPS9	100	77.273	Loxodonta_africana
ENSG00000135972	MRPS9	100	90.404	ENSMFAG00000039793	MRPS9	100	90.404	Macaca_fascicularis
ENSG00000135972	MRPS9	100	90.404	ENSMMUG00000019682	MRPS9	100	90.404	Macaca_mulatta
ENSG00000135972	MRPS9	100	90.404	ENSMNEG00000034038	MRPS9	100	90.404	Macaca_nemestrina
ENSG00000135972	MRPS9	100	90.909	ENSMLEG00000042789	MRPS9	100	90.909	Mandrillus_leucophaeus
ENSG00000135972	MRPS9	100	58.603	ENSMAMG00000022287	mrps9	100	58.603	Mastacembelus_armatus
ENSG00000135972	MRPS9	100	56.533	ENSMZEG00005015264	mrps9	100	56.533	Maylandia_zebra
ENSG00000135972	MRPS9	88	69.429	ENSMGAG00000014818	MRPS9	100	69.429	Meleagris_gallopavo
ENSG00000135972	MRPS9	100	77.778	ENSMAUG00000014517	Mrps9	100	77.778	Mesocricetus_auratus
ENSG00000135972	MRPS9	100	87.657	ENSMICG00000000223	MRPS9	100	87.657	Microcebus_murinus
ENSG00000135972	MRPS9	100	77.273	ENSMOCG00000008753	Mrps9	100	77.273	Microtus_ochrogaster
ENSG00000135972	MRPS9	83	59.819	ENSMMOG00000021068	mrps9	96	58.529	Mola_mola
ENSG00000135972	MRPS9	100	74.811	ENSMODG00000002479	MRPS9	100	74.811	Monodelphis_domestica
ENSG00000135972	MRPS9	87	61.449	ENSMALG00000019855	mrps9	93	58.924	Monopterus_albus
ENSG00000135972	MRPS9	100	77.273	MGP_CAROLIEiJ_G0014088	Mrps9	98	77.273	Mus_caroli
ENSG00000135972	MRPS9	100	77.273	ENSMUSG00000060679	Mrps9	100	77.273	Mus_musculus
ENSG00000135972	MRPS9	100	77.020	MGP_PahariEiJ_G0027333	Mrps9	100	77.020	Mus_pahari
ENSG00000135972	MRPS9	100	77.778	MGP_SPRETEiJ_G0014892	Mrps9	100	77.778	Mus_spretus
ENSG00000135972	MRPS9	93	82.016	ENSMPUG00000010853	MRPS9	92	82.016	Mustela_putorius_furo
ENSG00000135972	MRPS9	100	80.808	ENSMLUG00000001715	MRPS9	100	80.808	Myotis_lucifugus
ENSG00000135972	MRPS9	100	78.788	ENSNGAG00000020814	Mrps9	100	78.788	Nannospalax_galili
ENSG00000135972	MRPS9	100	49.246	ENSNBRG00000016845	mrps9	100	49.246	Neolamprologus_brichardi
ENSG00000135972	MRPS9	100	96.212	ENSNLEG00000032880	MRPS9	100	96.212	Nomascus_leucogenys
ENSG00000135972	MRPS9	89	63.533	ENSMEUG00000013188	MRPS9	100	63.533	Notamacropus_eugenii
ENSG00000135972	MRPS9	100	68.939	ENSOPRG00000003758	-	100	68.939	Ochotona_princeps
ENSG00000135972	MRPS9	100	74.495	ENSODEG00000008818	MRPS9	100	74.495	Octodon_degus
ENSG00000135972	MRPS9	95	58.355	ENSONIG00000013457	mrps9	98	58.355	Oreochromis_niloticus
ENSG00000135972	MRPS9	76	76.412	ENSOANG00000012373	MRPS9	99	76.412	Ornithorhynchus_anatinus
ENSG00000135972	MRPS9	100	79.798	ENSOCUG00000015017	MRPS9	100	79.798	Oryctolagus_cuniculus
ENSG00000135972	MRPS9	86	62.281	ENSORLG00000001896	mrps9	80	62.281	Oryzias_latipes
ENSG00000135972	MRPS9	86	61.988	ENSORLG00020004081	mrps9	88	61.988	Oryzias_latipes_hni
ENSG00000135972	MRPS9	86	62.573	ENSORLG00015006913	mrps9	89	62.573	Oryzias_latipes_hsok
ENSG00000135972	MRPS9	86	63.158	ENSOMEG00000015064	mrps9	89	63.158	Oryzias_melastigma
ENSG00000135972	MRPS9	100	85.606	ENSOGAG00000007255	MRPS9	100	85.606	Otolemur_garnettii
ENSG00000135972	MRPS9	100	79.545	ENSOARG00000013000	MRPS9	100	79.545	Ovis_aries
ENSG00000135972	MRPS9	100	99.242	ENSPPAG00000037429	MRPS9	100	99.242	Pan_paniscus
ENSG00000135972	MRPS9	100	83.586	ENSPPRG00000009311	MRPS9	100	83.586	Panthera_pardus
ENSG00000135972	MRPS9	100	83.586	ENSPTIG00000019423	MRPS9	100	83.586	Panthera_tigris_altaica
ENSG00000135972	MRPS9	100	99.495	ENSPTRG00000012310	MRPS9	100	99.495	Pan_troglodytes
ENSG00000135972	MRPS9	100	78.535	ENSPANG00000012691	MRPS9	100	78.535	Papio_anubis
ENSG00000135972	MRPS9	87	63.873	ENSPKIG00000010542	mrps9	88	63.873	Paramormyrops_kingsleyae
ENSG00000135972	MRPS9	88	70.857	ENSPSIG00000015761	MRPS9	99	70.857	Pelodiscus_sinensis
ENSG00000135972	MRPS9	100	52.020	ENSPMGG00000015551	mrps9	99	56.800	Periophthalmus_magnuspinnatus
ENSG00000135972	MRPS9	100	73.552	ENSPEMG00000020068	Mrps9	100	73.552	Peromyscus_maniculatus_bairdii
ENSG00000135972	MRPS9	100	72.980	ENSPCIG00000016698	MRPS9	100	72.980	Phascolarctos_cinereus
ENSG00000135972	MRPS9	86	61.947	ENSPFOG00000013721	mrps9	89	61.947	Poecilia_formosa
ENSG00000135972	MRPS9	86	61.947	ENSPLAG00000008098	mrps9	92	59.706	Poecilia_latipinna
ENSG00000135972	MRPS9	86	61.947	ENSPMEG00000021477	mrps9	89	61.947	Poecilia_mexicana
ENSG00000135972	MRPS9	86	61.111	ENSPREG00000016254	mrps9	93	61.111	Poecilia_reticulata
ENSG00000135972	MRPS9	100	95.960	ENSPPYG00000012119	MRPS9	100	95.960	Pongo_abelii
ENSG00000135972	MRPS9	100	74.242	ENSPCAG00000008824	MRPS9	100	74.242	Procavia_capensis
ENSG00000135972	MRPS9	100	82.323	ENSPCOG00000018743	MRPS9	100	82.323	Propithecus_coquereli
ENSG00000135972	MRPS9	100	81.566	ENSPVAG00000000927	MRPS9	100	81.566	Pteropus_vampyrus
ENSG00000135972	MRPS9	100	57.286	ENSPNYG00000008697	mrps9	100	57.286	Pundamilia_nyererei
ENSG00000135972	MRPS9	86	65.487	ENSPNAG00000020186	mrps9	89	65.487	Pygocentrus_nattereri
ENSG00000135972	MRPS9	100	78.030	ENSRNOG00000016201	Mrps9	100	78.030	Rattus_norvegicus
ENSG00000135972	MRPS9	100	92.424	ENSRBIG00000025807	MRPS9	100	92.424	Rhinopithecus_bieti
ENSG00000135972	MRPS9	100	92.172	ENSRROG00000044430	MRPS9	100	92.172	Rhinopithecus_roxellana
ENSG00000135972	MRPS9	100	87.879	ENSSBOG00000035994	MRPS9	100	87.879	Saimiri_boliviensis_boliviensis
ENSG00000135972	MRPS9	100	74.242	ENSSHAG00000018119	MRPS9	100	79.016	Sarcophilus_harrisii
ENSG00000135972	MRPS9	92	60.822	ENSSFOG00015023159	mrps9	99	60.822	Scleropages_formosus
ENSG00000135972	MRPS9	86	62.832	ENSSMAG00000010712	mrps9	88	62.832	Scophthalmus_maximus
ENSG00000135972	MRPS9	95	57.979	ENSSDUG00000011236	mrps9	94	62.242	Seriola_dumerili
ENSG00000135972	MRPS9	95	57.447	ENSSLDG00000005169	mrps9	98	57.447	Seriola_lalandi_dorsalis
ENSG00000135972	MRPS9	100	69.192	ENSSARG00000011331	MRPS9	100	69.192	Sorex_araneus
ENSG00000135972	MRPS9	84	71.171	ENSSPUG00000005894	MRPS9	100	71.171	Sphenodon_punctatus
ENSG00000135972	MRPS9	86	60.882	ENSSPAG00000005960	mrps9	94	60.882	Stegastes_partitus
ENSG00000135972	MRPS9	100	81.612	ENSSSCG00000028020	MRPS9	100	81.612	Sus_scrofa
ENSG00000135972	MRPS9	88	70.286	ENSTGUG00000009773	MRPS9	100	70.286	Taeniopygia_guttata
ENSG00000135972	MRPS9	100	57.179	ENSTRUG00000010406	mrps9	100	57.179	Takifugu_rubripes
ENSG00000135972	MRPS9	83	61.515	ENSTNIG00000003463	mrps9	99	60.177	Tetraodon_nigroviridis
ENSG00000135972	MRPS9	89	78.063	ENSTBEG00000001933	MRPS9	100	78.063	Tupaia_belangeri
ENSG00000135972	MRPS9	100	74.495	ENSTTRG00000014572	MRPS9	100	74.495	Tursiops_truncatus
ENSG00000135972	MRPS9	100	81.566	ENSUAMG00000012215	MRPS9	98	83.626	Ursus_americanus
ENSG00000135972	MRPS9	100	81.566	ENSUMAG00000020795	MRPS9	100	81.566	Ursus_maritimus
ENSG00000135972	MRPS9	100	82.576	ENSVVUG00000012519	MRPS9	100	82.576	Vulpes_vulpes
ENSG00000135972	MRPS9	100	63.384	ENSXETG00000002583	mrps9	100	63.384	Xenopus_tropicalis
ENSG00000135972	MRPS9	86	60.526	ENSXCOG00000020462	mrps9	94	60.526	Xiphophorus_couchianus
ENSG00000135972	MRPS9	95	58.400	ENSXMAG00000007974	mrps9	98	58.400	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0005515	protein binding	22190034.	IPI	Function
GO:0005730	nucleolus	-	IDA	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005763	mitochondrial small ribosomal subunit	21873635.	IBA	Component
GO:0005763	mitochondrial small ribosomal subunit	-	ISS	Component
GO:0005763	mitochondrial small ribosomal subunit	11279123.	NAS	Component
GO:0042769	DNA damage response, detection of DNA damage	15300802.	NAS	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process