EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000136153 (Gene tree)
Gene ID: 4008
Gene Symbol: LMO7
Alias: FBX20|KIAA0858|FBXO20
Full Name: LIM domain 7
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 239,437 bases
Position: chr13:75,620,434-75,859,870
Accession: 6646
RBP type: non-canonical RBP
Summary: This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23921632	Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing.	Nucleic Acids Res	2013 Oct	Iwata Y	doi: 10.1093/nar/gkt667

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000532377	LMO7-221	595	-	-	- (aa)	-	-
ENST00000525373	LMO7-216	672	-	ENSP00000431896	191 (aa)	-	E9PJ10
ENST00000497947	LMO7-213	995	-	ENSP00000431271	121 (aa)	-	E9PLU6
ENST00000533809	LMO7-225	578	-	ENSP00000475811	99 (aa)	-	U3KQE6
ENST00000533305	LMO7-224	720	-	-	- (aa)	-	-
ENST00000465261	LMO7-207	5580	XM_017020589	ENSP00000433352	1385 (aa)	XP_016876078	A0A0A0MTE2
ENST00000526202	LMO7-218	4121	XM_024449354	ENSP00000431129	1275 (aa)	XP_024305122	E9PMS6
ENST00000534657	LMO7-226	589	-	ENSP00000434943	12 (aa)	-	E9PMJ6
ENST00000525914	LMO7-217	874	-	ENSP00000434083	292 (aa)	-	H0YDQ3
ENST00000533299	LMO7-223	1845	-	-	- (aa)	-	-
ENST00000467686	LMO7-209	591	-	-	- (aa)	-	-
ENST00000532785	LMO7-222	599	-	-	- (aa)	-	-
ENST00000482116	LMO7-210	935	-	-	- (aa)	-	-
ENST00000465309	LMO7-208	572	-	-	- (aa)	-	-
ENST00000321797	LMO7-201	5647	XM_017020574	ENSP00000317802	1398 (aa)	XP_016876063	E9PMT2
ENST00000489941	LMO7-212	597	-	ENSP00000431636	165 (aa)	-	E9PK58
ENST00000526371	LMO7-219	650	-	ENSP00000432269	165 (aa)	-	E9PRJ0
ENST00000485987	LMO7-211	1087	-	-	- (aa)	-	-
ENST00000377499	LMO7-204	3472	-	ENSP00000366719	1045 (aa)	-	E9PMP7
ENST00000605961	LMO7-227	2039	-	-	- (aa)	-	-
ENST00000526528	LMO7-220	572	-	ENSP00000434201	141 (aa)	-	E9PRE3
ENST00000357063	LMO7-203	8237	-	ENSP00000349571	1668 (aa)	-	J3KP06
ENST00000524651	LMO7-214	914	-	ENSP00000433591	305 (aa)	-	H0YDG6
ENST00000341547	LMO7-202	7237	XM_011535095	ENSP00000342112	1349 (aa)	XP_011533397	Q8WWI1
ENST00000525107	LMO7-215	536	-	ENSP00000435296	179 (aa)	-	H0YE95
ENST00000447038	LMO7-206	3165	-	ENSP00000388955	1055 (aa)	-	H0Y424
ENST00000377534	LMO7-205	4896	-	ENSP00000366757	1631 (aa)	-	F8WD26

Gene Model

Click here to download ENSG00000136153's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04520	Adherens junction	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000136153	Prostatic Neoplasms	2.5330000E-005	18264096
ENSG00000136153	Prostate-Specific Antigen	6.914e-005	-
ENSG00000136153	Prostate-Specific Antigen	6.914e-005	-
ENSG00000136153	Prostate-Specific Antigen	6.914e-005	-
ENSG00000136153	Prostate-Specific Antigen	5.464e-005	-
ENSG00000136153	Prostate-Specific Antigen	5.464e-005	-
ENSG00000136153	Waist Circumference	4.1300000E-005	-
ENSG00000136153	Waist Circumference	8.6850000E-005	-
ENSG00000136153	Waist Circumference	1.0000000E-004	-
ENSG00000136153	Astigmatism	4E-6	23761726
ENSG00000136153	Diabetes Mellitus, Type 1	6E-11	21980299

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000136153	rs111870938	13	75680572	C	Intraocular pressure	29617998	[0.074-0.13] unit decrease	0.102	EFO_0004695
ENSG00000136153	rs9544020	13	75679111	A	Intraocular pressure	29617998	[0.071-0.125] unit decrease	0.098	EFO_0004695
ENSG00000136153	rs11841001	13	75674967	A	Corneal astigmatism	23761726	[0.12-0.30] unit increase	0.208	HP_0000483
ENSG00000136153	rs9530458	13	75675139	T	Glaucoma (primary open-angle)	29449654	[1.11-1.19]	1.148	EFO_0004190
ENSG00000136153	rs76082815	13	75821206	T	Initial pursuit acceleration	29064472			EFO_0008434
ENSG00000136153	rs76082815	13	75821206	?	Initial pursuit acceleration in psychotic disorders	29064472			EFO_0000692\|EFO_0008434\|EFO_0000289\|EFO_0005411
ENSG00000136153	rs76082815	13	75821206	?	Initial pursuit acceleration in psychotic disorders	29064472			EFO_0000692\|EFO_0008434\|EFO_0000289\|EFO_0005411
ENSG00000136153	rs7338461	13	75671406	?	Intraocular pressure	30054594	[0.064-0.114] unit increase	0.0891	EFO_0004695
ENSG00000136153	rs3736858	13	75841243	G	Interleukin-9 levels	27989323	[0.08-0.195] SD units increase	0.1374	EFO_0008192
ENSG00000136153	rs539514	13	75752146	?	Type 1 diabetes	21980299	[NR]	1.43	EFO_0001359
ENSG00000136153	rs9544022	13	75683130	G	Intraocular pressure	29785010	[0.056-0.106] unit decrease	0.081	EFO_0004695
ENSG00000136153	rs75502311	13	75856884	?	Obsessive-compulsive disorder	30456828	[0.23-0.56] unit increase	0.397	EFO_0004242
ENSG00000136153	rs2224797	13	75636606	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000136153	rs2224797	13	75636606	?	Red blood cell count	30595370			EFO_0004305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000136153's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136153	LMO7	100	93.056	ENSMUSG00000033060	Lmo7	100	87.686	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000151	ubiquitin ligase complex	10531035.	NAS	Component
GO:0000209	protein polyubiquitination	-	TAS	Process
GO:0004842	ubiquitin-protein transferase activity	10531035.	NAS	Function
GO:0005634	nucleus	17067998.	IDA	Component
GO:0005635	nuclear envelope	17067998.	IDA	Component
GO:0005737	cytoplasm	17067998.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0009986	cell surface	17067998.	IDA	Component
GO:0016324	apical plasma membrane	-	ISS	Component
GO:0016567	protein ubiquitination	10531035.	NAS	Process
GO:0023051	regulation of signaling	-	IEA	Process
GO:0030155	regulation of cell adhesion	-	IEA	Process
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	17067998.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28026121	Circulating exosomal microRNA-96 promotes cell proliferation, migration and drug resistance by targeting LMO7.	J Cell Mol Med	2017 Jun	Wu H	doi: 10.1111/jcmm.13056

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr13	75834342	Missense_Mutation	novel	E828K	0.07
BLCA	chr13	75853363	Missense_Mutation	NA	Q1313K	0.25
BLCA	chr13	75823642	Silent	NA	A673A	0.19
BLCA	chr13	75835187	Intron	rs766126982		0.39
BLCA	chr13	75819408	Nonsense_Mutation	novel	K461*	0.04
BLCA	chr13	75841118	Missense_Mutation	novel	Q965E	0.15
BLCA	chr13	75835290	Missense_Mutation	novel	S862C	0.16
BLCA	chr13	75800725	5'UTR	novel		0.09
BLCA	chr13	75833089	Silent	novel	T763T	0.4
BLCA	chr13	75761020	5'UTR	NA		0.34
BLCA	chr13	75821424	Missense_Mutation	novel	E586K	0.24
BLCA	chr13	75834318	Missense_Mutation	NA	E820K	0.28
BLCA	chr13	75804493	Missense_Mutation	novel	R56K	0.31
BLCA	chr13	75853216	Nonsense_Mutation	novel	Q1264*	0.24
BLCA	chr13	75817266	Silent	novel	Q451Q	0.33
BLCA	chr13	75804314	5'UTR	novel		0.29
BLCA	chr13	75853096	Nonsense_Mutation	NA	E1224*	0.25
BLCA	chr13	75835333	Missense_Mutation	novel	Q876H	0.38
BLCA	chr13	75807558	Silent	novel	P192P	0.3
BRCA	chr13	75808054	Missense_Mutation	rs190179934	R358C	0.56
BRCA	chr13	75841774	Silent	novel	Q1041Q	0.08
BRCA	chr13	75821297	Missense_Mutation	novel	S543R	0.12
BRCA	chr13	75856562	Missense_Mutation	NA	S1340L	0.13
BRCA	chr13	75796647	5'UTR	rs758451086		0.44
BRCA	chr13	75858442	3'UTR	novel		0.36
BRCA	chr13	75841653	Missense_Mutation	NA	S1001N	0.39
CESC	chr13	75819456	Missense_Mutation	novel	E477Q	0.22
CESC	chr13	75821571	Missense_Mutation	novel	Q635E	0.18
CESC	chr13	75821569	Missense_Mutation	NA	S634F	0.11
CESC	chr13	75796715	5'UTR	novel		0.17
CESC	chr13	75800755	5'UTR	NA		0.25
CESC	chr13	75800820	5'UTR	NA		0.42
CESC	chr13	75821491	Nonsense_Mutation	NA	S608*	0.3
CESC	chr13	75841661	Missense_Mutation	NA	L1004V	0.35
CESC	chr13	75821397	Nonsense_Mutation	NA	Q577*	0.14
CESC	chr13	75805660	Missense_Mutation	NA	D133H	0.3
CESC	chr13	75840395	Missense_Mutation	rs776852274	P928L	0.5
COAD	chr13	75856609	Splice_Site	NA	X1355_splice	0.2
COAD	chr13	75841932	Missense_Mutation	rs148659145	R1094H	0.43
COAD	chr13	75760943	5'UTR	novel		0.46
COAD	chr13	75841149	Missense_Mutation	NA	W975L	0.12
COAD	chr13	75857786	Intron	novel		0.16
COAD	chr13	75800694	5'UTR	NA		0.37
COAD	chr13	75835185	Intron	NA		0.37
COAD	chr13	75760871	5'UTR	novel		0.25
COAD	chr13	75835338	Missense_Mutation	NA	S878Y	0.15
COAD	chr13	75836427	Missense_Mutation	NA	H889Y	0.18
COAD	chr13	75855356	Intron	novel		0.19
COAD	chr13	75808054	Missense_Mutation	rs190179934	R358C	0.37
COAD	chr13	75841828	Frame_Shift_Ins	NA	*K1064Gfs36**	0.33
COAD	chr13	75841820	Missense_Mutation	NA	L1057F	0.39
COAD	chr13	75858046	3'UTR	novel		0.18
COAD	chr13	75821258	Silent	NA	R530R	0.17
COAD	chr13	75855265	Intron	novel		0.38
COAD	chr13	75760898	5'UTR	novel		0.25
COAD	chr13	75823655	Missense_Mutation	rs370412695	A678T	0.28
COAD	chr13	75849234	Nonsense_Mutation	NA	R1203*	0.27
COAD	chr13	75821608	Missense_Mutation	rs774756205	T647M	0.06
COAD	chr13	75834351	Missense_Mutation	NA	H831Y	0.33
COAD	chr13	75841122	Missense_Mutation	NA	R966H	0.32
COAD	chr13	75807821	Frame_Shift_Del	novel	*D282Mfs3**	0.16
COAD	chr13	75808187	Missense_Mutation	novel	L402R	0.09
COAD	chr13	75858202	3'UTR	novel		0.23
COAD	chr13	75841155	Missense_Mutation	NA	R977M	0.44
COAD	chr13	75853143	Silent	NA	Q1239Q	0.15
COAD	chr13	75808092	Silent	NA	P370P	0.23
COAD	chr13	75821380	Missense_Mutation	rs760259550	R571H	0.21
COAD	chr13	75841828	Frame_Shift_Ins	NA	*K1064Gfs36**	0.24
COAD	chr13	75800876	5'UTR	rs775510856		0.41
COAD	chr13	75834372	Missense_Mutation	rs369234596	R838C	0.4
COAD	chr13	75849202	Missense_Mutation	NA	R1192I	0.2
COAD	chr13	75807587	Missense_Mutation	NA	R202M	0.19
COAD	chr13	75821380	Missense_Mutation	rs760259550	R571H	0.28
COAD	chr13	75857757	Intron	rs111294296		0.5
COAD	chr13	75760940	5'UTR	NA		0.26
COAD	chr13	75804391	Missense_Mutation	rs375314137	A22V	0.28
COAD	chr13	75807953	Missense_Mutation	NA	F324C	0.3
COAD	chr13	75819418	Missense_Mutation	rs372334697	R464Q	0.25
COAD	chr13	75805619	Missense_Mutation	NA	R119H	0.38
COAD	chr13	75833146	Silent	NA	F782F	0.33
COAD	chr13	75840097	Missense_Mutation	rs766012567	S922L	0.37
COAD	chr13	75853327	Missense_Mutation	novel	S1301P	0.15
ESCA	chr13	75800726	5'UTR	novel		0.27
ESCA	chr13	75840416	Missense_Mutation	rs774048028	P935L	0.11
ESCA	chr13	75823651	Silent	NA	P676P	0.2
ESCA	chr13	75849189	Missense_Mutation	novel	E1188K	0.14
ESCA	chr13	75807484	Missense_Mutation	novel	F168I	0.62
ESCA	chr13	75849241	Missense_Mutation	rs185108401	R1205H	0.58
ESCA	chr13	75823837	Silent	novel	G738G	0.31
GBM	chr13	75807718	Nonsense_Mutation	NA	R246*	0.57
GBM	chr13	75761025	5'UTR	rs759055579		0.16
GBM	chr13	75841627	Splice_Site	novel	X993_splice	0.51
GBM	chr13	75808080	Silent	rs753994039	G366G	0.15
GBM	chr13	75807944	Missense_Mutation	novel	Q321P	0.05
GBM	chr13	75841931	Missense_Mutation	rs144089219	R1094C	0.25
GBM	chr13	75807823	Missense_Mutation	novel	K281Q	0.11
GBM	chr13	75800734	5'UTR	rs41286124		0.44
HNSC	chr13	75821335	Missense_Mutation	novel	E556G	0.29
HNSC	chr13	75821194	Missense_Mutation	novel	K509T	0.4
HNSC	chr13	75823870	Silent	novel	S749S	0.37
HNSC	chr13	75819511	Missense_Mutation	rs763725582	T495M	0.31
HNSC	chr13	75845340	Missense_Mutation	novel	S1138P	0.25
HNSC	chr13	75807765	Silent	novel	V261V	0.34
HNSC	chr13	75853358	Missense_Mutation	novel	A1311D	0.53
HNSC	chr13	75808109	Missense_Mutation	novel	P376R	0.31
KIRC	chr13	75795425	5'UTR	NA		0.27
KIRC	chr13	75856577	Missense_Mutation	NA	C1345Y	0.28
KIRC	chr13	75858157	3'UTR	novel		0.31
KIRC	chr13	75807654	Frame_Shift_Ins	novel	*L225Ffs4**	0.2
KIRC	chr13	75760935	5'UTR	NA		0.38
KIRP	chr13	75821343	Frame_Shift_Del	novel	*K559Lfs8**	0.32
KIRP	chr13	75853351	Missense_Mutation	novel	P1309S	0.36
KIRP	chr13	75804453	Missense_Mutation	novel	L43M	0.39
KIRP	chr13	75807674	Missense_Mutation	novel	F231C	0.27
LAML	chr13	75823597	Silent	novel	V658V	0.05
LAML	chr13	75841924	Silent	novel	E1091E	0.04
LAML	chr13	75833138	Missense_Mutation	novel	G780R	0.04
LGG	chr13	75821379	Missense_Mutation	rs775970006	R571C	0.22
LGG	chr13	75835189	Intron	novel		0.37
LGG	chr13	75841880	Missense_Mutation	rs768424294	R1077W	0.36
LGG	chr13	75853338	Silent	rs776487535	P1304P	0.38
LGG	chr13	75808079	Missense_Mutation	NA	G366E	0.31
LIHC	chr13	75807560	Missense_Mutation	NA	T193N	0.48
LIHC	chr13	75823826	Missense_Mutation	NA	S735A	0.24
LIHC	chr13	75855340	Intron	NA		0.29
LIHC	chr13	75807959	Missense_Mutation	NA	C326Y	0.16
LIHC	chr13	75807730	Missense_Mutation	novel	D250N	0.05
LIHC	chr13	75823714	Missense_Mutation	novel	D697E	0.52
LUAD	chr13	75835283	Missense_Mutation	novel	E860K	0.07
LUAD	chr13	75849196	Missense_Mutation	novel	R1190M	0.16
LUAD	chr13	75823766	Nonsense_Mutation	NA	Q715*	0.22
LUAD	chr13	75853369	Missense_Mutation	NA	G1315C	0.22
LUAD	chr13	75857999	Missense_Mutation	novel	H1382Y	0.26
LUAD	chr13	75807664	Missense_Mutation	novel	D228N	0.06
LUAD	chr13	75808144	Missense_Mutation	NA	E388K	0.12
LUAD	chr13	75819524	Missense_Mutation	novel	M499I	0.41
LUAD	chr13	75805569	Missense_Mutation	NA	K102N	0.11
LUAD	chr13	75855287	Intron	novel		0.15
LUAD	chr13	75821280	Missense_Mutation	NA	E538Q	0.1
LUAD	chr13	75856543	Nonsense_Mutation	NA	Q1334*	0.17
LUAD	chr13	75807499	Missense_Mutation	novel	A173P	0.43
LUAD	chr13	75840426	Missense_Mutation	novel	W938C	0.23
LUAD	chr13	75821195	Missense_Mutation	novel	K509N	0.39
LUAD	chr13	75800820	5'UTR	novel		0.41
LUAD	chr13	75821548	Missense_Mutation	novel	V627G	0.39
LUAD	chr13	75841665	Missense_Mutation	novel	T1005N	0.07
LUAD	chr13	75853096	Missense_Mutation	rs774848818	E1224K	0.15
LUSC	chr13	75800730	5'UTR	novel		0.21
LUSC	chr13	75804480	Missense_Mutation	novel	E52K	0.13
LUSC	chr13	75836424	Frame_Shift_Del	novel	*I888Mfs17**	0.04
LUSC	chr13	75857948	Missense_Mutation	NA	S1365C	0.43
LUSC	chr13	75808146	Missense_Mutation	NA	E388D	0.49
LUSC	chr13	75834308	Silent	NA	S816S	0.19
LUSC	chr13	75804431	Silent	novel	Q35Q	0.16
LUSC	chr13	75833105	Missense_Mutation	novel	D769H	0.1
LUSC	chr13	75857838	Intron	novel		0.11
LUSC	chr13	75853090	Splice_Site	NA	X1222_splice	0.27
LUSC	chr13	75804437	Frame_Shift_Ins	novel	*Y38Ifs15**	0.07
LUSC	chr13	75804438	Frame_Shift_Ins	novel	*Y38Sfs17**	0.08
LUSC	chr13	75833120	Missense_Mutation	NA	I774V	0.42
LUSC	chr13	75841159	Silent	rs762082667	A978A	0.79
LUSC	chr13	75855330	Intron	novel		0.27
LUSC	chr13	75856540	Missense_Mutation	novel	P1333T	0.23
LUSC	chr13	75833138	Missense_Mutation	novel	G780W	0.23
LUSC	chr13	75841778	Nonsense_Mutation	NA	E1043*	0.35
LUSC	chr13	75853143	Missense_Mutation	novel	Q1239H	0.22
LUSC	chr13	75855317	Intron	rs763979347		0.23
OV	chr13	75823745	Missense_Mutation	novel	F708I	0.14
OV	chr13	75835315	Missense_Mutation	NA	D870E	0.33
OV	chr13	75805623	Missense_Mutation	novel	K120N	0.05
OV	chr13	75821380	Missense_Mutation	rs760259550	R571H	0.21
OV	chr13	75804473	Missense_Mutation	novel	D49E	0.09
OV	chr13	75761018	5'UTR	novel		0.13
OV	chr13	75856567	Frame_Shift_Ins	novel	*T1343Hfs21**	0.01
PAAD	chr13	75795421	5'UTR	novel		0.15
PAAD	chr13	75805690	Missense_Mutation	novel	E143K	0.16
PAAD	chr13	75821535	Silent	novel	L623L	0.05
PAAD	chr13	75855340	Intron	NA		0.18
PRAD	chr13	75800856	5'UTR	NA		0.05
READ	chr13	75800690	5'UTR	rs200309758		0.23
READ	chr13	75821257	Missense_Mutation	rs558204044	R530Q	0.38
READ	chr13	75823592	Missense_Mutation	NA	D657N	0.33
READ	chr13	75834335	Missense_Mutation	NA	K825N	0.74
READ	chr13	75760964	5'UTR	novel		0.06
READ	chr13	75853119	Silent	rs779068382	S1231S	0.15
READ	chr13	75800793	5'UTR	novel		0.42
READ	chr13	75805587	Missense_Mutation	NA	I108M	0.08
READ	chr13	75856635	Intron	rs751806147		0.42
READ	chr13	75857958	Missense_Mutation	rs376296039	T1368M	0.43
READ	chr13	75800762	5'UTR	NA		0.29
READ	chr13	75835322	Missense_Mutation	rs377551293	E873K	0.23
SARC	chr13	75821517	Nonsense_Mutation	novel	K617*	0.77
SARC	chr13	75833129	Missense_Mutation	novel	D777N	0.2
SARC	chr13	75800850	5'UTR	novel		0.24
SARC	chr13	75800851	5'UTR	novel		0.24
SKCM	chr13	75821182	Missense_Mutation	novel	S505F	0.33
SKCM	chr13	75800735	5'UTR	rs774821080		0.52
SKCM	chr13	75823636	Silent	novel	T671T	0.43
SKCM	chr13	75821316	Missense_Mutation	rs757559296	G550R	0.41
SKCM	chr13	75800802	5'UTR	NA		0.25
SKCM	chr13	75807845	Missense_Mutation	rs747051266	R288Q	0.44
SKCM	chr13	75808022	Missense_Mutation	novel	S347L	0.58
SKCM	chr13	75840404	Missense_Mutation	novel	T931I	0.13
SKCM	chr13	75841743	Missense_Mutation	rs775620229	R1031Q	0.42
SKCM	chr13	75807556	Missense_Mutation	novel	P192S	0.07
SKCM	chr13	75807845	Missense_Mutation	rs747051266	R288Q	0.08
SKCM	chr13	75838176	Missense_Mutation	rs760433267	R911Q	0.19
SKCM	chr13	75840436	Nonsense_Mutation	NA	Q942*	0.33
SKCM	chr13	75842906	Missense_Mutation	NA	P1130S	0.28
SKCM	chr13	75853338	Silent	rs776487535	P1304P	0.19
SKCM	chr13	75841810	Silent	rs149629426	P1053P	0.34
SKCM	chr13	75823579	Nonsense_Mutation	novel	W652*	0.37
SKCM	chr13	75853309	Missense_Mutation	novel	G1295S	0.24
SKCM	chr13	75853310	Missense_Mutation	novel	G1295D	0.24
SKCM	chr13	75819460	Missense_Mutation	NA	R478K	0.11
SKCM	chr13	75807820	Missense_Mutation	NA	E280K	0.12
SKCM	chr13	75823798	Silent	NA	S725S	0.41
SKCM	chr13	75833135	Missense_Mutation	NA	P779S	0.17
SKCM	chr13	75853321	Missense_Mutation	novel	T1299A	0.28
SKCM	chr13	75807584	Missense_Mutation	rs372308172	R201H	0.22
SKCM	chr13	75842895	Missense_Mutation	NA	S1126L	0.08
SKCM	chr13	75849276	Missense_Mutation	rs749328214	P1217S	0.24
SKCM	chr13	75858073	3'UTR	novel		0.2
SKCM	chr13	75819418	Missense_Mutation	rs372334697	R464Q	0.43
SKCM	chr13	75853133	Missense_Mutation	NA	S1236F	0.09
SKCM	chr13	75857959	Silent	novel	T1368T	0.86
SKCM	chr13	75849182	Silent	NA	I1185I	0.34
SKCM	chr13	75821502	Missense_Mutation	rs773245524	P612S	0.98
SKCM	chr13	75834303	Missense_Mutation	rs556560630	D815N	0.34
SKCM	chr13	75841942	Silent	novel	E1097E	0.41
SKCM	chr13	75834339	Nonsense_Mutation	rs750206625	Q827*	0.1
SKCM	chr13	75841870	Silent	NA	Q1073Q	0.41
SKCM	chr13	75841159	Silent	rs762082667	A978A	0.38
SKCM	chr13	75807865	Missense_Mutation	NA	E295K	0.17
SKCM	chr13	75841811	Missense_Mutation	NA	Q1054E	0.21
SKCM	chr13	75853262	Missense_Mutation	novel	S1279F	0.24
SKCM	chr13	75821329	Missense_Mutation	NA	P554L	0.4
SKCM	chr13	75807913	Missense_Mutation	NA	P311S	0.27
SKCM	chr13	75800722	5'UTR	rs756480889		0.08
SKCM	chr13	75857959	Silent	novel	T1368T	0.26
SKCM	chr13	75817255	Missense_Mutation	NA	E448K	0.32
SKCM	chr13	75808139	Missense_Mutation	NA	R386K	0.58
SKCM	chr13	75808114	Missense_Mutation	NA	P378S	0.14
SKCM	chr13	75807754	Missense_Mutation	NA	D258N	0.37
SKCM	chr13	75807821	Missense_Mutation	NA	E280A	0.46
SKCM	chr13	75849189	Nonsense_Mutation	NA	E1188*	0.25
SKCM	chr13	75760927	5'UTR	novel		0.39
SKCM	chr13	75841800	Missense_Mutation	NA	G1050E	0.36
SKCM	chr13	75821174	Splice_Region	novel		0.27
SKCM	chr13	75821235	Missense_Mutation	NA	D523N	0.27
STAD	chr13	75800701	5'UTR	novel		0.09
STAD	chr13	75823739	Missense_Mutation	novel	S706P	0.14
STAD	chr13	75857926	Silent	rs199772213	D1357D	0.18
STAD	chr13	75842876	Missense_Mutation	NA	K1120E	0.31
STAD	chr13	75807909	Silent	rs779966190	P309P	0.3
STAD	chr13	75804479	Silent	NA	H51H	0.28
STAD	chr13	75841931	Missense_Mutation	rs144089219	R1094C	0.19
STAD	chr13	75823654	Silent	rs377226161	D677D	0.2
STAD	chr13	75819414	Missense_Mutation	rs749357751	R463C	0.37
STAD	chr13	75804490	Missense_Mutation	novel	R55I	0.27
STAD	chr13	75808163	Missense_Mutation	novel	S394N	0.33
STAD	chr13	75834337	Missense_Mutation	NA	A826V	0.08
STAD	chr13	75833050	Splice_Site	NA	X751_splice	0.11
STAD	chr13	75807654	Silent	NA	D224D	0.2
STAD	chr13	75804289	Splice_Region	novel		0.19
STAD	chr13	75849210	Frame_Shift_Ins	novel	*L1195Hfs4**	0.26
STAD	chr13	75804314	5'UTR	novel		0.18
STAD	chr13	75808029	Silent	NA	R349R	0.19
STAD	chr13	75834289	Missense_Mutation	rs761122156	K810R	0.31
STAD	chr13	75855276	Intron	NA		0.16
STAD	chr13	75834225	Splice_Site	novel	X789_splice	0.09
STAD	chr13	75819419	Frame_Shift_Del	rs34219193	*S466Vfs69**	0.29
STAD	chr13	75804391	Missense_Mutation	rs375314137	A22V	0.3
STAD	chr13	75857927	Missense_Mutation	NA	G1358S	0.28
STAD	chr13	75842852	Missense_Mutation	NA	P1112T	0.08
STAD	chr13	75853257	Silent	novel	P1277P	0.21
STAD	chr13	75807909	Frame_Shift_Del	novel	*E312Nfs33**	0.35
STAD	chr13	75853251	Silent	NA	R1275R	0.13
STAD	chr13	75833116	Silent	NA	F772F	0.18
STAD	chr13	75823655	Missense_Mutation	rs370412695	A678T	0.23
STAD	chr13	75805618	Missense_Mutation	rs760920054	R119C	0.21
STAD	chr13	75817272	Nonsense_Mutation	NA	W453*	0.27
STAD	chr13	75834373	Missense_Mutation	rs747794496	R838H	0.08
THCA	chr13	75853203	Missense_Mutation	novel	S1259R	0.39
THYM	chr13	75761009	5'UTR	rs369873212		0.09
UCEC	chr13	75858046	3'UTR	rs532445404		0.47
UCEC	chr13	75804436	Missense_Mutation	novel	S37C	0.11
UCEC	chr13	75835335	Missense_Mutation	novel	S877I	0.35
UCEC	chr13	75804360	Nonsense_Mutation	NA	R12*	0.33
UCEC	chr13	75800829	5'UTR	rs763453988		0.27
UCEC	chr13	75804466	Missense_Mutation	NA	K47T	0.3
UCEC	chr13	75807584	Missense_Mutation	rs372308172	R201H	0.28
UCEC	chr13	75838176	Missense_Mutation	rs760433267	R911Q	0.24
UCEC	chr13	75858218	3'UTR	rs552715869		0.16
UCEC	chr13	75805512	Missense_Mutation	NA	E83D	0.15
UCEC	chr13	75807841	Missense_Mutation	rs758569680	R287C	0.36
UCEC	chr13	75809165	Missense_Mutation	NA	K410R	0.36
UCEC	chr13	75819417	Nonsense_Mutation	NA	R464*	0.26
UCEC	chr13	75833135	Missense_Mutation	NA	P779T	0.17
UCEC	chr13	75800755	5'UTR	novel		0.41
UCEC	chr13	75821585	Silent	novel	I639I	0.45
UCEC	chr13	75840414	Silent	novel	A934A	0.52
UCEC	chr13	75858061	3'UTR	rs764852317		0.51
UCEC	chr13	75808064	Missense_Mutation	novel	Q361L	0.25
UCEC	chr13	75807988	Nonsense_Mutation	NA	E336*	0.4
UCEC	chr13	75808179	Silent	NA	K399K	0.43
UCEC	chr13	75858218	3'UTR	rs552715869		0.33
UCEC	chr13	75805709	Missense_Mutation	novel	R149I	0.16
UCEC	chr13	75857743	Intron	novel		0.37
UCEC	chr13	75834303	Missense_Mutation	rs556560630	D815N	0.52
UCEC	chr13	75858215	3'UTR	novel		0.37
UCEC	chr13	75858661	3'UTR	novel		0.28
UCEC	chr13	75760856	5'UTR	novel		0.37
UCEC	chr13	75804311	5'UTR	rs75569760		0.4
UCEC	chr13	75858291	3'UTR	novel		0.46
UCEC	chr13	75853149	Silent	novel	P1241P	0.38
UCEC	chr13	75853269	Silent	novel	V1281V	0.79
UCEC	chr13	75821569	Missense_Mutation	NA	S634Y	0.13
UCEC	chr13	75857908	Intron	novel		0.06
UCEC	chr13	75808117	Missense_Mutation	NA	C379R	0.39
UCEC	chr13	75804355	Missense_Mutation	rs371465917	S10L	0.23
UCEC	chr13	75807692	Missense_Mutation	NA	A237V	0.18
UCEC	chr13	75833147	Missense_Mutation	rs139666814	V783I	0.22
UCEC	chr13	75840096	Missense_Mutation	novel	S922P	0.09
UCEC	chr13	75849281	Silent	NA	G1218G	0.26
UCEC	chr13	75817207	Missense_Mutation	rs370187434	R432C	0.37
UCEC	chr13	75841764	Missense_Mutation	NA	R1038K	0.32
UCEC	chr13	75804432	Missense_Mutation	novel	P36T	0.19
UCEC	chr13	75823727	Missense_Mutation	NA	P702S	0.22
UCEC	chr13	75760778	5'UTR	novel		0.4
UCEC	chr13	75823651	Silent	NA	P676P	0.45
UCEC	chr13	75857792	Intron	novel		0.36
UCEC	chr13	75858029	3'UTR	novel		0.13
UCEC	chr13	75760838	5'UTR	novel		0.33
UCEC	chr13	75819436	Missense_Mutation	novel	D470G	0.35
UCEC	chr13	75857864	Intron	novel		0.2
UCEC	chr13	75795425	5'UTR	novel		0.25
UCEC	chr13	75821599	Missense_Mutation	novel	R644I	0.38
UCEC	chr13	75841670	Missense_Mutation	rs202190221	R1007W	0.38
UCEC	chr13	75835213	Intron	novel		0.2
UCEC	chr13	75819453	Nonsense_Mutation	novel	E476*	0.41
UCEC	chr13	75858614	3'UTR	novel		0.26
UCEC	chr13	75800849	5'UTR	rs369370057		0.32
UCEC	chr13	75817216	Missense_Mutation	rs147322352	R435C	0.32
UCEC	chr13	75823781	Missense_Mutation	novel	K720E	0.42
UCEC	chr13	75835327	Silent	novel	S874S	0.35
UCEC	chr13	75841108	Splice_Site	novel	X962_splice	0.39
UCEC	chr13	75853195	Missense_Mutation	novel	D1257Y	0.32
UCEC	chr13	75858157	3'UTR	novel		0.49
UCEC	chr13	75858046	3'UTR	rs532445404		0.38
UCEC	chr13	75800869	5'UTR	novel		0.42
UCEC	chr13	75858218	3'UTR	rs552715869		0.49
UCEC	chr13	75858029	3'UTR	novel		0.23
UCEC	chr13	75819418	Missense_Mutation	rs372334697	R464Q	0.41
UCEC	chr13	75808078	Missense_Mutation	novel	G366R	0.34
UCEC	chr13	75821548	Missense_Mutation	novel	V627A	0.29
UCEC	chr13	75807884	Frame_Shift_Del	novel	*P302Qfs43**	0.45
UCEC	chr13	75853262	Frame_Shift_Ins	novel	*S1280Vfs49**	0.11
UCEC	chr13	75835298	Silent	novel	L865L	0.18
UCEC	chr13	75857935	Silent	rs372811162	P1360P	0.26
UCEC	chr13	75819467	Missense_Mutation	novel	E480D	0.41
UCEC	chr13	75800774	5'UTR	novel		0.44
UCEC	chr13	75834237	Nonsense_Mutation	novel	E793*	0.4
UCEC	chr13	75857958	Missense_Mutation	rs376296039	T1368M	0.4
UCEC	chr13	75821461	Missense_Mutation	novel	R598Q	0.24
UCEC	chr13	75858000	Missense_Mutation	novel	H1382L	0.34
UCEC	chr13	75835321	Silent	rs762956632	S872S	0.17
UCEC	chr13	75855316	Intron	novel		0.34
UCEC	chr13	75858139	3'UTR	novel		0.22
UCEC	chr13	75807580	Missense_Mutation	novel	T200P	0.12
UCEC	chr13	75853213	Missense_Mutation	novel	P1263A	0.35
UCEC	chr13	75821455	Missense_Mutation	rs753624038	R596H	0.24
UCEC	chr13	75840456	Silent	novel	R948R	0.56
UCEC	chr13	75819446	Frame_Shift_Ins	NA	*E476Rfs7**	0.45
UCEC	chr13	75841671	Missense_Mutation	rs772131674	R1007Q	0.41
UCEC	chr13	75823654	Silent	rs377226161	D677D	0.4
UCEC	chr13	75858150	3'UTR	novel		0.32
UCEC	chr13	75760826	5'UTR	novel		0.08
UCEC	chr13	75817207	Missense_Mutation	rs370187434	R432C	0.31
UCEC	chr13	75857935	Silent	rs372811162	P1360P	0.21
UCEC	chr13	75804321	5'UTR	novel		0.36
UCEC	chr13	75858062	3'UTR	novel		0.39
UCEC	chr13	75833139	In_Frame_Ins	novel	G780_I781insQGRGNPFAEVL	0.06
UCEC	chr13	75834254	Missense_Mutation	novel	Q798H	0.33
UCEC	chr13	75857851	Intron	novel		0.49
UCEC	chr13	75800690	5'UTR	rs200309758		0.67
UCEC	chr13	75807549	Missense_Mutation	NA	K189N	0.51
UCEC	chr13	75821346	Missense_Mutation	NA	E560K	0.33
UCEC	chr13	75835286	Missense_Mutation	NA	K861Q	0.51
UCEC	chr13	75804311	5'UTR	rs75569760		0.44
UCEC	chr13	75805552	Missense_Mutation	NA	Y97D	0.3
UCEC	chr13	75807492	Nonsense_Mutation	novel	L171*	0.1
UCEC	chr13	75821423	Nonsense_Mutation	novel	E585_E586ins*	0.13
UCEC	chr13	75821424	Frame_Shift_Ins	novel	*E586Dfs40**	0.09
UCEC	chr13	75853262	Frame_Shift_Ins	novel	*S1280Vfs49**	0.07
UCEC	chr13	75807584	Missense_Mutation	rs372308172	R201H	0.3
UCEC	chr13	75819479	Missense_Mutation	novel	Q484H	0.27
UCEC	chr13	75821178	Missense_Mutation	novel	E504K	0.22
UCEC	chr13	75856832	Intron	novel		0.6
UCEC	chr13	75857935	Silent	rs372811162	P1360P	0.25
UCEC	chr13	75858219	3'UTR	novel		0.49
UCEC	chr13	75853262	In_Frame_Ins	novel	S1279_S1280insVFLSSHRLH	0.05
UCEC	chr13	75804370	Missense_Mutation	rs375012849	S15L	0.57
UCEC	chr13	75821566	Missense_Mutation	NA	G633V	0.34
UCEC	chr13	75800870	5'UTR	novel		0.34
UCEC	chr13	75858298	3'UTR	novel		0.23
UCEC	chr13	75800830	5'UTR	rs751065469		0.54
UCEC	chr13	75807842	Missense_Mutation	novel	R287H	0.68
UCEC	chr13	75834330	Missense_Mutation	novel	A824T	0.45
UCEC	chr13	75855318	Intron	rs776990229		0.21

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.4167	0.076931
GBM	DEL	0.3449	4.92e-12
PRAD	DEL	0.2907	1.7107e-36

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.00011	Kaplan-Meier Survival Analysis
LUSC	0.045	Kaplan-Meier Survival Analysis
ESCA	0.037	Kaplan-Meier Survival Analysis
KIRP	0.0077	Kaplan-Meier Survival Analysis
PAAD	0.00012	Kaplan-Meier Survival Analysis
LAML	0.022	Kaplan-Meier Survival Analysis
UCEC	0.0011	Kaplan-Meier Survival Analysis
GBM	0.012	Kaplan-Meier Survival Analysis
LIHC	0.031	Kaplan-Meier Survival Analysis
DLBC	0.049	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
OV	0.041	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742