EuRBPDB

Description

Ensembl ID: ENSG00000136243 (Gene tree)
Gene ID: 11097
Gene Symbol: NUPL2
Alias: NLP_1|CG1|hCG1|H_RG271G13.9
Full Name: nucleoporin like 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 19,185 bases
Position: chr7:23,181,827-23,201,011
Accession: 17010
RBP type: non-canonical RBP
Summary: (Nucleoporin 42) is a Protein Coding gene. Among its related pathways are Transport of Mature Transcript to Cytoplasm and Transport of the SLBP independent Mature mRNA. An important paralog of this gene is LENG9.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000477844	NUPL2-206	2529	-	-	- (aa)	-	-
ENST00000438012	NUPL2-205	1653	-	ENSP00000415511	224 (aa)	-	O15504
ENST00000497500	NUPL2-211	739	-	-	- (aa)	-	-
ENST00000485250	NUPL2-207	2010	-	-	- (aa)	-	-
ENST00000489145	NUPL2-210	776	-	-	- (aa)	-	-
ENST00000410002	NUPL2-202	680	-	ENSP00000387330	155 (aa)	-	B4DT96
ENST00000486136	NUPL2-208	350	-	-	- (aa)	-	-
ENST00000437140	NUPL2-204	1285	-	ENSP00000406677	44 (aa)	-	F8WC66
ENST00000258742	NUPL2-201	1795	XM_017011714	ENSP00000258742	423 (aa)	XP_016867203	O15504
ENST00000548367	NUPL2-212	249	-	ENSP00000482736	83 (aa)	-	A0A087WZL5
ENST00000413919	NUPL2-203	1329	XM_005249592	ENSP00000401475	435 (aa)	XP_005249649	C9JYA1
ENST00000487595	NUPL2-209	623	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000136243	Pulmonary Disease, Chronic Obstructive	6E-8	25584925

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136243	NUPL2	96	84.106	ENSMUSG00000048439	Nupl2	93	84.106	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005049	nuclear export signal receptor activity	21873635.	IBA	Function
GO:0005049	nuclear export signal receptor activity	10358091.	IDA	Function
GO:0005515	protein binding	10358091.22250199.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	10358091.22250199.	IDA	Component
GO:0005635	nuclear envelope	21873635.	IBA	Component
GO:0005635	nuclear envelope	22250199.	IDA	Component
GO:0005643	nuclear pore	-	IEA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006110	regulation of glycolytic process	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006409	tRNA export from nucleus	-	TAS	Process
GO:0006611	protein export from nucleus	22250199.	IGI	Process
GO:0016032	viral process	-	TAS	Process
GO:0016925	protein sumoylation	-	TAS	Process
GO:0019083	viral transcription	-	TAS	Process
GO:0031965	nuclear membrane	-	IEA	Component
GO:0043657	host cell	-	IEA	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process
GO:0075733	intracellular transport of virus	-	TAS	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process