EuRBPDB

Description

Ensembl ID: ENSG00000136463 (Gene tree)
Gene ID: 51204
Gene Symbol: TACO1
Alias: CCDC44
Full Name: translational activator of cytochrome c oxidase I
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 7,494 bases
Position: chr17:63,600,872-63,608,365
Accession: 24316
RBP type: non-canonical RBP
Summary: This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27319982	Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice.	Nat Commun	2016 Jun 20	Richman TR	doi: 10.1038/ncomms11884.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000581120	TACO1-202	2304	-	-	- (aa)	-	-
ENST00000258975	TACO1-201	1469	-	ENSP00000258975	297 (aa)	-	Q9BSH4

Gene Model

Protein-Protein Interaction (PPI)

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136463	TACO1	100	77.778	ENSMUSG00000001983	Taco1	95	79.078	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16189514.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0006417	regulation of translation	-	IEA	Process