EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000136628 (Gene tree)
Gene ID: 2058
Gene Symbol: EPRS
Alias: EARS|PARS|GLUPRORS|QPRS|QARS
Full Name: glutamyl-prolyl-tRNA synthetase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 78,059 bases
Position: chr1:219,968,600-220,046,658
Accession: 3418
RBP type: canonical RBP
Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000477245	tRNA-synt_1c_C	PF03950.18	7.5e-39	1	1
ENSP00000355890	tRNA-synt_1c_C	PF03950.18	3.4e-38	1	1
ENSP00000355890	HGTP_anticodon	PF03129.20	3.7e-16	1	1
ENSP00000355890	tRNA-synt_1c	PF00749.21	8.5e-125	1	1
ENSP00000477245	tRNA-synt_1c	PF00749.21	4.1e-124	1	1
ENSP00000355890	tRNA-synt_2b	PF00587.25	7.9e-17	1	1
ENSP00000355890	ProRS-C_1	PF09180.11	1.5e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23362130	Amino acid-selective segmental isotope labeling of multidomain proteins for structural biology.	Chembiochem	2013 Mar 4	Michel E	doi: 10.1002/cbic.201200732
10654942	A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.	EMBO J	2000 Feb 1	Cahuzac B	-
19535251	The GAIT system: a gatekeeper of inflammatory gene expression.	Trends Biochem Sci	2009 Jul	Mukhopadhyay R	doi: 10.1016/j.tibs.2009.03.004
11123902	Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.	Biochemistry	2000 Dec 26	Jeong EJ	-
20829344	Evolution of function of a fused metazoan tRNA synthetase.	Mol Biol Evol	2011 Jan	Ray PS	doi: 10.1093/molbev/msq246
11054821	Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5.	Yeast	2000 Nov	Xiang Z	-
18374644	WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression.	Mol Cell	2008 Mar 28	Jia J	doi: 10.1016/j.molcel.2008.01.010.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000485821	EPRS-205	598	-	-	- (aa)	-	-
ENST00000366923	EPRS-201	5014	XM_017000614	ENSP00000355890	1512 (aa)	XP_016856103	P07814
ENST00000464052	EPRS-202	770	-	-	- (aa)	-	-
ENST00000609181	EPRS-206	2968	-	ENSP00000477245	968 (aa)	-	V9GYZ6
ENST00000468487	EPRS-203	458	-	-	- (aa)	-	-
ENST00000477030	EPRS-204	1526	-	ENSP00000477493	194 (aa)	-	V9GZ76

Gene Model

Click here to download ENSG00000136628's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00860	Porphyrin and chlorophyll metabolism	KEGG
hsa00970	Aminoacyl-tRNA biosynthesis	KEGG
hsa01100	Metabolic pathways	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000136628	Hip	7.65346517689356E-5	17903296

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000136628	rs11325774	1	220015795	T	High light scatter reticulocyte percentage of red cells	27863252	[0.033-0.051] unit increase	0.04187391	EFO_0007986
ENSG00000136628	rs11325774	1	220015795	T	Immature fraction of reticulocytes	27863252	[0.028-0.046] unit increase	0.0366589	EFO_0007986
ENSG00000136628	rs11325774	1	220015795	T	High light scatter reticulocyte count	27863252	[0.031-0.049] unit increase	0.04020575	EFO_0007986
ENSG00000136628	rs2647462	1	219982748	T	Heel bone mineral density	30598549	[0.029-0.039] unit increase	0.0340613	EFO_0009270
ENSG00000136628	rs2795315	1	219972029	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000136628's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000136628	EPRS	53	33.955	ENSG00000172053	QARS	98	42.857

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136628	EPRS	99	69.987	ENSAPOG00000002084	eprs	99	69.914	Acanthochromis_polyacanthus
ENSG00000136628	EPRS	100	85.047	ENSAMEG00000009983	EPRS	100	85.047	Ailuropoda_melanoleuca
ENSG00000136628	EPRS	98	71.659	ENSACIG00000007907	eprs	100	71.419	Amphilophus_citrinellus
ENSG00000136628	EPRS	99	71.486	ENSAOCG00000023555	eprs	98	71.096	Amphiprion_ocellaris
ENSG00000136628	EPRS	99	70.152	ENSAPEG00000001630	eprs	99	69.835	Amphiprion_percula
ENSG00000136628	EPRS	99	70.164	ENSATEG00000006493	eprs	99	68.646	Anabas_testudineus
ENSG00000136628	EPRS	100	73.429	ENSAPLG00000003240	EPRS	100	78.365	Anas_platyrhynchos
ENSG00000136628	EPRS	99	81.537	ENSACAG00000001213	EPRS	99	81.340	Anolis_carolinensis
ENSG00000136628	EPRS	100	96.694	ENSANAG00000022208	EPRS	97	97.647	Aotus_nancymaae
ENSG00000136628	EPRS	99	70.633	ENSACLG00000020228	eprs	100	69.797	Astatotilapia_calliptera
ENSG00000136628	EPRS	99	70.205	ENSAMXG00000001984	eprs	99	68.724	Astyanax_mexicanus
ENSG00000136628	EPRS	100	92.526	ENSBTAG00000006898	EPRS	100	92.526	Bos_taurus
ENSG00000136628	EPRS	99	47.988	WBGene00001337	ears-1	98	48.956	Caenorhabditis_elegans
ENSG00000136628	EPRS	100	96.693	ENSCJAG00000003967	EPRS	100	96.693	Callithrix_jacchus
ENSG00000136628	EPRS	100	93.254	ENSCAFG00000010873	EPRS	100	93.188	Canis_familiaris
ENSG00000136628	EPRS	100	93.320	ENSCAFG00020004097	EPRS	100	93.254	Canis_lupus_dingo
ENSG00000136628	EPRS	100	92.857	ENSCHIG00000021232	EPRS	100	92.857	Capra_hircus
ENSG00000136628	EPRS	100	93.717	ENSTSYG00000007633	EPRS	100	93.717	Carlito_syrichta
ENSG00000136628	EPRS	99	85.160	ENSCAPG00000005713	EPRS	99	85.160	Cavia_aperea
ENSG00000136628	EPRS	100	86.376	ENSCPOG00000003586	EPRS	100	86.376	Cavia_porcellus
ENSG00000136628	EPRS	100	93.585	ENSCCAG00000028256	EPRS	100	93.585	Cebus_capucinus
ENSG00000136628	EPRS	97	97.189	ENSCATG00000045050	EPRS	100	97.189	Cercocebus_atys
ENSG00000136628	EPRS	100	87.384	ENSCLAG00000003851	EPRS	100	87.318	Chinchilla_lanigera
ENSG00000136628	EPRS	100	97.934	ENSCSAG00000015776	EPRS	100	97.564	Chlorocebus_sabaeus
ENSG00000136628	EPRS	90	100.000	ENSCHOG00000000140	EPRS	99	85.795	Choloepus_hoffmanni
ENSG00000136628	EPRS	99	82.098	ENSCPBG00000001138	EPRS	99	88.155	Chrysemys_picta_bellii
ENSG00000136628	EPRS	96	58.918	ENSCING00000007544	-	94	65.000	Ciona_intestinalis
ENSG00000136628	EPRS	99	55.959	ENSCSAVG00000007760	-	100	66.441	Ciona_savignyi
ENSG00000136628	EPRS	100	98.082	ENSCANG00000022575	EPRS	100	98.082	Colobus_angolensis_palliatus
ENSG00000136628	EPRS	100	89.550	ENSCGRG00001009885	EPRS	100	89.550	Cricetulus_griseus_chok1gshd
ENSG00000136628	EPRS	99	89.706	ENSCGRG00000010134	Eprs	100	89.706	Cricetulus_griseus_crigri
ENSG00000136628	EPRS	99	70.476	ENSCSEG00000010266	eprs	99	70.356	Cynoglossus_semilaevis
ENSG00000136628	EPRS	99	72.244	ENSCVAG00000005265	eprs	100	70.759	Cyprinodon_variegatus
ENSG00000136628	EPRS	99	70.314	ENSDARG00000060494	eprs	99	70.138	Danio_rerio
ENSG00000136628	EPRS	100	92.069	ENSDNOG00000004016	EPRS	100	92.069	Dasypus_novemcinctus
ENSG00000136628	EPRS	93	90.894	ENSDORG00000004335	Eprs	98	97.546	Dipodomys_ordii
ENSG00000136628	EPRS	99	56.209	FBgn0005674	GluProRS	99	56.078	Drosophila_melanogaster
ENSG00000136628	EPRS	96	84.571	ENSETEG00000019858	EPRS	93	84.571	Echinops_telfairi
ENSG00000136628	EPRS	100	93.452	ENSEASG00005003530	EPRS	100	93.452	Equus_asinus_asinus
ENSG00000136628	EPRS	100	93.386	ENSECAG00000000700	EPRS	100	93.386	Equus_caballus
ENSG00000136628	EPRS	86	93.361	ENSEEUG00000001019	EPRS	87	93.361	Erinaceus_europaeus
ENSG00000136628	EPRS	99	71.287	ENSELUG00000019744	eprs	99	71.231	Esox_lucius
ENSG00000136628	EPRS	100	93.320	ENSFCAG00000002590	EPRS	100	93.320	Felis_catus
ENSG00000136628	EPRS	100	79.742	ENSFALG00000012160	EPRS	100	79.097	Ficedula_albicollis
ENSG00000136628	EPRS	99	86.564	ENSFDAG00000021307	EPRS	100	86.631	Fukomys_damarensis
ENSG00000136628	EPRS	99	72.346	ENSFHEG00000001390	eprs	100	69.940	Fundulus_heteroclitus
ENSG00000136628	EPRS	83	80.913	ENSGMOG00000009984	eprs	92	80.913	Gadus_morhua
ENSG00000136628	EPRS	100	79.341	ENSGALG00000009598	EPRS	100	78.961	Gallus_gallus
ENSG00000136628	EPRS	99	68.334	ENSGAFG00000000716	eprs	99	68.483	Gambusia_affinis
ENSG00000136628	EPRS	100	66.563	ENSGACG00000014823	eprs	100	67.584	Gasterosteus_aculeatus
ENSG00000136628	EPRS	86	56.886	ENSGACG00000001445	-	100	65.411	Gasterosteus_aculeatus
ENSG00000136628	EPRS	97	82.641	ENSGAGG00000017949	EPRS	99	82.301	Gopherus_agassizii
ENSG00000136628	EPRS	100	99.206	ENSGGOG00000012404	EPRS	100	99.206	Gorilla_gorilla
ENSG00000136628	EPRS	99	72.142	ENSHBUG00000019547	eprs	99	69.494	Haplochromis_burtoni
ENSG00000136628	EPRS	100	86.243	ENSHGLG00000001974	EPRS	100	86.310	Heterocephalus_glaber_female
ENSG00000136628	EPRS	100	86.111	ENSHGLG00100003853	EPRS	100	86.177	Heterocephalus_glaber_male
ENSG00000136628	EPRS	97	70.129	ENSHCOG00000001640	eprs	99	74.652	Hippocampus_comes
ENSG00000136628	EPRS	99	72.328	ENSIPUG00000023784	eprs	99	71.832	Ictalurus_punctatus
ENSG00000136628	EPRS	100	91.667	ENSSTOG00000011870	EPRS	98	91.284	Ictidomys_tridecemlineatus
ENSG00000136628	EPRS	100	88.169	ENSJJAG00000022291	Eprs	100	88.169	Jaculus_jaculus
ENSG00000136628	EPRS	99	71.711	ENSKMAG00000001181	eprs	99	71.213	Kryptolebias_marmoratus
ENSG00000136628	EPRS	98	71.525	ENSLBEG00000016168	eprs	100	71.285	Labrus_bergylta
ENSG00000136628	EPRS	95	86.454	ENSLACG00000011773	EPRS	99	77.428	Latimeria_chalumnae
ENSG00000136628	EPRS	100	90.675	ENSLAFG00000004981	EPRS	100	90.675	Loxodonta_africana
ENSG00000136628	EPRS	100	98.082	ENSMFAG00000041902	EPRS	100	98.082	Macaca_fascicularis
ENSG00000136628	EPRS	100	98.148	ENSMMUG00000008722	EPRS	100	98.148	Macaca_mulatta
ENSG00000136628	EPRS	100	98.148	ENSMNEG00000023887	EPRS	100	98.148	Macaca_nemestrina
ENSG00000136628	EPRS	100	94.254	ENSMLEG00000032585	EPRS	100	94.254	Mandrillus_leucophaeus
ENSG00000136628	EPRS	99	72.251	ENSMAMG00000006099	eprs	100	71.021	Mastacembelus_armatus
ENSG00000136628	EPRS	99	68.451	ENSMZEG00005004950	eprs	99	68.679	Maylandia_zebra
ENSG00000136628	EPRS	100	76.952	ENSMGAG00000009215	EPRS	100	76.939	Meleagris_gallopavo
ENSG00000136628	EPRS	100	88.757	ENSMAUG00000012512	Eprs	100	88.757	Mesocricetus_auratus
ENSG00000136628	EPRS	100	94.122	ENSMICG00000038220	EPRS	100	94.188	Microcebus_murinus
ENSG00000136628	EPRS	100	88.690	ENSMOCG00000012748	Eprs	100	88.690	Microtus_ochrogaster
ENSG00000136628	EPRS	99	69.795	ENSMMOG00000015737	eprs	99	69.216	Mola_mola
ENSG00000136628	EPRS	100	83.398	ENSMODG00000004398	EPRS	100	83.398	Monodelphis_domestica
ENSG00000136628	EPRS	99	71.030	ENSMALG00000014670	eprs	99	70.429	Monopterus_albus
ENSG00000136628	EPRS	100	89.550	MGP_CAROLIEiJ_G0015023	Eprs	100	89.550	Mus_caroli
ENSG00000136628	EPRS	100	89.418	ENSMUSG00000026615	Eprs	100	89.418	Mus_musculus
ENSG00000136628	EPRS	100	89.616	MGP_PahariEiJ_G0028255	Eprs	100	89.616	Mus_pahari
ENSG00000136628	EPRS	100	89.484	MGP_SPRETEiJ_G0015823	Eprs	100	89.484	Mus_spretus
ENSG00000136628	EPRS	100	92.857	ENSMPUG00000004156	EPRS	100	92.923	Mustela_putorius_furo
ENSG00000136628	EPRS	90	88.571	ENSMLUG00000027177	-	100	92.986	Myotis_lucifugus
ENSG00000136628	EPRS	100	88.177	ENSMLUG00000007253	-	100	88.111	Myotis_lucifugus
ENSG00000136628	EPRS	100	90.152	ENSNGAG00000009088	Eprs	100	89.954	Nannospalax_galili
ENSG00000136628	EPRS	99	69.580	ENSNBRG00000006007	eprs	99	69.282	Neolamprologus_brichardi
ENSG00000136628	EPRS	100	98.876	ENSNLEG00000013988	EPRS	100	98.876	Nomascus_leucogenys
ENSG00000136628	EPRS	82	77.358	ENSMEUG00000003870	EPRS	87	77.358	Notamacropus_eugenii
ENSG00000136628	EPRS	89	92.908	ENSOPRG00000001503	EPRS	81	92.908	Ochotona_princeps
ENSG00000136628	EPRS	99	85.762	ENSODEG00000014961	EPRS	99	85.762	Octodon_degus
ENSG00000136628	EPRS	99	73.587	ENSONIG00000003054	eprs	99	72.262	Oreochromis_niloticus
ENSG00000136628	EPRS	97	69.075	ENSOANG00000001424	-	100	69.142	Ornithorhynchus_anatinus
ENSG00000136628	EPRS	80	81.410	ENSOANG00000008558	-	100	90.021	Ornithorhynchus_anatinus
ENSG00000136628	EPRS	100	89.028	ENSOCUG00000012039	EPRS	100	89.028	Oryctolagus_cuniculus
ENSG00000136628	EPRS	99	73.047	ENSORLG00000014819	eprs	99	70.557	Oryzias_latipes
ENSG00000136628	EPRS	99	73.464	ENSORLG00020018395	eprs	99	71.374	Oryzias_latipes_hni
ENSG00000136628	EPRS	99	72.977	ENSORLG00015015996	eprs	99	70.419	Oryzias_latipes_hsok
ENSG00000136628	EPRS	97	72.399	ENSOMEG00000018971	eprs	100	74.540	Oryzias_melastigma
ENSG00000136628	EPRS	97	94.150	ENSOGAG00000005285	EPRS	100	94.150	Otolemur_garnettii
ENSG00000136628	EPRS	100	92.923	ENSOARG00000011829	EPRS	100	92.923	Ovis_aries
ENSG00000136628	EPRS	100	99.537	ENSPPAG00000036757	EPRS	100	99.537	Pan_paniscus
ENSG00000136628	EPRS	100	92.857	ENSPPRG00000012626	EPRS	100	92.857	Panthera_pardus
ENSG00000136628	EPRS	99	92.056	ENSPTIG00000012991	EPRS	99	92.056	Panthera_tigris_altaica
ENSG00000136628	EPRS	100	99.603	ENSPTRG00000001995	EPRS	100	99.603	Pan_troglodytes
ENSG00000136628	EPRS	99	97.877	ENSPANG00000004476	EPRS	99	98.284	Papio_anubis
ENSG00000136628	EPRS	99	71.049	ENSPKIG00000023015	eprs	100	68.801	Paramormyrops_kingsleyae
ENSG00000136628	EPRS	99	80.983	ENSPSIG00000010709	EPRS	100	78.914	Pelodiscus_sinensis
ENSG00000136628	EPRS	99	70.200	ENSPMGG00000023169	eprs	99	69.828	Periophthalmus_magnuspinnatus
ENSG00000136628	EPRS	100	86.883	ENSPEMG00000017287	Eprs	100	83.828	Peromyscus_maniculatus_bairdii
ENSG00000136628	EPRS	100	84.676	ENSPCIG00000009736	EPRS	100	84.676	Phascolarctos_cinereus
ENSG00000136628	EPRS	99	70.328	ENSPFOG00000017972	eprs	99	69.221	Poecilia_formosa
ENSG00000136628	EPRS	99	68.845	ENSPLAG00000016198	EPRS	99	69.800	Poecilia_latipinna
ENSG00000136628	EPRS	65	72.324	ENSPMEG00000022964	eprs	100	69.724	Poecilia_mexicana
ENSG00000136628	EPRS	99	69.034	ENSPMEG00000001890	EPRS	99	70.023	Poecilia_mexicana
ENSG00000136628	EPRS	99	71.476	ENSPREG00000004302	eprs	100	71.485	Poecilia_reticulata
ENSG00000136628	EPRS	100	97.140	ENSPPYG00000000210	EPRS	100	97.140	Pongo_abelii
ENSG00000136628	EPRS	89	90.190	ENSPCAG00000015737	EPRS	93	90.190	Procavia_capensis
ENSG00000136628	EPRS	100	84.256	ENSPCOG00000004103	EPRS	98	92.342	Propithecus_coquereli
ENSG00000136628	EPRS	100	88.426	ENSPVAG00000013147	EPRS	100	88.426	Pteropus_vampyrus
ENSG00000136628	EPRS	99	72.405	ENSPNYG00000007931	eprs	99	69.697	Pundamilia_nyererei
ENSG00000136628	EPRS	99	71.151	ENSPNAG00000003344	eprs	99	69.571	Pygocentrus_nattereri
ENSG00000136628	EPRS	100	88.029	ENSRNOG00000002393	Eprs	100	88.029	Rattus_norvegicus
ENSG00000136628	EPRS	93	98.428	ENSRBIG00000034767	EPRS	100	98.428	Rhinopithecus_bieti
ENSG00000136628	EPRS	100	98.148	ENSRROG00000039885	EPRS	100	98.148	Rhinopithecus_roxellana
ENSG00000136628	EPRS	66	45.107	YGL245W	GUS1	89	45.750	Saccharomyces_cerevisiae
ENSG00000136628	EPRS	100	97.354	ENSSBOG00000029926	EPRS	100	97.354	Saimiri_boliviensis_boliviensis
ENSG00000136628	EPRS	99	82.712	ENSSHAG00000002391	EPRS	99	85.756	Sarcophilus_harrisii
ENSG00000136628	EPRS	99	70.663	ENSSFOG00015007233	eprs	99	69.532	Scleropages_formosus
ENSG00000136628	EPRS	99	71.513	ENSSMAG00000011150	eprs	99	71.140	Scophthalmus_maximus
ENSG00000136628	EPRS	99	71.873	ENSSDUG00000008910	eprs	99	71.749	Seriola_dumerili
ENSG00000136628	EPRS	99	73.394	ENSSLDG00000015153	eprs	99	73.669	Seriola_lalandi_dorsalis
ENSG00000136628	EPRS	99	84.041	ENSSARG00000012244	EPRS	100	83.842	Sorex_araneus
ENSG00000136628	EPRS	99	74.838	ENSSPUG00000009384	EPRS	97	74.974	Sphenodon_punctatus
ENSG00000136628	EPRS	99	73.132	ENSSPAG00000010408	eprs	99	71.122	Stegastes_partitus
ENSG00000136628	EPRS	100	91.931	ENSSSCG00000010821	EPRS	100	91.931	Sus_scrofa
ENSG00000136628	EPRS	99	81.654	ENSTGUG00000002796	EPRS	100	81.588	Taeniopygia_guttata
ENSG00000136628	EPRS	99	71.222	ENSTRUG00000006901	eprs	99	70.792	Takifugu_rubripes
ENSG00000136628	EPRS	99	66.053	ENSTNIG00000011902	eprs	99	66.258	Tetraodon_nigroviridis
ENSG00000136628	EPRS	100	92.725	ENSTBEG00000008365	EPRS	100	92.725	Tupaia_belangeri
ENSG00000136628	EPRS	100	92.659	ENSTTRG00000013013	EPRS	100	92.659	Tursiops_truncatus
ENSG00000136628	EPRS	100	93.122	ENSUAMG00000020817	EPRS	100	93.188	Ursus_americanus
ENSG00000136628	EPRS	97	92.427	ENSUMAG00000020899	EPRS	100	93.551	Ursus_maritimus
ENSG00000136628	EPRS	99	84.265	ENSVPAG00000008903	EPRS	100	80.622	Vicugna_pacos
ENSG00000136628	EPRS	100	93.320	ENSVVUG00000012841	EPRS	77	93.254	Vulpes_vulpes
ENSG00000136628	EPRS	99	75.742	ENSXETG00000002724	eprs	99	75.676	Xenopus_tropicalis
ENSG00000136628	EPRS	91	72.991	ENSXCOG00000018038	eprs	99	72.869	Xiphophorus_couchianus
ENSG00000136628	EPRS	99	71.558	ENSXMAG00000011690	eprs	99	71.151	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004818	glutamate-tRNA ligase activity	-	TAS	Function
GO:0004827	proline-tRNA ligase activity	21873635.	IBA	Function
GO:0004827	proline-tRNA ligase activity	24100331.	IDA	Function
GO:0004827	proline-tRNA ligase activity	-	TAS	Function
GO:0005515	protein binding	9556618.10913161.11142386.21220307.22386318.24100331.24312579.24606901.28178239.28380382.30021884.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	10791971.	IDA	Component
GO:0005829	cytosol	19289464.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	ISS	Component
GO:0006418	tRNA aminoacylation for protein translation	-	TAS	Process
GO:0006424	glutamyl-tRNA aminoacylation	-	IEA	Process
GO:0006433	prolyl-tRNA aminoacylation	21873635.	IBA	Process
GO:0006433	prolyl-tRNA aminoacylation	24100331.	IDA	Process
GO:0008270	zinc ion binding	24100331.	IDA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	21873635.	IBA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	10791971.19131329.	IDA	Component
GO:0017148	negative regulation of translation	23071094.	IDA	Process
GO:0017148	negative regulation of translation	15479637.	IMP	Process
GO:0032869	cellular response to insulin stimulus	-	ISS	Process
GO:0035613	RNA stem-loop binding	15479637.	IDA	Function
GO:0042802	identical protein binding	23263184.	IPI	Function
GO:0042803	protein homodimerization activity	24100331.	IPI	Function
GO:0044539	long-chain fatty acid import	28178239.	IMP	Process
GO:0051020	GTPase binding	24337748.	IPI	Function
GO:0065003	protein-containing complex assembly	8188258.	TAS	Process
GO:0071346	cellular response to interferon-gamma	15479637.	IDA	Process
GO:0097452	GAIT complex	15479637.23071094.	IDA	Component
GO:1990904	ribonucleoprotein complex	15479637.	IDA	Component