EuRBPDB

Description

Ensembl ID: ENSG00000136811 (Gene tree)
Gene ID: 4957
Gene Symbol: ODF2
Alias: ODF84|CT134
Full Name: outer dense fiber of sperm tails 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 46,138 bases
Position: chr9:128,455,155-128,501,292
Accession: 8114
RBP type: non-canonical RBP
Summary: The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers. [provided by RefSeq, Oct 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000469582	ODF2-214	1054	-	-	- (aa)	-	-
ENST00000497812	ODF2-218	578	-	ENSP00000474949	144 (aa)	-	S4R411
ENST00000483070	ODF2-216	723	-	ENSP00000474651	241 (aa)	-	S4R3R9
ENST00000444119	ODF2-210	2418	XM_011518732	ENSP00000394506	805 (aa)	XP_011517034	Q5BJF6
ENST00000372807	ODF2-203	2475	-	ENSP00000361893	824 (aa)	-	Q5BJF6
ENST00000421776	ODF2-207	1254	-	ENSP00000395489	386 (aa)	-	Q5T4C3
ENST00000372814	ODF2-204	2249	-	ENSP00000361901	701 (aa)	-	Q5BJF6
ENST00000446274	ODF2-212	822	-	ENSP00000415290	156 (aa)	-	Q5T4C8
ENST00000604420	ODF2-220	3030	XM_005252011	ENSP00000473949	829 (aa)	XP_005252068	Q5BJF6
ENST00000470061	ODF2-215	588	-	ENSP00000475118	100 (aa)	-	S4R462
ENST00000351030	ODF2-201	3899	XM_011518728	ENSP00000342581	824 (aa)	XP_011517030	Q5BJF6
ENST00000444993	ODF2-211	1007	-	-	- (aa)	-	-
ENST00000546203	ODF2-219	2140	-	ENSP00000437579	638 (aa)	-	Q5BJF6
ENST00000393533	ODF2-206	2086	-	ENSP00000377166	657 (aa)	-	Q5BJF6
ENST00000372791	ODF2-202	2375	-	ENSP00000361877	638 (aa)	-	Q5BJF6
ENST00000488909	ODF2-217	1525	-	-	- (aa)	-	-
ENST00000434106	ODF2-209	3890	XM_005252012	ENSP00000403453	829 (aa)	XP_005252069	Q5BJF6
ENST00000448249	ODF2-213	2059	-	ENSP00000396687	576 (aa)	-	Q5BJF6
ENST00000393527	ODF2-205	3653	XM_011518723	ENSP00000377161	805 (aa)	XP_011517025	Q5BJF6
ENST00000432065	ODF2-208	934	-	ENSP00000407852	205 (aa)	-	Q5T4C6

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136811	ODF2	100	99.359	ENSMUSG00000026790	Odf2	100	99.275	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000086	G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0000922	spindle pole	-	IEA	Component
GO:0001520	outer dense fiber	-	IEA	Component
GO:0005198	structural molecule activity	10072582.	TAS	Function
GO:0005515	protein binding	16980960.23355646.28422092.	IPI	Function
GO:0005634	nucleus	21630459.	HDA	Component
GO:0005813	centrosome	21399614.24157919.	IDA	Component
GO:0005814	centriole	24421332.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005874	microtubule	-	IEA	Component
GO:0007275	multicellular organism development	-	IEA	Process
GO:0007286	spermatid development	-	IEA	Process
GO:0008104	protein localization	23213374.28422092.	IMP	Process
GO:0010389	regulation of G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0010457	centriole-centriole cohesion	23213374.	IGI	Process
GO:0036126	sperm flagellum	-	ISS	Component
GO:0044782	cilium organization	23400999.	IGI	Process
GO:0097539	ciliary transition fiber	-	IEA	Component
GO:0097711	ciliary basal body-plasma membrane docking	-	TAS	Process
GO:0120103	centriolar subdistal appendage	23213374.	IDA	Component