EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000136897 (Gene tree)
Gene ID: 54534
Gene Symbol: MRPL50
Alias: FLJ20493|MRP-L50
Full Name: mitochondrial ribosomal protein L50
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 11,009 bases
Position: chr9:101,387,633-101,398,641
Accession: 16654
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000363999	Ribosomal_L50	PF10501.9	2e-11	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374865	MRPL50-201	3332	-	ENSP00000363999	158 (aa)	-	Q8N5N7

Gene Model

Click here to download ENSG00000136897's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000136897's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136897	MRPL50	100	78.616	ENSAMEG00000000650	MRPL50	100	75.472	Ailuropoda_melanoleuca
ENSG00000136897	MRPL50	76	58.333	ENSAPLG00000000732	MRPL50	81	60.550	Anas_platyrhynchos
ENSG00000136897	MRPL50	88	54.861	ENSACAG00000017435	MRPL50	69	62.162	Anolis_carolinensis
ENSG00000136897	MRPL50	100	87.421	ENSANAG00000016867	-	100	83.648	Aotus_nancymaae
ENSG00000136897	MRPL50	100	88.050	ENSANAG00000000786	-	100	84.277	Aotus_nancymaae
ENSG00000136897	MRPL50	100	76.730	ENSBTAG00000008962	MRPL50	100	72.956	Bos_taurus
ENSG00000136897	MRPL50	100	86.792	ENSCJAG00000048689	MRPL50	100	83.019	Callithrix_jacchus
ENSG00000136897	MRPL50	100	78.616	ENSCAFG00000032597	MRPL50	100	75.472	Canis_familiaris
ENSG00000136897	MRPL50	100	79.245	ENSCAFG00020019468	MRPL50	100	76.101	Canis_lupus_dingo
ENSG00000136897	MRPL50	100	76.730	ENSCHIG00000015308	MRPL50	100	73.585	Capra_hircus
ENSG00000136897	MRPL50	100	82.390	ENSTSYG00000034810	MRPL50	100	78.616	Carlito_syrichta
ENSG00000136897	MRPL50	81	82.031	ENSCAPG00000003170	MRPL50	87	82.883	Cavia_aperea
ENSG00000136897	MRPL50	100	76.582	ENSCPOG00000034033	MRPL50	100	76.582	Cavia_porcellus
ENSG00000136897	MRPL50	100	86.792	ENSCCAG00000033569	MRPL50	100	83.019	Cebus_capucinus
ENSG00000136897	MRPL50	100	96.203	ENSCATG00000039456	MRPL50	100	96.203	Cercocebus_atys
ENSG00000136897	MRPL50	100	77.215	ENSCLAG00000010221	MRPL50	100	77.215	Chinchilla_lanigera
ENSG00000136897	MRPL50	100	96.203	ENSCSAG00000011188	MRPL50	100	96.203	Chlorocebus_sabaeus
ENSG00000136897	MRPL50	59	80.851	ENSCHOG00000010657	-	100	80.851	Choloepus_hoffmanni
ENSG00000136897	MRPL50	96	56.863	ENSCPBG00000009521	MRPL50	97	52.288	Chrysemys_picta_bellii
ENSG00000136897	MRPL50	100	94.937	ENSCANG00000029997	MRPL50	100	94.937	Colobus_angolensis_palliatus
ENSG00000136897	MRPL50	100	75.472	ENSCGRG00001023970	Mrpl50	100	72.956	Cricetulus_griseus_chok1gshd
ENSG00000136897	MRPL50	100	75.472	ENSCGRG00000003977	Mrpl50	100	72.956	Cricetulus_griseus_crigri
ENSG00000136897	MRPL50	100	75.309	ENSDNOG00000035230	MRPL50	100	75.309	Dasypus_novemcinctus
ENSG00000136897	MRPL50	100	72.956	ENSDORG00000012829	Mrpl50	100	71.698	Dipodomys_ordii
ENSG00000136897	MRPL50	100	71.069	ENSETEG00000001589	MRPL50	98	68.553	Echinops_telfairi
ENSG00000136897	MRPL50	100	83.648	ENSEASG00005022900	MRPL50	100	82.278	Equus_asinus_asinus
ENSG00000136897	MRPL50	95	72.848	ENSEEUG00000014898	MRPL50	100	70.000	Erinaceus_europaeus
ENSG00000136897	MRPL50	100	79.245	ENSFCAG00000030003	MRPL50	100	76.101	Felis_catus
ENSG00000136897	MRPL50	80	56.154	ENSFALG00000000234	MRPL50	99	59.633	Ficedula_albicollis
ENSG00000136897	MRPL50	100	76.582	ENSFDAG00000008769	MRPL50	76	76.582	Fukomys_damarensis
ENSG00000136897	MRPL50	72	62.281	ENSGALG00000015543	MRPL50	98	50.943	Gallus_gallus
ENSG00000136897	MRPL50	96	56.863	ENSGAGG00000012487	MRPL50	97	52.288	Gopherus_agassizii
ENSG00000136897	MRPL50	100	96.250	ENSGGOG00000009431	MRPL50	100	96.250	Gorilla_gorilla
ENSG00000136897	MRPL50	100	75.316	ENSGGOG00000036374	-	94	75.316	Gorilla_gorilla
ENSG00000136897	MRPL50	100	77.215	ENSHGLG00000004483	MRPL50	100	77.215	Heterocephalus_glaber_female
ENSG00000136897	MRPL50	100	77.215	ENSHGLG00100001750	MRPL50	100	77.215	Heterocephalus_glaber_male
ENSG00000136897	MRPL50	100	81.761	ENSSTOG00000026770	MRPL50	100	78.616	Ictidomys_tridecemlineatus
ENSG00000136897	MRPL50	100	72.956	ENSJJAG00000015402	Mrpl50	100	72.327	Jaculus_jaculus
ENSG00000136897	MRPL50	84	56.391	ENSLACG00000003598	MRPL50	79	54.135	Latimeria_chalumnae
ENSG00000136897	MRPL50	100	77.987	ENSLAFG00000031753	MRPL50	100	74.843	Loxodonta_africana
ENSG00000136897	MRPL50	100	95.570	ENSMFAG00000000380	MRPL50	100	95.570	Macaca_fascicularis
ENSG00000136897	MRPL50	100	96.203	ENSMNEG00000039950	MRPL50	100	96.203	Macaca_nemestrina
ENSG00000136897	MRPL50	100	96.203	ENSMLEG00000037472	MRPL50	100	96.203	Mandrillus_leucophaeus
ENSG00000136897	MRPL50	83	60.150	ENSMGAG00000016023	MRPL50	80	63.636	Meleagris_gallopavo
ENSG00000136897	MRPL50	100	72.956	ENSMAUG00000002882	Mrpl50	100	70.440	Mesocricetus_auratus
ENSG00000136897	MRPL50	100	84.906	ENSMICG00000045766	-	100	81.132	Microcebus_murinus
ENSG00000136897	MRPL50	100	86.792	ENSMICG00000049266	-	100	83.019	Microcebus_murinus
ENSG00000136897	MRPL50	100	87.421	ENSMICG00000045179	-	100	83.648	Microcebus_murinus
ENSG00000136897	MRPL50	100	72.500	ENSMOCG00000016919	Mrpl50	100	69.375	Microtus_ochrogaster
ENSG00000136897	MRPL50	87	62.143	ENSMODG00000022960	MRPL50	97	62.500	Monodelphis_domestica
ENSG00000136897	MRPL50	100	77.987	MGP_CAROLIEiJ_G0026011	Mrpl50	100	74.214	Mus_caroli
ENSG00000136897	MRPL50	100	77.358	ENSMUSG00000044018	Mrpl50	100	73.585	Mus_musculus
ENSG00000136897	MRPL50	100	77.987	MGP_PahariEiJ_G0028347	Mrpl50	100	74.214	Mus_pahari
ENSG00000136897	MRPL50	100	76.101	MGP_SPRETEiJ_G0026974	Mrpl50	100	72.327	Mus_spretus
ENSG00000136897	MRPL50	100	79.874	ENSMPUG00000006899	MRPL50	100	76.101	Mustela_putorius_furo
ENSG00000136897	MRPL50	100	71.698	ENSMLUG00000006011	MRPL50	100	68.553	Myotis_lucifugus
ENSG00000136897	MRPL50	100	76.101	ENSNGAG00000021876	Mrpl50	100	72.956	Nannospalax_galili
ENSG00000136897	MRPL50	100	71.698	ENSNLEG00000032422	-	100	68.553	Nomascus_leucogenys
ENSG00000136897	MRPL50	100	96.203	ENSNLEG00000017112	MRPL50	100	96.203	Nomascus_leucogenys
ENSG00000136897	MRPL50	81	59.375	ENSMEUG00000005656	-	86	63.063	Notamacropus_eugenii
ENSG00000136897	MRPL50	100	73.125	ENSOPRG00000015557	-	100	70.000	Ochotona_princeps
ENSG00000136897	MRPL50	100	74.051	ENSODEG00000005275	MRPL50	100	74.051	Octodon_degus
ENSG00000136897	MRPL50	100	60.377	ENSOANG00000004770	MRPL50	100	59.119	Ornithorhynchus_anatinus
ENSG00000136897	MRPL50	100	71.605	ENSOCUG00000006340	MRPL50	100	67.284	Oryctolagus_cuniculus
ENSG00000136897	MRPL50	100	84.277	ENSOGAG00000025381	MRPL50	100	80.503	Otolemur_garnettii
ENSG00000136897	MRPL50	100	76.101	ENSOARG00000007538	MRPL50	100	72.956	Ovis_aries
ENSG00000136897	MRPL50	100	97.468	ENSPPAG00000027646	MRPL50	100	97.468	Pan_paniscus
ENSG00000136897	MRPL50	95	72.848	ENSPPAG00000035776	-	98	69.536	Pan_paniscus
ENSG00000136897	MRPL50	100	78.616	ENSPPRG00000002099	MRPL50	100	77.987	Panthera_pardus
ENSG00000136897	MRPL50	100	79.245	ENSPTIG00000014107	MRPL50	100	76.101	Panthera_tigris_altaica
ENSG00000136897	MRPL50	95	72.848	ENSPTRG00000043662	-	98	69.536	Pan_troglodytes
ENSG00000136897	MRPL50	100	98.101	ENSPTRG00000050419	MRPL50	100	98.101	Pan_troglodytes
ENSG00000136897	MRPL50	100	96.203	ENSPANG00000011880	-	100	96.203	Papio_anubis
ENSG00000136897	MRPL50	100	96.203	ENSPANG00000025676	-	100	96.203	Papio_anubis
ENSG00000136897	MRPL50	81	65.116	ENSPSIG00000000308	MRPL50	85	64.865	Pelodiscus_sinensis
ENSG00000136897	MRPL50	100	98.101	ENSPPYG00000019451	MRPL50	100	98.101	Pongo_abelii
ENSG00000136897	MRPL50	80	75.781	ENSPCAG00000006809	MRPL50	87	76.577	Procavia_capensis
ENSG00000136897	MRPL50	96	77.632	ENSPVAG00000000934	MRPL50	100	74.342	Pteropus_vampyrus
ENSG00000136897	MRPL50	100	76.101	ENSRNOG00000053615	Mrpl50	100	72.956	Rattus_norvegicus
ENSG00000136897	MRPL50	100	94.937	ENSRBIG00000037387	MRPL50	100	94.937	Rhinopithecus_bieti
ENSG00000136897	MRPL50	100	94.937	ENSRROG00000036343	-	100	97.656	Rhinopithecus_roxellana
ENSG00000136897	MRPL50	100	94.937	ENSRROG00000037165	-	100	94.937	Rhinopithecus_roxellana
ENSG00000136897	MRPL50	100	87.421	ENSSBOG00000022031	MRPL50	100	83.648	Saimiri_boliviensis_boliviensis
ENSG00000136897	MRPL50	81	61.538	ENSSHAG00000012132	-	69	61.261	Sarcophilus_harrisii
ENSG00000136897	MRPL50	100	72.956	ENSSARG00000013111	MRPL50	100	69.811	Sorex_araneus
ENSG00000136897	MRPL50	84	60.448	ENSSPUG00000008348	MRPL50	85	57.895	Sphenodon_punctatus
ENSG00000136897	MRPL50	100	79.874	ENSSSCG00000027974	-	100	76.101	Sus_scrofa
ENSG00000136897	MRPL50	100	55.346	ENSSSCG00000035063	-	100	51.899	Sus_scrofa
ENSG00000136897	MRPL50	70	54.054	ENSTGUG00000015005	-	82	54.206	Taeniopygia_guttata
ENSG00000136897	MRPL50	84	52.899	ENSTGUG00000000649	-	79	56.364	Taeniopygia_guttata
ENSG00000136897	MRPL50	72	55.752	ENSTGUG00000015014	-	81	55.455	Taeniopygia_guttata
ENSG00000136897	MRPL50	70	56.757	ENSTGUG00000014990	-	82	57.009	Taeniopygia_guttata
ENSG00000136897	MRPL50	80	83.465	ENSTBEG00000004543	-	87	81.982	Tupaia_belangeri
ENSG00000136897	MRPL50	80	83.465	ENSTBEG00000009729	-	87	81.982	Tupaia_belangeri
ENSG00000136897	MRPL50	80	85.938	ENSTTRG00000014349	MRPL50	87	86.486	Tursiops_truncatus
ENSG00000136897	MRPL50	100	79.874	ENSUAMG00000020927	MRPL50	100	76.101	Ursus_americanus
ENSG00000136897	MRPL50	100	79.874	ENSUMAG00000012974	MRPL50	100	76.101	Ursus_maritimus
ENSG00000136897	MRPL50	100	79.245	ENSVPAG00000002242	MRPL50	100	75.472	Vicugna_pacos
ENSG00000136897	MRPL50	100	77.987	ENSVVUG00000019255	MRPL50	100	74.843	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005762	mitochondrial large ribosomal subunit	25278503.28892042.	IDA	Component
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process