EuRBPDB

Description

Ensembl ID: ENSG00000136938 (Gene tree)
Gene ID: 10541
Gene Symbol: ANP32B
Alias: SSP29|PHAPI2|APRIL
Full Name: acidic nuclear phosphoprotein 32 family member B
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 32,737 bases
Position: chr9:97,983,207-98,015,943
Accession: 16677
RBP type: non-canonical RBP
Summary: (Acidic Nuclear Phosphoprotein 32 Family Member B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include histone binding and RNA polymerase binding. An important paralog of this gene is ANP32A.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000473205	ANP32B-202	687	-	-	- (aa)	-	-
ENST00000339399	ANP32B-201	1463	-	ENSP00000345848	251 (aa)	-	Q92688
ENST00000486769	ANP32B-203	400	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000136938	Platelet Count	6.147e-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000136938	rs11338569	9	98001175	C	Mean corpuscular hemoglobin	27863252	[0.024-0.04] unit decrease	0.03195319	EFO_0004527
ENSG00000136938	rs11338569	9	98001175	C	Red blood cell count	27863252	[0.019-0.036] unit increase	0.02785787	EFO_0004305
ENSG00000136938	rs76917914	9	98009158	G	Immature fraction of reticulocytes	27863252	[0.021-0.038] unit decrease	0.0291362	EFO_0007986

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000136938	ANP32B	64	81.366	ENSG00000140350	ANP32A	90	81.250	Homo_sapiens
ENSG00000136938	ANP32B	61	66.447	ENSG00000143401	ANP32E	96	47.799	Homo_sapiens
ENSG00000136938	ANP32B	70	85.714	ENSMUSG00000028333	Anp32b	59	88.125	Mus_musculus
ENSG00000136938	ANP32B	63	65.823	ENSMUSG00000015749	Anp32e	100	68.224	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001944	vasculature development	-	IEA	Process
GO:0005515	protein binding	21988832.25416956.	IPI	Function
GO:0005634	nucleus	16791210.	HDA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	9285060.17178712.	IDA	Component
GO:0005730	nucleolus	9285060.	IDA	Component
GO:0005737	cytoplasm	17178712.	IDA	Component
GO:0006334	nucleosome assembly	20538007.	IDA	Process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	20015864.	IMP	Process
GO:0021591	ventricular system development	-	IEA	Process
GO:0042393	histone binding	21873635.	IBA	Function
GO:0042393	histone binding	20538007.	IDA	Function
GO:0045596	negative regulation of cell differentiation	22705300.	IDA	Process
GO:0046827	positive regulation of protein export from nucleus	17178712.	IMP	Process
GO:0048839	inner ear development	-	IEA	Process
GO:0060021	roof of mouth development	-	IEA	Process
GO:0070062	extracellular exosome	20458337.	HDA	Component
GO:0070063	RNA polymerase binding	9285060.	IDA	Function