EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000137054 (Gene tree)
Gene ID: 64425
Gene Symbol: POLR1E
Alias: FLJ13390|PAF53|FLJ13970|PRAF1
Full Name: RNA polymerase I subunit E
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 17,763 bases
Position: chr9:37,485,935-37,503,697
Accession: 17631
RBP type: canonical RBP
Summary: (RNA Polymerase I Subunit E) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Escape and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include DNA-directed 5'-3' RNA polymerase activity and RNA polymerase I transcription factor binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000367029	RNA_pol_I_A49	PF06870.12	2.6e-108	1	1
ENSP00000367023	RNA_pol_I_A49	PF06870.12	4.2e-108	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
14585813	Expression of nucleolar-related proteins in porcine preimplantation embryos produced in vivo and in vitro.	Biol Reprod	2004 Apr	Bjerregaard B	-
9688843	Regulation of ribosomal DNA transcription by insulin.	Am J Physiol	1998 Jul	Hannan KM	doi: 10.1152/ajpcell.1998.275.1.C130.
29591153	-	-	-	-	-
16187064	Re-localization of nuclear DNA helicase II during the growth period of bovine oocytes.	Histochem Cell Biol	2006 Jan	Baran V	-
14627545	Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.	Biol Reprod	2004 Apr	Bjerregaard B	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000377798	POLR1E-202	1868	-	ENSP00000367029	419 (aa)	-	Q9GZS1
ENST00000377792	POLR1E-201	2229	XM_005251547	ENSP00000367023	481 (aa)	XP_005251604	Q9GZS1
ENST00000442009	POLR1E-203	1805	-	ENSP00000399887	141 (aa)	-	E7EX70

Gene Model

Click here to download ENSG00000137054's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000137054's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000137054	POLR1E	98	42.754	ENSAPOG00000012452	polr1e	99	42.754	Acanthochromis_polyacanthus
ENSG00000137054	POLR1E	100	78.925	ENSAMEG00000010193	POLR1E	97	78.925	Ailuropoda_melanoleuca
ENSG00000137054	POLR1E	94	42.680	ENSACIG00000009884	polr1e	98	43.257	Amphilophus_citrinellus
ENSG00000137054	POLR1E	98	45.652	ENSAOCG00000005665	polr1e	99	45.652	Amphiprion_ocellaris
ENSG00000137054	POLR1E	98	45.411	ENSAPEG00000020581	polr1e	99	45.411	Amphiprion_percula
ENSG00000137054	POLR1E	96	45.946	ENSATEG00000020609	polr1e	97	45.946	Anabas_testudineus
ENSG00000137054	POLR1E	80	55.000	ENSAPLG00000010340	POLR1E	100	54.856	Anas_platyrhynchos
ENSG00000137054	POLR1E	100	94.272	ENSANAG00000038046	POLR1E	100	94.272	Aotus_nancymaae
ENSG00000137054	POLR1E	99	44.524	ENSACLG00000013685	polr1e	99	44.524	Astatotilapia_calliptera
ENSG00000137054	POLR1E	94	45.000	ENSAMXG00000018181	polr1e	99	43.373	Astyanax_mexicanus
ENSG00000137054	POLR1E	100	87.112	ENSBTAG00000012243	POLR1E	100	87.112	Bos_taurus
ENSG00000137054	POLR1E	94	88.579	ENSCJAG00000010512	POLR1E	93	93.048	Callithrix_jacchus
ENSG00000137054	POLR1E	100	88.067	ENSCAFG00000002377	POLR1E	100	88.067	Canis_familiaris
ENSG00000137054	POLR1E	100	87.828	ENSCAFG00020017851	POLR1E	100	87.828	Canis_lupus_dingo
ENSG00000137054	POLR1E	100	86.158	ENSCHIG00000019479	POLR1E	100	86.158	Capra_hircus
ENSG00000137054	POLR1E	100	87.589	ENSTSYG00000002075	POLR1E	100	87.589	Carlito_syrichta
ENSG00000137054	POLR1E	68	83.275	ENSCAPG00000015653	POLR1E	99	83.275	Cavia_aperea
ENSG00000137054	POLR1E	99	84.211	ENSCPOG00000009965	POLR1E	100	84.211	Cavia_porcellus
ENSG00000137054	POLR1E	100	86.396	ENSCCAG00000029460	POLR1E	100	86.396	Cebus_capucinus
ENSG00000137054	POLR1E	100	98.091	ENSCATG00000031732	POLR1E	100	98.305	Cercocebus_atys
ENSG00000137054	POLR1E	87	87.978	ENSCLAG00000012701	POLR1E	96	87.978	Chinchilla_lanigera
ENSG00000137054	POLR1E	100	97.613	ENSCSAG00000010782	POLR1E	100	97.613	Chlorocebus_sabaeus
ENSG00000137054	POLR1E	99	72.651	ENSCHOG00000013024	POLR1E	99	72.651	Choloepus_hoffmanni
ENSG00000137054	POLR1E	98	65.207	ENSCPBG00000006923	POLR1E	99	66.180	Chrysemys_picta_bellii
ENSG00000137054	POLR1E	100	97.375	ENSCANG00000036112	POLR1E	100	97.768	Colobus_angolensis_palliatus
ENSG00000137054	POLR1E	99	78.947	ENSCGRG00001006197	Polr1e	96	78.947	Cricetulus_griseus_chok1gshd
ENSG00000137054	POLR1E	99	78.469	ENSCGRG00000006430	Polr1e	96	78.469	Cricetulus_griseus_crigri
ENSG00000137054	POLR1E	97	42.092	ENSCSEG00000005121	polr1e	98	42.092	Cynoglossus_semilaevis
ENSG00000137054	POLR1E	96	42.752	ENSCVAG00000019759	polr1e	97	42.752	Cyprinodon_variegatus
ENSG00000137054	POLR1E	94	43.073	ENSDARG00000006434	polr1e	97	42.579	Danio_rerio
ENSG00000137054	POLR1E	100	77.564	ENSDNOG00000010257	POLR1E	99	77.350	Dasypus_novemcinctus
ENSG00000137054	POLR1E	89	81.600	ENSDORG00000026463	-	96	81.600	Dipodomys_ordii
ENSG00000137054	POLR1E	85	82.682	ENSETEG00000018204	POLR1E	99	82.682	Echinops_telfairi
ENSG00000137054	POLR1E	100	89.499	ENSEASG00005000675	POLR1E	100	89.499	Equus_asinus_asinus
ENSG00000137054	POLR1E	100	89.737	ENSECAG00000014669	POLR1E	100	89.737	Equus_caballus
ENSG00000137054	POLR1E	94	74.873	ENSEEUG00000011928	POLR1E	98	70.940	Erinaceus_europaeus
ENSG00000137054	POLR1E	97	45.588	ENSELUG00000008150	polr1e	97	45.588	Esox_lucius
ENSG00000137054	POLR1E	100	88.067	ENSFCAG00000013081	POLR1E	100	88.067	Felis_catus
ENSG00000137054	POLR1E	94	60.051	ENSFALG00000012950	POLR1E	99	60.152	Ficedula_albicollis
ENSG00000137054	POLR1E	99	84.450	ENSFDAG00000016917	POLR1E	100	84.450	Fukomys_damarensis
ENSG00000137054	POLR1E	98	43.341	ENSFHEG00000009801	polr1e	98	43.341	Fundulus_heteroclitus
ENSG00000137054	POLR1E	93	41.310	ENSGMOG00000003336	POLR1E	93	41.562	Gadus_morhua
ENSG00000137054	POLR1E	99	61.017	ENSGALG00000005395	POLR1E	99	61.017	Gallus_gallus
ENSG00000137054	POLR1E	97	43.137	ENSGAFG00000004850	polr1e	98	43.137	Gambusia_affinis
ENSG00000137054	POLR1E	97	43.171	ENSGACG00000016087	polr1e	98	43.171	Gasterosteus_aculeatus
ENSG00000137054	POLR1E	98	58.637	ENSGAGG00000001659	POLR1E	98	58.696	Gopherus_agassizii
ENSG00000137054	POLR1E	100	99.761	ENSGGOG00000001882	POLR1E	100	99.761	Gorilla_gorilla
ENSG00000137054	POLR1E	99	45.000	ENSHBUG00000002559	polr1e	99	45.000	Haplochromis_burtoni
ENSG00000137054	POLR1E	99	85.407	ENSHGLG00000002036	POLR1E	100	85.407	Heterocephalus_glaber_female
ENSG00000137054	POLR1E	99	85.407	ENSHGLG00100012784	POLR1E	100	85.407	Heterocephalus_glaber_male
ENSG00000137054	POLR1E	97	44.118	ENSHCOG00000002774	polr1e	98	44.363	Hippocampus_comes
ENSG00000137054	POLR1E	97	44.417	ENSIPUG00000003019	polr1e	98	44.417	Ictalurus_punctatus
ENSG00000137054	POLR1E	100	84.726	ENSSTOG00000009810	POLR1E	100	84.726	Ictidomys_tridecemlineatus
ENSG00000137054	POLR1E	99	81.295	ENSJJAG00000020731	Polr1e	96	81.295	Jaculus_jaculus
ENSG00000137054	POLR1E	95	42.750	ENSKMAG00000000046	polr1e	99	41.007	Kryptolebias_marmoratus
ENSG00000137054	POLR1E	99	45.324	ENSLBEG00000003104	polr1e	99	45.803	Labrus_bergylta
ENSG00000137054	POLR1E	85	61.219	ENSLACG00000003416	POLR1E	99	61.219	Latimeria_chalumnae
ENSG00000137054	POLR1E	99	49.762	ENSLOCG00000012859	polr1e	99	49.762	Lepisosteus_oculatus
ENSG00000137054	POLR1E	100	87.589	ENSLAFG00000012831	POLR1E	99	87.589	Loxodonta_africana
ENSG00000137054	POLR1E	100	98.329	ENSMFAG00000045465	POLR1E	100	98.305	Macaca_fascicularis
ENSG00000137054	POLR1E	100	98.329	ENSMMUG00000017892	POLR1E	100	98.329	Macaca_mulatta
ENSG00000137054	POLR1E	100	91.355	ENSMNEG00000040283	POLR1E	100	97.788	Macaca_nemestrina
ENSG00000137054	POLR1E	100	98.091	ENSMLEG00000031135	POLR1E	100	98.305	Mandrillus_leucophaeus
ENSG00000137054	POLR1E	99	43.026	ENSMAMG00000001260	polr1e	99	43.026	Mastacembelus_armatus
ENSG00000137054	POLR1E	99	44.762	ENSMZEG00005021536	polr1e	99	44.762	Maylandia_zebra
ENSG00000137054	POLR1E	100	78.759	ENSMAUG00000021044	Polr1e	97	78.759	Mesocricetus_auratus
ENSG00000137054	POLR1E	100	89.737	ENSMICG00000003673	POLR1E	100	89.737	Microcebus_murinus
ENSG00000137054	POLR1E	99	80.383	ENSMOCG00000012920	Polr1e	96	80.383	Microtus_ochrogaster
ENSG00000137054	POLR1E	93	45.316	ENSMMOG00000007391	polr1e	99	44.608	Mola_mola
ENSG00000137054	POLR1E	95	73.485	ENSMODG00000002884	POLR1E	97	73.485	Monodelphis_domestica
ENSG00000137054	POLR1E	99	43.810	ENSMALG00000002665	polr1e	99	43.810	Monopterus_albus
ENSG00000137054	POLR1E	99	76.867	MGP_CAROLIEiJ_G0025967	Polr1e	99	77.171	Mus_caroli
ENSG00000137054	POLR1E	99	77.590	ENSMUSG00000028318	Polr1e	99	77.805	Mus_musculus
ENSG00000137054	POLR1E	99	78.554	MGP_PahariEiJ_G0024114	Polr1e	99	79.104	Mus_pahari
ENSG00000137054	POLR1E	99	76.867	MGP_SPRETEiJ_G0026930	Polr1e	99	76.923	Mus_spretus
ENSG00000137054	POLR1E	100	79.531	ENSMPUG00000006040	POLR1E	99	79.318	Mustela_putorius_furo
ENSG00000137054	POLR1E	100	86.874	ENSMLUG00000012688	POLR1E	97	86.874	Myotis_lucifugus
ENSG00000137054	POLR1E	99	82.974	ENSNGAG00000002520	Polr1e	96	82.974	Nannospalax_galili
ENSG00000137054	POLR1E	99	45.000	ENSNBRG00000016822	polr1e	98	45.060	Neolamprologus_brichardi
ENSG00000137054	POLR1E	100	98.582	ENSNLEG00000003616	POLR1E	100	98.582	Nomascus_leucogenys
ENSG00000137054	POLR1E	73	76.250	ENSMEUG00000015372	-	80	76.250	Notamacropus_eugenii
ENSG00000137054	POLR1E	86	72.145	ENSOPRG00000014206	POLR1E	100	72.145	Ochotona_princeps
ENSG00000137054	POLR1E	99	85.167	ENSODEG00000014565	POLR1E	97	85.167	Octodon_degus
ENSG00000137054	POLR1E	99	44.762	ENSONIG00000008921	polr1e	99	44.762	Oreochromis_niloticus
ENSG00000137054	POLR1E	75	64.151	ENSOANG00000021091	-	89	69.364	Ornithorhynchus_anatinus
ENSG00000137054	POLR1E	100	84.010	ENSOCUG00000024773	POLR1E	100	84.010	Oryctolagus_cuniculus
ENSG00000137054	POLR1E	98	44.310	ENSORLG00000005143	polr1e	98	44.310	Oryzias_latipes
ENSG00000137054	POLR1E	90	45.407	ENSORLG00020007271	polr1e	96	45.407	Oryzias_latipes_hni
ENSG00000137054	POLR1E	98	44.068	ENSORLG00015000137	polr1e	98	44.068	Oryzias_latipes_hsok
ENSG00000137054	POLR1E	96	42.998	ENSOMEG00000013264	polr1e	95	42.998	Oryzias_melastigma
ENSG00000137054	POLR1E	100	89.021	ENSOGAG00000012981	POLR1E	98	89.021	Otolemur_garnettii
ENSG00000137054	POLR1E	100	85.919	ENSOARG00000011465	POLR1E	97	85.919	Ovis_aries
ENSG00000137054	POLR1E	100	100.000	ENSPPAG00000034566	POLR1E	100	100.000	Pan_paniscus
ENSG00000137054	POLR1E	100	87.589	ENSPPRG00000005649	POLR1E	100	87.589	Panthera_pardus
ENSG00000137054	POLR1E	100	87.589	ENSPTIG00000009774	POLR1E	100	87.589	Panthera_tigris_altaica
ENSG00000137054	POLR1E	100	100.000	ENSPTRG00000020944	POLR1E	100	100.000	Pan_troglodytes
ENSG00000137054	POLR1E	100	98.329	ENSPANG00000025563	POLR1E	100	98.329	Papio_anubis
ENSG00000137054	POLR1E	98	45.694	ENSPKIG00000003562	polr1e	99	45.933	Paramormyrops_kingsleyae
ENSG00000137054	POLR1E	95	61.713	ENSPSIG00000003274	POLR1E	96	60.145	Pelodiscus_sinensis
ENSG00000137054	POLR1E	94	45.137	ENSPMGG00000024169	polr1e	96	45.137	Periophthalmus_magnuspinnatus
ENSG00000137054	POLR1E	100	79.475	ENSPEMG00000019151	-	97	79.475	Peromyscus_maniculatus_bairdii
ENSG00000137054	POLR1E	100	64.762	ENSPEMG00000022300	-	96	64.762	Peromyscus_maniculatus_bairdii
ENSG00000137054	POLR1E	95	73.232	ENSPCIG00000014798	POLR1E	97	73.232	Phascolarctos_cinereus
ENSG00000137054	POLR1E	96	42.459	ENSPFOG00000019627	polr1e	98	41.913	Poecilia_formosa
ENSG00000137054	POLR1E	98	43.341	ENSPLAG00000022679	polr1e	98	43.341	Poecilia_latipinna
ENSG00000137054	POLR1E	85	44.568	ENSPMEG00000022123	polr1e	92	44.568	Poecilia_mexicana
ENSG00000137054	POLR1E	93	44.020	ENSPREG00000009470	polr1e	95	43.434	Poecilia_reticulata
ENSG00000137054	POLR1E	100	98.329	ENSPPYG00000019061	POLR1E	100	98.329	Pongo_abelii
ENSG00000137054	POLR1E	72	69.637	ENSPCAG00000004891	POLR1E	99	69.637	Procavia_capensis
ENSG00000137054	POLR1E	100	91.169	ENSPCOG00000027448	POLR1E	100	91.169	Propithecus_coquereli
ENSG00000137054	POLR1E	94	88.832	ENSPVAG00000007940	POLR1E	99	83.090	Pteropus_vampyrus
ENSG00000137054	POLR1E	99	44.762	ENSPNYG00000001032	polr1e	99	44.762	Pundamilia_nyererei
ENSG00000137054	POLR1E	95	42.569	ENSPNAG00000006987	polr1e	95	42.569	Pygocentrus_nattereri
ENSG00000137054	POLR1E	99	78.606	ENSRNOG00000012664	Polr1e	96	78.606	Rattus_norvegicus
ENSG00000137054	POLR1E	99	93.735	ENSRBIG00000034214	POLR1E	100	97.375	Rhinopithecus_bieti
ENSG00000137054	POLR1E	100	97.852	ENSRROG00000031986	POLR1E	100	98.305	Rhinopithecus_roxellana
ENSG00000137054	POLR1E	100	94.033	ENSSBOG00000021415	POLR1E	100	94.033	Saimiri_boliviensis_boliviensis
ENSG00000137054	POLR1E	85	70.195	ENSSHAG00000016084	POLR1E	100	70.000	Sarcophilus_harrisii
ENSG00000137054	POLR1E	97	45.366	ENSSFOG00015002293	polr1e	99	45.985	Scleropages_formosus
ENSG00000137054	POLR1E	99	45.476	ENSSMAG00000011672	polr1e	93	45.476	Scophthalmus_maximus
ENSG00000137054	POLR1E	96	46.437	ENSSDUG00000022279	polr1e	96	46.437	Seriola_dumerili
ENSG00000137054	POLR1E	96	45.700	ENSSLDG00000024918	polr1e	96	45.700	Seriola_lalandi_dorsalis
ENSG00000137054	POLR1E	73	71.121	ENSSARG00000009810	-	81	71.121	Sorex_araneus
ENSG00000137054	POLR1E	98	64.407	ENSSPUG00000009499	POLR1E	99	64.407	Sphenodon_punctatus
ENSG00000137054	POLR1E	98	46.860	ENSSPAG00000021240	polr1e	99	46.394	Stegastes_partitus
ENSG00000137054	POLR1E	100	88.067	ENSSSCG00000005347	POLR1E	100	88.067	Sus_scrofa
ENSG00000137054	POLR1E	94	50.905	ENSTGUG00000007169	POLR1E	99	50.905	Taeniopygia_guttata
ENSG00000137054	POLR1E	98	43.750	ENSTRUG00000020779	polr1e	99	44.882	Takifugu_rubripes
ENSG00000137054	POLR1E	97	44.634	ENSTNIG00000017812	polr1e	98	44.634	Tetraodon_nigroviridis
ENSG00000137054	POLR1E	100	84.248	ENSTBEG00000013786	POLR1E	99	81.551	Tupaia_belangeri
ENSG00000137054	POLR1E	94	88.413	ENSTTRG00000008294	POLR1E	99	82.500	Tursiops_truncatus
ENSG00000137054	POLR1E	100	87.589	ENSUAMG00000012474	POLR1E	100	89.101	Ursus_americanus
ENSG00000137054	POLR1E	100	87.589	ENSUMAG00000011496	POLR1E	100	87.589	Ursus_maritimus
ENSG00000137054	POLR1E	89	75.701	ENSVPAG00000009048	POLR1E	100	75.701	Vicugna_pacos
ENSG00000137054	POLR1E	100	87.828	ENSVVUG00000019954	POLR1E	100	87.828	Vulpes_vulpes
ENSG00000137054	POLR1E	98	53.623	ENSXETG00000006533	polr1e	99	53.623	Xenopus_tropicalis
ENSG00000137054	POLR1E	91	50.000	ENSXCOG00000013706	polr1e	97	42.998	Xiphophorus_couchianus
ENSG00000137054	POLR1E	96	44.226	ENSXMAG00000012484	polr1e	97	44.226	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0001179	RNA polymerase I transcription factor binding	-	IEA	Function
GO:0001188	RNA polymerase I preinitiation complex assembly	-	IEA	Process
GO:0001650	fibrillar center	-	IDA	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	ISS	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process