EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000137074 (Gene tree)
Gene ID: 54840
Gene Symbol: APTX
Alias: FLJ20157|AOA|AOA1|EAOH|EOAHA|AXA1
Full Name: aprataxin
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 52,563 bases
Position: chr9:32,972,606-33,025,168
Accession: 15984
RBP type: canonical RBP
Summary: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000380357	DcpS_C	PF11969.8	4.7e-33	1	1
ENSP00000311547	DcpS_C	PF11969.8	5.3e-33	1	1
ENSP00000369153	DcpS_C	PF11969.8	5.6e-33	1	1
ENSP00000419042	DcpS_C	PF11969.8	5.9e-33	1	1
ENSP00000369145	DcpS_C	PF11969.8	6.5e-33	1	1
ENSP00000400806	DcpS_C	PF11969.8	6.5e-33	1	1
ENSP00000419846	DcpS_C	PF11969.8	6.5e-33	1	1
ENSP00000420263	DcpS_C	PF11969.8	6.5e-33	1	1
ENSP00000369147	DcpS_C	PF11969.8	7e-33	1	1
ENSP00000369141	DcpS_C	PF11969.8	2.7e-32	1	1
ENSP00000369140	DcpS_C	PF11969.8	1.2e-21	1	1
ENSP00000419020	DcpS_C	PF11969.8	1.6e-21	1	1
ENSP00000417649	DcpS_C	PF11969.8	2.5e-07	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16547001	Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities.	J Biol Chem	2006 May 19	Kijas AW	-
24362567	Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity.	Nature	2014 Feb 6	Tumbale P	doi: 10.1038/nature12824
16777843	Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription.	Hum Mol Genet	2006 Jul 15	Becherel OJ	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000379817	APTX-204	2106	-	ENSP00000369145	342 (aa)	-	Q7Z2E3
ENST00000486724	APTX-228	556	-	-	- (aa)	-	-
ENST00000379813	APTX-203	1121	-	ENSP00000369141	336 (aa)	-	A0A0A0MRW7
ENST00000379812	APTX-202	599	XM_017014836	ENSP00000369140	198 (aa)	XP_016870325	F8W6G5
ENST00000494649	APTX-230	2099	-	ENSP00000417634	49 (aa)	-	Q7Z2E3
ENST00000485479	APTX-227	1986	-	ENSP00000418144	49 (aa)	-	Q7Z2E3
ENST00000496030	APTX-233	633	-	-	- (aa)	-	-
ENST00000480031	APTX-224	674	-	ENSP00000417684	52 (aa)	-	F8WBD6
ENST00000460945	APTX-210	542	-	-	- (aa)	-	-
ENST00000460940	APTX-209	1874	-	ENSP00000418311	49 (aa)	-	Q7Z2E3
ENST00000467331	APTX-214	2101	-	ENSP00000418733	49 (aa)	-	Q7Z2E3
ENST00000309615	APTX-201	1859	XM_006716792	ENSP00000311547	288 (aa)	XP_006716855	Q7Z2E3
ENST00000479656	APTX-223	1881	-	ENSP00000420071	49 (aa)	-	Q7Z2E3
ENST00000489583	APTX-229	397	-	-	- (aa)	-	-
ENST00000473221	APTX-217	687	-	ENSP00000419020	216 (aa)	-	C9JZ40
ENST00000473270	APTX-218	645	-	-	- (aa)	-	-
ENST00000397172	APTX-207	1740	-	ENSP00000380357	284 (aa)	-	Q7Z2E3
ENST00000472896	APTX-216	1759	-	ENSP00000417804	49 (aa)	-	Q7Z2E3
ENST00000379819	APTX-205	1820	-	ENSP00000369147	356 (aa)	-	Q7Z2E3
ENST00000379825	APTX-206	2023	XM_017014838	ENSP00000369153	306 (aa)	XP_016870327	Q7Z2E3
ENST00000494973	APTX-231	547	-	-	- (aa)	-	-
ENST00000464632	APTX-212	679	-	ENSP00000418069	63 (aa)	-	E7EUY4
ENST00000465003	APTX-213	1991	-	ENSP00000419430	85 (aa)	-	Q6JV79
ENST00000468275	APTX-215	1455	-	ENSP00000420263	342 (aa)	-	Q7Z2E3
ENST00000436040	APTX-208	2168	XM_006716791	ENSP00000400806	342 (aa)	XP_006716854	Q7Z2E3
ENST00000463596	APTX-211	1345	-	ENSP00000419846	342 (aa)	-	Q7Z2E3
ENST00000478279	APTX-222	684	-	ENSP00000419597	99 (aa)	-	E7EVB7
ENST00000482687	APTX-225	1879	-	ENSP00000419289	192 (aa)	-	Q7Z2E3
ENST00000483148	APTX-226	1764	-	ENSP00000419723	85 (aa)	-	Q6JV79
ENST00000476858	APTX-220	1068	-	ENSP00000419042	302 (aa)	-	Q7Z2E3
ENST00000495360	APTX-232	1313	-	ENSP00000419623	49 (aa)	-	Q7Z2E3
ENST00000474658	APTX-219	952	-	ENSP00000417750	74 (aa)	-	F8WBM3
ENST00000477119	APTX-221	568	-	ENSP00000417649	155 (aa)	-	C9J8U3

Gene Model

Click here to download ENSG00000137074's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000137074	Pancreatic Neoplasms	1.3410000E-004	19648918

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000137074	rs4879656	9	33012384	A	Menopause (age at onset)	26414677	[0.081-0.159] years decrease	0.12	EFO_0004704
ENSG00000137074	rs10813912	9	32975212	?	Age at menopause	30595370			EFO_0004704

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000137074's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000137074	APTX	98	72.632	ENSAPOG00000008785	aptx	99	61.062	Acanthochromis_polyacanthus
ENSG00000137074	APTX	99	94.972	ENSAMEG00000007648	APTX	99	88.952	Ailuropoda_melanoleuca
ENSG00000137074	APTX	92	66.667	ENSACIG00000002035	aptx	99	59.875	Amphilophus_citrinellus
ENSG00000137074	APTX	99	61.357	ENSAOCG00000000634	aptx	99	61.357	Amphiprion_ocellaris
ENSG00000137074	APTX	99	61.357	ENSAPEG00000017253	aptx	99	61.357	Amphiprion_percula
ENSG00000137074	APTX	92	71.579	ENSATEG00000017383	aptx	99	60.767	Anabas_testudineus
ENSG00000137074	APTX	82	69.756	ENSAPLG00000015645	APTX	99	60.938	Anas_platyrhynchos
ENSG00000137074	APTX	95	76.087	ENSACAG00000003581	APTX	96	61.561	Anolis_carolinensis
ENSG00000137074	APTX	100	98.343	ENSANAG00000030160	APTX	100	92.978	Aotus_nancymaae
ENSG00000137074	APTX	94	70.455	ENSACLG00000018887	aptx	100	61.062	Astatotilapia_calliptera
ENSG00000137074	APTX	92	77.895	ENSAMXG00000039899	aptx	99	59.412	Astyanax_mexicanus
ENSG00000137074	APTX	100	89.181	ENSBTAG00000013947	APTX	99	89.244	Bos_taurus
ENSG00000137074	APTX	100	93.567	ENSCJAG00000007940	APTX	100	93.294	Callithrix_jacchus
ENSG00000137074	APTX	99	92.647	ENSCAFG00000001812	APTX	99	92.647	Canis_familiaris
ENSG00000137074	APTX	99	92.647	ENSCAFG00020015598	APTX	99	92.647	Canis_lupus_dingo
ENSG00000137074	APTX	98	94.475	ENSCHIG00000012896	APTX	100	88.889	Capra_hircus
ENSG00000137074	APTX	100	90.643	ENSTSYG00000003041	APTX	100	90.643	Carlito_syrichta
ENSG00000137074	APTX	90	90.909	ENSCAPG00000013470	APTX	100	92.683	Cavia_aperea
ENSG00000137074	APTX	99	89.443	ENSCPOG00000005975	APTX	100	89.535	Cavia_porcellus
ENSG00000137074	APTX	100	94.152	ENSCCAG00000036783	APTX	100	93.878	Cebus_capucinus
ENSG00000137074	APTX	100	96.784	ENSCATG00000042639	APTX	100	96.181	Cercocebus_atys
ENSG00000137074	APTX	100	86.550	ENSCLAG00000012185	APTX	100	91.304	Chinchilla_lanigera
ENSG00000137074	APTX	100	97.953	ENSCSAG00000009885	APTX	100	97.472	Chlorocebus_sabaeus
ENSG00000137074	APTX	95	77.901	ENSCPBG00000023973	APTX	98	64.972	Chrysemys_picta_bellii
ENSG00000137074	APTX	93	54.348	ENSCING00000008741	-	98	40.160	Ciona_intestinalis
ENSG00000137074	APTX	91	51.445	ENSCSAVG00000008038	-	97	40.390	Ciona_savignyi
ENSG00000137074	APTX	100	96.199	ENSCANG00000037253	APTX	100	96.199	Colobus_angolensis_palliatus
ENSG00000137074	APTX	94	93.258	ENSCGRG00001000705	Aptx	99	90.110	Cricetulus_griseus_chok1gshd
ENSG00000137074	APTX	94	93.258	ENSCGRG00000014159	Aptx	99	90.110	Cricetulus_griseus_crigri
ENSG00000137074	APTX	99	58.065	ENSCSEG00000009549	aptx	99	58.065	Cynoglossus_semilaevis
ENSG00000137074	APTX	92	72.632	ENSCVAG00000011942	aptx	99	58.333	Cyprinodon_variegatus
ENSG00000137074	APTX	92	74.737	ENSDARG00000027143	aptx	99	57.988	Danio_rerio
ENSG00000137074	APTX	99	90.000	ENSDNOG00000018498	APTX	99	88.102	Dasypus_novemcinctus
ENSG00000137074	APTX	100	84.840	ENSDORG00000002139	Aptx	100	91.304	Dipodomys_ordii
ENSG00000137074	APTX	64	40.449	FBgn0038704	CG5316	87	47.541	Drosophila_melanogaster
ENSG00000137074	APTX	85	85.656	ENSETEG00000012459	APTX	79	86.429	Echinops_telfairi
ENSG00000137074	APTX	96	59.783	ENSEBUG00000013914	aptx	97	46.944	Eptatretus_burgeri
ENSG00000137074	APTX	100	90.351	ENSEASG00005004566	APTX	100	90.351	Equus_asinus_asinus
ENSG00000137074	APTX	96	95.580	ENSECAG00000012674	APTX	93	90.407	Equus_caballus
ENSG00000137074	APTX	93	93.684	ENSEEUG00000010693	APTX	99	84.262	Erinaceus_europaeus
ENSG00000137074	APTX	99	94.737	ENSFCAG00000008728	APTX	99	92.647	Felis_catus
ENSG00000137074	APTX	94	76.136	ENSFALG00000001230	APTX	99	64.740	Ficedula_albicollis
ENSG00000137074	APTX	99	85.000	ENSFDAG00000013752	APTX	100	84.239	Fukomys_damarensis
ENSG00000137074	APTX	92	51.613	ENSFHEG00000021328	aptx	73	56.294	Fundulus_heteroclitus
ENSG00000137074	APTX	99	56.342	ENSGMOG00000012505	aptx	99	56.342	Gadus_morhua
ENSG00000137074	APTX	95	73.262	ENSGALG00000001954	APTX	100	61.714	Gallus_gallus
ENSG00000137074	APTX	94	69.832	ENSGAFG00000005086	aptx	99	59.292	Gambusia_affinis
ENSG00000137074	APTX	93	70.950	ENSGACG00000017887	aptx	99	60.000	Gasterosteus_aculeatus
ENSG00000137074	APTX	94	78.409	ENSGAGG00000013230	APTX	99	65.439	Gopherus_agassizii
ENSG00000137074	APTX	100	97.419	ENSGGOG00000014232	APTX	100	97.895	Gorilla_gorilla
ENSG00000137074	APTX	94	70.455	ENSHBUG00000021058	aptx	100	61.062	Haplochromis_burtoni
ENSG00000137074	APTX	94	93.258	ENSHGLG00000015093	APTX	100	93.220	Heterocephalus_glaber_female
ENSG00000137074	APTX	94	93.258	ENSHGLG00100013482	APTX	100	93.220	Heterocephalus_glaber_male
ENSG00000137074	APTX	99	59.531	ENSHCOG00000018216	aptx	96	59.531	Hippocampus_comes
ENSG00000137074	APTX	94	74.157	ENSIPUG00000017548	aptx	99	60.117	Ictalurus_punctatus
ENSG00000137074	APTX	95	91.713	ENSSTOG00000005185	APTX	100	86.510	Ictidomys_tridecemlineatus
ENSG00000137074	APTX	98	85.417	ENSJJAG00000015653	Aptx	100	82.405	Jaculus_jaculus
ENSG00000137074	APTX	98	60.417	ENSKMAG00000000117	aptx	99	58.702	Kryptolebias_marmoratus
ENSG00000137074	APTX	94	68.182	ENSLBEG00000021489	APTX	93	68.182	Labrus_bergylta
ENSG00000137074	APTX	94	68.182	ENSLBEG00000015353	aptx	93	68.182	Labrus_bergylta
ENSG00000137074	APTX	97	74.419	ENSLACG00000003376	APTX	99	62.216	Latimeria_chalumnae
ENSG00000137074	APTX	96	79.348	ENSLOCG00000011556	aptx	96	62.791	Lepisosteus_oculatus
ENSG00000137074	APTX	95	97.802	ENSLAFG00000005665	APTX	99	92.105	Loxodonta_africana
ENSG00000137074	APTX	100	96.732	ENSMFAG00000043141	APTX	100	96.732	Macaca_fascicularis
ENSG00000137074	APTX	100	97.661	ENSMMUG00000007724	APTX	100	97.024	Macaca_mulatta
ENSG00000137074	APTX	100	97.076	ENSMNEG00000042341	APTX	100	97.076	Macaca_nemestrina
ENSG00000137074	APTX	100	97.076	ENSMLEG00000035137	APTX	100	97.076	Mandrillus_leucophaeus
ENSG00000137074	APTX	94	68.715	ENSMAMG00000018377	aptx	99	58.997	Mastacembelus_armatus
ENSG00000137074	APTX	94	69.832	ENSMZEG00005022621	aptx	100	60.767	Maylandia_zebra
ENSG00000137074	APTX	64	74.033	ENSMGAG00000005736	APTX	100	74.033	Meleagris_gallopavo
ENSG00000137074	APTX	94	91.954	ENSMAUG00000006039	Aptx	99	89.560	Mesocricetus_auratus
ENSG00000137074	APTX	99	92.669	ENSMICG00000006603	APTX	100	90.449	Microcebus_murinus
ENSG00000137074	APTX	94	95.652	ENSMOCG00000000869	Aptx	99	89.560	Microtus_ochrogaster
ENSG00000137074	APTX	92	75.789	ENSMMOG00000007028	aptx	99	62.647	Mola_mola
ENSG00000137074	APTX	92	86.667	ENSMODG00000003365	APTX	100	62.784	Monodelphis_domestica
ENSG00000137074	APTX	92	66.667	ENSMALG00000003828	aptx	99	56.471	Monopterus_albus
ENSG00000137074	APTX	92	93.333	MGP_CAROLIEiJ_G0025897	-	99	89.560	Mus_caroli
ENSG00000137074	APTX	94	92.179	ENSMUSG00000028411	Aptx	99	90.659	Mus_musculus
ENSG00000137074	APTX	94	93.182	MGP_PahariEiJ_G0024020	Aptx	94	93.182	Mus_pahari
ENSG00000137074	APTX	94	92.179	MGP_SPRETEiJ_G0026846	Aptx	97	85.841	Mus_spretus
ENSG00000137074	APTX	99	90.294	ENSMPUG00000004290	APTX	99	90.294	Mustela_putorius_furo
ENSG00000137074	APTX	99	91.176	ENSMLUG00000016081	APTX	95	91.228	Myotis_lucifugus
ENSG00000137074	APTX	95	93.333	ENSNGAG00000016314	Aptx	100	88.043	Nannospalax_galili
ENSG00000137074	APTX	99	61.176	ENSNBRG00000014199	aptx	100	61.176	Neolamprologus_brichardi
ENSG00000137074	APTX	100	98.264	ENSNLEG00000032184	APTX	100	98.264	Nomascus_leucogenys
ENSG00000137074	APTX	94	74.576	ENSMEUG00000004153	APTX	99	65.015	Notamacropus_eugenii
ENSG00000137074	APTX	92	95.556	ENSOPRG00000012403	APTX	100	81.759	Ochotona_princeps
ENSG00000137074	APTX	88	93.023	ENSODEG00000000097	-	100	80.623	Octodon_degus
ENSG00000137074	APTX	95	94.318	ENSODEG00000015832	-	100	87.390	Octodon_degus
ENSG00000137074	APTX	95	70.455	ENSONIG00000014541	aptx	83	60.411	Oreochromis_niloticus
ENSG00000137074	APTX	90	81.818	ENSOANG00000009878	APTX	98	63.816	Ornithorhynchus_anatinus
ENSG00000137074	APTX	99	90.588	ENSOCUG00000000738	-	99	90.378	Oryctolagus_cuniculus
ENSG00000137074	APTX	94	86.957	ENSOCUG00000025059	-	93	93.443	Oryctolagus_cuniculus
ENSG00000137074	APTX	99	57.478	ENSORLG00000006237	aptx	100	57.478	Oryzias_latipes
ENSG00000137074	APTX	99	57.478	ENSORLG00020021478	aptx	100	57.478	Oryzias_latipes_hni
ENSG00000137074	APTX	92	69.714	ENSORLG00015021873	aptx	100	58.544	Oryzias_latipes_hsok
ENSG00000137074	APTX	99	50.416	ENSOMEG00000007875	aptx	96	50.416	Oryzias_melastigma
ENSG00000137074	APTX	99	93.923	ENSOGAG00000005388	APTX	99	89.266	Otolemur_garnettii
ENSG00000137074	APTX	100	95.028	ENSOARG00000009598	APTX	100	86.798	Ovis_aries
ENSG00000137074	APTX	100	99.415	ENSPPAG00000030295	APTX	100	99.346	Pan_paniscus
ENSG00000137074	APTX	99	92.647	ENSPPRG00000017524	APTX	99	92.647	Panthera_pardus
ENSG00000137074	APTX	99	92.647	ENSPTIG00000020000	APTX	99	92.647	Panthera_tigris_altaica
ENSG00000137074	APTX	100	100.000	ENSPTRG00000020850	APTX	100	99.415	Pan_troglodytes
ENSG00000137074	APTX	100	97.953	ENSPANG00000025301	APTX	100	97.321	Papio_anubis
ENSG00000137074	APTX	94	70.899	ENSPKIG00000013601	aptx	99	62.029	Paramormyrops_kingsleyae
ENSG00000137074	APTX	99	78.571	ENSPSIG00000010521	APTX	99	67.787	Pelodiscus_sinensis
ENSG00000137074	APTX	93	71.591	ENSPMGG00000018649	aptx	99	57.771	Periophthalmus_magnuspinnatus
ENSG00000137074	APTX	94	96.591	ENSPEMG00000007747	Aptx	99	90.110	Peromyscus_maniculatus_bairdii
ENSG00000137074	APTX	95	53.684	ENSPMAG00000008417	aptx	98	47.443	Petromyzon_marinus
ENSG00000137074	APTX	94	84.091	ENSPCIG00000029852	APTX	100	68.376	Phascolarctos_cinereus
ENSG00000137074	APTX	92	68.889	ENSPFOG00000004992	aptx	99	59.292	Poecilia_formosa
ENSG00000137074	APTX	92	68.889	ENSPFOG00000005131	-	99	59.587	Poecilia_formosa
ENSG00000137074	APTX	92	68.889	ENSPLAG00000007906	aptx	99	59.587	Poecilia_latipinna
ENSG00000137074	APTX	92	68.889	ENSPLAG00000007960	APTX	99	59.587	Poecilia_latipinna
ENSG00000137074	APTX	92	68.889	ENSPMEG00000018504	aptx	99	59.882	Poecilia_mexicana
ENSG00000137074	APTX	92	68.889	ENSPMEG00000019789	APTX	99	59.587	Poecilia_mexicana
ENSG00000137074	APTX	92	68.889	ENSPREG00000004375	aptx	99	58.804	Poecilia_reticulata
ENSG00000137074	APTX	100	98.538	ENSPPYG00000019142	APTX	100	98.034	Pongo_abelii
ENSG00000137074	APTX	94	95.652	ENSPCAG00000010014	APTX	99	76.246	Procavia_capensis
ENSG00000137074	APTX	100	94.737	ENSPCOG00000016780	APTX	100	94.737	Propithecus_coquereli
ENSG00000137074	APTX	99	89.474	ENSPVAG00000011468	APTX	99	88.669	Pteropus_vampyrus
ENSG00000137074	APTX	94	70.455	ENSPNYG00000007675	aptx	100	61.062	Pundamilia_nyererei
ENSG00000137074	APTX	92	75.789	ENSPNAG00000015984	aptx	99	57.941	Pygocentrus_nattereri
ENSG00000137074	APTX	94	92.179	ENSRNOG00000006582	Aptx	99	82.006	Rattus_norvegicus
ENSG00000137074	APTX	100	96.875	ENSRBIG00000042913	APTX	100	96.784	Rhinopithecus_bieti
ENSG00000137074	APTX	100	96.528	ENSRROG00000035395	APTX	100	96.491	Rhinopithecus_roxellana
ENSG00000137074	APTX	100	94.444	ENSSBOG00000025215	APTX	100	94.444	Saimiri_boliviensis_boliviensis
ENSG00000137074	APTX	95	84.270	ENSSHAG00000012205	APTX	96	69.298	Sarcophilus_harrisii
ENSG00000137074	APTX	94	76.404	ENSSFOG00015009267	aptx	99	66.286	Scleropages_formosus
ENSG00000137074	APTX	94	70.455	ENSSMAG00000008839	aptx	99	61.947	Scophthalmus_maximus
ENSG00000137074	APTX	99	61.947	ENSSDUG00000001989	aptx	99	61.947	Seriola_dumerili
ENSG00000137074	APTX	99	62.242	ENSSLDG00000004915	aptx	99	62.242	Seriola_lalandi_dorsalis
ENSG00000137074	APTX	96	78.495	ENSSPUG00000008994	APTX	84	78.495	Sphenodon_punctatus
ENSG00000137074	APTX	99	62.242	ENSSPAG00000020373	aptx	99	62.242	Stegastes_partitus
ENSG00000137074	APTX	99	91.176	ENSSSCG00000011001	APTX	99	91.176	Sus_scrofa
ENSG00000137074	APTX	94	73.034	ENSTGUG00000001441	APTX	99	63.265	Taeniopygia_guttata
ENSG00000137074	APTX	94	68.539	ENSTRUG00000009794	aptx	99	59.292	Takifugu_rubripes
ENSG00000137074	APTX	93	69.767	ENSTNIG00000010570	aptx	98	60.882	Tetraodon_nigroviridis
ENSG00000137074	APTX	94	93.478	ENSTBEG00000008504	APTX	99	82.670	Tupaia_belangeri
ENSG00000137074	APTX	99	85.526	ENSTTRG00000007384	APTX	99	83.988	Tursiops_truncatus
ENSG00000137074	APTX	100	90.643	ENSUAMG00000003700	APTX	100	90.062	Ursus_americanus
ENSG00000137074	APTX	100	90.643	ENSUMAG00000005837	APTX	100	90.643	Ursus_maritimus
ENSG00000137074	APTX	95	90.909	ENSVPAG00000001297	APTX	80	91.304	Vicugna_pacos
ENSG00000137074	APTX	99	92.647	ENSVVUG00000021130	APTX	99	92.647	Vulpes_vulpes
ENSG00000137074	APTX	94	72.727	ENSXETG00000024143	aptx	99	62.000	Xenopus_tropicalis
ENSG00000137074	APTX	94	69.832	ENSXCOG00000005020	aptx	99	57.345	Xiphophorus_couchianus
ENSG00000137074	APTX	94	70.391	ENSXMAG00000022086	aptx	96	60.177	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000012	single strand break repair	21873635.	IBA	Process
GO:0000012	single strand break repair	17519253.	IDA	Process
GO:0000785	chromatin	15044383.	IDA	Component
GO:0000790	nuclear chromatin	20008512.	IDA	Component
GO:0003682	chromatin binding	15044383.	IDA	Function
GO:0003684	damaged DNA binding	14755728.	IDA	Function
GO:0003690	double-stranded DNA binding	16547001.17276982.	IDA	Function
GO:0003697	single-stranded DNA binding	21873635.	IBA	Function
GO:0003725	double-stranded RNA binding	21873635.	IBA	Function
GO:0003725	double-stranded RNA binding	16547001.	IDA	Function
GO:0005515	protein binding	14755728.15044383.15380105.15555565.16439205.16713569.16777843.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	15044383.16777843.	IDA	Component
GO:0005730	nucleolus	15044383.16777843.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006266	DNA ligation	-	IEA	Process
GO:0006302	double-strand break repair	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	15044383.	IMP	Process
GO:0008967	phosphoglycolate phosphatase activity	17519253.	IDA	Function
GO:0016311	dephosphorylation	-	IEA	Process
GO:0030983	mismatched DNA binding	21873635.	IBA	Function
GO:0031647	regulation of protein stability	16777843.	IMP	Process
GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	21873635.	IBA	Function
GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	16547001.16964241.17276982.17519253.	IDA	Function
GO:0042542	response to hydrogen peroxide	15044383.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0047485	protein N-terminus binding	16777843.	IPI	Function
GO:0051219	phosphoprotein binding	20008512.	IPI	Function
GO:0090305	nucleic acid phosphodiester bond hydrolysis	-	IEA	Process
GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase	-	IEA	Function
GO:1990165	single-strand break-containing DNA binding	21873635.	IBA	Function