EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000137133 (Gene tree)
Gene ID: 84681
Gene Symbol: HINT2
Alias: -
Full Name: histidine triad nucleotide binding protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 2,520 bases
Position: chr9:35,812,960-35,815,479
Accession: 18344
RBP type: canonical RBP
Summary: Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000259667	DcpS_C	PF11969.8	6.4e-21	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23682076	Progesterone enhances calcitriol antitumor activity by upregulating vitamin D receptor expression and promoting apoptosis in endometrial cancer cells.	Cancer Prev Res (Phila)	2013 Jul	Lee LR	doi: 10.1158/1940-6207.CAPR-12-0493

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000490578	HINT2-207	717	-	-	- (aa)	-	-
ENST00000474848	HINT2-205	853	-	-	- (aa)	-	-
ENST00000472085	HINT2-204	569	-	-	- (aa)	-	-
ENST00000259667	HINT2-201	628	XM_024447702	ENSP00000259667	163 (aa)	XP_024303470	Q9BX68
ENST00000471774	HINT2-203	443	-	-	- (aa)	-	-
ENST00000461169	HINT2-202	734	-	-	- (aa)	-	-
ENST00000474908	HINT2-206	2167	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000137133's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000137133's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000137133	HINT2	78	67.717	ENSAPOG00000005822	hint2	95	73.043	Acanthochromis_polyacanthus
ENSG00000137133	HINT2	93	90.132	ENSAMEG00000009919	HINT2	84	95.620	Ailuropoda_melanoleuca
ENSG00000137133	HINT2	80	67.424	ENSACIG00000024176	hint2	85	67.424	Amphilophus_citrinellus
ENSG00000137133	HINT2	80	66.667	ENSAOCG00000018892	hint2	99	66.929	Amphiprion_ocellaris
ENSG00000137133	HINT2	80	66.667	ENSAPEG00000012800	hint2	86	66.667	Amphiprion_percula
ENSG00000137133	HINT2	80	68.182	ENSATEG00000001240	hint2	83	68.182	Anabas_testudineus
ENSG00000137133	HINT2	55	80.000	ENSACAG00000003036	HINT2	87	80.000	Anolis_carolinensis
ENSG00000137133	HINT2	84	97.810	ENSANAG00000036887	HINT2	88	95.804	Aotus_nancymaae
ENSG00000137133	HINT2	80	67.424	ENSACLG00000020144	hint2	92	67.424	Astatotilapia_calliptera
ENSG00000137133	HINT2	79	68.702	ENSAMXG00000016137	hint2	79	68.702	Astyanax_mexicanus
ENSG00000137133	HINT2	92	94.000	ENSBTAG00000011444	HINT2	91	95.620	Bos_taurus
ENSG00000137133	HINT2	100	93.865	ENSCJAG00000010068	HINT2	87	95.745	Callithrix_jacchus
ENSG00000137133	HINT2	100	88.344	ENSCAFG00000002240	HINT2	88	90.909	Canis_familiaris
ENSG00000137133	HINT2	100	85.366	ENSCAFG00020017487	HINT2	88	87.500	Canis_lupus_dingo
ENSG00000137133	HINT2	92	95.333	ENSCHIG00000010130	HINT2	88	95.804	Capra_hircus
ENSG00000137133	HINT2	100	80.120	ENSTSYG00000000640	-	90	86.713	Carlito_syrichta
ENSG00000137133	HINT2	86	92.857	ENSTSYG00000030020	-	88	91.608	Carlito_syrichta
ENSG00000137133	HINT2	83	94.853	ENSCAPG00000007065	HINT2	92	94.853	Cavia_aperea
ENSG00000137133	HINT2	100	89.571	ENSCPOG00000040327	HINT2	88	92.308	Cavia_porcellus
ENSG00000137133	HINT2	84	97.080	ENSCCAG00000023291	HINT2	88	95.105	Cebus_capucinus
ENSG00000137133	HINT2	100	94.479	ENSCATG00000033387	HINT2	88	95.105	Cercocebus_atys
ENSG00000137133	HINT2	60	81.633	ENSCLAG00000013492	-	94	81.633	Chinchilla_lanigera
ENSG00000137133	HINT2	100	90.184	ENSCLAG00000002682	-	88	92.308	Chinchilla_lanigera
ENSG00000137133	HINT2	100	95.706	ENSCSAG00000010622	HINT2	88	96.503	Chlorocebus_sabaeus
ENSG00000137133	HINT2	93	66.038	ENSCPBG00000002797	HINT2	96	70.000	Chrysemys_picta_bellii
ENSG00000137133	HINT2	77	61.417	ENSCING00000023160	-	99	60.938	Ciona_intestinalis
ENSG00000137133	HINT2	80	59.542	ENSCING00000011420	-	75	59.542	Ciona_intestinalis
ENSG00000137133	HINT2	84	59.124	ENSCSAVG00000006544	-	82	59.124	Ciona_savignyi
ENSG00000137133	HINT2	77	61.600	ENSCSAVG00000008721	-	93	61.600	Ciona_savignyi
ENSG00000137133	HINT2	83	97.059	ENSCANG00000042118	HINT2	83	97.059	Colobus_angolensis_palliatus
ENSG00000137133	HINT2	100	88.344	ENSCGRG00001022361	Hint2	86	92.143	Cricetulus_griseus_chok1gshd
ENSG00000137133	HINT2	100	86.503	ENSCGRG00000017831	Hint2	86	92.143	Cricetulus_griseus_crigri
ENSG00000137133	HINT2	77	60.317	ENSCSEG00000003930	hint1	98	60.317	Cynoglossus_semilaevis
ENSG00000137133	HINT2	80	66.667	ENSCSEG00000018825	hint2	98	66.935	Cynoglossus_semilaevis
ENSG00000137133	HINT2	77	61.111	ENSCVAG00000013656	hint1	98	61.111	Cyprinodon_variegatus
ENSG00000137133	HINT2	80	65.152	ENSCVAG00000015693	hint2	90	65.152	Cyprinodon_variegatus
ENSG00000137133	HINT2	79	67.176	ENSDARG00000100938	hint2	81	67.176	Danio_rerio
ENSG00000137133	HINT2	77	62.698	ENSDARG00000103824	hint1	98	62.698	Danio_rerio
ENSG00000137133	HINT2	87	92.254	ENSDNOG00000009083	HINT2	88	91.608	Dasypus_novemcinctus
ENSG00000137133	HINT2	87	89.437	ENSDORG00000006268	Hint2	88	88.811	Dipodomys_ordii
ENSG00000137133	HINT2	77	60.317	FBgn0031459	CG2862	99	59.843	Drosophila_melanogaster
ENSG00000137133	HINT2	87	88.028	ENSETEG00000017929	HINT2	87	88.028	Echinops_telfairi
ENSG00000137133	HINT2	77	61.905	ENSEBUG00000015709	-	99	61.417	Eptatretus_burgeri
ENSG00000137133	HINT2	79	65.672	ENSEBUG00000009253	hint2	78	65.672	Eptatretus_burgeri
ENSG00000137133	HINT2	100	89.571	ENSEASG00005014042	HINT2	88	90.210	Equus_asinus_asinus
ENSG00000137133	HINT2	100	90.184	ENSECAG00000000037	HINT2	88	90.909	Equus_caballus
ENSG00000137133	HINT2	83	93.382	ENSEEUG00000011866	HINT2	100	93.382	Erinaceus_europaeus
ENSG00000137133	HINT2	77	60.317	ENSELUG00000016515	hint1	98	60.317	Esox_lucius
ENSG00000137133	HINT2	98	59.119	ENSELUG00000014618	HINT2	84	68.217	Esox_lucius
ENSG00000137133	HINT2	93	91.447	ENSFCAG00000012755	HINT2	88	93.007	Felis_catus
ENSG00000137133	HINT2	70	74.561	ENSFALG00000000137	HINT2	100	74.561	Ficedula_albicollis
ENSG00000137133	HINT2	100	90.798	ENSFDAG00000007090	HINT2	88	93.007	Fukomys_damarensis
ENSG00000137133	HINT2	77	63.492	ENSFHEG00000001761	hint1	70	62.992	Fundulus_heteroclitus
ENSG00000137133	HINT2	96	60.000	ENSFHEG00000004041	hint2	79	61.224	Fundulus_heteroclitus
ENSG00000137133	HINT2	77	59.524	ENSGMOG00000005105	hint1	99	59.055	Gadus_morhua
ENSG00000137133	HINT2	98	68.323	ENSGALG00000027418	-	88	71.429	Gallus_gallus
ENSG00000137133	HINT2	77	61.905	ENSGAFG00000001228	hint1	98	61.905	Gambusia_affinis
ENSG00000137133	HINT2	80	66.667	ENSGAFG00000016884	hint2	99	66.929	Gambusia_affinis
ENSG00000137133	HINT2	90	54.902	ENSGAGG00000014845	HINT2	51	58.779	Gopherus_agassizii
ENSG00000137133	HINT2	100	100.000	ENSGGOG00000011265	HINT2	100	100.000	Gorilla_gorilla
ENSG00000137133	HINT2	80	67.424	ENSHBUG00000007106	hint2	92	67.424	Haplochromis_burtoni
ENSG00000137133	HINT2	100	88.957	ENSHGLG00000018803	HINT2	88	90.210	Heterocephalus_glaber_female
ENSG00000137133	HINT2	100	88.344	ENSHGLG00100009260	HINT2	88	90.210	Heterocephalus_glaber_male
ENSG00000137133	HINT2	81	64.925	ENSHCOG00000008201	hint2	98	66.406	Hippocampus_comes
ENSG00000137133	HINT2	86	63.380	ENSIPUG00000015540	Hint2	85	63.380	Ictalurus_punctatus
ENSG00000137133	HINT2	77	61.111	ENSIPUG00000003460	hint1	98	61.111	Ictalurus_punctatus
ENSG00000137133	HINT2	87	95.070	ENSSTOG00000006975	HINT2	88	94.406	Ictidomys_tridecemlineatus
ENSG00000137133	HINT2	91	88.514	ENSJJAG00000005863	Hint2	91	88.811	Jaculus_jaculus
ENSG00000137133	HINT2	78	68.217	ENSKMAG00000007624	hint2	93	68.217	Kryptolebias_marmoratus
ENSG00000137133	HINT2	80	66.667	ENSLBEG00000026254	hint2	87	66.667	Labrus_bergylta
ENSG00000137133	HINT2	80	65.385	ENSLACG00000013400	HINT2	92	63.910	Latimeria_chalumnae
ENSG00000137133	HINT2	71	71.304	ENSLOCG00000011981	hint2	91	71.304	Lepisosteus_oculatus
ENSG00000137133	HINT2	100	90.184	ENSLAFG00000015022	HINT2	88	90.210	Loxodonta_africana
ENSG00000137133	HINT2	100	95.706	ENSMFAG00000034091	HINT2	88	96.503	Macaca_fascicularis
ENSG00000137133	HINT2	100	95.706	ENSMMUG00000016337	HINT2	88	96.503	Macaca_mulatta
ENSG00000137133	HINT2	100	95.092	ENSMNEG00000044230	HINT2	87	96.479	Macaca_nemestrina
ENSG00000137133	HINT2	83	96.324	ENSMLEG00000029409	HINT2	100	96.324	Mandrillus_leucophaeus
ENSG00000137133	HINT2	79	64.122	ENSMAMG00000006530	hint2	84	64.122	Mastacembelus_armatus
ENSG00000137133	HINT2	80	67.424	ENSMZEG00005013690	hint2	92	67.424	Maylandia_zebra
ENSG00000137133	HINT2	100	87.117	ENSMAUG00000008164	Hint2	86	90.714	Mesocricetus_auratus
ENSG00000137133	HINT2	85	94.964	ENSMICG00000002572	HINT2	88	93.007	Microcebus_murinus
ENSG00000137133	HINT2	100	89.571	ENSMOCG00000022371	Hint2	88	91.608	Microtus_ochrogaster
ENSG00000137133	HINT2	77	63.492	ENSMMOG00000007854	hint1	98	63.492	Mola_mola
ENSG00000137133	HINT2	80	65.909	ENSMMOG00000017956	hint2	73	65.909	Mola_mola
ENSG00000137133	HINT2	79	85.938	ENSMODG00000006947	HINT2	100	85.938	Monodelphis_domestica
ENSG00000137133	HINT2	80	65.909	ENSMALG00000005121	hint2	80	65.909	Monopterus_albus
ENSG00000137133	HINT2	77	59.524	ENSMALG00000001063	hint1	98	59.524	Monopterus_albus
ENSG00000137133	HINT2	100	85.276	MGP_CAROLIEiJ_G0025948	Hint2	86	87.857	Mus_caroli
ENSG00000137133	HINT2	100	85.890	ENSMUSG00000028470	Hint2	88	86.713	Mus_musculus
ENSG00000137133	HINT2	100	84.663	MGP_PahariEiJ_G0024093	Hint2	86	87.857	Mus_pahari
ENSG00000137133	HINT2	100	84.663	MGP_SPRETEiJ_G0026909	Hint2	86	87.857	Mus_spretus
ENSG00000137133	HINT2	100	85.890	ENSMPUG00000005589	HINT2	88	87.413	Mustela_putorius_furo
ENSG00000137133	HINT2	94	90.196	ENSMLUG00000023856	HINT2	88	91.608	Myotis_lucifugus
ENSG00000137133	HINT2	93	91.447	ENSNGAG00000003065	Hint2	88	92.308	Nannospalax_galili
ENSG00000137133	HINT2	91	62.914	ENSNBRG00000022918	hint2	97	73.043	Neolamprologus_brichardi
ENSG00000137133	HINT2	100	96.933	ENSNLEG00000033123	HINT2	100	96.933	Nomascus_leucogenys
ENSG00000137133	HINT2	84	93.431	ENSODEG00000013829	HINT2	88	91.608	Octodon_degus
ENSG00000137133	HINT2	91	85.811	ENSOCUG00000006472	-	88	86.713	Oryctolagus_cuniculus
ENSG00000137133	HINT2	95	86.792	ENSOCUG00000027206	-	84	93.571	Oryctolagus_cuniculus
ENSG00000137133	HINT2	80	68.462	ENSORLG00000001235	hint2	72	68.462	Oryzias_latipes
ENSG00000137133	HINT2	94	61.039	ENSORLG00020009336	hint2	100	71.429	Oryzias_latipes_hni
ENSG00000137133	HINT2	80	68.462	ENSORLG00015018872	hint2	100	71.429	Oryzias_latipes_hsok
ENSG00000137133	HINT2	77	69.048	ENSOMEG00000012866	hint2	85	69.048	Oryzias_melastigma
ENSG00000137133	HINT2	100	90.184	ENSOGAG00000011830	HINT2	88	90.909	Otolemur_garnettii
ENSG00000137133	HINT2	92	95.333	ENSOARG00000011729	HINT2	88	95.804	Ovis_aries
ENSG00000137133	HINT2	100	100.000	ENSPPAG00000002836	HINT2	100	100.000	Pan_paniscus
ENSG00000137133	HINT2	93	91.447	ENSPPRG00000020701	HINT2	88	93.706	Panthera_pardus
ENSG00000137133	HINT2	84	95.620	ENSPTIG00000015400	HINT2	88	95.620	Panthera_tigris_altaica
ENSG00000137133	HINT2	100	100.000	ENSPTRG00000020923	HINT2	100	100.000	Pan_troglodytes
ENSG00000137133	HINT2	100	95.092	ENSPANG00000025487	HINT2	88	95.804	Papio_anubis
ENSG00000137133	HINT2	86	66.197	ENSPKIG00000024049	hint2	92	73.043	Paramormyrops_kingsleyae
ENSG00000137133	HINT2	77	60.317	ENSPKIG00000021119	hint1	87	59.843	Paramormyrops_kingsleyae
ENSG00000137133	HINT2	92	63.816	ENSPMGG00000006589	hint2	89	74.107	Periophthalmus_magnuspinnatus
ENSG00000137133	HINT2	100	88.344	ENSPEMG00000014390	Hint2	88	90.210	Peromyscus_maniculatus_bairdii
ENSG00000137133	HINT2	83	62.222	ENSPMAG00000006075	hint1	90	62.222	Petromyzon_marinus
ENSG00000137133	HINT2	98	57.738	ENSPMAG00000002715	hint2	86	58.667	Petromyzon_marinus
ENSG00000137133	HINT2	87	59.459	ENSPCIG00000021660	-	71	62.879	Phascolarctos_cinereus
ENSG00000137133	HINT2	80	65.152	ENSPFOG00000007209	hint2	80	65.152	Poecilia_formosa
ENSG00000137133	HINT2	77	61.905	ENSPFOG00000012020	hint1	98	61.905	Poecilia_formosa
ENSG00000137133	HINT2	77	61.905	ENSPLAG00000003800	hint1	98	61.905	Poecilia_latipinna
ENSG00000137133	HINT2	86	63.014	ENSPLAG00000004768	hint2	94	71.304	Poecilia_latipinna
ENSG00000137133	HINT2	96	57.862	ENSPMEG00000017523	hint2	79	65.152	Poecilia_mexicana
ENSG00000137133	HINT2	77	61.905	ENSPMEG00000016327	hint1	98	61.905	Poecilia_mexicana
ENSG00000137133	HINT2	79	66.412	ENSPREG00000008004	hint2	80	66.412	Poecilia_reticulata
ENSG00000137133	HINT2	77	61.905	ENSPREG00000003867	hint1	98	61.905	Poecilia_reticulata
ENSG00000137133	HINT2	100	96.933	ENSPPYG00000019082	HINT2	100	96.933	Pongo_abelii
ENSG00000137133	HINT2	84	95.620	ENSPCOG00000023948	HINT2	88	93.706	Propithecus_coquereli
ENSG00000137133	HINT2	93	89.474	ENSPVAG00000003028	HINT2	88	91.608	Pteropus_vampyrus
ENSG00000137133	HINT2	79	67.176	ENSPNYG00000017024	hint2	95	72.034	Pundamilia_nyererei
ENSG00000137133	HINT2	90	62.162	ENSPNAG00000029879	hint2	87	67.939	Pygocentrus_nattereri
ENSG00000137133	HINT2	100	85.276	ENSRNOG00000015866	Hint2	88	87.413	Rattus_norvegicus
ENSG00000137133	HINT2	100	96.933	ENSRBIG00000044870	HINT2	100	96.933	Rhinopithecus_bieti
ENSG00000137133	HINT2	100	96.319	ENSRROG00000035123	HINT2	100	96.319	Rhinopithecus_roxellana
ENSG00000137133	HINT2	100	95.092	ENSSBOG00000025840	HINT2	88	95.105	Saimiri_boliviensis_boliviensis
ENSG00000137133	HINT2	67	57.273	ENSSHAG00000012507	-	87	57.273	Sarcophilus_harrisii
ENSG00000137133	HINT2	84	88.321	ENSSHAG00000013965	HINT2	99	88.321	Sarcophilus_harrisii
ENSG00000137133	HINT2	71	69.565	ENSSFOG00015001540	hint2	85	62.044	Scleropages_formosus
ENSG00000137133	HINT2	99	59.877	ENSSMAG00000008382	hint2	74	68.939	Scophthalmus_maximus
ENSG00000137133	HINT2	80	65.909	ENSSDUG00000022415	hint2	73	65.909	Seriola_dumerili
ENSG00000137133	HINT2	80	65.152	ENSSLDG00000004617	hint2	97	66.400	Seriola_lalandi_dorsalis
ENSG00000137133	HINT2	80	65.909	ENSSPAG00000013723	hint2	70	65.909	Stegastes_partitus
ENSG00000137133	HINT2	70	73.684	ENSTGUG00000001823	HINT2	100	73.684	Taeniopygia_guttata
ENSG00000137133	HINT2	77	61.905	ENSTRUG00000009900	hint1	98	61.905	Takifugu_rubripes
ENSG00000137133	HINT2	80	67.424	ENSTRUG00000023015	hint2	97	70.248	Takifugu_rubripes
ENSG00000137133	HINT2	100	60.714	ENSTNIG00000015580	hint2	85	65.493	Tetraodon_nigroviridis
ENSG00000137133	HINT2	91	92.617	ENSTBEG00000013020	HINT2	86	94.286	Tupaia_belangeri
ENSG00000137133	HINT2	100	92.025	ENSTTRG00000011932	HINT2	88	95.804	Tursiops_truncatus
ENSG00000137133	HINT2	87	94.366	ENSUAMG00000009907	HINT2	63	93.706	Ursus_americanus
ENSG00000137133	HINT2	91	89.865	ENSUMAG00000007451	HINT2	82	94.245	Ursus_maritimus
ENSG00000137133	HINT2	87	95.775	ENSVPAG00000005592	HINT2	88	95.105	Vicugna_pacos
ENSG00000137133	HINT2	96	81.250	ENSVVUG00000020192	HINT2	59	86.111	Vulpes_vulpes
ENSG00000137133	HINT2	60	60.784	ENSXETG00000005083	hint2	63	60.784	Xenopus_tropicalis
ENSG00000137133	HINT2	84	62.774	ENSXCOG00000009621	hint2	90	71.304	Xiphophorus_couchianus
ENSG00000137133	HINT2	77	61.905	ENSXMAG00000023903	hint1	98	61.905	Xiphophorus_maculatus
ENSG00000137133	HINT2	78	65.891	ENSXMAG00000026925	hint2	81	65.891	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0005730	nucleolus	-	IDA	Component
GO:0005739	mitochondrion	-	IDA	Component
GO:0005739	mitochondrion	-	ISS	Component
GO:0006694	steroid biosynthetic process	-	IEA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0016042	lipid catabolic process	-	IEA	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:2000757	negative regulation of peptidyl-lysine acetylation	-	IEA	Process